Hub : Genes

Mpped1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Mpped1 0.12 0.07 9.3e-15 0.16 0.15 0.16 0.16 4.5e-15 3.8e-14 9.5e-15 4.7e-15
2 BLA isoform ratio XM_017594993.3 0.06 0.04 2.3e-03 -0 0.01 -0 -0 5.1e-01 7.6e-02 7.8e-01 7.3e-01
3 PL gene expression Mpped1 0.06 0.04 1.6e-10 0.09 0.09 0.07 0.09 5.1e-10 2.0e-10 2.3e-08 8.9e-10
4 Liver alternative TSS XM_063263940.1 0.1 0.07 2.3e-09 0.06 0.06 0.07 0.06 5.3e-07 7.3e-07 1.9e-08 7.4e-07
5 PL alternative TSS XM_017594993.3 0.03 0.02 1.7e-03 0.03 0.02 0.02 0.02 6.9e-04 1.2e-03 2.4e-03 2.4e-03
6 IL gene expression Mpped1 0.31 0.18 1.6e-04 0.1 0.1 0.1 0.11 2.5e-03 1.8e-03 2.3e-03 1.4e-03
7 PL alternative TSS XM_017594993.3 0.03 0.02 2.1e-03 0.02 0.02 0.02 0.02 9.6e-04 2.1e-03 4.0e-03 4.1e-03
8 IC gene expression Mpped1 0.2 0.1 5.5e-08 0.17 0.14 0.14 0.15 1.9e-07 1.4e-06 1.5e-06 5.9e-07
9 BLA alternative TSS XM_017594993.3 0.05 0.04 2.7e-03 0.03 0.02 0.01 0 1.2e-02 2.0e-02 6.4e-02 3.0e-01
10 BLA alternative TSS XM_017594993.3 0.05 0.04 3.8e-03 0.02 0.02 0 0 3.0e-02 4.3e-02 2.6e-01 2.0e-01
11 Liver gene expression Mpped1 0.43 0.1 0.0e+00 0.45 0.46 0.46 0.45 5.4e-55 3.8e-56 5.7e-56 2.1e-55
12 Liver alternative polyA XM_039079606.2 0.03 0.03 5.5e-04 0.02 0.02 0.01 0.02 1.9e-03 3.0e-03 7.6e-03 1.9e-03
13 Liver alternative polyA XM_063263938.1 0.04 0.03 4.2e-04 0.02 0.02 0.01 0.02 1.4e-03 2.0e-03 8.5e-03 1.7e-03
14 NAcc gene expression Mpped1 0.09 0.06 3.0e-13 0.07 0.08 0.07 0.08 2.0e-11 1.0e-12 3.3e-11 2.9e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.30.60.9-0.70.8-0.70.90.8-0.90.8-0.60.70.70.7-0.80.8-0.6
Area under the delay curve1.72.03.4-1.31.5-1.51.81.4-1.31.4-1.31.31.31.3-1.51.5-1.1
BMI with tail1.65.77.82.6-2.52.5-2.8-2.01.9-2.02.4-2.4-2.4-2.42.5-2.52.3
BMI without tail0.51.62.71.2-1.31.2-1.7-1.31.2-1.21.5-1.4-1.4-1.01.1-1.10.9
Body weight1.56.48.72.3-2.52.5-3.0-2.72.7-2.72.5-2.8-2.8-2.12.3-2.32.0
Weight adjusted by age0.10.20.40.4-0.50.5-0.7-0.40.4-0.40.4-0.4-0.4-0.20.4-0.40.1
Bone surface0.00.10.2-0.40.3-0.30.50.2-0.10.3-0.40.20.20.3-0.30.3-0.2
Bone volume0.00.10.2-0.40.3-0.30.40.2-0.20.2-0.30.20.20.3-0.30.3-0.2
Breakpoint value in progressive ratio session0.20.20.6-0.1-0.20.2-0.2-0.80.7-0.80.1-0.7-0.70.20.1-0.1-0.2
Number of licking bursts0.10.20.3-0.20.4-0.40.60.3-0.00.1-0.50.30.30.4-0.40.4-0.6
Context. condit. distance diff. score5.76.98.62.7-2.82.8-2.4-2.42.5-2.32.6-2.5-2.5-2.92.8-2.82.8
Locomotion velocity, session 10.80.91.71.2-1.01.0-0.9-0.91.3-0.90.4-0.8-0.8-0.80.9-0.91.0
Locomotion distance, session 10.20.30.8-0.00.4-0.40.30.9-0.50.8-0.80.70.70.2-0.50.5-0.0
Locomotion velocity, session 21.11.32.41.5-1.41.3-1.4-0.91.0-0.81.1-1.1-1.1-0.81.2-1.20.7
Locomotion distance, session 20.91.32.2-0.51.1-1.10.81.5-1.21.4-1.21.21.21.0-1.21.2-0.6
Locomotion velocity, session 30.70.81.91.4-1.21.1-0.9-0.30.6-0.40.7-0.9-0.9-0.91.1-1.10.8
Locomotion distance, session 30.91.02.3-0.40.7-0.70.91.5-1.51.4-1.11.01.00.8-0.70.7-1.0
Stereotopy head waving bouts, day 30.81.01.50.9-1.01.0-1.0-1.11.1-1.11.2-0.9-0.9-0.61.0-1.00.8
Stereotopy head waving duration, day 35.26.28.12.4-2.52.5-2.4-2.62.7-2.62.8-2.4-2.4-2.12.5-2.52.2
Locomotion velocity, session 70.10.10.20.4-0.30.3-0.40.40.00.40.4-0.1-0.1-0.20.3-0.30.1
Locomotion distance, session 70.81.12.2-0.80.9-0.90.81.5-1.31.4-1.01.01.00.8-1.01.0-0.7
Stereotopy head waving bouts, day 74.04.55.72.3-2.32.3-2.4-2.02.2-1.92.0-2.1-2.1-2.02.1-2.11.8
