Hub : Genes

Mief1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Mief1 0.38 0.18 3.3e-04 0.08 0.11 0.13 0.07 6.9e-03 1.1e-03 4.6e-04 9.4e-03
2 BLA intron excision ratio chr7_113677594_113678498 0.1 0.08 6.9e-03 0.02 0.01 0.01 0.02 2.1e-02 5.7e-02 6.9e-02 3.0e-02
3 BLA gene expression Mief1 0.45 0.12 0.0e+00 0.27 0.26 0.26 0.28 1.9e-14 4.0e-14 3.2e-14 3.5e-15
4 IC gene expression Mief1 0.22 0.09 4.4e-08 0.14 0.19 0.08 0.18 2.9e-06 2.5e-08 3.9e-04 5.8e-08
5 pVTA gene expression Mief1 0.4 0.1 0.0e+00 0.45 0.3 0.42 0.44 4.3e-40 1.6e-24 5.8e-37 4.6e-38
6 Brain gene expression Mief1 0.17 0.07 4.8e-14 0.15 0.13 0.14 0.16 5.8e-14 1.7e-12 3.1e-13 1.0e-14
7 BLA mRNA stability Mief1 0.19 0.12 2.2e-03 0.04 0.02 0.02 0.04 3.0e-03 2.1e-02 2.4e-02 4.9e-03
8 pVTA intron excision ratio chr7_113677594_113678498 0.07 0.04 3.5e-04 0.05 0.04 0.04 0.05 3.6e-05 3.3e-04 2.4e-04 8.7e-05
9 LHb gene expression Mief1 0.53 0.12 6.0e-10 0.3 0.27 0.29 0.29 6.0e-08 4.4e-07 1.4e-07 1.4e-07
10 OFC gene expression Mief1 0.22 0.12 3.1e-03 0.06 0.04 0 0.03 1.7e-02 3.3e-02 2.4e-01 5.6e-02
11 Liver intron excision ratio chr7_113667092_113668615 0.03 0.03 6.0e-03 0 0.01 0.02 0.01 3.3e-01 5.6e-02 1.1e-03 7.0e-02
12 Adipose gene expression Mief1 0.05 0.03 6.4e-05 0.03 0.02 0.02 0.02 1.5e-04 1.5e-03 5.0e-03 4.9e-03
13 PL gene expression Mief1 0.4 0.11 0.0e+00 0.36 0.35 0.35 0.37 4.3e-41 7.6e-40 1.1e-39 9.5e-42
14 Adipose mRNA stability Mief1 0.04 0.03 1.5e-04 0.02 0.03 0.01 0.02 2.1e-03 5.7e-04 8.9e-03 2.4e-03
15 Liver gene expression Mief1 0.38 0.11 0.0e+00 0.32 0.35 0.37 0.15 1.8e-36 8.6e-41 8.3e-43 2.5e-16
16 NAcc mRNA stability Mief1 0.02 0.01 5.7e-03 0 0.01 0.01 0.01 1.1e-01 2.4e-03 1.5e-02 2.1e-02
17 NAcc gene expression Mief1 0.4 0.14 0.0e+00 0.24 0.26 0.28 0.27 7.0e-36 1.6e-38 7.5e-42 1.1e-40

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.20.40.7-0.7-0.9-0.5-0.5-0.4-0.6-0.6-0.7-0.7-0.70.50.0-0.6-0.4-0.7-0.6-0.3
Area under the delay curve1.61.83.7-1.9-1.0-1.9-1.6-1.5-1.7-1.3-1.3-1.3-1.31.0-0.8-1.5-0.6-1.5-1.2-0.8
BMI with tail0.31.22.01.41.01.31.41.41.11.31.21.21.20.30.91.10.01.10.70.7
BMI without tail0.00.11.20.4-0.50.30.40.00.1-0.1-0.1-0.1-0.10.61.1-0.00.00.20.2-0.1
Body weight0.83.38.52.92.22.22.22.31.82.21.91.91.9-1.70.21.8-0.61.30.80.8
Weight adjusted by age0.30.41.50.6-0.30.60.70.50.70.60.40.40.4-0.20.40.70.90.80.91.2
Bone surface0.10.20.9-0.4-0.4-0.6-0.5-0.2-0.5-0.4-0.4-0.4-0.4-0.2-0.4-0.4-0.5-1.0-0.6-0.3
Bone volume0.00.10.3-0.2-0.4-0.2-0.10.1-0.2-0.1-0.2-0.2-0.20.30.0-0.2-0.3-0.5-0.30.1
Breakpoint value in progressive ratio session0.10.10.5-0.00.3-0.2-0.3-0.2-0.4-0.2-0.2-0.2-0.2-0.3-0.4-0.4-0.7-0.5-0.6-0.7
Number of licking bursts0.40.61.4-1.1-1.2-1.0-0.7-0.9-0.8-1.0-0.9-0.9-0.90.80.4-0.80.3-0.6-0.3-0.3
Context. condit. distance diff. score6.27.511.03.22.53.33.23.13.13.13.13.13.1-0.91.43.01.22.92.42.2
Locomotion velocity, session 10.40.51.3-0.10.4-0.6-0.6-0.3-0.6-0.4-0.5-0.5-0.5-1.1-1.1-0.5-0.9-1.0-0.8-0.6
Locomotion distance, session 12.02.54.8-2.0-1.7-2.2-1.8-1.6-1.9-1.7-1.8-1.8-1.81.1-0.2-1.6-0.2-1.6-1.1-1.2
Locomotion velocity, session 20.10.10.80.10.90.20.00.20.00.20.20.20.2-0.1-0.40.1-0.5-0.2-0.30.0
Locomotion distance, session 24.36.09.5-2.8-1.7-3.1-2.9-2.6-2.9-2.6-2.7-2.6-2.60.6-1.5-2.7-1.5-2.8-2.4-2.2
Locomotion velocity, session 33.23.65.01.91.02.02.22.02.12.02.02.02.00.11.72.21.81.92.22.1
Locomotion distance, session 31.31.55.10.2-0.80.51.00.50.90.50.50.60.61.62.30.92.21.31.71.6
Stereotopy head waving bouts, day 30.50.62.10.41.2-0.0-0.20.2-0.30.00.1-0.0-0.0-1.3-1.4-0.2-1.5-0.8-0.9-0.6
Stereotopy head waving duration, day 31.21.45.71.42.41.00.61.10.61.01.00.90.9-1.9-1.50.5-1.7-0.4-0.6-0.3
Locomotion velocity, session 71.21.32.31.31.21.51.21.21.51.31.21.21.2-0.60.21.30.51.31.00.9
Locomotion distance, session 70.10.21.10.20.50.1-0.2-0.10.1-0.0-0.1-0.1-0.1-1.0-0.9-0.1-0.6-0.1-0.4-0.2
