Hub : Genes

Mri1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Mri1 0.11 0.05 7.6e-10 0.09 0.08 0.09 0.09 2.4e-10 2.3e-09 3.6e-10 8.8e-10
2 BLA gene expression Mri1 0.27 0.1 2.0e-09 0.15 0.15 0.13 0.16 3.4e-08 3.2e-08 2.8e-07 1.3e-08
3 NAcc gene expression Mri1 0.19 0.07 0.0e+00 0.14 0.17 0.17 0.18 8.1e-21 3.6e-25 3.8e-25 4.3e-27
4 IL gene expression Mri1 0.2 0.1 1.5e-03 0.12 0.09 0.08 0.09 8.7e-04 3.3e-03 7.1e-03 3.5e-03
5 IC gene expression Mri1 0.19 0.1 8.6e-05 0.09 0.09 0.11 0.09 1.0e-04 1.2e-04 3.3e-05 1.5e-04
6 Brain gene expression Mri1 0.53 0.12 0.0e+00 0.45 0.47 0.49 0.47 7.6e-46 4.6e-49 2.9e-51 2.1e-49
7 IC mRNA stability Mri1 0.15 0.08 3.5e-06 0.11 0.14 0.14 0.13 2.6e-05 2.8e-06 1.7e-06 3.2e-06
8 OFC gene expression Mri1 0.3 0.13 2.3e-04 0.1 0.04 0.03 0.04 2.1e-03 4.9e-02 6.0e-02 3.2e-02
9 pVTA mRNA stability Mri1 0.07 0.04 6.9e-06 0.04 0.05 0.06 0.05 7.7e-04 5.3e-05 2.2e-05 1.3e-04
10 pVTA gene expression Mri1 0.15 0.07 5.9e-09 0.12 0.11 0.11 0.11 4.9e-10 2.8e-09 7.6e-09 2.1e-09
11 OFC mRNA stability Mri1 0.51 0.23 4.1e-05 0.16 0.11 0.14 0.17 1.2e-04 1.4e-03 3.3e-04 7.8e-05
12 Liver gene expression Mri1 0.1 0.05 3.5e-08 0.05 0.06 0.06 0.05 4.9e-06 6.6e-07 1.0e-06 1.8e-06
13 Eye mRNA stability Mri1 0.49 0.18 1.6e-05 0.32 0.13 0.22 0.24 8.5e-06 4.4e-03 2.6e-04 1.2e-04
14 Brain mRNA stability Mri1 0.4 0.11 0.0e+00 0.4 0.47 0.47 0.47 3.3e-39 2.2e-48 2.2e-48 3.6e-49
15 PL mRNA stability Mri1 0.26 0.09 0.0e+00 0.24 0.25 0.24 0.26 3.0e-26 1.3e-27 1.9e-26 1.3e-28
16 Adipose mRNA stability Mri1 0.06 0.03 2.5e-07 0.05 0.05 0.05 0.06 7.0e-06 2.5e-06 2.7e-06 9.5e-07
17 NAcc mRNA stability Mri1 0.14 0.06 0.0e+00 0.15 0.16 0.16 0.16 3.1e-22 9.2e-23 1.9e-23 3.5e-24
18 BLA mRNA stability Mri1 0.25 0.09 2.9e-13 0.24 0.25 0.25 0.26 4.2e-13 1.4e-13 2.7e-13 9.0e-14
19 LHb mRNA stability Mri1 0.22 0.12 2.0e-03 0.01 0.01 0.03 0.02 1.8e-01 1.5e-01 6.9e-02 1.3e-01
20 Liver mRNA stability Mri1 0.23 0.09 0.0e+00 0.23 0.22 0.23 0.23 1.0e-25 4.8e-24 5.3e-25 3.5e-25
21 Adipose gene expression Mri1 0.33 0.1 0.0e+00 0.29 0.31 0.31 0.31 3.3e-32 5.0e-35 9.3e-35 4.5e-35

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density2.13.79.53.12.52.02.01.62.7-2.31.9-2.10.9-1.40.3-2.3-1.8-2.0-1.8-1.7-1.9-1.7-1.5-0.9
Area under the delay curve0.20.30.7-0.5-0.4-0.6-0.4-0.60.1-0.1-0.2-0.2-0.9-0.6-0.9-0.80.0-0.1-0.8-0.2-0.60.2-0.3-0.6
BMI with tail2.27.620.6-3.1-2.9-2.3-2.7-3.3-2.52.4-3.53.2-0.54.50.13.62.72.64.02.71.8-0.41.92.0
BMI without tail0.20.52.8-0.5-0.4-0.5-0.5-1.30.1-0.1-0.90.2-0.61.7-0.40.20.30.01.30.1-0.5-0.9-0.2-0.1
Body weight0.10.42.7-0.6-0.10.30.50.2-0.2-0.0-0.10.40.30.90.91.2-0.00.01.60.00.1-1.00.10.4
Weight adjusted by age0.30.52.1-0.9-0.9-0.6-0.9-0.4-0.80.7-0.30.6-0.4-0.6-0.5-0.70.40.7-0.60.60.51.50.40.2
Bone surface2.85.28.32.62.31.42.01.52.7-2.71.9-2.8-0.5-1.8-0.8-2.9-2.7-2.7-2.3-2.6-2.5-2.2-2.6-2.2
Bone volume3.05.39.12.92.51.72.21.82.8-2.72.0-2.8-0.1-1.7-0.5-3.0-2.6-2.7-2.2-2.5-2.3-2.4-2.4-2.0
Breakpoint value in progressive ratio session1.31.55.30.00.11.10.21.0-0.50.50.11.12.30.92.31.40.81.02.01.01.50.31.61.9
Number of licking bursts0.20.30.70.50.70.90.80.30.7-0.70.7-0.30.8-0.00.80.3-0.1-0.40.6-0.2-0.6-0.4-0.10.1
Context. condit. distance diff. score0.50.62.6-1.6-1.0-0.7-0.8-0.5-1.20.9-0.40.9-0.30.30.00.71.00.91.10.60.60.00.80.4
Locomotion velocity, session 11.01.12.91.41.31.11.50.91.4-1.30.7-1.10.40.00.4-0.5-1.2-1.2-0.2-1.1-0.9-1.7-1.0-0.6
Locomotion distance, session 10.40.41.60.70.81.00.90.50.7-0.70.2-0.11.20.51.30.7-0.3-0.50.8-0.2-0.3-0.3-0.00.4
Locomotion velocity, session 20.50.51.40.91.00.81.20.61.0-0.91.0-0.70.6-0.70.5-0.5-0.5-0.7-0.4-0.6-0.8-0.4-0.5-0.2
Locomotion distance, session 20.40.62.7-0.00.20.80.60.30.0-0.1-0.00.51.40.71.61.40.30.21.60.40.30.10.50.8
Locomotion velocity, session 30.10.10.5-0.2-0.3-0.5-0.2-0.5-0.10.0-0.4-0.2-0.70.3-0.7-0.4-0.2-0.1-0.2-0.2-0.20.5-0.4-0.5
Locomotion distance, session 31.71.94.10.40.70.00.8-0.11.3-1.50.9-1.7-1.4-1.3-1.4-1.6-1.4-1.6-1.5-1.7-2.0-0.2-2.0-2.0
Stereotopy head waving bouts, day 30.91.14.8-0.9-1.0-1.7-1.0-1.5-0.50.3-1.1-0.2-2.20.4-2.1-0.7-0.0-0.1-0.6-0.3-0.4-0.9-0.7-1.2
Stereotopy head waving duration, day 30.50.51.8-0.8-0.9-1.2-0.9-1.3-0.60.5-1.10.4-1.20.7-1.10.00.50.30.10.30.0-0.4-0.0-0.3
Locomotion velocity, session 70.10.10.5-0.7-0.3-0.3-0.1-0.4-0.1-0.1-0.1-0.1-0.50.2-0.30.20.0-0.10.5-0.3-0.3-0.6-0.4-0.5
