Midn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye alternative TSS XM_008765097.4 0.26 0.16 2.1e-03 0.1 0.15 0.08 0.15 1.2e-02 2.3e-03 2.5e-02 2.9e-03
2 NAcc isoform ratio XM_006240912.5 0.02 0.02 2.8e-04 0.02 0.03 0.02 0.02 1.6e-04 9.4e-05 2.9e-04 1.8e-04
3 IC mRNA stability Midn 0.06 0.05 9.4e-03 0.01 0.01 -0.01 0 1.4e-01 1.2e-01 8.5e-01 2.1e-01
4 OFC alternative TSS XM_006240912.5 0.14 0.1 1.9e-03 0.12 0.09 0.1 0.1 1.2e-03 3.1e-03 2.0e-03 2.6e-03
5 OFC alternative TSS XM_017594815.3 0.12 0.09 4.3e-03 0.11 0.08 0.06 0.09 1.4e-03 6.0e-03 1.7e-02 4.2e-03
6 OFC alternative TSS XM_006240912.5 0.14 0.1 1.8e-03 0.12 0.1 0.1 0.1 1.1e-03 2.9e-03 1.9e-03 2.9e-03
7 OFC alternative TSS XM_017594815.3 0.12 0.09 4.5e-03 0.11 0.08 0.06 0.09 1.5e-03 6.4e-03 1.8e-02 4.2e-03
8 Brain alternative TSS XM_006240912.5 0.07 0.05 1.2e-06 0.06 0.06 0.03 0.06 4.0e-06 5.2e-06 6.4e-04 4.4e-06
9 Brain alternative TSS XM_006240912.5 0.08 0.05 1.0e-06 0.06 0.06 0.04 0.06 2.5e-06 4.7e-06 2.2e-04 3.2e-06
10 Brain isoform ratio XM_006240912.5 0.09 0.06 8.1e-07 0.06 0.06 0.04 0.06 2.2e-06 5.5e-06 1.1e-04 4.7e-06
11 PL alternative TSS XM_017594815.3 0.02 0.02 7.2e-03 0.02 0.01 0.01 0.01 3.1e-03 1.1e-02 1.3e-02 1.4e-02
12 PL alternative TSS XM_017594815.3 0.02 0.02 4.6e-03 0.02 0.02 0.01 0.01 1.8e-03 5.5e-03 8.1e-03 8.3e-03
13 Adipose gene expression Midn 0.06 0.04 1.8e-06 0.05 0.05 0.05 0.05 1.6e-06 3.4e-06 4.3e-06 1.8e-06
14 LHb isoform ratio XM_006240912.5 0.12 0.09 4.9e-03 0.04 0.02 0 0.01 4.3e-02 1.3e-01 3.2e-01 1.4e-01
15 Eye gene expression Midn 0.29 0.18 5.0e-03 0.1 0.07 0.04 0.08 1.4e-02 2.8e-02 9.3e-02 2.6e-02
16 NAcc alternative TSS XM_006240912.5 0.02 0.01 1.0e-03 0.02 0.02 0.02 0.02 5.3e-04 2.4e-04 2.0e-04 4.0e-04
17 Liver mRNA stability Midn 0.02 0.02 8.1e-03 0.02 0.01 0.02 0.01 4.6e-03 2.2e-02 2.0e-03 1.2e-02
18 NAcc alternative TSS XM_006240912.5 0.02 0.01 1.1e-03 0.02 0.02 0.02 0.02 4.1e-04 2.5e-04 1.1e-04 4.5e-04
19 Liver isoform ratio XM_008765097.4 0.03 0.03 2.8e-03 0.01 0.02 0.01 0.01 5.6e-02 4.9e-03 8.3e-03 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.30.63.3-0.00.3-0.40.9-0.90.9-0.9-0.8-0.8-0.80.70.70.7-0.70.7-0.3-0.5-0.61.8
Area under the delay curve1.32.02.7-1.61.6-1.6-1.31.3-1.31.3-1.5-1.5-1.51.51.51.6-1.61.6-1.21.1-1.11.2
BMI with tail6.522.526.4-4.94.9-4.8-5.15.1-5.15.1-4.8-4.8-4.84.84.84.6-4.64.6-4.74.2-4.53.3
BMI without tail1.15.97.8-2.72.6-2.5-2.82.8-2.82.8-2.3-2.3-2.32.42.42.3-2.32.3-2.52.2-2.31.3
Body weight1.04.24.9-2.12.1-2.1-2.22.2-2.22.2-2.1-2.1-2.12.12.11.9-1.91.9-2.02.0-1.91.5
Weight adjusted by age0.20.51.2-0.90.8-0.7-0.80.8-0.80.8-0.5-0.5-0.50.50.50.4-0.40.4-1.01.1-0.9-0.1
Bone surface0.61.23.90.8-0.50.22.0-2.02.0-2.0-0.4-0.4-0.40.30.30.3-0.30.30.3-1.5-0.02.0
Bone volume0.61.34.20.6-0.30.02.0-2.02.0-2.0-0.6-0.6-0.60.30.30.3-0.30.30.3-1.5-0.02.1
Breakpoint value in progressive ratio session2.74.98.42.1-2.22.21.8-1.81.8-1.82.22.22.2-2.2-2.2-2.22.2-2.22.7-2.92.8-1.9
Number of licking bursts0.00.10.7-0.40.2-0.1-0.60.6-0.60.60.10.10.1-0.2-0.2-0.20.2-0.2-0.10.40.1-0.8
Context. condit. distance diff. score0.20.30.5-0.60.5-0.5-0.70.7-0.70.7-0.1-0.1-0.10.70.70.6-0.60.6-0.60.4-0.50.2
Locomotion velocity, session 10.40.51.30.9-0.70.61.1-1.11.1-1.10.40.40.4-0.4-0.4-0.40.4-0.40.5-0.80.30.4
Locomotion distance, session 10.30.42.00.8-0.60.30.9-0.90.9-0.90.40.40.40.10.10.1-0.10.10.0-0.1-0.31.4
Locomotion velocity, session 23.34.06.72.6-2.42.22.6-2.62.6-2.62.12.12.1-1.7-1.7-1.51.5-1.51.9-1.21.5-0.2
Locomotion distance, session 21.41.94.41.9-1.61.42.1-2.12.1-2.11.01.01.0-1.1-1.1-1.01.0-1.01.1-1.00.70.6
Locomotion velocity, session 36.27.18.62.8-2.92.92.5-2.52.5-2.52.92.92.9-2.7-2.7-2.62.6-2.62.8-2.12.7-2.4
Locomotion distance, session 30.00.00.1-0.0-0.00.0-0.10.1-0.10.10.20.20.2-0.0-0.0-0.00.0-0.00.1-0.00.1-0.3
Stereotopy head waving bouts, day 34.85.77.52.7-2.72.62.5-2.52.5-2.52.52.52.5-2.5-2.5-2.22.2-2.22.5-1.92.3-1.4
Stereotopy head waving duration, day 35.97.38.93.0-3.02.92.7-2.72.7-2.72.82.82.8-2.9-2.9-2.52.5-2.52.9-2.32.8-1.9
