Hub : Genes

Mkrn2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Mkrn2 0.1 0.05 1.1e-05 0.06 0.07 0.06 0.06 7.6e-06 5.3e-06 3.1e-05 1.3e-05
2 pVTA mRNA stability Mkrn2 0.1 0.06 3.0e-06 0.04 0.06 0.06 0.06 5.6e-04 1.3e-05 7.6e-06 7.8e-06
3 IC gene expression Mkrn2 0.1 0.06 5.3e-03 0.06 0.04 0.05 0.06 2.0e-03 1.3e-02 3.8e-03 1.1e-03
4 pVTA alternative TSS NM_001008314.1 0.09 0.06 2.3e-03 0.05 0.03 0.04 0.04 9.5e-05 4.1e-03 2.0e-04 2.8e-04
5 pVTA alternative TSS NM_001008314.1 0.08 0.05 8.8e-03 0.04 0.02 0.04 0.03 4.3e-04 7.9e-03 5.5e-04 1.3e-03
6 Brain isoform ratio XM_039107424.2 0.05 0.04 7.6e-04 0.01 0.03 0.03 0.03 1.7e-02 5.5e-04 3.7e-04 8.1e-04
7 Adipose mRNA stability Mkrn2 0.16 0.08 0.0e+00 0.16 0.16 0.15 0.16 2.6e-17 8.7e-18 1.3e-16 7.6e-18
8 NAcc intron excision ratio chr4_150343395_150344161 0.01 0.01 6.2e-03 0 0 -0 -0 1.3e-01 1.1e-01 9.2e-01 4.0e-01
9 OFC mRNA stability Mkrn2 0.18 0.11 4.0e-03 0.08 -0.01 0.03 0.04 6.6e-03 4.8e-01 5.5e-02 4.2e-02
10 NAcc mRNA stability Mkrn2 0.14 0.06 0.0e+00 0.13 0.15 0.12 0.14 3.1e-19 1.2e-21 1.3e-17 1.0e-20
11 BLA mRNA stability Mkrn2 0.18 0.08 4.1e-13 0.22 0.22 0.22 0.21 8.1e-12 8.1e-12 1.1e-11 1.4e-11
12 Adipose alternative polyA XM_039107421.2 0.04 0.02 5.7e-03 0.01 0.02 0.03 0.02 1.6e-02 2.2e-03 4.1e-04 9.1e-04
13 Adipose alternative polyA NM_001008314.1 0.04 0.03 4.5e-03 0.01 0.02 0.03 0.03 1.6e-02 1.5e-03 3.3e-04 7.7e-04
14 Adipose alternative polyA XM_039107424.2 0.04 0.03 4.3e-03 0.01 0.02 0.03 0.03 1.6e-02 1.4e-03 3.2e-04 7.3e-04
15 NAcc gene expression Mkrn2 0.45 0.11 0.0e+00 0.17 0.17 0.16 0.17 2.9e-25 2.3e-24 5.2e-24 8.6e-25
16 Adipose alternative polyA NM_001008314.1 0.04 0.02 6.6e-03 0.01 0.02 0.02 0.02 1.7e-02 2.4e-03 2.6e-03 1.0e-03
17 Brain mRNA stability Mkrn2 0.26 0.04 0.0e+00 0.41 0.4 0.41 0.42 8.7e-41 7.5e-40 2.2e-41 7.8e-42
18 LHb mRNA stability Mkrn2 0.16 0.09 2.8e-03 0.05 0.08 0.01 0.07 2.4e-02 5.2e-03 2.1e-01 1.1e-02
19 BLA gene expression Mkrn2 0.36 0.18 2.7e-06 0.12 0.11 0.13 0.12 3.9e-07 2.7e-06 1.5e-07 6.0e-07
20 PL gene expression Mkrn2 0.1 0.05 8.4e-10 0.09 0.09 0.07 0.08 9.8e-10 1.5e-09 3.8e-08 3.5e-09
21 Liver gene expression Mkrn2 0.11 0.06 1.9e-08 0.06 0.06 0.06 0.06 2.1e-07 1.2e-07 7.9e-07 6.4e-07
22 PL mRNA stability Mkrn2 0.35 0.12 0.0e+00 0.26 0.26 0.28 0.27 3.3e-28 8.7e-29 4.2e-30 5.6e-29
23 Brain gene expression Mkrn2 0.03 0.02 1.6e-03 0.01 0.02 0 0.02 1.3e-02 1.0e-02 9.6e-02 8.9e-03
24 pVTA intron excision ratio chr4_150344342_150345209 0.04 0.03 4.9e-03 0.02 0.01 0.03 0.02 9.1e-03 2.2e-02 2.4e-03 6.4e-03
25 IL mRNA stability Mkrn2 0.39 0.16 3.2e-07 0.18 0.21 0.29 0.23 4.0e-05 9.0e-06 1.1e-07 2.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.10.31.30.5-0.20.0-1.1-1.11.00.50.6-0.10.5-0.1-0.10.2-0.2-0.2-0.10.10.6-0.3-0.3-0.3-0.40.6-0.20.7
Area under the delay curve0.10.20.7-0.10.6-0.00.30.30.00.00.20.20.00.0-0.80.8-0.80.3-0.8-0.20.2-0.30.10.2-0.10.6-0.20.2
BMI with tail0.82.87.0-2.32.2-2.42.52.5-2.6-1.7-2.31.2-1.81.0-1.91.8-1.81.3-1.7-0.9-1.90.30.80.50.7-0.40.8-0.3
BMI without tail0.10.72.5-1.01.2-1.61.01.0-1.3-0.4-1.10.4-0.6-0.2-1.21.2-1.20.4-1.1-0.2-0.9-0.1-0.1-0.5-0.2-0.30.30.1
Body weight0.62.68.4-1.51.9-2.52.32.3-2.0-1.0-1.40.4-0.80.2-2.92.8-2.80.5-2.8-0.2-1.0-0.5-0.1-0.7-0.20.4-0.1-0.3
Weight adjusted by age0.20.52.3-0.61.2-0.8-0.1-0.1-0.5-0.4-0.60.9-0.50.6-0.50.5-0.51.0-0.5-0.9-0.51.50.90.00.6-0.00.50.9
Bone surface0.40.72.80.80.0-0.5-1.7-1.71.50.80.9-0.30.8-0.1-0.70.8-0.8-0.5-0.70.20.8-0.4-0.3-0.7-0.71.0-0.40.8
Bone volume0.20.41.20.7-0.30.1-1.1-1.11.10.70.8-0.30.7-0.3-0.20.2-0.2-0.5-0.20.30.8-0.4-0.4-0.5-0.50.8-0.40.5
Breakpoint value in progressive ratio session0.10.31.6-0.1-0.40.11.31.3-0.3-0.20.4-0.30.0-0.1-0.20.2-0.20.0-0.30.30.5-0.5-0.30.5-0.11.0-0.6-0.4
Number of licking bursts0.20.71.80.9-1.11.3-1.1-1.10.81.00.5-0.90.7-0.90.9-0.90.9-0.70.90.80.4-0.6-0.8-0.8-0.7-0.6-0.3-0.4
Context. condit. distance diff. score1.31.65.1-1.61.7-1.51.91.9-2.3-1.3-1.71.5-1.50.6-0.10.1-0.11.60.0-0.9-1.50.60.60.50.9-0.91.01.0
Locomotion velocity, session 10.30.30.70.7-0.80.9-0.2-0.20.40.60.7-0.80.6-0.50.6-0.60.5-0.80.50.60.6-0.6-0.5-0.3-0.30.2-0.5-0.2
Locomotion distance, session 11.31.73.91.3-1.0-0.4-0.8-0.80.71.61.1-2.01.5-1.5-0.90.9-0.9-1.8-0.91.71.1-1.3-1.5-1.8-1.60.9-1.4-1.4
Locomotion velocity, session 20.60.71.61.1-0.70.6-1.2-1.21.31.21.0-1.01.0-0.9-0.00.0-0.0-0.7-0.10.80.9-1.0-0.9-0.8-0.90.5-0.90.1
Locomotion distance, session 22.94.08.02.1-1.4-0.2-1.2-1.21.72.32.0-2.82.3-2.2-1.51.6-1.6-2.1-1.62.42.1-2.7-2.5-2.4-2.61.9-2.2-1.3
Locomotion velocity, session 30.80.93.20.2-0.41.2-1.3-1.30.40.1-0.30.2-0.20.41.8-1.81.80.21.8-0.2-0.50.10.30.60.4-1.40.80.2
Locomotion distance, session 30.30.31.90.00.4-0.2-1.4-1.40.40.2-0.50.2-0.10.20.3-0.40.40.60.4-0.3-0.60.00.2-0.3-0.1-1.10.60.5
Stereotopy head waving bouts, day 30.70.83.31.1-1.41.8-0.4-0.40.60.91.0-0.70.9-1.01.2-1.11.1-1.01.00.81.0-0.6-0.9-0.6-0.6-0.0-0.6-0.2