Stereotopy head waving bouts, day 74.04.56.42.52.02.52.52.52.32.32.42.42.4-0.41.32.41.11.91.92.0
Stereotopy head waving duration, day 73.44.16.12.21.82.52.42.32.22.22.32.32.30.11.52.21.22.01.91.9
Locomotion velocity, session 81.01.23.81.71.81.20.81.01.01.01.11.11.1-1.9-0.80.8-0.90.3-0.00.3
Locomotion distance, session 80.60.91.40.90.51.01.11.20.91.11.11.11.1-0.00.71.20.71.01.01.0
Degree of sensitization distance1.51.56.80.51.60.3-0.5-0.0-0.20.0-0.1-0.1-0.1-2.5-2.6-0.4-2.3-0.6-1.5-1.3
Degree of sensitization stereotypy3.43.75.22.21.62.32.32.12.12.12.12.12.1-0.11.42.11.22.01.91.9
Conditioned locomotion0.30.40.60.70.70.70.60.60.60.60.70.70.7-0.6-0.20.60.00.70.40.5
Cocaine response after cond. corrected0.20.21.1-0.00.7-0.3-0.30.1-0.40.1-0.1-0.2-0.2-0.9-1.1-0.1-0.8-0.5-0.6-0.4
Cocaine response after cond. not corrected0.10.10.5-0.10.5-0.3-0.20.1-0.30.1-0.1-0.1-0.1-0.5-0.7-0.0-0.5-0.3-0.4-0.3
Cocaine response before conditioning0.30.31.5-0.1-0.60.10.3-0.10.20.10.20.20.21.21.10.10.90.40.60.3
Saline control response0.50.61.40.7-0.20.90.90.50.90.60.60.70.7-0.00.70.81.11.21.11.0
Bone: connectivity density0.10.10.3-0.0-0.2-0.2-0.3-0.1-0.3-0.3-0.3-0.3-0.3-0.6-0.3-0.3-0.5-0.5-0.5-0.4
Bone: cortical apparent density0.91.24.60.3-0.80.61.00.30.80.50.50.50.51.62.10.61.90.91.51.4
Bone: cortical area0.30.52.30.31.20.1-0.10.4-0.10.20.30.30.3-0.8-1.4-0.1-1.5-0.6-1.0-0.3
Bone: cortical porosity0.30.31.60.50.80.60.10.50.30.50.30.30.3-1.2-1.10.3-0.80.3-0.3-0.1
Bone: cortical porosity0.91.04.11.01.70.80.20.80.40.70.60.60.6-2.0-1.80.5-1.40.2-0.6-0.3
Bone: cortical thickness0.10.20.6-0.60.1-0.4-0.5-0.2-0.6-0.3-0.3-0.3-0.30.4-0.8-0.4-0.8-0.6-0.8-0.2
Bone: cortical thickness1.01.12.0-1.1-0.0-1.3-1.2-0.8-1.3-0.9-0.9-0.9-0.90.6-1.0-1.2-1.3-1.3-1.4-1.0
Bone: cortical tissue density0.81.14.10.3-0.70.61.00.30.90.50.60.60.61.52.00.61.90.91.51.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.3-0.2-0.4-0.2-0.3-0.3-0.3-0.3-0.4-0.40.2-0.0-0.4-0.0-0.6-0.2-0.1
Condit. Reinf. active-inactive response ratio0.50.51.00.60.50.80.90.80.80.80.80.70.70.20.50.80.70.60.81.0
Condit. Reinf. active responses0.60.81.6-0.9-1.3-0.9-0.6-1.0-0.9-1.0-1.0-1.0-1.01.00.7-0.90.4-1.0-0.2-0.5
Condit. Reinf. inactive responses1.11.33.6-1.1-1.9-1.1-0.8-1.5-1.1-1.3-1.2-1.2-1.21.41.1-1.20.6-0.9-0.2-0.8
Incentive salience index mean0.30.30.6-0.6-0.7-0.6-0.5-0.6-0.5-0.6-0.7-0.7-0.70.50.1-0.6-0.0-0.8-0.3-0.1
Condit. Reinf. lever presses0.30.40.9-0.7-1.0-0.6-0.5-0.6-0.5-0.6-0.7-0.7-0.70.70.4-0.60.1-0.8-0.3-0.1
Condit. Reinf. active minus inactive responses0.91.12.4-0.50.4-1.1-1.1-0.8-1.1-0.9-0.7-0.7-0.7-1.0-1.5-1.0-1.3-1.4-1.4-1.3
Condit. Reinf. active-inactive response ratio0.80.92.2-0.10.9-0.8-0.8-0.5-0.9-0.5-0.4-0.4-0.4-1.1-1.5-0.7-1.5-1.3-1.3-1.2
Condit. Reinf. active responses0.40.62.60.11.1-0.3-0.5-0.0-0.4-0.20.10.10.1-1.4-1.6-0.2-1.1-0.7-0.9-0.8
Condit. Reinf. inactive responses0.20.30.80.40.90.50.20.60.40.50.70.70.7-0.6-0.70.5-0.20.30.00.2
Condit. Reinf. lever presses0.50.70.9-0.9-0.8-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.9-0.1-0.7-0.8-0.4-0.8-0.7-0.8
Condit. Reinf. lever reinforcers received0.50.73.1-0.00.9-0.5-0.7-0.1-0.6-0.3-0.1-0.1-0.1-1.5-1.8-0.3-1.2-0.9-1.0-1.0
Conditioned reinforcement - actives0.30.61.3-0.80.2-1.1-1.0-0.7-1.0-0.8-0.7-0.6-0.60.0-1.1-0.8-0.7-0.5-0.8-0.9
Conditioned reinforcement - inactives3.45.08.6-2.1-1.0-2.4-2.5-2.4-2.4-2.5-2.4-2.4-2.4-0.0-1.4-2.5-1.9-2.5-2.4-2.9
Conditioned locomotion1.41.84.4-0.90.7-1.3-1.4-0.9-1.5-1.0-0.9-0.9-0.9-0.8-2.1-1.1-2.0-1.4-1.8-1.8
Patch foraging indifference point 0 sec0.61.01.5-0.8-0.9-1.0-1.0-1.2-1.1-1.1-1.1-1.1-1.1-0.5-0.7-1.2-0.8-1.2-1.0-1.1
Patch foraging indifference point AUC0.81.22.3-1.5-0.9-1.4-1.3-1.3-1.1-1.3-1.3-1.3-1.30.6-0.6-1.3-0.3-1.0-0.9-0.4
Delay disc. indifference point, 0s delay0.20.31.3-0.10.5-0.1-0.3-0.0-0.20.20.10.20.2-0.6-1.1-0.2-1.1-0.4-0.8-0.7
