Mog

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IC	gene expression	Mog	0.25	0.16	1.7e-04	0.13	0.08	0.06	0.12	4.2e-06	2.4e-04	1.7e-03	6.6e-06
2	pVTA	gene expression	Mog	0.4	0.17	2.3e-14	0.23	0.19	0.19	0.21	3.9e-18	1.7e-15	4.9e-15	6.6e-17
3	NAcc	gene expression	Mog	0.35	0.09	0.0e+00	0.17	0.17	0.17	0.17	1.9e-25	2.0e-24	1.5e-25	2.1e-25
4	Brain	gene expression	Mog	0.47	0.13	0.0e+00	0.31	0.33	0.34	0.34	4.4e-29	1.7e-31	1.7e-32	2.5e-32
5	BLA	gene expression	Mog	0.32	0.11	3.1e-11	0.16	0.18	0.19	0.19	1.0e-08	4.2e-10	2.8e-10	1.9e-10
6	LHb	gene expression	Mog	0.25	0.15	5.2e-03	0	0.06	0.05	0.06	3.3e-01	1.6e-02	2.6e-02	1.8e-02
7	RMTg	mRNA stability	Mog	0.2	0.13	4.4e-03	0.05	0.05	0.02	0.04	2.2e-02	1.8e-02	1.1e-01	2.8e-02
8	RMTg	isoform ratio	NM_022668.2	0.24	0.14	7.6e-03	0	0.01	0.05	-0	2.4e-01	2.0e-01	2.4e-02	4.3e-01
9	Brain	intron excision ratio	chr20_1518653_1520418	0.09	0.06	1.1e-05	0.03	0.03	0.03	0.03	1.1e-03	9.6e-04	4.9e-04	1.1e-03
10	NAcc	intron excision ratio	chr20_1518653_1520418	0.02	0.01	6.3e-04	0.02	0.01	0.01	0.01	1.0e-03	2.2e-03	1.3e-02	3.6e-03
11	pVTA	intron excision ratio	chr20_1518653_1520418	0.05	0.04	3.8e-04	0.05	0.04	0.04	0.05	4.9e-05	1.6e-04	5.2e-04	5.5e-05
12	pVTA	intron excision ratio	chr20_1520003_1520418	0.05	0.04	4.4e-04	0.05	0.04	0.03	0.05	5.5e-05	2.4e-04	1.5e-03	9.6e-05
13	NAcc	intron excision ratio	chr20_1520003_1520418	0.03	0.02	7.7e-05	0.02	0.02	0.02	0.02	3.1e-04	3.2e-04	7.0e-04	2.3e-04
14	Brain	intron excision ratio	chr20_1520003_1520418	0.09	0.05	2.0e-05	0.03	0.03	0.03	0.03	8.7e-04	8.4e-04	6.1e-04	1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bone: apparent density	1.2	2.0	3.9	-1.6	-1.5	-1.3	-1.0	-1.4	-1.4	-2.0	-0.6	1.1	1.4	1.7	-1.6	-1.4	-1.2
Area under the delay curve	1.5	1.8	4.2	0.1	-0.1	0.1	-0.5	0.6	0.7	0.7	-1.7	-2.0	-1.8	-1.5	1.7	1.8	2.0
BMI with tail	0.7	2.5	5.0	-1.3	-1.4	-1.3	-1.8	-1.5	-1.1	-0.3	-1.5	-1.6	-1.8	-2.2	1.5	2.1	1.8
BMI without tail	1.3	4.1	8.6	-0.5	-0.7	-0.6	-1.4	-0.4	0.2	0.7	-2.4	-2.8	-2.7	-2.9	2.7	2.9	2.9
Body weight	3.4	15.0	30.4	2.9	2.4	2.5	1.0	2.8	3.5	3.9	-2.4	-4.6	-5.4	-5.5	5.0	4.9	4.3
Weight adjusted by age	1.9	2.8	6.9	1.3	1.6	1.4	0.7	2.0	2.0	1.7	-1.2	-1.7	-1.6	-2.6	1.8	1.6	1.4
Bone surface	0.3	0.5	1.8	0.7	0.8	1.0	0.9	1.2	1.3	0.7	-0.7	-0.4	-0.4	-0.2	0.4	0.2	0.1
Bone volume	0.1	0.2	1.6	-0.3	-0.2	-0.1	-0.2	0.2	0.4	-0.2	-1.3	-0.4	-0.2	-0.0	0.1	0.1	0.1
Breakpoint value in progressive ratio session	0.7	0.8	3.1	-0.4	-0.4	-0.4	0.2	-0.9	-1.1	-0.4	1.7	1.3	1.0	0.5	-1.0	-0.8	-1.0
Number of licking bursts	0.5	0.7	2.0	1.4	1.1	1.1	1.1	1.1	1.0	1.2	1.0	0.1	-0.2	-0.0	0.3	0.1	-0.0
Context. condit. distance diff. score	3.5	4.2	8.2	1.3	1.5	1.4	2.1	1.2	0.8	0.3	2.6	2.8	2.3	2.4	-2.3	-2.9	-2.8
Locomotion velocity, session 1	0.3	0.4	1.0	0.6	0.5	0.7	1.0	0.6	0.7	0.6	0.8	0.5	0.2	0.3	-0.0	-0.4	-0.7
Locomotion distance, session 1	1.1	1.3	2.5	-1.3	-1.4	-1.3	-1.0	-1.6	-1.4	-1.4	0.2	0.9	1.1	1.1	-1.0	-0.9	-0.8
Locomotion velocity, session 2	0.3	0.3	1.6	0.6	0.5	0.5	0.9	0.1	0.3	0.9	1.3	0.4	-0.3	-0.2	0.6	0.2	-0.2
Locomotion distance, session 2	0.5	0.7	1.3	-0.6	-0.5	-0.4	-0.0	-0.7	-0.7	-0.8	0.5	1.1	1.1	1.0	-1.0	-1.1	-1.2
Locomotion velocity, session 3	0.4	0.4	1.2	-1.0	-0.8	-0.9	-0.9	-1.1	-1.0	-0.4	0.2	0.0	-0.0	0.1	0.1	0.3	0.2
Locomotion distance, session 3	1.0	1.1	2.2	-0.6	-0.6	-0.7	-0.2	-0.8	-1.0	-1.0	0.8	1.3	1.5	1.4	-1.5	-1.4	-1.2
Stereotopy head waving bouts, day 3	1.5	1.7	3.5	1.7	1.6	1.6	1.4	1.5	1.6	1.9	0.7	-0.5	-1.3	-1.0	1.0	0.8	0.7
Stereotopy head waving duration, day 3	1.0	1.2	2.1	1.3	1.2	1.2	0.9	1.1	1.3	1.5	0.2	-0.7	-1.2	-1.0	1.1	0.9	0.8
Locomotion velocity, session 7	1.6	1.8	4.4	-0.2	-0.5	-0.5	0.0	-0.4	-0.5	-1.0	0.7	1.8	2.1	2.1	-1.6	-2.0	-1.9
Locomotion distance, session 7	1.8	2.3	4.6	-1.0	-1.1	-1.3	-0.8	-1.1	-1.3	-1.8	0.1	1.6	2.1	2.0	-2.0	-1.9	-1.7
Stereotopy head waving bouts, day 7	1.7	1.9	3.7	0.9	0.7	0.7	0.2	1.1	1.4	1.4	-1.1	-1.7	-1.8	-1.5	1.9	1.7	1.8
Stereotopy head waving duration, day 7	1.7	2.0	4.0	0.8	0.8	0.9	0.3	1.2	1.5	1.5	-1.0	-1.8	-1.8	-1.6	2.0	1.8	1.9