Locomotion velocity, session 70.70.71.30.6-0.60.71.0-1.01.0-1.01.21.21.2-0.6-0.6-0.80.8-0.80.6-0.90.6-0.7
Locomotion distance, session 70.10.20.4-0.70.5-0.4-0.70.7-0.70.70.10.10.10.30.30.1-0.10.1-0.40.0-0.2-0.5
Stereotopy head waving bouts, day 70.10.10.70.2-0.1-0.00.4-0.40.4-0.4-0.3-0.3-0.30.10.10.4-0.40.4-0.0-0.7-0.10.8
Stereotopy head waving duration, day 70.40.51.40.8-0.70.51.1-1.11.1-1.10.10.10.1-0.4-0.4-0.20.2-0.20.5-1.20.30.6
Locomotion velocity, session 80.60.82.01.1-0.90.81.4-1.41.4-1.40.90.90.9-0.4-0.4-0.30.3-0.30.50.30.20.6
Locomotion distance, session 80.20.20.50.7-0.60.50.6-0.60.6-0.60.70.70.7-0.2-0.2-0.20.2-0.20.3-0.30.10.3
Degree of sensitization distance0.40.40.6-0.70.7-0.7-0.60.6-0.60.6-0.4-0.4-0.40.80.80.7-0.70.7-0.80.5-0.80.6
Degree of sensitization stereotypy1.71.93.0-1.31.3-1.4-0.90.9-0.90.9-1.7-1.7-1.71.41.41.6-1.61.6-1.40.3-1.41.6
Conditioned locomotion1.31.53.9-1.41.3-1.2-1.71.7-1.71.7-0.9-0.9-0.90.90.90.9-0.90.9-1.02.0-0.8-0.0
Cocaine response after cond. corrected3.75.58.8-2.92.7-2.5-3.03.0-3.03.0-2.0-2.0-2.02.12.12.1-2.12.1-2.22.2-1.90.6
Cocaine response after cond. not corrected3.95.69.3-2.92.7-2.5-3.03.0-3.03.0-2.0-2.0-2.02.22.22.2-2.22.2-2.31.8-1.90.6
Cocaine response before conditioning0.80.95.20.9-0.80.81.0-1.01.0-1.00.70.70.7-0.7-0.7-0.70.7-0.70.9-2.30.9-0.4
Saline control response0.10.20.5-0.50.4-0.4-0.70.7-0.70.7-0.4-0.4-0.40.20.20.2-0.20.20.0-0.30.2-0.1
Bone: connectivity density0.40.62.8-0.40.6-0.70.2-0.20.2-0.2-0.9-0.9-0.90.90.90.9-0.90.9-0.80.1-1.01.7
Bone: cortical apparent density0.71.11.8-1.21.2-1.2-0.90.9-0.90.9-1.4-1.4-1.41.11.11.1-1.11.1-1.00.5-0.80.9
Bone: cortical area0.40.71.8-0.70.8-0.90.1-0.10.1-0.1-1.1-1.1-1.11.01.01.0-1.01.0-0.7-0.1-0.81.4
Bone: cortical porosity0.20.20.60.4-0.30.20.8-0.80.8-0.80.20.20.2-0.2-0.2-0.20.2-0.20.1-0.20.00.4
Bone: cortical porosity0.20.21.00.2-0.0-0.10.7-0.70.7-0.7-0.2-0.2-0.20.20.20.2-0.20.2-0.1-0.2-0.31.0
Bone: cortical thickness1.01.62.7-1.31.4-1.4-0.70.7-0.70.7-1.6-1.6-1.61.51.51.4-1.41.4-1.20.3-1.21.6
Bone: cortical thickness0.10.10.9-0.10.00.1-0.20.2-0.20.20.20.20.2-0.4-0.4-0.40.4-0.40.2-0.50.4-0.9
Bone: cortical tissue density0.50.81.3-1.01.0-1.0-0.70.7-0.70.7-1.2-1.2-1.20.90.90.9-0.90.9-0.80.4-0.70.8
Condit. Reinf. active minus inactive responses4.24.75.92.4-2.42.42.1-2.12.1-2.12.32.32.3-2.2-2.2-2.12.1-2.12.3-1.42.2-1.8
Condit. Reinf. active-inactive response ratio2.22.33.41.5-1.61.71.2-1.21.2-1.21.61.61.6-1.6-1.6-1.61.6-1.61.6-1.21.7-1.9
Condit. Reinf. active responses3.34.26.12.5-2.42.32.3-2.32.3-2.32.02.02.0-2.0-2.0-1.91.9-1.92.1-1.11.9-1.0
Condit. Reinf. inactive responses0.60.81.91.3-1.10.91.4-1.41.4-1.40.70.70.7-0.5-0.5-0.60.6-0.60.6-0.20.30.5
Incentive salience index mean2.02.64.02.0-1.91.81.9-1.91.9-1.91.61.61.6-1.5-1.5-1.41.4-1.41.6-1.01.4-0.8
Condit. Reinf. lever presses0.20.31.90.5-0.30.10.8-0.80.8-0.8-0.3-0.3-0.30.30.30.3-0.30.3-0.10.1-0.41.4
Condit. Reinf. active minus inactive responses1.92.94.11.4-1.51.61.3-1.31.3-1.31.51.51.5-1.9-1.9-1.91.9-1.91.9-1.92.0-2.0
Condit. Reinf. active-inactive response ratio0.10.21.1-0.1-0.10.2-0.50.5-0.50.50.00.00.0-0.6-0.6-0.60.6-0.60.20.10.4-1.0
Condit. Reinf. active responses2.33.35.71.5-1.61.71.7-1.71.7-1.71.51.51.5-1.9-1.9-1.91.9-1.92.1-2.42.2-1.8
Condit. Reinf. inactive responses1.31.94.41.1-1.21.21.5-1.51.5-1.51.31.31.3-1.2-1.2-1.21.2-1.21.7-2.11.8-1.0
Condit. Reinf. lever presses1.82.74.51.4-1.51.61.3-1.31.3-1.31.51.51.5-1.8-1.8-1.81.8-1.81.9-2.12.0-1.8
Condit. Reinf. lever reinforcers received1.82.55.31.2-1.31.41.3-1.31.3-1.31.31.31.3-1.7-1.7-1.71.7-1.71.9-2.32.1-1.8
Conditioned reinforcement - actives0.31.32.61.0-1.11.20.8-0.80.8-0.81.41.41.4-1.0-1.0-1.51.5-1.50.6-0.20.5-1.6
Conditioned reinforcement - inactives0.00.10.2-0.20.1-0.1-0.50.5-0.50.50.00.00.00.30.30.0-0.00.0-0.40.5-0.4-0.3
Conditioned locomotion5.98.89.83.1-3.13.13.0-3.03.0-3.02.92.92.9-2.9-2.9-3.13.1-3.13.0-2.72.8-2.2
Patch foraging indifference point 0 sec0.10.30.6-0.50.6-0.6-0.20.2-0.20.2-0.7-0.7-0.70.60.60.5-0.50.5-0.50.1-0.60.8
Patch foraging indifference point AUC0.41.01.51.0-1.01.10.8-0.80.8-0.80.90.90.9-1.1-1.1-1.21.2-1.21.0-0.61.0-1.0