Locomotion distance, session 70.20.20.90.40.50.80.80.60.5-0.50.5-0.30.9-0.00.90.1-0.3-0.30.6-0.3-0.20.3-0.10.1
Stereotopy head waving bouts, day 71.41.64.60.10.2-0.70.2-0.60.7-0.90.3-1.4-1.8-1.2-1.9-2.2-0.8-1.2-1.8-1.3-1.6-0.9-1.4-1.9
Stereotopy head waving duration, day 71.31.64.10.70.7-0.20.6-0.21.2-1.20.7-1.5-1.3-1.2-1.5-2.0-1.0-1.4-1.7-1.4-1.7-1.3-1.5-1.7
Locomotion velocity, session 80.20.31.1-0.00.40.70.81.00.1-0.20.6-0.00.7-0.01.00.5-0.3-0.21.1-0.30.2-0.5-0.00.2
Locomotion distance, session 80.40.53.0-0.7-0.10.50.30.2-0.40.20.10.71.00.51.31.30.70.41.70.40.30.00.70.7
Degree of sensitization distance1.31.33.8-0.1-0.20.7-0.10.7-0.70.8-0.21.21.80.91.91.50.81.11.71.11.50.41.51.7
Degree of sensitization stereotypy0.80.82.70.00.1-0.60.1-0.60.6-0.60.2-1.1-1.2-0.8-1.3-1.6-0.5-0.9-1.3-0.9-1.2-0.4-1.0-1.4
Conditioned locomotion0.10.10.40.20.40.60.30.60.3-0.40.4-0.20.4-0.30.50.1-0.4-0.30.1-0.3-0.1-0.1-0.20.0
Cocaine response after cond. corrected0.80.93.7-0.7-0.40.4-0.40.3-0.80.7-0.31.21.10.81.41.50.80.91.90.91.1-0.31.11.3
Cocaine response after cond. not corrected1.01.24.7-0.5-0.20.6-0.20.5-0.80.7-0.11.31.50.91.71.60.91.12.21.01.3-0.31.31.6
Cocaine response before conditioning0.20.30.60.70.60.40.60.30.8-0.60.6-0.60.1-0.4-0.0-0.7-0.5-0.6-0.5-0.5-0.7-0.3-0.5-0.4
Saline control response1.52.06.51.61.82.51.91.91.5-1.41.6-0.52.5-0.72.50.6-0.8-0.80.4-0.5-0.60.7-0.10.8
Bone: connectivity density3.96.111.53.42.92.02.51.53.4-3.02.3-2.90.3-2.0-0.3-2.9-2.5-2.7-2.6-2.4-2.8-2.2-2.3-1.8
Bone: cortical apparent density0.30.52.8-0.7-0.7-1.0-0.6-1.7-0.20.2-0.70.2-1.00.5-1.10.40.60.3-0.20.3-0.5-0.4-0.0-0.4
Bone: cortical area0.20.40.90.20.60.90.80.90.5-0.70.6-0.50.6-0.30.8-0.1-0.7-0.70.4-0.7-0.50.2-0.5-0.3
Bone: cortical porosity0.60.75.4-1.0-0.8-0.5-0.60.1-1.10.8-0.40.70.1-0.10.30.80.60.80.20.61.12.30.70.5
Bone: cortical porosity0.30.44.8-0.9-0.5-0.4-0.30.3-0.70.4-0.10.2-0.3-0.7-0.10.3-0.00.2-0.3-0.00.52.20.1-0.1
Bone: cortical thickness0.50.92.4-1.6-1.1-0.4-0.7-0.8-1.10.8-0.91.00.11.00.51.21.00.81.50.80.61.30.70.6
Bone: cortical thickness2.93.58.9-0.4-0.50.9-0.5-0.5-0.71.2-0.72.12.81.72.62.32.21.92.32.31.52.12.53.0
Bone: cortical tissue density0.30.42.7-0.7-0.6-1.0-0.5-1.6-0.10.1-0.60.1-1.10.3-1.20.30.50.1-0.30.1-0.7-0.5-0.2-0.6
Condit. Reinf. active minus inactive responses1.31.45.1-1.6-0.8-1.1-0.3-1.2-0.1-0.50.0-0.8-2.3-1.2-1.9-0.7-0.5-0.7-1.0-1.1-1.41.0-1.5-2.0
Condit. Reinf. active-inactive response ratio0.50.53.3-1.7-0.9-0.6-0.5-0.8-0.60.2-0.10.2-0.9-0.7-0.50.30.30.20.0-0.1-0.31.8-0.2-0.6
Condit. Reinf. active responses1.11.44.1-0.9-0.3-0.8-0.0-0.90.4-0.80.3-1.1-2.0-1.4-1.8-1.1-0.8-1.0-1.5-1.3-1.60.4-1.6-2.0
Condit. Reinf. inactive responses1.82.23.61.61.50.91.40.91.8-1.71.3-1.8-0.4-1.6-0.6-1.6-1.8-1.7-1.9-1.6-1.7-1.1-1.7-1.5
Incentive salience index mean2.12.57.1-0.30.2-0.40.6-0.51.0-1.40.7-1.8-2.2-1.7-2.1-1.7-1.5-1.7-1.9-2.0-2.20.1-2.3-2.7
Condit. Reinf. lever presses2.53.67.31.01.10.21.20.31.7-1.91.2-2.3-1.7-1.9-1.8-2.3-2.1-2.2-2.4-2.4-2.4-1.3-2.5-2.7
Condit. Reinf. active minus inactive responses0.30.41.00.40.50.10.50.30.5-0.70.2-0.9-0.5-0.2-0.4-0.5-0.9-0.9-0.4-1.0-0.7-0.3-0.9-1.0
Condit. Reinf. active-inactive response ratio0.10.10.4-0.2-0.2-0.2-0.30.1-0.40.2-0.20.1-0.10.1-0.00.30.10.20.20.00.40.70.3-0.0
Condit. Reinf. active responses0.10.10.30.40.40.40.40.30.4-0.4-0.1-0.40.20.40.30.1-0.4-0.50.2-0.4-0.3-0.1-0.3-0.2
Condit. Reinf. inactive responses0.30.41.3-0.0-0.20.3-0.2-0.1-0.30.4-0.70.60.91.11.00.80.50.50.90.70.70.60.71.0
Condit. Reinf. lever presses0.10.10.4-0.1-0.3-0.5-0.4-0.5-0.20.2-0.50.1-0.30.6-0.3-0.10.30.10.20.10.2-0.60.2-0.0
Condit. Reinf. lever reinforcers received0.00.00.10.30.20.10.20.10.2-0.3-0.2-0.30.10.40.1-0.1-0.2-0.40.0-0.3-0.1-0.0-0.2-0.2
Conditioned reinforcement - actives0.00.00.10.20.20.30.20.30.1-0.10.2-0.10.20.00.20.1-0.1-0.10.0-0.10.0-0.20.00.0
Conditioned reinforcement - inactives0.00.10.50.10.0-0.20.00.0-0.20.20.0-0.3-0.4-0.3-0.4-0.70.1-0.2-0.4-0.2-0.0-0.2-0.0-0.4
Conditioned locomotion0.20.21.8-0.0-0.0-0.30.1-0.40.00.0-0.4-0.1-0.70.8-0.50.50.0-0.30.3-0.2-0.3-1.4-0.3-0.4
Patch foraging indifference point 0 sec0.20.41.7-0.5-0.1-0.3-0.2-0.10.3-0.7-0.1-0.6-0.8-0.3-0.8-0.3-0.9-0.7-0.4-0.9-0.70.6-1.3-1.1
Patch foraging indifference point AUC0.81.13.01.71.51.61.71.41.3-1.11.2-0.81.3-0.41.1-0.2-0.8-0.8-0.2-0.6-0.4-1.0-0.20.1
