Mrpl45

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL intron excision ratio chr10_82310797_82313694 0.34 0.17 8.4e-05 0.13 0.13 0.12 0.18 5.4e-04 5.0e-04 7.7e-04 4.8e-05
2 NAcc mRNA stability Mrpl45 0.1 0.06 9.6e-10 0.1 0.09 0.1 0.1 1.4e-11 1.0e-10 2.9e-11 1.8e-11
3 IL mRNA stability Mrpl45 0.21 0.14 4.3e-03 0.11 0.02 0.03 0.06 1.5e-03 8.9e-02 6.4e-02 1.4e-02
4 IL intron excision ratio chr10_82310718_82313694 0.33 0.17 1.2e-04 0.14 0.13 0.09 0.17 4.0e-04 5.5e-04 4.1e-03 7.7e-05
5 OFC gene expression Mrpl45 0.85 0.05 0.0e+00 0.44 0.46 0.45 0.48 8.8e-12 1.8e-12 3.4e-12 4.0e-13
6 Liver gene expression Mrpl45 0.68 0.06 0.0e+00 0.57 0.6 0.6 0.6 1.2e-77 2.5e-82 2.4e-83 3.2e-83
7 OFC intron excision ratio chr10_82310797_82313694 0.29 0.19 7.1e-03 0.09 0.07 0.07 0.1 3.6e-03 7.6e-03 9.0e-03 2.3e-03
8 NAcc intron excision ratio chr10_82310718_82313694 0.19 0.11 8.9e-07 0.06 0.05 0.05 0.06 1.5e-07 2.0e-06 6.8e-07 1.5e-07
9 Adipose gene expression Mrpl45 0.6 0.08 0.0e+00 0.45 0.45 0.45 0.46 7.3e-55 8.1e-56 1.3e-55 7.0e-56
10 BLA gene expression Mrpl45 0.75 0.07 0.0e+00 0.58 0.62 0.62 0.63 5.6e-37 6.8e-42 1.6e-41 1.2e-42
11 IL gene expression Mrpl45 0.9 0.04 0.0e+00 0.44 0.37 0.41 0.43 5.2e-12 7.5e-10 7.0e-11 1.2e-11
12 RMTg gene expression Mrpl45 0.67 0.14 1.0e-09 0.25 0.27 0.26 0.27 2.0e-07 6.2e-08 1.1e-07 6.0e-08
13 pVTA gene expression Mrpl45 0.79 0.05 0.0e+00 0.72 0.73 0.73 0.74 3.6e-44 2.2e-44 4.0e-45 2.3e-45
14 pVTA mRNA stability Mrpl45 0.16 0.09 1.1e-05 0.15 0.13 0.12 0.14 4.6e-07 4.2e-06 1.2e-05 1.0e-06
15 NAcc gene expression Mrpl45 0.72 0.05 0.0e+00 0.73 0.74 0.75 0.75 2.1e-124 5.7e-128 2.3e-129 2.6e-129
16 PL intron excision ratio chr10_82310718_82313694 0.15 0.1 2.0e-07 0.08 0.07 0.07 0.08 6.9e-09 1.5e-08 8.2e-08 6.6e-09
17 PL gene expression Mrpl45 0.74 0.03 0.0e+00 0.75 0.76 0.77 0.77 5.7e-125 2.8e-129 2.2e-130 1.2e-129
18 LHb gene expression Mrpl45 0.82 0.07 3.3e-16 0.44 0.44 0.44 0.47 1.3e-11 1.0e-11 1.2e-11 1.0e-12
19 Brain gene expression Mrpl45 0.61 0.04 0.0e+00 0.62 0.63 0.63 0.63 3.1e-73 2.5e-75 3.7e-75 3.0e-75
20 PL mRNA stability Mrpl45 0.18 0.08 6.6e-14 0.13 0.12 0.12 0.13 2.4e-14 3.7e-13 2.5e-13 5.3e-14
21 Brain intron excision ratio chr10_82310718_82313694 0.42 0.27 3.0e-07 0.09 0.08 0.08 0.09 1.5e-08 1.2e-07 6.4e-08 2.6e-08
22 BLA mRNA stability Mrpl45 0.32 0.15 4.0e-07 0.13 0.13 0.14 0.14 1.7e-07 1.4e-07 6.1e-08 6.8e-08
23 RMTg mRNA stability Mrpl45 0.38 0.2 5.9e-04 0.12 0.06 0.04 0.1 4.2e-04 1.1e-02 2.5e-02 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.01.62.5-1.6-1.0-1.01.51.4-1.3-1.01.41.31.3-1.21.31.3-1.2-1.31.3-1.21.21.3-1.3-1.3-1.4-1.3
Area under the delay curve1.21.32.20.41.51.5-0.6-1.01.21.3-1.2-1.2-1.11.2-1.1-1.11.21.2-1.11.2-1.2-1.01.11.10.71.1
BMI with tail5.116.724.4-2.3-3.7-3.62.73.9-4.9-3.64.34.34.9-4.34.34.3-4.2-4.44.4-4.24.33.9-4.3-4.3-3.3-4.3
BMI without tail0.10.10.5-0.1-0.1-0.10.10.4-0.7-0.10.40.30.7-0.50.40.4-0.3-0.30.3-0.30.40.2-0.2-0.2-0.1-0.3
Body weight1.45.811.73.42.82.8-3.3-2.41.52.8-2.3-2.2-1.52.1-2.3-2.32.42.1-2.22.3-2.2-2.52.22.22.62.1
Weight adjusted by age0.40.40.70.80.30.3-0.7-0.80.70.4-0.7-0.8-0.60.8-0.6-0.60.60.7-0.70.7-0.8-0.60.60.60.80.8
Bone surface0.00.00.20.20.40.4-0.2-0.2-0.00.4-0.0-0.10.00.2-0.1-0.10.20.1-0.10.1-0.2-0.20.10.10.30.0
Bone volume0.10.20.5-0.4-0.1-0.10.40.4-0.7-0.20.50.50.7-0.40.50.5-0.5-0.50.5-0.50.40.4-0.5-0.5-0.4-0.6
Breakpoint value in progressive ratio session3.43.75.01.81.91.9-1.9-1.92.21.9-1.9-1.9-2.11.9-1.9-1.91.91.9-1.91.9-1.9-1.91.91.91.81.9
Number of licking bursts0.10.10.4-0.6-0.2-0.20.50.4-0.1-0.10.40.4-0.0-0.40.40.4-0.2-0.30.4-0.30.40.4-0.3-0.3-0.3-0.4
Context. condit. distance diff. score0.00.00.10.2-0.1-0.1-0.2-0.1-0.3-0.10.10.10.30.00.10.1-0.0-0.10.1-0.10.10.0-0.1-0.10.2-0.1
Locomotion velocity, session 10.20.20.3-0.0-0.3-0.30.10.4-0.5-0.40.50.50.5-0.50.50.5-0.5-0.50.5-0.50.50.3-0.4-0.4-0.3-0.5
Locomotion distance, session 13.54.55.42.32.12.1-2.3-2.12.22.1-2.1-2.1-2.32.0-2.1-2.12.02.1-2.12.1-2.0-2.12.12.12.02.1
Locomotion velocity, session 22.83.33.51.71.91.9-1.7-1.91.71.9-1.8-1.8-1.71.8-1.9-1.91.81.8-1.81.8-1.8-1.81.81.81.61.8
Locomotion distance, session 23.75.26.52.12.42.4-2.1-2.22.52.4-2.2-2.3-2.62.2-2.3-2.22.32.3-2.22.3-2.2-2.32.32.32.12.2
Locomotion velocity, session 30.30.40.50.50.60.6-0.5-0.60.50.6-0.6-0.7-0.60.6-0.7-0.70.60.6-0.70.6-0.6-0.60.60.60.40.6
Locomotion distance, session 34.24.65.01.92.12.1-2.0-2.02.22.2-2.1-2.2-2.22.0-2.2-2.22.22.2-2.22.2-2.1-2.22.22.22.12.2
Stereotopy head waving bouts, day 33.94.66.1-2.3-2.3-2.32.32.2-2.4-2.22.02.02.5-2.12.02.0-2.2-2.01.9-2.12.12.1-2.0-2.0-2.2-2.0
