Mri1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Mri1 0.11 0.05 7.6e-10 0.09 0.08 0.09 0.09 2.4e-10 2.3e-09 3.6e-10 8.1e-10
2 BLA gene expression Mri1 0.27 0.1 2.0e-09 0.15 0.15 0.13 0.16 3.4e-08 3.2e-08 2.8e-07 1.3e-08
3 NAcc gene expression Mri1 0.19 0.07 0.0e+00 0.14 0.17 0.17 0.18 8.1e-21 3.6e-25 3.8e-25 4.3e-27
4 IL gene expression Mri1 0.2 0.1 1.5e-03 0.12 0.09 0.08 0.09 8.7e-04 3.3e-03 7.1e-03 3.1e-03
5 IC gene expression Mri1 0.19 0.1 8.6e-05 0.09 0.09 0.11 0.09 1.0e-04 1.2e-04 3.3e-05 1.5e-04
6 Brain gene expression Mri1 0.53 0.12 0.0e+00 0.45 0.47 0.49 0.47 7.6e-46 4.6e-49 2.9e-51 2.2e-49
7 IC mRNA stability Mri1 0.15 0.08 3.5e-06 0.11 0.14 0.14 0.13 2.6e-05 2.8e-06 1.7e-06 3.1e-06
8 OFC gene expression Mri1 0.3 0.13 2.3e-04 0.1 0.04 0.03 0.04 2.1e-03 4.9e-02 6.0e-02 3.3e-02
9 pVTA mRNA stability Mri1 0.07 0.04 6.9e-06 0.04 0.05 0.06 0.05 7.7e-04 5.3e-05 2.2e-05 1.3e-04
10 pVTA gene expression Mri1 0.15 0.07 5.9e-09 0.12 0.11 0.11 0.11 4.9e-10 2.8e-09 7.4e-09 2.1e-09
11 OFC mRNA stability Mri1 0.51 0.23 4.1e-05 0.16 0.11 0.14 0.17 1.2e-04 1.4e-03 3.3e-04 8.4e-05
12 Liver gene expression Mri1 0.1 0.05 3.5e-08 0.05 0.06 0.06 0.05 4.9e-06 6.6e-07 1.0e-06 1.8e-06
13 Eye mRNA stability Mri1 0.49 0.18 1.6e-05 0.32 0.13 0.22 0.24 8.5e-06 4.4e-03 2.5e-04 1.1e-04
14 Brain mRNA stability Mri1 0.4 0.11 0.0e+00 0.4 0.47 0.47 0.47 3.3e-39 2.2e-48 1.4e-48 3.6e-49
15 PL mRNA stability Mri1 0.26 0.09 0.0e+00 0.24 0.25 0.24 0.26 3.0e-26 1.3e-27 1.9e-26 1.3e-28
16 Adipose mRNA stability Mri1 0.06 0.03 2.5e-07 0.05 0.05 0.05 0.06 7.0e-06 2.5e-06 3.0e-06 9.5e-07
17 NAcc mRNA stability Mri1 0.14 0.06 0.0e+00 0.15 0.16 0.16 0.16 3.1e-22 9.2e-23 1.6e-23 4.0e-24
18 BLA mRNA stability Mri1 0.25 0.09 2.9e-13 0.24 0.25 0.25 0.26 4.2e-13 1.4e-13 2.6e-13 8.9e-14
19 Liver mRNA stability Mri1 0.23 0.09 0.0e+00 0.23 0.22 0.23 0.23 1.0e-25 4.8e-24 5.3e-25 3.7e-25
20 LHb mRNA stability Mri1 0.22 0.12 2.0e-03 0.01 0.01 0.03 0.02 1.8e-01 1.5e-01 6.9e-02 1.3e-01
21 Adipose gene expression Mri1 0.33 0.1 0.0e+00 0.29 0.31 0.31 0.31 3.3e-32 5.0e-35 9.3e-35 4.2e-35

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density2.03.79.5-3.12.52.0-2.0-1.6-2.72.3-1.92.1-0.9-1.40.32.3-1.8-2.0-1.8-1.7-1.91.51.7-0.9
Area under the delay curve0.20.20.70.5-0.4-0.60.40.6-0.10.10.20.20.9-0.6-0.90.80.0-0.1-0.8-0.2-0.60.3-0.1-0.6
BMI with tail2.27.620.73.1-2.9-2.32.73.32.5-2.43.5-3.20.54.50.1-3.62.72.64.02.71.9-1.9-0.02.0
BMI without tail0.10.52.80.5-0.4-0.50.51.3-0.10.10.9-0.20.61.7-0.4-0.20.30.01.20.1-0.50.20.8-0.1
Body weight0.10.42.70.6-0.10.3-0.5-0.20.20.00.1-0.4-0.30.90.9-1.2-0.00.01.60.00.1-0.10.90.4
Weight adjusted by age0.10.41.60.9-0.9-0.60.90.40.8-0.70.3-0.60.4-0.6-0.50.70.40.7-0.60.60.5-0.4-1.30.2
Bone surface2.65.28.3-2.62.31.4-2.0-1.5-2.72.7-1.92.80.5-1.8-0.82.9-2.7-2.7-2.3-2.6-2.52.62.3-2.2
Bone volume2.75.39.1-2.92.51.6-2.2-1.8-2.82.7-2.02.80.1-1.7-0.53.0-2.6-2.7-2.2-2.5-2.32.42.5-2.0
Breakpoint value in progressive ratio session0.81.55.3-0.00.11.1-0.2-1.00.5-0.5-0.1-1.1-2.30.92.3-1.40.81.02.01.01.5-1.6-0.41.9
Number of licking bursts0.10.30.7-0.50.70.9-0.8-0.3-0.70.7-0.70.3-0.8-0.00.8-0.3-0.1-0.40.6-0.2-0.60.10.30.1
Context. condit. distance diff. score0.50.62.61.6-1.0-0.70.80.51.2-0.90.4-1.00.30.30.0-0.71.00.91.10.60.6-0.8-0.20.4
Locomotion velocity, session 10.91.12.3-1.41.31.1-1.5-0.9-1.41.3-0.71.1-0.40.00.40.5-1.2-1.2-0.2-1.1-0.91.01.5-0.6
Locomotion distance, session 10.30.41.6-0.70.81.0-0.9-0.5-0.70.7-0.20.1-1.20.51.3-0.7-0.3-0.50.8-0.2-0.30.00.20.4
Locomotion velocity, session 20.40.51.4-0.91.00.8-1.2-0.6-1.00.9-1.00.7-0.6-0.70.50.5-0.5-0.7-0.4-0.6-0.80.50.4-0.2
Locomotion distance, session 20.40.62.70.00.20.8-0.6-0.3-0.00.10.0-0.5-1.40.71.6-1.40.30.21.60.40.3-0.5-0.20.8
Locomotion velocity, session 30.10.10.50.2-0.3-0.50.20.50.1-0.00.40.20.70.3-0.70.4-0.2-0.1-0.2-0.2-0.20.4-0.5-0.5
Locomotion distance, session 31.61.94.1-0.40.70.0-0.80.1-1.31.5-0.91.61.4-1.3-1.41.6-1.4-1.6-1.6-1.7-2.02.00.3-2.0
Stereotopy head waving bouts, day 30.91.14.80.9-1.0-1.71.01.50.5-0.41.10.22.20.4-2.10.7-0.0-0.1-0.6-0.3-0.40.70.9-1.2
Stereotopy head waving duration, day 30.40.51.80.8-0.9-1.20.91.30.6-0.51.1-0.41.20.7-1.1-0.00.50.30.10.30.00.00.3-0.3
Locomotion velocity, session 70.10.10.50.7-0.3-0.30.10.40.10.10.10.10.50.2-0.3-0.20.0-0.10.5-0.3-0.30.40.5-0.5