Locomotion velocity, session 8	3.2	3.9	8.0	2.8	2.7	2.7	2.8	2.6	2.7	2.5	1.6	0.5	-0.4	-0.4	0.5	-0.3	-0.4
Locomotion distance, session 8	2.1	3.0	6.8	0.7	1.1	1.0	1.6	0.7	0.4	-0.1	2.0	2.4	2.2	1.9	-2.2	-2.6	-2.5
Degree of sensitization distance	0.3	0.3	0.9	0.7	0.8	0.7	0.5	0.9	0.9	0.5	-0.1	0.0	-0.0	0.1	0.0	-0.2	-0.2
Degree of sensitization stereotypy	0.6	0.7	1.7	0.2	0.1	0.2	-0.2	0.5	0.7	0.7	-0.9	-1.1	-1.0	-0.8	1.3	1.1	1.2
Conditioned locomotion	1.4	1.6	3.8	0.7	0.7	0.7	0.3	0.8	0.9	1.5	-0.3	-1.4	-1.7	-1.7	1.9	1.7	1.6
Cocaine response after cond. corrected	0.2	0.3	0.7	-0.6	-0.5	-0.5	-0.2	-0.9	-0.7	-0.2	0.8	0.6	0.6	0.6	0.0	-0.2	-0.3
Cocaine response after cond. not corrected	0.5	0.6	1.5	0.8	0.9	0.9	0.8	0.8	0.9	1.2	0.5	-0.3	-0.7	-0.5	1.1	0.6	0.5
Cocaine response before conditioning	4.9	5.9	9.7	2.1	2.3	2.2	1.3	3.0	3.1	2.6	-1.5	-2.5	-2.8	-2.7	2.6	2.3	2.2
Saline control response	1.3	1.7	4.1	-1.1	-1.1	-1.0	-1.6	-0.5	-0.3	-0.4	-2.0	-1.8	-1.2	-1.3	1.2	1.5	1.7
Bone: connectivity density	1.3	2.0	5.0	-1.0	-0.8	-0.6	-0.0	-0.7	-0.9	-1.5	0.1	1.7	1.8	2.2	-2.0	-2.0	-1.8
Bone: cortical apparent density	0.9	1.3	3.0	-1.3	-1.4	-1.4	-1.7	-1.2	-1.1	-0.9	-1.2	-1.0	-0.5	-0.7	0.4	1.0	1.2
Bone: cortical area	0.7	1.0	2.3	1.1	0.8	0.9	0.4	1.1	1.2	0.8	-0.9	-1.2	-1.0	-1.5	1.0	1.0	0.9
Bone: cortical porosity	0.1	0.1	0.4	-0.1	0.0	0.0	-0.2	0.2	0.1	-0.0	-0.6	-0.5	-0.4	-0.3	0.3	0.4	0.6
Bone: cortical porosity	0.3	0.4	1.0	0.7	0.7	0.7	0.4	1.0	0.8	0.5	-0.4	-0.6	-0.5	-0.5	0.4	0.4	0.5
Bone: cortical thickness	1.4	2.3	4.5	-1.3	-1.5	-1.4	-2.0	-1.3	-1.0	-1.0	-2.1	-1.8	-1.1	-1.6	1.0	1.7	1.7
Bone: cortical thickness	2.1	2.5	6.0	-2.2	-2.0	-2.1	-2.5	-1.9	-1.9	-1.6	-1.5	-0.8	-0.2	-0.6	-0.0	0.8	1.1
Bone: cortical tissue density	0.8	1.1	2.5	-1.2	-1.3	-1.2	-1.6	-1.1	-1.0	-0.8	-1.1	-0.9	-0.5	-0.6	0.4	0.9	1.1
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	-0.1	-0.0	0.0	0.2	-0.1	-0.1	-0.1	0.3	0.3	0.4	0.4	-0.2	-0.3	-0.3
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.6	-0.5	-0.5	-0.4	-0.5	-0.6	-0.4	-0.0	-0.3	-0.6	-0.7	-0.5	0.7	0.8	0.8
Condit. Reinf. active responses	0.4	0.5	1.4	-0.3	-0.3	-0.4	-0.2	-0.6	-0.7	-0.7	0.7	0.8	1.2	0.8	-0.9	-0.9	-0.9
Condit. Reinf. inactive responses	2.0	2.5	5.3	-1.0	-1.2	-1.3	-0.9	-1.5	-1.7	-1.9	0.6	1.6	2.3	1.6	-2.0	-1.8	-1.7
Incentive salience index mean	0.8	1.0	2.9	1.0	0.9	0.9	1.3	0.5	0.4	0.6	1.7	1.2	0.9	0.8	-0.6	-1.1	-1.2
Condit. Reinf. lever presses	2.7	3.8	11.1	1.6	1.5	1.5	2.3	0.7	0.4	0.7	3.3	2.7	2.0	1.6	-1.7	-2.3	-2.6
Condit. Reinf. active minus inactive responses	0.6	0.8	1.5	0.8	0.8	0.8	0.4	1.1	1.2	1.0	-0.4	-1.1	-0.8	-1.0	1.1	0.9	0.8
Condit. Reinf. active-inactive response ratio	1.7	1.9	3.0	1.3	1.3	1.3	0.8	1.5	1.7	1.7	-0.2	-1.3	-1.5	-1.5	1.7	1.4	1.3
Condit. Reinf. active responses	0.1	0.1	0.3	0.3	0.3	0.3	0.3	0.4	0.4	-0.0	0.2	0.2	0.6	0.3	-0.4	-0.4	-0.5
Condit. Reinf. inactive responses	0.7	0.9	2.4	-0.5	-0.5	-0.5	-0.1	-0.6	-0.8	-1.0	0.5	1.1	1.4	1.2	-1.6	-1.3	-1.3
Condit. Reinf. lever presses	0.8	1.2	3.1	0.3	0.0	0.0	0.3	0.2	-0.1	-0.8	0.8	1.1	1.8	1.4	-1.7	-1.7	-1.6
Condit. Reinf. lever reinforcers received	0.2	0.3	0.5	0.4	0.4	0.4	0.5	0.5	0.4	-0.0	0.5	0.4	0.7	0.6	-0.7	-0.7	-0.7
Conditioned reinforcement - actives	1.0	1.7	5.7	-1.4	-1.1	-1.2	-1.6	0.0	-0.2	-0.4	-2.4	-1.9	-1.1	-1.3	1.0	1.2	1.7
Conditioned reinforcement - inactives	0.7	1.0	2.4	-0.8	-0.9	-0.9	-1.2	-0.4	-0.5	-0.8	-1.5	-1.4	-0.6	-1.4	0.5	0.8	1.0
Conditioned locomotion	0.3	0.4	1.3	-0.0	0.1	0.1	-0.2	0.7	0.5	0.3	-1.1	-1.1	-0.7	-0.6	0.6	0.7	1.0
Patch foraging indifference point 0 sec	0.9	1.7	5.2	-1.9	-1.7	-1.7	-2.0	-0.9	-0.7	-1.5	-2.3	-0.8	0.0	0.4	-0.4	-0.0	0.5
Patch foraging indifference point AUC	0.8	1.1	2.5	0.8	0.7	0.6	-0.0	0.9	1.0	0.8	-1.0	-1.6	-1.2	-1.6	1.1	1.4	1.2
Delay disc. indifference point, 0s delay	0.7	0.8	1.7	0.9	0.7	0.8	0.6	0.8	1.0	1.3	0.2	-0.7	-0.9	-0.6	1.3	1.0	1.0
Delay disc. indifference point, 16s delay	2.3	2.5	6.1	-1.7	-2.0	-1.8	-2.1	-1.1	-0.9	-1.0	-2.5	-1.8	-1.1	-1.1	0.9	1.4	1.7
Delay disc. indifference point, 2s delay	1.6	1.8	3.3	1.0	0.9	0.8	0.3	1.1	1.2	1.5	-0.5	-1.6	-1.7	-1.6	1.8	1.7	1.7