Stereotopy head waving duration, day 30.81.02.31.3-1.51.5-0.2-0.20.91.11.5-1.11.2-1.00.3-0.30.3-1.50.21.11.5-0.8-1.1-0.7-0.81.0-1.2-1.0
Locomotion velocity, session 70.30.31.80.20.4-0.7-1.3-1.31.10.30.20.10.20.2-0.80.8-0.7-0.0-0.8-0.00.20.10.2-0.2-0.20.5-0.1-0.0
Locomotion distance, session 70.10.10.3-0.30.5-0.5-0.2-0.20.2-0.3-0.20.2-0.20.5-0.60.5-0.60.4-0.5-0.1-0.2-0.20.20.50.00.20.10.1
Stereotopy head waving bouts, day 70.50.62.21.0-0.70.7-1.5-1.51.11.10.7-0.50.8-0.80.5-0.50.5-0.40.50.50.6-0.4-0.6-0.8-0.7-0.2-0.4-0.1
Stereotopy head waving duration, day 70.81.02.21.3-0.90.7-1.4-1.41.31.51.1-0.91.2-1.30.3-0.30.3-0.80.21.01.0-0.8-1.0-1.3-1.00.2-0.9-0.2
Locomotion velocity, session 80.30.42.10.5-0.0-0.6-0.1-0.10.00.80.3-0.70.6-1.0-0.50.5-0.5-0.3-0.50.80.4-0.7-0.9-1.4-0.80.1-0.7-0.2
Locomotion distance, session 80.60.92.80.20.2-1.40.90.9-0.80.70.0-0.90.5-1.3-1.11.1-1.1-0.3-1.01.20.3-1.7-1.6-1.4-1.30.5-0.8-0.4
Degree of sensitization distance0.30.32.00.2-0.60.40.80.80.3-0.00.8-0.30.3-0.0-0.40.5-0.5-0.7-0.60.40.8-0.5-0.30.5-0.11.4-0.7-0.4
Degree of sensitization stereotypy0.10.10.60.2-0.00.2-0.8-0.80.40.4-0.0-0.00.1-0.30.4-0.40.40.30.4-0.0-0.10.0-0.1-0.3-0.1-0.50.10.3
Conditioned locomotion2.63.19.7-1.40.80.60.20.2-1.5-1.4-2.11.6-1.81.52.2-2.32.31.72.4-1.5-2.31.31.51.51.7-3.12.21.2
Cocaine response after cond. corrected3.34.98.42.8-2.82.8-2.0-2.02.12.82.3-2.42.5-2.81.3-1.31.2-1.91.12.82.1-2.8-2.9-2.2-2.60.0-1.9-1.2
Cocaine response after cond. not corrected3.75.49.73.0-3.03.1-2.5-2.52.62.82.6-2.42.6-2.51.7-1.61.6-2.21.52.62.3-2.6-2.6-1.9-2.30.3-1.8-1.3
Cocaine response before conditioning0.30.31.3-0.00.1-0.1-0.6-0.60.8-0.40.40.4-0.01.1-0.20.2-0.2-0.5-0.2-0.70.41.11.10.70.81.00.2-0.0
Saline control response0.81.13.0-0.30.80.2-1.7-1.70.9-0.5-0.51.1-0.71.21.0-1.01.01.41.1-1.2-0.71.01.21.30.9-0.91.31.0
Bone: connectivity density0.60.92.00.9-0.4-0.5-1.0-1.01.21.01.1-1.01.1-0.7-1.11.1-1.1-1.0-1.10.71.1-0.6-0.7-1.0-1.01.4-0.9-0.1
Bone: cortical apparent density0.20.30.90.7-0.60.5-0.7-0.70.90.50.9-0.90.7-0.3-0.00.1-0.1-0.5-0.10.50.8-0.4-0.3-0.2-0.40.8-0.50.2
Bone: cortical area0.10.20.70.1-0.00.2-0.5-0.50.4-0.10.20.6-0.00.30.4-0.40.40.10.4-0.50.20.80.40.10.40.10.20.8
Bone: cortical porosity0.50.51.20.8-0.80.6-0.1-0.10.80.61.1-0.60.9-0.5-0.50.5-0.5-1.1-0.60.81.1-0.7-0.6-0.4-0.61.1-1.0-0.7
Bone: cortical porosity0.40.41.60.4-0.40.00.30.30.40.20.8-0.20.5-0.2-1.01.0-1.0-0.8-1.10.40.9-0.2-0.2-0.2-0.31.3-0.8-0.4
Bone: cortical thickness0.30.51.40.8-0.91.2-0.7-0.70.80.50.8-0.30.6-0.41.1-1.11.1-0.31.00.30.7-0.0-0.4-0.1-0.20.2-0.20.6
Bone: cortical thickness0.81.04.30.2-0.61.5-0.8-0.80.60.10.10.2-0.20.22.1-2.02.00.42.1-0.4-0.10.10.21.00.5-0.80.51.2
Bone: cortical tissue density0.20.30.90.7-0.60.5-0.6-0.60.90.50.9-0.90.7-0.3-0.10.1-0.1-0.5-0.20.50.8-0.5-0.3-0.2-0.40.8-0.60.2
Condit. Reinf. active minus inactive responses0.81.05.01.1-1.00.9-2.2-2.22.20.71.2-0.60.90.30.2-0.20.2-1.00.10.21.00.10.20.0-0.20.8-0.4-0.3
Condit. Reinf. active-inactive response ratio1.31.46.31.5-1.51.4-2.5-2.52.40.91.3-0.91.10.10.9-0.90.9-1.10.80.61.0-0.3-0.1-0.3-0.40.3-0.30.0
Condit. Reinf. active responses0.20.31.40.10.1-0.1-1.2-1.21.0-0.20.20.3-0.00.8-0.30.3-0.3-0.1-0.4-0.50.00.70.70.60.30.40.20.0
Condit. Reinf. inactive responses0.60.81.8-1.21.3-1.00.80.8-1.1-0.9-1.11.2-1.10.7-0.60.5-0.51.0-0.5-1.1-1.10.80.80.60.8-0.50.70.5
Incentive salience index mean1.31.76.01.7-1.81.4-2.2-2.22.51.31.7-1.31.5-0.40.4-0.30.3-1.60.20.91.5-0.7-0.6-0.5-0.80.9-1.0-0.7
Condit. Reinf. lever presses1.21.84.51.7-2.11.6-1.1-1.11.61.51.7-1.81.6-1.10.3-0.30.3-2.00.21.51.6-1.4-1.3-1.0-1.20.7-1.4-1.0
Condit. Reinf. active minus inactive responses0.71.13.81.4-1.21.0-1.7-1.72.01.11.5-0.91.3-0.50.1-0.10.0-1.2-0.10.91.3-0.7-0.7-0.7-0.80.8-0.8-0.1
Condit. Reinf. active-inactive response ratio1.21.94.71.7-2.01.6-0.9-0.91.91.32.2-1.41.7-0.9-0.00.1-0.1-2.1-0.31.32.1-0.8-1.1-0.7-1.01.7-1.6-1.2
Condit. Reinf. active responses0.20.32.20.6-0.30.5-1.5-1.51.20.40.5-0.10.40.10.4-0.40.4-0.10.30.10.3-0.3-0.1-0.2-0.3-0.20.10.8
Condit. Reinf. inactive responses1.11.64.2-1.21.8-1.2-0.7-0.7-0.6-1.0-1.71.5-1.41.20.3-0.30.32.10.4-1.3-1.80.61.10.80.9-1.81.72.1
Condit. Reinf. lever presses0.20.41.00.8-0.71.0-0.9-0.90.90.70.7-0.40.6-0.30.7-0.70.7-0.20.60.40.6-0.5-0.5-0.1-0.4-0.1-0.3-0.0
Condit. Reinf. lever reinforcers received0.40.53.20.9-0.40.4-1.8-1.81.50.70.7-0.30.7-0.20.2-0.20.2-0.20.20.30.6-0.4-0.3-0.5-0.50.1-0.20.6
Conditioned reinforcement - actives0.72.95.7-2.42.3-1.71.61.6-2.0-2.2-2.01.9-2.12.1-1.01.0-1.01.9-0.9-1.8-1.91.21.72.01.6-0.31.40.2
Conditioned reinforcement - inactives0.00.11.0-0.20.3-0.3-0.0-0.00.1-0.30.00.6-0.20.20.2-0.20.20.30.2-0.50.00.30.30.20.30.20.21.0
Conditioned locomotion0.20.30.9-0.30.8-0.90.20.2-0.2-0.3-0.20.3-0.20.3-1.00.9-0.90.4-0.9-0.3-0.1-0.30.00.0-0.00.40.10.2