Delay disc. indifference point, 0s delay7.98.913.2-2.72.9-3.1-2.02.0-2.02.0-3.3-3.3-3.33.33.33.2-3.23.2-3.22.6-3.33.6
Delay disc. indifference point, 16s delay0.10.10.3-0.40.4-0.4-0.30.3-0.30.3-0.4-0.4-0.40.30.30.5-0.50.5-0.10.0-0.00.3
Delay disc. indifference point, 2s delay5.76.47.9-2.62.7-2.8-2.12.1-2.12.1-2.7-2.7-2.72.72.72.8-2.82.8-2.51.4-2.42.6
Delay disc. indifference point, 24s delay0.40.61.0-1.01.0-0.9-0.80.8-0.80.8-0.9-0.9-0.90.50.50.7-0.70.7-0.80.6-0.70.3
Delay disc. indifference point, 4s delay1.01.12.0-1.11.1-1.2-0.70.7-0.70.7-1.1-1.1-1.11.11.11.4-1.41.4-0.90.5-0.81.1
Delay disc. indifference point, 8s delay0.71.22.0-1.41.3-1.3-1.21.2-1.21.2-0.9-0.9-0.91.11.11.0-1.01.0-0.91.4-0.80.5
Indifference point function ln k0.00.10.3-0.50.5-0.5-0.30.3-0.30.3-0.3-0.3-0.30.50.50.4-0.40.4-0.4-0.1-0.30.0
Indifference point function log k0.00.10.3-0.50.5-0.5-0.30.3-0.30.3-0.3-0.3-0.30.50.50.4-0.40.4-0.4-0.1-0.30.0
Patch foraging total patch changes 0 sec0.10.20.4-0.40.5-0.5-0.20.2-0.20.2-0.5-0.5-0.50.50.50.5-0.50.5-0.40.2-0.50.6
Patch foraging total patch changes 12 sec0.40.61.4-0.80.7-0.7-1.21.2-1.21.2-0.6-0.6-0.60.50.50.5-0.50.5-0.80.8-0.80.2
Patch foraging total patch changes 18 sec0.51.11.31.1-1.11.11.1-1.11.1-1.10.90.90.9-1.1-1.1-1.11.1-1.11.1-1.11.1-0.7
Patch foraging total patch changes 24 sec0.00.11.20.3-0.30.20.3-0.30.3-0.30.00.00.0-0.3-0.3-0.30.3-0.30.6-1.10.60.1
Patch foraging total patch changes 6 sec0.10.20.40.5-0.50.40.7-0.70.7-0.70.30.30.3-0.5-0.5-0.50.5-0.50.40.10.3-0.0
Patch foraging time to switch 0 sec0.52.05.7-0.91.1-1.3-0.70.7-0.70.7-1.3-1.3-1.31.71.71.7-1.71.7-1.51.2-1.82.4
Patch foraging water rate 0 sec0.10.32.2-0.40.20.0-0.60.6-0.60.60.50.50.5-0.4-0.4-0.40.4-0.4-0.00.50.2-1.5
Patch foraging water rate 12 sec0.41.53.3-1.61.4-1.2-1.81.8-1.81.8-1.0-1.0-1.00.80.80.7-0.70.7-1.11.1-0.7-0.5
Patch foraging water rate 18 sec0.40.95.7-0.3-0.00.3-1.01.0-1.01.00.90.90.9-0.9-0.9-0.90.9-0.90.6-0.21.0-2.4
Patch foraging water rate 24 sec0.71.13.2-1.10.8-0.6-1.81.8-1.81.8-0.0-0.0-0.00.10.10.0-0.00.0-0.61.5-0.2-1.5
Patch foraging water rate 6 sec0.50.73.50.2-0.40.6-0.20.2-0.20.20.70.70.7-1.1-1.1-1.11.1-1.10.9-0.81.2-1.9
Seeking ratio, delayed vs. immediate footshock3.65.18.52.3-2.32.22.3-2.32.3-2.32.12.12.1-2.1-2.1-2.02.0-2.02.8-2.92.8-1.4
Distance traveled before self-admin0.10.20.5-0.40.5-0.5-0.10.1-0.10.1-0.6-0.6-0.60.70.70.4-0.40.4-0.3-0.0-0.30.7
Distance traveled after self-admin0.00.00.30.1-0.00.00.2-0.20.2-0.2-0.0-0.0-0.0-0.0-0.0-0.10.1-0.10.3-0.50.30.1
Extensor digitorum longus weight4.016.120.9-4.44.3-4.2-4.64.6-4.64.6-3.7-3.7-3.73.93.93.9-3.93.9-3.94.1-3.62.2
Bone: elastic displacement0.10.20.30.3-0.30.30.5-0.50.5-0.50.20.20.2-0.4-0.4-0.40.4-0.40.3-0.40.3-0.3
Bone: elastic work0.20.30.5-0.70.7-0.7-0.10.1-0.10.1-0.7-0.7-0.70.70.70.7-0.70.7-0.5-0.2-0.50.6
Bone: endosteal estimation0.10.30.6-0.50.5-0.6-0.30.3-0.30.3-0.5-0.5-0.50.70.70.8-0.80.8-0.50.5-0.50.5
Bone: endosteal perimeter0.30.61.40.9-0.80.71.2-1.21.2-1.20.60.60.6-0.6-0.6-0.50.5-0.50.6-0.90.5-0.1
Epididymis fat weight0.10.31.0-0.1-0.00.1-0.80.8-0.80.80.40.40.4-0.3-0.3-0.10.1-0.10.2-0.20.4-1.0
Delta time in closed arm before/after self-admin0.90.82.7-1.10.9-0.7-1.61.6-1.61.6-0.4-0.4-0.40.30.30.2-0.20.2-0.50.7-0.2-1.0
Delta time in open arm before/after self-admin0.50.61.0-0.70.7-0.7-0.70.7-0.70.7-0.7-0.7-0.70.70.70.8-0.80.8-0.81.0-0.70.6
Diff in mean of infusions in LGA sessions1.32.33.61.6-1.61.51.4-1.41.4-1.41.61.61.6-1.5-1.5-1.41.4-1.41.9-1.81.9-1.1
Delay discount exponential model param1.21.62.31.5-1.51.51.2-1.21.2-1.21.31.31.3-1.3-1.3-1.41.4-1.41.1-0.90.9-1.0
Extinction: sum of active levers before priming0.71.12.00.9-1.01.00.5-0.50.5-0.51.11.11.1-1.1-1.1-1.21.2-1.21.3-1.41.3-1.1
Active lever presses in extinction session 62.12.12.91.5-1.51.41.7-1.71.7-1.71.21.21.2-1.5-1.5-1.51.5-1.51.4-1.61.4-0.7
Bone: final force1.21.93.0-1.41.5-1.6-0.60.6-0.60.6-1.6-1.6-1.61.71.71.6-1.61.6-1.20.6-1.21.7
Bone: final moment1.01.52.4-1.31.4-1.4-0.50.5-0.50.5-1.5-1.5-1.51.51.51.5-1.51.5-1.10.7-1.11.6