Delay disc. indifference point, 24s delay	0.8	0.9	3.6	-0.6	-0.7	-0.6	-0.9	-0.0	0.2	-0.1	-1.9	-1.4	-0.9	-0.8	1.1	1.1	1.3
Delay disc. indifference point, 4s delay	2.7	2.9	5.2	1.0	0.9	1.1	0.4	1.5	1.6	1.8	-1.0	-2.1	-2.2	-2.1	2.3	2.2	2.2
Delay disc. indifference point, 8s delay	0.5	0.6	2.5	-0.2	-0.1	-0.1	-0.5	0.4	0.3	-0.0	-1.6	-1.3	-0.8	-0.7	0.4	0.8	1.1
Indifference point function ln k	0.3	0.5	1.1	0.7	0.6	0.6	1.0	0.7	0.6	0.3	1.0	0.8	0.6	0.2	-0.6	-0.9	-0.8
Indifference point function log k	0.3	0.5	1.1	0.7	0.6	0.6	1.0	0.7	0.6	0.3	1.0	0.8	0.6	0.2	-0.6	-0.9	-0.8
Patch foraging total patch changes 0 sec	1.1	2.0	6.7	-2.0	-1.8	-1.8	-2.2	-1.0	-0.7	-1.6	-2.6	-1.0	-0.1	0.3	-0.3	0.2	0.7
Patch foraging total patch changes 12 sec	1.2	1.6	4.6	-1.7	-1.6	-1.6	-2.0	-1.0	-0.8	-1.5	-2.2	-1.1	-0.1	-0.2	-0.1	0.5	0.7
Patch foraging total patch changes 18 sec	1.9	2.9	5.8	-2.3	-2.3	-2.3	-2.4	-2.1	-2.0	-2.3	-1.7	0.0	0.5	0.9	-1.2	-0.3	-0.0
Patch foraging total patch changes 24 sec	2.3	3.9	8.0	-2.8	-2.8	-2.7	-2.7	-2.1	-2.0	-2.8	-2.4	-0.4	0.7	0.9	-0.8	-0.2	-0.0
Patch foraging total patch changes 6 sec	2.0	3.0	9.0	-2.3	-2.2	-2.1	-2.6	-1.4	-1.0	-1.6	-3.0	-1.6	-0.8	-0.3	0.4	1.0	1.4
Patch foraging time to switch 0 sec	0.6	1.3	3.6	-1.7	-1.6	-1.6	-1.1	-1.9	-1.8	-1.0	-0.1	0.7	-0.0	0.6	-0.2	0.0	-0.0
Patch foraging water rate 0 sec	0.2	0.5	2.7	-0.2	-0.1	-0.2	-0.7	0.7	0.8	-0.3	-1.6	-1.2	-0.2	-0.6	0.2	0.3	0.6
Patch foraging water rate 12 sec	0.1	0.3	0.8	-0.6	-0.8	-0.7	-0.6	-0.7	-0.6	-0.9	-0.6	-0.2	0.4	0.1	-0.3	-0.0	-0.2
Patch foraging water rate 18 sec	0.0	0.1	0.3	0.1	0.2	0.2	0.0	0.5	0.4	0.1	-0.2	-0.4	0.2	-0.0	0.2	0.1	0.1
Patch foraging water rate 24 sec	0.2	0.3	1.5	-0.1	-0.1	-0.2	-0.5	0.1	0.2	0.1	-1.2	-0.9	-0.7	-0.3	0.5	0.6	0.7
Patch foraging water rate 6 sec	0.3	0.4	1.0	-0.8	-0.9	-0.8	-0.7	-0.7	-0.8	-1.0	-0.4	-0.1	0.4	0.3	-0.4	-0.1	-0.2
Seeking ratio, delayed vs. immediate footshock	0.4	0.4	1.1	0.7	0.8	0.7	0.5	0.2	0.6	0.8	0.5	-0.5	-0.6	-0.7	1.0	0.9	0.4
Distance traveled before self-admin	0.9	1.2	3.6	1.9	1.5	1.6	1.6	1.4	1.0	0.8	1.4	0.3	0.3	0.1	-0.5	-0.5	-0.6
Distance traveled after self-admin	1.1	1.4	4.7	2.2	1.5	1.7	1.7	1.2	1.2	1.3	1.2	-0.2	-0.7	-0.4	0.6	0.5	-0.0
Extensor digitorum longus weight	0.3	1.0	3.4	1.4	1.3	1.3	1.2	1.8	1.8	0.7	-0.4	-0.1	0.0	0.2	0.1	-0.5	-0.3
Bone: elastic displacement	0.4	0.4	1.0	-0.6	-0.7	-0.5	-0.7	-0.4	-0.3	-0.2	-0.7	-0.8	-0.8	-0.2	0.7	0.9	1.0
Bone: elastic work	0.5	0.7	2.1	0.2	0.0	0.2	-0.2	0.1	0.2	0.5	-0.8	-1.2	-1.3	-0.9	1.1	1.3	1.5
Bone: endosteal estimation	4.4	9.7	19.0	4.0	4.1	4.1	3.5	4.2	4.4	4.2	0.7	-1.3	-2.3	-2.0	2.2	1.4	1.2
Bone: endosteal perimeter	2.8	5.9	12.3	3.5	3.4	3.4	3.5	3.4	3.3	2.7	1.6	0.6	-0.3	-0.2	0.3	-0.7	-1.0
Epididymis fat weight	5.8	19.7	42.3	-5.8	-6.2	-6.2	-6.5	-6.0	-5.3	-4.8	-4.5	-2.2	-0.9	-0.7	0.5	2.0	2.2
Delta time in closed arm before/after self-admin	0.3	0.3	0.9	-0.0	-0.3	-0.2	-0.4	-0.1	0.1	-0.0	-0.5	-0.9	-0.6	-0.8	0.9	0.8	0.7
Delta time in open arm before/after self-admin	0.3	0.3	1.4	1.2	0.6	0.7	0.6	0.8	0.5	0.0	-0.2	-0.6	-0.2	-0.0	-0.2	0.2	0.0
Diff in mean of infusions in LGA sessions	2.2	2.7	4.7	-0.9	-0.9	-1.0	-0.2	-1.5	-1.8	-1.5	2.0	2.0	2.2	1.8	-2.1	-2.1	-1.8
Delay discount exponential model param	1.6	1.8	4.3	-0.1	0.0	-0.1	0.5	-0.7	-0.7	-0.8	1.7	2.1	1.8	1.6	-1.7	-1.9	-2.1
Extinction: sum of active levers before priming	1.2	1.3	2.6	-0.7	-0.7	-0.7	-0.1	-1.3	-1.4	-0.9	1.5	1.6	1.4	0.8	-1.4	-1.2	-1.3
Active lever presses in extinction session 6	1.2	1.2	3.8	-1.5	-1.5	-1.4	-1.2	-1.8	-1.9	-1.2	0.7	0.2	0.5	0.1	-0.4	-0.0	0.0
Bone: final force	1.2	1.9	4.3	0.1	-0.2	-0.2	-0.9	-0.1	0.2	0.3	-1.8	-2.0	-1.8	-2.1	1.7	2.0	2.0
Bone: final moment	1.0	1.6	3.8	0.3	-0.1	-0.1	-0.8	0.2	0.4	0.3	-1.8	-2.0	-1.6	-1.9	1.5	1.8	1.8
Food consumed during 24 hour testing period	1.1	1.5	3.2	1.6	1.6	1.6	1.6	1.4	1.4	1.8	0.9	-0.2	-0.9	-0.8	0.9	0.6	0.3
Glucose	4.1	6.4	14.2	3.2	3.3	3.3	3.8	3.3	3.0	2.4	2.5	1.7	0.8	1.2	-0.6	-1.7	-1.7
Heart weight	1.9	3.0	5.7	0.6	0.3	0.4	-0.5	1.0	1.4	0.9	-2.3	-2.4	-2.3	-2.4	2.2	2.3	2.2