Patch foraging indifference point 0 sec0.10.31.5-0.80.9-1.20.20.2-0.6-0.7-1.00.2-0.70.7-0.50.5-0.50.4-0.4-0.2-0.90.10.20.40.1-0.20.6-0.2
Patch foraging indifference point AUC0.30.73.30.8-1.21.8-0.9-0.90.70.60.6-0.50.5-0.31.3-1.31.3-0.61.20.40.4-0.0-0.30.0-0.1-0.7-0.1-0.6
Delay disc. indifference point, 0s delay1.11.22.9-1.31.7-0.90.80.8-0.9-1.1-0.91.3-1.11.3-0.90.9-0.91.5-0.9-1.3-0.81.21.21.51.00.60.80.9
Delay disc. indifference point, 16s delay0.20.20.80.10.2-0.60.10.10.20.30.3-0.20.2-0.5-0.80.8-0.8-0.1-0.80.20.4-0.5-0.2-0.1-0.50.9-0.6-0.6
Delay disc. indifference point, 2s delay1.31.43.8-1.11.7-1.21.31.3-0.6-1.0-0.41.0-0.71.0-1.91.9-1.91.1-1.9-1.1-0.20.91.10.90.71.40.20.6
Delay disc. indifference point, 24s delay0.40.72.00.6-0.0-0.5-0.9-0.90.51.10.4-0.80.8-1.3-0.80.8-0.8-0.8-0.70.80.4-1.2-0.9-1.4-1.20.1-0.8-0.3
Delay disc. indifference point, 4s delay0.30.30.7-0.60.8-0.10.80.8-0.6-0.4-0.40.7-0.50.3-0.40.3-0.40.8-0.3-0.7-0.30.70.50.50.50.10.40.3
Delay disc. indifference point, 8s delay0.10.20.40.40.00.5-0.4-0.40.60.40.6-0.20.5-0.2-0.50.5-0.5-0.2-0.60.20.6-0.7-0.3-0.4-0.40.4-0.40.5
Indifference point function ln k0.30.82.3-0.50.9-1.41.51.5-0.8-0.4-0.10.3-0.1-0.0-1.51.5-1.50.2-1.40.00.2-0.3-0.2-0.2-0.21.3-0.40.1
Indifference point function log k0.30.82.3-0.50.9-1.41.51.5-0.8-0.4-0.10.3-0.1-0.0-1.51.5-1.50.2-1.40.00.2-0.3-0.2-0.2-0.21.3-0.40.1
Patch foraging total patch changes 0 sec0.10.31.3-0.80.7-1.10.50.5-0.7-0.8-0.90.0-0.60.6-0.70.7-0.60.2-0.6-0.1-0.80.00.10.40.1-0.00.4-0.6
Patch foraging total patch changes 12 sec0.30.42.00.5-0.90.9-0.6-0.60.50.40.2-0.90.3-0.40.8-0.80.8-0.50.80.70.1-0.5-0.60.0-0.5-0.4-0.1-1.4
Patch foraging total patch changes 18 sec0.10.10.60.0-0.3-0.1-0.8-0.80.2-0.0-0.3-0.3-0.10.30.1-0.10.1-0.30.20.1-0.40.10.00.1-0.1-0.50.4-0.8
Patch foraging total patch changes 24 sec0.31.02.1-1.21.0-0.2-0.0-0.0-0.7-1.2-1.41.0-1.31.40.3-0.40.41.00.4-1.2-1.51.01.11.41.1-1.11.40.7
Patch foraging total patch changes 6 sec0.20.40.8-0.80.4-0.70.60.6-0.7-0.8-0.80.6-0.90.70.5-0.50.50.50.6-0.6-0.80.70.50.90.7-0.20.7-0.3
Patch foraging time to switch 0 sec0.20.61.8-0.81.2-1.40.40.4-0.5-0.7-0.70.8-0.70.8-0.60.6-0.61.1-0.5-0.9-0.61.11.00.60.80.40.50.3
Patch foraging water rate 0 sec0.31.03.90.9-1.30.3-0.1-0.10.30.70.7-1.51.0-0.9-0.30.3-0.3-1.9-0.31.40.7-1.6-1.4-0.8-1.30.3-0.9-2.0
Patch foraging water rate 12 sec0.10.41.00.5-0.70.10.60.6-0.10.50.5-0.80.6-0.9-0.40.4-0.5-0.9-0.50.80.6-1.0-1.0-0.6-0.80.6-0.8-0.5
Patch foraging water rate 18 sec0.10.20.9-0.4-0.00.30.90.9-0.8-0.6-0.40.2-0.40.40.3-0.30.30.00.3-0.1-0.4-0.10.00.60.3-0.20.3-0.2
Patch foraging water rate 24 sec0.60.82.20.9-1.20.80.20.2-0.00.70.8-1.20.9-1.10.0-0.0-0.0-1.5-0.01.30.8-1.4-1.4-0.8-1.2-0.0-0.9-1.5
Patch foraging water rate 6 sec1.31.96.01.2-1.40.4-0.0-0.00.31.41.0-1.91.4-1.8-0.40.4-0.4-1.9-0.42.01.0-2.4-2.1-1.4-1.90.5-1.4-2.0
Seeking ratio, delayed vs. immediate footshock0.81.12.6-1.41.0-0.51.31.3-1.4-1.6-1.21.1-1.31.4-0.10.1-0.11.0-0.1-1.2-1.01.31.11.01.2-0.60.90.7
Distance traveled before self-admin0.30.72.81.0-0.4-1.6-0.9-0.91.10.91.0-0.80.9-0.7-0.40.5-0.4-0.6-0.40.60.9-0.2-0.7-1.0-0.81.7-0.7-0.5
Distance traveled after self-admin0.10.11.0-0.00.0-0.0-0.3-0.30.6-0.30.2-0.2-0.10.70.0-0.00.00.5-0.0-0.20.0-0.20.31.00.30.40.10.1
Extensor digitorum longus weight2.911.532.8-4.24.1-4.35.75.7-4.7-4.1-3.02.8-3.22.9-3.43.4-3.42.4-3.2-2.8-2.33.02.82.12.71.41.4-0.2
Bone: elastic displacement0.81.02.5-1.11.4-1.00.10.1-0.4-1.1-0.91.1-1.11.3-0.10.1-0.11.60.0-1.3-0.91.11.31.11.1-0.21.11.5
Bone: elastic work0.30.41.7-0.50.9-1.30.40.40.0-0.30.10.5-0.20.4-1.01.0-1.00.5-0.9-0.60.20.40.50.30.41.3-0.10.8
Bone: endosteal estimation0.41.03.2-1.01.4-1.80.30.3-0.4-0.8-0.71.4-0.91.0-1.51.5-1.40.7-1.5-1.2-0.61.01.00.60.50.40.30.5
Bone: endosteal perimeter0.30.72.0-0.70.8-0.4-0.5-0.50.0-0.8-0.61.3-0.81.40.2-0.20.20.80.2-1.4-0.71.41.20.81.0-0.50.90.7
Epididymis fat weight0.41.97.5-1.42.2-2.70.20.2-0.8-1.0-1.41.1-1.11.0-2.12.0-2.01.5-1.9-1.0-1.20.71.10.00.60.20.81.7
Delta time in closed arm before/after self-admin0.30.32.70.4-0.2-1.2-0.2-0.20.50.40.60.10.4-0.3-0.00.1-0.0-0.40.10.10.60.8-0.1-0.7-0.11.6-0.40.1
Delta time in open arm before/after self-admin0.10.10.5-0.20.10.40.40.4-0.6-0.2-0.3-0.30.00.0-0.70.6-0.7-0.1-0.70.2-0.2-0.3-0.1-0.5-0.1-0.6-0.1-0.1
Diff in mean of infusions in LGA sessions0.20.31.1-0.70.5-1.10.20.2-0.4-0.5-0.60.3-0.60.5-0.60.6-0.60.2-0.6-0.5-0.60.70.60.40.30.30.2-0.3
Delay discount exponential model param0.20.21.10.1-0.60.1-0.3-0.3-0.0-0.1-0.2-0.1-0.10.11.0-1.01.0-0.21.00.1-0.20.4-0.00.00.2-0.60.2-0.1
Extinction: sum of active levers before priming0.10.20.6-0.40.3-0.4-0.1-0.10.1-0.4-0.30.6-0.50.60.5-0.40.50.60.5-0.6-0.30.70.60.80.50.30.30.1
Active lever presses in extinction session 61.51.55.8-0.60.9-1.91.31.3-0.7-0.2-0.1-0.3-0.1-0.2-2.42.4-2.40.1-2.40.20.10.1-0.3-0.3-0.52.1-0.7-1.0
Bone: final force0.30.51.9-0.50.7-1.00.60.6-0.3-0.4-0.10.7-0.30.4-1.31.3-1.3-0.1-1.4-0.4-0.00.30.20.30.00.7-0.2-0.5
