Hub : Genes

Mpped1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_017594994.2 0.05 0.04 3.7e-04 0.01 0.01 0 0.01 7.0e-03 2.4e-02 1.4e-01 2.5e-02
2 PL gene expression Mpped1 0.06 0.04 5.9e-11 0.1 0.1 0.1 0.09 9.6e-11 5.2e-11 5.9e-11 1.6e-10
3 Brain gene expression Mpped1 0.09 0.05 5.6e-11 0.12 0.12 0.11 0.11 3.7e-11 8.5e-11 1.3e-10 1.4e-10
4 NAcc gene expression Mpped1 0.08 0.06 1.2e-10 0.09 0.08 0.08 0.08 2.6e-10 5.9e-10 6.8e-10 6.3e-10
5 Liver alternative TSS XM_017594994.2 0.04 0.03 2.3e-04 0.02 0.01 0.02 0.02 1.0e-03 7.9e-03 3.1e-03 4.0e-03
6 Liver gene expression Mpped1 0.36 0.09 0.0e+00 0.41 0.43 0.43 0.43 1.4e-49 2.2e-51 1.4e-51 1.6e-51
7 Liver alternative TSS XM_017594993.2 0.03 0.02 5.5e-04 0.01 0.02 0.01 0.02 1.8e-02 4.7e-03 3.6e-02 2.2e-03
8 Brain alternative TSS XM_017594993.2 0.04 0.04 6.1e-04 0.04 0.02 0.01 0.01 2.3e-04 3.2e-03 1.9e-02 3.1e-02
9 Liver alternative polyA XM_039079606.1 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 2.1e-03 4.1e-03 6.5e-02 2.8e-03
10 Liver alternative polyA XM_039079608.1 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 2.1e-03 3.7e-03 5.2e-02 2.7e-03
11 IL gene expression Mpped1 0.25 0.15 1.2e-03 0.09 0.06 0.1 0.08 3.1e-03 1.2e-02 2.5e-03 5.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.40.60.7-0.70.70.60.7-0.6-0.6-0.50.8-0.80.6
Area under the delay curve2.32.52.91.7-1.61.71.61.4-1.5-1.5-1.51.6-1.61.6
BMI with tail1.65.35.9-2.32.4-2.3-2.3-2.32.42.22.4-2.32.3-1.9
BMI without tail0.61.21.7-1.11.3-1.1-1.2-1.11.11.21.3-1.11.1-0.2
Body weight1.14.88.3-2.22.4-2.2-2.1-2.22.22.91.9-2.02.0-1.8
Weight adjusted by age0.10.20.5-0.50.4-0.5-0.2-0.30.40.40.7-0.30.30.1
Bone surface0.00.00.10.2-0.10.20.10.1-0.10.2-0.10.1-0.1-0.2
Bone volume0.00.00.00.2-0.10.20.10.1-0.10.1-0.00.2-0.2-0.1
Breakpoint value in progressive ratio session0.00.00.2-0.10.3-0.1-0.1-0.10.20.50.3-0.10.1-0.1
Number of licking bursts0.20.31.30.4-0.40.40.40.4-0.4-0.3-1.20.4-0.40.5
Context. condit. distance diff. score6.27.48.7-2.82.8-2.8-2.9-2.92.92.42.3-2.82.8-2.4
Locomotion velocity, session 11.11.23.2-1.11.0-1.1-1.0-0.90.91.11.8-0.80.8-1.0
Locomotion distance, session 10.10.10.40.0-0.40.00.20.2-0.3-0.60.10.6-0.60.3
Locomotion velocity, session 21.41.64.7-1.41.3-1.4-1.1-1.11.11.02.2-1.21.2-0.1
Locomotion distance, session 20.71.01.60.7-1.10.71.01.0-1.1-1.3-0.01.3-1.30.9
Locomotion velocity, session 31.11.22.5-1.21.1-1.2-1.1-1.11.10.81.6-1.11.1-0.2
Locomotion distance, session 30.60.72.30.6-0.70.60.70.6-0.6-1.2-0.40.7-0.71.5
Stereotopy head waving bouts, day 31.11.23.9-1.01.1-1.0-0.7-0.90.81.22.0-1.11.1-0.9
Stereotopy head waving duration, day 35.16.17.8-2.52.5-2.5-2.2-2.32.32.82.7-2.52.5-2.2
Locomotion velocity, session 70.10.10.2-0.40.3-0.4-0.4-0.30.3-0.00.4-0.30.30.3
Locomotion distance, session 70.70.91.90.8-0.90.80.80.8-0.9-1.4-0.51.0-1.01.2
Stereotopy head waving bouts, day 75.56.27.8-2.72.6-2.7-2.4-2.52.52.82.7-2.42.4-1.7
Stereotopy head waving duration, day 73.23.95.3-2.12.1-2.1-2.0-2.02.02.31.9-2.02.0-1.3