Food consumed during 24 hour testing period0.30.61.0-1.00.9-0.9-0.80.8-0.80.8-0.6-0.6-0.60.80.80.8-0.80.8-0.60.8-0.50.3
Glucose2.64.15.2-2.32.2-2.2-2.12.1-2.12.1-2.2-2.2-2.22.02.02.0-2.02.0-2.01.5-1.91.4
Heart weight0.61.02.80.7-0.91.00.2-0.20.2-0.21.01.01.0-1.2-1.2-1.11.1-1.11.1-1.21.2-1.7
Delay discount hyperbolic model param2.32.93.92.0-2.02.01.5-1.51.5-1.51.81.81.8-1.8-1.8-1.91.9-1.91.5-1.11.4-1.5
Intermittent access intake day 1-15 change1.26.48.32.5-2.62.62.1-2.12.1-2.12.72.72.7-2.7-2.7-2.92.9-2.92.4-1.92.5-2.6
Intermittent access intake escalation1.05.67.22.3-2.42.52.0-2.02.0-2.02.52.52.5-2.5-2.5-2.72.7-2.72.3-1.62.3-2.5
Intermittent access intake escalation 23.05.16.32.2-2.32.32.0-2.02.0-2.02.32.32.3-2.4-2.4-2.52.5-2.52.3-1.92.3-2.2
Intermitt. access day 1 inactive lever presses0.00.31.60.0-0.20.3-0.40.4-0.40.40.60.60.6-0.5-0.5-0.70.7-0.70.20.00.3-1.3
Intermitt. access day 15 inactive lever presses0.10.40.60.8-0.70.70.7-0.70.7-0.70.70.70.7-0.6-0.6-0.60.6-0.60.40.00.3-0.4
Intermitt. access escalation Index0.31.12.3-0.80.9-1.0-0.30.3-0.30.3-1.2-1.2-1.21.21.21.1-1.11.1-1.21.3-1.31.5
Intermittent access day 1 total infusions0.10.20.80.2-0.30.4-0.00.0-0.00.00.60.60.6-0.4-0.4-0.50.5-0.50.1-0.40.2-0.9
Intermittent access day 15 total infusions1.43.44.31.8-1.92.01.6-1.61.6-1.62.02.02.0-2.0-2.0-2.12.1-2.11.7-1.51.6-2.0
Intermittent access terminal intake (last 3 days)1.32.22.81.5-1.51.61.3-1.31.3-1.31.71.71.7-1.6-1.6-1.71.7-1.71.2-1.31.1-1.5
Intermittent access total infusions0.81.01.51.0-1.01.10.8-0.80.8-0.81.21.21.2-1.1-1.1-1.21.2-1.20.6-0.50.5-1.2
Intermittent access day 1 locomotion1.01.83.81.2-1.41.40.6-0.60.6-0.61.71.71.7-1.4-1.4-1.51.5-1.51.3-1.11.4-1.9
Intermittent access day 15 total locomotion1.24.86.42.3-2.42.41.7-1.71.7-1.72.52.52.5-2.3-2.3-2.52.5-2.52.0-0.71.9-2.5
Intermittent access total locomotion2.22.63.51.6-1.71.71.2-1.21.2-1.21.91.91.9-1.6-1.6-1.81.8-1.81.5-0.91.5-1.9
Intermittent access standard deviation1.37.07.82.8-2.82.82.7-2.72.7-2.72.82.82.8-2.7-2.7-2.82.8-2.82.4-2.32.2-2.3
Left kidney weight0.00.20.8-0.30.1-0.0-0.60.6-0.60.60.50.50.50.00.0-0.20.2-0.20.00.60.2-0.9
Right kidney weight0.32.14.71.1-1.31.40.8-0.80.8-0.81.71.71.7-1.5-1.5-1.61.6-1.61.5-0.51.7-2.2
Cocaine induced anxiety0.51.52.81.5-1.31.21.7-1.71.7-1.70.90.90.9-0.9-0.9-1.01.0-1.01.2-1.51.00.1
Post-drug Anxiety1.31.53.91.5-1.31.21.5-1.51.5-1.50.90.90.9-0.9-0.9-0.70.7-0.71.5-2.01.40.2
Baseline Anxiety0.10.20.90.2-0.30.30.2-0.20.2-0.20.30.30.3-0.3-0.3-0.20.2-0.20.7-0.90.8-0.4
Tail length2.513.516.63.6-3.73.73.6-3.63.6-3.64.14.14.1-3.8-3.8-3.83.8-3.83.6-2.93.5-3.3
Length with tail1.98.410.62.9-3.03.02.7-2.72.7-2.73.33.33.3-3.0-3.0-3.03.0-3.02.9-2.22.9-2.5
Length without tail0.00.00.1-0.20.1-0.1-0.20.2-0.20.2-0.1-0.1-0.10.10.10.0-0.00.0-0.00.3-0.0-0.0
Times rat made contact with spout0.20.21.4-0.60.5-0.4-0.70.7-0.70.7-0.1-0.1-0.10.20.20.2-0.20.2-0.21.2-0.1-0.3
Lifetime Intake0.40.50.90.7-0.70.80.5-0.50.5-0.50.90.90.9-0.7-0.7-0.80.8-0.80.4-0.50.3-1.0
Liver weight, left0.91.51.9-1.31.3-1.2-1.41.4-1.41.4-1.3-1.3-1.31.21.21.3-1.31.3-1.11.0-1.00.6
Liver weight, right0.50.91.5-1.21.1-1.0-1.21.2-1.21.2-0.7-0.7-0.71.01.00.9-0.90.9-0.91.1-0.70.2
Locomotor activity3.25.19.42.3-2.22.02.9-2.92.9-2.91.71.71.7-2.0-2.0-2.02.0-2.02.4-3.12.2-0.5
Locomotor testing distance1.43.48.81.9-1.71.62.3-2.32.3-2.31.21.21.2-1.6-1.6-1.61.6-1.62.1-3.02.0-0.4
Locomotor testing rearing0.00.10.7-0.0-0.10.10.0-0.00.0-0.0-0.1-0.1-0.1-0.4-0.4-0.40.4-0.40.6-0.80.8-0.6
Locomotion in novel chamber0.81.11.71.0-1.01.10.8-0.80.8-0.81.01.01.0-1.1-1.1-1.31.3-1.31.2-0.71.3-1.1
Locomotion in novel chamber post-restriction0.92.66.81.3-1.41.41.4-1.41.4-1.41.61.61.6-1.4-1.4-1.51.5-1.51.9-2.62.1-1.5
Fecal boli incidents, locomotor time 10.71.82.6-1.41.4-1.4-1.61.6-1.61.6-1.1-1.1-1.11.41.41.2-1.21.2-1.31.4-1.31.1
Change in fecal boli incidents, locomotor task0.40.41.40.4-0.30.31.2-1.21.2-1.20.30.30.3-0.2-0.2-0.50.5-0.50.1-0.80.1-0.0
Time >=10cm from walls, locomotor time 10.60.82.2-0.60.8-0.90.0-0.00.0-0.0-1.1-1.1-1.11.01.00.7-0.70.7-1.11.1-1.21.5