Stereotopy head waving duration, day 73.34.04.72.0-2.22.1-2.0-2.02.1-1.92.2-2.0-2.0-1.82.0-2.01.5
Locomotion velocity, session 87.38.711.43.4-3.13.1-3.0-2.83.1-2.82.5-2.9-2.9-2.92.9-2.93.0
Locomotion distance, session 81.31.93.11.8-1.51.5-1.5-1.11.5-1.11.3-1.2-1.2-1.51.3-1.31.5
Degree of sensitization distance0.90.91.40.6-0.80.8-0.9-1.11.2-1.11.1-0.9-0.9-0.90.8-0.81.2
Degree of sensitization stereotypy3.74.04.92.2-2.22.2-2.2-1.92.0-1.82.0-2.0-2.0-2.02.0-2.01.7
Conditioned locomotion0.00.00.2-0.1-0.10.0-0.0-0.30.4-0.30.2-0.2-0.2-0.10.1-0.1-0.0
Cocaine response after cond. corrected0.00.00.20.1-0.20.2-0.40.10.1-0.0-0.10.20.2-0.30.1-0.10.1
Cocaine response after cond. not corrected0.00.00.10.2-0.30.3-0.30.10.1-0.10.00.20.2-0.30.2-0.2-0.0
Cocaine response before conditioning0.10.10.2-0.20.3-0.30.40.3-0.20.2-0.40.30.30.2-0.20.2-0.3
Saline control response0.20.30.80.5-0.60.5-0.7-0.80.9-0.7-0.1-0.6-0.6-0.30.5-0.50.1
Bone: connectivity density0.10.10.5-0.40.4-0.40.70.4-0.40.4-0.00.20.20.4-0.30.3-0.4
Bone: cortical apparent density2.02.83.8-1.71.7-1.71.61.6-1.91.7-1.81.61.61.6-1.71.7-1.4
Bone: cortical area1.21.92.71.6-1.41.4-1.0-1.51.6-1.41.3-1.4-1.4-1.31.2-1.21.1
Bone: cortical porosity0.20.20.6-0.0-0.40.40.1-0.40.4-0.50.6-0.6-0.6-0.40.8-0.80.2
Bone: cortical porosity1.11.21.90.7-1.11.1-0.5-1.11.2-1.31.2-1.2-1.2-1.01.4-1.40.8
Bone: cortical thickness0.00.10.30.00.3-0.20.5-0.40.4-0.3-0.1-0.3-0.30.2-0.10.1-0.1
Bone: cortical thickness0.40.41.00.6-0.40.5-0.3-0.81.0-0.80.5-0.6-0.6-0.60.6-0.60.8
Bone: cortical tissue density1.82.53.5-1.61.6-1.61.41.5-1.91.6-1.81.51.51.5-1.61.6-1.3
Condit. Reinf. active minus inactive responses2.02.22.7-1.51.6-1.61.41.6-1.61.6-1.51.31.31.3-1.51.5-1.2
Condit. Reinf. active-inactive response ratio0.00.00.1-0.30.3-0.20.40.1-0.20.20.2-0.1-0.1-0.10.0-0.00.0
Condit. Reinf. active responses4.15.16.0-2.22.2-2.22.12.4-2.42.4-2.32.22.22.1-2.32.3-2.1
Condit. Reinf. inactive responses3.54.35.5-1.82.0-2.01.92.1-2.12.0-2.42.22.22.1-2.12.1-2.0
Incentive salience index mean3.03.64.1-2.02.0-2.01.82.0-2.02.0-2.01.71.71.8-1.91.9-1.7
Condit. Reinf. lever presses2.73.84.8-1.81.9-1.91.72.1-1.92.0-2.21.91.92.0-2.02.0-1.8
Condit. Reinf. active minus inactive responses0.00.10.30.10.1-0.10.4-0.30.6-0.3-0.1-0.2-0.20.10.0-0.00.2
Condit. Reinf. active-inactive response ratio0.10.10.40.30.0-0.00.3-0.40.7-0.40.0-0.1-0.1-0.00.0-0.00.2
Condit. Reinf. active responses0.60.82.00.8-0.70.7-0.5-1.11.4-1.10.7-0.9-0.9-0.70.9-0.91.0
Condit. Reinf. inactive responses0.81.11.40.7-1.01.0-0.8-1.01.2-1.11.1-1.0-1.0-1.01.2-1.21.2
Condit. Reinf. lever presses0.10.20.5-0.30.4-0.40.40.4-0.20.4-0.30.70.70.6-0.30.3-0.3
Condit. Reinf. lever reinforcers received0.10.20.80.2-0.10.20.1-0.60.9-0.60.2-0.3-0.3-0.10.3-0.30.5
Conditioned reinforcement - actives0.10.10.30.00.3-0.30.30.5-0.50.5-0.20.30.30.2-0.40.4-0.1
Conditioned reinforcement - inactives0.10.20.50.7-0.30.3-0.7-0.10.1-0.10.7-0.3-0.3-0.40.0-0.00.6
Conditioned locomotion0.30.41.01.0-0.80.8-0.8-0.40.4-0.40.8-0.5-0.5-0.40.6-0.60.4
Patch foraging indifference point 0 sec0.10.10.3-0.50.4-0.40.10.3-0.40.40.20.20.20.5-0.30.3-0.4
Patch foraging indifference point AUC0.40.61.1-0.60.8-0.70.91.1-0.91.0-1.00.80.80.5-0.40.4-0.3
Delay disc. indifference point, 0s delay0.30.30.50.6-0.60.6-0.3-0.50.5-0.50.6-0.7-0.7-0.50.5-0.50.4