Locomotion distance, session 70.20.20.9-0.40.50.8-0.8-0.6-0.50.5-0.50.3-0.9-0.00.9-0.1-0.3-0.30.6-0.3-0.20.1-0.20.1
Stereotopy head waving bouts, day 71.41.64.6-0.10.2-0.7-0.20.6-0.70.9-0.31.41.8-1.2-1.92.2-0.8-1.2-1.8-1.3-1.61.40.9-1.9
Stereotopy head waving duration, day 71.31.64.1-0.70.7-0.2-0.60.2-1.21.2-0.71.51.3-1.2-1.52.0-1.0-1.4-1.8-1.4-1.71.51.3-1.7
Locomotion velocity, session 80.20.31.10.00.40.7-0.8-1.0-0.10.2-0.60.0-0.7-0.01.0-0.5-0.3-0.21.1-0.30.20.00.40.2
Locomotion distance, session 80.40.53.00.7-0.10.5-0.3-0.20.4-0.3-0.1-0.7-1.00.51.3-1.30.70.41.70.40.3-0.7-0.20.7
Degree of sensitization distance1.21.33.80.1-0.20.70.1-0.70.7-0.80.2-1.2-1.80.91.9-1.50.81.11.71.21.5-1.5-0.51.7
Degree of sensitization stereotypy0.70.82.7-0.00.1-0.6-0.10.6-0.60.6-0.21.01.2-0.8-1.31.6-0.5-0.9-1.3-0.9-1.21.00.4-1.4
Conditioned locomotion0.10.10.4-0.20.40.6-0.3-0.6-0.30.4-0.40.2-0.4-0.30.5-0.1-0.4-0.30.1-0.3-0.10.20.20.0
Cocaine response after cond. corrected0.60.93.70.7-0.40.40.4-0.30.8-0.70.3-1.2-1.10.81.4-1.50.80.91.90.91.1-1.10.11.3
Cocaine response after cond. not corrected0.81.24.70.5-0.20.60.2-0.50.8-0.70.1-1.3-1.50.91.7-1.60.91.12.21.01.3-1.30.11.6
Cocaine response before conditioning0.20.30.6-0.70.60.4-0.6-0.3-0.80.6-0.60.6-0.1-0.4-0.00.7-0.5-0.6-0.5-0.5-0.70.50.3-0.4
Saline control response1.52.06.5-1.61.82.5-1.9-1.9-1.51.4-1.60.5-2.5-0.72.5-0.6-0.8-0.80.4-0.5-0.60.1-0.60.8
Bone: connectivity density3.86.111.5-3.42.92.0-2.5-1.5-3.43.0-2.32.9-0.3-2.0-0.32.9-2.5-2.7-2.6-2.4-2.82.32.3-1.8
Bone: cortical apparent density0.30.52.80.7-0.7-1.00.61.70.2-0.20.7-0.21.00.5-1.1-0.40.60.3-0.20.3-0.50.00.3-0.4
Bone: cortical area0.20.40.9-0.20.60.9-0.8-0.9-0.50.7-0.60.5-0.6-0.30.80.1-0.7-0.70.3-0.7-0.50.5-0.3-0.3
Bone: cortical porosity0.60.75.21.0-0.8-0.50.6-0.11.1-0.80.4-0.7-0.1-0.10.3-0.80.60.80.20.61.1-0.7-2.30.5
Bone: cortical porosity0.30.44.30.9-0.5-0.40.3-0.30.7-0.40.1-0.20.3-0.7-0.1-0.3-0.00.2-0.2-0.00.5-0.1-2.1-0.1
Bone: cortical thickness0.50.92.41.6-1.1-0.40.70.81.1-0.80.9-1.1-0.11.00.5-1.21.00.81.50.80.6-0.7-1.40.6
Bone: cortical thickness2.93.58.90.4-0.50.90.50.50.7-1.20.7-2.1-2.81.72.6-2.32.21.92.32.31.5-2.5-2.33.0
Bone: cortical tissue density0.30.42.70.7-0.6-1.00.51.60.1-0.10.6-0.11.10.3-1.2-0.30.50.1-0.30.1-0.70.20.5-0.6
Condit. Reinf. active minus inactive responses1.21.45.11.6-0.8-1.10.31.20.10.4-0.00.72.3-1.2-1.90.7-0.5-0.7-1.0-1.1-1.41.5-0.8-2.0
Condit. Reinf. active-inactive response ratio0.50.52.81.7-0.9-0.60.50.80.6-0.20.1-0.20.9-0.7-0.5-0.30.30.20.0-0.1-0.30.2-1.6-0.6
Condit. Reinf. active responses1.11.44.10.9-0.3-0.80.00.9-0.40.8-0.31.02.0-1.4-1.81.1-0.8-1.0-1.5-1.3-1.61.6-0.2-2.0
Condit. Reinf. inactive responses1.72.23.6-1.61.50.9-1.4-0.9-1.81.7-1.31.80.4-1.6-0.61.6-1.8-1.7-1.9-1.6-1.71.71.3-1.5
Incentive salience index mean2.02.57.10.30.2-0.4-0.60.5-1.01.4-0.71.82.2-1.7-2.11.7-1.5-1.7-1.9-2.0-2.22.30.1-2.7
Condit. Reinf. lever presses2.43.67.3-1.01.10.2-1.2-0.3-1.71.9-1.22.31.7-1.9-1.82.3-2.1-2.2-2.4-2.4-2.42.51.4-2.7
Condit. Reinf. active minus inactive responses0.30.41.0-0.40.50.1-0.5-0.3-0.50.7-0.20.90.5-0.2-0.40.5-0.9-0.9-0.4-1.0-0.70.90.3-1.0
Condit. Reinf. active-inactive response ratio0.00.10.40.2-0.2-0.20.3-0.10.4-0.20.2-0.10.10.1-0.0-0.30.10.20.20.00.4-0.3-0.6-0.0
Condit. Reinf. active responses0.10.10.3-0.40.40.4-0.4-0.3-0.40.40.10.4-0.20.40.3-0.1-0.4-0.50.2-0.4-0.30.30.0-0.2
Condit. Reinf. inactive responses0.30.41.30.0-0.20.30.20.10.3-0.40.7-0.6-0.91.11.0-0.80.50.50.90.70.7-0.7-0.71.0
Condit. Reinf. lever presses0.10.10.40.1-0.3-0.50.40.50.2-0.20.5-0.10.30.6-0.30.10.30.10.20.10.2-0.20.5-0.0
Condit. Reinf. lever reinforcers received0.00.10.1-0.30.20.1-0.2-0.1-0.20.30.20.3-0.10.40.10.1-0.2-0.40.0-0.3-0.10.2-0.1-0.2
Conditioned reinforcement - actives0.00.00.1-0.20.20.3-0.2-0.3-0.10.1-0.20.1-0.20.00.2-0.1-0.1-0.10.0-0.10.0-0.00.20.0
Conditioned reinforcement - inactives0.00.10.5-0.10.0-0.2-0.0-0.00.2-0.2-0.00.30.4-0.3-0.40.70.1-0.2-0.4-0.2-0.00.00.2-0.4
Conditioned locomotion0.10.21.60.0-0.0-0.3-0.10.4-0.0-0.00.40.10.70.8-0.5-0.50.0-0.30.3-0.2-0.30.31.2-0.4
Patch foraging indifference point 0 sec0.10.41.70.5-0.1-0.30.20.1-0.30.70.10.60.8-0.3-0.80.3-0.9-0.7-0.4-0.9-0.71.3-0.3-1.1
Patch foraging indifference point AUC0.51.13.0-1.71.51.6-1.7-1.4-1.31.1-1.20.8-1.3-0.41.10.2-0.8-0.8-0.2-0.6-0.40.21.00.1