Stereotopy head waving duration, day 31.82.13.3-1.4-1.5-1.51.41.4-1.8-1.51.41.41.8-1.41.41.4-1.5-1.41.3-1.41.41.4-1.3-1.4-1.5-1.3
Locomotion velocity, session 71.92.12.61.31.51.5-1.3-1.41.51.5-1.5-1.5-1.61.4-1.4-1.51.61.5-1.41.5-1.4-1.41.51.51.31.4
Locomotion distance, session 74.96.27.41.92.52.5-2.1-2.32.72.5-2.6-2.5-2.72.4-2.5-2.52.62.6-2.52.6-2.5-2.52.62.62.32.5
Stereotopy head waving bouts, day 71.41.52.1-1.2-1.4-1.51.31.0-1.3-1.41.21.21.4-1.01.21.2-1.3-1.21.1-1.21.11.2-1.3-1.3-1.1-1.2
Stereotopy head waving duration, day 71.01.21.8-0.9-1.3-1.31.00.9-1.1-1.31.11.01.2-1.01.11.1-1.2-1.11.0-1.11.01.1-1.1-1.1-0.9-1.0
Locomotion velocity, session 80.40.52.11.40.60.7-1.3-0.80.40.6-0.5-0.5-0.40.5-0.5-0.50.50.4-0.50.5-0.5-0.70.50.51.10.5
Locomotion distance, session 81.62.43.01.71.51.5-1.7-1.61.41.5-1.6-1.6-1.51.5-1.6-1.61.51.5-1.61.5-1.5-1.61.61.51.71.5
Degree of sensitization distance0.10.10.10.30.20.2-0.3-0.30.20.2-0.3-0.3-0.30.3-0.3-0.30.20.2-0.20.3-0.3-0.20.30.30.20.2
Degree of sensitization stereotypy0.91.01.4-1.2-1.2-1.21.20.8-0.7-1.11.00.90.8-0.71.01.0-1.0-0.90.9-1.00.91.0-1.0-1.1-0.9-1.0
Conditioned locomotion0.10.10.4-0.4-0.3-0.30.40.4-0.6-0.30.40.40.5-0.40.40.3-0.2-0.40.4-0.40.30.4-0.3-0.3-0.4-0.3
Cocaine response after cond. corrected1.71.93.7-1.4-1.3-1.31.41.3-1.9-1.31.21.31.9-1.21.31.3-1.4-1.31.3-1.31.21.3-1.2-1.2-1.4-1.1
Cocaine response after cond. not corrected0.50.61.6-1.1-0.8-0.81.00.7-1.3-0.70.50.71.2-0.50.60.6-0.7-0.60.6-0.60.50.7-0.6-0.6-0.9-0.5
Cocaine response before conditioning1.11.42.20.51.11.0-0.6-1.11.41.2-1.3-1.2-1.51.2-1.2-1.21.41.3-1.21.3-1.2-1.11.21.21.01.2
Saline control response0.00.00.2-0.4-0.3-0.30.40.10.0-0.2-0.00.10.00.00.10.1-0.2-0.10.0-0.1-0.00.2-0.1-0.1-0.40.0
Bone: connectivity density0.50.71.9-1.4-0.7-0.71.30.9-0.7-0.60.90.90.6-0.70.90.9-0.7-0.80.9-0.80.80.9-0.8-0.8-1.0-0.9
Bone: cortical apparent density0.20.21.5-0.70.20.20.50.21.20.4-0.2-0.3-1.20.1-0.2-0.20.40.4-0.20.4-0.2-0.20.50.40.10.4
Bone: cortical area0.10.20.30.10.50.5-0.2-0.30.30.6-0.4-0.4-0.40.4-0.5-0.50.40.4-0.50.4-0.4-0.40.30.30.30.4
Bone: cortical porosity0.40.40.9-0.9-0.7-0.70.90.5-0.7-0.70.50.60.8-0.40.50.5-0.6-0.60.5-0.60.50.7-0.6-0.6-0.9-0.5
Bone: cortical porosity0.20.20.7-0.9-0.4-0.50.80.3-0.5-0.40.20.40.6-0.20.30.3-0.3-0.30.3-0.30.30.4-0.3-0.3-0.8-0.3
Bone: cortical thickness0.30.40.7-0.00.70.6-0.1-0.50.70.8-0.7-0.7-0.80.6-0.8-0.70.60.8-0.80.7-0.7-0.60.70.70.50.7
Bone: cortical thickness1.21.42.0-0.01.11.1-0.2-1.11.21.3-1.3-1.3-1.21.4-1.4-1.31.11.4-1.41.3-1.4-1.11.31.30.51.3
Bone: cortical tissue density0.20.31.6-0.60.30.20.40.11.30.4-0.3-0.3-1.20.1-0.2-0.30.40.5-0.30.4-0.3-0.20.50.50.10.4
Condit. Reinf. active minus inactive responses0.00.00.1-0.40.10.10.30.20.10.10.20.1-0.1-0.20.10.1-0.0-0.10.2-0.10.20.1-0.0-0.1-0.1-0.2
Condit. Reinf. active-inactive response ratio0.50.50.9-1.0-0.5-0.60.90.8-0.6-0.50.80.70.6-0.70.70.8-0.7-0.70.7-0.70.70.7-0.6-0.7-0.8-0.8
Condit. Reinf. active responses0.10.20.4-0.6-0.2-0.20.60.6-0.1-0.20.50.40.1-0.50.40.4-0.3-0.30.4-0.30.50.4-0.4-0.4-0.4-0.4
Condit. Reinf. inactive responses0.00.00.2-0.4-0.2-0.20.40.30.1-0.10.20.2-0.1-0.30.10.1-0.1-0.10.2-0.10.20.2-0.2-0.2-0.3-0.1
Incentive salience index mean0.10.10.4-0.60.0-0.00.50.40.20.10.20.1-0.2-0.30.20.2-0.1-0.10.2-0.10.20.2-0.1-0.1-0.3-0.2
Condit. Reinf. lever presses0.10.10.3-0.6-0.0-0.00.50.50.40.00.30.1-0.4-0.40.10.1-0.1-0.00.1-0.00.30.1-0.1-0.1-0.3-0.1
Condit. Reinf. active minus inactive responses0.30.40.9-0.9-0.4-0.40.80.6-0.4-0.40.60.60.4-0.50.60.6-0.4-0.60.6-0.60.50.6-0.6-0.6-1.0-0.7
Condit. Reinf. active-inactive response ratio1.31.41.7-1.2-1.1-1.11.21.0-1.0-1.11.21.21.0-1.01.31.2-1.1-1.21.2-1.21.11.2-1.2-1.2-1.3-1.3
Condit. Reinf. active responses0.20.30.9-0.9-0.3-0.30.90.5-0.3-0.30.50.50.3-0.40.50.5-0.3-0.40.5-0.50.40.5-0.5-0.5-0.9-0.6
Condit. Reinf. inactive responses0.10.10.7-0.9-0.2-0.20.70.30.1-0.10.10.1-0.1-0.20.10.10.0-0.00.1-0.10.10.2-0.1-0.1-0.6-0.1
Condit. Reinf. lever presses0.20.20.50.20.50.5-0.3-0.30.70.5-0.5-0.4-0.70.4-0.4-0.40.60.5-0.40.4-0.5-0.50.60.60.30.4
Condit. Reinf. lever reinforcers received0.10.20.6-0.8-0.3-0.30.70.4-0.1-0.20.30.30.2-0.20.40.3-0.2-0.30.4-0.30.30.4-0.3-0.3-0.7-0.4
Conditioned reinforcement - actives2.32.33.2-1.7-1.4-1.31.71.8-1.4-1.41.51.51.4-1.71.41.4-1.4-1.41.4-1.41.61.4-1.5-1.5-1.8-1.5
Conditioned reinforcement - inactives0.30.41.3-1.2-0.4-0.41.00.80.0-0.50.60.50.0-0.60.50.5-0.5-0.50.5-0.50.60.6-0.6-0.6-1.0-0.6
Conditioned locomotion3.34.05.7-2.0-1.9-1.92.02.1-2.2-1.92.02.02.0-2.11.91.9-1.9-2.02.0-2.02.02.0-1.9-1.9-2.4-2.0
Patch foraging indifference point 0 sec0.30.51.1-1.0-0.6-0.61.00.7-0.9-0.60.50.60.9-0.50.60.5-0.5-0.50.5-0.60.50.7-0.7-0.7-1.1-0.6