Locomotion velocity, session 88.09.614.9-3.33.1-3.3-3.0-3.13.03.03.9-2.82.8-2.6
Locomotion distance, session 81.62.34.0-1.71.5-1.7-1.6-1.61.51.32.0-1.21.2-1.1
Degree of sensitization distance0.70.71.8-0.70.8-0.7-0.8-0.80.80.90.9-0.80.8-1.3
Degree of sensitization stereotypy3.84.25.0-2.22.1-2.2-2.2-2.22.12.21.9-2.02.0-1.4
Conditioned locomotion0.10.10.80.10.00.1-0.0-0.10.00.4-0.9-0.10.1-0.4
Cocaine response after cond. corrected0.00.00.1-0.30.1-0.3-0.3-0.30.2-0.2-0.2-0.00.00.3
Cocaine response after cond. not corrected0.10.10.1-0.40.2-0.4-0.4-0.30.3-0.1-0.2-0.10.10.4
Cocaine response before conditioning0.10.10.20.3-0.30.30.30.3-0.3-0.3-0.40.2-0.20.2
Saline control response0.10.10.6-0.30.4-0.3-0.2-0.20.30.8-0.0-0.40.4-0.3
Bone: connectivity density0.10.20.30.5-0.40.50.40.5-0.4-0.3-0.40.4-0.40.3
Bone: cortical apparent density1.41.92.41.5-1.51.51.41.4-1.4-1.4-1.11.5-1.50.8
Bone: cortical area1.32.03.0-1.51.5-1.5-1.4-1.41.51.70.7-1.31.3-1.4
Bone: cortical porosity0.40.51.0-0.70.6-0.7-0.5-0.60.60.70.3-1.01.0-0.5
Bone: cortical porosity0.91.01.6-1.01.0-1.0-0.9-0.91.01.10.6-1.31.3-0.8
Bone: cortical thickness0.10.20.80.2-0.20.20.30.3-0.20.5-0.60.0-0.0-0.9
Bone: cortical thickness0.30.31.1-0.50.5-0.5-0.4-0.50.50.70.1-0.50.5-1.1
Bone: cortical tissue density1.31.72.21.5-1.41.51.41.3-1.3-1.4-0.91.4-1.40.8
Condit. Reinf. active minus inactive responses1.72.02.71.2-1.51.21.51.4-1.4-1.1-1.61.6-1.61.0
Condit. Reinf. active-inactive response ratio0.10.21.30.1-0.20.10.10.1-0.10.3-1.20.0-0.0-0.4
Condit. Reinf. active responses3.74.65.91.9-2.21.92.22.1-2.2-2.1-1.92.4-2.42.1
Condit. Reinf. inactive responses3.34.05.01.8-2.01.82.02.1-2.1-2.2-0.92.2-2.22.2
Incentive salience index mean2.73.34.01.7-1.91.72.01.9-1.9-1.5-1.82.0-2.01.4
Condit. Reinf. lever presses2.53.33.91.8-1.91.82.01.9-2.0-1.6-1.22.0-2.01.7
Condit. Reinf. active minus inactive responses0.10.11.0-0.00.0-0.00.10.0-0.00.50.2-0.00.0-1.0
Condit. Reinf. active-inactive response ratio0.10.10.6-0.10.1-0.1-0.0-0.10.10.50.20.0-0.0-0.8
Condit. Reinf. active responses0.71.02.9-0.80.8-0.8-0.8-0.70.81.31.2-0.90.9-1.7
Condit. Reinf. inactive responses1.01.22.2-0.91.0-0.9-1.0-0.91.01.11.4-1.21.2-1.5
Condit. Reinf. lever presses0.10.10.50.3-0.30.30.40.4-0.4-0.30.70.3-0.30.0
Condit. Reinf. lever reinforcers received0.20.31.5-0.20.3-0.2-0.2-0.20.20.70.8-0.30.3-1.2
Conditioned reinforcement - actives0.30.30.50.5-0.60.50.60.7-0.6-0.6-0.60.6-0.60.1
Conditioned reinforcement - inactives0.00.00.1-0.1-0.1-0.1-0.00.0-0.0-0.30.20.1-0.10.3
Conditioned locomotion0.70.81.5-1.01.0-1.0-0.9-0.80.90.81.2-0.80.8-0.4
Patch foraging indifference point 0 sec0.10.20.20.3-0.40.40.50.5-0.4-0.3-0.30.4-0.40.4
Patch foraging indifference point AUC0.20.20.30.6-0.50.60.50.4-0.5-0.5-0.30.2-0.2-0.0
Delay disc. indifference point, 0s delay0.20.20.4-0.30.5-0.4-0.5-0.60.50.40.3-0.50.5-0.2
Delay disc. indifference point, 16s delay4.24.24.92.1-2.12.22.22.0-2.2-2.0-1.52.1-2.12.0