Delay disc. indifference point, 0s delay0.80.93.5-0.90.90.5-0.8-0.5-1.31.3-0.60.90.4-0.4-0.30.8-1.2-1.1-0.3-1.1-1.11.01.9-0.7
Delay disc. indifference point, 16s delay0.71.02.01.2-1.0-0.61.00.61.1-1.10.8-1.3-0.11.00.3-1.01.41.11.01.11.0-1.3-1.21.0
Delay disc. indifference point, 2s delay0.40.51.30.8-0.9-1.11.01.00.6-0.60.6-0.20.9-0.4-1.20.60.40.5-0.90.20.10.1-0.4-0.3
Delay disc. indifference point, 24s delay0.10.21.21.1-0.6-0.50.40.20.5-0.30.0-0.00.7-0.7-0.50.20.20.2-0.3-0.20.00.1-0.3-0.5
Delay disc. indifference point, 4s delay0.80.92.9-0.80.5-0.2-0.30.4-1.10.9-0.31.00.9-0.9-1.21.4-0.8-0.8-1.7-0.9-1.41.10.3-1.1
Delay disc. indifference point, 8s delay0.20.41.31.0-0.7-0.90.51.0-0.00.10.50.11.2-0.3-0.90.70.0-0.2-0.5-0.1-0.70.3-0.2-0.7
Indifference point function ln k0.51.65.32.1-1.6-2.11.72.11.0-0.71.6-0.52.30.7-2.1-0.00.40.3-0.10.1-0.20.50.1-1.0
Indifference point function log k0.51.65.32.1-1.6-2.11.72.11.0-0.71.6-0.52.30.7-2.1-0.00.40.3-0.10.1-0.20.50.1-1.0
Patch foraging total patch changes 0 sec0.10.30.80.8-0.4-0.60.50.50.10.20.60.20.80.1-0.7-0.2-0.5-0.30.0-0.4-0.30.9-0.7-0.8
Patch foraging total patch changes 12 sec1.41.83.9-1.31.71.5-2.0-1.4-1.71.8-1.51.5-0.7-1.20.70.5-1.5-1.6-0.4-1.5-1.51.40.3-0.9
Patch foraging total patch changes 18 sec1.22.75.1-2.32.32.1-2.2-1.7-2.32.2-1.61.8-1.2-1.01.10.7-1.8-1.9-0.6-1.7-1.51.30.4-0.7
Patch foraging total patch changes 24 sec0.72.33.5-1.61.71.4-1.7-1.5-1.81.9-1.61.8-0.2-1.40.01.1-1.8-1.8-1.2-1.7-1.71.80.7-1.3
Patch foraging total patch changes 6 sec0.20.40.8-0.80.80.9-0.8-0.6-0.90.9-0.50.5-0.7-0.30.60.2-0.6-0.6-0.4-0.5-0.40.4-0.5-0.1
Patch foraging time to switch 0 sec0.10.20.6-0.40.40.6-0.5-0.6-0.30.2-0.60.2-0.7-0.70.60.2-0.1-0.1-0.2-0.1-0.2-0.2-0.80.2
Patch foraging water rate 0 sec0.10.21.00.3-0.3-0.20.50.20.3-0.20.7-0.4-0.21.00.2-0.90.20.30.70.30.6-0.2-0.20.3
Patch foraging water rate 12 sec0.20.93.60.5-0.8-1.60.81.90.2-0.31.20.11.80.8-1.80.50.3-0.0-0.5-0.0-0.50.40.3-0.8
Patch foraging water rate 18 sec1.02.36.5-0.40.2-1.1-0.11.0-0.90.90.21.62.4-0.4-2.51.9-1.1-1.5-2.0-1.5-1.82.01.5-2.4
Patch foraging water rate 24 sec0.70.94.20.7-0.4-1.20.31.2-0.10.20.50.52.00.0-1.90.8-0.5-0.6-0.8-0.7-1.01.20.7-1.5
Patch foraging water rate 6 sec1.72.56.0-2.42.32.1-2.0-1.6-2.22.0-1.61.5-1.1-0.50.90.9-1.6-1.7-0.6-1.4-1.41.21.5-0.4
Seeking ratio, delayed vs. immediate footshock1.31.84.41.7-1.7-1.51.72.11.1-1.21.8-1.50.81.5-0.6-1.31.41.30.81.40.4-0.8-1.50.8
Distance traveled before self-admin0.40.81.91.0-1.2-1.21.20.91.2-1.10.9-0.70.60.0-0.9-0.40.81.0-0.60.70.8-0.6-1.40.1
Distance traveled after self-admin0.30.61.60.5-1.0-1.30.90.91.2-1.30.9-0.40.60.5-0.7-0.21.10.6-0.10.70.7-0.8-0.00.0
Extensor digitorum longus weight0.31.14.30.7-0.50.30.3-0.51.0-0.90.3-1.0-1.20.61.5-1.30.81.01.61.01.3-1.3-2.11.2
Bone: elastic displacement0.40.51.70.9-0.6-1.00.41.00.4-0.10.8-0.01.30.8-1.0-0.1-0.0-0.20.2-0.3-0.30.51.3-0.8
Bone: elastic work1.11.43.51.7-1.5-1.31.21.41.4-1.11.7-1.20.71.9-0.3-1.31.00.91.60.80.8-0.6-0.00.3
Bone: endosteal estimation0.40.93.1-1.11.21.6-1.1-1.5-0.80.7-1.00.3-1.7-0.01.8-0.6-0.4-0.41.0-0.2-0.1-0.10.70.6
Bone: endosteal perimeter1.02.54.6-1.31.81.8-1.9-2.1-1.61.9-1.91.7-0.6-1.70.81.1-2.0-1.9-0.7-1.9-1.41.60.4-1.2
Epididymis fat weight0.10.31.0-0.10.40.3-1.0-0.7-0.20.4-0.50.60.1-0.70.20.4-0.7-0.7-0.1-0.8-0.40.5-0.0-0.6
Delta time in closed arm before/after self-admin0.50.52.21.1-0.9-0.90.81.00.5-0.40.7-0.30.9-0.4-0.80.30.40.3-0.50.3-0.1-0.0-1.5-0.3
Delta time in open arm before/after self-admin1.72.05.9-1.61.72.4-1.8-2.4-1.31.3-1.60.4-2.30.02.4-0.8-1.0-0.61.2-0.60.00.01.00.8
Diff in mean of infusions in LGA sessions0.10.30.8-0.60.60.8-0.7-0.7-0.60.6-0.60.2-0.9-0.50.80.2-0.3-0.2-0.0-0.2-0.1-0.0-0.40.3
Delay discount exponential model param0.30.41.1-0.40.30.6-0.3-0.70.2-0.2-0.1-0.3-1.00.81.0-1.00.00.21.00.30.7-0.40.30.7
Extinction: sum of active levers before priming1.32.05.72.1-1.8-2.12.02.41.1-1.12.0-1.11.81.8-1.6-0.41.00.80.80.80.10.10.3-0.2
Active lever presses in extinction session 61.11.14.20.4-0.5-1.40.41.00.1-0.00.50.82.0-0.3-2.00.7-0.2-0.7-1.2-0.8-0.90.81.6-1.7
Bone: final force0.20.31.5-0.30.40.8-0.6-0.9-0.10.1-0.2-0.1-1.10.21.2-0.6-0.1-0.00.80.10.4-0.2-0.40.6
Bone: final moment0.20.31.3-0.20.30.7-0.5-0.7-0.10.1-0.1-0.2-0.90.31.1-0.7-0.1-0.00.90.20.3-0.2-0.40.6