Delay disc. indifference point, 0s delay0.80.93.90.90.90.50.80.51.3-1.30.6-0.9-0.4-0.4-0.3-0.8-1.2-1.1-0.3-1.1-1.1-2.0-1.0-0.7
Delay disc. indifference point, 16s delay0.91.02.0-1.2-1.0-0.6-1.0-0.6-1.11.1-0.81.30.11.00.31.01.41.11.01.11.01.11.31.0
Delay disc. indifference point, 2s delay0.40.51.3-0.8-0.9-1.1-1.0-1.0-0.60.6-0.60.2-0.9-0.4-1.2-0.60.40.5-0.90.20.10.5-0.1-0.3
Delay disc. indifference point, 24s delay0.20.21.2-1.1-0.6-0.5-0.4-0.2-0.50.3-0.00.0-0.7-0.7-0.5-0.20.20.2-0.3-0.20.00.4-0.1-0.5
Delay disc. indifference point, 4s delay0.90.92.90.80.5-0.20.3-0.41.1-0.90.3-1.0-0.9-0.9-1.2-1.4-0.8-0.8-1.7-0.9-1.4-0.2-1.1-1.1
Delay disc. indifference point, 8s delay0.30.41.3-1.0-0.7-0.9-0.5-1.00.0-0.1-0.5-0.1-1.2-0.3-0.9-0.70.0-0.2-0.5-0.1-0.70.2-0.3-0.7
Indifference point function ln k0.91.65.3-2.1-1.6-2.1-1.7-2.1-1.00.7-1.60.5-2.30.7-2.10.00.40.3-0.10.1-0.2-0.1-0.5-1.0
Indifference point function log k0.91.65.3-2.1-1.6-2.1-1.7-2.1-1.00.7-1.60.5-2.30.7-2.10.00.40.3-0.10.1-0.2-0.1-0.5-1.0
Patch foraging total patch changes 0 sec0.20.30.8-0.8-0.5-0.6-0.5-0.5-0.1-0.2-0.6-0.2-0.80.1-0.70.2-0.5-0.30.0-0.4-0.30.9-0.9-0.8
Patch foraging total patch changes 12 sec1.41.83.91.31.71.52.01.41.7-1.81.5-1.50.7-1.20.7-0.5-1.5-1.6-0.4-1.5-1.5-0.1-1.4-0.9
Patch foraging total patch changes 18 sec1.82.75.12.32.32.12.21.72.3-2.21.6-1.81.2-1.01.1-0.7-1.8-1.9-0.6-1.7-1.5-0.3-1.3-0.7
Patch foraging total patch changes 24 sec1.32.23.51.61.71.41.71.51.8-1.91.6-1.80.2-1.40.0-1.1-1.8-1.8-1.2-1.7-1.7-0.5-1.8-1.3
Patch foraging total patch changes 6 sec0.30.40.80.80.80.90.80.60.9-0.90.5-0.50.7-0.30.6-0.2-0.6-0.6-0.4-0.5-0.40.6-0.4-0.1
Patch foraging time to switch 0 sec0.10.20.60.40.40.60.50.60.3-0.20.6-0.20.7-0.70.6-0.2-0.1-0.1-0.2-0.1-0.20.80.20.2
Patch foraging water rate 0 sec0.10.21.0-0.3-0.3-0.2-0.5-0.2-0.30.3-0.70.40.21.00.20.90.20.30.70.30.60.30.20.3
Patch foraging water rate 12 sec0.40.93.6-0.5-0.8-1.6-0.8-1.9-0.20.3-1.2-0.1-1.80.8-1.8-0.50.3-0.0-0.5-0.0-0.5-0.2-0.4-0.8
Patch foraging water rate 18 sec1.52.36.50.40.2-1.10.1-1.00.9-0.9-0.2-1.6-2.4-0.4-2.5-1.9-1.1-1.5-2.0-1.5-1.8-1.5-2.0-2.4
Patch foraging water rate 24 sec0.70.94.2-0.7-0.4-1.2-0.3-1.20.1-0.2-0.5-0.6-2.00.0-1.9-0.8-0.5-0.6-0.8-0.7-1.0-0.6-1.2-1.5
Patch foraging water rate 6 sec1.72.56.02.42.32.12.01.62.2-2.01.6-1.51.1-0.50.9-0.9-1.6-1.7-0.6-1.4-1.4-1.5-1.2-0.4
Seeking ratio, delayed vs. immediate footshock1.51.84.4-1.7-1.7-1.5-1.7-2.1-1.11.2-1.81.5-0.81.5-0.61.31.41.30.81.40.41.50.80.8
Distance traveled before self-admin0.60.82.2-1.0-1.2-1.2-1.2-0.9-1.21.1-0.90.7-0.60.0-0.90.40.81.0-0.60.70.81.50.60.1
Distance traveled after self-admin0.50.61.6-0.5-1.0-1.3-0.9-0.9-1.21.3-0.90.4-0.60.5-0.70.21.00.6-0.10.70.7-0.10.80.0
Extensor digitorum longus weight0.31.24.7-0.7-0.50.3-0.30.5-1.00.9-0.31.01.20.61.51.30.81.01.61.01.32.21.31.2
Bone: elastic displacement0.40.52.1-0.9-0.6-1.0-0.4-1.0-0.40.1-0.8-0.0-1.30.8-1.00.1-0.0-0.20.2-0.3-0.3-1.4-0.5-0.8
Bone: elastic work1.11.43.5-1.7-1.5-1.3-1.2-1.4-1.41.1-1.71.2-0.71.9-0.31.31.00.91.60.80.8-0.30.60.4
Bone: endosteal estimation0.40.93.11.11.21.61.11.50.8-0.71.0-0.21.7-0.01.80.6-0.4-0.41.0-0.2-0.1-0.70.10.6
Bone: endosteal perimeter1.22.54.61.31.81.81.92.11.6-1.91.9-1.70.6-1.70.8-1.1-2.0-1.9-0.7-1.9-1.4-0.3-1.6-1.2
Epididymis fat weight0.10.31.00.10.40.31.00.70.2-0.40.5-0.6-0.1-0.70.2-0.4-0.7-0.7-0.1-0.8-0.40.0-0.5-0.6
Delta time in closed arm before/after self-admin0.50.52.8-1.1-0.9-0.9-0.8-1.0-0.50.4-0.70.2-0.9-0.4-0.8-0.30.40.3-0.50.3-0.11.70.0-0.3
Delta time in open arm before/after self-admin2.12.15.91.61.72.41.82.41.3-1.31.6-0.42.30.02.40.8-1.0-0.61.2-0.60.0-1.1-0.00.8
Diff in mean of infusions in LGA sessions0.20.30.80.60.60.80.70.70.6-0.60.6-0.20.9-0.50.8-0.2-0.3-0.2-0.0-0.2-0.10.40.00.3
Delay discount exponential model param0.30.41.10.40.30.60.30.7-0.20.20.10.31.00.81.01.00.00.21.00.30.7-0.30.40.7
Extinction: sum of active levers before priming1.82.05.7-2.1-1.8-2.1-2.0-2.4-1.11.1-2.01.0-1.81.8-1.60.41.00.80.80.80.1-0.4-0.1-0.2
Active lever presses in extinction session 61.11.14.2-0.4-0.5-1.4-0.4-1.0-0.10.0-0.5-0.8-2.0-0.3-2.0-0.7-0.2-0.7-1.2-0.8-0.9-1.7-0.8-1.7
Bone: final force0.20.31.50.30.40.80.60.90.1-0.10.20.11.10.21.20.6-0.1-0.00.80.10.40.40.20.6
