Mri1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Mri1 0.13 0.05 3.6e-13 0.1 0.11 0.11 0.11 1.8e-11 1.7e-12 7.6e-12 7.7e-12
2 NAcc gene expression Mri1 0.22 0.07 0.0e+00 0.14 0.18 0.17 0.19 4.2e-16 7.6e-21 6.5e-19 2.3e-21
3 BLA gene expression Mri1 0.29 0.1 2.0e-12 0.21 0.22 0.24 0.24 1.4e-11 1.0e-11 6.7e-13 4.7e-13
4 Liver gene expression Mri1 0.1 0.05 4.3e-08 0.05 0.05 0.05 0.05 5.8e-06 2.7e-06 2.6e-06 2.3e-06
5 OFC gene expression Mri1 0.27 0.12 5.4e-04 0.07 0.03 0.02 0.03 8.4e-03 8.4e-02 1.3e-01 8.6e-02
6 IL gene expression Mri1 0.26 0.11 3.7e-04 0.15 0.09 0.08 0.11 2.2e-04 3.5e-03 6.6e-03 1.2e-03
7 pVTA gene expression Mri1 0.15 0.08 9.5e-05 0.09 0.09 0.06 0.09 1.4e-04 1.0e-04 1.3e-03 1.4e-04
8 Brain gene expression Mri1 0.49 0.1 0.0e+00 0.47 0.5 0.52 0.52 2.7e-49 3.9e-53 5.9e-56 9.3e-56
9 Adipose mRNA stability Mri1 0.06 0.03 5.0e-07 0.05 0.05 0.04 0.05 1.9e-06 7.6e-06 1.1e-05 1.8e-06
10 OFC mRNA stability Mri1 0.6 0.42 1.2e-03 0.12 0.06 0.1 0.15 9.8e-04 1.7e-02 2.8e-03 2.1e-04
11 Brain mRNA stability Mri1 0.37 0.12 0.0e+00 0.38 0.39 0.41 0.41 4.2e-37 2.1e-38 2.1e-40 2.5e-40
12 Eye mRNA stability Mri1 0.55 0.21 1.2e-05 0.29 0.17 0.23 0.3 2.1e-05 1.5e-03 2.0e-04 1.8e-05
13 LHb mRNA stability Mri1 0.2 0.12 4.7e-03 0.09 0.01 0.01 0.03 4.6e-03 1.7e-01 1.8e-01 6.6e-02
14 pVTA mRNA stability Mri1 0.07 0.05 5.4e-03 0.03 0.03 0.01 0.01 1.3e-02 2.1e-02 9.3e-02 8.4e-02
15 NAcc mRNA stability Mri1 0.11 0.05 1.1e-16 0.15 0.15 0.15 0.15 2.5e-17 2.9e-17 5.8e-17 1.6e-17
16 BLA mRNA stability Mri1 0.17 0.07 5.2e-10 0.2 0.18 0.16 0.19 5.6e-11 9.3e-10 7.0e-09 1.3e-10
17 Liver mRNA stability Mri1 0.32 0.11 0.0e+00 0.24 0.23 0.23 0.24 6.2e-27 3.8e-25 1.5e-25 1.2e-26
18 PL mRNA stability Mri1 0.14 0.06 0.0e+00 0.16 0.15 0.16 0.13 8.6e-18 2.5e-16 1.0e-16 4.7e-14
19 Adipose gene expression Mri1 0.36 0.11 0.0e+00 0.29 0.32 0.32 0.32 2.9e-32 4.8e-36 1.1e-36 1.7e-36

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.52.66.62.62.02.40.5-1.9-2.00.5-2.5-1.6-1.41.7-1.21.31.2-1.21.31.31.20.5
Area under the delay curve0.10.20.6-0.3-0.3-0.4-0.80.30.4-0.6-0.1-0.6-0.5-0.0-0.60.20.3-0.30.10.10.20.4
BMI with tail1.55.017.5-2.5-1.8-2.40.11.82.10.22.43.64.2-2.52.5-1.8-1.92.1-1.7-1.7-2.0-1.7
BMI without tail0.20.32.2-0.9-0.6-0.7-0.50.40.6-0.50.50.91.5-0.40.1-0.0-0.10.20.00.1-0.20.0
Body weight0.10.52.6-0.50.2-0.21.0-0.20.10.80.61.61.3-0.40.7-0.5-0.40.4-0.4-0.4-0.4-0.5
Weight adjusted by age0.50.61.4-0.3-0.9-1.0-0.20.81.0-0.10.9-0.3-0.4-1.01.2-0.5-1.00.9-0.6-0.6-0.6-0.6
Bone surface2.54.46.91.81.62.2-0.7-2.0-2.0-0.9-2.5-2.4-1.52.6-2.32.42.4-2.42.42.42.41.9
Bone volume2.44.06.42.11.82.3-0.4-2.0-2.1-0.5-2.5-2.2-1.42.5-2.22.22.2-2.12.22.22.11.6
Breakpoint value in progressive ratio session4.24.69.30.30.5-0.33.00.20.22.91.33.01.7-1.72.7-2.5-2.32.3-2.6-2.6-2.5-2.8
Number of licking bursts0.30.31.00.70.80.80.8-0.7-1.00.7-0.80.60.20.2-0.20.20.2-0.20.20.20.3-0.1
Context. condit. distance diff. score0.60.71.9-1.4-0.8-1.3-0.01.10.8-0.11.21.20.4-0.90.1-0.8-0.60.6-0.8-0.8-0.8-0.2
Locomotion velocity, session 11.01.02.31.21.31.40.4-1.4-1.50.3-1.4-0.2-0.11.3-0.40.91.1-1.10.90.90.90.5
Locomotion distance, session 10.40.51.60.81.10.91.3-1.0-1.01.1-0.70.80.40.30.30.10.2-0.30.10.10.0-0.2
Locomotion velocity, session 20.40.51.21.01.01.00.5-1.1-1.10.5-1.0-0.3-0.70.6-0.50.50.5-0.60.50.50.40.2
Locomotion distance, session 20.40.62.60.30.70.31.5-0.6-0.71.40.01.60.9-0.30.9-0.5-0.50.4-0.5-0.5-0.6-0.7
Locomotion velocity, session 30.10.20.6-0.5-0.5-0.2-0.80.20.3-0.70.1-0.20.40.2-0.50.40.3-0.30.40.40.30.5
Locomotion distance, session 32.02.23.90.10.40.6-1.3-0.9-0.8-1.5-1.2-1.6-0.91.4-1.82.01.8-1.82.02.01.82.0
Stereotopy head waving bouts, day 31.11.35.1-1.5-1.5-1.0-2.30.91.2-2.20.4-0.70.60.2-0.80.80.7-0.70.80.80.81.2
Stereotopy head waving duration, day 30.40.51.7-1.1-1.2-0.9-1.30.91.1-1.10.60.00.7-0.4-0.10.0-0.00.00.00.00.10.4
Locomotion velocity, session 70.10.10.5-0.7-0.3-0.4-0.40.10.1-0.50.20.50.6-0.1-0.30.30.4-0.30.30.30.20.5
Locomotion distance, session 70.20.20.70.40.60.40.8-0.7-0.60.8-0.30.60.40.00.20.0-0.00.10.00.0-0.1-0.3