Food consumed during 24 hour testing period2.44.812.3-3.23.13.5-2.8-3.0-2.72.3-2.81.5-2.9-1.32.60.5-1.7-1.7-0.2-1.2-1.20.71.80.4
Glucose0.10.20.70.2-0.10.1-0.2-0.70.5-0.40.1-0.4-0.50.50.7-0.8-0.00.30.90.30.8-0.3-0.20.5
Heart weight0.61.04.11.3-1.3-1.50.92.00.6-0.81.1-0.71.00.4-1.1-0.21.20.8-0.40.9-0.1-0.4-1.80.0
Delay discount hyperbolic model param0.30.41.4-0.40.30.6-0.3-0.80.3-0.3-0.1-0.4-1.10.81.1-1.00.10.31.20.40.9-0.50.20.8
Intermittent access intake day 1-15 change0.63.35.0-2.22.21.7-2.1-1.8-2.02.0-2.22.2-0.2-2.00.12.0-1.8-2.0-1.6-2.0-1.71.61.4-1.4
Intermittent access intake escalation0.42.13.1-1.71.71.3-1.7-1.4-1.61.5-1.81.7-0.1-1.50.11.6-1.4-1.6-1.2-1.6-1.41.21.2-1.2
Intermittent access intake escalation 21.32.23.3-1.81.81.4-1.8-1.4-1.61.5-1.71.7-0.2-1.20.21.4-1.5-1.7-1.0-1.5-1.41.31.8-1.2
Intermitt. access day 1 inactive lever presses0.11.03.2-0.50.6-0.2-0.4-0.0-0.91.0-0.31.11.2-0.4-1.30.8-1.1-1.2-1.0-1.2-1.21.31.8-1.4
Intermitt. access day 15 inactive lever presses0.10.61.30.6-0.7-0.40.70.41.0-1.00.8-0.8-0.11.10.1-1.00.90.91.10.81.0-0.8-0.30.6
Intermitt. access escalation Index0.10.51.70.7-0.7-1.00.71.30.2-0.20.9-0.21.30.9-1.1-0.10.20.10.20.0-0.30.40.3-0.5
Intermittent access day 1 total infusions0.92.75.11.9-1.8-1.41.91.61.8-1.82.0-1.90.32.3-0.1-1.91.81.72.01.71.6-1.4-0.61.2
Intermittent access day 15 total infusions0.10.30.60.7-0.7-0.80.80.70.7-0.70.7-0.40.50.6-0.5-0.20.70.50.40.50.4-0.4-0.40.1
Intermittent access terminal intake (last 3 days)0.20.40.70.7-0.7-0.70.80.60.8-0.80.7-0.50.50.7-0.5-0.30.70.50.60.50.5-0.4-0.10.1
Intermittent access total infusions0.80.91.61.0-1.0-0.91.10.81.2-1.21.1-1.00.21.3-0.1-1.11.11.01.11.01.0-0.9-0.20.6
Intermittent access day 1 locomotion1.22.36.91.7-1.6-1.61.61.91.3-1.32.0-1.51.02.6-0.6-2.01.41.22.01.20.8-0.70.90.6
Intermittent access day 15 total locomotion0.41.53.41.1-1.1-0.71.10.81.4-1.41.2-1.4-0.21.80.4-1.61.41.31.81.31.3-1.3-0.11.2
Intermittent access total locomotion2.32.86.71.5-1.5-0.91.51.11.7-1.81.7-2.0-0.32.60.6-2.41.81.72.51.81.7-1.70.11.6
Intermittent access standard deviation0.31.42.5-1.31.20.7-1.3-0.9-1.11.1-1.31.60.3-1.4-0.41.6-1.2-1.3-1.4-1.4-1.21.21.1-1.3
Left kidney weight0.64.79.2-2.22.62.4-2.7-2.5-2.42.5-2.82.4-1.2-3.01.01.7-2.2-2.4-2.0-2.2-2.11.6-0.5-1.3
Right kidney weight0.53.57.0-1.72.42.6-2.5-2.6-1.92.2-2.51.7-1.7-2.31.80.9-1.9-1.9-0.8-1.8-1.51.2-0.2-0.6
Cocaine induced anxiety0.20.52.30.7-0.6-1.10.71.10.2-0.10.70.21.50.1-1.50.7-0.1-0.1-0.6-0.2-0.40.70.1-0.9
Post-drug Anxiety0.20.30.80.6-0.7-0.80.60.90.5-0.50.7-0.30.60.1-0.60.20.50.4-0.30.30.2-0.2-0.6-0.1
Baseline Anxiety0.30.52.0-0.20.10.7-0.2-0.60.1-0.2-0.4-0.5-1.4-0.51.4-0.30.50.50.20.50.7-1.0-1.11.1
Tail length2.111.116.1-4.03.93.1-3.8-3.5-3.73.6-3.94.0-0.6-3.60.23.9-3.7-3.7-3.0-3.7-3.02.92.3-2.5
Length with tail1.25.311.2-2.42.72.5-3.0-3.3-2.12.2-3.12.5-0.8-3.10.92.1-2.6-2.4-1.9-2.5-1.51.71.2-1.4
Length without tail0.10.41.70.30.00.5-0.4-1.10.6-0.5-0.3-0.5-0.90.01.3-1.20.20.30.90.30.9-0.7-0.10.7
Times rat made contact with spout0.00.00.4-0.20.1-0.0-0.10.3-0.20.10.0-0.1-0.10.2-0.00.10.20.00.10.2-0.2-0.10.60.1
Lifetime Intake0.40.50.90.8-0.8-0.70.90.61.0-0.90.9-0.70.31.0-0.2-0.70.80.70.80.70.7-0.7-0.00.4
Liver weight, left0.50.81.8-0.80.90.7-1.2-1.3-0.81.0-1.01.00.1-0.70.10.5-1.3-1.1-0.4-1.2-0.71.01.3-0.8
Liver weight, right0.91.63.6-0.91.30.9-1.6-1.4-1.21.4-1.11.30.2-0.80.00.5-1.9-1.7-0.5-1.6-1.31.61.7-1.2
Locomotor activity1.21.95.5-0.0-0.30.50.40.20.6-0.70.9-1.5-1.92.01.9-2.31.21.22.11.51.4-1.6-0.62.1
Locomotor testing distance0.82.04.5-0.1-0.30.50.60.20.7-0.91.0-1.6-1.92.01.8-2.11.31.42.01.61.5-1.7-1.12.1
Locomotor testing rearing0.31.24.9-1.51.42.0-1.3-1.1-1.20.9-0.90.2-2.2-0.02.1-0.5-0.1-0.40.50.0-0.3-0.40.01.0
Locomotion in novel chamber1.11.54.30.6-0.50.40.50.30.6-0.70.6-1.5-1.61.41.7-2.11.11.11.81.31.1-1.4-1.21.9
Locomotion in novel chamber post-restriction0.20.76.7-1.00.80.4-0.7-0.1-0.70.60.10.40.11.4-0.1-0.2-0.7-0.80.7-0.6-0.60.72.6-0.3
Fecal boli incidents, locomotor time 10.92.55.8-1.71.81.6-1.8-2.0-1.41.6-1.91.6-0.3-2.40.21.2-1.9-1.6-2.2-1.6-1.11.3-0.0-1.1
Change in fecal boli incidents, locomotor task0.70.82.0-0.40.4-0.3-0.20.8-1.00.8-0.00.91.0-0.0-1.21.3-0.6-0.9-0.8-0.8-1.41.21.2-1.1
Time >=10cm from walls, locomotor time 10.20.33.0-0.70.40.3-0.1-0.0-0.20.0-0.40.1-0.5-0.60.10.90.30.1-0.90.2-0.0-0.3-1.70.3
