Hub : Genes

Mgat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Mgat3 0.08 0.04 1.9e-06 0.04 0.06 0.06 0.05 3.5e-04 9.0e-06 1.0e-05 7.7e-05
2 Brain gene expression Mgat3 0.05 0.04 8.2e-03 0.01 0 0 0.02 3.1e-02 1.4e-01 1.9e-01 9.1e-03
3 IL gene expression Mgat3 0.23 0.12 3.0e-03 0.13 0.07 0.06 0.09 5.7e-04 1.0e-02 1.4e-02 2.9e-03
4 BLA gene expression Mgat3 0.12 0.08 5.2e-04 0.04 0.05 0.04 0.04 2.0e-03 1.1e-03 5.8e-03 2.9e-03
5 Adipose gene expression Mgat3 0.08 0.04 2.5e-06 0.04 0.02 0.01 0.03 1.6e-05 1.7e-03 8.4e-03 3.1e-04
6 NAcc intron excision ratio chr7_113599867_113637574 0.02 0.01 1.5e-03 0.01 0.01 0.01 0.01 2.0e-03 2.1e-03 2.6e-03 1.7e-03
7 PL gene expression Mgat3 0.05 0.04 6.1e-04 0.02 0.02 0.03 0.02 2.2e-03 5.1e-03 2.5e-04 4.9e-03
8 Brain mRNA stability Mgat3 0.11 0.08 4.3e-04 0.04 0.02 0.04 0.03 2.2e-04 3.9e-03 2.2e-04 1.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.30.70.30.60.60.60.5-0.50.90.0
Area under the delay curve1.72.04.02.00.70.71.31.6-1.81.5-1.2
BMI with tail0.82.85.3-2.3-1.9-1.9-1.9-1.31.6-1.40.4
BMI without tail0.10.31.1-1.1-0.3-0.3-0.2-0.20.2-0.60.7
Body weight1.77.39.8-3.1-2.9-2.9-2.6-2.92.7-3.1-0.6
Weight adjusted by age0.10.10.20.10.30.30.2-0.00.3-0.30.4
Bone surface0.20.30.60.80.60.60.70.3-0.40.1-0.8
Bone volume0.00.10.20.20.20.20.30.3-0.20.2-0.4
Breakpoint value in progressive ratio session0.10.10.4-0.1-0.2-0.2-0.2-0.20.1-0.6-0.3
Number of licking bursts0.81.32.31.51.21.21.41.0-1.20.5-0.4
Context. condit. distance diff. score6.78.112.3-3.5-3.0-3.0-3.2-2.63.2-2.41.0
Locomotion velocity, session 10.50.63.01.00.10.10.4-0.5-0.1-0.5-1.7
Locomotion distance, session 13.24.18.73.01.71.72.32.2-2.31.2-1.3
Locomotion velocity, session 20.20.20.5-0.2-0.5-0.5-0.6-0.60.3-0.4-0.7
Locomotion distance, session 24.05.59.83.12.02.02.52.4-2.91.8-1.7
Locomotion velocity, session 30.91.12.2-1.2-0.8-0.8-1.0-0.81.5-1.30.7
Locomotion distance, session 30.50.61.20.90.80.80.91.1-0.5-0.20.6
Stereotopy head waving bouts, day 30.91.02.4-0.6-0.9-0.9-0.8-1.50.9-0.9-1.2
Stereotopy head waving duration, day 33.23.97.5-1.9-1.9-1.9-2.0-2.72.0-1.6-1.2
Locomotion velocity, session 71.21.32.9-0.9-0.8-0.8-1.1-1.71.5-1.40.1
Locomotion distance, session 70.30.31.00.4-0.2-0.2-0.0-1.00.2-0.6-1.0
Stereotopy head waving bouts, day 73.33.76.5-2.4-1.5-1.5-2.1-2.02.6-2.00.7
Stereotopy head waving duration, day 72.93.57.1-2.7-1.4-1.4-2.2-1.62.4-1.51.3
Locomotion velocity, session 82.22.74.8-1.2-1.7-1.7-1.5-2.21.5-1.8-1.1
Locomotion distance, session 80.50.71.3-1.2-0.9-0.9-1.0-0.30.8-0.10.7