Delay disc. indifference point, 16s delay3.23.54.0-2.02.0-2.01.91.8-1.71.8-1.81.91.91.9-2.02.0-1.6
Delay disc. indifference point, 2s delay0.50.51.2-0.40.8-0.81.10.7-0.70.7-0.50.60.60.6-0.70.7-0.5
Delay disc. indifference point, 24s delay0.70.81.2-1.11.0-1.01.00.9-0.80.9-0.80.90.90.8-1.01.0-0.7
Delay disc. indifference point, 4s delay0.20.20.40.00.4-0.40.60.5-0.40.6-0.10.40.40.0-0.40.40.2
Delay disc. indifference point, 8s delay2.73.24.4-1.81.9-1.92.11.8-1.81.8-1.91.71.71.6-1.81.8-1.5
Indifference point function ln k1.01.82.60.8-1.41.4-1.6-1.61.5-1.61.4-1.6-1.6-1.01.1-1.10.7
Indifference point function log k1.01.82.60.8-1.41.4-1.6-1.61.5-1.61.4-1.6-1.6-1.01.1-1.10.7
Patch foraging total patch changes 0 sec0.10.20.4-0.60.5-0.50.30.4-0.50.50.10.30.30.5-0.40.4-0.5
Patch foraging total patch changes 12 sec0.10.10.30.2-0.10.1-0.10.00.00.10.2-0.1-0.1-0.40.5-0.50.5
Patch foraging total patch changes 18 sec0.10.10.6-0.80.5-0.50.30.20.00.2-0.20.00.00.5-0.30.3-0.4
Patch foraging total patch changes 24 sec0.10.20.7-0.40.2-0.30.40.8-0.70.9-0.00.40.40.5-0.30.3-0.6
Patch foraging total patch changes 6 sec0.00.00.1-0.20.2-0.20.20.00.00.00.1-0.1-0.1-0.10.1-0.10.3
Patch foraging time to switch 0 sec0.20.50.8-0.70.5-0.60.60.5-0.50.5-0.70.90.90.9-0.70.7-0.8
Patch foraging water rate 0 sec0.61.33.61.1-1.11.1-1.0-0.80.8-0.81.9-1.1-1.1-1.31.2-1.21.2
Patch foraging water rate 12 sec0.51.02.01.1-1.11.1-1.2-0.70.7-0.71.4-1.0-1.0-0.81.1-1.10.4
Patch foraging water rate 18 sec0.00.00.10.20.1-0.1-0.00.1-0.20.10.00.20.2-0.0-0.30.30.0
Patch foraging water rate 24 sec1.82.64.01.4-1.61.6-1.4-2.01.9-2.01.6-1.8-1.8-1.11.5-1.51.0
Patch foraging water rate 6 sec0.20.20.6-0.40.4-0.40.10.8-0.60.7-0.40.30.30.4-0.40.4-0.6
Seeking ratio, delayed vs. immediate footshock1.82.23.1-1.51.6-1.61.41.7-1.61.6-0.91.41.41.6-1.21.2-1.8
Distance traveled before self-admin0.20.30.5-0.70.6-0.60.60.5-0.50.5-0.30.60.60.5-0.30.3-0.5
Distance traveled after self-admin0.00.10.1-0.1-0.00.0-0.2-0.30.3-0.30.1-0.2-0.20.20.4-0.4-0.1
Extensor digitorum longus weight0.10.20.50.6-0.60.5-0.7-0.1-0.4-0.10.7-0.3-0.3-0.20.5-0.50.0
Bone: elastic displacement1.61.92.31.5-1.51.4-1.1-1.41.4-1.41.5-1.3-1.3-1.31.4-1.41.1
Bone: elastic work4.96.48.52.9-2.72.7-2.5-2.52.4-2.52.7-2.4-2.4-2.42.4-2.42.3
Bone: endosteal estimation2.14.56.82.6-2.62.6-2.5-1.51.7-1.52.2-1.6-1.6-2.42.1-2.12.1
Bone: endosteal perimeter1.73.55.42.2-2.32.2-2.2-1.61.9-1.62.1-1.6-1.6-1.91.8-1.81.4
Epididymis fat weight0.72.53.61.5-1.31.4-1.7-1.81.7-1.81.5-1.9-1.9-1.21.4-1.41.3
Delta time in closed arm before/after self-admin0.40.30.6-0.50.6-0.60.70.8-0.80.8-0.10.60.60.4-0.50.5-0.0
Delta time in open arm before/after self-admin0.90.91.81.1-1.31.2-1.3-0.50.5-0.50.9-0.5-0.5-1.01.1-1.10.6
Diff in mean of infusions in LGA sessions0.00.10.2-0.10.1-0.1-0.4-0.20.2-0.2-0.4-0.3-0.3-0.1-0.00.00.4
Delay discount exponential model param1.71.93.21.3-1.51.5-1.8-1.41.3-1.41.3-1.3-1.3-1.21.5-1.51.1
Extinction: sum of active levers before priming0.10.10.30.3-0.30.3-0.2-0.30.3-0.30.2-0.2-0.2-0.4-0.00.00.5
Active lever presses in extinction session 60.60.60.90.7-0.70.7-0.0-1.01.0-1.00.6-0.9-0.9-0.70.6-0.60.8
Bone: final force0.71.12.71.6-1.01.0-0.9-1.01.0-1.00.8-0.9-0.9-1.20.9-0.91.4
Bone: final moment1.21.93.82.0-1.31.4-1.2-1.31.3-1.31.2-1.2-1.2-1.61.2-1.21.7
Food consumed during 24 hour testing period2.23.14.62.1-1.71.8-2.1-1.51.3-1.51.5-1.7-1.7-1.91.7-1.72.1