Bouts of movement, locomotor time 10.30.41.60.2-0.2-0.60.20.40.2-0.10.10.51.0-0.6-1.11.3-0.1-0.3-1.1-0.3-0.20.30.2-0.9
Total resting periods, locomotor time 10.50.62.30.5-0.4-1.00.40.70.3-0.30.30.51.4-0.5-1.51.30.0-0.3-1.2-0.4-0.40.50.3-1.1
Rest time, locomotor task time 10.20.31.20.7-0.6-1.00.50.60.5-0.30.40.21.1-0.4-1.10.40.1-0.1-0.5-0.2-0.10.3-0.2-0.9
Distance moved, locomotor task time 10.41.03.70.1-0.20.40.2-0.00.5-0.70.4-1.1-1.11.51.3-1.40.91.01.91.11.0-1.2-0.21.4
Vertical activity count, locomotor time 10.31.96.0-1.81.72.3-1.7-2.1-1.10.8-1.70.3-2.5-1.42.40.0-0.6-0.30.00.00.2-0.6-1.11.2
Time >=10cm from walls, locomotor time 20.30.92.40.8-1.1-0.81.10.31.3-1.30.8-1.00.00.70.0-0.51.11.30.51.01.5-1.1-0.90.9
Bouts of movement, locomotor time 20.10.41.60.7-0.8-1.00.81.30.5-0.60.8-0.30.70.3-0.90.20.70.4-0.20.40.1-0.20.2-0.2
Total resting periods, locomotor time 20.00.10.60.3-0.4-0.60.50.80.3-0.40.4-0.10.3-0.1-0.50.30.50.3-0.30.30.1-0.2-0.0-0.1
Rest time, locomotor task time 20.20.31.1-0.80.70.7-0.6-0.6-0.60.5-0.70.5-0.4-1.10.20.7-0.4-0.3-0.7-0.3-0.30.3-0.3-0.1
Distance moved, locomotor task time 21.92.54.11.8-1.7-1.31.51.12.0-1.91.7-1.80.12.00.3-1.51.81.72.01.61.9-1.8-0.51.2
Vertical activity count, locomotor time 20.40.94.0-0.60.81.4-1.1-1.4-0.30.2-0.9-0.1-1.6-0.42.0-0.90.1-0.20.80.20.5-0.9-0.71.0
Light reinforcement 12.913.327.3-4.85.05.2-4.8-5.0-4.44.2-4.63.2-3.5-3.23.31.4-3.9-3.5-1.5-2.9-2.62.21.6-0.5
Light reinforcement 23.98.820.7-4.24.14.3-4.0-4.6-3.23.0-3.92.6-3.1-2.72.81.4-3.0-2.6-1.2-2.3-1.51.41.7-0.2
Bone: marrow area0.40.93.3-1.11.21.6-1.1-1.5-0.80.7-0.90.2-1.7-0.01.8-0.6-0.4-0.41.0-0.2-0.0-0.20.50.7
Bone: maximum diameter0.40.71.70.10.50.4-0.7-0.8-0.50.9-0.91.00.5-1.1-0.20.9-1.2-1.1-0.4-1.3-1.01.30.1-1.3
Bone: maximum force0.10.21.0-0.00.10.5-0.3-0.80.1-0.1-0.0-0.2-0.70.41.0-0.6-0.10.11.00.10.5-0.2-0.00.5
Bone: maximum moment0.10.21.20.10.10.4-0.3-0.60.1-0.00.0-0.2-0.60.50.9-0.7-0.10.01.10.10.3-0.10.10.4
Mean time between licks in bursts0.10.31.30.00.40.2-0.60.2-0.70.8-0.40.50.4-0.3-0.3-0.1-0.4-0.7-0.1-0.7-1.20.81.1-0.7
Mean num. licks in bursts0.10.41.30.4-0.7-1.00.80.80.4-0.50.7-0.21.00.3-1.20.50.20.3-0.60.20.30.10.7-0.2
Cd content in liver1.61.75.42.3-1.6-1.11.31.71.5-1.21.2-1.50.40.7-0.2-2.01.41.21.11.20.5-0.9-1.70.6
Co content in liver2.02.46.52.4-2.1-2.62.02.51.5-1.21.9-0.82.51.0-2.2-0.50.80.70.30.40.10.2-0.7-0.8
Cu content in liver0.30.42.20.8-0.6-0.50.40.50.6-0.40.6-0.5-0.00.50.2-0.90.40.40.80.40.3-0.3-1.50.2
Fe content in liver1.31.64.3-0.70.4-0.8-0.3-0.3-0.50.7-0.41.51.9-1.0-1.92.1-1.4-1.1-1.9-1.4-0.81.51.5-1.9
K content in liver1.11.14.30.9-1.0-1.31.21.11.0-0.91.6-0.90.72.1-0.4-0.90.60.61.70.60.7-0.31.00.2
Mg content in liver0.60.72.80.7-0.8-1.21.11.10.5-0.31.5-0.21.11.7-0.8-0.6-0.1-0.01.1-0.00.10.41.0-0.4
Mn content in liver0.40.40.9-0.50.80.8-0.9-0.6-0.70.9-0.50.6-0.4-0.30.6-0.4-0.7-0.90.3-0.7-0.80.6-0.2-0.4
Na content in liver0.10.10.7-0.60.30.10.0-0.4-0.10.0-0.00.2-0.10.20.00.3-0.2-0.10.1-0.10.2-0.00.9-0.0
Rb content in liver0.20.20.5-0.50.50.3-0.3-0.2-0.60.6-0.30.5-0.1-0.10.10.2-0.7-0.60.0-0.5-0.60.50.3-0.4
Se content in liver1.61.94.2-0.80.8-0.1-1.0-1.1-0.81.1-0.71.81.4-1.2-1.22.0-2.0-1.7-1.6-1.9-1.01.91.0-2.1
Sr content in liver0.70.61.61.1-0.9-0.50.90.90.8-0.71.1-0.90.31.2-0.0-1.20.70.61.20.60.5-0.5-0.30.4
Zn content in liver1.01.22.31.5-1.4-1.21.51.31.2-1.11.4-1.00.51.1-0.3-0.81.01.00.80.90.8-0.7-1.50.4
Bone: minimum diameter1.12.14.7-1.71.92.1-2.0-2.2-1.61.6-1.81.2-1.3-1.11.30.7-1.4-1.4-0.2-1.3-1.00.91.1-0.3
Time in familiar zone, hab. session 10.70.72.0-0.50.70.5-0.7-0.3-1.01.0-1.00.90.2-1.4-0.41.2-0.7-0.8-1.2-0.9-1.20.90.3-0.8
Time in novel zone, hab. session 11.41.63.90.8-1.3-1.21.31.31.3-1.51.7-1.40.22.0-0.2-1.01.41.51.11.51.5-1.4-0.11.1
Total zone transitions, hab. session 10.30.41.7-0.90.71.0-0.7-0.7-0.40.2-0.3-0.1-1.30.21.2-0.30.00.00.50.20.2-0.5-0.30.7
Total locomotion distance, hab. session 10.30.41.0-0.60.30.6-0.3-0.2-0.2-0.00.1-0.4-1.01.01.0-1.00.30.21.00.40.4-0.50.40.8
Locomotion velocity, hab. session 10.30.51.6-0.80.61.0-0.6-0.6-0.40.3-0.1-0.2-1.20.81.3-1.1-0.0-0.11.10.20.2-0.30.20.8
Time in familiar zone, hab. session 21.11.32.1-1.21.41.2-1.4-1.1-1.41.4-1.31.1-0.4-1.20.40.6-1.2-1.3-0.7-1.1-1.31.01.2-0.6