Delay discount hyperbolic model param	1.6	1.8	4.3	-0.1	0.0	-0.1	0.5	-0.6	-0.7	-0.8	1.6	2.0	1.8	1.6	-1.7	-1.9	-2.1
Intermittent access intake day 1-15 change	0.0	0.0	0.1	0.1	0.2	0.1	-0.0	0.1	0.0	0.2	0.2	-0.3	-0.0	-0.0	0.1	0.1	0.1
Intermittent access intake escalation	0.1	0.2	0.6	-0.2	-0.1	-0.3	-0.5	-0.2	-0.2	0.1	-0.3	-0.8	-0.6	-0.5	0.6	0.7	0.7
Intermittent access intake escalation 2	0.6	0.7	1.9	1.2	1.2	1.1	0.9	1.4	1.2	0.9	0.2	-0.4	-0.2	-0.3	0.1	0.0	-0.0
Intermitt. access day 1 inactive lever presses	0.3	1.3	3.2	1.8	1.5	1.6	1.7	1.5	1.2	1.3	1.3	0.2	-0.0	-0.3	-0.0	-0.2	-0.2
Intermitt. access day 15 inactive lever presses	0.6	1.2	2.2	1.4	1.4	1.3	0.9	1.5	1.4	1.3	-0.3	-1.0	-0.9	-0.6	1.2	0.7	0.9
Intermitt. access escalation Index	1.4	2.0	5.8	-0.2	-0.4	-0.2	0.7	-0.9	-1.0	-0.4	2.4	2.4	1.8	1.4	-1.5	-1.6	-1.9
Intermittent access day 1 total infusions	0.6	0.9	1.8	-1.3	-1.3	-1.3	-1.2	-1.2	-1.3	-1.4	-0.9	-0.4	0.3	0.0	-0.2	0.1	0.3
Intermittent access day 15 total infusions	0.6	0.9	1.7	-1.0	-0.9	-1.0	-1.3	-0.9	-0.9	-0.6	-0.9	-1.3	-0.7	-0.5	0.8	1.0	1.1
Intermittent access terminal intake (last 3 days)	1.0	1.3	2.8	-1.1	-1.1	-1.2	-1.5	-0.7	-0.8	-0.8	-1.7	-1.7	-0.8	-0.6	1.0	1.1	1.3
Intermittent access total infusions	0.7	0.9	1.9	-0.9	-0.9	-0.9	-1.2	-0.6	-0.6	-0.7	-1.3	-1.4	-0.6	-0.5	0.8	1.0	1.1
Intermittent access day 1 locomotion	0.1	0.2	0.5	0.0	-0.1	-0.0	0.0	0.0	-0.2	0.1	-0.2	-0.7	-0.5	-0.5	0.6	0.6	0.7
Intermittent access day 15 total locomotion	1.3	2.3	4.2	0.7	0.8	0.8	0.2	1.1	1.1	1.5	-1.0	-2.1	-2.1	-2.0	2.1	2.0	2.0
Intermittent access total locomotion	1.6	1.9	3.9	0.8	0.7	0.7	0.2	0.9	0.9	1.3	-0.8	-2.0	-1.9	-1.9	2.0	1.9	1.8
Intermittent access standard deviation	0.8	1.7	5.7	-0.6	-0.4	-0.6	-1.2	0.5	0.3	-0.2	-2.4	-2.3	-1.2	-1.6	1.1	1.5	1.6
Left kidney weight	1.9	9.0	16.5	2.2	1.7	1.8	0.5	2.3	2.8	2.5	-2.4	-4.0	-4.1	-3.9	3.9	3.9	3.4
Right kidney weight	2.8	12.7	22.4	2.5	2.0	2.1	0.5	2.8	3.4	3.2	-2.9	-4.6	-4.7	-4.7	4.7	4.5	4.2
Cocaine induced anxiety	1.1	1.6	3.5	1.6	1.6	1.6	1.9	1.5	1.2	1.1	1.5	0.9	0.7	0.9	-0.6	-0.9	-1.0
Post-drug Anxiety	1.1	1.2	3.4	1.3	1.2	1.1	1.5	0.8	0.5	0.6	1.9	1.1	0.9	0.4	-0.8	-1.0	-1.1
Baseline Anxiety	1.5	1.8	4.8	-1.5	-1.6	-1.7	-1.3	-2.2	-2.0	-1.7	0.5	0.9	1.0	0.2	-0.8	-0.6	-0.8
Tail length	3.9	15.4	26.7	4.6	4.3	4.4	3.2	4.8	5.2	4.8	-0.8	-3.3	-3.9	-3.7	3.8	3.0	2.8
Length with tail	5.4	23.7	43.0	5.6	5.4	5.4	4.0	6.1	6.6	5.8	-1.4	-4.1	-4.9	-4.7	4.7	3.8	3.2
Length without tail	3.9	12.5	17.4	3.8	3.5	3.5	2.4	3.7	4.2	4.1	-0.8	-3.2	-4.1	-4.1	4.0	3.6	2.8
Times rat made contact with spout	2.1	2.4	4.5	-1.7	-1.9	-1.8	-1.4	-2.0	-2.1	-2.0	0.2	1.1	1.5	1.5	-1.5	-1.0	-0.9
Lifetime Intake	0.8	0.9	2.3	-0.7	-0.8	-0.8	-1.1	-0.4	-0.4	-0.5	-1.4	-1.5	-0.8	-0.9	1.0	1.1	1.2
Liver weight, left	3.3	5.4	13.1	3.6	3.1	3.3	3.2	3.0	2.9	3.0	1.8	0.1	-0.8	-1.0	0.9	0.2	-0.1
Liver weight, right	4.7	8.2	15.0	3.6	3.6	3.6	3.1	3.6	3.7	3.9	0.3	-1.4	-2.6	-2.3	2.4	1.7	1.5
Locomotor activity	2.9	4.5	11.0	3.2	3.0	2.9	2.5	3.3	3.1	2.5	0.4	-0.6	-0.8	-0.5	0.7	0.2	0.3
Locomotor testing distance	0.8	1.5	4.4	1.9	1.6	1.6	1.5	2.1	1.9	1.3	-0.0	-0.1	-0.2	0.6	0.0	-0.4	-0.0
Locomotor testing rearing	0.7	1.3	3.2	1.7	1.6	1.6	1.4	1.8	1.7	1.4	0.2	-0.4	-0.6	0.0	0.1	0.1	0.3
Locomotion in novel chamber	0.1	0.1	0.2	-0.1	0.1	0.2	0.2	0.4	0.4	0.1	-0.4	-0.3	-0.3	-0.4	0.4	0.3	0.2
Locomotion in novel chamber post-restriction	0.4	0.6	1.6	0.5	0.3	0.3	0.0	0.5	0.5	0.4	-0.4	-1.2	-0.9	-1.2	1.3	1.1	1.0
Fecal boli incidents, locomotor time 1	0.4	0.6	2.4	-0.2	-0.3	-0.3	0.0	-0.4	-0.4	-0.7	0.4	0.8	1.3	1.5	-1.0	-0.9	-0.9
Change in fecal boli incidents, locomotor task	1.1	1.1	3.0	0.4	0.5	0.5	0.2	0.6	0.7	1.4	-0.2	-0.9	-1.4	-1.7	1.5	1.3	1.3
Time >=10cm from walls, locomotor time 1	1.5	1.6	3.2	1.8	1.8	1.7	1.5	1.4	1.4	1.7	0.5	-0.5	-1.2	-0.6	0.9	0.6	0.6
Bouts of movement, locomotor time 1	0.4	0.5	0.9	0.6	0.7	0.7	0.6	0.9	0.7	0.0	0.1	0.4	0.8	0.7	-0.9	-0.9	-0.7
Total resting periods, locomotor time 1	0.3	0.4	1.0	0.7	0.9	0.8	0.7	1.0	0.8	0.4	0.2	0.1	0.5	0.4	-0.5	-0.5	-0.3