Delay disc. indifference point, 2s delay0.40.50.70.7-0.70.70.60.7-0.6-0.7-0.90.6-0.60.8
Delay disc. indifference point, 24s delay0.80.71.21.1-0.91.10.80.8-0.8-0.7-0.50.9-0.90.8
Delay disc. indifference point, 4s delay0.10.10.50.3-0.40.30.2-0.0-0.2-0.5-0.20.3-0.30.7
Delay disc. indifference point, 8s delay3.33.43.71.9-1.91.91.81.8-1.8-1.9-1.91.9-1.91.8
Indifference point function ln k1.11.52.3-1.11.4-1.2-1.2-1.21.31.51.2-1.11.1-0.7
Indifference point function log k1.11.52.3-1.11.4-1.2-1.2-1.21.31.51.2-1.11.1-0.7
Patch foraging total patch changes 0 sec0.10.20.30.4-0.40.40.50.5-0.5-0.4-0.50.4-0.40.5
Patch foraging total patch changes 12 sec0.10.10.3-0.20.2-0.2-0.2-0.30.30.20.2-0.50.5-0.6
Patch foraging total patch changes 18 sec0.20.20.40.6-0.50.60.60.6-0.50.0-0.70.4-0.4-0.2
Patch foraging total patch changes 24 sec0.10.10.50.3-0.30.30.20.3-0.4-0.50.20.3-0.30.7
Patch foraging total patch changes 6 sec0.00.00.30.0-0.10.10.10.1-0.00.1-0.4-0.10.1-0.5
Patch foraging time to switch 0 sec0.30.51.00.6-0.60.60.70.8-0.7-0.70.30.7-0.71.0
Patch foraging water rate 0 sec0.81.21.7-1.21.1-1.2-1.3-1.31.20.80.4-1.21.2-0.8
Patch foraging water rate 12 sec0.71.01.4-1.11.1-1.1-1.1-1.01.10.80.8-1.21.2-0.0
Patch foraging water rate 18 sec0.00.00.1-0.3-0.0-0.4-0.1-0.20.0-0.2-0.20.1-0.10.1
Patch foraging water rate 24 sec1.52.13.7-1.31.5-1.3-1.1-1.31.31.91.4-1.51.5-1.3
Patch foraging water rate 6 sec0.10.20.40.2-0.40.20.40.3-0.3-0.4-0.60.4-0.40.7
Seeking ratio, delayed vs. immediate footshock1.82.13.01.5-1.61.51.51.7-1.5-1.6-1.21.1-1.11.2
Distance traveled before self-admin0.10.10.20.3-0.20.30.10.10.0-0.40.1-0.30.3-0.4
Distance traveled after self-admin0.30.41.0-0.30.5-0.3-0.4-0.50.50.51.0-0.90.9-0.4
Extensor digitorum longus weight0.00.20.5-0.30.4-0.3-0.2-0.30.4-0.10.7-0.40.40.6
Bone: elastic displacement1.41.61.9-1.41.4-1.4-1.3-1.31.31.31.3-1.21.2-0.8
Bone: elastic work4.96.47.9-2.72.7-2.7-2.6-2.62.62.52.8-2.42.4-1.7
Bone: endosteal estimation3.06.69.1-2.92.7-2.9-2.8-2.92.81.93.0-2.32.3-1.1
Bone: endosteal perimeter2.24.65.9-2.42.3-2.4-2.4-2.42.32.02.2-2.02.0-0.8
Epididymis fat weight0.71.73.1-1.31.3-1.3-1.0-1.11.11.80.9-1.41.4-1.5
Delta time in closed arm before/after self-admin0.00.00.00.0-0.0-0.0-0.1-0.10.0-0.10.20.0-0.00.0
Delta time in open arm before/after self-admin0.50.50.8-0.90.7-0.8-0.8-0.80.80.10.8-0.80.80.2
Diff in mean of infusions in LGA sessions0.91.01.50.9-1.21.01.00.9-1.0-1.2-0.81.1-1.10.5
Delay discount exponential model param2.22.32.7-1.61.6-1.6-1.5-1.41.51.41.5-1.51.5-1.6
Extinction: sum of active levers before priming0.10.10.50.2-0.30.20.20.1-0.2-0.7-0.20.6-0.60.2
Active lever presses in extinction session 60.60.60.9-0.90.7-1.0-0.8-0.90.80.70.1-0.70.7-0.9
Bone: final force1.01.52.1-1.41.2-1.4-1.3-1.21.31.21.1-1.01.0-1.5
Bone: final moment1.62.63.3-1.81.5-1.8-1.7-1.61.61.61.5-1.41.4-1.8
Food consumed during 24 hour testing period2.83.43.7-1.91.8-1.9-1.9-1.91.91.71.6-1.81.8-1.9
Glucose0.81.23.01.2-1.21.21.11.1-1.1-1.0-1.70.7-0.70.5