Patch foraging indifference point AUC0.00.00.10.1-0.1-0.0-0.1-0.00.10.10.20.2-0.0-0.10.10.1-0.1-0.20.2-0.20.20.2-0.2-0.20.3-0.3
Delay disc. indifference point, 0s delay0.50.51.20.00.60.6-0.2-0.90.80.6-0.9-0.7-0.81.1-0.8-0.80.70.8-0.70.7-0.9-0.50.70.70.20.8
Delay disc. indifference point, 16s delay0.20.20.80.10.80.9-0.2-0.20.30.7-0.4-0.4-0.30.3-0.4-0.40.50.5-0.40.5-0.4-0.40.40.40.20.4
Delay disc. indifference point, 2s delay0.91.01.40.01.01.1-0.2-0.91.01.1-1.2-1.0-1.01.2-1.1-1.11.01.1-1.11.0-1.1-0.81.01.00.31.0
Delay disc. indifference point, 24s delay1.11.01.70.81.31.3-0.9-1.11.01.1-1.0-1.0-0.91.2-0.9-0.91.01.0-0.81.0-1.1-0.91.01.01.20.9
Delay disc. indifference point, 4s delay6.87.28.81.83.03.0-2.0-2.52.82.9-2.8-2.8-2.72.7-2.7-2.72.82.9-2.82.8-2.8-2.62.72.71.92.8
Delay disc. indifference point, 8s delay0.20.20.5-0.10.70.70.0-0.20.50.6-0.4-0.5-0.40.4-0.5-0.50.50.6-0.40.5-0.4-0.30.50.50.10.5
Indifference point function ln k0.20.20.40.30.40.3-0.3-0.40.20.2-0.6-0.6-0.20.5-0.6-0.60.50.6-0.60.5-0.5-0.50.50.50.30.6
Indifference point function log k0.20.20.40.30.40.3-0.3-0.40.20.2-0.6-0.6-0.20.5-0.6-0.60.50.6-0.60.5-0.5-0.50.50.50.30.6
Patch foraging total patch changes 0 sec0.10.20.6-0.7-0.4-0.40.70.4-0.8-0.40.30.30.7-0.30.30.3-0.3-0.30.3-0.40.30.4-0.4-0.4-0.8-0.3
Patch foraging total patch changes 12 sec0.81.02.9-1.7-0.9-0.91.61.0-0.9-0.70.90.90.8-0.80.90.8-0.7-0.80.9-0.90.91.1-1.0-1.0-1.5-1.0
Patch foraging total patch changes 18 sec1.82.42.7-1.3-1.5-1.51.41.5-1.6-1.41.51.51.6-1.51.51.5-1.5-1.61.6-1.61.61.6-1.6-1.6-1.6-1.7
Patch foraging total patch changes 24 sec1.01.21.6-1.2-1.1-1.11.10.9-1.2-0.91.01.21.3-0.91.11.1-1.0-1.11.2-1.10.91.1-1.0-1.0-1.3-1.0
Patch foraging total patch changes 6 sec1.11.62.5-1.3-1.1-1.01.31.6-1.3-0.81.31.31.2-1.51.31.3-1.1-1.31.4-1.21.31.4-1.2-1.2-1.4-1.3
Patch foraging time to switch 0 sec0.30.40.8-0.7-0.5-0.50.70.7-0.5-0.60.70.70.5-0.70.70.7-0.5-0.70.8-0.60.70.6-0.6-0.6-0.9-0.6
Patch foraging water rate 0 sec0.10.20.50.50.50.5-0.5-0.50.00.7-0.5-0.4-0.00.5-0.5-0.50.50.4-0.50.4-0.4-0.40.40.40.70.3
Patch foraging water rate 12 sec1.11.61.91.31.31.2-1.3-1.41.11.3-1.3-1.2-1.01.4-1.3-1.31.31.3-1.31.3-1.3-1.31.21.21.31.3
Patch foraging water rate 18 sec1.21.62.00.71.31.2-0.8-1.31.31.3-1.3-1.3-1.31.4-1.3-1.31.41.4-1.31.4-1.4-1.21.31.31.01.3
Patch foraging water rate 24 sec0.00.10.2-0.4-0.0-0.10.40.1-0.40.20.10.20.3-0.10.20.2-0.1-0.20.1-0.20.10.3-0.3-0.3-0.3-0.2
Patch foraging water rate 6 sec0.00.00.1-0.4-0.2-0.30.4-0.1-0.0-0.2-0.00.1-0.10.20.00.0-0.0-0.00.0-0.10.00.1-0.1-0.1-0.1-0.2
Seeking ratio, delayed vs. immediate footshock0.50.50.7-0.5-0.8-0.70.50.5-0.8-0.80.70.80.8-0.60.80.8-0.8-0.80.8-0.80.70.8-0.8-0.8-0.6-0.7
Distance traveled before self-admin0.50.51.00.40.70.7-0.5-0.70.80.8-0.8-0.7-1.00.7-0.5-0.60.80.8-0.60.8-0.7-0.70.90.90.40.7
Distance traveled after self-admin0.10.10.60.4-0.5-0.5-0.2-0.1-0.8-0.30.00.20.6-0.00.30.2-0.1-0.20.2-0.10.10.1-0.1-0.10.2-0.1
Extensor digitorum longus weight0.83.310.53.22.12.1-3.0-1.91.21.8-1.5-1.5-1.31.4-1.5-1.41.61.3-1.41.5-1.4-1.81.51.52.41.3
Bone: elastic displacement0.00.10.1-0.2-0.2-0.20.20.3-0.3-0.20.20.20.3-0.30.20.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.3-0.1
Bone: elastic work0.30.40.60.50.70.7-0.6-0.50.50.7-0.7-0.7-0.50.5-0.7-0.60.70.7-0.70.7-0.6-0.70.70.70.50.7
Bone: endosteal estimation0.30.71.61.31.01.0-1.2-1.10.30.9-0.9-0.8-0.31.0-0.9-0.80.80.7-0.80.7-0.8-0.90.60.61.00.7
Bone: endosteal perimeter0.10.10.60.80.50.5-0.7-0.4-0.00.4-0.3-0.30.00.3-0.3-0.30.40.2-0.20.2-0.2-0.40.10.10.40.2
Epididymis fat weight0.30.71.00.90.90.9-0.9-1.00.71.0-0.8-0.8-0.70.9-0.9-0.90.90.8-0.80.8-0.9-0.80.70.70.80.7
Delta time in closed arm before/after self-admin0.30.31.31.10.40.4-1.0-0.30.30.4-0.4-0.4-0.30.1-0.3-0.30.50.4-0.30.5-0.3-0.60.50.50.90.4
Delta time in open arm before/after self-admin0.10.10.3-0.4-0.1-0.10.40.60.0-0.20.40.3-0.0-0.60.30.3-0.3-0.20.2-0.30.40.3-0.3-0.3-0.4-0.3
Diff in mean of infusions in LGA sessions0.00.00.1-0.10.10.00.1-0.20.3-0.10.00.10.10.20.10.1-0.2-0.10.1-0.2-0.00.1-0.1-0.1-0.1-0.3
Delay discount exponential model param1.81.93.2-0.8-1.8-1.80.91.3-1.4-1.61.41.41.3-1.41.41.4-1.5-1.51.4-1.51.41.3-1.4-1.4-1.0-1.4
Extinction: sum of active levers before priming1.61.62.21.41.11.1-1.4-1.41.11.2-1.3-1.3-1.11.4-1.2-1.21.21.3-1.31.3-1.3-1.11.21.21.51.4
Active lever presses in extinction session 60.10.10.3-0.3-0.3-0.30.40.4-0.4-0.30.40.40.2-0.50.50.5-0.2-0.40.5-0.30.40.4-0.2-0.2-0.0-0.3
Bone: final force0.00.10.5-0.7-0.0-0.10.60.0-0.30.00.10.10.20.10.00.0-0.0-0.10.0-0.10.00.2-0.2-0.2-0.4-0.2