Bouts of movement, locomotor time 10.30.40.80.6-0.60.60.5-0.50.5-0.50.90.90.9-0.5-0.5-0.70.7-0.70.30.40.3-0.7
Total resting periods, locomotor time 10.40.50.90.7-0.70.70.7-0.70.7-0.70.90.90.9-0.6-0.6-0.70.7-0.70.50.10.4-0.7
Rest time, locomotor task time 10.20.40.80.7-0.70.60.7-0.70.7-0.70.90.90.9-0.4-0.4-0.50.5-0.50.40.20.3-0.2
Distance moved, locomotor task time 10.41.12.5-0.91.0-1.1-0.20.2-0.20.2-1.4-1.4-1.41.01.01.0-1.01.0-1.30.6-1.41.6
Vertical activity count, locomotor time 10.00.30.6-0.80.7-0.7-0.30.3-0.30.3-0.8-0.8-0.80.40.40.3-0.30.3-0.50.2-0.4-0.0
Time >=10cm from walls, locomotor time 20.51.42.2-1.51.5-1.4-1.31.3-1.31.3-1.2-1.2-1.21.11.11.0-1.01.0-1.10.8-0.90.7
Bouts of movement, locomotor time 20.10.30.80.8-0.70.60.8-0.80.8-0.80.40.40.4-0.5-0.5-0.20.2-0.20.30.90.10.3
Total resting periods, locomotor time 20.10.30.90.8-0.70.60.8-0.80.8-0.80.40.40.4-0.4-0.4-0.10.1-0.10.20.90.00.4
Rest time, locomotor task time 20.40.71.31.0-0.90.91.1-1.11.1-1.10.80.80.8-0.8-0.8-0.70.7-0.70.8-0.40.6-0.2
Distance moved, locomotor task time 20.60.81.3-0.90.9-0.9-1.11.1-1.11.1-0.8-0.8-0.80.70.70.8-0.80.8-1.00.9-1.00.4
Vertical activity count, locomotor time 20.30.61.4-1.00.9-0.8-1.21.2-1.21.2-0.4-0.4-0.40.60.60.5-0.50.5-0.80.7-0.7-0.1
Light reinforcement 12.210.214.83.6-3.53.43.4-3.43.4-3.42.92.92.9-3.0-3.0-3.13.1-3.13.3-3.93.1-1.7
Light reinforcement 21.22.74.71.9-1.81.71.9-1.91.9-1.91.51.51.5-1.5-1.5-1.51.5-1.51.6-2.21.5-0.8
Bone: marrow area0.10.30.6-0.50.5-0.6-0.30.3-0.30.3-0.5-0.5-0.50.70.70.8-0.80.8-0.50.5-0.50.5
Bone: maximum diameter0.91.73.61.4-1.31.21.9-1.91.9-1.91.01.01.0-1.0-1.0-1.01.0-1.01.3-1.91.1-0.2
Bone: maximum force1.01.92.7-1.51.6-1.6-0.80.8-0.80.8-1.6-1.6-1.61.61.61.6-1.61.6-1.30.8-1.21.5
Bone: maximum moment0.91.62.3-1.41.4-1.5-0.70.7-0.70.7-1.5-1.5-1.51.51.51.5-1.51.5-1.20.8-1.11.3
Mean time between licks in bursts1.05.86.72.5-2.62.62.3-2.32.3-2.32.32.32.3-2.6-2.6-2.62.6-2.62.4-1.72.4-2.1
Mean num. licks in bursts0.00.10.2-0.10.1-0.20.0-0.00.0-0.0-0.1-0.1-0.10.30.30.3-0.30.3-0.10.4-0.10.4
Cd content in liver0.20.20.30.4-0.40.40.5-0.50.5-0.50.20.20.2-0.4-0.4-0.40.4-0.40.6-0.50.5-0.1
Co content in liver1.51.82.31.3-1.31.41.2-1.21.2-1.21.21.21.2-1.5-1.5-1.51.5-1.51.4-1.41.5-1.3
Cu content in liver0.20.30.90.6-0.50.40.9-0.90.9-0.90.30.30.3-0.2-0.2-0.20.2-0.20.2-0.00.00.5
Fe content in liver0.20.20.60.4-0.50.50.1-0.10.1-0.10.80.80.8-0.5-0.5-0.50.5-0.50.30.20.2-0.6
K content in liver0.10.10.50.3-0.20.10.5-0.50.5-0.5-0.2-0.2-0.20.10.10.1-0.10.10.1-0.2-0.00.7
Mg content in liver0.20.30.50.6-0.50.50.7-0.70.7-0.70.30.30.3-0.5-0.5-0.50.5-0.50.5-0.40.4-0.0
Mn content in liver1.51.74.71.5-1.31.22.2-2.22.2-2.21.11.11.1-0.8-0.8-0.80.8-0.80.9-0.70.60.3
Na content in liver0.91.12.9-0.70.9-1.0-0.50.5-0.50.5-1.1-1.1-1.11.21.21.2-1.21.2-1.10.9-1.31.7
Rb content in liver0.20.20.80.3-0.10.00.7-0.70.7-0.7-0.2-0.2-0.20.20.20.2-0.20.20.1-0.90.00.9
Se content in liver0.20.30.80.6-0.60.60.4-0.40.4-0.40.90.90.9-0.5-0.5-0.50.5-0.50.30.10.2-0.4
Sr content in liver0.00.00.1-0.20.1-0.1-0.30.3-0.30.30.00.00.0-0.0-0.0-0.00.0-0.0-0.00.10.1-0.3
Zn content in liver3.64.27.91.8-2.02.11.1-1.11.1-1.12.12.12.1-2.4-2.4-2.42.4-2.42.2-1.22.3-2.8
Bone: minimum diameter0.00.10.2-0.00.1-0.10.4-0.40.4-0.4-0.1-0.1-0.10.30.30.3-0.30.3-0.0-0.4-0.10.4
Time in familiar zone, hab. session 12.22.53.61.5-1.51.61.2-1.21.2-1.21.91.91.9-1.7-1.7-1.51.5-1.51.7-1.21.8-1.7
Time in novel zone, hab. session 11.21.32.4-1.01.1-1.2-0.40.4-0.40.4-1.5-1.5-1.51.31.31.2-1.21.2-1.40.3-1.41.6
Total zone transitions, hab. session 10.81.12.41.4-1.21.01.5-1.51.5-1.50.70.70.7-0.9-0.9-0.70.7-0.70.8-0.90.50.5
Total locomotion distance, hab. session 11.11.64.01.6-1.41.22.0-2.02.0-2.00.90.90.9-0.9-0.9-0.70.7-0.71.0-1.40.60.7
Locomotion velocity, hab. session 11.52.14.21.9-1.71.52.1-2.12.1-2.11.21.21.2-1.2-1.2-1.01.0-1.01.3-1.10.90.4
Time in familiar zone, hab. session 26.16.98.62.6-2.72.82.0-2.02.0-2.02.82.82.8-2.8-2.8-2.82.8-2.82.8-2.12.8-2.9
Time in novel zone, hab. session 24.65.06.3-2.22.4-2.4-1.61.6-1.61.6-2.4-2.4-2.42.42.42.4-2.42.4-2.32.1-2.42.5