Glucose0.40.61.5-1.21.0-0.91.20.8-0.80.80.00.40.40.6-0.50.5-0.6
Heart weight8.413.116.13.3-3.63.6-3.7-4.03.6-3.93.4-3.7-3.7-3.73.4-3.43.6
Delay discount hyperbolic model param1.31.52.81.1-1.41.3-1.7-1.21.2-1.21.1-1.1-1.1-1.11.3-1.30.9
Intermittent access intake day 1-15 change0.40.91.9-0.90.9-0.90.71.0-1.01.0-0.30.90.91.2-0.80.8-1.4
Intermittent access intake escalation0.61.12.1-0.91.0-1.10.81.2-1.11.1-0.51.11.11.3-1.01.0-1.5
Intermittent access intake escalation 21.31.52.1-1.01.3-1.30.91.5-1.41.4-0.91.31.31.3-1.01.0-1.3
Intermitt. access day 1 inactive lever presses0.10.30.60.4-0.50.6-0.7-0.50.5-0.50.0-0.7-0.7-0.60.4-0.40.8
Intermitt. access day 15 inactive lever presses0.00.10.30.1-0.00.1-0.2-0.20.2-0.20.50.20.2-0.2-0.20.20.5
Intermitt. access escalation Index0.30.40.6-0.40.7-0.70.40.6-0.60.6-0.60.70.70.7-0.70.7-0.7
Intermittent access day 1 total infusions0.40.61.61.0-0.90.9-0.6-0.60.6-0.61.3-0.8-0.8-0.90.6-0.60.9
Intermittent access day 15 total infusions0.10.20.50.00.2-0.30.30.7-0.60.70.40.50.50.5-0.40.4-0.6
Intermittent access terminal intake (last 3 days)0.30.31.10.30.3-0.30.41.0-1.01.00.50.50.50.4-0.40.4-0.3
Intermittent access total infusions0.20.21.10.8-0.40.4-0.20.3-0.30.31.1-0.0-0.0-0.30.2-0.20.3
Intermittent access day 1 locomotion0.00.00.10.1-0.0-0.00.20.1-0.20.20.10.00.00.2-0.30.3-0.2
Intermittent access day 15 total locomotion0.10.10.60.7-0.60.5-0.4-0.10.1-0.10.8-0.2-0.2-0.20.3-0.30.0
Intermittent access total locomotion0.20.21.00.9-0.70.7-0.40.0-0.10.11.0-0.2-0.2-0.30.4-0.40.2
Intermittent access standard deviation0.00.10.70.5-0.20.2-0.30.2-0.10.10.8-0.1-0.1-0.00.1-0.10.1
Left kidney weight14.165.473.28.1-8.48.4-8.4-8.48.6-8.47.9-8.1-8.1-7.47.8-7.87.4
Right kidney weight15.671.277.98.6-8.78.7-8.6-8.78.8-8.88.3-8.3-8.3-7.98.2-8.28.1
Cocaine induced anxiety1.31.82.21.1-1.41.4-1.2-1.51.5-1.51.1-1.2-1.2-1.41.5-1.51.4
Post-drug Anxiety0.10.20.3-0.1-0.20.30.1-0.50.5-0.50.4-0.6-0.6-0.40.3-0.30.4
Baseline Anxiety2.22.63.4-1.81.7-1.71.81.5-1.51.5-1.31.11.11.7-1.81.8-1.7
Tail length0.10.41.0-0.80.7-0.70.50.3-0.20.3-0.30.30.30.9-0.90.9-1.0
Length with tail0.31.11.80.8-0.90.9-1.2-1.31.2-1.31.1-1.3-1.3-0.70.8-0.80.7
Length without tail0.82.73.41.7-1.51.5-1.7-1.71.6-1.71.2-1.8-1.8-1.51.6-1.61.8
Times rat made contact with spout1.82.02.61.5-1.41.4-1.4-1.41.0-1.31.1-1.6-1.6-1.61.5-1.51.6
Lifetime Intake0.40.42.11.1-0.70.7-0.6-0.20.2-0.21.5-0.3-0.3-0.60.5-0.50.6
Liver weight, left0.10.10.40.2-0.20.2-0.6-0.50.6-0.6-0.1-0.3-0.30.20.0-0.0-0.1
Liver weight, right0.40.71.40.6-0.70.7-0.7-1.11.2-1.10.6-1.0-1.0-0.60.6-0.60.5
Locomotor activity2.53.95.21.9-2.02.0-2.3-2.02.2-2.02.2-2.0-2.0-1.91.8-1.81.7
Locomotor testing distance0.10.10.3-0.10.3-0.3-0.10.4-0.40.50.00.60.60.2-0.50.5-0.2
Locomotor testing rearing0.20.50.90.9-0.80.7-0.9-0.60.8-0.60.7-0.4-0.4-0.70.7-0.70.6
Locomotion in novel chamber0.30.41.9-0.60.3-0.40.40.4-0.40.4-0.60.30.31.0-0.40.4-1.4
Locomotion in novel chamber post-restriction0.71.21.6-1.11.0-1.01.31.2-1.11.1-0.71.21.20.9-1.11.1-1.1
Fecal boli incidents, locomotor time 10.00.10.2-0.50.1-0.10.40.2-0.10.2-0.00.40.40.0-0.00.00.1
Change in fecal boli incidents, locomotor task0.80.71.10.7-0.90.9-1.0-1.01.0-1.00.3-1.0-1.0-0.80.8-0.80.5
Time >=10cm from walls, locomotor time 10.10.10.20.4-0.30.2-0.40.3-0.10.3-0.30.10.1-0.20.1-0.10.3
Bouts of movement, locomotor time 10.10.10.2-0.00.3-0.30.40.2-0.10.20.10.30.30.3-0.30.3-0.1