Bone: final moment0.30.41.1-0.70.8-1.00.60.6-0.5-0.6-0.40.9-0.50.5-1.01.0-1.00.1-1.0-0.6-0.30.40.50.40.30.40.1-0.2
Food consumed during 24 hour testing period0.10.30.6-0.30.4-0.3-0.2-0.2-0.4-0.4-0.50.7-0.50.50.6-0.60.60.70.6-0.5-0.50.70.40.40.5-0.60.70.5
Glucose0.91.43.3-1.51.3-1.01.81.8-1.6-1.6-1.21.0-1.21.3-0.90.8-0.80.7-0.8-1.1-1.01.51.30.91.3-0.10.7-0.1
Heart weight0.30.51.1-0.91.1-0.40.80.8-0.8-0.7-0.90.7-0.70.8-0.60.5-0.60.7-0.6-0.8-0.70.71.00.30.9-0.70.50.7
Delay discount hyperbolic model param0.20.31.30.4-0.90.2-0.6-0.60.20.20.0-0.30.1-0.11.1-1.11.2-0.41.20.3-0.10.2-0.3-0.2-0.0-0.60.1-0.2
Intermittent access intake day 1-15 change0.10.51.4-0.80.9-0.11.21.2-0.6-0.7-0.30.8-0.60.5-0.70.6-0.71.1-0.7-0.8-0.20.60.70.80.80.50.20.9
Intermittent access intake escalation0.10.82.0-1.01.0-0.41.41.4-0.8-0.9-0.51.0-0.90.8-0.50.5-0.51.3-0.6-1.0-0.30.90.91.11.10.60.30.6
Intermittent access intake escalation 20.50.93.6-0.60.9-0.81.91.9-0.7-0.70.20.6-0.30.3-1.31.3-1.31.0-1.3-0.50.50.60.40.20.51.6-0.30.9
Intermitt. access day 1 inactive lever presses0.11.22.61.6-1.31.5-1.4-1.41.51.41.5-1.01.4-1.10.6-0.60.6-0.80.50.91.4-0.8-1.0-1.1-1.00.2-0.70.3
Intermitt. access day 15 inactive lever presses0.20.92.91.0-0.41.7-1.2-1.21.01.00.6-0.00.6-0.81.4-1.41.40.21.40.10.5-0.7-0.4-0.8-0.3-1.0-0.01.6
Intermitt. access escalation Index0.41.13.80.7-0.4-0.5-0.6-0.60.90.50.8-1.20.9-0.3-1.91.8-1.9-1.3-2.00.80.8-0.8-0.5-0.9-1.01.1-1.0-0.9
Intermittent access day 1 total infusions0.10.41.6-0.90.9-1.30.50.5-0.9-0.8-1.00.6-0.80.9-0.40.4-0.40.5-0.3-0.5-0.90.10.20.40.2-0.10.6-0.2
Intermittent access day 15 total infusions1.53.67.1-2.72.5-2.12.12.1-2.3-2.3-2.22.1-2.32.3-1.31.2-1.22.2-1.1-2.0-2.01.61.72.11.80.11.40.5
Intermittent access terminal intake (last 3 days)2.34.17.7-2.82.6-2.52.72.7-2.8-2.3-2.32.1-2.32.1-1.71.6-1.62.2-1.5-1.9-2.01.61.61.71.70.31.30.3
Intermittent access total infusions2.93.46.7-2.62.4-2.41.91.9-2.3-2.2-2.32.0-2.22.2-1.31.3-1.31.9-1.1-1.9-2.11.51.61.81.6-0.01.50.2
Intermittent access day 1 locomotion0.40.81.6-1.21.2-1.11.31.3-1.1-1.0-0.80.9-0.90.9-0.90.9-0.90.8-0.8-0.9-0.70.30.70.90.70.20.30.3
Intermittent access day 15 total locomotion0.62.35.0-2.02.1-1.62.22.2-1.9-1.5-1.51.5-1.61.1-1.51.5-1.51.7-1.4-1.4-1.21.01.11.41.10.60.80.3
Intermittent access total locomotion1.92.34.0-2.01.8-1.82.02.0-1.7-1.8-1.41.4-1.61.5-1.61.6-1.61.3-1.6-1.5-1.21.11.31.71.20.70.70.1
Intermittent access standard deviation0.10.52.1-0.60.9-0.50.10.1-0.1-0.9-0.40.8-0.61.3-0.30.3-0.31.2-0.3-0.9-0.30.60.80.50.80.00.61.5
Left kidney weight0.53.77.82.4-2.82.5-1.2-1.21.82.22.1-2.22.3-2.30.6-0.60.6-2.50.42.32.0-2.5-2.4-2.2-2.10.0-2.0-0.4
Right kidney weight0.74.610.62.7-3.13.3-1.9-1.92.12.42.1-2.32.3-2.31.6-1.71.6-2.41.42.41.9-2.6-2.4-2.1-2.0-0.7-1.6-0.4
Cocaine induced anxiety0.20.53.50.3-0.50.8-1.0-1.0-0.20.8-0.5-0.60.1-0.80.6-0.60.6-0.70.60.5-0.6-0.3-0.4-0.5-0.4-1.90.1-0.6
Post-drug Anxiety1.51.74.61.5-1.31.6-2.1-2.11.11.60.6-1.11.1-1.11.4-1.51.4-1.21.41.00.4-0.9-0.9-1.5-0.9-1.8-0.30.1
Baseline Anxiety0.50.85.20.5-0.00.9-1.2-1.21.4-0.10.60.60.20.81.1-1.11.10.51.0-0.60.50.30.60.10.5-0.10.42.3
Tail length0.21.02.01.0-0.4-0.3-0.6-0.60.81.10.9-1.21.1-1.3-1.01.0-1.0-1.0-1.01.00.9-1.1-1.3-1.4-1.30.8-1.00.2
Length with tail0.21.04.40.00.6-1.30.50.5-0.10.20.2-0.50.5-0.5-2.12.1-2.1-0.3-2.10.40.4-0.7-0.6-1.2-0.80.9-0.80.1
Length without tail0.31.64.8-1.41.8-1.71.21.2-1.0-1.1-1.00.8-0.91.1-2.22.1-2.11.0-2.1-0.9-0.80.40.90.40.60.40.20.1
Times rat made contact with spout0.50.61.70.7-0.3-0.4-0.3-0.30.50.80.6-0.90.8-1.1-0.60.6-0.6-0.6-0.60.90.6-1.3-1.2-1.0-1.20.6-0.8-0.1
Lifetime Intake1.92.44.9-2.22.0-1.91.61.6-2.0-1.8-2.01.6-1.91.9-0.90.9-0.91.6-0.8-1.6-1.81.11.31.61.3-0.11.2-0.1
Liver weight, left0.30.51.70.7-1.00.4-0.1-0.10.60.30.9-0.90.9-0.4-0.80.8-0.8-1.3-0.90.70.9-0.3-0.5-0.8-0.60.7-0.9-0.7
Liver weight, right0.71.33.31.1-1.20.3-0.1-0.10.71.31.1-1.01.3-1.5-0.70.7-0.7-1.8-0.71.31.2-1.5-1.5-1.5-1.40.9-1.5-1.3
Locomotor activity0.50.82.51.0-0.4-0.5-1.6-1.61.01.00.4-0.90.9-0.8-0.10.1-0.1-1.1-0.01.00.3-1.1-1.0-1.6-1.2-0.2-0.4-0.3
Locomotor testing distance0.51.23.31.1-0.4-0.9-1.4-1.41.21.10.8-1.21.2-1.0-0.80.9-0.8-1.3-0.81.10.7-1.3-1.2-1.8-1.50.5-0.8-0.6
Locomotor testing rearing0.31.24.1-0.31.1-0.6-2.0-2.00.4-0.3-1.11.0-0.61.00.8-0.80.81.11.0-0.9-1.30.60.8-0.10.4-2.01.51.3
Locomotion in novel chamber2.63.512.40.8-0.1-1.70.00.00.60.71.2-1.51.4-0.8-3.43.4-3.5-1.6-3.51.51.4-1.1-1.5-1.7-1.82.6-1.7-1.4
Locomotion in novel chamber post-restriction2.67.915.43.2-3.61.9-0.6-0.62.72.53.8-3.93.4-2.3-1.41.4-1.5-3.9-1.73.33.8-3.1-2.7-2.1-2.83.1-3.5-2.8
Fecal boli incidents, locomotor time 10.20.61.70.8-0.6-0.5-0.4-0.40.51.10.6-0.90.8-1.3-0.20.2-0.2-1.0-0.21.00.5-0.8-1.2-1.0-1.20.6-0.8-0.9
Change in fecal boli incidents, locomotor task0.20.21.1-0.60.40.30.20.2-0.1-0.7-0.40.5-0.60.8-0.30.3-0.30.4-0.3-0.5-0.4-0.00.51.10.6-0.20.40.1