Heart weight1.82.53.4-1.51.6-1.5-1.7-1.61.71.80.5-1.61.6-1.8
Delay discount hyperbolic model param1.61.72.0-1.41.3-1.3-1.3-1.11.21.31.3-1.31.3-1.4
Intermittent access intake day 1-15 change0.70.71.00.7-0.90.71.01.0-1.0-0.9-0.70.8-0.80.7
Intermittent access intake escalation0.50.50.70.6-0.80.60.80.8-0.8-0.7-0.70.6-0.60.7
Intermittent access intake escalation 20.10.10.20.1-0.50.10.50.5-0.4-0.5-0.40.2-0.20.2
Intermitt. access day 1 inactive lever presses1.21.31.7-1.21.1-1.2-1.3-1.31.20.81.2-1.11.1-0.6
Intermitt. access day 15 inactive lever presses0.91.01.4-1.00.9-1.0-1.0-1.10.90.91.1-0.80.8-1.2
Intermitt. access escalation Index0.10.10.3-0.0-0.2-0.00.30.3-0.3-0.30.20.3-0.30.6
Intermittent access day 1 total infusions0.50.60.7-0.80.8-0.8-0.9-0.80.80.80.8-0.60.6-0.8
Intermittent access day 15 total infusions0.10.10.2-0.50.3-0.5-0.2-0.20.20.10.3-0.20.2-0.2
Intermittent access terminal intake (last 3 days)0.10.10.2-0.50.1-0.5-0.2-0.10.2-0.30.5-0.20.20.1
Intermittent access total infusions0.30.30.6-0.80.5-0.8-0.6-0.60.60.20.6-0.50.5-0.2
Intermittent access day 1 locomotion0.00.00.0-0.10.2-0.1-0.2-0.10.20.10.10.0-0.00.1
Intermittent access day 15 total locomotion0.20.20.4-0.60.6-0.6-0.5-0.50.50.20.6-0.40.40.0
Intermittent access total locomotion0.40.40.6-0.70.7-0.7-0.7-0.60.70.30.8-0.70.7-0.1
Intermittent access standard deviation0.50.61.0-1.00.7-1.0-0.7-0.80.70.41.0-0.70.7-0.4
Left kidney weight13.237.244.7-6.36.4-6.3-6.0-6.06.06.66.7-5.75.7-5.1
Right kidney weight15.443.249.5-6.86.9-6.8-6.6-6.66.56.97.0-6.36.3-5.6
Cocaine induced anxiety3.33.84.4-1.92.0-1.9-2.1-2.12.01.72.1-2.12.1-1.5
Post-drug Anxiety2.02.32.6-1.41.6-1.4-1.6-1.61.61.51.4-1.51.5-1.3
Baseline Anxiety3.03.23.81.9-1.71.91.91.9-1.9-1.2-1.92.0-2.01.2
Tail length0.10.20.30.5-0.30.50.40.5-0.50.2-0.60.5-0.50.4
Length with tail0.10.21.4-0.40.5-0.4-0.3-0.30.31.20.1-0.30.3-0.5
Length without tail0.20.51.1-0.70.6-0.7-0.5-0.60.60.90.8-0.50.5-1.0
Times rat made contact with spout1.82.12.4-1.41.4-1.4-1.4-1.41.51.51.0-1.51.5-1.4
Lifetime Intake0.70.71.1-1.00.8-1.0-0.9-0.90.90.60.9-0.90.9-0.5
Liver weight, left0.10.20.7-0.30.4-0.3-0.3-0.30.30.90.6-0.30.3-0.8
Liver weight, right0.10.20.9-0.20.4-0.2-0.2-0.30.31.00.2-0.30.3-0.4
Locomotor activity2.23.44.5-2.01.9-2.0-1.9-1.92.02.11.4-1.71.7-1.6
Locomotor testing distance0.00.00.1-0.30.0-0.2-0.2-0.20.1-0.0-0.00.2-0.20.1
Locomotor testing rearing0.40.60.8-0.90.8-0.9-0.8-0.80.80.80.5-0.70.7-0.6
Locomotion in novel chamber0.30.41.60.6-0.50.60.70.5-0.7-0.7-0.20.4-0.41.3
Locomotion in novel chamber post-restriction0.81.01.40.9-1.00.90.91.0-0.9-1.1-0.90.9-0.91.2
Fecal boli incidents, locomotor time 10.20.20.50.7-0.30.70.20.2-0.2-0.4-0.10.2-0.20.6
Change in fecal boli incidents, locomotor task0.40.40.6-0.60.7-0.6-0.7-0.60.60.80.1-0.60.6-0.5
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.1-0.2-0.1-0.20.1-0.20.6-0.00.00.4
Bouts of movement, locomotor time 10.10.10.20.3-0.40.30.40.4-0.4-0.3-0.20.2-0.2-0.1