Delay disc. indifference point, 16s delay2.12.34.4-1.9-1.3-2.1-1.7-1.8-1.9-1.6-1.6-1.7-1.70.8-0.7-1.7-0.3-1.7-1.1-1.1
Delay disc. indifference point, 2s delay1.01.13.1-1.8-0.4-1.7-1.3-0.9-1.6-0.8-0.6-0.5-0.51.5-0.8-1.0-0.5-0.8-1.0-0.6
Delay disc. indifference point, 24s delay0.50.61.7-0.6-0.5-0.9-0.8-0.8-0.7-0.8-0.8-0.9-0.9-0.4-0.7-0.9-0.6-1.3-0.8-0.3
Delay disc. indifference point, 4s delay1.01.12.1-1.4-0.6-1.4-1.2-1.0-1.3-0.8-0.9-0.9-0.90.6-0.8-1.1-0.8-1.3-1.2-0.8
Delay disc. indifference point, 8s delay1.72.03.5-1.9-1.5-1.8-1.6-1.7-1.6-1.5-1.6-1.6-1.61.1-0.4-1.6-0.4-1.5-1.1-0.8
Indifference point function ln k1.73.04.32.11.42.12.02.11.91.92.02.02.0-0.80.82.00.81.71.61.3
Indifference point function log k1.73.04.32.11.42.12.02.11.91.92.02.02.0-0.80.82.00.81.71.61.3
Patch foraging total patch changes 0 sec0.71.41.9-1.2-1.3-1.3-1.2-1.4-1.3-1.4-1.3-1.3-1.30.0-0.5-1.3-0.7-1.3-1.0-1.1
Patch foraging total patch changes 12 sec0.40.52.1-0.60.1-0.7-0.9-0.6-0.7-0.6-0.4-0.4-0.4-0.8-1.5-0.7-0.9-0.8-0.9-0.6
Patch foraging total patch changes 18 sec2.43.65.2-1.6-0.7-1.8-2.1-1.9-2.0-2.0-2.0-2.0-2.0-0.8-1.9-2.1-2.0-2.2-2.3-2.0
Patch foraging total patch changes 24 sec0.50.81.5-1.2-0.8-1.0-1.1-1.0-0.8-1.0-1.1-1.1-1.10.3-0.4-1.0-0.5-0.9-0.9-0.6
Patch foraging total patch changes 6 sec2.74.06.1-2.0-1.4-2.0-2.2-2.3-2.0-2.3-2.2-2.2-2.20.1-1.3-2.5-1.7-2.2-2.3-1.9
Patch foraging time to switch 0 sec0.00.10.40.10.4-0.0-0.20.2-0.20.20.10.10.1-0.3-0.60.1-0.6-0.2-0.4-0.5
Patch foraging water rate 0 sec0.30.50.9-0.4-0.7-0.6-0.6-0.9-0.6-0.9-0.9-0.9-0.9-0.4-0.2-0.9-0.6-0.8-0.7-0.8
Patch foraging water rate 12 sec0.10.20.9-0.3-0.9-0.00.0-0.4-0.1-0.4-0.4-0.4-0.40.60.7-0.30.6-0.10.30.0
Patch foraging water rate 18 sec0.50.71.8-0.5-1.2-0.5-0.7-1.2-0.6-1.3-1.1-1.1-1.1-0.20.1-1.1-0.2-0.9-0.6-0.7
Patch foraging water rate 24 sec0.30.41.21.10.41.10.80.60.90.50.60.60.6-1.10.00.60.10.30.50.4
Patch foraging water rate 6 sec0.30.52.00.2-1.30.30.4-0.00.4-0.1-0.1-0.1-0.10.21.20.31.40.41.00.8
Seeking ratio, delayed vs. immediate footshock0.40.52.8-0.9-0.9-0.5-0.3-0.7-0.4-0.7-0.5-0.5-0.51.71.1-0.60.5-0.40.0-0.2
Distance traveled before self-admin1.01.32.6-1.6-0.6-1.4-1.4-1.2-1.5-1.2-1.2-1.2-1.20.7-0.9-1.1-0.7-1.1-1.1-1.0
Distance traveled after self-admin2.73.35.0-1.0-0.5-1.7-1.9-2.0-1.8-1.9-1.8-1.8-1.8-1.3-2.0-2.0-2.0-2.0-2.1-2.2
Extensor digitorum longus weight0.51.96.2-2.1-2.3-1.5-1.0-1.0-1.3-1.1-1.6-1.6-1.62.50.9-0.80.5-0.5-0.30.2
Bone: elastic displacement0.10.10.40.50.10.40.40.40.40.40.20.20.2-0.7-0.10.50.10.30.30.2
Bone: elastic work0.70.93.40.71.40.40.10.80.10.50.40.40.4-1.7-1.80.3-1.7-0.3-0.9-0.5
Bone: endosteal estimation0.40.94.20.91.50.3-0.10.40.20.40.50.40.4-2.1-1.7-0.0-1.6-0.6-0.9-0.7
Bone: endosteal perimeter0.71.44.21.52.01.20.81.30.91.11.31.21.2-1.9-1.10.9-1.00.3-0.10.1
Epididymis fat weight2.48.214.63.83.73.43.13.42.93.33.43.43.4-2.1-0.23.1-0.22.31.51.8
Delta time in closed arm before/after self-admin0.10.10.5-0.40.6-0.4-0.2-0.0-0.30.00.10.10.10.7-0.4-0.2-0.4-0.0-0.3-0.1
Delta time in open arm before/after self-admin0.30.30.8-0.3-0.6-0.6-0.5-0.9-0.6-0.7-0.6-0.6-0.60.10.1-0.6-0.0-0.6-0.3-0.7
Diff in mean of infusions in LGA sessions0.10.20.90.40.70.0-0.10.0-0.10.0-0.1-0.1-0.1-1.0-0.4-0.1-0.8-0.2-0.5-0.4
Delay discount exponential model param1.61.83.71.91.11.91.51.51.71.31.31.31.3-1.00.71.50.51.51.20.7
Extinction: sum of active levers before priming0.30.41.50.11.2-0.3-0.30.2-0.40.20.40.40.4-0.4-0.9-0.1-1.1-0.4-0.9-0.9
Active lever presses in extinction session 60.10.10.50.20.70.00.00.2-0.00.20.20.20.2-0.2-0.20.1-0.5-0.1-0.3-0.6
Bone: final force0.50.94.10.11.2-0.2-0.40.3-0.50.10.10.10.1-1.3-2.0-0.3-2.0-0.9-1.4-0.6
Bone: final moment0.61.04.70.11.2-0.2-0.50.2-0.50.00.0-0.0-0.0-1.4-2.1-0.4-2.2-1.0-1.5-0.8
Food consumed during 24 hour testing period0.40.62.40.41.30.2-0.20.2-0.10.10.20.20.2-1.3-1.3-0.1-1.5-0.4-1.0-0.6