Bone: final moment0.20.31.30.20.30.70.50.70.1-0.10.10.20.90.31.10.7-0.1-0.00.90.20.30.30.20.6
Food consumed during 24 hour testing period3.54.812.33.23.13.52.83.02.7-2.32.8-1.42.9-1.32.6-0.5-1.7-1.7-0.2-1.2-1.2-1.8-0.70.4
Glucose0.10.20.7-0.2-0.10.10.20.7-0.50.4-0.10.40.50.50.70.8-0.00.30.90.30.80.10.30.5
Heart weight0.71.14.1-1.3-1.3-1.5-0.9-2.0-0.60.8-1.10.7-1.00.4-1.10.21.20.8-0.40.9-0.11.90.40.0
Delay discount hyperbolic model param0.40.41.40.40.30.60.30.8-0.30.30.10.41.10.81.11.00.10.31.20.40.9-0.30.50.8
Intermittent access intake day 1-15 change1.63.35.02.22.21.72.11.82.0-2.02.2-2.20.2-2.00.1-2.0-1.8-2.0-1.6-2.0-1.7-1.3-1.6-1.4
Intermittent access intake escalation1.02.03.11.71.71.31.71.41.6-1.51.8-1.70.1-1.50.1-1.6-1.4-1.6-1.2-1.6-1.4-1.2-1.2-1.2
Intermittent access intake escalation 21.92.13.31.81.81.41.81.41.6-1.51.7-1.70.2-1.20.2-1.4-1.5-1.7-1.0-1.5-1.4-1.8-1.3-1.2
Intermitt. access day 1 inactive lever presses0.31.03.30.50.6-0.20.40.00.9-1.00.3-1.1-1.2-0.4-1.3-0.8-1.1-1.2-1.0-1.2-1.2-1.8-1.3-1.4
Intermitt. access day 15 inactive lever presses0.30.61.3-0.6-0.7-0.4-0.7-0.4-1.01.0-0.80.80.11.10.11.00.90.91.10.81.00.20.80.6
Intermitt. access escalation Index0.30.51.7-0.7-0.7-1.0-0.7-1.3-0.20.2-0.90.2-1.30.9-1.10.10.20.10.20.0-0.3-0.5-0.4-0.5
Intermittent access day 1 total infusions1.72.75.1-1.9-1.8-1.4-1.9-1.6-1.81.8-2.01.9-0.32.3-0.11.91.81.72.01.71.60.51.41.2
Intermittent access day 15 total infusions0.20.30.6-0.7-0.7-0.8-0.8-0.7-0.70.7-0.70.4-0.50.6-0.50.20.70.50.40.50.40.30.40.1
Intermittent access terminal intake (last 3 days)0.30.40.7-0.7-0.7-0.7-0.8-0.6-0.80.8-0.70.4-0.50.7-0.50.30.70.50.60.50.50.00.40.1
Intermittent access total infusions0.80.91.6-1.0-1.0-0.9-1.1-0.8-1.21.2-1.11.0-0.21.3-0.11.11.11.01.11.00.90.10.90.6
Intermittent access day 1 locomotion1.82.36.9-1.7-1.6-1.6-1.6-1.9-1.31.3-2.01.5-1.02.6-0.62.01.41.22.01.20.8-1.20.70.6
Intermittent access day 15 total locomotion0.81.53.4-1.1-1.1-0.7-1.1-0.8-1.41.4-1.21.40.21.80.41.61.41.31.81.31.3-0.11.31.2
Intermittent access total locomotion2.32.86.7-1.5-1.5-0.9-1.5-1.1-1.71.8-1.72.00.32.60.62.41.81.82.51.81.7-0.31.71.6
Intermittent access standard deviation0.71.42.51.31.20.71.30.91.1-1.11.3-1.6-0.3-1.4-0.4-1.6-1.2-1.3-1.4-1.4-1.2-1.0-1.2-1.3
Left kidney weight1.04.79.22.22.62.42.72.52.4-2.52.8-2.41.2-3.01.0-1.7-2.2-2.4-2.0-2.2-2.10.8-1.6-1.3
Right kidney weight0.83.57.01.72.42.62.52.61.9-2.22.5-1.71.7-2.31.8-0.9-1.9-1.9-0.8-1.8-1.50.4-1.2-0.6
Cocaine induced anxiety0.40.52.3-0.7-0.6-1.1-0.7-1.1-0.20.1-0.7-0.2-1.50.1-1.5-0.7-0.1-0.1-0.6-0.2-0.4-0.0-0.7-0.9
Post-drug Anxiety0.20.30.8-0.6-0.7-0.8-0.6-0.9-0.50.5-0.70.3-0.60.1-0.6-0.20.50.4-0.30.30.20.60.2-0.1
Baseline Anxiety0.40.52.00.20.10.70.20.6-0.10.20.40.51.4-0.51.40.30.50.50.20.50.71.11.01.1
Tail length2.811.116.14.03.93.13.83.53.7-3.63.9-4.00.6-3.60.2-3.9-3.7-3.7-3.0-3.7-3.0-1.9-2.9-2.5
Length with tail1.25.311.22.42.72.53.03.32.1-2.23.1-2.50.8-3.10.9-2.1-2.6-2.4-1.9-2.5-1.5-0.9-1.7-1.4
Length without tail0.10.41.7-0.30.00.50.41.1-0.60.50.30.50.90.01.31.20.20.30.90.30.9-0.10.70.7
Times rat made contact with spout0.00.00.50.20.1-0.00.1-0.30.2-0.1-0.00.10.10.2-0.0-0.10.20.00.10.2-0.2-0.70.10.1
Lifetime Intake0.40.50.9-0.8-0.8-0.7-0.9-0.6-1.00.9-0.90.7-0.31.0-0.20.70.80.70.80.70.7-0.00.70.4
Liver weight, left0.50.81.70.80.90.71.21.30.8-1.01.0-1.0-0.1-0.70.1-0.5-1.3-1.1-0.4-1.2-0.7-1.3-1.0-0.8
Liver weight, right0.91.63.50.91.30.91.61.41.2-1.41.1-1.3-0.2-0.80.0-0.5-1.9-1.7-0.5-1.6-1.3-1.8-1.6-1.2
Locomotor activity1.21.95.50.0-0.30.5-0.4-0.2-0.60.7-0.91.61.92.01.92.31.21.22.11.51.40.31.62.1
Locomotor testing distance1.12.04.50.1-0.30.5-0.6-0.2-0.70.9-1.01.61.92.01.82.11.31.42.01.61.50.91.72.1
Locomotor testing rearing0.61.24.91.51.42.01.31.11.2-0.90.9-0.22.2-0.02.10.5-0.1-0.40.50.0-0.3-0.00.41.0
Locomotion in novel chamber1.21.54.3-0.6-0.50.4-0.5-0.3-0.60.7-0.61.61.61.41.72.11.11.11.81.31.11.11.41.9
Locomotion in novel chamber post-restriction0.50.88.51.00.80.40.70.10.7-0.6-0.1-0.4-0.11.4-0.10.2-0.7-0.80.7-0.6-0.6-2.9-0.7-0.3
Fecal boli incidents, locomotor time 11.72.55.81.71.81.61.82.01.4-1.61.9-1.60.3-2.40.2-1.2-1.9-1.6-2.2-1.6-1.10.3-1.3-1.1
Change in fecal boli incidents, locomotor task0.80.82.00.40.4-0.30.2-0.81.0-0.80.0-0.9-1.0-0.0-1.2-1.3-0.6-0.9-0.8-0.8-1.4-1.3-1.2-1.1
Time >=10cm from walls, locomotor time 10.30.33.30.70.40.30.10.00.2-0.00.4-0.10.5-0.60.1-0.90.30.1-0.90.20.01.80.30.3