Rest time, locomotor task time 1	1.0	1.2	2.6	1.4	1.5	1.4	1.3	1.3	1.4	1.6	0.6	-0.4	-0.7	-0.7	0.7	0.6	0.5
Distance moved, locomotor task time 1	0.2	0.3	1.3	-0.7	-0.7	-0.7	-0.8	-0.4	-0.2	-0.7	-1.1	-0.4	-0.4	-0.4	0.2	0.1	0.2
Vertical activity count, locomotor time 1	0.1	0.2	0.7	-0.5	-0.5	-0.5	-0.5	-0.2	-0.2	-0.6	-0.8	-0.3	-0.1	-0.4	-0.1	-0.3	0.0
Time >=10cm from walls, locomotor time 2	0.6	0.9	1.5	1.1	1.1	1.2	0.9	1.1	1.2	1.0	-0.3	-0.7	-0.8	-0.9	0.9	0.7	0.6
Bouts of movement, locomotor time 2	1.3	2.1	5.0	2.0	2.2	2.2	1.9	1.9	1.8	1.7	0.6	-0.5	-0.8	-0.7	0.4	0.7	0.3
Total resting periods, locomotor time 2	1.5	2.6	6.1	2.3	2.5	2.5	2.2	2.1	2.0	1.8	0.9	-0.3	-0.6	-0.6	0.3	0.4	0.0
Rest time, locomotor task time 2	2.5	3.1	6.4	2.3	2.4	2.3	2.5	2.2	2.0	2.2	2.1	1.0	0.2	0.3	-0.4	-0.7	-0.8
Distance moved, locomotor task time 2	1.7	2.0	5.3	-1.7	-1.8	-1.8	-2.1	-1.3	-1.0	-1.4	-2.3	-1.2	-0.6	-0.6	0.8	0.9	1.0
Vertical activity count, locomotor time 2	0.4	0.6	1.3	-0.9	-1.1	-1.0	-1.0	-0.9	-0.8	-1.0	-1.1	-0.3	-0.1	-0.3	0.0	0.0	0.1
Light reinforcement 1	0.2	0.4	1.1	-1.0	-0.9	-0.8	-0.9	-0.7	-0.5	-0.6	-1.0	-0.3	-0.0	-0.0	0.1	0.3	0.2
Light reinforcement 2	1.5	2.3	4.8	0.9	1.1	1.1	0.5	1.4	1.7	1.6	-1.4	-1.8	-1.7	-1.8	2.2	1.8	1.5
Bone: marrow area	4.3	9.4	18.2	3.9	4.0	4.0	3.5	4.1	4.3	4.1	0.7	-1.3	-2.3	-2.0	2.2	1.4	1.2
Bone: maximum diameter	1.8	3.4	7.1	2.6	2.6	2.6	2.6	2.7	2.6	2.1	0.9	0.2	-0.2	-0.4	0.4	-0.3	-0.5
Bone: maximum force	1.0	1.9	4.2	0.7	0.3	0.4	-0.3	0.5	0.8	0.7	-1.6	-1.9	-2.0	-2.0	1.6	1.9	1.9
Bone: maximum moment	1.0	1.7	3.4	0.9	0.5	0.5	-0.1	0.8	1.0	0.7	-1.6	-1.8	-1.8	-1.9	1.5	1.6	1.7
Mean time between licks in bursts	1.3	3.1	6.6	2.4	2.6	2.5	2.6	2.5	2.2	2.0	1.5	0.4	-0.1	-0.1	0.1	-0.3	-0.6
Mean num. licks in bursts	1.3	2.1	4.8	-2.2	-1.9	-1.8	-1.7	-1.9	-1.9	-2.0	-0.8	0.4	0.9	0.7	-1.0	-0.6	-0.5
Cd content in liver	0.4	0.5	1.3	-1.0	-1.0	-0.9	-0.9	-0.7	-0.6	-0.9	-1.1	-0.3	0.2	-0.0	-0.1	-0.0	0.2
Co content in liver	1.0	1.1	2.4	-1.4	-1.4	-1.3	-1.6	-1.1	-0.9	-0.9	-1.4	-0.9	-0.4	-0.6	0.5	0.8	0.9
Cu content in liver	2.5	3.0	6.0	-2.2	-2.2	-2.1	-1.9	-2.2	-2.3	-2.4	-0.9	0.7	1.3	1.1	-1.5	-1.0	-0.8
Fe content in liver	0.7	0.8	1.5	-1.0	-1.0	-0.9	-1.1	-1.0	-0.7	-0.2	-0.8	-0.9	-0.8	-0.8	1.0	1.2	1.0
K content in liver	0.7	0.7	1.1	-0.8	-0.9	-0.8	-0.6	-0.9	-1.0	-1.0	0.0	0.8	0.8	0.9	-0.9	-0.8	-0.8
Mg content in liver	0.6	0.6	1.1	0.6	0.8	0.7	0.9	0.5	0.3	0.2	0.8	1.0	0.8	0.8	-0.9	-1.1	-1.0
Mn content in liver	3.0	3.3	6.3	2.1	2.2	2.1	2.5	1.8	1.4	1.3	2.4	1.8	1.3	1.4	-1.0	-1.7	-1.9
Na content in liver	0.8	0.8	1.8	-1.3	-1.2	-1.2	-1.3	-1.2	-1.1	-1.1	-1.1	-0.4	-0.3	0.0	-0.0	0.3	0.3
Rb content in liver	0.4	0.4	1.1	-0.5	-0.4	-0.3	-0.3	-0.4	-0.6	-0.9	-0.2	0.6	0.9	0.7	-1.0	-0.9	-0.8
Se content in liver	2.2	2.6	5.5	2.3	2.3	2.4	2.3	2.2	2.1	2.0	1.3	0.3	-0.3	-0.2	0.5	-0.1	-0.3
Sr content in liver	0.7	0.6	1.1	1.0	1.0	1.1	0.9	0.9	0.8	1.0	0.5	-0.4	-0.6	-1.0	0.5	0.5	0.4
Zn content in liver	0.2	0.2	0.5	0.4	0.4	0.5	0.6	0.5	0.4	-0.1	-0.1	0.5	0.5	0.4	-0.6	-0.7	-0.7
Bone: minimum diameter	2.4	4.3	9.1	3.0	2.9	3.0	2.9	2.8	2.8	2.6	1.4	0.2	-0.6	-0.6	0.6	-0.1	-0.4
Time in familiar zone, hab. session 1	3.4	3.3	6.4	-2.1	-2.2	-2.2	-1.8	-2.4	-2.5	-2.3	-0.4	1.2	1.3	1.7	-1.7	-1.2	-1.0
Time in novel zone, hab. session 1	2.8	2.8	6.9	2.1	2.0	2.0	1.6	2.6	2.6	1.8	-0.3	-1.3	-1.0	-1.3	1.3	0.9	0.8
Total zone transitions, hab. session 1	0.5	0.7	1.4	-0.6	-0.6	-0.5	-0.3	-0.5	-0.6	-0.9	0.2	1.0	1.1	1.1	-1.0	-1.2	-1.1
Total locomotion distance, hab. session 1	0.4	0.6	0.9	-0.6	-0.7	-0.7	-0.4	-0.8	-0.8	-1.0	0.3	0.8	0.9	1.0	-0.9	-0.9	-0.8
Locomotion velocity, hab. session 1	0.4	0.6	1.1	-0.8	-0.8	-0.8	-0.6	-1.0	-1.1	-0.9	0.3	0.7	0.8	0.7	-0.7	-0.7	-0.6
Time in familiar zone, hab. session 2	0.9	1.0	1.8	-0.8	-0.9	-0.9	-0.6	-1.3	-1.3	-1.1	0.3	0.9	0.9	1.0	-1.2	-0.9	-1.0
Time in novel zone, hab. session 2	0.9	0.9	1.8	0.5	0.5	0.5	0.1	1.0	1.1	0.8	-0.9	-1.2	-0.9	-1.1	1.3	1.1	1.2
Total zone transitions, hab. session 2	0.2	0.3	0.6	-0.6	-0.8	-0.8	-0.7	-0.8	-0.7	-0.5	0.0	0.2	0.2	0.1	-0.1	-0.1	-0.2