Bone: final moment0.00.00.3-0.60.10.00.5-0.1-0.20.1-0.0-0.00.10.2-0.1-0.10.00.1-0.10.0-0.10.1-0.1-0.1-0.4-0.0
Food consumed during 24 hour testing period0.81.01.31.11.01.0-1.1-1.11.10.9-1.0-0.9-1.11.0-0.9-0.91.00.9-0.90.9-0.9-1.00.90.91.10.9
Glucose0.10.20.5-0.10.40.4-0.0-0.3-0.00.5-0.4-0.4-0.20.4-0.4-0.40.70.5-0.40.5-0.4-0.30.50.50.10.4
Heart weight0.00.10.50.70.00.0-0.6-0.1-0.4-0.10.00.00.3-0.10.00.1-0.1-0.10.0-0.10.10.0-0.1-0.10.3-0.1
Delay discount hyperbolic model param2.22.33.6-0.8-1.9-1.91.01.4-1.6-1.71.61.61.5-1.61.61.6-1.6-1.71.5-1.61.61.4-1.5-1.5-1.0-1.5
Intermittent access intake day 1-15 change0.90.92.0-0.7-0.8-0.80.71.4-1.1-0.91.01.01.0-1.40.90.9-0.9-0.90.9-0.91.11.0-0.8-0.8-0.6-0.8
Intermittent access intake escalation1.21.22.4-0.8-1.0-1.00.91.5-1.3-1.01.11.11.2-1.51.01.0-1.1-1.01.0-1.01.21.0-0.9-0.9-0.9-0.9
Intermittent access intake escalation 20.60.61.4-0.3-0.7-0.70.41.1-1.0-0.70.90.90.9-1.20.80.8-0.7-0.80.8-0.71.00.8-0.7-0.7-0.4-0.7
Intermitt. access day 1 inactive lever presses0.20.20.6-0.8-0.3-0.40.70.80.0-0.30.50.40.1-0.70.40.4-0.3-0.30.5-0.40.60.4-0.4-0.4-0.7-0.4
Intermitt. access day 15 inactive lever presses3.94.36.2-2.2-1.8-1.82.12.5-1.5-1.92.22.21.7-2.42.22.2-2.0-2.02.2-2.12.22.1-2.0-2.0-2.2-2.0
Intermitt. access escalation Index0.20.20.6-0.0-0.2-0.20.10.7-0.8-0.20.50.40.7-0.80.30.3-0.2-0.40.4-0.30.60.3-0.5-0.5-0.3-0.4
Intermittent access day 1 total infusions0.00.00.10.00.00.0-0.0-0.20.1-0.0-0.2-0.1-0.10.3-0.1-0.10.00.1-0.10.1-0.2-0.10.10.10.20.1
Intermittent access day 15 total infusions0.30.30.7-0.5-0.5-0.50.50.9-0.6-0.50.60.70.5-0.90.50.5-0.5-0.50.5-0.50.60.5-0.5-0.5-0.4-0.5
Intermittent access terminal intake (last 3 days)0.60.71.6-0.7-0.7-0.70.71.2-0.7-0.80.90.90.7-1.20.80.8-0.8-0.80.8-0.81.00.8-0.8-0.8-0.6-0.8
Intermittent access total infusions0.00.00.1-0.00.00.00.00.3-0.1-0.10.10.20.1-0.30.10.1-0.1-0.10.1-0.10.10.1-0.1-0.10.1-0.1
Intermittent access day 1 locomotion0.00.00.0-0.20.00.00.10.20.2-0.0-0.00.1-0.1-0.2-0.0-0.00.00.0-0.00.00.0-0.00.10.1-0.10.1
Intermittent access day 15 total locomotion0.50.61.1-0.6-0.9-0.90.71.0-0.8-0.90.70.80.8-1.00.70.7-0.8-0.70.7-0.70.80.7-0.6-0.6-0.4-0.6
Intermittent access total locomotion0.70.81.5-0.8-0.9-0.80.91.2-0.9-0.90.90.90.9-1.20.80.8-0.9-0.80.8-0.80.90.8-0.7-0.7-0.8-0.7
Intermittent access standard deviation0.70.81.3-0.7-0.8-0.80.71.1-1.1-0.81.01.00.9-1.20.90.9-0.7-0.80.9-0.80.90.9-0.7-0.7-0.7-0.8
Left kidney weight3.49.511.43.43.23.2-3.4-3.02.43.2-3.1-3.1-2.52.9-3.2-3.23.23.1-3.13.1-3.0-3.13.13.13.23.0
Right kidney weight1.02.73.61.71.81.7-1.7-1.81.01.8-1.7-1.6-1.21.7-1.7-1.71.91.6-1.71.7-1.7-1.61.61.61.71.5
Cocaine induced anxiety0.10.10.70.80.30.3-0.7-0.10.10.20.0-0.2-0.1-0.1-0.1-0.10.20.1-0.10.1-0.0-0.20.10.10.60.0
Post-drug Anxiety0.10.10.3-0.3-0.4-0.40.30.3-0.0-0.40.40.30.1-0.30.40.4-0.4-0.40.4-0.50.40.5-0.5-0.5-0.3-0.5
Baseline Anxiety2.12.24.4-2.1-1.6-1.62.01.1-1.1-1.51.21.41.1-0.91.51.4-1.5-1.41.4-1.51.31.6-1.6-1.6-2.0-1.4
Tail length16.148.752.15.97.06.9-6.2-6.87.17.0-7.1-7.2-7.16.9-7.2-7.27.17.2-7.27.1-7.1-7.17.27.26.47.0
Length with tail15.657.060.27.27.67.6-7.4-7.57.37.6-7.7-7.6-7.37.5-7.8-7.87.77.6-7.77.6-7.6-7.67.67.67.37.5
Length without tail2.45.38.22.92.32.3-2.8-2.41.92.3-2.4-2.3-1.92.2-2.4-2.42.32.2-2.32.2-2.2-2.32.12.12.42.1
Times rat made contact with spout0.10.20.5-0.7-0.3-0.30.70.4-0.2-0.30.30.40.1-0.40.40.3-0.3-0.30.4-0.30.40.3-0.4-0.4-0.4-0.4
Lifetime Intake0.00.00.20.0-0.00.00.00.4-0.0-0.10.20.20.1-0.40.10.1-0.1-0.10.2-0.10.20.1-0.1-0.10.1-0.1
Liver weight, left0.81.22.60.91.41.4-1.1-1.01.41.6-0.9-0.9-1.31.0-0.9-0.91.11.0-0.81.1-1.0-1.01.11.11.21.0
Liver weight, right3.45.76.91.82.62.5-2.0-2.22.32.6-2.3-2.4-2.42.3-2.4-2.42.62.5-2.32.6-2.4-2.42.62.62.22.5
Locomotor activity1.62.53.1-1.5-1.6-1.61.51.5-1.6-1.51.51.61.6-1.41.71.7-1.5-1.61.7-1.61.51.6-1.6-1.6-1.8-1.6
Locomotor testing distance4.37.19.1-2.9-2.8-2.82.92.5-2.5-2.62.62.72.5-2.42.72.7-2.6-2.62.7-2.72.52.8-2.7-2.7-3.0-2.6
Locomotor testing rearing2.13.35.2-2.3-2.1-2.12.21.5-1.5-2.01.71.71.5-1.41.71.7-1.8-1.71.7-1.81.61.9-1.8-1.8-1.9-1.7
Locomotion in novel chamber0.20.30.6-0.20.60.60.1-0.50.80.7-0.6-0.5-0.80.6-0.5-0.50.70.6-0.50.6-0.6-0.40.60.60.50.5
Locomotion in novel chamber post-restriction3.03.64.4-1.7-1.9-1.91.82.1-1.9-2.01.91.91.9-2.11.91.9-2.0-1.91.8-1.92.01.9-1.8-1.8-1.8-1.8
Fecal boli incidents, locomotor time 11.51.62.8-0.6-1.6-1.60.71.3-1.7-1.41.31.21.5-1.41.31.2-1.2-1.31.2-1.21.31.2-1.3-1.3-0.9-1.1
Change in fecal boli incidents, locomotor task1.61.52.00.81.01.0-0.9-1.31.41.3-1.4-1.2-1.31.4-1.2-1.21.31.2-1.21.3-1.4-1.11.31.31.31.2