Bouts of movement, locomotor time 10.30.41.6-0.2-0.2-0.6-0.2-0.4-0.20.1-0.1-0.5-1.0-0.6-1.1-1.3-0.1-0.3-1.1-0.3-0.2-0.2-0.3-0.9
Total resting periods, locomotor time 10.50.62.3-0.5-0.4-1.0-0.4-0.7-0.30.3-0.3-0.5-1.4-0.5-1.5-1.30.0-0.3-1.2-0.4-0.4-0.2-0.5-1.1
Rest time, locomotor task time 10.30.31.2-0.7-0.6-1.0-0.5-0.6-0.50.3-0.4-0.3-1.1-0.4-1.1-0.40.1-0.1-0.5-0.2-0.10.2-0.3-0.9
Distance moved, locomotor task time 10.71.03.7-0.1-0.20.4-0.20.0-0.50.7-0.41.11.11.51.31.40.91.01.91.11.00.11.21.4
Vertical activity count, locomotor time 10.81.96.01.81.72.31.72.11.1-0.81.7-0.32.5-1.42.4-0.0-0.6-0.30.00.00.21.20.61.2
Time >=10cm from walls, locomotor time 20.60.92.4-0.8-1.1-0.8-1.1-0.3-1.31.3-0.81.0-0.00.70.00.51.11.30.51.01.50.91.10.9
Bouts of movement, locomotor time 20.20.41.6-0.7-0.8-1.0-0.8-1.3-0.50.6-0.80.3-0.70.3-0.9-0.20.70.4-0.20.40.1-0.20.2-0.2
Total resting periods, locomotor time 20.10.10.6-0.3-0.4-0.6-0.5-0.8-0.30.4-0.40.1-0.3-0.1-0.5-0.30.50.3-0.30.30.10.00.2-0.1
Rest time, locomotor task time 20.30.31.10.80.70.70.60.60.6-0.50.7-0.50.4-1.10.2-0.7-0.4-0.3-0.7-0.3-0.30.3-0.3-0.1
Distance moved, locomotor task time 22.12.54.1-1.8-1.7-1.3-1.5-1.1-2.01.9-1.71.8-0.12.00.31.51.81.72.01.61.90.31.81.2
Vertical activity count, locomotor time 20.60.94.00.60.81.41.11.40.3-0.20.90.21.6-0.42.00.90.1-0.20.80.20.50.70.91.0
Light reinforcement 15.413.227.34.85.05.24.85.04.4-4.24.6-3.13.5-3.23.3-1.4-3.9-3.5-1.5-2.9-2.6-1.3-2.2-0.5
Light reinforcement 25.78.820.74.24.14.34.04.63.2-3.03.9-2.53.1-2.72.8-1.4-3.0-2.6-1.2-2.3-1.5-1.6-1.4-0.2
Bone: marrow area0.40.93.31.11.21.61.11.50.8-0.70.9-0.21.7-0.01.80.6-0.4-0.41.0-0.2-0.0-0.50.20.7
Bone: maximum diameter0.40.71.7-0.10.50.40.70.80.5-0.90.9-1.1-0.5-1.1-0.2-0.9-1.2-1.1-0.4-1.3-1.00.1-1.3-1.3
Bone: maximum force0.10.21.00.00.10.50.30.8-0.10.10.00.20.70.41.00.6-0.10.11.00.10.5-0.10.20.5
Bone: maximum moment0.10.21.2-0.10.10.40.30.6-0.10.0-0.00.20.60.50.90.7-0.10.01.10.10.3-0.20.10.4
Mean time between licks in bursts0.10.41.5-0.00.40.20.6-0.20.7-0.80.4-0.5-0.4-0.3-0.30.1-0.4-0.7-0.1-0.7-1.2-1.2-0.8-0.7
Mean num. licks in bursts0.20.41.3-0.4-0.7-1.0-0.8-0.8-0.40.5-0.70.2-1.00.3-1.2-0.50.20.3-0.60.20.3-0.7-0.1-0.2
Cd content in liver1.61.75.4-2.3-1.6-1.1-1.3-1.7-1.51.2-1.21.5-0.40.7-0.22.01.41.21.11.20.51.60.90.6
Co content in liver2.02.36.5-2.4-2.1-2.6-2.0-2.5-1.51.2-1.90.7-2.51.0-2.20.50.80.70.30.40.10.6-0.2-0.8
Cu content in liver0.30.42.4-0.8-0.6-0.5-0.4-0.5-0.60.4-0.60.50.00.50.20.90.40.40.80.40.31.60.30.2
Fe content in liver1.31.64.30.70.4-0.80.30.30.5-0.70.4-1.5-1.9-1.0-1.9-2.1-1.4-1.1-1.9-1.4-0.8-1.3-1.5-1.9
K content in liver1.21.14.3-0.9-1.0-1.3-1.2-1.1-1.00.9-1.60.8-0.72.1-0.40.90.60.61.70.60.7-1.30.30.2
Mg content in liver0.70.72.8-0.7-0.8-1.2-1.1-1.1-0.50.3-1.50.2-1.11.7-0.80.6-0.1-0.01.1-0.00.1-1.3-0.4-0.4
Mn content in liver0.40.40.90.50.80.80.90.60.7-0.90.5-0.60.4-0.30.60.4-0.7-0.90.3-0.7-0.80.3-0.6-0.4
Na content in liver0.10.10.90.60.30.1-0.00.40.1-0.00.0-0.20.10.20.0-0.3-0.2-0.10.1-0.10.2-0.90.0-0.0
Rb content in liver0.20.20.50.50.50.30.30.20.6-0.60.3-0.50.1-0.10.1-0.2-0.7-0.60.0-0.5-0.6-0.4-0.5-0.4
Se content in liver1.61.94.20.80.8-0.11.01.10.8-1.10.7-1.8-1.4-1.2-1.2-2.0-2.0-1.7-1.6-1.9-1.0-0.8-1.9-2.1
Sr content in liver0.70.61.6-1.1-0.9-0.5-0.9-0.9-0.80.7-1.10.9-0.31.2-0.01.20.70.61.20.60.50.10.50.4
Zn content in liver1.01.12.2-1.5-1.4-1.2-1.5-1.3-1.21.1-1.41.0-0.51.1-0.30.81.01.00.80.90.81.50.70.4
Bone: minimum diameter1.12.14.71.71.92.12.02.21.6-1.61.8-1.21.3-1.11.3-0.7-1.4-1.4-0.2-1.3-1.0-1.1-0.9-0.3
Time in familiar zone, hab. session 10.80.72.00.50.70.50.70.31.0-1.01.0-1.0-0.2-1.4-0.4-1.2-0.7-0.8-1.2-0.9-1.2-0.2-0.9-0.8
Time in novel zone, hab. session 11.61.63.9-0.8-1.3-1.2-1.3-1.3-1.31.5-1.71.4-0.22.0-0.21.01.41.51.11.51.5-0.01.41.1
Total zone transitions, hab. session 10.30.41.70.90.71.00.70.70.4-0.20.30.11.30.21.20.30.00.00.50.20.20.30.50.7
Total locomotion distance, hab. session 10.30.41.00.60.30.60.30.20.20.0-0.10.41.01.01.01.00.30.21.00.40.4-0.40.50.8
Locomotion velocity, hab. session 10.30.51.60.80.61.00.60.60.4-0.20.10.21.20.81.31.1-0.0-0.11.10.20.2-0.30.30.8
Time in familiar zone, hab. session 21.21.32.11.21.41.21.41.11.4-1.41.3-1.10.4-1.20.4-0.6-1.2-1.3-0.7-1.1-1.3-1.2-1.0-0.6