Total resting periods, locomotor time 10.20.30.40.5-0.60.60.60.7-0.6-0.5-0.40.4-0.40.2
Rest time, locomotor task time 10.00.00.2-0.1-0.1-0.00.10.1-0.1-0.20.4-0.10.10.1
Distance moved, locomotor task time 10.10.10.2-0.30.3-0.4-0.2-0.20.20.50.40.0-0.00.0
Vertical activity count, locomotor time 10.00.00.00.00.1-0.1-0.2-0.10.10.1-0.00.1-0.10.2
Time >=10cm from walls, locomotor time 20.40.51.30.7-0.60.60.60.6-0.6-0.7-0.40.6-0.61.1
Bouts of movement, locomotor time 20.40.41.70.6-0.70.60.60.5-0.6-0.4-1.30.5-0.5-0.1
Total resting periods, locomotor time 20.40.41.60.6-0.70.60.70.6-0.6-0.3-1.30.6-0.6-0.3
Rest time, locomotor task time 20.20.20.40.6-0.50.50.60.6-0.6-0.3-0.30.4-0.40.1
Distance moved, locomotor task time 20.70.91.3-1.11.0-1.2-1.0-0.90.90.81.0-0.90.9-0.1
Vertical activity count, locomotor time 20.70.71.1-0.71.0-0.8-1.0-0.90.90.81.0-0.80.8-0.2
Light reinforcement 10.40.72.4-0.71.0-0.7-0.8-0.70.71.01.5-0.50.5-0.1
Light reinforcement 20.40.61.6-0.61.0-0.6-0.7-0.60.61.21.3-0.60.6-0.1
Bone: marrow area3.37.19.5-3.02.8-3.0-3.0-3.02.92.03.1-2.52.5-1.2
Bone: maximum diameter5.710.511.9-3.53.4-3.5-3.4-3.43.43.32.9-3.23.2-2.5
Bone: maximum force2.84.85.6-2.42.2-2.4-2.3-2.22.32.11.8-2.02.0-2.2
Bone: maximum moment3.76.37.4-2.72.5-2.7-2.6-2.62.62.42.1-2.42.4-2.5
Mean time between licks in bursts0.91.32.81.0-1.21.01.11.1-1.0-1.2-1.71.0-1.00.8
Mean num. licks in bursts2.32.74.2-1.61.6-1.6-1.6-1.61.61.62.0-1.61.6-1.5
Cd content in liver1.61.82.5-1.61.2-1.6-1.4-1.41.41.4-0.2-1.31.3-1.3
Co content in liver0.80.91.6-1.01.0-1.0-0.8-0.80.80.91.2-0.80.8-1.2
Cu content in liver6.78.19.12.9-2.92.92.92.9-2.9-2.6-2.52.8-2.83.0
Fe content in liver0.30.30.4-0.70.6-0.7-0.6-0.60.60.50.6-0.60.6-0.1
K content in liver0.40.40.60.6-0.60.60.80.8-0.8-0.40.50.7-0.70.6
Mg content in liver0.90.91.31.0-1.01.01.11.1-1.1-0.7-0.01.1-1.10.9
Mn content in liver0.10.10.7-0.10.3-0.1-0.1-0.10.10.40.9-0.10.1-0.1
Na content in liver2.12.34.41.4-1.71.41.51.5-1.4-1.6-2.11.4-1.41.1
Rb content in liver0.00.00.20.2-0.20.20.10.1-0.10.2-0.50.1-0.1-0.3
Se content in liver1.31.62.11.2-1.21.21.41.4-1.4-1.1-0.21.4-1.41.4
Sr content in liver0.80.70.90.6-0.80.60.90.9-0.9-1.0-0.90.9-0.90.8
Zn content in liver0.91.01.21.0-1.01.01.11.1-1.1-0.9-1.01.0-1.00.9
Bone: minimum diameter0.61.21.6-1.21.2-1.2-1.1-1.11.11.21.3-1.01.0-0.4
Time in familiar zone, hab. session 10.40.41.0-0.80.6-0.8-0.6-0.60.60.31.0-0.40.4-0.1
Time in novel zone, hab. session 10.70.71.2-0.60.8-0.6-0.7-0.80.81.1-0.4-1.01.0-1.1
Total zone transitions, hab. session 11.92.73.21.7-1.71.71.81.7-1.7-1.5-1.51.7-1.71.2
Total locomotion distance, hab. session 10.40.61.00.8-0.60.80.90.9-0.8-0.50.20.8-0.81.0
Locomotion velocity, hab. session 10.60.91.60.9-0.80.91.01.0-1.0-0.80.31.0-1.01.2
Time in familiar zone, hab. session 20.20.20.30.3-0.30.30.40.5-0.4-0.2-0.10.5-0.50.6
Time in novel zone, hab. session 20.90.91.5-0.80.8-0.8-0.9-1.01.00.80.2-1.21.2-1.1
Total zone transitions, hab. session 20.10.10.90.0-0.10.00.10.1-0.1-0.10.90.2-0.2-0.1