Degree of sensitization distance1.92.04.6-1.4-1.5-1.5-1.5-2.11.2-0.5-0.8
Degree of sensitization stereotypy2.42.64.4-2.1-1.4-1.4-1.9-1.32.0-1.60.8
Conditioned locomotion0.40.50.7-0.7-0.8-0.8-0.7-0.80.7-0.20.1
Cocaine response after cond. corrected0.10.10.40.0-0.4-0.4-0.3-0.30.1-0.0-0.6
Cocaine response after cond. not corrected0.00.00.1-0.1-0.1-0.1-0.20.00.10.3-0.1
Cocaine response before conditioning0.30.41.3-0.00.80.80.30.5-0.10.51.1
Saline control response0.40.52.0-0.50.50.5-0.0-0.40.60.61.4
Bone: connectivity density0.00.10.20.10.20.20.3-0.40.10.0-0.3
Bone: cortical apparent density0.40.51.00.41.01.00.80.5-0.20.11.0
Bone: cortical area0.91.32.4-0.8-1.5-1.5-1.2-0.90.7-0.7-1.4
Bone: cortical porosity0.70.81.5-1.2-0.7-0.7-1.1-1.10.90.20.5
Bone: cortical porosity1.71.93.2-1.6-1.4-1.4-1.7-1.81.4-0.6-0.2
Bone: cortical thickness0.20.30.90.1-0.8-0.8-0.30.0-0.10.4-1.0
Bone: cortical thickness0.70.93.20.9-0.6-0.60.20.8-1.00.4-1.8
Bone: cortical tissue density0.30.40.90.40.90.90.70.4-0.10.00.9
Condit. Reinf. active minus inactive responses0.20.20.40.60.60.60.60.2-0.5-0.1-0.5
Condit. Reinf. active-inactive response ratio0.20.20.4-0.4-0.3-0.3-0.4-0.50.6-0.60.1
Condit. Reinf. active responses1.51.83.21.01.81.81.51.5-1.40.70.4
Condit. Reinf. inactive responses2.63.15.31.12.32.31.82.2-1.71.01.0
Incentive salience index mean0.50.60.80.80.90.90.90.7-0.80.3-0.2
Condit. Reinf. lever presses0.60.81.40.71.21.21.01.1-0.90.50.2
Condit. Reinf. active minus inactive responses0.60.83.81.30.10.10.50.3-0.7-0.6-1.9
Condit. Reinf. active-inactive response ratio0.50.63.10.5-0.3-0.3-0.0-0.0-0.3-0.9-1.8
Condit. Reinf. active responses0.60.83.40.6-0.5-0.5-0.3-0.50.2-1.3-1.9
Condit. Reinf. inactive responses0.50.61.20.2-0.7-0.7-0.6-1.00.7-1.0-1.1
Condit. Reinf. lever presses0.50.71.30.90.80.80.91.1-1.00.2-0.2
Condit. Reinf. lever reinforcers received0.40.52.50.6-0.2-0.2-0.1-0.40.1-1.0-1.6
Conditioned reinforcement - actives0.30.51.81.3-0.1-0.10.20.4-0.6-0.3-1.3
Conditioned reinforcement - inactives1.42.14.72.20.90.91.61.0-1.90.6-1.6
Conditioned locomotion0.40.52.80.3-0.8-0.8-0.4-0.2-0.2-0.1-1.7
Patch foraging indifference point 0 sec0.40.71.50.41.11.10.90.3-0.81.20.2
Patch foraging indifference point AUC1.52.25.82.40.90.91.70.9-1.51.0-1.8
Delay disc. indifference point, 0s delay0.30.30.6-0.7-0.8-0.8-0.7-0.10.20.5-0.3
Delay disc. indifference point, 16s delay2.62.95.62.41.31.31.71.7-2.11.7-0.8
Delay disc. indifference point, 2s delay1.11.23.41.40.00.00.51.9-1.41.2-1.1