Total zone transitions, hab. session 20.60.74.80.00.2-0.50.3-0.30.3-0.3-0.8-0.8-0.80.80.80.9-0.90.9-0.81.0-1.12.2
Total locomotion distance, hab. session 20.91.22.41.6-1.41.21.5-1.51.5-1.51.01.01.0-1.0-1.0-0.70.7-0.71.0-0.50.70.4
Locomotion velocity, hab. session 20.91.22.51.6-1.31.11.6-1.61.6-1.60.90.90.9-0.9-0.9-0.60.6-0.60.9-0.20.50.8
Novel to familiar place preference ratio3.84.97.0-2.12.2-2.3-1.41.4-1.41.4-2.5-2.5-2.52.52.52.4-2.42.4-2.51.7-2.62.7
Novelty place preference2.33.04.9-1.61.7-1.8-1.01.0-1.01.0-2.0-2.0-2.02.02.01.9-1.91.9-2.01.4-2.12.2
Time in novel zone, NPP test2.73.34.8-1.71.8-1.9-1.11.1-1.11.1-2.0-2.0-2.02.12.12.0-2.02.0-2.11.4-2.22.2
Total zone transitions, NPP test0.10.22.00.3-0.1-0.10.2-0.20.2-0.2-0.4-0.4-0.40.20.20.4-0.40.4-0.30.3-0.51.4
Total locomotion distance, NPP test0.10.21.80.3-0.1-0.10.4-0.40.4-0.4-0.4-0.4-0.40.20.20.5-0.50.5-0.20.3-0.41.3
Locomotion velocity, NPP test0.10.21.30.6-0.40.20.6-0.60.6-0.6-0.1-0.1-0.1-0.1-0.10.2-0.20.20.10.2-0.21.1
Intraocular pressure0.20.31.7-0.30.10.0-0.90.9-0.90.90.30.30.3-0.3-0.3-0.40.4-0.40.40.20.6-1.3
Delta distance traveled before/after self-admin0.50.61.40.7-0.70.70.5-0.50.5-0.50.80.80.8-0.8-0.8-0.70.7-0.70.9-1.20.9-0.7
Delta ambulatory time before/after self-admin0.30.50.80.7-0.70.70.6-0.60.6-0.60.80.80.8-0.7-0.7-0.60.6-0.60.7-0.90.7-0.5
Parametrial fat weight0.00.00.20.1-0.0-0.00.1-0.10.1-0.1-0.1-0.1-0.10.20.20.1-0.10.1-0.10.2-0.20.4
Pavlov. Cond. lever latency0.10.21.1-0.40.2-0.1-0.60.6-0.60.6-0.2-0.2-0.2-0.1-0.1-0.30.3-0.3-0.0-0.40.2-1.1
Pavlov. Cond. magazine entry latency3.24.16.22.3-2.32.21.8-1.81.8-1.82.52.52.5-2.0-2.0-2.02.0-2.02.1-1.11.9-1.6
Pavlov. Cond. change in total contacts0.10.10.30.4-0.40.30.2-0.20.2-0.20.50.50.5-0.2-0.2-0.20.2-0.20.20.10.10.0
Pavlov. Cond. index score0.50.71.31.0-1.00.90.9-0.90.9-0.91.21.21.2-0.7-0.7-0.50.5-0.50.8-0.10.6-0.1
Pavlov. Cond. latency score0.50.61.11.0-0.90.81.0-1.01.0-1.01.11.11.1-0.6-0.6-0.40.4-0.40.7-0.10.50.2
Pavlov. Cond. lever contacts0.10.10.90.3-0.20.00.5-0.50.5-0.50.20.20.20.10.10.3-0.30.3-0.00.5-0.31.0
Pavlov. Cond. magazine entry number0.91.22.2-1.21.2-1.2-0.80.8-0.80.8-1.5-1.5-1.51.11.11.0-1.01.0-1.10.1-1.00.9
Pavlov. Cond. intertrial magazine entries0.20.21.00.2-0.30.4-0.10.1-0.10.10.30.30.3-0.6-0.6-0.60.6-0.60.6-0.10.7-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.81.61.1-1.11.01.0-1.01.0-1.01.31.31.3-0.8-0.8-0.60.6-0.60.9-0.20.7-0.2
Pavlov. Cond. response bias0.91.22.21.2-1.21.20.9-0.90.9-0.91.51.51.5-1.1-1.1-1.01.0-1.01.1-0.21.0-0.8
Pavlov. Cond. lever latency0.81.12.0-0.80.8-0.9-1.21.2-1.21.2-0.8-0.8-0.81.11.11.1-1.11.1-1.21.4-1.31.0
Pavlov. Cond. magazine entry latency0.40.50.70.7-0.70.70.8-0.80.8-0.80.80.80.8-0.7-0.7-0.70.7-0.70.6-0.80.6-0.7
Pavlov. Cond. change in total contacts0.30.81.60.7-0.70.80.9-0.90.9-0.90.60.60.6-1.0-1.0-1.01.0-1.01.0-1.31.1-1.0
Pavlov. Cond. index score0.60.91.40.7-0.80.81.0-1.01.0-1.00.90.90.9-1.0-1.0-1.01.0-1.01.0-1.21.1-1.0
Pavlov. Cond. latency score0.60.91.30.8-0.80.81.1-1.11.1-1.10.80.80.8-1.0-1.0-1.01.0-1.01.0-1.11.0-0.8
Pavlov. Cond. lever contacts0.60.91.80.6-0.70.80.9-0.90.9-0.90.80.80.8-1.0-1.0-1.01.0-1.01.1-1.31.2-1.1
Pavlov. Cond. magazine entry number0.70.91.3-0.90.9-0.9-1.11.1-1.11.1-1.0-1.0-1.00.90.90.9-0.90.9-0.91.1-0.80.8
Pavlov. Cond. intertrial magazine entries0.20.40.8-0.80.7-0.6-0.90.9-0.90.9-0.6-0.6-0.60.50.50.5-0.50.5-0.2-0.20.1-0.0
Pavlov. Cond. lever-magazine prob. diff.0.71.01.60.8-0.80.91.1-1.11.1-1.10.90.90.9-1.0-1.0-1.01.0-1.01.0-1.31.0-0.9
Pavlov. Cond. response bias1.72.33.31.2-1.31.41.4-1.41.4-1.41.41.41.4-1.6-1.6-1.61.6-1.61.7-1.71.8-1.7
Time in closed arm before self-admin0.30.51.9-0.40.6-0.7-0.20.2-0.20.2-0.7-0.7-0.71.01.00.9-0.90.9-0.40.1-0.51.4
Time in closed arm after self-admin0.40.42.00.3-0.40.40.1-0.10.1-0.10.50.50.5-0.6-0.6-0.60.6-0.61.0-1.41.2-0.8
Time in open arm before self-admin0.10.10.20.3-0.30.30.5-0.50.5-0.50.20.20.2-0.2-0.2-0.40.4-0.4-0.1-0.1-0.1-0.1
Time in open arm after self-admin1.31.44.1-1.11.1-1.1-1.01.0-1.01.0-1.1-1.1-1.11.11.11.1-1.11.1-1.52.0-1.60.8