Total locomotion distance, hab. session 20.10.20.50.3-0.20.30.30.3-0.3-0.40.70.4-0.40.6
Locomotion velocity, hab. session 20.30.40.60.6-0.50.60.70.7-0.7-0.70.50.7-0.70.8
Novel to familiar place preference ratio2.52.63.7-1.51.6-1.5-1.6-1.51.61.90.8-1.81.8-1.7
Novelty place preference3.33.44.7-1.81.9-1.8-1.9-1.81.82.21.0-2.02.0-1.8
Time in novel zone, NPP test4.64.76.3-2.12.2-2.1-2.2-2.22.22.51.1-2.42.4-2.1
Total zone transitions, NPP test0.30.51.00.5-0.70.50.60.6-0.7-0.9-0.01.0-1.00.6
Total locomotion distance, NPP test0.20.31.10.3-0.30.30.40.3-0.4-0.60.70.6-0.61.0
Locomotion velocity, NPP test1.01.43.01.0-1.01.01.11.1-1.1-1.30.21.4-1.41.7
Intraocular pressure0.40.60.9-0.80.8-0.8-0.9-1.00.90.60.1-0.80.8-0.5
Delta distance traveled before/after self-admin1.81.92.4-1.41.5-1.4-1.4-1.41.31.61.5-1.51.5-0.6
Delta ambulatory time before/after self-admin2.32.54.2-1.61.7-1.6-1.5-1.61.52.11.4-1.71.7-1.0
Parametrial fat weight0.20.30.70.6-0.50.70.70.8-0.7-0.4-0.10.5-0.50.4
Pavlov. Cond. lever latency3.03.84.7-2.02.0-2.0-2.2-2.12.11.71.4-2.12.1-1.6
Pavlov. Cond. magazine entry latency2.73.54.61.9-2.01.92.02.0-2.0-1.8-2.11.8-1.81.0
Pavlov. Cond. change in total contacts3.13.33.91.9-2.01.92.02.0-1.9-1.6-1.91.7-1.71.0
Pavlov. Cond. index score2.12.73.41.7-1.81.71.81.8-1.8-1.4-1.81.6-1.60.9
Pavlov. Cond. latency score1.72.22.81.5-1.61.51.71.6-1.6-1.3-1.41.5-1.50.9
Pavlov. Cond. lever contacts3.54.15.12.1-2.12.12.32.2-2.2-1.8-1.62.1-2.11.7
Pavlov. Cond. magazine entry number2.73.35.1-1.92.0-1.9-2.0-1.91.91.62.3-1.71.7-0.8
Pavlov. Cond. intertrial magazine entries0.30.40.70.6-0.60.60.60.6-0.6-0.8-0.30.6-0.60.8
Pavlov. Cond. lever-magazine prob. diff.2.83.54.21.9-2.01.92.12.0-2.0-1.7-2.01.8-1.81.1
Pavlov. Cond. response bias4.25.06.02.3-2.42.32.42.4-2.4-2.0-2.42.2-2.21.5
Pavlov. Cond. lever latency0.20.30.6-0.60.5-0.6-0.7-0.70.60.4-0.5-0.50.5-0.3
Pavlov. Cond. magazine entry latency2.93.44.12.0-2.02.02.02.0-2.0-2.0-0.81.8-1.81.6
Pavlov. Cond. change in total contacts0.20.30.70.5-0.50.50.60.6-0.6-0.30.80.5-0.5-0.2
Pavlov. Cond. index score1.31.72.41.4-1.41.41.51.6-1.5-1.3-0.11.3-1.31.0
Pavlov. Cond. latency score1.62.02.71.5-1.51.51.61.6-1.6-1.4-0.21.4-1.41.1
Pavlov. Cond. lever contacts0.20.30.50.6-0.50.60.60.7-0.6-0.40.60.5-0.50.2
Pavlov. Cond. magazine entry number1.82.22.7-1.61.5-1.6-1.6-1.61.61.60.2-1.51.5-1.2
Pavlov. Cond. intertrial magazine entries2.43.24.6-1.81.8-1.8-1.8-1.81.91.91.0-1.81.8-2.1
Pavlov. Cond. lever-magazine prob. diff.1.62.02.81.5-1.51.51.61.7-1.6-1.4-0.11.4-1.41.1
Pavlov. Cond. response bias0.50.71.21.0-0.91.01.01.1-1.0-0.70.20.7-0.70.4
Time in closed arm before self-admin2.32.63.21.5-1.71.61.71.8-1.7-1.7-1.51.6-1.61.3
Time in closed arm after self-admin0.20.20.30.5-0.40.40.50.6-0.5-0.1-0.50.5-0.50.3
Time in open arm before self-admin0.10.20.70.3-0.30.30.10.1-0.2-0.3-0.40.4-0.40.8
Time in open arm after self-admin0.30.30.6-0.60.5-0.5-0.6-0.60.5-0.30.7-0.40.40.7
Bone: periosteal estimation3.06.27.6-2.82.6-2.8-2.7-2.72.72.42.4-2.32.3-1.6