Time >=10cm from walls, locomotor time 12.02.59.71.7-2.03.1-1.9-1.91.81.51.3-1.11.2-1.32.0-2.12.0-1.31.91.21.0-1.6-1.2-0.5-1.0-1.2-0.8-0.2
Bouts of movement, locomotor time 10.40.52.6-0.80.9-1.60.40.4-0.5-0.7-0.70.6-0.70.8-0.20.2-0.20.4-0.0-0.8-0.61.20.90.60.70.60.60.2
Total resting periods, locomotor time 10.91.04.2-1.21.3-2.10.80.8-0.9-1.1-1.01.0-1.11.1-0.20.3-0.20.7-0.0-1.1-0.91.81.30.81.10.60.90.4
Rest time, locomotor task time 10.81.25.3-1.51.1-1.02.32.3-1.9-1.2-1.10.7-1.10.6-0.80.8-0.80.3-0.8-0.8-0.91.20.80.70.90.20.3-0.2
Distance moved, locomotor task time 10.82.37.21.8-1.62.0-2.7-2.72.31.41.4-0.71.2-0.52.2-2.12.1-0.22.10.61.0-0.5-0.6-0.3-0.6-0.4-0.10.4
Vertical activity count, locomotor time 10.11.03.30.7-1.01.4-1.5-1.51.00.20.4-0.00.20.41.8-1.81.80.21.8-0.10.10.40.30.50.3-0.80.60.2
Time >=10cm from walls, locomotor time 20.41.14.91.0-1.12.2-1.2-1.20.91.10.5-0.80.7-1.01.3-1.31.3-0.91.20.80.3-1.3-0.9-0.7-0.8-1.5-0.40.4
Bouts of movement, locomotor time 20.20.61.80.40.4-0.8-0.9-0.90.60.60.3-0.30.6-0.7-1.31.3-1.3-0.1-1.30.40.4-0.4-0.6-1.0-1.00.7-0.6-0.1
Total resting periods, locomotor time 20.20.82.10.60.2-0.8-1.1-1.10.80.80.5-0.50.7-0.8-1.41.4-1.4-0.4-1.40.60.6-0.5-0.7-1.2-1.10.8-0.7-0.1
Rest time, locomotor task time 20.30.40.9-0.81.0-0.70.70.7-0.4-0.7-0.50.7-0.60.6-1.00.9-0.90.3-1.0-0.7-0.40.50.60.30.50.40.20.7
Distance moved, locomotor task time 20.81.03.11.2-1.41.2-1.2-1.21.20.81.1-0.80.8-0.31.8-1.71.7-0.41.70.60.9-0.1-0.4-0.1-0.20.1-0.1-0.2
Vertical activity count, locomotor time 20.10.31.10.8-1.00.4-0.1-0.10.50.51.0-0.90.8-0.30.1-0.10.1-0.60.00.61.00.2-0.3-0.4-0.30.8-0.5-0.7
Light reinforcement 10.10.30.50.7-0.50.6-0.6-0.60.50.40.5-0.60.5-0.20.6-0.60.6-0.60.60.50.4-0.5-0.5-0.6-0.4-0.2-0.3-0.4
Light reinforcement 20.10.11.00.1-0.4-0.0-0.1-0.10.20.30.2-0.40.1-0.20.1-0.10.1-0.30.10.30.1-0.7-0.30.4-0.30.3-0.4-1.0
Bone: marrow area0.41.03.2-0.91.3-1.80.20.2-0.3-0.7-0.71.3-0.80.9-1.51.5-1.50.7-1.5-1.1-0.60.90.90.50.50.40.30.4
Bone: maximum diameter0.10.20.90.40.1-0.2-0.9-0.91.00.40.60.40.30.0-0.30.3-0.3-0.0-0.3-0.30.60.2-0.0-0.4-0.20.6-0.30.7
Bone: maximum force0.40.92.0-0.91.2-1.40.80.8-0.6-0.9-0.41.2-0.70.9-1.31.3-1.20.4-1.2-1.1-0.31.11.00.60.70.80.30.4
Bone: maximum moment0.50.92.1-1.11.3-1.50.70.7-0.7-1.0-0.71.4-0.91.1-1.01.0-0.90.6-0.9-1.2-0.61.21.10.70.90.50.50.7
Mean time between licks in bursts0.00.31.30.1-0.30.70.30.3-0.20.0-0.0-0.1-0.0-0.11.1-1.11.10.11.10.0-0.00.2-0.10.10.3-0.40.20.6
Mean num. licks in bursts0.10.41.6-0.20.5-1.30.60.6-0.2-0.20.1-0.00.10.0-1.11.1-1.1-0.0-1.00.10.2-0.4-0.10.0-0.21.1-0.30.2
Cd content in liver0.10.10.60.2-0.3-0.20.20.2-0.10.30.1-0.40.3-0.5-0.00.0-0.0-0.4-0.00.40.2-0.8-0.5-0.5-0.50.0-0.40.0
Co content in liver0.10.10.4-0.40.20.10.60.6-0.6-0.3-0.30.6-0.40.20.2-0.20.20.50.2-0.3-0.20.50.10.30.3-0.20.30.2
Cu content in liver1.41.66.9-1.42.0-2.60.90.9-0.8-1.1-1.01.2-1.01.2-1.81.9-1.81.1-1.7-1.1-0.80.70.90.50.70.90.50.4
Fe content in liver0.70.93.7-1.11.0-1.11.91.9-1.5-1.2-0.70.8-0.80.7-0.80.9-0.80.7-0.8-0.5-0.50.30.40.90.60.70.4-0.1
K content in liver0.60.61.71.1-0.50.2-0.9-0.91.11.01.1-0.51.0-0.8-0.40.4-0.4-0.4-0.50.61.1-0.6-0.6-1.3-0.70.6-0.90.5
Mg content in liver0.10.10.7-0.10.6-0.3-0.3-0.30.3-0.1-0.00.6-0.10.3-0.10.1-0.10.8-0.1-0.50.00.50.5-0.00.40.00.20.9
Mn content in liver0.30.41.20.4-0.41.0-0.7-0.70.50.40.10.00.1-0.11.1-1.11.10.31.00.00.0-0.5-0.2-0.0-0.0-0.90.10.8
Na content in liver0.10.10.60.00.5-0.4-0.8-0.80.2-0.1-0.30.1-0.10.2-0.10.0-0.00.6-0.0-0.2-0.30.10.1-0.2-0.1-0.60.50.4
Rb content in liver0.20.31.1-0.20.30.1-0.4-0.40.1-0.1-0.30.5-0.30.30.8-0.80.81.00.9-0.3-0.40.00.10.20.2-0.70.61.0
Se content in liver0.80.92.6-0.80.7-1.11.31.3-0.5-1.1-0.10.4-0.41.1-1.61.6-1.60.2-1.6-0.60.10.80.80.70.71.5-0.1-0.0
Sr content in liver0.60.51.11.0-1.00.9-0.9-0.90.80.70.8-0.80.9-0.60.3-0.30.3-0.90.30.80.7-0.1-0.6-0.9-0.6-0.0-0.4-0.7
Zn content in liver0.80.93.70.40.2-1.20.00.00.70.40.8-0.00.6-0.2-1.81.8-1.8-0.5-1.90.21.00.1-0.2-0.8-0.41.9-0.9-0.1
Bone: minimum diameter0.81.64.4-1.41.4-1.11.11.1-0.8-1.6-0.71.8-1.21.7-0.60.6-0.61.0-0.5-1.8-0.62.11.71.41.60.60.91.4
Time in familiar zone, hab. session 10.10.10.50.20.1-0.7-0.5-0.50.20.3-0.1-0.50.2-0.2-0.10.2-0.1-0.3-0.00.4-0.1-0.3-0.3-0.7-0.3-0.1-0.0-0.3
Time in novel zone, hab. session 10.00.00.20.0-0.50.50.20.2-0.1-0.10.1-0.00.00.10.1-0.10.1-0.40.00.00.10.10.10.30.10.1-0.1-0.4
Total zone transitions, hab. session 10.20.31.40.20.1-0.4-1.2-1.20.00.7-0.4-0.40.2-0.6-0.10.0-0.0-0.40.00.5-0.5-0.7-0.5-0.9-0.7-1.1-0.0-0.6
Total locomotion distance, hab. session 10.20.31.4-0.50.9-1.0-0.4-0.4-0.7-0.0-1.10.1-0.50.0-0.10.1-0.10.40.1-0.2-1.1-0.00.2-0.30.1-1.20.6-0.2
Locomotion velocity, hab. session 10.10.20.9-0.30.6-0.7-0.4-0.4-0.50.2-0.8-0.1-0.3-0.2-0.20.1-0.10.3-0.0-0.0-0.8-0.2-0.1-0.4-0.1-1.00.3-0.2
Time in familiar zone, hab. session 20.30.32.9-0.20.8-1.70.30.3-0.4-0.1-0.4-0.2-0.0-0.0-0.80.8-0.70.4-0.60.2-0.3-0.6-0.4-0.7-0.50.20.20.7