Total resting periods, locomotor time 10.20.20.4-0.20.6-0.50.60.4-0.40.40.00.50.50.4-0.50.5-0.2
Rest time, locomotor task time 10.10.10.30.4-0.20.2-0.5-0.10.1-0.10.4-0.1-0.1-0.10.3-0.30.2
Distance moved, locomotor task time 10.10.10.20.1-0.20.2-0.3-0.40.5-0.4-0.2-0.4-0.4-0.10.0-0.00.1
Vertical activity count, locomotor time 10.00.00.10.0-0.00.0-0.10.00.10.0-0.4-0.2-0.2-0.1-0.10.10.1
Time >=10cm from walls, locomotor time 20.30.50.7-0.60.6-0.60.50.8-0.70.8-0.80.70.70.8-0.70.7-0.8
Bouts of movement, locomotor time 20.20.41.0-0.70.8-0.81.00.5-0.40.5-0.50.40.40.6-0.70.7-0.5
Total resting periods, locomotor time 20.20.40.8-0.60.8-0.80.90.4-0.40.4-0.50.30.30.6-0.70.7-0.5
Rest time, locomotor task time 20.10.10.3-0.30.5-0.50.20.2-0.20.2-0.30.20.20.5-0.40.4-0.5
Distance moved, locomotor task time 20.60.81.20.9-1.01.0-1.1-0.80.8-0.80.5-1.0-1.0-0.80.8-0.80.7
Vertical activity count, locomotor time 20.30.40.90.5-0.90.9-0.9-0.60.6-0.60.1-0.7-0.7-0.60.5-0.50.5
Light reinforcement 10.30.61.20.7-1.11.0-1.1-0.90.8-0.81.1-0.5-0.5-0.50.6-0.60.4
Light reinforcement 20.50.71.60.5-1.01.0-1.3-1.11.1-1.01.1-0.7-0.7-0.30.7-0.70.1
Bone: marrow area2.35.07.32.7-2.72.6-2.6-1.61.8-1.62.3-1.8-1.8-2.62.2-2.22.3
Bone: maximum diameter5.09.311.13.3-3.33.3-3.1-2.83.2-2.83.0-3.0-3.0-3.13.0-3.02.7
Bone: maximum force1.83.25.62.4-1.81.8-1.6-1.71.6-1.81.5-1.7-1.7-2.01.6-1.62.0
Bone: maximum moment2.64.57.22.7-2.12.1-1.9-2.12.0-2.11.9-2.0-2.0-2.32.0-2.02.4
Mean time between licks in bursts0.51.12.4-1.11.1-1.21.60.9-1.00.9-0.41.21.20.8-0.90.9-1.1
Mean num. licks in bursts1.52.33.41.5-1.51.6-1.7-1.50.9-1.21.2-1.6-1.6-1.61.6-1.61.8
Cd content in liver1.11.21.61.2-1.21.1-1.3-1.11.0-1.20.8-1.0-1.0-1.21.1-1.11.1
Co content in liver0.30.30.80.7-0.60.6-0.9-0.70.8-0.80.5-0.3-0.3-0.30.4-0.40.3
Cu content in liver7.58.810.8-3.13.0-3.02.42.8-2.72.7-2.93.13.13.3-3.23.2-3.3
Fe content in liver1.92.32.71.5-1.51.5-1.0-1.61.5-1.61.4-1.6-1.6-1.61.5-1.51.5
K content in liver1.51.42.9-1.01.1-1.20.60.9-0.70.9-1.31.31.31.7-1.41.4-1.3
Mg content in liver1.91.93.2-1.31.4-1.41.01.2-0.91.2-1.31.51.51.8-1.61.6-1.4
Mn content in liver0.10.10.30.3-0.0-0.0-0.2-0.20.2-0.1-0.30.20.20.5-0.30.3-0.4
Na content in liver1.41.52.2-0.91.4-1.41.51.4-1.31.4-1.01.11.11.2-1.21.2-1.2
Rb content in liver0.20.20.50.5-0.30.3-0.1-0.50.7-0.50.3-0.4-0.4-0.40.4-0.40.5
Se content in liver1.01.21.7-1.21.0-1.00.60.8-1.00.9-1.21.21.21.3-1.21.2-1.2
Sr content in liver2.21.92.6-1.61.4-1.40.91.6-1.51.6-1.21.21.21.4-1.31.3-1.3
Zn content in liver0.10.10.5-0.4-0.00.0-0.70.1-0.10.0-0.00.30.30.4-0.10.1-0.2
Bone: minimum diameter0.40.71.20.9-1.11.0-1.0-0.91.0-0.80.8-0.5-0.5-0.70.8-0.80.3
Time in familiar zone, hab. session 10.30.30.70.9-0.60.6-0.7-0.40.4-0.30.3-0.4-0.4-0.50.4-0.40.5
Time in novel zone, hab. session 10.90.91.50.5-0.80.7-0.3-1.21.0-1.21.2-1.0-1.0-0.91.1-1.10.6
Total zone transitions, hab. session 11.92.73.3-1.61.7-1.71.51.6-1.51.5-1.81.71.71.6-1.71.7-1.5
Total locomotion distance, hab. session 10.40.61.1-0.80.6-0.60.30.7-0.70.6-0.80.80.81.1-0.80.8-1.0
Locomotion velocity, hab. session 10.60.91.5-0.90.8-0.80.31.0-0.90.9-1.01.01.01.2-1.01.0-1.1
Time in familiar zone, hab. session 20.10.10.4-0.50.2-0.30.30.00.10.1-0.10.30.30.6-0.30.3-0.6
Time in novel zone, hab. session 20.70.71.20.9-0.80.8-0.7-0.70.5-0.70.8-1.0-1.0-1.11.0-1.01.0
Total zone transitions, hab. session 20.00.00.30.10.1-0.1-0.10.5-0.10.4-0.20.20.20.1-0.00.00.2