Bone: periosteal perimeter3.25.36.3-2.52.5-2.5-2.5-2.42.52.51.7-2.32.3-1.5
Bone: post-yield work0.81.12.1-1.10.8-1.1-1.2-1.11.10.70.1-1.01.0-1.4
Progressive ratio test 1 active lever presses0.00.00.00.2-0.10.20.10.2-0.10.1-0.20.2-0.2-0.1
Progressive ratio test 1 breakpoint0.20.20.20.5-0.40.50.40.5-0.4-0.3-0.40.5-0.50.2
Progressive ratio test 1 inactive lever presses0.10.10.1-0.20.2-0.2-0.3-0.30.2-0.10.3-0.30.30.2
Progressive ratio test 2 active lever presses0.30.30.9-0.80.4-0.8-0.5-0.50.5-0.00.9-0.40.4-0.4
Progressive ratio test 2 breakpoint0.30.30.8-0.80.4-0.8-0.5-0.50.50.10.9-0.40.4-0.6
Progressive ratio test 2 inactive lever presses0.10.10.5-0.30.1-0.3-0.2-0.20.2-0.20.7-0.10.1-0.1
Incentive Sensitization - Responses1.31.33.0-1.41.0-1.4-1.1-1.11.10.41.7-1.11.1-0.8
Incentive Sensitization - Breakpoint1.61.63.6-1.61.1-1.6-1.2-1.21.20.51.9-1.21.2-0.9
Sum of active levers in priming session hrs 5-60.10.10.3-0.30.2-0.2-0.3-0.40.2-0.30.5-0.20.20.1
Progressive ratio0.10.10.30.3-0.50.30.40.4-0.3-0.4-0.60.3-0.3-0.0
Food seeking constrained by brief footshock0.60.71.3-0.80.9-0.8-0.7-0.60.71.21.1-0.70.7-1.0
Seeking ratio, punishment vs. effort0.40.51.1-0.60.7-0.6-0.6-0.60.60.81.1-0.50.5-0.6
Retroperitoneal fat weight0.61.94.2-1.31.5-1.3-1.1-1.11.12.01.7-1.31.3-1.3
Reaction time number correct1.21.82.21.2-1.41.11.31.3-1.5-1.2-1.41.4-1.41.4
Reaction time mean minus median0.30.40.7-0.60.6-0.6-0.6-0.70.60.6-0.1-0.70.7-0.8
Reaction time mean minus median AUC0.91.11.7-1.11.0-1.1-1.1-1.11.10.90.5-1.31.3-1.0
Reaction time num false alarms0.10.10.7-0.30.1-0.3-0.1-0.10.10.3-0.80.1-0.1-0.0
Reaction time num false alarms AUC0.10.10.4-0.40.1-0.3-0.2-0.20.20.3-0.60.1-0.1-0.1
Reaction time trials correct on left1.21.82.21.2-1.41.11.31.3-1.5-1.2-1.41.4-1.41.4
Reaction time trials on left1.31.92.31.2-1.41.21.31.3-1.5-1.3-1.51.4-1.41.4
Reaction time mean0.10.10.40.3-0.30.30.30.3-0.2-0.2-0.60.0-0.0-0.3
Reaction time mean AUC0.10.10.40.4-0.30.40.40.3-0.2-0.1-0.60.0-0.0-0.4
Median of all reaction times0.20.30.50.6-0.60.60.60.5-0.5-0.4-0.70.3-0.3-0.2
Reaction time omissions0.20.31.70.4-0.60.50.40.4-0.5-0.6-1.30.3-0.3-0.1
Reaction time false alarm rate0.30.40.7-0.80.7-0.7-0.7-0.70.80.70.0-0.50.5-0.6
Reaction time premature initiation rate0.10.10.6-0.2-0.0-0.2-0.1-0.0-0.0-0.10.80.2-0.2-0.4
Reaction time premature initiations0.20.30.50.4-0.60.30.50.5-0.7-0.60.00.7-0.70.3
Std. dev. reaction times0.20.20.7-0.30.4-0.3-0.3-0.30.30.6-0.1-0.60.6-0.8
Reaction time trials completed1.31.92.31.2-1.41.21.31.3-1.5-1.3-1.51.4-1.41.4
Reaction time trials AUC1.01.41.71.1-1.21.01.11.2-1.3-1.1-1.21.3-1.31.2
Run reversals in cocaine runway, females2.82.73.92.0-1.52.01.81.9-1.8-1.2-1.51.4-1.41.6
Run reversals in cocaine runway, males1.21.21.5-1.11.1-1.1-1.1-1.11.21.10.3-1.21.2-1.0
Latency to leave start box in cocaine runway0.70.81.4-0.81.0-0.8-1.1-0.91.00.61.2-0.80.8-0.3
Latency to leave start box in cocaine runway, F0.10.10.4-0.20.2-0.2-0.4-0.30.4-0.40.6-0.10.1-0.1