Time in novel zone, hab. session 23.03.34.91.9-2.0-1.41.91.52.1-2.11.7-2.1-0.11.90.2-1.52.22.21.82.12.0-2.0-1.81.6
Total zone transitions, hab. session 20.50.71.7-1.21.11.1-1.1-0.3-1.31.1-0.50.7-0.90.20.8-0.0-0.7-1.00.3-0.6-1.00.70.5-0.2
Total locomotion distance, hab. session 20.40.51.7-0.80.81.1-0.8-0.6-0.60.6-0.20.1-1.20.61.3-1.0-0.3-0.41.0-0.1-0.20.0-0.10.4
Locomotion velocity, hab. session 20.40.51.8-0.90.91.1-0.8-0.8-0.70.6-0.30.1-1.30.51.4-0.9-0.4-0.40.8-0.1-0.10.0-0.20.4
Novel to familiar place preference ratio0.91.22.10.7-0.9-0.51.00.90.9-1.11.0-1.4-0.41.40.5-1.21.41.31.31.41.0-1.3-0.31.4
Novelty place preference1.11.42.90.6-0.8-0.31.00.81.0-1.20.9-1.6-0.71.50.8-1.41.51.51.51.61.2-1.6-0.51.7
Time in novel zone, NPP test1.51.83.30.8-1.2-0.81.31.21.2-1.51.3-1.7-0.41.80.3-1.31.71.61.41.81.4-1.6-0.31.6
Total zone transitions, NPP test0.81.12.6-1.11.41.5-1.6-1.3-1.31.4-1.11.0-1.0-0.61.10.0-1.2-1.20.1-1.1-1.00.90.0-0.4
Total locomotion distance, NPP test0.10.20.4-0.40.50.6-0.7-0.3-0.50.5-0.20.3-0.60.40.7-0.4-0.3-0.40.6-0.3-0.40.2-0.1-0.0
Locomotion velocity, NPP test0.30.51.2-0.50.81.0-1.1-0.9-0.60.8-0.60.5-0.8-0.11.0-0.5-0.6-0.70.6-0.6-0.50.4-0.4-0.2
Intraocular pressure1.42.25.12.3-2.1-2.01.92.21.7-1.51.8-1.31.51.0-1.3-0.91.51.30.41.10.8-0.9-1.60.2
Delta distance traveled before/after self-admin0.10.21.4-0.40.30.1-0.40.1-0.30.20.10.1-0.10.70.3-0.2-0.1-0.40.6-0.0-0.30.01.20.1
Delta ambulatory time before/after self-admin0.50.84.7-1.21.10.6-1.2-0.4-1.10.9-0.60.9-0.00.20.20.3-0.7-1.30.1-0.8-1.10.72.2-0.6
Parametrial fat weight0.30.82.6-0.71.11.4-1.6-1.6-0.50.7-1.20.6-1.0-1.01.20.1-0.7-0.70.0-0.7-0.20.1-0.5-0.0
Pavlov. Cond. lever latency0.40.41.4-0.10.00.50.10.10.1-0.30.0-0.7-1.20.51.1-1.00.80.60.80.80.4-0.9-0.61.1
Pavlov. Cond. magazine entry latency0.40.51.90.6-0.8-1.20.71.00.6-0.50.8-0.21.40.5-1.40.30.20.2-0.20.10.10.30.3-0.5
Pavlov. Cond. change in total contacts1.01.12.4-0.40.5-0.0-0.6-0.3-0.70.9-0.51.21.3-0.7-1.21.3-1.4-1.3-1.1-1.4-1.11.61.2-1.6
Pavlov. Cond. index score0.40.52.70.6-0.6-1.10.40.70.4-0.20.60.21.70.2-1.50.6-0.3-0.2-0.3-0.4-0.20.70.7-1.0
Pavlov. Cond. latency score0.30.31.60.4-0.3-0.70.10.30.20.00.30.41.3-0.1-1.20.6-0.5-0.4-0.4-0.6-0.30.80.6-1.0
Pavlov. Cond. lever contacts0.40.42.10.4-0.5-0.90.40.50.3-0.10.50.41.40.0-1.40.9-0.4-0.2-0.5-0.5-0.10.70.4-1.0
Pavlov. Cond. magazine entry number0.91.13.6-1.21.31.8-1.3-1.4-1.11.0-1.40.4-1.9-0.81.8-0.1-0.4-0.50.1-0.3-0.4-0.2-0.10.6
Pavlov. Cond. intertrial magazine entries0.91.12.90.30.3-0.2-0.4-0.4-0.61.0-0.61.21.2-1.4-0.91.2-1.4-1.3-1.2-1.5-1.21.6-0.1-1.7
Pavlov. Cond. lever-magazine prob. diff.0.50.73.00.9-0.9-1.40.70.90.8-0.50.9-0.11.70.5-1.60.3-0.10.1-0.1-0.20.10.50.7-0.9
Pavlov. Cond. response bias0.81.04.30.7-1.0-1.61.01.30.6-0.51.10.12.10.5-2.10.7-0.10.0-0.6-0.2-0.10.60.5-1.1
Pavlov. Cond. lever latency0.10.21.00.7-0.4-0.10.3-0.20.6-0.5-0.0-0.5-0.0-0.30.2-0.20.20.50.20.30.6-0.4-1.00.3
Pavlov. Cond. magazine entry latency0.10.10.4-0.10.30.2-0.1-0.3-0.30.4-0.50.3-0.1-0.6-0.00.6-0.2-0.3-0.4-0.4-0.40.30.4-0.3
Pavlov. Cond. change in total contacts0.10.31.0-0.30.0-0.50.00.7-0.40.40.30.60.80.1-1.00.7-0.3-0.5-0.8-0.5-0.70.60.5-0.8
Pavlov. Cond. index score0.10.20.9-0.40.3-0.2-0.10.2-0.50.50.00.50.3-0.0-0.50.7-0.3-0.5-0.6-0.5-0.60.50.9-0.5
Pavlov. Cond. latency score0.20.31.4-0.50.4-0.1-0.20.1-0.60.6-0.10.60.3-0.1-0.50.8-0.4-0.6-0.6-0.6-0.70.61.2-0.6
Pavlov. Cond. lever contacts0.10.10.5-0.70.50.2-0.30.1-0.60.5-0.10.4-0.20.10.00.2-0.2-0.4-0.2-0.2-0.50.20.7-0.1
Pavlov. Cond. magazine entry number0.10.10.50.2-0.20.1-0.00.10.3-0.40.2-0.5-0.20.40.3-0.70.40.40.50.50.3-0.4-0.20.5
Pavlov. Cond. intertrial magazine entries0.81.84.2-1.71.81.8-2.1-1.5-1.71.6-1.51.3-0.9-1.10.80.5-1.5-1.5-0.9-1.3-1.31.10.4-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.9-0.30.1-0.30.00.3-0.40.40.10.40.40.0-0.60.6-0.2-0.4-0.5-0.4-0.50.40.9-0.5
Pavlov. Cond. response bias0.00.00.1-0.30.2-0.1-0.10.2-0.30.20.20.2-0.10.2-0.10.2-0.0-0.2-0.1-0.1-0.20.10.3-0.1
Time in closed arm before self-admin0.81.35.7-1.41.20.3-0.9-0.2-1.21.1-0.71.20.6-0.2-0.90.7-1.2-1.4-1.1-1.2-1.31.52.4-1.2
Time in closed arm after self-admin0.70.83.6-0.10.3-0.2-0.10.2-0.70.7-0.40.70.9-1.5-1.11.4-0.8-0.7-1.9-0.7-0.91.1-0.7-1.0
Time in open arm before self-admin0.60.73.51.2-1.1-1.11.00.90.9-0.90.7-0.40.7-0.5-0.60.31.00.6-0.40.70.3-0.7-1.90.0