Bone: periosteal estimation0.20.51.3-0.50.6-0.70.1-0.10.1-0.1-0.8-0.8-0.80.90.90.9-0.90.9-0.6-0.0-0.61.1
Bone: periosteal perimeter0.20.31.10.5-0.40.31.1-1.11.1-1.10.10.10.1-0.1-0.1-0.10.1-0.10.4-0.80.20.5
Bone: post-yield work0.40.81.1-1.01.0-1.0-0.90.9-0.90.9-0.7-0.7-0.70.90.90.9-0.90.9-0.81.0-0.70.5
Progressive ratio test 1 active lever presses0.10.21.30.1-0.20.3-0.30.3-0.30.30.60.60.6-0.4-0.4-0.40.4-0.4-0.10.00.0-1.1
Progressive ratio test 1 breakpoint0.10.21.20.0-0.20.3-0.30.3-0.30.30.60.60.6-0.4-0.4-0.40.4-0.4-0.1-0.0-0.0-1.1
Progressive ratio test 1 inactive lever presses0.10.30.80.6-0.60.70.2-0.20.2-0.20.80.80.8-0.5-0.5-0.70.7-0.70.5-0.30.5-0.9
Progressive ratio test 2 active lever presses0.20.31.80.2-0.40.5-0.10.1-0.10.10.70.70.7-0.5-0.5-0.70.7-0.7-0.10.5-0.1-1.3
Progressive ratio test 2 breakpoint0.30.42.00.3-0.40.5-0.10.1-0.10.10.80.80.8-0.6-0.6-0.80.8-0.8-0.10.5-0.0-1.4
Progressive ratio test 2 inactive lever presses0.00.10.20.4-0.40.40.2-0.20.2-0.20.40.40.4-0.2-0.2-0.40.4-0.4-0.20.3-0.3-0.3
Incentive Sensitization - Responses0.10.42.7-0.30.2-0.1-0.70.7-0.70.70.10.10.10.20.2-0.20.2-0.2-0.71.6-0.7-0.7
Incentive Sensitization - Breakpoint0.10.32.3-0.20.10.0-0.60.6-0.60.60.20.20.20.10.1-0.30.3-0.3-0.61.5-0.6-0.7
Sum of active levers in priming session hrs 5-60.10.11.0-0.10.1-0.2-0.10.1-0.10.1-0.2-0.2-0.20.10.10.1-0.10.10.3-1.00.40.2
Progressive ratio0.30.85.1-0.50.5-0.4-1.31.3-1.31.3-0.3-0.3-0.30.40.40.6-0.60.6-0.92.3-0.90.1
Food seeking constrained by brief footshock0.20.20.60.8-0.70.60.2-0.20.2-0.20.80.80.8-0.3-0.3-0.40.4-0.40.5-0.10.4-0.0
Seeking ratio, punishment vs. effort0.30.73.60.8-0.70.61.0-1.01.0-1.00.60.60.6-0.5-0.5-0.60.6-0.61.0-1.91.00.0
Retroperitoneal fat weight0.41.94.2-1.41.3-1.2-2.12.1-2.12.1-0.9-0.9-0.91.01.01.1-1.11.1-1.21.8-1.00.1
Reaction time number correct0.20.72.4-1.10.9-0.7-1.31.3-1.31.3-0.3-0.3-0.30.40.40.4-0.40.4-0.61.5-0.4-0.7
Reaction time mean minus median0.10.71.00.7-0.80.80.7-0.70.7-0.70.90.90.9-0.9-0.9-0.90.9-0.90.8-0.80.8-1.0
Reaction time mean minus median AUC0.00.10.30.00.0-0.10.5-0.50.5-0.5-0.0-0.0-0.00.30.30.3-0.30.3-0.20.2-0.30.5
Reaction time num false alarms0.10.21.2-0.70.6-0.5-0.50.5-0.50.5-0.2-0.2-0.20.20.20.2-0.20.2-0.51.1-0.4-0.5
Reaction time num false alarms AUC0.10.31.5-0.70.6-0.5-0.70.7-0.70.7-0.2-0.2-0.20.20.20.2-0.20.2-0.61.2-0.4-0.7
Reaction time trials correct on left0.20.72.4-1.10.9-0.7-1.31.3-1.31.3-0.3-0.3-0.30.40.40.4-0.40.4-0.61.5-0.4-0.7
Reaction time trials on left0.20.72.4-1.10.9-0.7-1.21.2-1.21.2-0.4-0.4-0.40.50.50.5-0.50.5-0.71.6-0.4-0.7
Reaction time mean0.00.10.2-0.20.3-0.30.2-0.20.2-0.2-0.3-0.3-0.30.30.30.3-0.30.3-0.30.2-0.40.5
Reaction time mean AUC0.00.10.3-0.30.3-0.30.2-0.20.2-0.2-0.4-0.4-0.40.40.40.3-0.30.3-0.40.2-0.40.5
Median of all reaction times0.30.40.9-0.60.7-0.7-0.10.1-0.10.1-0.7-0.7-0.70.80.80.7-0.70.7-0.80.5-0.80.9
Reaction time omissions0.10.10.40.5-0.40.30.6-0.60.6-0.60.10.10.1-0.1-0.1-0.20.2-0.20.40.10.30.3
Reaction time false alarm rate0.00.00.1-0.30.3-0.3-0.10.1-0.10.1-0.2-0.2-0.20.20.20.2-0.20.2-0.40.2-0.40.1
Reaction time premature initiation rate0.81.32.01.0-1.11.20.8-0.80.8-0.81.21.21.2-1.3-1.3-1.31.3-1.31.2-1.11.2-1.4
Reaction time premature initiations0.31.03.70.6-0.70.90.2-0.20.2-0.21.11.11.1-1.2-1.2-1.21.2-1.20.9-0.31.1-1.9
Std. dev. reaction times0.00.10.30.3-0.30.30.5-0.50.5-0.50.40.40.4-0.3-0.3-0.40.4-0.40.3-0.30.3-0.3
Reaction time trials completed0.20.72.4-1.10.9-0.7-1.21.2-1.21.2-0.4-0.4-0.40.50.50.5-0.50.5-0.71.6-0.4-0.7
Reaction time trials AUC0.20.82.8-1.10.9-0.7-1.31.3-1.31.3-0.3-0.3-0.30.40.40.4-0.40.4-0.61.7-0.4-0.9
Run reversals in cocaine runway, females0.60.61.00.9-0.90.81.0-1.01.0-1.00.80.80.8-0.6-0.6-0.50.5-0.50.9-0.90.8-0.2
Run reversals in cocaine runway, males2.12.36.21.5-1.51.41.7-1.71.7-1.71.31.31.3-1.3-1.3-1.21.2-1.21.9-2.51.9-0.7
Latency to leave start box in cocaine runway0.40.51.40.7-0.60.51.2-1.21.2-1.2-0.1-0.1-0.1-0.4-0.4-0.30.3-0.30.5-1.10.40.5
Latency to leave start box in cocaine runway, F0.40.52.3-0.00.3-0.40.8-0.80.8-0.8-1.0-1.0-1.00.60.60.5-0.50.5-0.4-0.6-0.61.5