Time in novel zone, hab. session 20.40.42.80.6-1.11.7-0.5-0.50.70.40.7-0.30.4-0.20.7-0.70.7-0.70.50.20.60.30.10.50.10.1-0.5-0.9
Total zone transitions, hab. session 21.52.04.51.4-0.8-0.6-1.5-1.51.11.71.0-1.71.5-1.6-1.31.2-1.2-1.4-1.31.70.9-1.7-1.6-2.1-1.90.5-1.3-0.9
Total locomotion distance, hab. session 22.12.75.51.4-0.4-1.4-1.8-1.81.31.91.0-2.11.7-1.8-1.61.6-1.6-1.4-1.61.91.0-2.2-1.9-2.4-2.31.0-1.5-1.0
Locomotion velocity, hab. session 21.72.24.51.3-0.4-1.1-1.6-1.61.21.80.9-1.91.5-1.6-1.51.5-1.5-1.2-1.51.70.9-2.1-1.8-2.1-2.10.8-1.4-0.9
Novel to familiar place preference ratio0.20.31.1-0.1-0.40.80.20.2-0.3-0.5-0.10.5-0.30.61.0-1.01.00.31.0-0.3-0.10.60.30.50.5-0.40.50.1
Novelty place preference0.10.20.5-0.1-0.40.60.40.4-0.3-0.40.00.3-0.10.40.7-0.70.70.10.7-0.10.00.50.20.30.4-0.10.3-0.0
Time in novel zone, NPP test0.30.41.0-0.3-0.20.60.50.5-0.6-0.7-0.30.6-0.50.71.0-1.01.00.31.0-0.4-0.30.90.50.60.8-0.40.60.2
Total zone transitions, NPP test1.82.65.61.7-1.60.2-1.0-1.01.12.01.5-2.41.9-2.1-0.80.8-0.8-2.0-0.82.21.5-2.2-2.1-2.0-2.11.0-1.8-1.2
Total locomotion distance, NPP test0.60.82.40.7-0.6-0.4-0.1-0.10.11.00.6-1.50.9-1.3-0.50.6-0.5-1.1-0.51.30.6-1.3-1.3-1.2-1.20.5-1.0-1.0
Locomotion velocity, NPP test1.01.53.61.2-1.0-0.0-0.4-0.40.51.51.0-1.91.3-1.7-0.60.6-0.6-1.3-0.61.71.0-1.8-1.8-1.6-1.60.7-1.4-1.2
Intraocular pressure0.30.51.80.30.0-0.20.40.40.20.30.5-0.60.5-0.6-1.31.2-1.3-0.3-1.30.50.6-0.9-0.6-0.4-0.81.0-0.8-0.3
Delta distance traveled before/after self-admin3.13.48.8-2.31.70.41.01.0-1.6-2.4-2.21.9-2.42.70.4-0.40.42.20.4-2.1-2.31.62.33.02.3-1.92.10.9
Delta ambulatory time before/after self-admin1.22.15.5-1.61.01.10.80.8-1.3-1.8-1.61.3-1.72.00.8-0.80.81.60.7-1.5-1.61.11.72.31.8-1.91.60.7
Parametrial fat weight0.71.75.90.40.4-1.7-0.2-0.20.80.70.9-0.50.9-0.7-2.42.4-2.4-0.6-2.40.71.0-0.9-0.8-1.0-1.32.3-1.2-0.8
Pavlov. Cond. lever latency0.30.31.2-0.30.20.10.40.4-0.9-0.4-0.70.1-0.30.00.9-0.90.90.41.0-0.1-0.60.50.1-0.40.3-1.10.70.0
Pavlov. Cond. magazine entry latency1.82.44.31.9-1.40.1-1.5-1.52.11.82.0-1.51.9-1.5-1.01.0-1.0-1.6-1.11.61.9-1.5-1.4-1.6-1.71.8-1.8-0.7
Pavlov. Cond. change in total contacts1.11.23.30.8-0.7-0.4-0.5-0.51.20.81.2-1.01.0-0.5-1.61.6-1.6-1.4-1.70.81.2-0.9-0.5-0.4-0.91.8-1.4-1.0
Pavlov. Cond. index score0.60.71.50.8-0.6-0.1-0.7-0.71.20.91.1-0.70.9-0.6-0.90.9-0.9-0.8-0.90.71.0-1.0-0.6-0.4-0.81.2-1.1-0.3
Pavlov. Cond. latency score0.70.81.90.9-0.7-0.0-0.7-0.71.31.01.2-0.81.0-0.7-0.90.9-0.9-0.9-1.00.81.2-1.0-0.7-0.5-0.91.4-1.2-0.3
Pavlov. Cond. lever contacts0.40.52.00.4-0.3-0.2-0.4-0.41.00.40.8-0.40.5-0.0-1.21.2-1.2-0.6-1.30.30.8-0.7-0.20.2-0.51.4-0.9-0.2
Pavlov. Cond. magazine entry number1.11.43.2-1.51.2-0.31.21.2-1.8-1.4-1.71.2-1.51.00.7-0.70.71.20.8-1.1-1.61.10.90.91.2-1.41.40.5
Pavlov. Cond. intertrial magazine entries1.62.05.7-1.72.4-1.8-0.0-0.0-0.8-1.4-1.62.2-1.61.5-0.60.6-0.61.9-0.5-1.9-1.51.51.61.11.3-0.51.51.4
Pavlov. Cond. lever-magazine prob. diff.0.91.12.21.1-0.8-0.0-0.9-0.91.41.11.3-1.01.1-0.8-1.11.1-1.1-1.0-1.10.91.3-1.2-0.8-0.5-1.11.5-1.3-0.5
Pavlov. Cond. response bias1.31.63.51.5-1.30.4-1.2-1.21.91.41.8-1.31.5-1.0-0.90.9-0.9-1.4-1.01.21.7-1.3-1.0-0.8-1.31.6-1.6-0.6
Pavlov. Cond. lever latency0.20.31.1-0.60.8-1.10.30.3-0.5-0.5-0.60.2-0.40.5-0.90.8-0.80.3-0.8-0.4-0.50.70.6-0.00.30.00.3-0.3
Pavlov. Cond. magazine entry latency0.81.23.61.1-0.60.2-0.5-0.51.31.11.6-0.81.3-1.0-1.11.1-1.1-0.8-1.20.81.6-0.9-0.9-0.9-1.11.9-1.50.1
Pavlov. Cond. change in total contacts0.92.34.22.0-2.01.9-1.2-1.21.71.82.0-1.51.8-1.70.7-0.60.6-1.50.51.61.9-1.7-1.9-1.2-1.70.7-1.5-0.6
Pavlov. Cond. index score0.50.82.11.2-1.00.7-0.6-0.61.31.11.4-0.81.1-0.9-0.10.1-0.1-0.8-0.20.81.4-1.0-1.0-0.6-0.91.2-1.1-0.1
Pavlov. Cond. latency score0.81.22.91.4-1.10.6-0.6-0.61.41.31.7-0.91.4-1.2-0.40.4-0.5-1.1-0.61.11.7-1.2-1.2-0.8-1.21.6-1.5-0.2
Pavlov. Cond. lever contacts0.30.51.80.8-1.01.3-0.4-0.40.70.60.7-0.30.5-0.61.1-1.11.1-0.31.00.50.6-0.8-0.7-0.1-0.4-0.1-0.30.3
Pavlov. Cond. magazine entry number2.02.65.3-1.81.1-0.11.21.2-2.1-1.8-2.21.4-2.01.61.4-1.41.41.41.5-1.4-2.21.51.51.61.8-2.32.00.2
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.30.5-0.5-0.6-0.60.3-0.5-0.50.1-0.40.9-0.10.1-0.10.3-0.1-0.4-0.60.40.80.40.5-0.40.6-0.0
Pavlov. Cond. lever-magazine prob. diff.0.71.12.61.4-1.20.8-0.8-0.81.41.21.6-1.01.3-1.1-0.10.1-0.2-1.0-0.31.01.6-1.1-1.1-0.6-1.11.3-1.3-0.3
Pavlov. Cond. response bias0.40.51.10.9-0.91.1-0.6-0.60.80.90.9-0.50.7-0.80.7-0.70.7-0.30.60.60.8-0.9-0.9-0.3-0.70.2-0.60.3
Time in closed arm before self-admin0.10.10.8-0.1-0.00.60.20.2-0.40.1-0.3-0.4-0.0-0.3-0.20.1-0.2-0.0-0.20.3-0.3-0.5-0.3-0.0-0.3-0.90.1-0.8
Time in closed arm after self-admin0.10.10.50.1-0.4-0.10.70.7-0.40.20.0-0.20.1-0.50.4-0.40.4-0.30.50.20.10.3-0.3-0.4-0.10.1-0.2-0.7
Time in open arm before self-admin0.10.11.2-0.00.0-0.70.20.20.1-0.20.20.4-0.10.20.4-0.30.40.30.4-0.30.20.50.30.40.31.10.10.6