Total locomotion distance, hab. session 2	0.8	1.1	1.6	-1.0	-1.0	-1.0	-0.7	-1.1	-1.2	-1.1	0.5	1.0	1.2	1.3	-0.9	-1.0	-1.0
Locomotion velocity, hab. session 2	0.9	1.2	1.8	-1.0	-0.9	-1.0	-0.5	-1.1	-1.2	-1.2	0.7	1.2	1.3	1.3	-1.2	-1.2	-1.2
Novel to familiar place preference ratio	0.3	0.4	1.2	-0.6	-0.6	-0.5	-0.7	-0.2	-0.0	-0.2	-1.1	-0.8	-0.5	-0.5	0.6	0.6	0.8
Novelty place preference	0.5	0.5	1.4	-0.4	-0.3	-0.3	-0.6	0.1	0.2	0.1	-1.2	-1.0	-0.8	-0.8	0.9	0.9	1.0
Time in novel zone, NPP test	0.6	0.7	1.6	-0.2	-0.2	-0.1	-0.4	0.3	0.5	0.3	-1.3	-1.2	-1.0	-1.0	1.1	1.0	1.1
Total zone transitions, NPP test	0.5	0.7	1.8	-0.4	-0.6	-0.5	-0.1	-0.4	-0.4	-0.9	0.1	1.0	1.0	1.4	-1.1	-1.2	-1.2
Total locomotion distance, NPP test	0.8	1.1	1.9	-1.1	-1.2	-1.2	-0.8	-1.1	-1.1	-1.4	-0.1	0.8	1.0	1.3	-0.9	-0.9	-0.8
Locomotion velocity, NPP test	1.4	2.0	3.3	-1.4	-1.5	-1.4	-0.9	-1.5	-1.5	-1.7	0.2	1.3	1.5	1.8	-1.5	-1.4	-1.3
Intraocular pressure	0.3	0.5	1.1	-0.7	-0.2	-0.3	-0.2	-0.1	-0.3	-0.7	0.3	0.7	1.0	0.9	-0.9	-1.0	-0.9
Delta distance traveled before/after self-admin	1.1	1.1	2.9	0.2	0.2	0.2	-0.2	0.1	0.5	0.7	-1.2	-1.3	-1.7	-1.0	1.7	1.7	1.5
Delta ambulatory time before/after self-admin	0.6	0.8	2.2	0.4	0.4	0.4	0.1	0.2	0.6	0.9	-0.6	-0.8	-1.4	-0.9	1.5	1.3	1.0
Parametrial fat weight	0.5	1.1	2.7	0.8	0.4	0.5	0.1	0.6	0.7	0.8	-0.6	-1.4	-1.3	-1.7	1.4	1.4	1.2
Pavlov. Cond. lever latency	2.3	2.9	6.7	-2.6	-2.2	-2.2	-2.5	-2.0	-2.0	-2.0	-1.9	-0.9	-0.1	-0.5	-0.3	0.7	1.0
Pavlov. Cond. magazine entry latency	2.5	3.2	9.8	1.8	1.9	1.9	2.5	1.2	1.0	1.4	3.1	2.0	1.3	1.1	-0.9	-1.7	-1.8
Pavlov. Cond. change in total contacts	2.0	2.1	4.6	1.8	1.9	1.8	1.8	1.8	2.0	2.1	0.8	-0.3	-1.1	-0.8	1.3	0.6	0.3
Pavlov. Cond. index score	3.0	3.8	9.3	2.3	2.4	2.3	2.9	1.7	1.6	2.0	3.0	1.8	0.8	0.9	-0.4	-1.4	-1.6
Pavlov. Cond. latency score	2.9	3.7	8.1	2.4	2.5	2.4	2.8	1.9	1.8	2.1	2.8	1.6	0.6	0.7	-0.2	-1.2	-1.4
Pavlov. Cond. lever contacts	2.5	2.9	6.2	2.5	2.3	2.3	2.5	2.1	2.0	2.0	1.9	0.8	0.1	0.4	0.4	-0.6	-0.8
Pavlov. Cond. magazine entry number	2.3	2.9	9.8	-1.5	-1.5	-1.5	-2.2	-0.7	-0.5	-1.0	-3.1	-2.3	-1.5	-1.4	1.1	1.8	2.0
Pavlov. Cond. intertrial magazine entries	1.5	1.8	3.9	-1.6	-2.0	-1.9	-1.9	-1.7	-1.5	-1.9	-1.3	-0.3	0.7	0.4	-0.5	-0.1	0.1
Pavlov. Cond. lever-magazine prob. diff.	2.9	3.6	9.4	2.2	2.2	2.2	2.8	1.5	1.4	1.8	3.1	2.0	1.0	1.1	-0.6	-1.5	-1.7
Pavlov. Cond. response bias	2.7	3.3	8.5	2.2	2.1	2.0	2.7	1.4	1.3	1.7	2.9	1.9	0.9	1.0	-0.5	-1.4	-1.7
Pavlov. Cond. lever latency	0.4	0.5	1.2	0.5	0.6	0.6	0.5	0.4	0.6	1.1	0.0	-0.4	-1.0	-0.8	1.0	0.8	0.7
Pavlov. Cond. magazine entry latency	0.3	0.3	0.5	0.7	0.7	0.7	0.5	0.7	0.7	0.7	0.2	-0.4	-0.6	-0.5	0.5	0.4	0.2
Pavlov. Cond. change in total contacts	0.1	0.1	0.4	-0.1	-0.2	-0.2	-0.4	0.0	0.0	-0.2	-0.5	-0.6	-0.3	-0.5	0.3	0.4	0.4
Pavlov. Cond. index score	0.0	0.0	0.1	0.3	0.2	0.2	0.2	0.4	0.3	0.0	0.1	-0.1	0.1	0.0	-0.1	-0.2	-0.2
Pavlov. Cond. latency score	0.0	0.0	0.0	0.1	0.0	0.1	-0.0	0.2	0.1	-0.1	0.1	-0.1	0.0	-0.1	-0.0	-0.0	-0.1
Pavlov. Cond. lever contacts	0.2	0.3	0.8	-0.3	-0.5	-0.5	-0.5	-0.3	-0.4	-0.9	-0.2	0.2	0.7	0.5	-0.7	-0.6	-0.5
Pavlov. Cond. magazine entry number	0.2	0.2	0.6	-0.4	-0.3	-0.3	-0.0	-0.5	-0.5	-0.4	0.4	0.7	0.6	0.5	-0.8	-0.6	-0.5
Pavlov. Cond. intertrial magazine entries	0.8	1.2	2.8	1.2	1.2	1.1	1.5	0.9	0.7	0.7	1.7	1.2	0.9	0.7	-0.8	-1.0	-1.1
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.1	0.2	0.2	0.2	0.2	0.4	0.3	-0.0	0.0	-0.1	0.1	0.2	-0.1	-0.2	-0.2
Pavlov. Cond. response bias	0.1	0.1	0.2	0.3	0.2	0.2	0.2	0.4	0.2	-0.2	0.1	0.2	0.4	0.4	-0.4	-0.5	-0.4
Time in closed arm before self-admin	0.1	0.1	0.4	-0.6	-0.5	-0.6	-0.6	-0.5	-0.5	-0.2	-0.2	0.2	-0.1	-0.0	-0.3	-0.0	0.2
Time in closed arm after self-admin	1.5	1.6	2.4	-1.1	-1.1	-1.1	-1.5	-1.1	-0.8	-0.4	-1.3	-1.4	-1.4	-1.5	1.1	1.5	1.5
Time in open arm before self-admin	0.3	0.4	1.3	-0.1	0.3	0.3	0.6	0.1	0.2	0.3	1.0	1.1	0.8	0.0	-0.3	-0.8	-0.9
Time in open arm after self-admin	1.0	1.1	2.1	1.1	1.1	1.0	1.3	0.9	0.7	0.3	1.3	1.2	1.1	0.7	-0.9	-1.2	-1.5
Bone: periosteal estimation	2.8	5.9	11.3	3.0	3.0	3.0	2.3	3.2	3.4	3.0	-0.2	-1.6	-2.1	-2.2	2.0	1.5	1.4