Time >=10cm from walls, locomotor time 10.40.40.8-0.8-0.9-0.90.80.8-0.5-0.70.50.50.4-0.80.50.5-0.5-0.40.4-0.50.70.5-0.4-0.4-0.6-0.4
Bouts of movement, locomotor time 10.10.10.20.30.50.4-0.3-0.40.20.3-0.3-0.3-0.20.4-0.4-0.40.40.3-0.20.3-0.4-0.30.30.3-0.00.2
Total resting periods, locomotor time 10.20.20.40.50.60.6-0.5-0.50.30.5-0.4-0.5-0.30.5-0.5-0.50.60.4-0.40.5-0.5-0.50.50.50.10.4
Rest time, locomotor task time 10.00.00.2-0.0-0.0-0.0-0.00.2-0.10.20.1-0.1-0.1-0.20.10.10.40.2-0.10.3-0.1-0.10.30.3-0.50.2
Distance moved, locomotor task time 10.60.71.00.41.01.0-0.5-0.91.00.8-0.9-0.8-0.81.0-1.0-0.90.60.8-0.90.7-0.8-0.90.70.70.80.7
Vertical activity count, locomotor time 10.10.10.20.30.30.3-0.2-0.50.30.2-0.4-0.2-0.20.5-0.4-0.30.10.2-0.20.1-0.3-0.30.20.20.40.1
Time >=10cm from walls, locomotor time 20.10.10.2-0.5-0.2-0.20.4-0.20.20.0-0.2-0.2-0.30.4-0.2-0.20.20.2-0.20.2-0.3-0.00.20.2-0.20.2
Bouts of movement, locomotor time 20.20.20.5-0.6-0.5-0.60.60.2-0.5-0.70.40.40.6-0.10.30.3-0.5-0.40.4-0.50.30.5-0.5-0.5-0.7-0.4
Total resting periods, locomotor time 20.30.30.7-0.6-0.6-0.60.60.4-0.6-0.80.50.50.7-0.40.40.4-0.6-0.50.5-0.60.50.6-0.6-0.6-0.8-0.5
Rest time, locomotor task time 20.00.00.20.4-0.2-0.2-0.30.10.3-0.10.1-0.0-0.3-0.20.10.00.10.00.00.10.0-0.00.20.2-0.20.2
Distance moved, locomotor task time 22.12.43.51.21.91.9-1.3-1.51.41.7-1.6-1.6-1.41.6-1.6-1.61.61.6-1.51.5-1.5-1.61.51.51.41.5
Vertical activity count, locomotor time 21.31.42.30.91.51.5-1.0-1.20.91.4-1.3-1.2-0.91.3-1.3-1.31.31.2-1.21.2-1.3-1.21.21.21.01.1
Light reinforcement 12.13.95.6-2.4-2.0-2.02.31.9-1.8-2.01.91.91.7-1.81.91.9-1.9-1.91.9-1.91.92.1-2.0-2.0-2.1-2.0
Light reinforcement 20.20.30.8-0.9-0.4-0.40.80.6-0.4-0.30.50.60.4-0.50.60.5-0.3-0.50.6-0.50.60.6-0.5-0.5-0.7-0.6
Bone: marrow area0.30.71.61.31.01.0-1.2-1.10.40.9-0.9-0.8-0.41.0-0.8-0.80.80.7-0.80.7-0.8-0.90.60.61.00.7
Bone: maximum diameter0.00.10.2-0.3-0.0-0.00.20.1-0.4-0.00.20.20.3-0.10.10.1-0.2-0.20.2-0.20.20.2-0.4-0.4-0.2-0.3
Bone: maximum force0.10.10.20.00.40.4-0.1-0.4-0.10.4-0.4-0.30.00.4-0.4-0.30.30.3-0.30.3-0.4-0.30.30.20.20.3
Bone: maximum moment0.10.20.40.20.60.5-0.3-0.50.00.6-0.5-0.5-0.10.6-0.6-0.50.50.5-0.60.5-0.5-0.50.40.40.40.5
Mean time between licks in bursts0.00.00.10.4-0.00.0-0.30.0-0.1-0.10.00.10.2-0.10.10.1-0.0-0.10.1-0.10.1-0.0-0.0-0.00.0-0.1
Mean num. licks in bursts0.10.10.10.10.20.2-0.1-0.30.20.1-0.4-0.3-0.10.4-0.3-0.30.10.3-0.40.2-0.3-0.30.20.20.10.3
Cd content in liver0.00.10.10.0-0.0-0.1-0.0-0.10.3-0.1-0.3-0.3-0.10.1-0.4-0.40.10.3-0.30.1-0.2-0.30.30.30.20.3
Co content in liver0.10.20.60.80.30.3-0.7-0.50.20.2-0.4-0.3-0.10.4-0.3-0.30.30.3-0.30.3-0.4-0.40.30.30.60.3
Cu content in liver0.50.61.30.90.90.9-0.9-0.81.10.9-0.6-0.6-1.10.8-0.6-0.60.80.6-0.60.7-0.7-0.70.60.60.70.7
Fe content in liver2.83.43.91.92.02.0-1.9-1.81.91.9-1.7-1.9-1.91.7-1.8-1.91.91.8-1.91.9-1.8-1.91.81.81.71.8
K content in liver0.00.00.0-0.1-0.1-0.10.1-0.2-0.2-0.1-0.00.00.10.20.0-0.00.00.0-0.0-0.0-0.10.00.00.0-0.20.1
Mg content in liver0.10.10.30.00.20.2-0.0-0.30.50.2-0.3-0.3-0.50.3-0.3-0.40.30.3-0.40.3-0.3-0.30.30.30.10.3
Mn content in liver0.00.00.3-0.2-0.1-0.10.2-0.00.5-0.0-0.0-0.1-0.50.10.0-0.00.20.00.00.1-0.00.0-0.0-0.0-0.1-0.0
Na content in liver1.51.61.8-1.0-1.3-1.31.11.3-1.3-1.31.31.31.3-1.31.31.3-1.3-1.31.3-1.31.21.3-1.3-1.3-1.3-1.2
Rb content in liver0.91.12.0-1.4-0.8-0.81.31.3-0.5-0.81.11.00.6-1.21.01.0-0.8-1.01.1-1.01.11.1-1.0-1.0-1.4-1.1
Se content in liver0.20.20.7-0.8-0.5-0.50.80.5-0.5-0.40.40.40.4-0.40.40.3-0.2-0.30.3-0.40.40.5-0.3-0.3-0.6-0.4
Sr content in liver2.62.32.91.41.41.4-1.4-1.71.51.4-1.6-1.6-1.61.7-1.6-1.61.51.6-1.61.5-1.6-1.51.51.51.51.6
Zn content in liver0.70.81.9-1.3-1.1-1.11.20.7-0.7-1.00.80.70.7-0.60.70.7-0.9-0.70.6-0.80.70.9-0.9-0.9-1.4-0.8
Bone: minimum diameter0.61.21.51.11.11.1-1.1-1.20.71.1-1.1-1.1-0.81.2-1.2-1.21.11.1-1.21.1-1.1-1.10.90.91.21.0
Time in familiar zone, hab. session 10.50.50.7-0.8-0.8-0.80.80.8-0.3-0.70.70.60.4-0.80.70.7-0.8-0.60.6-0.60.80.7-0.7-0.7-0.4-0.6
Time in novel zone, hab. session 11.21.12.0-1.0-1.1-1.11.10.9-1.4-1.10.91.11.3-0.91.01.0-1.0-1.01.0-1.10.91.1-1.0-1.0-1.3-1.0
Total zone transitions, hab. session 14.25.88.22.32.42.5-2.4-2.32.92.5-2.4-2.4-2.92.2-2.3-2.32.42.4-2.32.4-2.3-2.42.32.32.42.3
Total locomotion distance, hab. session 11.01.42.50.81.21.2-0.9-0.91.61.2-1.2-1.2-1.61.0-1.2-1.21.31.2-1.11.2-1.1-1.21.21.21.01.2
Locomotion velocity, hab. session 12.53.65.11.62.01.9-1.7-1.72.22.0-1.9-1.9-2.31.7-1.9-1.92.01.9-1.81.9-1.8-1.92.01.91.71.8
Time in familiar zone, hab. session 21.61.71.8-1.3-1.3-1.31.31.3-1.1-1.31.31.31.2-1.31.31.3-1.3-1.31.3-1.31.31.3-1.3-1.3-1.1-1.3