Glucose0.10.21.30.40.3-0.1-0.2-0.1-0.10.0-0.0-0.0-0.0-1.1-0.6-0.1-0.6-0.5-0.4-0.8
Heart weight0.91.34.91.62.01.00.50.70.70.60.80.80.8-2.2-1.30.2-1.9-0.1-0.8-1.0
Delay discount hyperbolic model param1.51.63.61.91.11.91.51.31.71.21.21.11.1-1.20.61.40.41.41.10.7
Intermittent access intake day 1-15 change0.10.20.6-0.2-0.6-0.4-0.1-0.5-0.3-0.5-0.5-0.4-0.40.80.6-0.40.50.00.2-0.3
Intermittent access intake escalation0.10.20.9-0.2-0.9-0.3-0.1-0.5-0.2-0.5-0.4-0.3-0.31.00.8-0.40.70.20.4-0.1
Intermittent access intake escalation 20.30.30.8-0.4-0.9-0.4-0.2-0.7-0.3-0.7-0.6-0.5-0.50.90.7-0.60.40.10.2-0.4
Intermitt. access day 1 inactive lever presses0.31.25.10.10.4-0.3-0.9-0.6-0.5-0.6-0.5-0.6-0.6-2.3-1.9-0.7-1.7-1.3-1.3-1.6
Intermitt. access day 15 inactive lever presses0.91.83.7-1.0-0.8-1.3-1.5-1.5-1.2-1.4-1.4-1.4-1.4-0.5-0.9-1.5-1.2-1.5-1.4-1.9
Intermitt. access escalation Index0.30.42.1-0.6-0.90.0-0.0-0.30.1-0.3-0.3-0.4-0.41.51.0-0.20.80.30.30.6
Intermittent access day 1 total infusions1.11.73.4-1.10.6-1.4-1.6-0.9-1.4-1.0-0.9-0.9-0.9-0.7-1.8-1.1-1.9-1.6-1.8-1.7
Intermittent access day 15 total infusions0.91.32.4-1.3-0.6-1.6-1.4-1.2-1.4-1.3-1.2-1.1-1.10.6-0.6-1.3-0.5-1.2-1.0-1.2
Intermittent access terminal intake (last 3 days)0.91.22.2-1.2-0.3-1.5-1.3-1.2-1.4-1.3-1.2-1.0-1.00.5-0.6-1.2-0.6-1.0-0.9-1.3
Intermittent access total infusions2.32.85.4-1.60.3-2.0-2.0-1.5-2.0-1.6-1.4-1.4-1.4-0.2-1.7-1.7-1.8-1.9-2.0-2.3
Intermittent access day 1 locomotion2.12.65.6-1.5-0.1-1.6-1.8-1.5-1.7-1.6-1.5-1.5-1.5-0.4-1.6-1.6-1.8-1.9-2.0-2.4
Intermittent access day 15 total locomotion0.61.13.4-0.50.6-0.8-1.0-0.8-0.9-0.8-0.7-0.7-0.7-0.6-1.1-1.0-1.6-1.3-1.5-1.9
Intermittent access total locomotion1.72.05.4-0.70.6-1.0-1.4-1.2-1.1-1.2-1.1-1.1-1.1-1.1-1.7-1.4-2.1-1.6-2.0-2.3
Intermittent access standard deviation1.12.26.9-0.50.6-1.3-1.5-1.1-1.5-1.1-1.0-0.9-0.9-1.7-2.6-1.3-2.1-1.4-1.8-2.2
Left kidney weight4.320.146.86.16.84.74.05.24.05.25.15.15.1-5.5-2.54.2-2.22.71.01.7
Right kidney weight4.822.053.86.67.34.94.15.34.15.35.15.15.1-6.4-2.94.2-2.72.60.81.3
Cocaine induced anxiety0.60.92.81.11.71.10.91.10.91.11.11.11.1-0.7-0.10.8-0.60.70.0-0.1
Post-drug Anxiety0.70.81.41.10.61.21.10.91.20.90.90.90.9-0.20.70.80.50.90.80.7
Baseline Anxiety0.50.62.2-0.9-1.5-0.8-0.4-0.8-0.5-0.8-0.8-0.8-0.81.20.4-0.41.0-0.30.40.5
Tail length0.10.21.10.4-1.10.20.3-0.20.2-0.3-0.4-0.4-0.4-0.50.8-0.10.5-0.10.4-0.0
Length with tail0.52.36.42.51.41.81.91.71.61.71.51.41.4-2.10.11.60.01.01.00.9
Length without tail1.13.59.92.73.11.91.61.91.61.91.81.81.8-3.2-1.51.5-1.50.80.00.2
Times rat made contact with spout0.10.10.3-0.2-0.2-0.4-0.3-0.5-0.3-0.5-0.4-0.4-0.40.2-0.1-0.5-0.4-0.2-0.5-0.5
Lifetime Intake2.32.85.6-1.40.9-1.8-2.0-1.3-1.9-1.3-1.2-1.1-1.1-0.6-2.2-1.6-2.3-1.9-2.3-2.4
Liver weight, left2.23.75.21.91.22.12.12.02.22.02.12.12.10.01.22.21.52.22.02.3
Liver weight, right5.79.915.33.62.13.93.73.33.83.13.33.33.3-0.52.23.52.33.53.33.0
Locomotor activity0.60.92.11.41.21.21.11.01.10.91.01.01.0-1.0-0.20.9-0.40.70.40.5
Locomotor testing distance0.10.10.6-0.2-0.70.00.1-0.20.1-0.3-0.3-0.3-0.30.60.5-0.10.30.10.10.4
Locomotor testing rearing0.50.92.21.21.51.10.91.10.91.11.11.11.1-0.7-0.41.0-0.30.90.40.7
Locomotion in novel chamber1.01.24.4-0.6-2.0-0.20.2-0.40.1-0.4-0.4-0.4-0.42.02.10.12.00.71.31.1
Locomotion in novel chamber post-restriction0.30.43.0-0.9-0.9-0.5-0.1-0.3-0.4-0.3-0.2-0.2-0.21.71.0-0.11.00.30.40.3
Fecal boli incidents, locomotor time 11.62.43.7-1.3-0.5-1.5-1.8-1.7-1.5-1.7-1.4-1.5-1.5-0.9-1.6-1.8-1.7-1.8-1.9-1.6
Change in fecal boli incidents, locomotor task2.82.74.11.81.21.81.81.82.01.91.71.71.7-0.30.81.71.21.71.72.0
Time >=10cm from walls, locomotor time 10.60.63.50.61.20.2-0.10.2-0.00.10.10.20.2-1.9-1.40.0-1.2-0.6-0.7-0.8
Bouts of movement, locomotor time 11.01.11.91.31.21.21.01.31.21.41.31.21.2-1.1-0.11.3-0.00.90.50.7