Stereotopy head waving bouts, day 72.02.26.00.0-0.00.5-1.7-0.4-0.3-1.8-1.1-2.1-1.31.3-2.51.61.8-1.71.61.61.72.0
Stereotopy head waving duration, day 71.51.94.60.30.20.7-1.3-0.6-0.7-1.5-1.3-1.8-1.11.4-2.11.51.6-1.61.51.51.71.7
Locomotion velocity, session 80.20.20.80.10.60.30.8-0.7-0.80.7-0.00.90.20.30.00.10.0-0.10.10.1-0.1-0.1
Locomotion distance, session 80.30.52.8-0.30.3-0.21.2-0.1-0.51.00.41.70.6-0.50.5-0.6-0.50.4-0.6-0.6-0.7-0.5
Degree of sensitization distance1.71.73.40.30.2-0.21.80.10.21.90.81.80.9-1.11.7-1.5-1.51.5-1.5-1.5-1.6-1.8
Degree of sensitization stereotypy0.91.02.8-0.3-0.30.1-1.2-0.10.0-1.4-0.6-1.3-0.50.8-1.71.01.2-1.11.01.01.11.4
Conditioned locomotion0.10.10.20.30.50.40.4-0.4-0.40.3-0.20.0-0.20.2-0.20.20.1-0.10.20.20.00.0
Cocaine response after cond. corrected1.01.13.3-0.3-0.0-0.51.10.40.11.21.01.80.9-1.01.4-1.1-1.21.2-1.2-1.2-1.2-1.2
Cocaine response after cond. not corrected1.41.64.3-0.10.2-0.41.50.3-0.01.60.92.10.9-1.21.6-1.4-1.41.4-1.4-1.4-1.5-1.6
Cocaine response before conditioning0.20.30.60.70.60.70.0-0.6-0.70.1-0.8-0.5-0.50.6-0.50.50.5-0.50.50.50.50.3
Saline control response1.62.28.12.22.41.92.9-2.1-1.82.6-1.30.6-0.70.30.5-0.1-0.20.2-0.1-0.1-0.2-1.0
Bone: connectivity density3.14.910.42.82.32.9-0.0-2.4-2.5-0.1-3.2-2.4-2.12.5-1.92.12.2-2.22.12.12.11.4
Bone: cortical apparent density0.20.31.0-0.9-0.8-0.7-1.00.70.9-1.00.30.00.3-0.50.10.10.10.10.10.10.20.3
Bone: cortical area0.20.30.90.40.80.60.6-0.9-0.60.3-0.50.0-0.20.5-1.00.60.6-0.50.60.60.50.4
Bone: cortical porosity0.50.51.4-0.6-0.7-0.80.20.70.80.31.2-0.0-0.4-0.90.4-0.8-0.80.9-0.8-0.8-0.9-0.5
Bone: cortical porosity0.10.10.7-0.6-0.4-0.5-0.10.40.5-0.20.8-0.4-0.6-0.3-0.2-0.1-0.10.2-0.1-0.1-0.20.2
Bone: cortical thickness0.50.82.0-1.3-0.7-1.10.40.80.90.21.31.41.1-1.20.5-0.8-0.80.9-0.8-0.8-0.9-0.5
Bone: cortical thickness3.64.28.50.70.4-0.22.70.30.22.90.72.41.4-2.32.2-2.5-2.52.5-2.5-2.5-2.4-2.9
Bone: cortical tissue density0.20.31.2-0.8-0.7-0.6-1.10.60.8-1.10.1-0.10.3-0.3-0.10.30.3-0.10.30.30.40.5
Condit. Reinf. active minus inactive responses1.51.74.6-1.7-0.8-0.8-1.80.20.8-2.10.2-1.0-0.60.3-1.71.41.4-1.31.41.41.32.1
Condit. Reinf. active-inactive response ratio0.30.41.8-1.3-0.5-1.0-0.50.41.0-0.70.80.0-0.4-0.7-0.50.20.10.00.20.20.10.6
Condit. Reinf. active responses1.41.74.0-0.9-0.4-0.3-1.7-0.20.2-1.9-0.4-1.4-1.00.7-1.61.51.5-1.51.61.61.52.0
Condit. Reinf. inactive responses1.92.33.71.41.21.6-0.4-1.5-1.7-0.4-1.9-1.8-1.51.9-1.21.61.7-1.81.61.61.61.3
Incentive salience index mean2.73.26.9-0.60.00.3-1.9-0.7-0.1-2.3-1.0-1.9-1.11.4-2.32.32.3-2.22.32.32.32.6
Condit. Reinf. lever presses3.14.26.60.50.71.3-1.6-1.3-1.1-1.9-1.8-2.4-1.62.2-2.32.52.6-2.62.62.62.52.5
Condit. Reinf. active minus inactive responses0.40.51.1-0.00.30.4-0.4-0.6-0.3-0.6-0.5-0.40.20.9-1.01.00.9-1.00.90.91.01.0
Condit. Reinf. active-inactive response ratio0.00.10.2-0.3-0.3-0.3-0.10.30.3-0.10.40.10.3-0.10.0-0.2-0.20.1-0.2-0.2-0.1-0.0
Condit. Reinf. active responses0.10.20.50.20.40.50.3-0.7-0.20.1-0.40.20.70.4-0.40.40.3-0.50.30.30.40.2
Condit. Reinf. inactive responses0.40.51.50.10.1-0.00.9-0.10.40.90.31.01.2-0.60.7-0.7-0.80.7-0.7-0.7-0.8-0.9
Condit. Reinf. lever presses0.10.20.8-0.3-0.4-0.30.00.40.40.10.30.70.9-0.30.1-0.5-0.40.3-0.5-0.5-0.4-0.4
Condit. Reinf. lever reinforcers received0.10.10.30.20.20.30.2-0.4-0.00.1-0.20.10.60.3-0.40.20.2-0.40.20.20.20.1
Conditioned reinforcement - actives0.00.00.1-0.2-0.2-0.20.10.20.10.00.30.0-0.1-0.10.0-0.3-0.10.2-0.3-0.3-0.1-0.1
Conditioned reinforcement - inactives0.10.10.4-0.4-0.4-0.2-0.50.4-0.1-0.60.2-0.20.00.3-0.6-0.10.4-0.3-0.1-0.10.40.4
Conditioned locomotion0.10.11.2-0.5-0.4-0.3-0.50.20.1-0.40.10.51.10.1-0.00.10.2-0.30.10.10.20.2
Patch foraging indifference point 0 sec0.40.61.6-0.40.40.1-0.4-0.5-0.4-0.9-0.3-0.6-0.10.8-1.01.20.9-0.91.21.20.91.2
Patch foraging indifference point AUC0.81.03.21.71.41.51.3-1.3-1.81.3-1.1-0.1-0.70.90.0-0.10.4-0.40.00.00.1-0.4
Delay disc. indifference point, 0s delay0.50.51.20.80.80.9-0.3-1.0-0.7-0.1-1.1-0.3-0.10.9-0.80.80.7-0.70.70.70.80.4