Latency to leave start box in cocaine runway, M1.41.31.7-1.21.3-1.2-1.2-1.21.21.31.2-1.11.1-0.6
Std. dev. time between licks in bursts0.81.01.21.0-1.11.01.11.1-1.1-0.8-0.71.0-1.00.6
Total sessions with >9 infusions0.20.30.6-0.40.6-0.4-0.5-0.40.50.80.4-0.50.5-0.4
Short access day 1 total inactive lever presses3.23.64.0-2.01.9-2.0-1.9-1.91.91.82.0-1.91.9-1.5
Short access day 10 total inactive lever presses3.64.04.9-2.22.1-2.2-2.1-2.22.01.92.1-2.02.0-1.2
Short access day 1 total infusions1.41.52.0-1.21.2-1.2-1.2-1.21.21.11.4-1.41.4-1.0
Short access day 10 total infusions0.10.10.30.2-0.20.20.20.3-0.3-0.1-0.50.5-0.50.4
Short access total infusions0.91.11.2-1.01.0-1.0-1.0-1.01.01.11.0-1.11.1-0.8
Short access day 1 locomotion0.00.00.1-0.00.1-0.0-0.1-0.10.1-0.30.2-0.20.20.2
Short access day 10 total locomotion0.80.91.60.9-1.00.90.80.8-0.8-1.2-1.00.9-0.91.1
Short access total locomotion0.00.00.10.1-0.10.10.00.1-0.1-0.1-0.30.2-0.20.2
One hour access (0.3 mA shock)0.10.20.7-0.2-0.2-0.20.10.1-0.1-0.80.20.3-0.30.8
Compulsive drug intake0.20.20.70.3-0.40.30.10.0-0.2-0.90.20.5-0.50.5
One hour access (shock baseline)0.10.10.6-0.1-0.2-0.10.30.3-0.3-0.5-0.30.2-0.20.8
Social response proportion0.20.20.5-0.20.4-0.2-0.2-0.20.40.40.5-0.70.7-0.1
Social responses0.20.30.60.6-0.50.70.80.7-0.7-0.30.20.4-0.40.5
Social time2.73.64.72.1-2.12.22.02.1-2.0-1.9-2.11.5-1.51.1
Soleus weight0.20.40.6-0.80.5-0.8-0.8-0.80.70.30.7-0.60.6-0.6
Bone: stiffness1.01.63.1-1.41.1-1.4-1.4-1.31.31.30.2-1.11.1-1.8
Tibialis anterior weight0.30.91.60.9-0.80.90.90.9-0.9-1.1-0.11.0-1.01.3
Time to tail flick, vehicle, before self-admin0.10.10.3-0.00.2-0.0-0.2-0.10.10.40.3-0.20.2-0.6
Time to tail flick, vehicle, after self-admin0.30.30.80.3-0.50.40.30.3-0.4-0.9-0.60.4-0.40.9
Time to tail flick, test, before self-admin0.00.00.1-0.20.2-0.1-0.1-0.10.20.30.1-0.10.10.0
Time to tail flick, test, after self-admin2.22.23.91.3-1.61.31.31.4-1.3-2.0-1.21.6-1.61.6
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.60.2-0.5-0.4-0.50.5-0.40.4-0.20.20.0
Delta time to tail flick, test, before/after SA2.21.93.91.2-1.51.21.31.2-1.3-2.0-0.71.5-1.51.5
Tibia length0.72.02.7-1.71.4-1.7-1.5-1.51.41.51.0-1.31.3-1.3
Ambulatory time before self-admin0.10.10.30.1-0.00.1-0.1-0.10.2-0.30.2-0.60.6-0.5
Ambulatory time after self-admin0.30.30.8-0.30.5-0.2-0.4-0.50.50.40.6-0.90.9-0.3
Bone: tissue strength0.50.50.8-0.90.6-0.9-0.8-0.70.70.50.5-0.60.6-0.6
Total heroin consumption0.50.60.8-0.90.7-0.8-0.8-0.80.80.60.6-0.60.6-0.7
Bone: trabecular number0.10.20.80.3-0.40.30.30.3-0.2-0.3-0.90.3-0.30.5
Bone: trabecular spacing0.70.92.1-0.81.0-0.8-0.8-0.90.90.91.5-0.90.9-0.8
Bone: trabecular thickness0.40.50.90.9-0.70.90.90.9-0.9-0.3-0.10.6-0.60.4
Bone: trabecular tissue density0.60.91.40.9-1.00.90.90.9-1.0-1.2-0.41.1-1.10.8
Water consumed over 24 hours4.95.86.4-2.52.4-2.5-2.5-2.52.42.41.8-2.52.5-2.4
Number of responses in last shaping day0.80.91.11.0-1.01.01.01.1-1.0-0.9-0.80.9-0.90.4