Time in novel zone, hab. session 20.50.50.60.50.70.7-0.5-0.70.50.7-0.8-0.7-0.70.7-0.8-0.80.70.7-0.80.7-0.7-0.70.70.70.40.7
Total zone transitions, hab. session 20.60.81.50.90.90.9-0.9-0.81.20.9-0.9-0.9-1.20.8-0.8-0.80.90.9-0.80.9-0.8-0.90.80.80.90.8
Total locomotion distance, hab. session 20.00.00.00.10.10.1-0.10.00.10.1-0.1-0.1-0.2-0.0-0.1-0.10.10.1-0.10.10.0-0.10.10.1-0.00.0
Locomotion velocity, hab. session 20.20.20.30.50.50.5-0.5-0.40.40.5-0.5-0.4-0.60.3-0.5-0.50.60.5-0.40.5-0.4-0.50.50.50.40.4
Novel to familiar place preference ratio2.82.83.71.91.51.6-1.8-1.91.41.5-1.8-1.7-1.41.9-1.7-1.71.61.7-1.71.6-1.8-1.71.61.61.91.7
Novelty place preference2.82.83.71.71.61.6-1.7-1.91.51.5-1.8-1.7-1.41.9-1.7-1.71.61.7-1.71.7-1.8-1.71.71.61.81.6
Time in novel zone, NPP test1.81.82.51.31.21.2-1.3-1.61.21.2-1.5-1.4-1.21.6-1.4-1.41.31.4-1.41.3-1.4-1.31.31.31.51.3
Total zone transitions, NPP test1.72.54.31.31.61.6-1.4-1.42.01.7-1.5-1.6-2.11.4-1.5-1.51.51.6-1.51.6-1.5-1.51.61.61.41.5
Total locomotion distance, NPP test0.30.40.90.40.60.6-0.4-0.40.90.7-0.6-0.6-0.90.4-0.6-0.60.60.6-0.60.6-0.5-0.60.70.70.50.6
Locomotion velocity, NPP test1.11.62.51.11.31.3-1.2-1.01.51.4-1.2-1.2-1.61.0-1.2-1.21.21.3-1.21.3-1.2-1.21.31.31.11.2
Intraocular pressure2.02.83.91.91.61.6-1.9-1.81.61.5-1.6-1.6-1.51.8-1.5-1.51.51.6-1.61.7-1.8-1.71.81.82.01.7
Delta distance traveled before/after self-admin1.11.22.6-0.2-1.3-1.30.40.6-1.6-1.31.01.11.6-0.71.01.0-1.2-1.21.0-1.10.91.1-1.1-1.1-0.5-1.1
Delta ambulatory time before/after self-admin1.01.02.5-0.4-1.2-1.30.50.6-1.6-1.20.91.01.5-0.71.00.9-1.0-1.11.0-1.00.91.0-1.1-1.1-0.5-1.0
Parametrial fat weight0.10.10.8-0.9-0.2-0.20.80.3-0.3-0.10.20.20.2-0.10.20.1-0.1-0.20.2-0.20.20.3-0.3-0.3-0.8-0.4
Pavlov. Cond. lever latency0.10.10.91.00.10.1-0.8-0.3-0.5-0.0-0.1-0.10.50.1-0.1-0.10.10.0-0.10.1-0.2-0.20.10.10.50.1
Pavlov. Cond. magazine entry latency1.11.55.1-2.3-1.2-1.32.11.2-0.9-1.11.01.00.9-0.91.01.0-1.1-0.90.9-1.01.01.2-1.1-1.1-1.5-1.1
Pavlov. Cond. change in total contacts0.20.21.5-1.2-0.4-0.51.10.50.2-0.30.20.2-0.2-0.20.20.2-0.3-0.10.2-0.20.20.4-0.2-0.2-0.3-0.2
Pavlov. Cond. index score0.81.04.1-2.0-0.9-1.01.81.0-0.4-0.80.80.80.4-0.80.80.8-0.9-0.70.8-0.80.81.0-0.9-0.9-1.3-0.9
Pavlov. Cond. latency score0.40.62.8-1.7-0.7-0.71.50.8-0.2-0.50.60.60.1-0.50.60.6-0.6-0.50.5-0.60.60.7-0.6-0.6-1.0-0.6
Pavlov. Cond. lever contacts0.10.10.8-0.9-0.0-0.10.70.30.50.10.10.1-0.6-0.10.10.1-0.00.00.1-0.00.10.2-0.1-0.1-0.4-0.1
Pavlov. Cond. magazine entry number2.02.67.32.71.71.7-2.5-1.51.11.5-1.4-1.4-1.11.2-1.4-1.41.51.3-1.41.5-1.4-1.61.51.51.81.5
Pavlov. Cond. intertrial magazine entries0.91.11.81.31.11.1-1.3-0.91.01.1-0.9-1.0-1.10.8-1.0-1.01.01.0-0.91.0-0.9-1.11.11.11.01.1
Pavlov. Cond. lever-magazine prob. diff.0.91.14.4-2.1-1.0-1.01.91.1-0.4-0.80.80.80.4-0.80.90.8-0.9-0.70.8-0.80.91.0-0.9-0.9-1.3-0.9
Pavlov. Cond. response bias1.11.45.0-2.2-1.1-1.22.01.2-0.5-1.01.01.00.5-0.91.01.0-1.0-0.91.0-1.01.01.2-1.1-1.1-1.4-1.1
Pavlov. Cond. lever latency0.60.81.00.80.80.8-0.8-0.80.90.9-0.8-1.0-0.90.8-1.0-1.00.80.9-1.00.9-0.8-0.90.80.80.90.9
Pavlov. Cond. magazine entry latency1.01.21.50.91.01.0-0.9-1.21.01.1-1.2-1.1-1.11.2-1.1-1.01.01.1-1.11.1-1.2-1.11.11.11.21.1
Pavlov. Cond. change in total contacts0.30.40.7-0.8-0.6-0.60.70.6-0.6-0.60.60.70.7-0.60.70.7-0.6-0.60.7-0.60.60.7-0.5-0.5-0.8-0.6
Pavlov. Cond. index score0.00.00.1-0.2-0.1-0.10.20.1-0.3-0.10.10.20.2-0.10.20.2-0.1-0.10.2-0.10.10.10.00.0-0.1-0.1
Pavlov. Cond. latency score0.00.10.10.10.30.3-0.1-0.20.10.3-0.3-0.2-0.10.2-0.2-0.20.30.2-0.10.2-0.3-0.20.40.40.30.2
Pavlov. Cond. lever contacts0.60.81.0-1.0-0.9-0.91.01.0-0.9-0.90.81.01.0-0.91.01.0-0.8-0.91.0-0.90.90.9-0.7-0.7-1.0-0.9
Pavlov. Cond. magazine entry number0.20.30.4-0.2-0.6-0.60.30.5-0.4-0.70.60.50.5-0.60.40.4-0.5-0.50.4-0.60.60.6-0.7-0.7-0.4-0.6
Pavlov. Cond. intertrial magazine entries0.60.71.31.00.80.8-1.0-0.81.20.8-0.8-0.9-1.10.7-0.9-0.90.80.8-0.90.8-0.7-0.80.70.70.90.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.1-0.0-0.00.10.0-0.2-0.00.00.20.2-0.00.10.2-0.0-0.10.2-0.10.00.00.10.1-0.0-0.0
Pavlov. Cond. response bias0.40.50.8-0.9-0.7-0.70.90.7-0.8-0.70.60.80.7-0.60.70.7-0.6-0.70.8-0.70.60.7-0.5-0.5-0.8-0.7
Time in closed arm before self-admin0.91.02.1-1.3-1.0-1.01.30.9-1.0-1.00.91.00.9-0.80.90.9-1.0-1.00.9-1.00.91.1-1.0-1.0-1.5-1.0
Time in closed arm after self-admin0.00.00.10.2-0.2-0.2-0.20.1-0.3-0.10.10.10.2-0.20.10.1-0.1-0.20.2-0.10.10.1-0.1-0.1-0.0-0.1
Time in open arm before self-admin0.10.10.80.90.20.2-0.7-0.50.20.2-0.3-0.2-0.20.3-0.2-0.20.30.2-0.10.3-0.2-0.40.30.30.80.4