Time in novel zone, hab. session 23.23.24.9-1.9-2.0-1.4-1.9-1.5-2.12.1-1.72.10.11.90.21.52.22.21.82.12.01.72.01.6
Total zone transitions, hab. session 20.50.71.71.21.11.11.10.31.3-1.10.5-0.70.90.20.80.0-0.7-0.90.3-0.6-1.0-0.7-0.7-0.2
Total locomotion distance, hab. session 20.40.51.70.80.81.10.80.60.6-0.60.2-0.11.20.61.31.0-0.3-0.41.0-0.1-0.20.0-0.00.4
Locomotion velocity, hab. session 20.40.51.80.90.91.10.80.80.7-0.60.3-0.11.30.51.40.9-0.4-0.40.8-0.1-0.10.1-0.00.4
Novel to familiar place preference ratio1.11.22.1-0.7-0.9-0.5-1.0-0.9-0.91.1-1.01.40.41.40.51.21.41.31.31.41.00.11.31.4
Novelty place preference1.31.42.9-0.6-0.8-0.3-1.0-0.8-1.01.2-0.91.60.71.50.81.41.51.51.51.61.20.21.61.7
Time in novel zone, NPP test1.71.83.3-0.8-1.2-0.8-1.3-1.2-1.21.5-1.31.70.41.80.31.31.71.61.41.81.40.01.61.6
Total zone transitions, NPP test0.81.12.61.11.41.51.61.31.3-1.41.1-1.01.0-0.61.1-0.0-1.2-1.20.1-1.1-1.0-0.0-0.9-0.4
Total locomotion distance, NPP test0.10.20.40.40.50.60.70.30.5-0.50.2-0.30.60.40.70.4-0.3-0.40.6-0.3-0.40.0-0.2-0.0
Locomotion velocity, NPP test0.30.51.20.50.81.01.10.90.6-0.80.6-0.50.8-0.11.00.5-0.6-0.70.6-0.6-0.50.4-0.4-0.2
Intraocular pressure1.62.25.1-2.3-2.1-2.0-1.9-2.2-1.71.5-1.81.2-1.51.0-1.30.91.51.30.41.10.81.60.90.2
Delta distance traveled before/after self-admin0.20.21.90.40.30.10.4-0.10.3-0.2-0.1-0.10.10.70.30.2-0.1-0.40.6-0.0-0.3-1.4-0.00.1
Delta ambulatory time before/after self-admin0.70.95.71.21.10.61.20.41.1-0.90.6-0.90.00.20.2-0.3-0.7-1.30.1-0.8-1.1-2.4-0.7-0.6
Parametrial fat weight0.30.82.60.71.11.41.61.60.5-0.71.2-0.61.0-1.01.2-0.1-0.7-0.70.0-0.7-0.20.6-0.1-0.0
Pavlov. Cond. lever latency0.40.41.40.10.00.5-0.1-0.1-0.10.3-0.00.71.20.51.11.00.80.60.80.80.40.60.91.1
Pavlov. Cond. magazine entry latency0.40.51.9-0.6-0.8-1.2-0.7-1.0-0.60.5-0.80.2-1.40.5-1.4-0.30.20.2-0.20.10.1-0.3-0.3-0.5
Pavlov. Cond. change in total contacts1.11.12.40.40.5-0.00.60.30.7-0.90.5-1.2-1.3-0.7-1.2-1.3-1.4-1.3-1.1-1.4-1.1-1.3-1.6-1.6
Pavlov. Cond. index score0.40.52.7-0.6-0.6-1.1-0.4-0.7-0.40.2-0.6-0.2-1.70.2-1.5-0.6-0.3-0.2-0.3-0.4-0.2-0.8-0.7-1.0
Pavlov. Cond. latency score0.30.31.6-0.4-0.3-0.7-0.1-0.3-0.2-0.0-0.3-0.4-1.3-0.1-1.2-0.6-0.5-0.4-0.4-0.6-0.3-0.6-0.8-1.0
Pavlov. Cond. lever contacts0.40.42.1-0.4-0.5-0.9-0.4-0.5-0.30.1-0.5-0.4-1.40.0-1.4-0.9-0.4-0.2-0.5-0.5-0.1-0.4-0.7-1.0
Pavlov. Cond. magazine entry number0.91.13.61.21.31.81.31.41.1-1.01.4-0.41.9-0.81.80.1-0.4-0.50.1-0.3-0.40.20.20.6
Pavlov. Cond. intertrial magazine entries0.91.12.9-0.30.3-0.20.40.40.6-1.00.6-1.3-1.2-1.4-0.9-1.2-1.4-1.3-1.2-1.5-1.20.3-1.6-1.7
Pavlov. Cond. lever-magazine prob. diff.0.50.73.0-0.9-0.9-1.4-0.7-0.9-0.80.5-0.90.1-1.70.5-1.6-0.3-0.10.1-0.1-0.20.1-0.8-0.5-0.9
Pavlov. Cond. response bias0.81.04.3-0.7-1.0-1.6-1.0-1.3-0.60.5-1.1-0.1-2.10.5-2.1-0.7-0.10.0-0.6-0.2-0.1-0.5-0.6-1.1
Pavlov. Cond. lever latency0.10.21.0-0.7-0.4-0.1-0.30.2-0.60.50.00.40.0-0.30.20.20.20.50.20.30.61.00.40.3
Pavlov. Cond. magazine entry latency0.10.10.40.10.30.20.10.30.3-0.40.5-0.30.1-0.6-0.0-0.6-0.2-0.3-0.4-0.4-0.4-0.4-0.3-0.3
Pavlov. Cond. change in total contacts0.20.31.00.30.0-0.5-0.0-0.70.4-0.4-0.3-0.6-0.80.1-1.0-0.7-0.3-0.5-0.8-0.5-0.7-0.5-0.6-0.8
Pavlov. Cond. index score0.20.20.90.40.3-0.20.1-0.20.5-0.5-0.0-0.5-0.3-0.0-0.5-0.7-0.3-0.5-0.6-0.5-0.6-0.9-0.5-0.5
Pavlov. Cond. latency score0.20.31.40.50.4-0.10.2-0.10.6-0.60.1-0.6-0.3-0.1-0.5-0.8-0.4-0.6-0.6-0.6-0.7-1.2-0.6-0.6
Pavlov. Cond. lever contacts0.10.10.50.70.50.20.3-0.10.6-0.50.1-0.40.20.10.0-0.2-0.2-0.4-0.2-0.2-0.5-0.7-0.2-0.1
Pavlov. Cond. magazine entry number0.10.10.5-0.2-0.20.10.0-0.1-0.30.4-0.20.50.20.40.30.70.40.40.50.50.30.10.40.5
Pavlov. Cond. intertrial magazine entries1.21.84.21.71.81.82.11.51.7-1.61.5-1.30.9-1.10.8-0.5-1.5-1.5-0.9-1.3-1.3-0.4-1.1-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.30.1-0.3-0.0-0.30.4-0.4-0.1-0.4-0.40.0-0.6-0.6-0.2-0.4-0.5-0.4-0.5-1.0-0.4-0.5
Pavlov. Cond. response bias0.00.00.10.30.2-0.10.1-0.20.3-0.2-0.2-0.20.10.2-0.1-0.2-0.0-0.2-0.1-0.1-0.2-0.3-0.1-0.1
Time in closed arm before self-admin1.11.46.51.41.20.30.90.21.2-1.10.7-1.2-0.6-0.2-0.9-0.7-1.2-1.4-1.1-1.2-1.3-2.6-1.5-1.2
Time in closed arm after self-admin0.80.83.70.10.3-0.20.1-0.20.7-0.70.4-0.7-0.9-1.5-1.1-1.4-0.8-0.7-1.9-0.7-0.90.9-1.1-1.0
Time in open arm before self-admin0.70.84.2-1.2-1.1-1.1-1.0-0.9-0.90.9-0.70.4-0.7-0.5-0.6-0.31.00.6-0.40.70.32.00.70.0