Delay disc. indifference point, 16s delay1.01.02.0-0.6-0.6-1.10.31.10.80.61.01.00.6-1.20.8-1.4-1.11.1-1.4-1.4-1.1-1.0
Delay disc. indifference point, 2s delay0.50.51.6-0.8-1.1-1.1-1.01.01.2-0.80.8-0.8-0.4-0.7-0.3-0.1-0.40.4-0.1-0.1-0.40.1
Delay disc. indifference point, 24s delay0.30.31.0-1.0-0.6-0.8-0.70.70.4-0.70.5-0.3-0.3-0.0-0.7-0.00.3-0.40.00.00.20.7
Delay disc. indifference point, 4s delay0.80.82.60.70.30.6-0.9-0.4-0.3-0.8-1.0-1.6-1.10.8-1.11.00.9-0.81.01.00.80.8
Delay disc. indifference point, 8s delay0.20.20.9-0.6-0.6-0.7-1.00.20.6-0.80.0-0.4-0.0-0.0-0.50.30.4-0.40.20.20.30.6
Indifference point function ln k1.11.65.0-2.2-1.8-1.6-2.11.41.8-2.21.0-0.11.0-0.5-0.60.50.2-0.20.50.50.41.1
Indifference point function log k1.11.65.0-2.2-1.8-1.6-2.11.41.8-2.21.0-0.11.0-0.5-0.60.50.2-0.20.50.50.41.1
Patch foraging total patch changes 0 sec0.20.30.7-0.70.0-0.3-0.4-0.1-0.0-0.80.2-0.20.30.4-0.60.80.5-0.50.80.80.50.9
Patch foraging total patch changes 12 sec1.31.74.71.21.81.61.1-1.8-2.20.6-1.5-0.4-0.91.5-1.11.01.3-1.31.11.11.10.9
Patch foraging total patch changes 18 sec2.12.76.32.22.42.41.5-2.5-2.41.1-2.1-0.7-0.91.8-1.11.11.3-1.41.11.11.20.6
Patch foraging total patch changes 24 sec1.51.93.61.31.71.50.6-1.8-1.90.1-1.5-0.9-1.01.6-1.21.31.5-1.41.51.51.31.0
Patch foraging total patch changes 6 sec0.30.51.51.11.11.00.8-1.0-1.20.7-0.8-0.3-0.40.7-0.30.20.4-0.40.30.30.20.0
Patch foraging time to switch 0 sec0.10.10.50.60.60.40.7-0.4-0.20.7-0.3-0.2-0.6-0.0-0.2-0.1-0.10.2-0.2-0.2-0.1-0.2
Patch foraging water rate 0 sec0.10.20.9-0.2-0.1-0.10.3-0.00.40.20.40.70.9-0.30.5-0.2-0.40.4-0.2-0.2-0.4-0.5
Patch foraging water rate 12 sec0.50.83.4-1.1-1.3-0.8-1.80.71.3-1.60.3-0.41.0-0.2-0.30.40.3-0.40.40.40.40.7
Patch foraging water rate 18 sec1.92.56.0-0.6-0.70.0-2.40.10.2-2.5-0.7-1.9-0.31.2-1.71.91.9-1.81.81.82.02.1
Patch foraging water rate 24 sec0.81.13.8-1.1-0.9-0.5-1.90.50.4-1.9-0.0-0.70.20.5-1.21.21.0-1.01.11.11.11.4
Patch foraging water rate 6 sec1.52.25.52.22.12.31.0-2.3-1.80.9-2.1-0.6-0.51.6-0.81.21.2-1.21.21.21.30.4
Seeking ratio, delayed vs. immediate footshock1.31.43.2-1.3-1.6-1.4-0.71.41.8-0.31.20.91.3-1.61.4-0.8-1.21.1-0.9-0.9-1.2-0.7
Distance traveled before self-admin0.40.40.9-0.4-0.7-0.80.00.80.70.00.9-0.3-0.6-0.70.6-0.8-0.70.7-0.7-0.7-0.8-0.5
Distance traveled after self-admin0.30.31.0-0.6-1.0-0.7-0.41.00.6-0.40.9-0.10.0-0.4-0.1-0.7-0.30.4-0.7-0.7-0.4-0.3
Extensor digitorum longus weight0.20.91.9-0.30.1-0.51.40.20.31.11.01.20.7-0.91.1-1.1-1.01.1-1.0-1.0-1.1-1.1
Bone: elastic displacement0.50.52.0-1.4-0.9-0.8-1.10.60.3-1.20.60.51.2-0.0-0.30.30.4-0.40.30.30.40.7
Bone: elastic work1.01.24.8-1.7-1.2-1.4-0.41.21.0-0.41.41.62.2-1.00.8-0.7-0.60.7-0.7-0.7-0.7-0.4
Bone: endosteal estimation0.30.82.61.31.51.31.6-1.3-1.01.4-0.80.60.10.5-0.00.10.1-0.10.10.10.1-0.4
Bone: endosteal perimeter1.32.64.51.41.91.80.7-2.1-1.80.2-1.6-1.1-1.31.9-2.11.71.7-1.81.71.71.71.4
Epididymis fat weight0.30.62.80.61.00.41.7-0.5-0.31.50.11.10.2-0.20.4-0.7-0.60.5-0.6-0.6-0.6-0.9
Delta time in closed arm before/after self-admin0.60.61.5-1.1-1.1-1.2-0.90.91.2-0.70.9-0.3-0.1-0.90.8-0.2-0.40.5-0.2-0.2-0.50.1
Delta time in open arm before/after self-admin2.32.27.72.02.51.82.8-2.1-2.02.5-1.31.30.10.7-0.3-0.2-0.10.1-0.2-0.2-0.1-1.0
Diff in mean of infusions in LGA sessions0.20.20.90.60.60.51.0-0.6-0.50.9-0.30.50.2-0.00.2-0.2-0.30.2-0.2-0.2-0.3-0.5
Delay discount exponential model param0.20.20.80.30.40.40.9-0.4-0.40.70.10.80.6-0.10.8-0.3-0.40.4-0.2-0.2-0.3-0.6
Extinction: sum of active levers before priming1.41.44.3-1.8-1.6-1.6-1.31.41.8-1.01.21.12.1-1.20.6-0.3-0.60.7-0.2-0.2-0.8-0.2
Active lever presses in extinction session 61.11.12.6-0.8-0.7-0.0-1.60.30.1-1.6-0.3-0.8-0.11.0-1.30.91.5-1.40.80.81.31.5
Bone: final force0.20.31.60.60.70.51.3-0.5-0.41.1-0.00.70.20.00.4-0.4-0.20.3-0.4-0.4-0.3-0.6
Bone: final moment0.20.31.40.40.60.41.2-0.4-0.31.00.10.80.4-0.10.4-0.3-0.20.3-0.3-0.3-0.3-0.5
Food consumed during 24 hour testing period3.64.412.83.63.53.12.9-3.1-3.02.7-2.6-0.1-1.51.5-0.30.70.6-0.70.70.70.6-0.6