Delay disc. indifference point, 24s delay1.11.24.01.80.20.21.10.0-1.00.4-2.0
Delay disc. indifference point, 4s delay1.01.12.01.30.30.30.81.3-1.41.1-1.1
Delay disc. indifference point, 8s delay1.82.14.12.01.01.01.61.3-1.81.5-0.8
Indifference point function ln k1.73.06.7-2.6-1.5-1.5-2.1-1.32.0-0.81.5
Indifference point function log k1.73.06.7-2.6-1.5-1.5-2.1-1.32.0-0.81.5
Patch foraging total patch changes 0 sec0.71.23.10.61.31.31.20.8-1.11.80.3
Patch foraging total patch changes 12 sec0.20.30.60.70.50.50.40.0-0.30.8-0.8
Patch foraging total patch changes 18 sec0.81.22.81.40.90.91.20.1-1.20.7-1.7
Patch foraging total patch changes 24 sec0.50.91.51.21.11.11.10.1-0.71.1-0.5
Patch foraging total patch changes 6 sec1.62.53.71.91.31.31.90.7-1.71.8-1.6
Patch foraging time to switch 0 sec0.10.30.6-0.70.10.1-0.8-0.40.5-0.60.5
Patch foraging water rate 0 sec0.20.40.90.50.30.30.90.4-0.80.9-0.4
Patch foraging water rate 12 sec0.30.72.00.00.80.80.70.7-0.61.41.1
Patch foraging water rate 18 sec0.71.12.20.91.21.21.50.8-1.10.9-0.0
Patch foraging water rate 24 sec0.30.41.3-1.1-0.3-0.3-0.4-0.80.7-0.30.6
Patch foraging water rate 6 sec0.81.22.30.51.51.51.20.7-0.40.81.4
Seeking ratio, delayed vs. immediate footshock0.60.71.00.60.90.90.91.0-0.91.00.6
Distance traveled before self-admin0.50.71.90.80.60.60.51.2-0.91.4-0.1
Distance traveled after self-admin0.70.81.51.10.80.81.10.2-1.20.3-1.2
Extensor digitorum longus weight0.83.29.90.71.11.11.32.7-1.73.11.3
Bone: elastic displacement0.10.10.3-0.3-0.3-0.3-0.2-0.60.4-0.4-0.0
Bone: elastic work1.41.93.2-1.3-1.8-1.8-1.5-1.31.1-0.6-1.0
Bone: endosteal estimation0.51.12.2-0.8-0.8-0.8-1.1-1.20.9-1.5-1.1
Bone: endosteal perimeter1.22.63.6-1.7-1.6-1.6-1.9-1.71.7-1.7-0.6
Epididymis fat weight3.813.016.5-4.0-3.8-3.8-4.1-3.84.0-3.5-0.3
Delta time in closed arm before/after self-admin0.30.20.90.3-0.6-0.6-0.3-0.00.10.2-1.0
Delta time in open arm before/after self-admin0.30.30.50.50.50.50.70.7-0.60.10.1
Diff in mean of infusions in LGA sessions0.50.62.20.1-0.6-0.6-0.3-0.60.2-1.3-1.5
Delay discount exponential model param1.92.14.2-2.1-0.7-0.7-1.4-1.61.9-1.61.2
Extinction: sum of active levers before priming0.70.82.3-0.0-1.1-1.1-0.9-0.20.2-0.8-1.5
Active lever presses in extinction session 60.20.20.3-0.4-0.6-0.6-0.6-0.40.3-0.4-0.4
Bone: final force0.91.53.5-0.6-1.7-1.7-1.2-0.70.6-0.7-1.9
Bone: final moment1.01.64.3-0.6-1.7-1.7-1.1-0.80.5-0.7-2.1
Food consumed during 24 hour testing period1.11.62.7-0.8-1.7-1.7-1.1-1.30.8-0.8-1.4
Glucose0.10.20.6-0.60.20.2-0.4-0.40.4-0.80.6