Time in open arm after self-admin0.50.52.30.4-0.50.10.3-0.20.6-0.60.3-0.7-0.61.10.8-1.00.70.71.50.60.8-1.0-0.20.9
Bone: periosteal estimation0.51.23.4-1.11.41.8-1.4-1.7-1.11.1-1.30.7-1.6-0.41.7-0.1-0.8-0.90.7-0.7-0.50.40.30.2
Bone: periosteal perimeter0.81.62.8-0.61.41.4-1.5-1.5-1.31.7-1.61.4-0.3-1.40.60.8-1.6-1.7-0.4-1.7-1.51.50.0-1.1
Bone: post-yield work0.20.41.6-0.90.71.0-0.5-1.1-0.40.2-0.7-0.0-1.3-0.21.1-0.1-0.10.10.00.20.3-0.40.10.8
Progressive ratio test 1 active lever presses0.81.32.41.2-1.3-0.91.20.91.4-1.31.3-1.30.01.50.1-1.31.21.21.51.31.2-1.1-0.51.0
Progressive ratio test 1 breakpoint0.81.42.31.3-1.3-1.01.30.91.4-1.41.3-1.30.01.50.1-1.31.31.31.41.31.3-1.2-0.61.0
Progressive ratio test 1 inactive lever presses0.10.30.60.6-0.6-0.70.70.40.8-0.70.7-0.40.50.7-0.5-0.40.40.40.40.40.6-0.40.30.1
Progressive ratio test 2 active lever presses0.71.01.71.1-1.2-0.81.10.61.3-1.30.9-1.1-0.10.70.1-0.91.21.20.71.21.1-1.2-1.30.8
Progressive ratio test 2 breakpoint0.91.11.91.1-1.2-0.81.20.71.4-1.40.9-1.1-0.10.70.1-0.91.31.20.81.21.2-1.3-1.30.9
Progressive ratio test 2 inactive lever presses0.51.72.91.5-1.5-1.31.51.21.7-1.71.4-1.30.31.1-0.3-1.11.61.41.01.41.3-1.4-1.20.8
Incentive Sensitization - Responses0.10.33.20.3-0.3-0.10.3-0.10.5-0.5-0.1-0.2-0.3-0.60.20.30.50.5-0.20.40.4-0.6-1.80.3
Incentive Sensitization - Breakpoint0.10.22.60.2-0.20.00.2-0.10.4-0.4-0.2-0.1-0.3-0.60.20.30.40.4-0.30.30.3-0.6-1.60.2
Sum of active levers in priming session hrs 5-60.40.41.50.2-0.10.30.10.10.1-0.20.3-0.7-0.80.91.0-1.10.40.51.20.60.5-0.60.60.9
Progressive ratio0.30.83.0-0.80.91.3-0.8-1.2-0.70.6-1.20.3-1.7-1.01.40.5-0.4-0.1-0.2-0.20.0-0.1-1.10.5
Food seeking constrained by brief footshock1.92.44.2-1.82.01.6-2.0-1.7-1.71.9-1.91.8-0.6-1.50.31.2-1.8-1.8-1.1-1.8-1.31.51.0-1.1
Seeking ratio, punishment vs. effort0.30.72.9-0.80.80.4-1.0-0.6-0.60.8-0.61.00.7-0.3-0.50.4-1.0-1.2-0.5-1.1-0.81.01.7-1.0
Retroperitoneal fat weight0.20.93.8-0.30.91.4-1.9-1.6-0.40.6-1.00.4-1.3-0.61.8-0.5-0.8-0.70.8-0.7-0.10.2-0.40.1
Reaction time number correct0.20.82.81.3-1.0-1.51.31.40.7-0.50.9-0.11.70.3-1.70.60.30.2-0.20.0-0.10.4-0.3-0.8
Reaction time mean minus median0.10.51.71.2-0.9-0.90.80.21.3-1.20.4-0.60.7-0.0-0.50.40.90.70.10.50.9-0.7-0.40.1
Reaction time mean minus median AUC0.21.03.11.7-1.3-1.31.10.61.8-1.60.8-1.00.80.5-0.6-0.31.11.00.60.81.2-0.8-0.30.2
Reaction time num false alarms0.81.34.02.0-1.5-1.01.41.21.3-1.01.0-1.20.30.40.0-1.21.21.10.81.00.6-0.8-2.00.5
Reaction time num false alarms AUC0.51.13.41.8-1.5-1.31.41.51.1-0.91.1-0.90.70.4-0.6-0.81.00.90.40.80.3-0.4-1.50.1
Reaction time trials correct on left0.20.82.81.3-1.0-1.51.31.40.7-0.50.9-0.11.70.3-1.70.60.30.2-0.20.0-0.10.4-0.3-0.8
Reaction time trials on left0.20.82.61.4-1.1-1.51.41.40.8-0.61.0-0.21.60.4-1.60.50.40.3-0.10.1-0.00.3-0.3-0.7
Reaction time mean1.53.47.42.7-2.4-2.12.01.52.6-2.51.7-2.10.91.2-0.5-1.32.22.11.21.81.9-1.9-0.61.1
Reaction time mean AUC1.33.26.92.6-2.4-2.01.91.52.6-2.41.7-2.10.91.3-0.5-1.32.12.01.31.71.9-1.8-0.51.0
Median of all reaction times2.33.67.72.8-2.5-2.22.11.82.6-2.41.9-2.21.01.4-0.6-1.62.22.11.31.81.9-1.8-0.51.1
Reaction time omissions1.11.83.71.8-1.5-0.71.20.31.9-1.80.5-1.6-0.5-0.40.6-0.21.61.70.61.41.7-1.8-1.71.3
Reaction time false alarm rate0.20.30.80.9-0.8-0.40.60.60.5-0.40.5-0.60.00.20.1-0.80.60.50.40.50.2-0.4-0.90.3
Reaction time premature initiation rate4.16.410.1-2.93.22.6-3.1-2.6-3.23.1-2.92.9-0.7-2.20.61.9-2.8-3.0-1.6-2.8-2.62.22.2-1.8
Reaction time premature initiations1.34.06.3-2.02.31.7-2.1-1.7-2.52.5-2.22.40.0-1.7-0.11.9-2.2-2.5-1.5-2.4-2.32.11.8-1.8
Std. dev. reaction times0.30.92.71.5-1.2-1.00.90.31.6-1.60.5-1.00.5-0.0-0.30.11.31.10.30.81.2-1.2-0.40.5
Reaction time trials completed0.20.82.61.4-1.1-1.51.41.40.8-0.61.0-0.21.60.4-1.60.50.40.3-0.10.1-0.00.3-0.3-0.7
Reaction time trials AUC0.30.92.31.4-1.2-1.51.51.50.9-0.71.1-0.31.50.5-1.50.30.60.50.00.30.10.1-0.6-0.5
Run reversals in cocaine runway, females2.02.24.81.0-1.00.00.8-0.41.5-1.40.8-1.7-1.61.01.9-1.71.31.72.11.62.2-1.9-1.42.0
Run reversals in cocaine runway, males0.50.51.60.3-0.7-0.60.70.81.0-1.00.6-0.5-0.1-0.2-0.30.41.10.9-0.40.90.7-0.8-1.30.4
Latency to leave start box in cocaine runway1.11.53.20.6-0.50.30.3-0.41.2-1.30.3-1.3-1.40.61.6-1.51.21.31.21.41.7-1.7-1.81.7