Glucose0.00.00.1-0.2-0.1-0.00.0-0.0-0.1-0.10.30.10.10.30.30.10.1-0.10.10.20.10.1
Heart weight0.60.82.3-1.4-1.5-1.4-1.51.21.5-1.30.6-0.00.8-1.00.3-0.1-0.00.2-0.1-0.1-0.20.3
Delay discount hyperbolic model param0.30.31.00.30.40.41.0-0.3-0.40.70.21.00.8-0.10.9-0.3-0.40.4-0.3-0.3-0.4-0.7
Intermittent access intake day 1-15 change1.81.73.21.51.51.70.4-1.5-1.80.2-1.6-0.9-1.21.7-1.41.01.5-1.51.01.01.51.0
Intermittent access intake escalation2.02.04.21.71.81.90.7-1.6-2.00.4-1.7-0.8-1.21.7-1.31.11.5-1.41.11.11.40.9
Intermittent access intake escalation 22.32.23.81.41.61.90.1-1.6-2.0-0.1-1.8-0.9-1.01.9-1.51.51.7-1.71.51.51.71.2
Intermitt. access day 1 inactive lever presses0.90.92.5-0.5-0.30.2-1.5-0.1-0.0-1.6-0.6-0.60.40.9-0.91.21.2-1.11.21.21.21.2
Intermitt. access day 15 inactive lever presses0.40.41.1-0.6-0.4-0.60.20.60.30.20.81.01.1-0.50.7-0.6-0.50.6-0.7-0.7-0.5-0.6
Intermitt. access escalation Index0.20.10.30.40.50.50.4-0.6-0.60.4-0.50.40.40.4-0.10.20.2-0.30.20.20.1-0.0
Intermittent access day 1 total infusions1.01.22.4-1.3-1.3-1.4-0.41.31.3-0.31.31.21.5-1.10.9-1.0-1.01.0-0.9-0.9-1.0-0.7
Intermittent access day 15 total infusions0.00.00.1-0.10.00.1-0.20.0-0.2-0.3-0.1-0.00.00.3-0.4-0.00.3-0.30.10.10.30.2
Intermittent access terminal intake (last 3 days)0.10.10.3-0.4-0.3-0.2-0.40.2-0.0-0.50.10.20.30.3-0.3-0.00.3-0.20.00.00.30.3
Intermittent access total infusions0.10.20.5-0.6-0.5-0.5-0.20.50.3-0.30.50.60.7-0.10.1-0.4-0.10.1-0.3-0.3-0.1-0.1
Intermittent access day 1 locomotion0.90.96.1-1.3-1.1-1.1-0.80.91.0-0.70.81.62.5-0.60.7-0.4-0.40.4-0.3-0.3-0.4-0.4
Intermittent access day 15 total locomotion1.31.43.6-0.7-0.5-0.90.80.90.50.81.21.91.8-1.01.2-1.4-1.21.1-1.3-1.3-1.2-1.3
Intermittent access total locomotion1.71.95.7-1.1-0.9-1.30.51.20.90.51.42.22.4-1.21.5-1.5-1.31.3-1.4-1.4-1.4-1.4
Intermittent access standard deviation1.51.63.2-0.2-0.20.3-1.6-0.1-0.6-1.6-0.8-1.4-0.71.3-1.71.31.7-1.61.21.21.71.8
Left kidney weight0.30.81.81.11.31.21.3-1.4-1.10.9-1.0-0.5-1.20.7-0.40.50.7-0.70.40.40.60.3
Right kidney weight0.20.52.50.71.20.71.6-1.0-1.01.2-0.50.2-0.70.2-0.20.10.2-0.2-0.00.00.10.0
Cocaine induced anxiety0.10.10.4-0.3-0.3-0.2-0.50.20.2-0.60.1-0.6-0.40.2-0.40.20.3-0.30.20.20.30.4
Post-drug Anxiety0.50.51.4-1.0-1.1-1.1-0.51.20.9-0.41.0-0.10.0-0.70.2-0.7-0.40.4-0.8-0.8-0.4-0.0
Baseline Anxiety1.01.02.00.20.1-0.31.30.30.31.40.70.90.0-1.11.2-1.3-1.31.2-1.3-1.3-1.3-1.3
Tail length2.16.310.82.42.32.70.0-2.6-2.5-0.3-2.7-2.9-3.33.0-3.12.42.6-2.72.42.42.62.2
Length with tail0.82.99.01.92.02.01.0-1.9-2.10.6-1.6-2.0-3.02.0-1.71.11.5-1.61.11.11.51.2
Length without tail0.51.02.2-0.10.0-0.41.50.40.01.41.01.10.1-0.81.3-1.5-1.11.1-1.4-1.4-1.1-1.2
Times rat made contact with spout0.00.00.00.2-0.00.0-0.0-0.0-0.20.1-0.20.10.2-0.10.1-0.0-0.10.1-0.0-0.0-0.1-0.2
Lifetime Intake0.10.10.3-0.5-0.4-0.4-0.20.40.3-0.40.40.40.5-0.0-0.0-0.3-0.00.1-0.3-0.3-0.1-0.0
Liver weight, left0.71.13.71.81.61.31.9-1.3-1.01.9-0.90.80.20.20.5-0.3-0.30.3-0.4-0.4-0.4-1.1
Liver weight, right0.50.93.31.31.61.31.8-1.3-1.21.6-0.80.8-0.10.40.60.0-0.10.0-0.0-0.0-0.1-0.6
Locomotor activity1.52.45.10.20.1-0.11.80.40.32.00.82.32.0-1.52.1-1.8-1.71.7-1.8-1.8-1.7-2.1
Locomotor testing distance1.72.85.70.40.20.01.90.40.42.10.72.22.0-1.62.3-1.8-2.02.0-1.8-1.8-1.9-2.4
Locomotor testing rearing0.91.44.91.91.81.72.2-1.4-1.12.1-1.10.6-0.00.00.4-0.4-0.30.4-0.3-0.3-0.2-1.0
Locomotion in novel chamber2.12.54.90.10.1-0.42.00.40.62.11.02.11.3-1.72.2-1.8-1.91.8-1.8-1.8-1.8-2.1
Locomotion in novel chamber post-restriction0.20.32.80.0-0.00.3-0.3-0.2-0.1-0.3-0.30.81.70.40.10.40.2-0.30.40.40.4-0.1
Fecal boli incidents, locomotor time 12.22.48.41.51.71.80.3-1.5-1.80.1-1.5-2.1-2.91.8-1.41.31.2-1.31.41.41.31.3
Change in fecal boli incidents, locomotor task0.80.71.30.20.00.5-1.1-0.3-0.2-1.1-1.0-0.80.10.7-0.81.11.0-1.01.11.11.00.9
Time >=10cm from walls, locomotor time 10.20.20.70.70.10.40.30.1-0.10.4-0.2-0.8-0.8-0.30.1-0.3-0.40.4-0.3-0.3-0.4-0.4
Bouts of movement, locomotor time 10.50.51.7-0.4-0.5-0.1-1.20.3-0.0-1.1-0.1-1.3-0.60.6-0.80.60.9-0.80.50.50.81.0