Total resting periods, locomotor time 10.40.41.40.70.90.70.40.80.60.80.60.50.5-1.2-0.60.7-0.50.2-0.00.2
Rest time, locomotor task time 10.30.41.50.40.90.4-0.10.40.30.40.10.10.1-1.2-1.20.1-1.2-0.1-0.6-0.2
Distance moved, locomotor task time 10.50.81.30.70.20.81.00.90.70.80.90.90.90.61.00.91.00.91.10.9
Vertical activity count, locomotor time 10.00.10.40.5-0.30.20.2-0.20.1-0.2-0.1-0.0-0.0-0.40.6-0.10.00.00.1-0.2
Time >=10cm from walls, locomotor time 20.20.21.60.30.10.0-0.2-0.2-0.0-0.3-0.3-0.3-0.3-1.3-0.6-0.3-0.5-0.6-0.4-0.8
Bouts of movement, locomotor time 20.40.61.00.30.60.80.70.80.80.90.90.90.90.90.60.90.61.00.70.7
Total resting periods, locomotor time 20.10.20.8-0.10.50.40.30.40.40.60.60.60.60.90.30.40.20.60.20.4
Rest time, locomotor task time 20.20.20.6-0.4-0.3-0.4-0.6-0.3-0.4-0.4-0.6-0.6-0.6-0.2-0.8-0.5-0.5-0.5-0.6-0.0
Distance moved, locomotor task time 20.60.71.20.90.60.91.01.00.70.90.91.01.0-0.10.41.10.71.01.00.6
Vertical activity count, locomotor time 20.10.20.90.80.50.50.30.20.40.20.20.30.3-0.90.00.1-0.30.3-0.0-0.2
Light reinforcement 10.10.30.5-0.7-0.2-0.6-0.6-0.5-0.7-0.5-0.5-0.5-0.50.2-0.2-0.6-0.4-0.6-0.6-0.7
Light reinforcement 21.32.02.81.11.31.51.51.71.41.61.71.71.70.51.01.71.01.61.41.5
Bone: marrow area0.41.04.50.91.50.3-0.10.40.20.40.40.40.4-2.1-1.7-0.1-1.7-0.6-1.0-0.8
Bone: maximum diameter1.01.86.31.52.50.90.51.20.61.11.21.11.1-2.2-2.00.5-2.1-0.4-1.0-0.3
Bone: maximum force0.91.77.50.11.5-0.4-0.70.1-0.7-0.1-0.2-0.2-0.2-1.8-2.6-0.6-2.7-1.3-2.0-1.0
Bone: maximum moment1.01.88.10.21.7-0.3-0.70.1-0.7-0.2-0.2-0.2-0.2-1.8-2.7-0.6-2.9-1.3-2.0-1.1
Mean time between licks in bursts0.30.82.7-1.3-1.3-1.0-0.6-0.8-0.9-0.8-0.9-0.9-0.91.60.7-0.60.5-0.2-0.0-0.3
Mean num. licks in bursts0.60.92.01.31.41.11.01.01.01.01.11.11.1-0.7-0.30.9-0.30.80.40.4
Cd content in liver0.40.40.90.91.00.60.90.60.60.50.70.70.70.00.60.50.30.60.60.8
Co content in liver1.41.62.1-1.4-1.1-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.40.1-0.6-1.4-1.0-1.3-1.3-1.2
Cu content in liver4.25.010.3-2.8-3.2-2.6-2.0-2.3-2.4-2.4-2.5-2.5-2.52.71.0-2.10.3-2.0-1.1-1.2
Fe content in liver0.70.95.11.21.10.40.10.10.00.00.10.10.1-2.3-1.2-0.2-1.7-0.9-0.9-1.0
K content in liver0.20.21.2-0.3-1.1-0.5-0.4-0.4-0.4-0.5-0.5-0.5-0.50.20.1-0.30.4-0.20.1-0.2
Mg content in liver0.40.50.8-0.3-0.6-0.8-0.7-0.9-0.8-0.8-0.7-0.7-0.70.0-0.2-0.8-0.3-0.7-0.5-0.9
Mn content in liver0.60.61.20.60.20.70.80.60.80.70.70.70.70.60.70.71.11.11.01.1
Na content in liver0.70.71.4-0.6-1.2-0.9-0.8-1.2-0.8-0.9-1.0-1.0-1.00.20.3-1.0-0.1-0.8-0.5-0.8
Rb content in liver0.70.81.7-0.8-0.3-1.0-1.0-0.8-1.0-0.8-0.8-0.8-0.8-0.2-0.9-0.9-1.2-1.1-1.3-0.8
Se content in liver0.80.93.60.2-1.10.30.80.30.40.40.20.20.21.91.80.51.60.81.31.2
Sr content in liver2.01.87.6-1.7-2.4-1.1-0.7-1.0-0.9-1.1-1.1-1.1-1.12.81.5-0.81.3-0.10.30.5
Zn content in liver0.10.10.3-0.0-0.5-0.10.10.2-0.00.1-0.1-0.1-0.10.50.40.20.4-0.20.20.3
Bone: minimum diameter0.30.52.00.41.10.2-0.20.30.10.20.20.20.2-1.2-1.4-0.1-1.4-0.6-0.9-0.5
Time in familiar zone, hab. session 10.10.10.3-0.20.2-0.4-0.4-0.1-0.2-0.1-0.2-0.2-0.2-0.4-0.4-0.3-0.6-0.5-0.6-0.1
Time in novel zone, hab. session 10.20.20.60.80.50.70.60.30.50.30.30.40.4-0.30.20.30.10.50.4-0.2
Total zone transitions, hab. session 11.01.45.5-1.0-2.3-0.9-0.2-0.7-0.4-0.8-0.9-0.8-0.82.12.0-0.31.9-0.10.90.8
Total locomotion distance, hab. session 10.60.83.8-0.0-1.50.10.50.10.50.00.00.00.01.01.70.51.90.41.31.2
Locomotion velocity, hab. session 10.50.63.1-0.5-1.8-0.40.0-0.3-0.0-0.4-0.4-0.4-0.41.11.40.01.5-0.20.80.8
Time in familiar zone, hab. session 21.01.12.50.3-0.40.71.00.80.90.90.90.80.80.91.51.01.61.21.41.4
Time in novel zone, hab. session 21.11.12.5-0.30.3-0.8-1.0-0.9-1.0-0.9-0.9-0.8-0.8-1.1-1.6-1.1-1.5-1.1-1.4-1.4
Total zone transitions, hab. session 21.72.23.6-1.6-1.2-1.9-1.7-1.5-1.7-1.6-1.8-1.7-1.70.3-0.5-1.7-0.8-1.8-1.4-1.2