Latency to leave start box in cocaine runway, M1.71.72.21.3-1.31.40.9-0.90.9-0.91.41.41.4-1.4-1.4-1.31.3-1.31.4-1.11.5-1.5
Std. dev. time between licks in bursts0.50.92.20.9-0.90.91.5-1.51.5-1.50.70.70.7-0.8-0.8-0.80.8-0.80.7-0.20.6-0.5
Total sessions with >9 infusions0.20.30.80.3-0.40.50.2-0.20.2-0.20.70.70.7-0.4-0.4-0.70.7-0.70.4-0.70.4-0.9
Short access day 1 total inactive lever presses0.20.30.60.6-0.70.70.3-0.30.3-0.30.80.80.8-0.5-0.5-0.70.7-0.70.20.40.1-0.7
Short access day 10 total inactive lever presses0.00.10.3-0.20.1-0.1-0.50.5-0.50.50.00.00.0-0.2-0.2-0.20.2-0.2-0.10.5-0.0-0.4
Short access day 1 total infusions0.20.40.60.7-0.70.70.5-0.50.5-0.50.80.80.8-0.5-0.5-0.60.6-0.60.4-0.60.3-0.6
Short access day 10 total infusions0.10.10.70.1-0.30.3-0.20.2-0.20.20.50.50.5-0.3-0.3-0.30.3-0.30.0-0.20.1-0.9
Short access total infusions0.20.30.60.5-0.50.60.3-0.30.3-0.30.70.70.7-0.5-0.5-0.60.6-0.60.2-0.40.2-0.8
Short access day 1 locomotion1.11.73.31.3-1.31.31.1-1.11.1-1.11.41.41.4-1.1-1.1-1.41.4-1.41.4-1.81.4-1.3
Short access day 10 total locomotion1.87.210.12.5-2.72.82.0-2.02.0-2.03.03.03.0-2.8-2.8-3.13.1-3.12.6-2.22.6-3.2
Short access total locomotion1.82.84.81.5-1.61.71.3-1.31.3-1.31.81.81.8-1.5-1.5-1.91.9-1.91.7-2.21.8-1.8
One hour access (0.3 mA shock)0.10.10.4-0.20.1-0.1-0.30.3-0.30.30.10.10.10.20.20.1-0.10.1-0.50.6-0.6-0.3
Compulsive drug intake1.01.43.6-1.01.1-1.2-0.40.4-0.40.4-1.5-1.5-1.51.51.51.4-1.41.4-1.00.8-1.11.9
One hour access (shock baseline)0.20.62.30.6-0.80.90.3-0.30.3-0.31.11.11.1-0.9-0.9-0.90.9-0.90.3-0.30.4-1.5
Social response proportion0.60.71.31.1-1.01.01.1-1.11.1-1.10.70.70.7-0.9-0.9-0.80.8-0.80.60.20.4-0.2
Social responses6.68.611.43.1-3.13.03.4-3.43.4-3.42.62.62.6-2.9-2.9-2.92.9-2.92.9-2.92.7-1.7
Social time0.40.71.4-0.70.8-0.8-0.90.9-0.90.9-1.2-1.2-1.20.70.70.7-0.70.7-0.70.2-0.60.8
Soleus weight7.923.227.4-5.25.2-5.2-4.74.7-4.74.7-5.0-5.0-5.05.15.15.0-5.05.0-4.73.8-4.43.7
Bone: stiffness2.24.05.1-2.02.1-2.2-1.51.5-1.51.5-2.2-2.2-2.22.32.32.2-2.22.2-2.01.3-2.02.0
Tibialis anterior weight1.03.44.0-2.02.0-2.0-1.91.9-1.91.9-1.8-1.8-1.81.91.92.0-2.02.0-1.61.6-1.51.3
Time to tail flick, vehicle, before self-admin0.20.32.80.3-0.30.30.3-0.30.3-0.30.20.20.2-0.2-0.2-0.00.0-0.01.0-1.71.00.1
Time to tail flick, vehicle, after self-admin0.30.62.40.4-0.60.7-0.10.1-0.10.10.90.90.9-1.0-1.0-0.90.9-0.90.6-0.70.8-1.5
Time to tail flick, test, before self-admin0.40.41.10.6-0.50.51.0-1.01.0-1.00.30.30.3-0.2-0.2-0.50.5-0.50.4-0.90.30.1
Time to tail flick, test, after self-admin0.20.20.60.4-0.40.40.3-0.30.3-0.30.50.50.5-0.4-0.4-0.30.3-0.30.7-0.80.7-0.3
Delta time to tail flick, vehicle, before/after SA0.40.41.2-0.50.4-0.3-1.01.0-1.01.0-0.0-0.0-0.0-0.0-0.00.0-0.00.0-0.71.1-0.5-0.8
Delta time to tail flick, test, before/after SA0.10.20.8-0.1-0.00.1-0.60.6-0.60.60.40.40.4-0.3-0.3-0.10.1-0.10.30.30.4-0.9
Tibia length0.72.02.91.5-1.51.51.4-1.41.4-1.41.31.31.3-1.7-1.7-1.61.6-1.61.4-0.81.3-1.3
Ambulatory time before self-admin0.10.20.4-0.50.5-0.5-0.20.2-0.20.2-0.6-0.6-0.60.60.60.4-0.40.4-0.30.1-0.30.6
Ambulatory time after self-admin0.00.00.2-0.00.0-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.10.0-0.00.00.2-0.50.20.3
Bone: tissue strength2.02.12.8-1.41.5-1.5-1.21.2-1.21.2-1.7-1.7-1.71.51.51.5-1.51.5-1.41.6-1.41.5
Total heroin consumption1.72.04.81.5-1.41.41.4-1.41.4-1.41.21.21.2-1.3-1.3-1.31.3-1.31.7-2.21.7-0.7
Bone: trabecular number0.40.82.41.0-0.80.71.4-1.41.4-1.40.60.60.6-0.4-0.4-0.40.4-0.40.6-1.50.40.4
Bone: trabecular spacing0.60.82.8-1.00.8-0.6-1.71.7-1.71.7-0.2-0.2-0.20.10.10.2-0.20.2-0.31.0-0.0-1.1
Bone: trabecular thickness0.81.15.60.10.2-0.41.5-1.51.5-1.5-0.9-0.9-0.90.70.70.7-0.70.7-0.4-0.1-0.82.4
Bone: trabecular tissue density1.22.14.3-1.51.4-1.4-1.71.7-1.71.7-1.3-1.3-1.31.31.31.3-1.31.3-1.32.1-1.20.8
Water consumed over 24 hours0.40.71.2-1.01.0-1.0-0.50.5-0.50.5-0.9-0.9-0.91.11.11.1-1.11.1-0.60.2-0.51.1
Number of responses in last shaping day1.41.82.71.2-1.31.40.9-0.90.9-0.91.61.61.6-1.3-1.3-1.41.4-1.41.3-1.31.4-1.6