Heart weight2.94.46.3-2.1-2.4-2.4-1.9-2.51.6-2.3-1.2
Delay discount hyperbolic model param1.92.13.8-2.0-0.7-0.7-1.3-1.81.8-1.61.1
Intermittent access intake day 1-15 change0.20.31.00.10.70.70.50.6-0.4-0.11.0
Intermittent access intake escalation0.30.51.10.30.90.90.70.8-0.6-0.11.0
Intermittent access intake escalation 20.40.41.00.20.90.90.70.4-0.50.11.0
Intermitt. access day 1 inactive lever presses0.10.20.9-0.3-0.4-0.4-0.3-0.9-0.0-0.2-0.6
Intermitt. access day 15 inactive lever presses0.30.61.21.10.70.71.00.1-1.1-0.0-0.5
Intermitt. access escalation Index0.30.40.80.50.80.80.70.2-0.30.90.7
Intermittent access day 1 total infusions0.50.84.31.0-0.6-0.6-0.10.2-0.6-0.2-2.1
Intermittent access day 15 total infusions0.60.82.01.40.60.60.91.2-1.20.4-0.5
Intermittent access terminal intake (last 3 days)0.40.61.71.30.40.40.60.8-1.00.3-0.6
Intermittent access total infusions0.80.93.61.5-0.2-0.20.30.5-1.10.2-1.9
Intermittent access day 1 locomotion0.40.51.60.90.10.10.40.4-1.00.4-1.3
Intermittent access day 15 total locomotion0.30.51.90.3-0.6-0.6-0.3-0.4-0.3-0.8-1.4
Intermittent access total locomotion0.70.83.50.5-0.6-0.6-0.1-1.0-0.4-0.8-1.9
Intermittent access standard deviation0.10.10.2-0.1-0.4-0.4-0.5-0.0-0.20.4-0.5
Left kidney weight8.539.350.0-5.8-7.1-7.1-6.8-6.96.4-6.2-2.8
Right kidney weight10.146.160.1-6.6-7.8-7.8-7.3-7.26.7-6.8-2.7
Cocaine induced anxiety1.82.53.5-1.3-1.9-1.9-1.6-1.71.4-1.7-1.1
Post-drug Anxiety0.70.71.5-0.8-0.7-0.7-0.6-1.21.0-1.20.0
Baseline Anxiety1.51.82.71.31.61.61.51.2-1.11.10.8
Tail length0.10.40.8-0.00.90.90.9-0.4-0.2-0.30.8
Length with tail0.73.05.7-1.8-1.4-1.4-1.3-2.31.9-2.4-0.4
Length without tail2.37.411.1-2.6-2.8-2.8-2.8-3.32.8-2.7-1.5
Times rat made contact with spout0.30.41.60.5-0.7-0.70.3-0.3-0.30.1-1.3
Lifetime Intake0.91.15.91.2-0.8-0.8-0.10.1-0.7-0.0-2.4
Liver weight, left1.22.03.4-1.4-1.5-1.5-1.6-1.31.8-1.30.5
Liver weight, right3.96.911.4-3.4-2.2-2.2-2.8-2.43.2-2.61.7
Locomotor activity1.32.02.6-1.6-1.5-1.5-1.5-1.61.6-1.1-0.3
Locomotor testing distance0.10.10.30.10.30.30.40.0-0.00.60.3
Locomotor testing rearing0.91.72.8-1.4-1.4-1.4-1.6-1.51.7-0.5-0.2
Locomotion in novel chamber1.92.45.00.71.91.91.41.6-0.91.02.2
Locomotion in novel chamber post-restriction0.40.61.10.60.90.90.61.1-0.60.80.8
Fecal boli incidents, locomotor time 10.60.92.31.30.60.61.1-0.0-1.10.4-1.5
Change in fecal boli incidents, locomotor task1.11.12.7-0.6-1.0-1.0-0.8-1.21.3-1.6-0.3
Time >=10cm from walls, locomotor time 10.60.60.8-0.6-0.8-0.8-0.8-0.90.5-0.9-0.9