Time in open arm after self-admin0.50.52.3-0.4-0.50.1-0.30.2-0.60.6-0.30.70.61.10.81.00.70.71.50.60.80.11.00.9
Bone: periosteal estimation0.51.23.41.11.41.81.41.71.1-1.11.3-0.61.6-0.41.70.1-0.8-0.90.7-0.7-0.5-0.3-0.40.2
Bone: periosteal perimeter1.01.62.80.61.41.41.51.51.3-1.71.6-1.40.3-1.40.6-0.8-1.6-1.7-0.4-1.7-1.50.1-1.5-1.1
Bone: post-yield work0.30.41.60.90.71.00.51.10.4-0.20.70.01.3-0.21.10.1-0.10.10.00.20.3-0.10.40.8
Progressive ratio test 1 active lever presses1.11.32.4-1.2-1.3-0.9-1.2-0.9-1.41.3-1.31.3-0.01.50.11.31.21.21.51.31.20.41.11.0
Progressive ratio test 1 breakpoint1.21.42.3-1.3-1.3-1.0-1.3-0.9-1.41.4-1.31.3-0.01.50.11.31.31.31.41.31.30.51.21.0
Progressive ratio test 1 inactive lever presses0.20.30.6-0.6-0.6-0.7-0.7-0.4-0.80.7-0.70.4-0.50.7-0.50.40.40.40.40.40.6-0.40.40.1
Progressive ratio test 2 active lever presses0.91.01.7-1.1-1.2-0.8-1.1-0.6-1.31.3-0.91.10.10.70.10.91.21.20.71.21.11.31.20.8
Progressive ratio test 2 breakpoint1.01.11.9-1.1-1.2-0.8-1.2-0.7-1.41.4-0.91.10.10.70.10.91.31.20.71.21.21.41.30.9
Progressive ratio test 2 inactive lever presses1.01.72.9-1.5-1.5-1.3-1.5-1.2-1.71.7-1.41.3-0.31.1-0.31.11.61.41.01.41.31.31.40.8
Incentive Sensitization - Responses0.20.33.9-0.3-0.3-0.1-0.30.1-0.50.50.10.20.3-0.60.2-0.30.50.5-0.20.40.42.00.60.3
Incentive Sensitization - Breakpoint0.20.33.2-0.2-0.20.0-0.20.1-0.40.40.20.10.3-0.60.2-0.30.40.4-0.30.30.41.80.60.2
Sum of active levers in priming session hrs 5-60.40.41.5-0.2-0.10.3-0.1-0.1-0.10.2-0.30.70.80.91.01.10.40.51.20.60.5-0.70.60.9
Progressive ratio0.50.83.00.80.91.30.81.20.7-0.61.2-0.31.7-1.01.4-0.5-0.4-0.1-0.2-0.20.01.30.10.5
Food seeking constrained by brief footshock2.02.44.21.82.01.62.01.71.7-1.91.9-1.80.6-1.50.3-1.2-1.8-1.8-1.1-1.8-1.3-0.9-1.5-1.1
Seeking ratio, punishment vs. effort0.50.83.30.80.80.41.00.60.6-0.80.6-1.0-0.7-0.3-0.5-0.4-1.0-1.2-0.5-1.1-0.8-1.8-1.0-1.0
Retroperitoneal fat weight0.20.93.80.30.91.41.91.60.4-0.61.0-0.41.3-0.61.80.5-0.8-0.70.8-0.7-0.10.4-0.20.1
Reaction time number correct0.40.82.8-1.3-1.0-1.5-1.3-1.4-0.70.5-0.90.0-1.70.3-1.7-0.60.30.2-0.20.0-0.10.3-0.4-0.8
Reaction time mean minus median0.20.51.7-1.2-0.9-0.9-0.8-0.2-1.31.2-0.40.6-0.7-0.0-0.5-0.40.90.70.10.50.90.40.70.1
Reaction time mean minus median AUC0.41.03.1-1.7-1.3-1.3-1.1-0.6-1.81.6-0.81.0-0.80.5-0.60.31.11.00.60.81.20.20.80.2
Reaction time num false alarms0.91.34.2-2.0-1.5-1.0-1.4-1.2-1.31.0-1.01.2-0.30.40.01.21.21.10.81.00.62.10.80.5
Reaction time num false alarms AUC0.71.13.4-1.8-1.5-1.3-1.4-1.5-1.10.8-1.10.9-0.70.4-0.60.81.00.90.40.80.31.60.40.1
Reaction time trials correct on left0.40.82.8-1.3-1.0-1.5-1.3-1.4-0.70.5-0.90.0-1.70.3-1.7-0.60.30.2-0.20.0-0.10.3-0.4-0.8
Reaction time trials on left0.40.82.6-1.4-1.1-1.5-1.4-1.4-0.80.6-1.00.2-1.60.4-1.6-0.50.40.3-0.10.1-0.00.4-0.3-0.7
Reaction time mean2.13.47.4-2.7-2.4-2.1-2.0-1.5-2.62.5-1.72.1-0.91.2-0.51.32.22.11.21.81.90.51.91.1
Reaction time mean AUC2.03.26.9-2.6-2.4-2.0-1.9-1.5-2.62.4-1.72.1-0.91.3-0.51.32.12.01.31.71.90.41.81.0
Median of all reaction times2.63.67.7-2.8-2.5-2.2-2.1-1.8-2.62.4-1.92.2-1.01.4-0.61.62.22.11.31.81.90.41.81.1
Reaction time omissions1.21.83.7-1.8-1.5-0.8-1.2-0.3-1.91.8-0.51.60.5-0.40.60.21.61.70.61.41.71.71.81.3
Reaction time false alarm rate0.20.30.8-0.9-0.8-0.4-0.6-0.6-0.50.4-0.50.6-0.00.20.10.80.60.50.40.50.20.90.40.3
Reaction time premature initiation rate4.66.410.12.93.22.63.12.63.2-3.12.9-2.90.7-2.20.6-1.9-2.8-3.0-1.6-2.8-2.6-2.0-2.2-1.8
Reaction time premature initiations2.24.06.32.02.31.72.11.72.5-2.52.2-2.4-0.0-1.7-0.1-1.9-2.2-2.5-1.5-2.4-2.3-1.6-2.1-1.8
Std. dev. reaction times0.50.92.7-1.5-1.2-1.0-0.9-0.3-1.61.6-0.51.0-0.5-0.0-0.3-0.11.31.10.30.81.20.31.20.5
Reaction time trials completed0.40.82.6-1.4-1.1-1.5-1.4-1.4-0.80.6-1.00.2-1.60.4-1.6-0.50.40.3-0.10.1-0.00.4-0.3-0.7
Reaction time trials AUC0.50.92.3-1.4-1.2-1.5-1.5-1.5-0.90.7-1.10.3-1.50.5-1.5-0.30.60.50.00.30.10.6-0.1-0.5
Run reversals in cocaine runway, females2.22.24.9-1.0-1.00.0-0.80.4-1.51.4-0.81.71.61.01.91.71.31.72.11.62.21.41.92.0
Run reversals in cocaine runway, males0.50.51.5-0.3-0.7-0.6-0.7-0.8-1.01.0-0.60.50.1-0.2-0.3-0.41.10.9-0.40.90.71.20.80.4
Latency to leave start box in cocaine runway1.31.53.3-0.6-0.50.3-0.30.4-1.21.3-0.31.31.40.61.61.51.21.31.21.41.71.81.71.7