Time in open arm after self-admin0.10.20.4-0.2-0.2-0.30.20.5-0.0-0.40.50.40.2-0.60.50.5-0.4-0.40.4-0.40.50.4-0.4-0.4-0.3-0.4
Bone: periosteal estimation0.10.20.30.40.60.6-0.4-0.60.10.5-0.4-0.4-0.10.5-0.5-0.50.40.4-0.50.4-0.4-0.40.20.20.40.3
Bone: periosteal perimeter0.10.20.40.60.60.6-0.6-0.50.10.5-0.4-0.4-0.20.5-0.5-0.50.50.4-0.40.4-0.4-0.50.30.30.50.4
Bone: post-yield work0.20.30.50.70.50.5-0.7-0.70.20.5-0.5-0.4-0.10.6-0.5-0.50.40.4-0.50.5-0.5-0.50.40.40.70.5
Progressive ratio test 1 active lever presses0.10.10.3-0.00.20.3-0.0-0.10.20.2-0.4-0.3-0.20.2-0.4-0.40.30.5-0.40.4-0.4-0.40.50.50.10.5
Progressive ratio test 1 breakpoint0.30.30.50.10.40.4-0.1-0.30.40.4-0.6-0.5-0.50.4-0.6-0.60.50.7-0.60.6-0.6-0.60.70.70.20.7
Progressive ratio test 1 inactive lever presses0.30.40.9-0.9-0.4-0.40.81.0-0.4-0.40.70.60.4-0.90.60.6-0.4-0.50.6-0.50.60.5-0.5-0.5-0.9-0.4
Progressive ratio test 2 active lever presses0.20.20.4-0.7-0.5-0.40.60.6-0.3-0.50.40.50.3-0.60.40.4-0.4-0.40.4-0.40.40.4-0.4-0.4-0.5-0.4
Progressive ratio test 2 breakpoint0.20.20.3-0.6-0.4-0.40.60.5-0.3-0.40.40.50.3-0.50.40.4-0.4-0.40.4-0.40.40.4-0.3-0.3-0.3-0.4
Progressive ratio test 2 inactive lever presses0.20.20.7-0.3-0.5-0.50.30.8-0.2-0.50.60.50.3-0.80.50.5-0.4-0.40.5-0.40.60.4-0.5-0.5-0.3-0.4
Incentive Sensitization - Responses0.30.40.6-0.8-0.5-0.50.80.7-0.4-0.50.60.60.4-0.60.60.6-0.5-0.60.6-0.60.60.6-0.6-0.6-0.6-0.7
Incentive Sensitization - Breakpoint0.40.40.6-0.8-0.5-0.50.70.7-0.5-0.50.60.60.4-0.70.60.6-0.5-0.60.6-0.60.60.6-0.7-0.7-0.6-0.7
Sum of active levers in priming session hrs 5-61.31.32.00.71.01.0-0.8-1.21.41.0-1.2-1.1-1.31.3-1.1-1.11.11.1-1.11.1-1.2-1.01.11.11.31.1
Progressive ratio0.10.10.40.10.40.4-0.2-0.00.60.4-0.2-0.4-0.50.1-0.4-0.40.40.5-0.40.4-0.2-0.40.50.50.20.4
Food seeking constrained by brief footshock0.30.40.6-0.8-0.6-0.70.70.7-0.8-0.70.50.60.8-0.70.50.5-0.6-0.60.5-0.70.70.5-0.6-0.6-0.7-0.6
Seeking ratio, punishment vs. effort0.10.10.4-0.4-0.4-0.40.40.1-0.7-0.40.10.40.6-0.20.30.3-0.4-0.40.4-0.40.30.3-0.4-0.4-0.3-0.4
Retroperitoneal fat weight0.31.12.10.81.41.4-0.9-1.10.61.5-1.0-1.0-0.81.1-1.2-1.21.31.0-1.01.1-1.1-1.10.80.80.60.9
Reaction time number correct0.10.20.30.60.50.5-0.5-0.60.60.4-0.4-0.5-0.60.6-0.4-0.40.40.4-0.50.4-0.5-0.40.40.40.30.4
Reaction time mean minus median0.20.20.4-0.6-0.4-0.40.50.6-0.2-0.40.50.50.2-0.60.50.5-0.5-0.50.5-0.50.60.4-0.5-0.5-0.5-0.6
Reaction time mean minus median AUC0.60.81.3-1.2-0.9-0.91.11.1-0.5-0.90.90.90.5-1.00.90.9-0.8-0.90.9-0.91.00.9-0.8-0.8-1.1-1.0
Reaction time num false alarms0.10.10.3-0.5-0.5-0.50.5-0.3-0.1-0.5-0.2-0.10.00.4-0.1-0.1-0.20.1-0.2-0.1-0.10.1-0.2-0.2-0.2-0.1
Reaction time num false alarms AUC0.10.10.3-0.3-0.2-0.30.3-0.50.1-0.3-0.4-0.3-0.20.6-0.3-0.3-0.00.3-0.40.1-0.3-0.10.10.1-0.10.1
Reaction time trials correct on left0.10.20.30.60.50.5-0.5-0.60.60.4-0.4-0.5-0.60.6-0.4-0.40.40.4-0.50.4-0.5-0.40.40.40.30.4
Reaction time trials on left0.10.20.30.50.50.5-0.5-0.60.60.4-0.4-0.5-0.50.5-0.4-0.40.40.4-0.50.4-0.5-0.40.40.40.30.3
Reaction time mean1.11.62.0-1.1-1.2-1.21.21.4-1.1-1.21.31.31.1-1.41.31.3-1.3-1.31.3-1.31.41.2-1.3-1.3-1.1-1.4
Reaction time mean AUC1.01.41.8-1.0-1.1-1.01.11.3-1.0-1.11.21.21.0-1.31.21.2-1.1-1.31.3-1.21.31.0-1.1-1.1-1.1-1.3
Median of all reaction times1.82.42.9-1.4-1.5-1.51.51.7-1.4-1.61.61.61.4-1.71.61.6-1.6-1.61.6-1.61.71.5-1.6-1.6-1.4-1.7
Reaction time omissions0.10.20.6-0.7-0.4-0.40.70.2-0.4-0.40.20.40.4-0.10.40.4-0.3-0.40.4-0.40.30.3-0.3-0.3-0.5-0.4
Reaction time false alarm rate0.10.10.4-0.6-0.5-0.60.6-0.1-0.3-0.5-0.00.10.20.2-0.0-0.0-0.3-0.1-0.1-0.20.00.2-0.2-0.2-0.3-0.1
Reaction time premature initiation rate0.20.20.50.00.50.5-0.1-0.20.60.4-0.4-0.6-0.60.3-0.5-0.50.60.7-0.60.7-0.5-0.40.60.60.20.6
Reaction time premature initiations0.50.60.90.50.80.8-0.6-0.70.90.7-0.7-0.9-1.00.7-0.8-0.80.81.0-0.90.9-0.8-0.70.90.90.50.9
Std. dev. reaction times0.20.20.3-0.6-0.5-0.40.60.6-0.3-0.50.40.40.3-0.60.50.5-0.4-0.50.4-0.50.60.4-0.4-0.4-0.5-0.6
Reaction time trials completed0.10.20.30.50.50.5-0.5-0.60.60.4-0.4-0.5-0.50.5-0.4-0.40.40.4-0.50.4-0.5-0.40.40.40.30.3
Reaction time trials AUC0.10.20.30.50.40.4-0.4-0.50.50.3-0.3-0.4-0.50.5-0.3-0.30.30.4-0.40.3-0.4-0.40.30.30.20.3
Run reversals in cocaine runway, females1.71.72.51.61.11.2-1.5-1.61.01.0-1.3-1.4-0.81.5-1.3-1.31.01.3-1.31.2-1.4-1.31.31.31.51.4
Run reversals in cocaine runway, males4.94.85.5-2.1-2.1-2.12.12.0-1.8-2.12.32.31.9-2.02.32.3-2.3-2.32.3-2.22.22.3-2.4-2.4-2.1-2.4
Latency to leave start box in cocaine runway0.50.61.30.2-0.9-0.8-0.00.8-1.1-0.90.80.71.1-1.00.60.6-0.8-0.80.6-0.80.90.6-0.8-0.8-0.5-0.7