Bouts of movement, locomotor time 11.31.42.1-0.8-1.5-1.5-1.2-1.31.3-1.0-0.8
Total resting periods, locomotor time 10.80.91.6-0.5-1.2-1.2-0.9-1.10.9-0.5-1.0
Rest time, locomotor task time 10.91.22.7-0.6-1.2-1.2-0.9-1.60.9-0.8-1.1
Distance moved, locomotor task time 10.20.31.3-0.9-0.2-0.2-0.50.20.5-0.01.1
Vertical activity count, locomotor time 10.10.10.2-0.30.40.40.3-0.40.0-0.40.5
Time >=10cm from walls, locomotor time 20.10.10.4-0.00.30.30.2-0.6-0.0-0.3-0.2
Bouts of movement, locomotor time 20.20.40.9-0.6-0.7-0.7-0.90.00.7-0.10.3
Total resting periods, locomotor time 20.10.20.5-0.3-0.7-0.7-0.70.20.4-0.0-0.2
Rest time, locomotor task time 20.20.20.90.7-0.1-0.10.3-0.2-0.1-0.2-1.0
Distance moved, locomotor task time 20.50.61.5-1.2-0.4-0.4-0.8-0.40.8-0.11.0
Vertical activity count, locomotor time 20.30.41.4-0.7-0.2-0.2-0.3-1.10.5-1.20.1
Light reinforcement 10.10.30.80.40.70.70.50.3-0.40.9-0.2
Light reinforcement 20.91.42.8-1.7-0.9-0.9-1.6-0.61.6-0.31.1
Bone: marrow area0.61.22.4-0.8-0.9-0.9-1.1-1.30.9-1.6-1.2
Bone: maximum diameter2.54.76.9-1.9-2.6-2.6-2.3-2.01.7-2.0-1.8
Bone: maximum force1.52.67.1-0.6-2.1-2.1-1.3-1.20.6-1.1-2.7
Bone: maximum moment1.62.97.8-0.6-2.2-2.2-1.4-1.40.7-1.1-2.8
Mean time between licks in bursts0.61.53.70.61.01.00.91.7-1.21.91.0
Mean num. licks in bursts1.32.13.7-1.3-1.9-1.9-1.5-1.41.3-1.0-0.5
Cd content in liver0.70.81.6-0.2-1.3-1.3-0.5-0.30.3-1.2-1.2
Co content in liver0.70.81.71.0-0.0-0.01.00.8-1.31.1-1.0
Cu content in liver6.57.713.02.53.13.13.03.6-3.12.30.5
Fe content in liver0.81.02.0-1.4-0.7-0.7-0.9-1.10.8-1.4-0.6
K content in liver0.80.81.70.81.31.30.90.8-0.60.30.7
Mg content in liver0.60.71.30.71.11.10.80.8-0.8-0.40.1
Mn content in liver0.10.10.50.0-0.1-0.1-0.2-0.20.4-0.70.3
Na content in liver1.11.22.40.71.61.61.21.0-1.00.40.6
Rb content in liver0.50.52.20.7-0.2-0.20.30.8-0.80.2-1.5
Se content in liver0.50.62.6-0.00.70.70.51.6-0.40.21.1
Sr content in liver3.32.85.31.31.61.61.72.3-1.71.71.3
Zn content in liver0.10.10.40.40.30.30.40.6-0.3-0.2-0.1
Bone: minimum diameter0.50.81.6-0.5-0.8-0.8-0.9-1.30.8-1.0-1.1
Time in familiar zone, hab. session 10.50.42.10.7-0.3-0.30.2-0.2-0.1-0.8-1.4
Time in novel zone, hab. session 10.70.72.0-1.4-0.4-0.4-0.8-0.80.70.21.2
Total zone transitions, hab. session 12.63.75.42.22.32.32.32.3-1.60.90.6
Total locomotion distance, hab. session 11.11.63.51.31.91.91.50.9-0.50.20.8
Locomotion velocity, hab. session 11.52.24.11.62.02.01.81.4-0.90.40.5
Time in familiar zone, hab. session 20.20.21.2-0.20.10.1-0.00.40.30.11.1