Total locomotion distance, hab. session 21.72.23.1-1.6-1.3-1.8-1.7-1.5-1.6-1.6-1.7-1.7-1.7-0.1-1.0-1.6-0.9-1.7-1.4-1.3
Locomotion velocity, hab. session 22.23.04.3-1.9-1.6-2.1-2.0-1.8-1.9-1.9-2.0-2.0-2.0-0.0-1.0-1.9-0.9-1.9-1.6-1.5
Novel to familiar place preference ratio0.80.92.51.61.01.11.30.81.00.91.01.01.0-0.50.80.80.21.10.80.4
Novelty place preference1.61.73.92.01.31.51.71.21.41.31.41.41.4-0.51.01.20.51.51.20.9
Time in novel zone, NPP test1.92.04.62.11.51.61.91.31.51.41.51.51.5-0.51.11.30.51.51.30.9
Total zone transitions, NPP test1.21.75.6-1.5-2.4-1.6-1.1-1.3-1.2-1.4-1.5-1.5-1.51.30.8-1.01.1-0.80.0-0.0
Total locomotion distance, NPP test0.70.92.4-1.2-1.5-1.3-1.0-1.0-1.0-1.1-1.2-1.1-1.10.2-0.2-0.90.2-0.9-0.4-0.3
Locomotion velocity, NPP test0.81.13.3-1.4-1.8-1.3-1.1-1.1-1.1-1.2-1.3-1.3-1.30.60.0-0.90.5-0.8-0.3-0.2
Intraocular pressure0.91.32.41.21.51.11.01.51.01.41.31.31.3-1.1-0.31.40.10.90.70.9
Delta distance traveled before/after self-admin0.50.64.41.30.70.40.30.00.40.10.20.20.2-2.1-1.0-0.1-1.0-0.2-0.4-0.3
Delta ambulatory time before/after self-admin0.50.74.81.10.80.20.0-0.10.1-0.00.00.00.0-2.2-1.4-0.3-1.2-0.5-0.7-0.6
Parametrial fat weight0.61.53.51.1-0.41.51.40.91.60.80.80.80.80.11.41.11.41.61.51.9
Pavlov. Cond. lever latency0.00.10.20.40.50.20.20.10.10.20.30.20.2-0.20.10.2-0.10.40.10.0
Pavlov. Cond. magazine entry latency0.50.71.6-1.3-0.9-1.1-1.1-0.8-0.9-0.8-0.9-0.9-0.90.6-0.6-0.9-0.3-0.7-0.7-0.5
Pavlov. Cond. change in total contacts2.02.13.1-1.8-1.2-1.7-1.7-1.6-1.6-1.5-1.5-1.5-1.50.7-1.0-1.7-0.9-1.5-1.5-1.3
Pavlov. Cond. index score0.30.40.7-0.8-0.5-0.7-0.8-0.5-0.6-0.5-0.6-0.6-0.6-0.0-0.8-0.6-0.5-0.7-0.7-0.5
Pavlov. Cond. latency score0.20.30.4-0.7-0.5-0.6-0.6-0.4-0.4-0.5-0.6-0.5-0.50.0-0.6-0.5-0.3-0.6-0.5-0.4
Pavlov. Cond. lever contacts0.40.51.2-1.0-1.1-0.8-0.9-0.8-0.6-0.8-0.8-0.8-0.80.4-0.3-0.7-0.0-0.8-0.5-0.4
Pavlov. Cond. magazine entry number0.50.71.71.30.91.11.00.80.80.80.90.90.9-0.70.50.80.20.60.70.4
Pavlov. Cond. intertrial magazine entries1.41.62.6-0.9-1.1-1.4-1.2-1.6-1.4-1.6-1.6-1.5-1.50.1-0.0-1.6-0.7-1.5-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.8-0.5-0.7-0.7-0.4-0.5-0.4-0.5-0.5-0.50.2-0.6-0.5-0.3-0.6-0.5-0.3
Pavlov. Cond. response bias0.40.61.4-1.2-0.8-0.9-1.0-0.7-0.8-0.6-0.7-0.7-0.70.6-0.6-0.7-0.3-0.8-0.7-0.4
Pavlov. Cond. lever latency0.70.91.70.81.00.81.01.01.01.11.01.01.00.40.71.00.61.10.91.3
Pavlov. Cond. magazine entry latency3.54.25.8-2.1-1.8-2.3-2.3-2.3-2.4-2.3-2.2-2.2-2.20.2-1.2-2.3-1.3-2.2-2.0-2.1
Pavlov. Cond. change in total contacts2.23.57.7-0.6-0.0-1.2-1.8-1.5-1.6-1.6-1.4-1.4-1.4-2.4-2.8-1.8-2.6-2.3-2.4-2.6
Pavlov. Cond. index score1.82.43.2-1.4-1.4-1.6-1.7-1.7-1.7-1.8-1.7-1.7-1.7-0.5-1.3-1.7-1.1-1.7-1.6-1.8
Pavlov. Cond. latency score2.22.93.9-1.5-1.6-1.8-1.9-1.8-1.9-2.0-1.8-1.8-1.8-0.4-1.3-1.8-1.1-1.9-1.7-1.9
Pavlov. Cond. lever contacts0.71.01.7-0.9-1.1-0.9-1.1-1.1-1.1-1.2-1.1-1.1-1.1-0.4-0.7-1.1-0.6-1.2-0.9-1.3
Pavlov. Cond. magazine entry number1.31.62.41.11.21.41.41.41.41.51.31.31.30.20.91.40.91.41.31.5
Pavlov. Cond. intertrial magazine entries0.20.41.90.61.40.60.30.50.50.60.60.60.6-0.8-0.70.2-0.70.3-0.20.2
Pavlov. Cond. lever-magazine prob. diff.1.72.33.2-1.4-1.5-1.6-1.7-1.6-1.7-1.8-1.6-1.6-1.6-0.4-1.2-1.6-1.1-1.7-1.5-1.7
Pavlov. Cond. response bias1.42.02.9-1.2-1.1-1.3-1.6-1.5-1.5-1.6-1.5-1.5-1.5-0.6-1.3-1.5-1.2-1.6-1.5-1.7
Time in closed arm before self-admin2.83.65.7-2.1-2.1-1.8-1.9-2.3-1.9-2.4-2.3-2.3-2.31.0-0.3-2.2-0.7-1.8-1.5-1.8
Time in closed arm after self-admin0.20.20.7-0.40.3-0.2-0.4-0.5-0.3-0.5-0.4-0.4-0.40.3-0.6-0.6-0.8-0.4-0.7-0.4
Time in open arm before self-admin0.80.91.90.6-0.00.91.01.21.01.00.80.80.8-0.10.71.11.21.01.31.4
Time in open arm after self-admin0.40.41.90.2-0.80.20.50.10.40.20.20.20.20.61.40.41.30.41.00.3
Bone: periosteal estimation0.51.13.60.81.80.4-0.00.60.10.50.60.50.5-1.8-1.90.0-1.9-0.7-1.1-0.6