Total resting periods, locomotor time 10.80.92.8-0.8-0.8-0.4-1.70.70.2-1.60.1-1.4-0.40.6-0.90.71.0-0.90.60.60.91.3
Rest time, locomotor task time 10.70.82.6-1.0-0.9-0.6-1.60.80.3-1.60.3-1.1-0.40.4-0.50.60.9-0.90.60.60.91.3
Distance moved, locomotor task time 11.21.33.80.20.1-0.21.40.10.21.50.61.91.3-1.01.2-1.3-1.31.3-1.2-1.2-1.3-1.7
Vertical activity count, locomotor time 12.32.47.52.62.21.92.7-2.0-1.72.7-1.10.2-1.90.20.5-0.6-0.60.6-0.5-0.5-0.6-1.4
Time >=10cm from walls, locomotor time 20.91.01.6-0.7-1.0-1.1-0.11.21.00.21.20.60.7-1.10.7-1.2-1.11.1-1.2-1.2-1.1-1.0
Bouts of movement, locomotor time 20.40.41.1-0.8-1.1-0.9-0.81.10.9-0.60.6-0.10.5-0.60.7-0.4-0.20.3-0.4-0.4-0.3-0.1
Total resting periods, locomotor time 20.20.20.5-0.3-0.7-0.5-0.40.70.5-0.20.4-0.20.0-0.50.7-0.4-0.20.3-0.4-0.4-0.3-0.2
Rest time, locomotor task time 20.30.31.40.80.60.70.2-0.6-0.70.3-0.7-0.8-1.20.4-0.10.40.2-0.20.30.30.10.2
Distance moved, locomotor task time 22.02.34.3-1.6-1.6-1.8-0.01.61.50.21.91.92.1-1.51.1-1.6-1.31.3-1.7-1.7-1.3-1.2
Vertical activity count, locomotor time 20.60.72.60.91.00.91.6-0.9-0.81.6-0.20.8-0.50.00.3-0.8-0.30.3-0.8-0.8-0.2-0.8
Light reinforcement 17.112.931.05.35.55.33.6-5.6-4.63.0-4.5-1.6-3.53.4-2.22.52.1-2.22.42.42.30.6
Light reinforcement 26.08.019.34.34.44.23.2-4.2-3.82.6-3.3-1.3-3.02.8-1.81.71.6-1.51.51.51.60.2
Bone: marrow area0.30.72.71.31.41.21.7-1.2-0.91.4-0.80.60.10.40.10.00.1-0.10.00.00.0-0.5
Bone: maximum diameter0.61.13.20.10.60.6-0.4-0.9-0.4-0.7-0.6-0.8-0.81.1-1.81.31.4-1.31.31.31.21.4
Bone: maximum force0.10.10.60.20.50.30.8-0.4-0.20.60.10.60.40.10.1-0.10.00.1-0.1-0.1-0.1-0.2
Bone: maximum moment0.10.10.50.10.40.20.7-0.4-0.20.50.10.60.50.10.00.00.10.00.00.0-0.0-0.1
Mean time between licks in bursts0.10.20.4-0.4-0.0-0.1-0.4-0.1-0.4-0.5-0.30.10.10.2-0.30.50.5-0.50.50.50.60.6
Mean num. licks in bursts0.30.31.5-0.6-0.9-0.7-1.20.70.9-1.00.5-0.70.1-0.20.10.10.0-0.00.10.1-0.10.2
Cd content in liver0.60.61.5-0.30.20.1-0.6-0.3-0.5-0.8-0.5-0.8-1.10.6-0.81.11.0-0.91.01.00.91.2
Co content in liver1.41.65.7-2.2-1.8-1.5-2.41.21.2-2.40.9-0.60.4-0.2-0.50.70.6-0.50.70.70.71.4
Cu content in liver0.10.20.8-0.9-0.5-0.6-0.10.40.5-0.30.50.60.5-0.60.1-0.1-0.10.3-0.1-0.1-0.10.1
Fe content in liver0.70.93.0-0.3-0.6-0.1-1.70.20.2-1.5-0.1-1.4-0.60.9-0.91.01.0-0.91.01.01.01.2
K content in liver0.50.54.4-0.7-0.4-0.40.10.30.60.10.51.52.1-0.20.5-0.3-0.20.1-0.3-0.3-0.3-0.3
Mg content in liver0.60.75.2-1.3-0.9-0.6-0.80.61.0-0.80.61.22.3-0.10.30.10.2-0.10.10.10.10.3
Mn content in liver0.10.10.7-0.10.20.30.5-0.40.10.2-0.10.60.80.20.30.30.4-0.30.30.30.30.2
Na content in liver0.30.30.80.50.10.20.50.10.00.80.00.70.8-0.20.9-0.6-0.60.6-0.6-0.6-0.5-0.9
Rb content in liver0.10.20.3-0.10.20.2-0.4-0.2-0.3-0.4-0.2-0.10.10.5-0.30.60.6-0.50.60.60.60.5
Se content in liver1.82.24.00.50.51.0-1.0-1.1-0.7-1.1-1.1-1.7-1.12.0-1.91.81.8-2.01.81.81.81.9
Sr content in liver0.30.31.1-1.0-0.4-0.60.10.40.70.00.71.01.0-0.50.4-0.3-0.30.3-0.3-0.3-0.3-0.1
Zn content in liver0.30.30.7-0.5-0.2-0.50.60.40.40.30.60.50.4-0.80.2-0.7-0.60.7-0.7-0.7-0.6-0.4
Bone: minimum diameter1.02.05.01.92.12.01.4-2.0-2.21.1-1.6-0.5-1.11.4-1.01.01.0-0.91.01.00.90.3
Time in familiar zone, hab. session 10.70.72.00.60.60.6-0.2-0.8-0.7-0.3-1.0-1.1-1.40.6-1.10.80.8-0.80.80.80.80.8
Time in novel zone, hab. session 11.61.63.4-0.9-1.3-1.2-0.41.51.40.01.31.11.8-1.31.5-1.3-1.31.4-1.3-1.3-1.3-1.2
Total zone transitions, hab. session 10.30.51.71.10.80.71.2-0.6-0.81.3-0.40.5-0.00.00.6-0.4-0.50.3-0.4-0.4-0.5-0.8
Total locomotion distance, hab. session 10.30.41.10.60.40.40.8-0.3-0.41.0-0.21.00.8-0.21.0-0.5-0.50.4-0.5-0.5-0.5-0.8
Locomotion velocity, hab. session 10.30.51.40.80.80.71.1-0.7-0.81.2-0.41.00.70.11.0-0.3-0.40.2-0.3-0.3-0.3-0.7
Time in familiar zone, hab. session 21.11.12.21.21.31.30.5-1.5-1.20.3-1.4-0.7-1.11.1-0.71.11.0-1.01.11.11.10.7
Time in novel zone, hab. session 23.33.34.6-1.6-1.6-2.00.12.01.80.32.11.92.0-2.11.6-2.0-2.01.9-2.0-2.0-2.0-1.6