Time in novel zone, hab. session 20.20.21.00.3-0.1-0.10.1-0.4-0.40.1-1.0
Total zone transitions, hab. session 21.92.44.52.11.31.31.81.6-1.90.4-1.4
Total locomotion distance, hab. session 21.51.93.31.81.41.41.61.1-1.61.1-0.7
Locomotion velocity, hab. session 22.23.04.72.21.81.82.01.5-2.01.3-0.7
Novel to familiar place preference ratio1.51.62.7-1.5-1.6-1.6-1.1-0.80.9-1.70.0
Novelty place preference2.32.44.0-1.8-1.9-1.9-1.5-1.01.2-2.00.1
Time in novel zone, NPP test2.83.05.0-2.0-2.2-2.2-1.6-1.11.3-2.2-0.1
Total zone transitions, NPP test3.34.87.92.82.42.42.72.3-2.21.3-0.1
Total locomotion distance, NPP test1.62.24.02.01.61.61.81.2-1.41.0-0.4
Locomotion velocity, NPP test2.13.04.92.22.02.02.01.5-1.61.50.0
Intraocular pressure1.01.42.6-0.8-1.1-1.1-1.2-1.61.5-1.2-0.6
Delta distance traveled before/after self-admin1.01.13.0-0.3-0.5-0.5-0.2-1.70.5-1.7-1.3
Delta ambulatory time before/after self-admin0.81.02.6-0.1-0.6-0.6-0.1-1.40.2-1.6-1.6
Parametrial fat weight0.20.61.6-1.0-0.0-0.0-0.2-0.80.9-0.71.3
Pavlov. Cond. lever latency0.20.30.7-0.4-0.8-0.8-0.5-0.40.4-0.5-0.4
Pavlov. Cond. magazine entry latency0.50.71.41.20.60.60.80.9-1.00.8-0.4
Pavlov. Cond. change in total contacts1.51.63.11.81.21.21.41.0-1.60.9-1.0
Pavlov. Cond. index score0.20.30.70.80.50.50.50.2-0.60.5-0.4
Pavlov. Cond. latency score0.20.20.40.60.50.50.50.2-0.50.5-0.1
Pavlov. Cond. lever contacts0.91.11.81.01.41.41.10.7-0.91.10.4
Pavlov. Cond. magazine entry number0.60.81.8-1.4-0.6-0.6-0.9-0.81.0-0.70.5
Pavlov. Cond. intertrial magazine entries1.41.62.71.31.51.51.61.1-1.50.5-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.90.50.50.60.4-0.70.4-0.3
Pavlov. Cond. response bias0.50.71.31.20.80.80.80.8-0.90.7-0.3
Pavlov. Cond. lever latency0.60.91.8-0.4-1.3-1.3-0.9-0.80.8-0.9-0.6
Pavlov. Cond. magazine entry latency2.63.15.11.91.81.82.01.7-2.31.6-0.6
Pavlov. Cond. change in total contacts0.30.41.40.50.60.60.6-0.4-0.60.2-1.2
Pavlov. Cond. index score1.31.72.41.21.51.51.51.1-1.51.3-0.1
Pavlov. Cond. latency score1.72.23.21.51.81.81.71.2-1.71.4-0.1
Pavlov. Cond. lever contacts0.81.12.30.51.51.51.00.9-0.90.90.7
Pavlov. Cond. magazine entry number1.11.31.9-1.2-1.3-1.3-1.3-1.01.4-1.00.3
Pavlov. Cond. intertrial magazine entries1.11.72.9-0.6-1.6-1.6-1.2-1.71.0-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.1.31.72.61.21.61.61.51.1-1.51.40.0
Pavlov. Cond. response bias0.81.11.80.91.31.31.10.9-1.21.0-0.0
Time in closed arm before self-admin2.63.35.31.22.32.32.11.2-2.01.90.9