Bone: periosteal perimeter	1.7	2.9	6.3	2.4	2.3	2.3	2.0	2.4	2.5	2.1	0.3	-0.5	-1.0	-1.2	1.0	0.4	0.2
Bone: post-yield work	1.9	2.8	5.9	2.3	2.3	2.3	2.4	2.4	2.2	1.5	1.2	0.8	0.4	0.1	-0.6	-1.0	-1.1
Progressive ratio test 1 active lever presses	0.6	0.7	1.5	-1.0	-1.1	-1.0	-1.0	-1.2	-1.1	-0.7	-0.6	-0.6	-0.4	-0.6	0.5	0.7	0.6
Progressive ratio test 1 breakpoint	0.6	0.7	1.4	-0.9	-1.0	-1.0	-1.0	-1.2	-1.0	-0.6	-0.6	-0.7	-0.5	-0.7	0.6	0.8	0.7
Progressive ratio test 1 inactive lever presses	1.3	1.8	3.7	-1.8	-1.9	-1.9	-1.9	-1.7	-1.7	-1.8	-1.1	-0.4	0.3	-0.5	-0.2	0.2	0.1
Progressive ratio test 2 active lever presses	0.9	1.1	2.4	-1.5	-1.5	-1.5	-1.5	-1.4	-1.5	-1.2	-0.4	-0.4	0.2	0.2	-0.1	0.3	0.4
Progressive ratio test 2 breakpoint	1.0	1.2	2.6	-1.6	-1.6	-1.6	-1.5	-1.5	-1.6	-1.2	-0.4	-0.5	0.1	0.1	0.0	0.3	0.5
Progressive ratio test 2 inactive lever presses	0.2	0.3	0.7	-0.2	-0.3	-0.3	-0.5	0.2	0.0	0.0	-0.7	-0.9	-0.4	-0.8	0.6	0.6	0.7
Incentive Sensitization - Responses	0.6	0.8	1.8	-1.2	-1.2	-1.2	-0.8	-1.1	-1.3	-1.0	0.5	0.5	0.9	0.8	-0.8	-0.6	-0.4
Incentive Sensitization - Breakpoint	0.7	0.9	1.9	-1.2	-1.2	-1.2	-0.9	-1.1	-1.4	-1.1	0.4	0.4	0.9	0.8	-0.8	-0.6	-0.3
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.7	0.3	0.2	0.2	0.5	-0.0	-0.2	-0.1	0.9	0.6	0.5	0.7	-0.3	-0.6	-0.5
Progressive ratio	1.7	2.7	7.4	0.4	-0.2	-0.1	-0.6	-0.1	0.4	1.1	-0.8	-2.2	-2.3	-2.6	2.4	2.7	2.1
Food seeking constrained by brief footshock	0.0	0.0	0.2	-0.5	0.2	-0.0	-0.4	-0.0	0.0	-0.2	-0.2	0.1	0.3	0.1	-0.1	-0.1	-0.1
Seeking ratio, punishment vs. effort	1.3	1.9	5.3	-0.5	0.2	0.1	0.3	0.1	-0.4	-1.1	0.5	1.8	2.0	2.1	-2.1	-2.3	-1.8
Retroperitoneal fat weight	0.3	1.5	3.7	0.6	0.4	0.4	-0.1	0.6	1.0	0.8	-1.2	-1.7	-1.5	-1.9	1.7	1.7	1.4
Reaction time number correct	0.9	1.7	4.2	-1.8	-1.6	-1.8	-2.0	-1.4	-1.1	-1.1	-1.6	-0.9	-0.5	-0.4	0.7	0.9	1.0
Reaction time mean minus median	2.4	6.0	14.1	3.6	3.5	3.5	3.8	3.1	2.8	2.6	2.4	0.8	-0.1	-0.2	0.1	-0.5	-0.8
Reaction time mean minus median AUC	1.5	3.9	8.6	2.9	2.8	2.8	2.9	2.7	2.4	2.1	1.7	0.5	-0.0	-0.4	-0.1	-0.5	-0.6
Reaction time num false alarms	0.2	0.2	0.5	0.6	0.6	0.5	0.3	0.6	0.7	0.7	-0.3	-0.1	-0.4	-0.2	0.3	0.1	0.4
Reaction time num false alarms AUC	0.2	0.3	0.7	0.7	0.8	0.6	0.4	0.8	0.9	0.8	-0.2	-0.1	-0.4	-0.1	0.4	0.1	0.4
Reaction time trials correct on left	0.9	1.7	4.2	-1.8	-1.6	-1.8	-2.0	-1.4	-1.1	-1.1	-1.6	-0.9	-0.5	-0.4	0.7	0.9	1.0
Reaction time trials on left	0.8	1.5	3.8	-1.7	-1.5	-1.7	-1.9	-1.2	-1.0	-1.0	-1.5	-0.9	-0.5	-0.5	0.8	0.9	1.0
Reaction time mean	3.6	5.7	13.3	3.4	3.3	3.4	3.7	3.1	2.6	2.2	2.5	1.1	0.5	0.7	-0.6	-1.2	-1.2
Reaction time mean AUC	3.5	5.7	12.9	3.4	3.4	3.4	3.6	3.2	2.8	2.3	2.4	0.9	0.4	0.6	-0.4	-1.1	-1.0
Median of all reaction times	2.6	3.7	8.5	2.7	2.6	2.6	2.9	2.5	2.0	1.6	2.0	1.0	0.6	0.9	-0.7	-1.2	-1.1
Reaction time omissions	2.6	3.8	7.9	2.7	2.8	2.7	2.8	2.4	2.2	2.4	2.3	0.8	-0.1	0.3	0.3	-0.3	-0.6
Reaction time false alarm rate	0.9	1.3	2.9	1.7	1.7	1.6	1.5	1.6	1.5	1.3	0.7	0.4	-0.1	0.1	-0.1	-0.5	-0.2
Reaction time premature initiation rate	0.3	0.4	1.2	0.3	0.2	0.3	0.0	0.3	0.5	0.6	-0.6	-0.9	-0.8	-0.8	1.1	0.9	0.9
Reaction time premature initiations	0.7	1.2	2.5	-0.8	-0.7	-0.7	-1.1	-0.5	-0.1	0.0	-1.4	-1.4	-1.2	-1.0	1.6	1.6	1.6
Std. dev. reaction times	3.6	6.6	14.5	3.8	3.7	3.7	3.8	3.5	3.1	2.8	2.4	0.5	-0.1	-0.1	0.2	-0.5	-0.6
Reaction time trials completed	0.8	1.5	3.8	-1.7	-1.5	-1.7	-1.9	-1.2	-1.0	-1.0	-1.5	-0.9	-0.5	-0.5	0.8	0.9	1.0
Reaction time trials AUC	0.8	1.5	3.8	-1.7	-1.6	-1.7	-2.0	-1.3	-1.1	-1.0	-1.5	-0.9	-0.5	-0.4	0.7	0.9	0.9
Run reversals in cocaine runway, females	0.5	0.5	1.4	-1.0	-0.7	-0.8	-0.8	-0.6	-0.7	-1.2	-0.7	0.2	0.6	0.3	-0.8	-0.5	-0.4
Run reversals in cocaine runway, males	3.6	3.6	7.2	2.6	2.6	2.7	2.4	2.4	2.6	2.5	0.7	-0.6	-1.2	-1.0	1.2	0.7	0.4
Latency to leave start box in cocaine runway	0.1	0.1	0.2	-0.5	0.0	-0.2	-0.4	0.0	-0.1	0.3	-0.1	-0.1	0.0	-0.0	0.3	0.1	0.4
Latency to leave start box in cocaine runway, F	0.2	0.3	1.0	-0.2	0.2	-0.1	0.0	0.1	0.0	-0.1	0.5	0.8	1.0	0.7	-0.6	-0.8	-0.8