Bone: periosteal perimeter1.32.26.91.82.61.41.01.71.01.31.41.41.4-2.4-1.71.1-1.50.2-0.30.1
Bone: post-yield work1.11.73.9-0.70.5-1.2-1.3-0.9-1.3-1.2-1.1-1.1-1.1-0.6-1.3-1.4-2.0-1.7-1.9-1.5
Progressive ratio test 1 active lever presses1.61.93.4-1.30.3-1.7-1.7-1.1-1.7-1.1-1.0-1.1-1.1-0.3-1.8-1.3-1.7-1.6-1.8-1.6
Progressive ratio test 1 breakpoint1.41.72.8-1.30.2-1.6-1.6-1.0-1.6-1.1-1.0-1.1-1.1-0.3-1.6-1.2-1.5-1.5-1.7-1.5
Progressive ratio test 1 inactive lever presses3.14.57.7-2.0-0.1-2.2-2.5-1.9-2.3-2.0-1.9-2.0-2.0-0.8-2.4-2.2-2.5-2.3-2.7-2.8
Progressive ratio test 2 active lever presses1.01.22.4-1.00.4-1.2-1.4-0.9-1.1-0.9-0.8-0.8-0.8-0.4-1.5-1.1-1.4-1.3-1.5-1.3
Progressive ratio test 2 breakpoint1.01.12.1-1.00.3-1.2-1.4-0.9-1.1-0.9-0.8-0.7-0.7-0.3-1.5-1.1-1.3-1.2-1.4-1.2
Progressive ratio test 2 inactive lever presses1.21.92.9-1.6-0.9-1.6-1.7-1.6-1.5-1.6-1.5-1.5-1.50.5-0.4-1.5-0.7-1.5-1.3-1.7
Incentive Sensitization - Responses0.00.00.1-0.2-0.3-0.1-0.3-0.20.0-0.3-0.2-0.2-0.2-0.2-0.1-0.20.2-0.1-0.00.2
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.1-0.1-0.3-0.20.1-0.2-0.1-0.1-0.1-0.3-0.2-0.10.0-0.0-0.10.2
Sum of active levers in priming session hrs 5-60.00.00.30.1-0.0-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.1-0.3-0.1-0.5
Progressive ratio0.40.61.0-0.6-0.1-0.9-0.8-0.8-0.9-0.9-0.9-0.9-0.9-0.4-0.6-0.8-0.9-1.0-0.9-1.0
Food seeking constrained by brief footshock0.10.11.10.11.00.10.10.4-0.00.40.40.40.40.2-0.40.1-0.6-0.2-0.4-0.2
Seeking ratio, punishment vs. effort0.10.20.50.40.70.50.30.50.40.60.60.60.60.1-0.30.4-0.10.30.00.3
Retroperitoneal fat weight3.213.623.74.64.94.43.94.33.84.24.44.44.4-2.6-0.33.9-0.23.22.02.7
Reaction time number correct0.91.64.70.5-0.61.11.20.91.30.80.90.90.91.21.71.22.21.51.81.8
Reaction time mean minus median0.00.10.20.1-0.2-0.3-0.2-0.3-0.3-0.30.10.00.0-0.5-0.3-0.2-0.1-0.1-0.1-0.4
Reaction time mean minus median AUC0.20.40.91.00.50.60.60.60.60.60.80.80.8-0.8-0.10.60.10.70.50.2
Reaction time num false alarms0.00.00.20.2-0.20.10.2-0.00.2-0.1-0.0-0.0-0.00.00.50.20.30.10.30.1
Reaction time num false alarms AUC0.10.10.50.2-0.20.20.40.10.2-0.00.10.10.10.20.70.30.60.30.60.3
Reaction time trials correct on left0.91.64.70.5-0.61.11.20.91.30.80.90.90.91.21.71.22.21.51.81.8
Reaction time trials on left0.91.64.80.5-0.61.01.10.81.20.80.90.90.91.21.81.12.21.51.81.8
Reaction time mean0.00.10.30.2-0.1-0.2-0.2-0.2-0.3-0.2-0.1-0.1-0.1-0.6-0.3-0.2-0.2-0.4-0.1-0.3
Reaction time mean AUC0.00.00.20.2-0.0-0.1-0.1-0.1-0.1-0.10.10.10.1-0.5-0.2-0.0-0.0-0.30.0-0.1
Median of all reaction times0.00.00.20.1-0.1-0.2-0.2-0.2-0.3-0.2-0.1-0.1-0.1-0.4-0.3-0.2-0.1-0.4-0.1-0.2
Reaction time omissions0.10.20.4-0.6-0.5-0.6-0.4-0.3-0.4-0.2-0.3-0.3-0.30.60.2-0.20.5-0.20.10.2
Reaction time false alarm rate0.00.10.2-0.00.0-0.3-0.1-0.3-0.3-0.3-0.3-0.3-0.3-0.10.0-0.2-0.3-0.3-0.2-0.4
Reaction time premature initiation rate1.41.94.3-0.50.1-0.9-1.4-1.1-1.1-1.1-1.0-1.0-1.0-1.8-2.1-1.3-2.1-1.9-1.9-1.5
Reaction time premature initiations0.20.41.7-0.00.1-0.2-0.6-0.4-0.3-0.4-0.3-0.3-0.3-1.3-1.2-0.5-0.9-0.9-0.8-0.4
Std. dev. reaction times0.10.21.10.80.40.30.30.20.20.20.40.40.4-1.1-0.30.2-0.10.10.2-0.1
Reaction time trials completed0.91.64.80.5-0.61.01.10.81.20.80.90.90.91.21.81.12.21.51.81.8
Reaction time trials AUC0.81.63.90.6-0.31.21.20.91.30.91.01.01.01.01.61.22.01.51.71.8
Run reversals in cocaine runway, females0.30.30.60.7-0.50.60.50.10.70.20.30.30.3-0.50.60.30.80.40.70.4
Run reversals in cocaine runway, males0.60.61.30.61.10.30.71.10.41.00.80.80.80.0-0.21.00.20.70.61.0
Latency to leave start box in cocaine runway0.91.11.61.00.81.11.11.30.91.31.21.21.2-0.00.31.20.61.21.01.0
Latency to leave start box in cocaine runway, F0.00.10.2-0.00.1-0.10.10.3-0.10.30.30.30.30.40.10.20.20.20.20.2