Total locomotion distance, hab. session 20.10.10.2-0.20.2-0.2-0.10.4-0.30.4-0.30.40.40.5-0.30.3-0.4
Locomotion velocity, hab. session 20.30.40.6-0.50.5-0.50.10.7-0.60.8-0.70.70.70.8-0.60.6-0.6
Novel to familiar place preference ratio2.62.94.81.5-1.61.6-1.4-2.21.9-2.01.6-1.7-1.7-1.61.6-1.61.4
Novelty place preference3.53.86.01.8-1.91.9-1.6-2.52.2-2.31.8-2.0-2.0-1.81.8-1.81.6
Time in novel zone, NPP test4.85.27.72.1-2.22.2-1.9-2.82.5-2.62.1-2.4-2.4-2.22.2-2.21.9
Total zone transitions, NPP test0.50.81.4-0.30.8-0.80.51.2-1.01.1-1.01.11.10.6-0.90.9-0.4
Total locomotion distance, NPP test0.20.30.7-0.20.3-0.3-0.10.7-0.80.8-0.50.70.70.6-0.50.5-0.5
Locomotion velocity, NPP test1.11.62.4-0.81.0-1.00.61.5-1.61.5-1.31.51.51.3-1.31.3-1.2
Intraocular pressure0.30.50.70.7-0.70.7-0.3-0.50.5-0.50.5-0.9-0.9-0.90.7-0.70.6
Delta distance traveled before/after self-admin1.61.72.51.2-1.41.4-1.6-1.41.4-1.41.0-1.5-1.5-1.01.3-1.30.9
Delta ambulatory time before/after self-admin2.12.63.61.5-1.61.6-1.7-1.91.9-1.91.0-1.9-1.9-1.31.5-1.51.2
Parametrial fat weight0.71.62.7-1.61.3-1.30.91.2-1.21.2-1.50.70.71.5-1.31.3-1.6
Pavlov. Cond. lever latency2.32.94.31.8-1.71.7-1.4-1.81.5-1.62.1-1.7-1.7-1.81.8-1.81.7
Pavlov. Cond. magazine entry latency2.53.25.4-2.02.0-2.01.81.7-1.61.7-2.31.51.51.8-1.71.7-1.6
Pavlov. Cond. change in total contacts3.13.35.6-2.12.0-2.01.91.8-1.61.7-2.41.51.51.8-1.71.7-1.6
Pavlov. Cond. index score2.32.94.3-2.01.9-1.91.81.7-1.51.6-2.11.41.41.7-1.61.6-1.5
Pavlov. Cond. latency score1.92.44.0-1.71.7-1.71.51.6-1.31.4-2.01.41.41.6-1.51.5-1.4
Pavlov. Cond. lever contacts4.55.47.1-2.42.4-2.42.12.4-2.12.3-2.72.22.22.4-2.32.3-2.3
Pavlov. Cond. magazine entry number3.03.86.02.3-2.22.2-2.1-1.91.8-1.82.5-1.6-1.6-1.81.8-1.81.7
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.50.6-0.60.61.0-1.10.9-0.60.80.80.6-0.60.6-0.5
Pavlov. Cond. lever-magazine prob. diff.2.93.55.0-2.22.1-2.02.01.9-1.71.8-2.21.61.61.9-1.81.8-1.7
Pavlov. Cond. response bias4.65.77.9-2.72.6-2.62.42.4-2.22.3-2.82.02.02.4-2.32.3-2.3
Pavlov. Cond. lever latency0.20.20.50.5-0.50.5-0.6-0.40.2-0.40.2-0.5-0.5-0.70.4-0.40.4
Pavlov. Cond. magazine entry latency2.73.24.0-1.71.8-1.81.91.9-2.02.0-1.31.91.91.8-1.71.7-1.4
Pavlov. Cond. change in total contacts0.10.20.3-0.20.5-0.40.50.3-0.10.3-0.10.50.50.6-0.50.5-0.1
Pavlov. Cond. index score1.21.62.1-1.21.3-1.31.41.2-1.21.3-0.81.41.41.5-1.21.2-1.1
Pavlov. Cond. latency score1.51.92.5-1.41.4-1.41.41.4-1.31.4-1.01.51.51.6-1.41.4-1.2
Pavlov. Cond. lever contacts0.30.40.7-0.60.6-0.60.80.5-0.40.6-0.30.60.60.8-0.60.6-0.5
Pavlov. Cond. magazine entry number1.92.32.71.5-1.51.5-1.5-1.61.6-1.61.2-1.6-1.6-1.71.6-1.61.2
Pavlov. Cond. intertrial magazine entries2.33.44.31.6-1.71.7-1.5-2.12.0-2.11.6-2.0-2.0-2.01.9-1.91.9
Pavlov. Cond. lever-magazine prob. diff.1.31.82.4-1.31.4-1.31.41.3-1.21.3-0.91.51.51.6-1.31.3-1.2
Pavlov. Cond. response bias0.60.81.5-1.01.0-1.01.20.8-0.70.9-0.50.90.91.1-0.80.8-0.7
Time in closed arm before self-admin3.03.84.5-1.52.0-2.01.81.8-1.81.8-2.12.12.12.0-2.02.0-2.1
Time in closed arm after self-admin1.61.72.6-1.01.4-1.41.31.0-1.01.0-1.41.31.31.5-1.61.6-1.5
Time in open arm before self-admin0.10.10.4-0.60.3-0.30.50.5-0.50.5-0.10.00.00.2-0.40.4-0.1
Time in open arm after self-admin0.60.71.70.8-1.11.1-0.9-0.30.3-0.31.3-0.5-0.5-0.91.0-1.00.7