Latency to leave start box in cocaine runway, F1.41.73.50.9-1.1-0.41.00.41.5-1.51.2-1.7-0.71.60.9-1.41.31.61.51.71.9-1.5-1.01.6
Latency to leave start box in cocaine runway, M0.70.72.2-0.50.81.2-1.1-1.4-0.30.2-1.10.2-1.2-0.91.5-0.5-0.1-0.30.1-0.10.1-0.5-1.20.4
Std. dev. time between licks in bursts0.61.12.1-1.11.31.3-1.4-1.0-1.41.4-1.51.1-0.6-1.10.50.5-1.0-1.2-0.6-1.1-1.30.90.4-0.6
Total sessions with >9 infusions1.41.84.21.6-1.6-2.11.71.91.2-1.11.9-0.81.91.9-1.8-0.70.80.70.90.60.4-0.01.0-0.4
Short access day 1 total inactive lever presses0.10.30.90.1-0.10.10.2-0.60.7-0.60.2-0.4-0.40.60.4-0.70.30.40.90.30.9-0.60.60.5
Short access day 10 total inactive lever presses0.32.18.6-1.41.40.8-1.4-0.7-1.71.7-0.91.50.6-0.3-0.60.9-1.7-1.8-0.7-1.7-1.71.82.9-1.4
Short access day 1 total infusions1.02.05.71.9-1.9-2.41.91.81.5-1.31.9-0.72.31.2-2.30.20.80.80.20.60.6-0.00.1-0.6
Short access day 10 total infusions0.50.83.50.8-0.8-0.80.80.90.8-0.81.2-0.70.61.9-0.4-1.00.70.61.40.60.5-0.41.10.3
Short access total infusions0.60.91.71.1-1.1-1.31.21.11.2-1.11.3-0.71.01.3-0.9-0.50.90.70.80.60.7-0.50.40.1
Short access day 1 locomotion1.62.65.42.2-2.2-2.32.22.01.9-1.72.2-1.41.71.9-1.6-0.91.31.41.01.21.1-0.7-0.10.2
Short access day 10 total locomotion0.51.96.31.3-1.4-1.61.32.10.9-1.01.9-1.11.32.5-0.9-1.61.10.81.60.80.2-0.42.00.1
Short access total locomotion2.03.07.72.0-2.0-2.22.02.41.6-1.52.4-1.51.82.8-1.4-1.81.41.21.71.20.7-0.51.40.2
One hour access (0.3 mA shock)0.60.71.20.9-0.8-0.60.90.61.0-1.10.7-0.90.00.90.1-0.61.10.90.90.90.8-0.9-0.70.7
Compulsive drug intake0.81.23.5-0.10.2-0.7-0.20.8-0.70.80.11.01.9-0.3-1.81.3-0.7-1.1-1.2-1.2-1.41.51.5-1.7
One hour access (shock baseline)0.51.42.60.9-0.9-0.20.90.21.3-1.30.5-1.4-1.00.71.1-1.31.41.51.31.51.5-1.6-1.41.5
Social response proportion0.81.04.70.9-0.70.00.70.10.8-0.80.3-1.2-0.90.21.0-1.10.81.11.01.01.1-1.1-2.21.2
Social responses0.30.41.40.2-0.00.40.00.4-0.10.10.1-0.5-1.00.41.0-1.20.50.40.90.50.0-0.4-1.10.7
Social time0.50.91.8-0.80.70.2-0.50.1-1.00.8-0.51.10.7-0.7-0.91.1-0.7-1.1-1.3-1.0-1.31.11.2-1.2
Soleus weight0.10.31.10.3-0.30.10.30.30.3-0.40.2-0.5-0.70.30.7-0.40.70.60.60.60.4-0.7-1.00.7
Bone: stiffness0.50.93.5-0.40.31.1-0.5-1.50.3-0.3-0.4-0.5-1.70.11.9-0.80.10.51.00.61.2-0.9-0.91.3
Tibialis anterior weight0.10.20.80.9-0.5-0.60.20.50.4-0.10.20.20.8-0.4-0.60.60.1-0.0-0.1-0.3-0.20.2-0.8-0.7
Time to tail flick, vehicle, before self-admin0.20.31.0-0.70.50.7-0.4-0.6-0.40.3-0.70.3-0.6-1.00.30.6-0.40.1-0.9-0.20.00.2-0.20.1
Time to tail flick, vehicle, after self-admin0.40.83.0-0.50.71.3-0.6-1.1-0.60.6-1.3-0.0-1.5-1.51.40.0-0.10.1-0.60.20.1-0.5-1.70.8
Time to tail flick, test, before self-admin1.82.04.41.7-1.7-1.21.50.72.1-2.01.2-1.5-0.10.90.1-1.01.71.81.21.51.9-1.7-1.01.1
Time to tail flick, test, after self-admin0.10.10.4-0.30.30.4-0.4-0.5-0.10.1-0.50.3-0.4-0.70.30.20.00.0-0.2-0.20.2-0.1-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.10.40.5-0.3-0.7-0.20.3-0.70.1-0.4-0.90.40.0-0.1-0.3-0.3-0.2-0.1-0.2-0.70.0
Delta time to tail flick, test, before/after SA0.30.40.9-0.50.50.1-0.60.1-0.70.6-0.40.80.5-0.5-0.50.7-0.4-0.7-0.7-0.7-0.90.70.3-0.9
Tibia length0.10.30.8-0.40.3-0.10.0-0.7-0.10.2-0.20.70.6-0.4-0.50.9-0.9-0.5-0.7-0.70.00.60.5-0.8
Ambulatory time before self-admin0.41.32.41.2-1.5-1.31.41.11.5-1.51.4-1.10.50.8-0.7-1.11.21.30.21.01.2-0.9-1.10.5
Ambulatory time after self-admin0.10.10.4-0.1-0.3-0.50.20.30.5-0.70.4-0.10.20.5-0.3-0.20.60.1-0.00.30.3-0.50.50.0
Bone: tissue strength0.40.41.51.2-0.8-1.00.70.50.9-0.50.5-0.31.20.0-0.8-0.40.10.20.3-0.00.20.20.0-0.5
Total heroin consumption0.30.31.60.3-0.20.10.10.30.2-0.20.5-0.5-0.61.00.7-0.60.60.41.30.40.3-0.60.40.6
Bone: trabecular number2.95.512.2-3.32.51.3-1.9-1.2-3.02.6-1.92.90.4-1.9-1.13.5-2.4-2.5-3.1-2.3-2.52.32.2-2.0
Bone: trabecular spacing2.23.36.32.5-2.0-1.21.51.12.4-2.11.5-2.2-0.11.50.6-2.52.02.02.41.92.0-1.8-0.81.5
Bone: trabecular thickness0.30.41.9-1.40.90.8-0.7-0.7-1.00.7-0.40.7-0.60.10.41.1-0.6-0.5-0.3-0.4-0.30.30.5-0.0
Bone: trabecular tissue density2.44.37.21.8-1.9-1.11.70.82.4-2.51.7-2.5-0.91.61.1-2.52.32.52.02.52.7-2.5-2.32.3
Water consumed over 24 hours0.20.41.4-1.20.80.9-0.7-0.4-0.90.6-0.40.3-1.00.40.80.1-0.2-0.30.4-0.0-0.3-0.00.80.4
Number of responses in last shaping day0.91.25.60.9-0.8-1.60.91.30.3-0.10.70.52.3-0.4-2.41.1-0.2-0.2-1.3-0.5-0.60.80.0-1.4