Total zone transitions, hab. session 20.60.82.41.11.21.30.8-1.4-1.50.7-1.20.30.20.8-0.10.70.6-0.70.70.70.60.2
Total locomotion distance, hab. session 20.40.51.50.81.00.91.2-1.1-1.11.1-0.60.90.70.30.70.10.0-0.10.10.10.0-0.4
Locomotion velocity, hab. session 20.40.61.60.91.11.01.3-1.1-1.21.2-0.60.80.40.40.70.10.0-0.10.10.10.0-0.4
Novel to familiar place preference ratio1.21.32.2-0.6-0.7-0.90.40.91.20.61.01.31.1-1.51.2-1.2-1.41.4-1.2-1.2-1.3-1.4
Novelty place preference1.61.72.8-0.4-0.6-0.80.60.91.20.91.01.51.2-1.61.5-1.5-1.71.7-1.5-1.5-1.5-1.7
Time in novel zone, NPP test1.92.03.1-0.7-1.0-1.20.21.31.50.51.21.51.5-1.81.6-1.6-1.71.8-1.6-1.6-1.6-1.6
Total zone transitions, NPP test0.81.22.91.21.71.51.3-1.7-1.70.9-1.20.1-0.61.2-0.50.80.9-1.00.80.80.80.5
Total locomotion distance, NPP test0.20.20.50.40.70.60.6-0.7-0.70.5-0.50.60.50.30.30.20.3-0.30.20.20.20.0
Locomotion velocity, NPP test0.30.51.30.61.10.91.0-1.1-1.10.8-0.60.60.00.60.00.40.5-0.60.40.40.40.2
Intraocular pressure1.52.15.7-2.4-2.3-2.2-1.52.31.6-1.31.90.51.1-1.40.7-1.1-0.80.7-1.1-1.0-0.80.0
Delta distance traveled before/after self-admin0.10.10.7-0.3-0.4-0.0-0.40.10.2-0.30.00.40.8-0.0-0.10.10.1-0.10.00.00.10.1
Delta ambulatory time before/after self-admin0.40.50.90.20.20.7-0.6-0.4-0.6-0.5-0.8-0.20.20.8-0.80.81.0-1.00.70.71.00.8
Parametrial fat weight0.10.30.70.70.80.70.8-0.7-0.80.6-0.4-0.2-0.50.6-0.50.10.2-0.30.10.00.2-0.0
Pavlov. Cond. lever latency0.50.72.00.70.60.31.4-0.2-0.11.4-0.10.90.2-0.60.9-0.9-0.80.7-0.9-0.9-0.9-1.1
Pavlov. Cond. magazine entry latency0.60.72.1-1.3-1.4-1.1-1.41.21.1-1.20.9-0.10.8-0.60.4-0.1-0.30.4-0.1-0.1-0.10.1
Pavlov. Cond. change in total contacts1.21.32.3-0.10.10.5-1.2-0.5-0.4-1.4-0.7-1.4-0.51.2-1.41.51.4-1.31.51.51.51.5
Pavlov. Cond. index score0.60.72.9-1.2-1.1-0.7-1.70.70.5-1.70.5-0.50.40.2-0.50.70.5-0.50.70.70.70.9
Pavlov. Cond. latency score0.40.51.7-0.9-0.7-0.4-1.30.40.2-1.30.3-0.50.10.4-0.50.70.6-0.50.70.70.70.9
Pavlov. Cond. lever contacts0.40.41.7-0.8-0.8-0.4-1.30.40.4-1.30.3-0.60.20.3-0.50.60.4-0.40.60.60.60.7
Pavlov. Cond. magazine entry number1.01.24.71.71.71.22.2-1.4-1.42.0-0.90.5-0.80.20.1-0.4-0.30.2-0.4-0.4-0.4-0.8
Pavlov. Cond. intertrial magazine entries1.31.63.5-0.30.20.4-0.7-0.9-0.4-1.2-0.6-1.3-1.01.4-1.91.51.6-1.71.61.61.51.9
Pavlov. Cond. lever-magazine prob. diff.0.70.83.0-1.5-1.4-1.1-1.71.10.8-1.70.9-0.30.7-0.0-0.30.40.2-0.20.40.40.40.7
Pavlov. Cond. response bias0.81.04.0-1.4-1.6-1.1-2.01.21.4-1.80.8-0.50.8-0.2-0.10.30.1-0.10.30.30.30.6
Pavlov. Cond. lever latency0.10.10.5-0.20.0-0.30.30.1-0.20.20.4-0.1-0.7-0.20.2-0.2-0.30.3-0.2-0.2-0.2-0.1
Pavlov. Cond. magazine entry latency0.10.10.90.10.20.10.1-0.1-0.3-0.0-0.2-0.1-0.40.3-0.90.20.3-0.50.20.20.10.4
Pavlov. Cond. change in total contacts0.30.40.9-0.2-0.40.1-0.90.00.2-0.9-0.4-0.60.30.5-0.80.70.7-0.80.60.60.60.8
Pavlov. Cond. index score0.10.20.60.1-0.10.2-0.50.00.1-0.5-0.4-0.30.20.4-0.80.40.4-0.60.40.40.30.5
Pavlov. Cond. latency score0.10.20.80.1-0.10.2-0.5-0.00.0-0.5-0.4-0.30.20.5-0.90.40.5-0.60.40.40.40.5
Pavlov. Cond. lever contacts0.00.00.20.40.20.40.1-0.2-0.10.2-0.40.10.30.1-0.10.00.1-0.10.00.0-0.0-0.1
Pavlov. Cond. magazine entry number0.10.10.90.20.1-0.00.3-0.0-0.10.50.10.3-0.1-0.40.9-0.3-0.40.5-0.3-0.3-0.3-0.6
Pavlov. Cond. intertrial magazine entries1.21.63.51.71.81.71.1-1.9-1.60.8-1.6-0.9-1.21.2-0.61.00.9-0.91.01.01.10.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.1-0.20.1-0.50.10.2-0.5-0.2-0.10.40.3-0.60.30.4-0.50.30.30.20.4
Pavlov. Cond. response bias0.00.00.20.1-0.10.1-0.00.10.20.0-0.10.20.50.1-0.1-0.10.0-0.1-0.1-0.1-0.1-0.0
Time in closed arm before self-admin0.80.91.40.50.10.9-0.9-0.3-0.4-1.0-0.9-1.1-0.51.0-1.11.11.1-1.11.21.21.21.0
Time in closed arm after self-admin0.40.42.7-0.1-0.5-0.2-0.70.40.5-0.60.2-1.5-1.6-0.20.20.3-0.10.10.40.4-0.00.4
Time in open arm before self-admin0.60.61.6-1.2-1.3-1.2-1.01.21.2-0.81.0-0.2-0.0-0.80.3-0.6-0.30.4-0.6-0.6-0.40.1
Time in open arm after self-admin0.60.72.9-0.30.1-0.50.90.20.20.90.51.71.5-0.60.4-0.9-0.80.8-1.0-1.0-0.8-0.9