Bone: periosteal estimation2.14.46.72.6-2.42.4-2.2-1.82.1-1.82.1-1.8-1.8-2.22.0-2.01.9
Bone: periosteal perimeter2.95.06.32.4-2.52.4-2.1-2.22.5-2.22.4-2.1-2.1-2.22.2-2.21.6
Bone: post-yield work0.50.72.20.9-0.70.7-0.5-0.70.5-0.70.7-0.8-0.8-1.30.8-0.81.5
Progressive ratio test 1 active lever presses0.10.10.50.4-0.20.2-0.1-0.20.1-0.10.7-0.2-0.2-0.30.2-0.20.2
Progressive ratio test 1 breakpoint0.00.00.30.2-0.00.00.0-0.0-0.10.10.5-0.0-0.0-0.1-0.00.00.1
Progressive ratio test 1 inactive lever presses0.20.31.00.7-0.60.6-0.6-0.30.3-0.31.0-0.4-0.4-0.60.4-0.40.6
Progressive ratio test 2 active lever presses0.40.51.81.3-0.60.7-0.7-0.00.0-0.01.1-0.6-0.6-0.70.6-0.60.9
Progressive ratio test 2 breakpoint0.30.41.51.2-0.60.6-0.60.1-0.10.11.0-0.4-0.4-0.60.5-0.50.8
Progressive ratio test 2 inactive lever presses0.10.20.50.20.3-0.30.00.7-0.70.7-0.10.30.30.3-0.50.5-0.1
Incentive Sensitization - Responses0.60.82.51.6-0.90.9-0.8-0.10.2-0.21.4-0.7-0.7-1.00.8-0.81.3
Incentive Sensitization - Breakpoint0.70.92.61.6-0.90.9-0.9-0.10.2-0.21.4-0.7-0.7-1.00.9-0.91.3
Sum of active levers in priming session hrs 5-60.10.10.10.4-0.30.3-0.3-0.10.1-0.1-0.40.00.0-0.20.2-0.20.2
Progressive ratio0.20.30.9-0.40.7-0.60.90.4-0.50.4-0.70.20.20.3-0.50.5-0.2
Food seeking constrained by brief footshock0.60.71.50.7-0.80.8-1.2-1.11.1-1.10.2-0.9-0.9-0.50.7-0.70.6
Seeking ratio, punishment vs. effort0.30.41.30.5-0.70.7-1.1-0.70.7-0.70.5-0.5-0.5-0.40.6-0.60.5
Retroperitoneal fat weight1.77.210.12.4-2.52.5-3.1-2.93.1-2.92.0-3.2-3.2-2.12.4-2.42.3
Reaction time number correct0.91.82.3-1.31.4-1.41.11.3-1.11.3-1.21.41.41.4-1.51.5-1.5
Reaction time mean minus median0.20.40.80.6-0.50.5-0.1-0.80.6-0.90.7-0.7-0.7-0.70.5-0.50.6
Reaction time mean minus median AUC0.41.11.71.3-1.01.0-0.7-1.10.8-1.21.3-1.0-1.0-1.21.1-1.11.0
Reaction time num false alarms0.00.10.40.6-0.20.2-0.0-0.30.2-0.4-0.0-0.1-0.1-0.4-0.10.10.1
Reaction time num false alarms AUC0.10.10.40.7-0.20.2-0.2-0.40.2-0.40.1-0.1-0.1-0.4-0.00.00.2
Reaction time trials correct on left0.91.82.3-1.31.4-1.41.11.3-1.11.3-1.21.41.41.4-1.51.5-1.5
Reaction time trials on left1.01.92.4-1.31.4-1.41.21.3-1.11.3-1.21.41.41.5-1.61.6-1.5
Reaction time mean0.10.10.7-0.40.4-0.40.8-0.10.0-0.20.00.20.20.2-0.20.2-0.2
Reaction time mean AUC0.10.10.6-0.40.4-0.40.8-0.10.1-0.20.00.30.30.2-0.20.2-0.2
Median of all reaction times0.20.31.1-0.70.7-0.61.10.2-0.20.1-0.20.50.50.5-0.40.4-0.4
Reaction time omissions0.10.10.3-0.30.4-0.30.60.0-0.2-0.0-0.10.40.40.0-0.20.2-0.0
Reaction time false alarm rate0.40.61.21.1-0.80.8-0.6-0.90.6-0.90.5-0.7-0.7-1.00.6-0.60.8
Reaction time premature initiation rate0.10.10.30.50.1-0.0-0.40.2-0.20.4-0.30.10.1-0.0-0.10.10.5
Reaction time premature initiations0.20.30.70.00.6-0.60.20.7-0.60.9-0.60.60.60.6-0.70.7-0.2
Std. dev. reaction times0.20.31.10.3-0.30.30.1-0.90.8-1.00.5-0.4-0.4-0.30.4-0.40.3
Reaction time trials completed1.01.92.4-1.31.4-1.41.21.3-1.11.3-1.21.41.41.5-1.61.6-1.5
Reaction time trials AUC0.81.51.9-1.11.2-1.21.01.1-0.91.1-1.01.31.31.3-1.41.4-1.4
Run reversals in cocaine runway, females2.12.14.5-1.81.4-1.41.91.1-1.11.1-1.50.90.91.9-1.31.3-2.1
Run reversals in cocaine runway, males1.81.92.21.4-1.41.4-1.3-1.51.3-1.30.9-1.5-1.5-1.41.5-1.51.1
Latency to leave start box in cocaine runway0.50.51.50.7-0.90.9-0.6-0.30.3-0.21.2-0.6-0.6-0.90.8-0.80.9
Latency to leave start box in cocaine runway, F0.20.20.60.4-0.40.5-0.50.3-0.20.30.7-0.1-0.1-0.60.5-0.50.8