Time in closed arm after self-admin0.20.21.0-0.1-0.2-0.2-0.0-1.00.20.2-0.5
Time in open arm before self-admin0.10.10.4-0.2-0.2-0.2-0.3-0.10.6-0.10.6
Time in open arm after self-admin0.40.41.10.30.60.60.51.0-0.40.10.9
Bone: periosteal estimation0.91.92.4-1.1-1.5-1.5-1.5-1.41.1-1.5-1.6
Bone: periosteal perimeter2.84.86.2-2.1-2.4-2.4-2.5-2.42.2-2.1-1.1
Bone: post-yield work0.81.27.00.9-0.6-0.60.2-0.2-0.7-0.9-2.6
Progressive ratio test 1 active lever presses0.80.94.21.2-0.5-0.50.20.5-1.00.1-2.1
Progressive ratio test 1 breakpoint0.70.93.81.3-0.3-0.30.30.6-1.00.2-1.9
Progressive ratio test 1 inactive lever presses0.60.82.51.20.10.10.40.4-1.30.7-1.6
Progressive ratio test 2 active lever presses0.80.94.21.5-0.4-0.40.3-0.1-0.7-0.3-2.1
Progressive ratio test 2 breakpoint0.80.94.01.5-0.3-0.30.30.1-0.7-0.3-2.0
Progressive ratio test 2 inactive lever presses0.81.33.61.91.01.01.20.9-1.50.4-0.7
Incentive Sensitization - Responses0.10.20.90.90.30.30.5-0.1-0.1-0.1-0.3
Incentive Sensitization - Breakpoint0.10.10.60.80.10.10.3-0.20.0-0.3-0.5
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.0-0.00.00.1-0.1-0.30.1
Progressive ratio0.10.10.20.20.30.30.30.1-0.40.3-0.3
Food seeking constrained by brief footshock0.50.61.5-0.3-1.1-1.1-0.8-0.50.5-0.1-1.2
Seeking ratio, punishment vs. effort0.30.40.7-0.3-0.9-0.9-0.7-0.50.5-0.3-0.7
Retroperitoneal fat weight4.519.425.5-4.9-4.7-4.7-5.1-4.74.9-3.8-0.8
Reaction time number correct0.20.51.50.40.90.90.40.60.2-0.11.2
Reaction time mean minus median0.00.00.2-0.20.00.0-0.00.2-0.20.20.5
Reaction time mean minus median AUC0.30.71.2-1.1-0.8-0.8-1.0-0.60.8-0.70.7
Reaction time num false alarms0.10.20.8-0.40.30.30.1-0.10.10.40.9
Reaction time num false alarms AUC0.10.20.8-0.20.40.40.20.00.10.40.9
Reaction time trials correct on left0.20.51.50.40.90.90.40.60.2-0.11.2
Reaction time trials on left0.30.51.60.50.90.90.50.70.1-0.01.3
Reaction time mean0.10.10.5-0.30.30.30.00.2-0.10.00.7
Reaction time mean AUC0.00.10.3-0.20.20.2-0.00.1-0.0-0.10.6
Median of all reaction times0.10.10.5-0.20.40.40.00.4-0.20.00.7
Reaction time omissions0.40.50.90.90.80.80.60.9-0.70.70.3
Reaction time false alarm rate0.10.10.2-0.5-0.1-0.1-0.1-0.1-0.00.40.4
Reaction time premature initiation rate0.20.30.80.40.50.50.3-0.5-0.30.8-0.9
Reaction time premature initiations0.10.20.30.40.60.60.3-0.40.00.5-0.3
Std. dev. reaction times0.10.20.5-0.7-0.3-0.3-0.5-0.50.4-0.40.5
Reaction time trials completed0.30.51.60.50.90.90.50.70.1-0.01.3
Reaction time trials AUC0.20.31.20.20.70.70.20.40.4-0.21.1