Latency to leave start box in cocaine runway, F0.70.71.80.0-0.9-0.90.11.1-1.3-0.90.90.81.2-1.30.80.8-0.8-0.80.7-0.81.00.7-0.8-0.8-0.6-0.8
Latency to leave start box in cocaine runway, M0.20.20.50.1-0.4-0.40.10.3-0.5-0.50.50.40.7-0.40.40.4-0.4-0.50.4-0.50.50.3-0.5-0.5-0.1-0.5
Std. dev. time between licks in bursts0.70.91.3-0.5-0.9-0.90.60.9-1.1-1.01.00.91.2-1.00.90.9-1.0-1.00.9-1.01.00.9-1.0-1.0-0.7-1.0
Total sessions with >9 infusions0.30.30.8-0.6-0.5-0.40.60.9-0.6-0.50.60.50.6-0.90.50.5-0.4-0.40.5-0.40.60.4-0.3-0.3-0.4-0.3
Short access day 1 total inactive lever presses0.10.11.0-0.40.40.40.30.21.00.3-0.1-0.1-0.8-0.0-0.1-0.10.30.2-0.10.2-0.1-0.10.20.2-0.10.2
Short access day 10 total inactive lever presses0.00.00.20.10.0-0.0-0.10.20.4-0.10.10.1-0.3-0.20.10.1-0.1-0.10.2-0.10.20.0-0.1-0.1-0.3-0.2
Short access day 1 total infusions0.20.20.6-0.4-0.3-0.20.40.8-0.2-0.30.60.50.2-0.80.50.5-0.3-0.40.5-0.40.60.4-0.4-0.4-0.3-0.4
Short access day 10 total infusions0.10.10.3-0.1-0.4-0.40.10.5-0.5-0.40.40.50.5-0.50.40.4-0.4-0.40.4-0.30.40.3-0.3-0.30.1-0.2
Short access total infusions0.00.00.10.10.10.1-0.10.3-0.00.00.10.10.0-0.30.00.00.10.00.00.10.1-0.00.00.00.20.1
Short access day 1 locomotion0.70.71.6-1.2-0.5-0.51.11.3-0.7-0.51.01.00.7-1.20.90.9-0.6-0.81.0-0.70.90.8-0.7-0.7-0.8-0.7
Short access day 10 total locomotion0.30.40.8-0.8-0.8-0.80.70.7-0.8-0.90.40.60.7-0.60.50.5-0.8-0.50.5-0.50.50.7-0.3-0.3-0.6-0.2
Short access total locomotion0.30.30.7-0.6-0.5-0.50.60.8-0.7-0.50.60.60.6-0.80.40.5-0.5-0.40.5-0.40.50.5-0.3-0.3-0.5-0.3
One hour access (0.3 mA shock)0.00.00.20.10.10.2-0.0-0.00.40.0-0.2-0.2-0.20.1-0.2-0.2-0.00.2-0.20.1-0.1-0.20.10.10.10.2
Compulsive drug intake3.63.66.21.22.22.2-1.4-1.82.52.1-1.9-1.9-2.22.0-1.9-1.82.01.9-1.81.9-1.9-2.01.81.81.41.8
One hour access (shock baseline)1.92.22.9-1.2-1.5-1.51.31.5-1.7-1.61.51.51.7-1.51.41.4-1.6-1.51.4-1.51.51.5-1.5-1.5-1.4-1.5
Social response proportion1.92.13.10.81.31.2-0.9-1.51.21.2-1.8-1.7-1.31.7-1.7-1.71.41.6-1.71.5-1.6-1.51.61.60.81.5
Social responses0.10.10.4-0.00.10.10.0-0.50.10.0-0.4-0.5-0.20.6-0.5-0.50.20.4-0.60.3-0.4-0.40.30.30.10.3
Social time0.60.81.5-0.8-1.1-1.10.90.6-0.8-1.20.90.80.9-0.60.80.8-1.0-0.90.8-0.90.80.9-1.1-1.1-0.8-1.0
Soleus weight0.20.61.3-1.1-0.6-0.71.10.7-1.1-0.60.60.80.9-0.60.70.7-0.7-0.80.8-0.70.70.7-0.7-0.7-1.1-0.8
Bone: stiffness0.10.20.60.10.40.4-0.2-0.70.20.5-0.6-0.5-0.30.8-0.6-0.60.40.5-0.60.5-0.6-0.40.40.40.40.4
Tibialis anterior weight0.62.13.21.81.61.7-1.7-1.41.51.6-1.4-1.3-1.51.3-1.3-1.21.41.2-1.21.3-1.3-1.41.31.31.71.2
Time to tail flick, vehicle, before self-admin0.20.20.60.40.40.4-0.4-0.40.80.4-0.4-0.5-0.50.5-0.5-0.50.30.5-0.60.4-0.5-0.50.30.30.80.6
Time to tail flick, vehicle, after self-admin0.30.30.6-0.6-0.5-0.50.60.8-0.5-0.50.80.60.5-0.80.70.7-0.5-0.60.7-0.50.70.5-0.5-0.5-0.3-0.6
Time to tail flick, test, before self-admin0.00.00.10.20.10.0-0.2-0.0-0.0-0.00.00.10.1-0.10.10.1-0.2-0.20.1-0.20.10.1-0.1-0.10.2-0.2
Time to tail flick, test, after self-admin0.10.10.30.40.30.3-0.3-0.30.10.3-0.3-0.3-0.00.2-0.3-0.30.20.3-0.30.3-0.3-0.30.30.30.50.4
Delta time to tail flick, vehicle, before/after SA0.80.81.3-1.0-0.7-0.71.01.0-0.9-0.71.00.90.8-1.01.01.0-0.7-0.91.1-0.81.00.9-0.7-0.7-1.0-1.0
Delta time to tail flick, test, before/after SA0.60.51.00.20.70.7-0.3-0.50.60.8-0.7-0.7-0.60.7-0.7-0.70.80.9-0.80.9-0.8-0.70.80.80.51.0
Tibia length0.30.81.61.31.11.1-1.2-1.00.41.0-0.8-0.9-0.50.9-0.9-0.90.80.8-0.90.9-0.9-0.90.80.81.10.7
Ambulatory time before self-admin0.40.40.70.40.60.6-0.5-0.70.70.7-0.7-0.6-0.90.7-0.5-0.50.60.6-0.60.6-0.6-0.60.70.70.20.6
Ambulatory time after self-admin0.20.20.80.9-0.2-0.2-0.7-0.7-0.6-0.0-0.4-0.10.40.5-0.2-0.20.20.1-0.30.2-0.4-0.20.20.20.60.3
Bone: tissue strength0.10.10.20.2-0.3-0.2-0.10.1-0.3-0.30.20.20.4-0.20.20.2-0.3-0.20.2-0.30.20.1-0.2-0.20.2-0.2
Total heroin consumption0.10.10.50.10.30.3-0.1-0.40.70.3-0.3-0.2-0.60.4-0.2-0.20.20.2-0.10.2-0.3-0.20.20.20.30.1
Bone: trabecular number1.72.64.9-2.2-1.4-1.52.11.7-1.4-1.41.71.61.4-1.51.61.6-1.5-1.51.6-1.51.51.7-1.6-1.6-1.8-1.6
Bone: trabecular spacing0.10.10.20.1-0.4-0.4-0.00.2-0.2-0.40.20.20.2-0.30.20.2-0.3-0.20.2-0.30.30.3-0.2-0.2-0.1-0.2
Bone: trabecular thickness0.00.00.10.10.20.2-0.1-0.0-0.40.10.1-0.00.40.1-0.0-0.0-0.10.0-0.10.0-0.1-0.10.00.0-0.00.0
Bone: trabecular tissue density0.00.10.10.10.20.2-0.1-0.20.30.2-0.2-0.2-0.40.2-0.2-0.20.20.3-0.20.3-0.2-0.20.30.30.10.3
Water consumed over 24 hours0.00.00.1-0.20.00.00.20.10.2-0.00.20.2-0.1-0.10.20.20.0-0.20.2-0.10.10.1-0.1-0.1-0.2-0.2
Number of responses in last shaping day0.40.41.2-0.3-0.8-0.70.31.0-0.6-0.70.80.60.5-1.10.70.7-0.6-0.60.6-0.50.80.6-0.5-0.5-0.1-0.5