Latency to leave start box in cocaine runway, M	1.4	1.3	4.0	-0.4	-0.1	-0.2	-0.8	0.1	0.1	0.8	-1.1	-1.6	-1.5	-1.4	1.5	1.6	2.0
Std. dev. time between licks in bursts	2.3	3.1	6.5	2.4	2.5	2.5	2.6	2.4	2.3	2.2	1.7	0.4	-0.1	-0.2	0.3	-0.3	-0.6
Total sessions with >9 infusions	0.6	0.7	1.5	-0.6	-0.7	-0.6	-0.9	-0.5	-0.5	-0.3	-1.1	-1.2	-0.8	-1.0	0.9	1.0	1.2
Short access day 1 total inactive lever presses	1.3	1.8	3.5	1.9	1.6	1.7	1.3	1.6	1.5	1.4	0.2	-1.1	-0.9	-1.6	1.1	0.9	0.6
Short access day 10 total inactive lever presses	0.6	1.5	3.4	0.5	0.2	0.3	1.0	0.1	-0.3	-0.3	1.7	1.8	1.7	1.0	-1.7	-1.7	-1.8
Short access day 1 total infusions	0.1	0.1	0.4	-0.3	-0.5	-0.4	-0.4	-0.3	-0.3	-0.6	-0.7	-0.5	-0.0	-0.2	0.1	0.1	0.2
Short access day 10 total infusions	0.5	0.7	1.4	-0.7	-0.7	-0.7	-0.9	-0.5	-0.5	-0.5	-1.2	-1.1	-0.7	-0.9	0.7	0.8	1.1
Short access total infusions	0.7	0.8	2.1	-0.6	-0.8	-0.7	-1.0	-0.5	-0.4	-0.5	-1.4	-1.4	-0.8	-1.0	0.9	1.0	1.1
Short access day 1 locomotion	0.3	0.4	0.8	-0.7	-0.7	-0.7	-0.4	-0.7	-0.7	-0.9	-0.3	0.5	0.7	0.4	-0.7	-0.7	-0.5
Short access day 10 total locomotion	0.7	1.3	2.1	1.3	1.4	1.5	1.2	1.4	1.4	1.4	-0.1	-0.8	-0.9	-1.2	1.0	0.7	0.7
Short access total locomotion	0.2	0.3	0.9	0.3	0.4	0.4	0.2	0.4	0.3	0.4	-0.4	-0.7	-0.6	-1.0	0.5	0.5	0.7
One hour access (0.3 mA shock)	1.0	1.1	2.1	-0.9	-0.9	-0.9	-0.4	-0.8	-1.1	-1.3	0.4	1.0	1.5	1.4	-1.5	-1.2	-1.1
Compulsive drug intake	2.6	3.1	9.2	0.2	0.4	0.4	1.3	-0.2	-0.5	0.0	2.6	3.0	2.1	2.3	-2.3	-2.5	-2.2
One hour access (shock baseline)	0.4	0.7	2.6	-0.2	-0.4	-0.4	-0.8	0.1	-0.0	-0.6	-1.4	-1.6	-0.6	-0.7	0.9	1.0	0.9
Social response proportion	0.3	0.3	0.8	0.8	0.9	0.8	0.7	0.8	0.7	0.4	0.2	0.0	0.1	0.3	-0.3	-0.2	-0.2
Social responses	0.1	0.1	0.2	0.4	0.4	0.4	0.2	0.2	0.2	0.2	-0.2	-0.3	-0.3	-0.2	0.1	0.3	-0.0
Social time	3.1	4.2	9.8	2.8	2.9	2.9	3.1	2.1	1.7	2.2	3.0	1.2	0.1	-0.0	-0.4	-0.8	-0.9
Soleus weight	2.5	7.4	16.2	3.8	3.8	3.9	4.0	3.9	3.7	3.2	1.8	0.6	-0.5	0.3	0.4	-0.5	-0.7
Bone: stiffness	0.2	0.3	0.6	-0.6	-0.5	-0.5	-0.6	-0.7	-0.5	-0.3	-0.6	-0.4	-0.5	-0.8	0.3	0.6	0.5
Tibialis anterior weight	0.4	1.4	3.3	-1.7	-1.8	-1.7	-1.6	-1.4	-1.2	-1.4	-1.3	-0.3	0.0	0.5	0.1	0.2	0.5
Time to tail flick, vehicle, before self-admin	1.2	1.3	5.9	1.1	1.1	0.9	1.1	0.0	-0.2	0.4	2.4	1.4	0.9	0.9	-1.0	-1.1	-1.2
Time to tail flick, vehicle, after self-admin	0.5	0.7	2.3	0.2	0.6	0.5	0.8	-0.0	-0.0	0.2	1.3	1.5	0.7	0.7	-0.9	-1.0	-1.2
Time to tail flick, test, before self-admin	0.1	0.1	0.2	-0.4	-0.3	-0.3	-0.4	-0.5	-0.3	-0.2	0.3	0.1	0.4	-0.2	-0.1	-0.1	-0.3
Time to tail flick, test, after self-admin	0.9	1.0	3.6	1.6	1.1	1.2	1.5	0.3	0.1	0.3	1.9	0.8	0.2	-0.7	-0.5	-0.5	-0.9
Delta time to tail flick, vehicle, before/after SA	0.6	0.5	2.0	-1.4	-1.1	-1.0	-0.8	-0.6	-0.4	-0.6	-1.3	-0.1	-0.0	0.0	0.1	0.1	0.2
Delta time to tail flick, test, before/after SA	0.2	0.3	0.5	0.2	-0.2	-0.1	0.2	-0.5	-0.7	-0.5	0.7	0.7	0.3	0.3	-0.7	-0.5	-0.5
Tibia length	2.6	7.2	13.2	3.5	3.2	3.2	2.6	3.2	3.4	3.6	0.2	-1.5	-2.5	-2.5	2.4	1.9	1.6
Ambulatory time before self-admin	0.3	0.5	1.6	1.3	0.9	1.0	1.0	0.8	0.5	0.4	1.1	0.1	0.3	0.1	-0.5	-0.4	-0.4
Ambulatory time after self-admin	1.0	1.2	3.9	2.0	1.4	1.5	1.5	1.0	0.9	1.2	1.2	-0.1	-0.7	-0.3	0.6	0.5	0.0
Bone: tissue strength	0.3	0.3	0.8	0.1	0.0	0.1	-0.2	0.1	0.3	0.2	-0.6	-0.9	-0.9	-0.8	0.8	0.8	0.7
Total heroin consumption	0.5	0.6	2.0	1.0	0.7	0.8	1.1	0.5	0.3	0.2	1.4	0.6	0.4	0.5	-0.5	-0.5	-0.9
Bone: trabecular number	1.1	1.8	3.5	-1.7	-1.7	-1.6	-1.2	-1.6	-1.6	-1.9	-0.9	0.8	1.0	1.4	-1.2	-0.9	-0.7
Bone: trabecular spacing	2.4	3.2	6.1	1.8	1.6	1.6	0.9	1.7	1.9	2.1	-0.3	-1.8	-1.9	-2.5	2.2	1.9	1.8
Bone: trabecular thickness	1.2	1.5	2.7	-1.3	-1.2	-1.2	-0.8	-1.1	-1.2	-1.5	-0.0	1.1	1.4	1.7	-1.4	-1.3	-1.1
Bone: trabecular tissue density	0.8	1.1	2.7	-0.1	0.1	-0.0	-0.7	0.5	0.6	0.4	-1.5	-1.6	-1.3	-1.4	1.1	1.4	1.6
Water consumed over 24 hours	0.1	0.1	0.4	0.3	0.4	0.5	0.6	0.3	0.3	0.6	0.6	0.1	-0.2	-0.1	0.2	0.1	-0.1
Number of responses in last shaping day	0.5	0.6	1.4	0.7	0.5	0.5	-0.0	0.6	1.0	0.4	-1.2	-0.9	-1.0	-0.7	1.1	0.9	0.5