Bone: periosteal estimation0.51.13.11.51.81.51.6-1.6-1.31.3-1.10.2-0.50.8-0.70.50.6-0.50.50.50.50.0
Bone: periosteal perimeter1.22.04.50.91.61.40.6-1.8-1.50.0-1.3-0.8-1.11.5-2.11.61.6-1.61.61.61.51.4
Bone: post-yield work0.40.52.01.41.11.11.1-0.9-0.51.1-0.8-0.4-0.80.30.0-0.1-0.00.2-0.1-0.1-0.0-0.6
Progressive ratio test 1 active lever presses1.41.52.3-1.4-1.3-1.5-0.21.41.5-0.21.51.21.4-1.31.2-1.2-1.21.2-1.1-1.1-1.2-0.9
Progressive ratio test 1 breakpoint1.11.11.9-1.3-1.2-1.4-0.31.31.3-0.31.31.01.2-1.10.9-1.0-1.01.0-1.0-1.0-1.0-0.7
Progressive ratio test 1 inactive lever presses0.10.10.5-0.7-0.5-0.4-0.50.40.3-0.70.40.10.50.1-0.1-0.00.1-0.0-0.1-0.10.10.1
Progressive ratio test 2 active lever presses0.40.41.0-0.9-0.9-1.0-0.41.00.9-0.50.90.40.5-0.60.3-0.6-0.40.5-0.6-0.6-0.5-0.2
Progressive ratio test 2 breakpoint0.60.71.2-0.9-0.9-1.1-0.11.11.0-0.21.10.60.6-0.90.6-1.0-0.70.8-0.9-0.9-0.8-0.5
Progressive ratio test 2 inactive lever presses1.21.42.6-1.5-1.5-1.5-0.41.61.2-0.41.51.21.5-1.10.9-1.2-0.91.0-1.2-1.2-1.0-0.7
Incentive Sensitization - Responses0.20.20.60.0-0.00.0-0.40.1-0.1-0.5-0.2-0.7-0.80.4-0.70.30.5-0.50.30.30.40.6
Incentive Sensitization - Breakpoint0.20.20.70.10.00.1-0.40.0-0.2-0.5-0.3-0.8-0.80.5-0.70.30.6-0.60.40.40.50.7
Sum of active levers in priming session hrs 5-60.30.30.80.70.80.60.9-0.9-0.50.9-0.60.60.30.20.3-0.00.0-0.0-0.0-0.0-0.0-0.3
Progressive ratio0.40.41.31.01.00.91.1-1.0-0.81.0-0.7-0.0-0.60.20.50.3-0.10.00.20.2-0.4-0.3
Food seeking constrained by brief footshock1.92.44.71.51.91.90.5-2.0-2.20.1-1.8-1.1-1.41.9-1.31.61.5-1.61.51.51.51.1
Seeking ratio, punishment vs. effort0.60.71.80.10.40.5-0.6-0.4-0.7-0.8-0.5-0.7-0.51.1-1.30.71.1-1.10.80.81.31.0
Retroperitoneal fat weight0.41.56.30.10.90.12.5-0.6-0.52.10.72.10.9-0.71.0-1.1-1.01.0-1.1-1.1-1.1-1.2
Reaction time number correct0.71.03.1-1.7-1.6-1.3-1.71.11.1-1.70.8-0.11.1-0.4-0.50.30.2-0.20.30.30.20.8
Reaction time mean minus median0.40.51.3-1.1-1.0-1.0-0.51.10.7-0.51.10.20.1-0.5-0.2-0.7-0.40.4-0.7-0.7-0.30.0
Reaction time mean minus median AUC0.81.02.9-1.7-1.6-1.5-0.71.51.0-0.71.60.70.7-0.80.4-0.8-0.60.7-0.8-0.8-0.7-0.1
Reaction time num false alarms0.71.02.4-1.6-1.1-1.5-0.01.11.1-0.11.41.00.5-1.40.9-0.9-0.80.8-0.9-0.9-0.9-0.3
Reaction time num false alarms AUC0.60.82.5-1.6-1.3-1.5-0.61.21.1-0.61.20.60.5-1.10.5-0.5-0.50.5-0.6-0.6-0.60.0
Reaction time trials correct on left0.71.03.1-1.7-1.6-1.3-1.71.11.1-1.70.8-0.11.1-0.4-0.50.30.2-0.20.30.30.20.8
Reaction time trials on left0.71.03.1-1.8-1.6-1.4-1.61.21.1-1.70.9-0.01.1-0.5-0.40.20.0-0.10.20.20.10.7
Reaction time mean2.23.16.2-2.3-2.2-2.4-0.62.42.3-0.42.51.31.0-2.01.0-1.8-1.61.7-1.8-1.8-1.5-0.9
Reaction time mean AUC2.33.16.0-2.3-2.2-2.3-0.62.42.4-0.52.51.41.2-2.01.1-1.7-1.61.7-1.7-1.7-1.5-0.9
Median of all reaction times2.63.56.5-2.4-2.2-2.5-0.62.42.5-0.42.51.61.3-2.21.2-1.8-1.71.8-1.9-1.9-1.6-1.1
Reaction time omissions1.31.83.9-1.3-1.1-1.70.61.51.60.42.00.8-0.1-1.60.6-1.7-1.41.3-1.7-1.7-1.5-0.9
Reaction time false alarm rate0.10.20.4-0.6-0.4-0.60.10.50.50.10.60.50.0-0.60.6-0.4-0.30.4-0.4-0.4-0.4-0.2
Reaction time premature initiation rate4.86.511.02.83.03.30.8-3.3-3.20.4-3.3-1.6-1.93.0-2.52.42.6-2.62.42.42.61.7
Reaction time premature initiations2.83.95.91.72.02.30.0-2.4-2.3-0.4-2.4-1.4-1.12.4-2.42.12.2-2.22.12.12.21.7
Std. dev. reaction times0.60.92.2-1.2-1.2-1.3-0.31.41.0-0.31.50.4-0.1-0.90.1-1.2-0.80.8-1.2-1.2-0.7-0.3
Reaction time trials completed0.71.03.1-1.8-1.6-1.4-1.61.21.1-1.70.9-0.01.1-0.5-0.40.20.0-0.10.20.20.10.7
Reaction time trials AUC0.71.03.2-1.8-1.6-1.5-1.51.31.2-1.61.00.11.2-0.6-0.2-0.0-0.10.1-0.0-0.0-0.10.5
Run reversals in cocaine runway, females2.82.74.4-1.0-0.7-1.31.41.11.11.41.81.91.0-1.71.9-2.1-1.91.9-2.0-2.0-2.1-1.7
Run reversals in cocaine runway, males0.40.41.2-0.4-0.8-0.7-0.41.10.7-0.30.7-0.6-0.7-0.70.0-0.5-0.50.5-0.5-0.5-0.6-0.2
Latency to leave start box in cocaine runway1.21.33.00.10.3-0.21.70.20.11.70.91.20.1-1.01.0-1.6-1.31.3-1.6-1.6-1.3-1.4
Latency to leave start box in cocaine runway, F1.21.42.3-0.4-0.5-0.80.90.80.90.91.21.31.0-1.21.4-1.4-1.51.5-1.4-1.4-1.4-1.5