Time in open arm after self-admin0.40.51.8-0.50.9-0.90.10.1-0.1-0.6-0.20.4-0.20.7-1.31.3-1.30.5-1.3-0.4-0.10.50.50.10.30.80.10.7
Bone: periosteal estimation0.20.51.7-0.60.9-0.9-0.3-0.30.1-0.6-0.31.3-0.60.9-0.50.5-0.50.6-0.5-1.2-0.31.20.90.50.70.30.50.9
Bone: periosteal perimeter0.20.31.80.20.00.1-1.4-1.41.0-0.00.20.7-0.10.70.4-0.40.40.10.4-0.70.10.70.50.30.4-0.00.40.8
Bone: post-yield work0.50.93.70.5-1.01.9-0.5-0.50.50.20.40.10.10.11.9-1.91.9-0.11.7-0.40.30.90.40.40.7-0.80.20.6
Progressive ratio test 1 active lever presses0.61.12.5-1.51.2-0.80.40.4-1.2-1.1-1.61.2-1.51.2-0.10.1-0.10.90.0-1.2-1.60.91.11.41.0-0.91.0-0.1
Progressive ratio test 1 breakpoint0.61.12.4-1.51.1-0.70.40.4-1.2-1.1-1.51.2-1.41.3-0.0-0.00.00.90.1-1.3-1.51.01.21.41.1-0.91.0-0.1
Progressive ratio test 1 inactive lever presses0.00.10.20.10.2-0.3-0.3-0.30.30.40.00.00.1-0.3-0.40.4-0.4-0.1-0.4-0.10.0-0.30.0-0.2-0.20.3-0.3-0.0
Progressive ratio test 2 active lever presses2.94.27.7-2.82.6-2.72.12.1-2.6-2.5-2.52.0-2.32.4-1.71.7-1.71.9-1.5-2.0-2.21.91.81.71.8-0.11.60.0
Progressive ratio test 2 breakpoint3.44.48.0-2.82.7-2.82.22.2-2.7-2.5-2.52.1-2.42.5-1.81.7-1.72.0-1.6-2.0-2.22.01.91.71.8-0.01.60.1
Progressive ratio test 2 inactive lever presses0.30.92.3-1.41.5-1.30.70.7-1.2-0.8-1.31.2-1.20.6-0.90.9-0.91.2-0.8-1.0-1.20.50.70.60.7-0.20.60.5
Incentive Sensitization - Responses1.02.96.4-2.12.1-2.52.02.0-2.2-2.0-1.81.4-1.61.7-2.12.0-2.01.5-1.9-1.3-1.51.31.11.01.10.51.0-0.2
Incentive Sensitization - Breakpoint1.33.05.9-2.22.2-2.42.22.2-2.3-2.0-1.81.4-1.71.7-2.02.0-2.01.6-1.9-1.3-1.51.21.11.11.10.61.0-0.2
Sum of active levers in priming session hrs 5-60.10.10.40.0-0.20.40.10.10.40.10.3-0.0-0.0-0.10.1-0.10.10.10.10.10.2-0.7-0.10.5-0.00.3-0.4-0.2
Progressive ratio0.10.30.9-0.50.30.20.70.7-0.8-0.3-0.70.3-0.5-0.10.6-0.60.60.40.6-0.3-0.60.00.2-0.00.4-1.00.30.5
Food seeking constrained by brief footshock1.51.93.4-1.61.8-1.61.21.2-0.9-1.4-1.11.4-1.41.7-1.51.4-1.41.5-1.4-1.6-0.91.51.71.41.50.60.70.7
Seeking ratio, punishment vs. effort0.30.62.0-0.50.7-1.30.30.30.1-0.50.00.4-0.30.7-1.41.4-1.40.3-1.4-0.50.10.70.60.70.41.40.0-0.4
Retroperitoneal fat weight0.10.31.1-0.00.6-1.1-0.4-0.40.50.20.10.00.1-0.3-1.01.0-1.00.1-1.00.20.1-0.8-0.3-0.2-0.60.8-0.20.4
Reaction time number correct0.41.33.0-1.51.7-1.40.90.9-1.0-1.2-1.21.3-1.21.1-1.31.3-1.30.9-1.2-1.5-1.01.11.40.61.0-0.10.70.7
Reaction time mean minus median0.10.41.5-0.30.40.3-0.2-0.20.2-0.5-0.00.5-0.31.2-0.40.4-0.40.7-0.5-0.8-0.11.21.10.80.90.30.40.8
Reaction time mean minus median AUC0.10.61.7-0.30.5-0.5-0.2-0.20.3-0.60.10.2-0.21.2-1.21.2-1.20.5-1.3-0.70.11.11.10.70.70.90.20.7
Reaction time num false alarms0.20.32.0-0.30.2-0.71.41.4-1.1-0.3-0.3-0.2-0.1-0.3-0.20.2-0.2-0.1-0.10.2-0.10.4-0.3-0.70.00.1-0.1-0.9
Reaction time num false alarms AUC0.20.52.10.3-0.3-0.60.90.9-0.50.30.3-0.80.5-0.8-0.50.5-0.5-0.8-0.50.70.5-0.1-0.8-1.2-0.60.7-0.7-1.5
Reaction time trials correct on left0.41.33.0-1.51.7-1.40.90.9-1.0-1.2-1.21.3-1.21.1-1.31.3-1.30.9-1.2-1.5-1.01.11.40.61.0-0.10.70.7
Reaction time trials on left0.41.22.8-1.41.7-1.50.80.8-0.9-1.1-1.11.2-1.01.0-1.41.4-1.40.7-1.3-1.4-0.91.11.30.50.9-0.00.60.6
Reaction time mean0.20.51.50.3-0.2-0.7-1.1-1.11.00.10.5-0.50.30.4-0.90.9-0.9-0.4-1.00.20.30.30.30.4-0.21.1-0.2-1.2
Reaction time mean AUC0.30.61.90.3-0.1-1.0-1.0-1.01.00.10.5-0.60.40.5-1.31.3-1.3-0.4-1.30.20.40.50.40.3-0.21.4-0.3-1.2
Median of all reaction times0.40.63.40.5-0.4-0.8-1.0-1.01.00.30.6-0.80.50.1-0.90.9-0.9-0.7-0.90.50.4-0.1-0.10.3-0.51.2-0.4-1.8
Reaction time omissions1.93.15.52.0-1.5-0.5-1.2-1.21.81.82.1-2.32.2-1.3-1.91.9-1.9-2.0-2.01.82.1-1.1-1.4-2.0-1.72.2-2.0-0.8
Reaction time false alarm rate0.71.02.61.1-1.40.50.20.20.20.90.9-1.41.1-1.20.7-0.60.7-1.20.61.41.0-0.7-1.4-1.2-0.90.4-0.9-1.6
Reaction time premature initiation rate0.40.63.10.5-0.70.8-0.5-0.50.20.50.2-0.20.1-0.61.7-1.71.70.11.80.40.0-0.5-0.60.1-0.3-0.60.20.1
Reaction time premature initiations0.10.31.2-0.20.10.1-0.2-0.2-0.20.0-0.40.5-0.4-0.11.0-1.01.00.51.1-0.4-0.50.10.10.20.1-0.70.50.4
Std. dev. reaction times0.30.82.21.1-1.00.4-0.8-0.81.30.81.3-1.31.1-0.3-0.80.8-0.8-1.0-1.00.81.2-0.2-0.3-0.3-0.61.5-1.0-0.8
Reaction time trials completed0.41.22.8-1.41.7-1.50.80.8-0.9-1.1-1.11.2-1.01.0-1.41.4-1.40.7-1.3-1.4-0.91.11.30.50.9-0.00.60.6
Reaction time trials AUC0.41.32.8-1.31.7-1.50.90.9-0.9-1.1-1.01.2-1.01.0-1.61.6-1.60.7-1.5-1.3-0.81.01.30.40.80.10.40.5
Run reversals in cocaine runway, females3.23.65.61.7-0.9-0.3-0.8-0.81.41.91.9-1.92.1-2.4-2.22.2-2.2-1.8-2.32.02.0-2.0-2.1-2.1-2.42.1-2.3-1.5
Run reversals in cocaine runway, males1.41.54.21.1-0.8-1.1-0.7-0.70.51.10.9-1.61.3-1.1-1.21.2-1.2-1.5-1.21.51.0-0.7-1.4-2.1-1.61.1-1.1-1.7
Latency to leave start box in cocaine runway0.50.73.00.7-0.80.6-1.7-1.70.70.70.1-0.30.4-0.41.1-1.11.1-0.41.20.4-0.1-0.4-0.4-0.8-0.4-1.30.10.1