Latency to leave start box in cocaine runway, M2.52.33.61.81.11.91.61.81.71.71.71.71.7-0.80.51.70.71.71.41.4
Std. dev. time between licks in bursts1.11.62.2-1.3-1.4-1.4-1.3-1.4-1.3-1.3-1.5-1.5-1.50.1-0.4-1.3-0.7-1.5-1.1-1.1
Total sessions with >9 infusions1.31.66.2-0.02.2-0.5-0.80.1-0.80.00.10.10.1-1.6-2.5-0.3-2.4-0.9-1.7-1.5
Short access day 1 total inactive lever presses5.26.912.9-1.50.1-2.4-2.7-2.2-2.7-2.2-2.2-2.2-2.2-2.3-3.1-2.6-3.6-3.4-3.5-3.6
Short access day 10 total inactive lever presses0.10.42.80.80.60.60.10.10.50.10.20.20.2-1.7-0.6-0.1-0.8-0.2-0.3-0.5
Short access day 1 total infusions1.31.84.1-0.50.8-1.1-1.3-0.9-1.3-0.9-0.9-0.8-0.8-1.7-1.9-1.1-2.0-1.5-1.8-1.9
Short access day 10 total infusions0.91.24.9-0.31.6-0.6-0.9-0.2-0.8-0.2-0.1-0.1-0.1-1.0-2.2-0.6-2.0-0.9-1.6-1.4
Short access total infusions1.92.47.4-0.71.8-1.2-1.5-0.7-1.4-0.7-0.6-0.5-0.5-1.3-2.6-1.1-2.7-1.6-2.3-2.1
Short access day 1 locomotion0.91.22.6-0.60.1-0.9-1.1-0.8-1.1-0.9-0.9-0.8-0.8-1.2-1.6-0.9-1.5-1.2-1.3-1.5
Short access day 10 total locomotion1.42.73.8-1.3-1.0-1.4-1.9-1.7-1.5-1.7-1.6-1.7-1.7-1.2-1.9-1.7-1.6-1.5-1.8-1.9
Short access total locomotion1.31.65.0-0.70.5-1.0-1.3-0.8-1.2-0.9-0.8-0.9-0.9-1.4-2.2-1.0-1.9-1.2-1.7-1.6
One hour access (0.3 mA shock)2.22.65.3-2.3-0.8-2.1-1.9-1.7-1.9-1.7-1.5-1.5-1.51.9-0.3-1.6-0.6-1.4-1.3-1.9
Compulsive drug intake0.20.20.8-0.5-0.8-0.2-0.1-0.40.0-0.3-0.3-0.4-0.40.80.9-0.30.5-0.10.10.6
One hour access (shock baseline)0.61.02.7-1.3-0.1-1.2-1.2-0.9-1.3-1.0-0.9-0.7-0.70.9-0.6-0.9-0.7-0.8-0.9-1.7
Social response proportion0.40.41.9-0.50.1-0.6-0.5-0.5-0.8-0.5-0.5-0.5-0.5-0.1-0.7-0.6-0.8-0.6-0.7-1.4
Social responses0.60.81.7-1.1-0.5-1.2-1.0-0.9-1.3-1.0-1.0-1.0-1.0-0.1-0.9-0.9-0.5-0.7-0.8-0.9
Social time2.53.45.7-2.3-1.7-2.4-2.1-2.0-2.3-2.0-2.1-2.1-2.10.6-0.9-1.8-0.5-1.7-1.3-1.7
Soleus weight0.30.71.1-0.8-0.8-0.9-1.1-0.9-0.6-0.9-1.0-1.0-1.0-0.7-1.0-0.8-0.6-0.8-0.9-0.3
Bone: stiffness0.81.25.50.11.2-0.3-0.7-0.1-0.7-0.4-0.3-0.3-0.3-1.4-2.0-0.7-2.3-1.2-1.7-1.1
Tibialis anterior weight1.54.911.0-3.3-2.9-2.7-2.3-2.1-2.5-2.3-2.6-2.6-2.62.60.2-2.1-0.1-1.6-1.3-0.8
Time to tail flick, vehicle, before self-admin0.30.30.8-0.10.1-0.3-0.4-0.5-0.4-0.5-0.4-0.4-0.4-0.5-0.7-0.5-0.7-0.6-0.6-0.9
Time to tail flick, vehicle, after self-admin0.30.41.1-0.3-1.1-0.5-0.4-0.8-0.4-0.8-0.9-0.9-0.9-0.70.2-0.5-0.0-0.7-0.2-0.3
Time to tail flick, test, before self-admin0.70.71.80.20.60.70.71.00.81.00.80.80.80.80.11.00.71.00.81.4
Time to tail flick, test, after self-admin0.20.21.4-0.5-0.6-0.00.0-0.30.0-0.3-0.3-0.3-0.31.21.0-0.20.70.10.30.2
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.5-0.3-0.7-0.6-0.6-0.7-0.5-0.7-0.7-0.7-0.5-0.5-0.5-0.6-0.8-0.7-0.6
Delta time to tail flick, test, before/after SA1.21.23.3-1.0-1.8-0.9-0.6-1.3-0.8-1.4-1.3-1.3-1.31.01.5-1.00.6-0.7-0.1-0.9
Tibia length0.30.92.91.21.70.60.51.00.51.00.80.80.8-1.7-1.20.6-1.1-0.1-0.4-0.0
Ambulatory time before self-admin0.71.02.1-1.5-1.0-1.2-1.1-1.1-1.2-1.1-1.1-1.1-1.11.0-0.2-0.9-0.1-0.7-0.7-0.5
Ambulatory time after self-admin2.12.54.0-1.1-1.3-1.8-1.6-2.0-1.7-1.9-1.8-1.8-1.8-0.6-1.1-1.8-1.1-1.8-1.5-1.6
Bone: tissue strength0.50.50.90.90.90.80.70.80.70.80.80.80.8-0.7-0.20.80.10.50.40.5
Total heroin consumption0.20.20.6-0.40.6-0.5-0.5-0.0-0.6-0.2-0.1-0.1-0.1-0.0-0.6-0.3-0.8-0.6-0.7-0.6
Bone: trabecular number0.30.51.10.50.00.70.80.80.70.70.50.60.60.30.80.80.70.70.81.0
Bone: trabecular spacing0.71.03.80.21.2-0.2-0.6-0.3-0.3-0.2-0.2-0.2-0.2-1.7-2.0-0.6-1.9-0.8-1.4-1.1
Bone: trabecular thickness0.30.41.6-0.0-0.60.40.50.30.40.20.20.20.21.31.20.40.90.60.70.6
Bone: trabecular tissue density1.11.73.7-1.2-1.9-1.3-1.0-1.7-1.3-1.6-1.4-1.4-1.41.41.0-1.50.1-1.1-0.6-1.1
Water consumed over 24 hours0.40.50.8-0.3-0.4-0.6-0.6-0.8-0.7-0.9-0.7-0.7-0.7-0.5-0.7-0.8-0.9-0.6-0.9-0.7
Number of responses in last shaping day4.44.87.9-2.2-0.6-2.4-2.6-2.0-2.7-2.1-2.1-2.1-2.1-0.1-2.2-2.3-2.2-2.3-2.6-2.8