Latency to leave start box in cocaine runway, M1.51.45.11.52.01.52.3-1.6-1.82.1-0.80.5-1.20.6-0.4-0.40.1-0.2-0.4-0.40.1-0.4
Std. dev. time between licks in bursts1.01.22.31.31.51.40.6-1.4-1.50.4-1.5-0.5-1.01.0-0.91.00.9-0.91.01.01.00.6
Total sessions with >9 infusions1.61.75.2-2.3-2.1-1.8-2.31.51.8-2.31.20.11.5-0.5-0.00.10.10.00.10.10.10.6
Short access day 1 total inactive lever presses0.10.10.40.30.50.50.7-0.3-0.60.2-0.10.2-0.10.5-0.1-0.20.1-0.1-0.2-0.20.1-0.2
Short access day 10 total inactive lever presses1.21.42.40.60.81.2-0.5-1.2-1.2-0.7-1.3-0.8-0.21.6-1.11.51.5-1.41.51.51.51.1
Short access day 1 total infusions1.51.65.0-2.2-2.0-1.8-1.81.71.9-1.91.50.31.3-0.70.2-0.3-0.30.4-0.4-0.4-0.30.3
Short access day 10 total infusions0.20.21.1-0.2-0.0-0.20.50.20.10.30.31.11.1-0.20.4-0.6-0.30.4-0.5-0.5-0.4-0.6
Short access total infusions0.10.10.4-0.6-0.5-0.5-0.20.50.4-0.50.50.20.3-0.1-0.0-0.3-0.10.1-0.3-0.3-0.1-0.0
Short access day 1 locomotion1.01.03.1-1.8-1.6-1.5-1.21.31.5-1.31.30.41.2-0.70.4-0.3-0.50.5-0.4-0.4-0.5-0.0
Short access day 10 total locomotion1.01.16.8-1.5-1.3-1.2-0.91.01.1-0.70.91.72.6-0.70.8-0.4-0.40.4-0.4-0.4-0.4-0.4
Short access total locomotion1.41.56.2-2.0-1.7-1.6-1.61.31.5-1.51.11.22.5-0.60.6-0.2-0.20.3-0.2-0.2-0.2-0.0
One hour access (0.3 mA shock)0.00.00.1-0.2-0.2-0.1-0.20.2-0.0-0.30.00.20.30.1-0.3-0.10.1-0.1-0.1-0.10.10.2
Compulsive drug intake2.12.13.70.10.10.6-1.8-0.7-0.7-1.7-1.3-1.6-0.61.5-1.71.81.8-1.81.81.81.91.9
One hour access (shock baseline)1.11.32.1-0.6-0.6-1.00.71.00.90.81.21.41.0-1.31.2-1.4-1.31.3-1.4-1.4-1.4-1.3
Social response proportion0.91.02.0-0.3-0.2-0.61.00.50.41.01.01.00.2-1.21.3-1.0-1.31.3-1.1-1.1-1.4-1.1
Social responses0.30.41.10.30.40.11.1-0.2-0.31.0-0.00.80.5-0.70.7-0.5-0.60.6-0.5-0.5-0.6-0.7
Social time0.60.81.60.30.20.7-0.7-0.4-0.6-0.9-0.9-1.3-0.50.9-1.10.91.1-1.21.01.01.21.1
Soleus weight0.10.30.70.10.0-0.20.8-0.00.50.70.30.50.3-0.70.6-0.6-0.70.7-0.7-0.7-0.8-0.8
Bone: stiffness0.40.62.50.90.80.51.6-0.5-0.21.60.10.5-0.4-0.10.6-0.7-0.60.6-0.7-0.7-0.8-0.9
Tibialis anterior weight0.10.31.1-1.1-0.6-0.7-0.70.30.6-1.00.5-0.30.2-0.1-0.60.30.4-0.30.40.40.20.8
Time to tail flick, vehicle, before self-admin0.30.31.21.10.70.50.4-0.7-0.50.4-0.6-0.8-1.00.4-0.20.40.0-0.00.40.4-0.1-0.2
Time to tail flick, vehicle, after self-admin1.61.75.22.01.71.22.2-1.2-0.92.2-0.7-0.6-2.3-0.20.6-0.6-0.90.9-0.5-0.5-0.9-1.1
Time to tail flick, test, before self-admin0.90.91.9-1.1-1.0-1.10.11.30.9-0.01.40.50.3-0.90.6-1.2-0.80.8-1.2-1.2-0.9-0.5
Time to tail flick, test, after self-admin0.20.20.80.60.60.40.6-0.4-0.40.6-0.2-0.3-0.90.1-0.3-0.1-0.10.0-0.1-0.1-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.50.52.70.90.90.91.0-0.7-0.80.9-0.4-0.6-1.60.2-0.3-0.1-0.00.0-0.1-0.10.0-0.0
Delta time to tail flick, test, before/after SA0.10.10.30.20.30.2-0.1-0.2-0.3-0.1-0.3-0.4-0.40.2-0.50.30.2-0.30.30.30.20.3
Tibia length0.10.41.00.20.00.3-0.7-0.2-0.1-0.6-0.3-0.8-0.31.0-1.00.70.8-0.80.60.60.70.7
Ambulatory time before self-admin1.01.01.9-0.7-0.9-1.10.31.11.00.31.40.40.1-1.01.2-1.3-1.21.2-1.2-1.2-1.1-1.0
Ambulatory time after self-admin0.10.10.30.1-0.30.10.20.4-0.10.10.3-0.1-0.3-0.0-0.2-0.5-0.10.1-0.6-0.6-0.1-0.3
Bone: tissue strength0.30.31.0-1.0-0.6-0.7-0.70.50.5-0.90.6-0.10.00.0-0.20.30.4-0.20.30.30.30.6
Total heroin consumption0.80.93.4-0.10.2-0.11.20.00.11.20.41.81.5-0.71.2-1.0-0.70.7-1.0-1.0-0.9-1.0
Bone: trabecular number2.64.18.02.41.62.4-0.8-1.8-1.9-0.7-2.8-2.8-1.92.3-2.02.12.0-2.02.12.12.11.4
Bone: trabecular spacing2.43.15.8-2.1-1.5-2.10.21.81.90.32.42.31.4-2.11.6-1.7-1.71.8-1.7-1.7-1.8-1.2
Bone: trabecular thickness0.30.31.31.20.80.90.5-0.7-0.90.6-0.8-0.10.40.5-0.20.10.0-0.00.10.10.1-0.4
Bone: trabecular tissue density2.53.55.4-1.1-1.3-1.70.71.71.81.12.21.71.0-2.22.1-2.3-2.32.3-2.3-2.3-2.3-2.0
Water consumed over 24 hours0.60.72.31.51.21.31.2-1.2-1.11.2-1.10.50.20.40.30.00.0-0.00.00.00.0-0.6
Number of responses in last shaping day1.21.33.8-2.0-1.8-1.7-1.71.61.5-1.71.30.10.9-0.70.2-0.3-0.30.3-0.3-0.3-0.30.3