Latency to leave start box in cocaine runway, M0.80.71.30.8-1.00.9-0.6-0.90.8-0.81.2-0.9-0.9-0.70.8-0.80.6
Std. dev. time between licks in bursts0.81.11.8-1.01.2-1.11.40.9-0.70.8-0.91.21.21.1-1.01.0-1.0
Total sessions with >9 infusions2.73.36.72.1-1.81.8-1.7-1.81.7-1.72.6-1.5-1.5-1.71.8-1.81.7
Short access day 1 total inactive lever presses3.24.36.12.3-2.12.1-2.5-2.12.0-2.02.2-1.8-1.8-2.11.8-1.82.3
Short access day 10 total inactive lever presses0.92.23.31.2-1.61.6-1.8-1.61.7-1.71.3-1.5-1.5-1.41.2-1.21.4
Short access day 1 total infusions1.82.33.91.7-1.41.4-1.6-1.61.5-1.52.0-1.6-1.6-1.31.3-1.31.4
Short access day 10 total infusions0.10.10.40.4-0.20.1-0.2-0.20.2-0.20.6-0.2-0.2-0.1-0.30.30.1
Short access total infusions1.72.14.21.7-1.51.4-1.5-1.41.4-1.42.1-1.3-1.3-1.41.3-1.31.4
Short access day 1 locomotion0.20.30.90.7-0.60.6-0.5-0.30.2-0.21.0-0.2-0.2-0.50.6-0.60.5
Short access day 10 total locomotion0.51.01.5-0.70.9-0.90.81.2-1.21.2-0.61.21.20.8-0.90.9-0.9
Short access total locomotion0.00.00.20.1-0.0-0.00.1-0.0-0.00.00.50.30.30.1-0.20.2-0.2
One hour access (0.3 mA shock)0.40.41.10.20.3-0.30.21.0-1.01.00.10.80.80.4-0.60.6-0.3
Compulsive drug intake0.10.20.90.2-0.10.2-0.4-0.10.1-0.1-0.8-0.1-0.1-0.60.1-0.11.0
One hour access (shock baseline)0.30.41.10.10.2-0.30.41.0-1.01.00.50.70.70.5-0.50.5-0.8
Social response proportion0.20.31.30.1-0.40.4-0.3-0.2-0.0-0.31.2-0.6-0.6-0.30.7-0.70.2
Social responses0.20.30.7-0.70.5-0.50.40.4-0.40.3-0.60.40.40.8-0.40.4-0.7
Social time2.53.56.1-2.02.1-2.12.51.9-1.91.8-1.12.02.01.8-1.41.4-1.7
Soleus weight0.20.71.61.0-0.80.8-1.2-0.40.2-0.40.3-0.9-0.9-1.10.9-0.91.3
Bone: stiffness0.60.91.71.3-0.80.8-0.7-1.00.9-1.10.6-0.8-0.8-1.20.8-0.81.2
Tibialis anterior weight0.30.92.1-0.70.8-0.90.51.0-1.51.0-0.91.01.01.0-1.01.0-0.9
Time to tail flick, vehicle, before self-admin0.30.30.40.6-0.50.5-0.6-0.70.6-0.70.3-0.5-0.5-0.50.6-0.60.5
Time to tail flick, vehicle, after self-admin0.10.10.2-0.20.2-0.20.20.4-0.40.4-0.30.40.40.1-0.00.0-0.3
Time to tail flick, test, before self-admin0.20.20.40.1-0.30.3-0.0-0.70.7-0.7-0.1-0.5-0.5-0.20.4-0.40.1
Time to tail flick, test, after self-admin1.01.01.8-0.80.9-0.90.81.3-1.31.3-1.11.21.20.7-0.60.6-0.7
Delta time to tail flick, vehicle, before/after SA0.50.51.00.8-0.70.8-0.5-0.40.4-0.40.8-0.5-0.5-0.90.7-0.71.0
Delta time to tail flick, test, before/after SA1.71.73.4-0.71.1-1.10.61.9-1.91.9-1.11.61.60.9-1.11.1-0.8
Tibia length0.72.02.71.6-1.41.4-1.5-1.41.4-1.50.9-1.4-1.4-1.51.3-1.31.4
Ambulatory time before self-admin0.10.10.2-0.40.3-0.30.40.3-0.30.30.30.30.30.20.0-0.0-0.2
Ambulatory time after self-admin0.00.00.1-0.20.1-0.1-0.1-0.10.1-0.1-0.3-0.1-0.10.20.2-0.2-0.2
Bone: tissue strength0.40.41.01.0-0.60.6-0.6-0.50.3-0.50.8-0.5-0.5-0.80.6-0.60.9
Total heroin consumption0.91.11.51.0-1.01.0-1.1-1.11.1-1.10.2-1.2-1.2-1.10.9-0.91.2
Bone: trabecular number0.20.40.8-0.70.6-0.60.80.8-0.90.8-0.40.50.50.4-0.50.5-0.6
Bone: trabecular spacing1.01.31.61.2-1.21.2-1.2-1.21.2-1.31.2-1.0-1.0-1.01.1-1.11.1
Bone: trabecular thickness0.60.71.6-0.90.9-0.91.00.6-0.50.6-0.50.70.71.3-0.80.8-1.1
Bone: trabecular tissue density1.01.52.0-1.01.3-1.31.21.1-1.31.1-1.01.31.31.2-1.41.4-1.0
Water consumed over 24 hours3.64.96.62.3-2.22.2-2.6-2.01.7-2.01.7-2.4-2.4-2.32.3-2.32.3
Number of responses in last shaping day0.60.71.0-0.91.0-1.00.70.8-0.90.9-0.90.70.70.9-0.80.8-0.8