Latency to leave start box in cocaine runway, F0.50.62.90.2-0.60.6-0.8-0.80.10.3-0.30.1-0.1-0.21.6-1.61.60.11.70.0-0.4-0.2-0.1-0.10.1-1.50.40.3
Latency to leave start box in cocaine runway, M0.30.22.50.40.10.0-1.6-1.60.60.30.00.00.20.1-0.00.0-0.0-0.2-0.00.1-0.10.0-0.0-0.4-0.3-0.40.00.1
Std. dev. time between licks in bursts0.51.02.91.3-1.70.9-0.1-0.10.71.11.3-1.41.2-1.10.3-0.30.3-1.40.21.31.4-0.6-1.1-1.0-0.80.9-1.2-0.1
Total sessions with >9 infusions0.50.72.3-1.00.7-0.10.10.1-0.5-0.8-1.01.1-1.11.50.5-0.50.50.80.6-1.0-1.10.31.01.31.0-0.70.80.1
Short access day 1 total inactive lever presses0.30.72.40.4-0.40.8-1.5-1.50.50.5-0.2-0.30.1-0.51.3-1.31.3-0.01.30.3-0.4-0.6-0.3-0.2-0.3-1.50.30.2
Short access day 10 total inactive lever presses0.42.95.52.3-1.72.1-2.1-2.12.22.21.9-1.52.0-2.21.1-1.11.0-0.91.01.51.8-2.1-1.8-2.0-1.7-0.4-1.20.8
Short access day 1 total infusions0.10.31.1-0.60.5-0.9-0.1-0.1-0.4-0.5-0.80.2-0.60.8-0.00.00.00.30.1-0.4-0.90.10.50.60.3-0.10.5-1.0
Short access day 10 total infusions1.62.64.7-2.22.1-1.61.71.7-2.0-2.0-1.81.6-1.72.1-1.71.6-1.61.3-1.6-1.6-1.61.21.41.31.4-0.01.10.4
Short access total infusions0.60.81.8-1.31.3-1.10.50.5-0.9-0.9-1.31.0-1.21.2-0.60.6-0.60.9-0.5-1.0-1.30.20.91.10.7-0.20.7-0.3
Short access day 1 locomotion0.91.43.3-1.61.4-1.01.81.8-1.4-1.4-1.01.3-1.31.6-0.70.7-0.71.2-0.7-1.3-0.90.81.21.61.20.50.7-0.1
Short access day 10 total locomotion0.20.74.1-0.30.21.10.20.20.2-0.60.11.0-0.50.91.1-1.01.00.91.0-1.10.10.30.81.11.1-0.60.52.0
Short access total locomotion0.81.34.0-1.10.90.30.00.0-0.2-1.2-0.91.5-1.31.80.7-0.70.71.30.7-1.6-1.00.51.52.01.5-1.01.11.3
One hour access (0.3 mA shock)3.84.58.8-3.02.5-2.22.62.6-2.6-2.9-2.32.2-2.62.5-1.21.2-1.12.3-1.0-2.2-2.11.92.12.72.10.11.70.5
Compulsive drug intake0.30.41.00.5-0.91.0-1.0-1.00.80.10.3-0.50.2-0.01.0-1.01.0-0.40.90.20.1-0.20.20.50.1-0.80.1-0.2
One hour access (shock baseline)1.33.56.7-2.62.3-2.12.62.6-2.3-2.2-1.82.1-2.12.0-1.31.3-1.32.1-1.2-1.8-1.51.51.52.11.61.01.10.3
Social response proportion0.40.61.90.5-0.41.0-1.2-1.20.80.40.20.10.2-0.11.4-1.41.4-0.01.40.0-0.0-0.3-0.10.1-0.1-1.00.30.5
Social responses0.60.81.61.2-0.70.5-1.2-1.21.21.31.1-0.61.1-1.20.2-0.20.2-0.60.20.81.0-1.0-1.1-1.2-1.10.6-0.80.4
Social time0.10.20.70.5-0.30.1-0.8-0.80.70.60.3-0.20.4-0.40.0-0.00.0-0.60.00.20.3-0.2-0.2-0.6-0.4-0.0-0.20.3
Soleus weight0.82.44.9-2.01.8-1.22.22.2-2.2-2.1-1.71.1-1.71.9-0.80.8-0.81.1-0.7-1.6-1.51.91.81.31.8-0.31.20.4
Bone: stiffness0.20.31.2-0.20.2-0.50.60.6-0.3-0.20.10.3-0.00.1-1.01.0-1.0-0.3-1.1-0.20.20.40.1-0.0-0.00.7-0.3-0.6
Tibialis anterior weight2.07.012.9-2.92.6-0.61.11.1-2.2-3.2-2.93.4-3.13.51.2-1.31.32.91.4-3.4-3.03.63.52.83.3-2.53.31.8
Time to tail flick, vehicle, before self-admin0.30.31.90.3-0.1-0.0-1.1-1.10.00.3-0.3-0.10.0-0.00.8-0.70.80.20.8-0.1-0.50.30.1-0.5-0.1-1.40.5-0.0
Time to tail flick, vehicle, after self-admin0.81.73.61.3-1.81.11.01.00.31.11.4-1.61.4-1.70.1-0.10.0-1.9-0.01.61.5-1.5-1.5-1.3-1.21.0-1.8-1.4
Time to tail flick, test, before self-admin0.10.21.2-0.30.6-1.1-0.1-0.1-0.2-0.2-0.3-0.0-0.2-0.2-0.60.6-0.60.6-0.6-0.2-0.30.1-0.0-0.0-0.20.40.3-0.0
Time to tail flick, test, after self-admin0.60.61.80.7-0.6-0.40.10.10.50.81.0-0.90.8-1.1-0.50.6-0.6-0.9-0.60.91.0-0.9-1.0-0.7-1.01.4-1.0-0.7
Delta time to tail flick, vehicle, before/after SA1.92.03.91.6-1.81.1-0.1-0.11.31.51.8-1.61.6-1.8-0.10.1-0.1-2.0-0.21.81.8-1.8-1.8-1.2-1.61.6-1.9-1.0
Delta time to tail flick, test, before/after SA0.30.41.30.7-0.80.2-0.4-0.40.60.80.7-0.70.8-0.6-0.30.3-0.3-1.2-0.30.80.7-0.7-0.7-0.8-0.70.4-0.8-0.7
Tibia length0.41.23.31.2-0.8-0.3-1.8-1.81.71.41.0-1.11.1-0.9-0.60.6-0.6-1.2-0.60.90.9-1.1-0.9-1.0-1.20.7-1.0-0.9
Ambulatory time before self-admin0.30.82.91.0-0.5-1.4-0.5-0.50.80.91.0-1.01.0-0.9-0.70.7-0.7-0.7-0.60.81.0-0.5-0.9-1.3-1.01.7-0.9-0.6
Ambulatory time after self-admin0.20.31.4-0.40.4-0.30.40.40.1-0.7-0.00.1-0.40.9-0.50.5-0.50.7-0.6-0.4-0.10.30.61.20.50.70.2-0.0
Bone: tissue strength0.50.53.0-0.41.3-1.7-1.0-1.00.2-0.2-0.60.7-0.30.5-0.50.5-0.50.8-0.3-0.6-0.60.40.6-0.50.2-0.40.71.3
Total heroin consumption0.40.41.00.6-1.00.50.00.00.80.60.9-0.80.5-0.70.3-0.20.3-0.60.20.70.9-0.9-0.70.2-0.61.0-1.0-0.5
Bone: trabecular number0.20.42.80.60.1-0.3-1.7-1.71.30.50.6-0.10.60.1-0.30.4-0.4-0.2-0.30.00.5-0.1-0.1-0.4-0.40.6-0.00.9
Bone: trabecular spacing0.71.02.3-1.10.40.31.31.3-1.5-1.2-1.21.1-1.10.80.7-0.80.80.80.8-0.8-1.11.11.00.91.2-1.31.00.4
Bone: trabecular thickness0.30.42.00.7-0.40.2-1.2-1.21.40.70.9-0.70.6-0.20.0-0.00.0-0.50.00.40.8-0.7-0.30.2-0.50.9-0.50.2
Bone: trabecular tissue density0.81.54.6-0.2-0.01.2-1.6-1.60.5-0.4-0.80.5-0.81.01.8-1.91.91.21.8-0.8-1.10.61.01.30.8-2.11.40.7
Water consumed over 24 hours0.00.10.4-0.20.5-0.40.30.3-0.3-0.0-0.30.3-0.2-0.1-0.10.1-0.10.5-0.1-0.0-0.2-0.4-0.2-0.2-0.1-0.10.10.6
Number of responses in last shaping day1.41.83.4-1.71.5-1.11.91.9-1.3-1.6-1.01.5-1.41.7-1.01.0-1.01.4-1.0-1.5-0.81.61.51.61.50.90.80.3