Latency to leave start box in cocaine runway, F1.51.73.5-0.9-1.1-0.4-1.0-0.4-1.51.5-1.21.70.71.60.91.41.31.61.51.71.90.91.51.6
Latency to leave start box in cocaine runway, M0.70.72.20.50.81.21.11.40.3-0.21.1-0.21.2-0.91.50.5-0.1-0.30.1-0.10.11.20.50.4
Std. dev. time between licks in bursts0.81.12.11.11.31.31.41.01.4-1.41.5-1.10.6-1.10.5-0.5-1.0-1.2-0.5-1.1-1.3-0.3-0.9-0.6
Total sessions with >9 infusions1.51.84.2-1.6-1.6-2.1-1.7-1.9-1.21.1-1.90.8-1.91.9-1.80.70.80.70.90.60.4-1.20.0-0.4
Short access day 1 total inactive lever presses0.20.30.9-0.1-0.10.1-0.20.6-0.70.6-0.20.40.40.60.40.70.30.40.90.30.9-0.60.60.5
Short access day 10 total inactive lever presses0.92.19.21.41.40.81.40.71.7-1.70.9-1.5-0.6-0.3-0.6-0.9-1.7-1.8-0.7-1.7-1.7-3.0-1.8-1.4
Short access day 1 total infusions1.52.05.7-1.9-1.9-2.4-1.9-1.8-1.51.3-1.90.7-2.31.2-2.3-0.20.80.80.20.60.6-0.10.0-0.6
Short access day 10 total infusions0.70.83.5-0.8-0.8-0.8-0.8-0.9-0.80.8-1.20.7-0.61.9-0.41.00.70.61.40.60.5-1.40.40.3
Short access total infusions0.70.91.7-1.1-1.1-1.3-1.2-1.1-1.21.1-1.30.7-1.01.3-0.90.50.90.70.80.60.7-0.50.50.1
Short access day 1 locomotion2.12.65.4-2.2-2.2-2.3-2.2-2.0-1.91.7-2.21.4-1.71.9-1.60.91.31.41.01.21.1-0.00.70.2
Short access day 10 total locomotion1.11.96.3-1.3-1.4-1.6-1.3-2.1-0.91.0-1.91.1-1.32.5-0.91.61.10.81.60.80.2-2.40.40.1
Short access total locomotion2.53.07.7-2.0-2.0-2.2-2.0-2.4-1.61.5-2.41.5-1.82.8-1.41.81.41.21.71.20.7-1.70.50.2
One hour access (0.3 mA shock)0.60.71.2-0.9-0.8-0.6-0.9-0.6-1.01.1-0.70.9-0.00.90.10.61.10.90.90.90.80.70.90.7
Compulsive drug intake1.01.23.50.10.2-0.70.2-0.80.7-0.8-0.1-1.1-1.9-0.3-1.8-1.3-0.7-1.1-1.1-1.2-1.4-1.6-1.5-1.7
One hour access (shock baseline)0.91.42.6-0.9-0.9-0.2-0.9-0.2-1.31.3-0.51.41.00.71.11.31.41.51.31.51.51.41.61.5
Social response proportion0.81.04.7-0.9-0.70.0-0.7-0.1-0.80.8-0.31.20.90.21.01.10.81.11.01.01.12.21.11.2
Social responses0.30.41.4-0.2-0.00.4-0.0-0.40.1-0.1-0.10.61.00.41.01.20.50.40.90.50.01.10.40.7
Social time0.60.91.80.80.70.20.5-0.11.0-0.80.5-1.1-0.7-0.7-0.9-1.1-0.7-1.1-1.3-1.0-1.4-1.2-1.1-1.2
Soleus weight0.10.31.2-0.3-0.30.1-0.3-0.3-0.30.4-0.20.50.70.30.70.40.70.60.60.60.41.10.70.7
Bone: stiffness0.50.93.50.40.31.10.51.5-0.30.30.40.51.70.11.90.80.10.51.00.61.21.00.91.3
Tibialis anterior weight0.10.20.9-0.9-0.5-0.6-0.2-0.5-0.40.1-0.2-0.2-0.8-0.4-0.6-0.60.1-0.0-0.1-0.3-0.20.9-0.2-0.7
Time to tail flick, vehicle, before self-admin0.30.31.00.70.50.70.40.60.4-0.30.7-0.30.6-1.00.3-0.6-0.40.1-0.9-0.20.00.3-0.20.1
Time to tail flick, vehicle, after self-admin0.70.94.40.50.71.30.61.10.6-0.61.30.11.5-1.51.4-0.0-0.10.1-0.60.20.22.10.50.8
Time to tail flick, test, before self-admin2.02.04.4-1.7-1.7-1.2-1.5-0.7-2.12.0-1.21.50.10.90.11.01.71.81.21.52.01.01.71.1
Time to tail flick, test, after self-admin0.10.10.40.30.30.40.40.50.1-0.10.5-0.30.4-0.70.3-0.20.00.0-0.3-0.20.20.10.1-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.90.10.40.50.30.70.2-0.30.7-0.10.4-0.90.4-0.0-0.1-0.3-0.3-0.2-0.10.90.20.0
Delta time to tail flick, test, before/after SA0.30.40.90.50.50.10.6-0.10.7-0.60.4-0.8-0.5-0.5-0.5-0.7-0.4-0.7-0.7-0.7-0.9-0.3-0.7-0.9
Tibia length0.10.30.80.40.4-0.1-0.00.70.1-0.20.2-0.7-0.6-0.4-0.5-0.9-0.9-0.5-0.7-0.70.0-0.4-0.6-0.8
Ambulatory time before self-admin0.81.32.4-1.2-1.5-1.4-1.4-1.1-1.51.5-1.41.1-0.50.8-0.71.11.21.30.21.01.21.10.90.5
Ambulatory time after self-admin0.10.10.50.1-0.3-0.5-0.2-0.3-0.50.7-0.40.1-0.20.5-0.30.20.60.1-0.00.30.3-0.70.50.0
Bone: tissue strength0.40.41.5-1.2-0.8-1.0-0.7-0.5-0.90.5-0.50.2-1.20.0-0.80.40.10.20.2-0.00.2-0.0-0.2-0.5
Total heroin consumption0.30.31.6-0.3-0.20.1-0.1-0.3-0.20.2-0.50.50.61.00.70.60.60.41.30.40.3-0.60.60.6
Bone: trabecular number3.35.512.23.32.51.31.91.23.0-2.61.9-2.8-0.4-1.9-1.1-3.5-2.4-2.5-3.1-2.3-2.5-2.0-2.3-2.0
Bone: trabecular spacing2.43.36.3-2.5-2.0-1.3-1.5-1.1-2.42.1-1.52.20.11.50.62.52.02.02.41.92.00.61.81.5
Bone: trabecular thickness0.40.41.91.40.90.80.70.71.0-0.70.4-0.60.60.10.4-1.1-0.6-0.5-0.3-0.4-0.3-0.5-0.3-0.0
Bone: trabecular tissue density2.94.27.2-1.8-1.9-1.1-1.7-0.8-2.42.5-1.72.50.91.61.12.52.32.52.02.52.72.22.52.3
Water consumed over 24 hours0.30.41.41.20.80.90.70.40.9-0.60.4-0.21.00.40.8-0.1-0.2-0.30.4-0.0-0.3-0.80.00.4
Number of responses in last shaping day1.11.25.6-0.9-0.8-1.6-0.9-1.3-0.30.1-0.7-0.5-2.3-0.5-2.4-1.1-0.2-0.2-1.3-0.5-0.60.1-0.8-1.4