Run reversals in cocaine runway, females0.10.10.30.00.50.50.3-0.30.1-0.30.5
Run reversals in cocaine runway, males0.80.81.8-0.0-1.4-1.4-0.7-0.00.6-0.8-1.3
Latency to leave start box in cocaine runway0.70.81.7-1.2-0.9-0.9-1.3-0.10.90.00.7
Latency to leave start box in cocaine runway, F0.20.20.8-0.2-0.2-0.2-0.30.9-0.20.70.3
Latency to leave start box in cocaine runway, M1.91.83.2-1.7-1.1-1.1-1.6-1.31.8-1.00.9
Std. dev. time between licks in bursts1.31.72.31.31.51.51.51.2-1.51.2-0.2
Total sessions with >9 infusions2.53.06.5-0.5-2.3-2.3-1.7-1.40.9-1.1-2.5
Short access day 1 total inactive lever presses1.11.47.61.1-0.2-0.20.7-0.2-1.30.5-2.8
Short access day 10 total inactive lever presses0.30.82.8-0.5-0.7-0.7-0.5-1.70.7-1.3-0.5
Short access day 1 total infusions0.40.52.40.2-0.7-0.7-0.4-0.80.1-0.2-1.6
Short access day 10 total infusions1.01.33.2-0.2-1.5-1.5-1.2-0.70.3-0.8-1.8
Short access total infusions1.51.97.30.2-1.6-1.6-1.1-0.90.2-0.7-2.7
Short access day 1 locomotion0.10.10.30.0-0.2-0.2-0.1-0.3-0.00.6-0.5
Short access day 10 total locomotion0.30.51.10.50.80.80.70.2-1.01.10.1
Short access total locomotion0.20.30.7-0.2-0.6-0.6-0.5-0.5-0.00.5-0.8
One hour access (0.3 mA shock)1.51.83.91.80.80.81.02.0-1.71.2-0.6
Compulsive drug intake0.70.82.31.50.80.81.20.1-0.80.1-0.9
One hour access (shock baseline)0.20.41.70.40.10.1-0.01.3-0.60.70.2
Social response proportion0.40.41.0-0.8-0.2-0.2-0.40.8-0.41.00.8
Social responses0.60.71.90.90.50.50.80.9-0.91.4-0.5
Social time2.83.85.61.92.02.01.92.2-2.22.40.3
Soleus weight0.30.92.41.60.60.61.2-0.4-0.60.8-1.0
Bone: stiffness0.71.22.7-0.8-1.4-1.4-1.0-1.00.5-0.7-1.6
Tibialis anterior weight1.96.312.42.31.81.82.43.4-2.93.50.2
Time to tail flick, vehicle, before self-admin0.10.10.30.20.10.10.20.0-0.3-0.5-0.5
Time to tail flick, vehicle, after self-admin0.50.71.40.51.01.01.20.4-0.71.00.3
Time to tail flick, test, before self-admin0.30.30.5-0.3-0.6-0.6-0.7-0.30.70.30.0
Time to tail flick, test, after self-admin0.30.30.50.40.70.70.60.2-0.40.70.6
Delta time to tail flick, vehicle, before/after SA0.20.21.10.20.30.30.40.2-0.51.0-0.2
Delta time to tail flick, test, before/after SA2.02.13.61.01.91.91.81.3-1.40.91.0
Tibia length0.71.93.9-0.5-1.6-1.6-1.2-0.80.9-1.8-2.0
Ambulatory time before self-admin0.71.02.21.00.90.90.81.3-0.91.50.3
Ambulatory time after self-admin1.51.73.01.51.41.41.70.9-1.70.7-0.7
Bone: tissue strength0.40.40.9-0.5-0.5-0.5-0.6-0.70.8-0.9-0.3
Total heroin consumption0.30.31.90.5-0.3-0.3-0.10.3-0.3-0.4-1.4
Bone: trabecular number0.10.10.4-0.4-0.1-0.1-0.2-0.30.60.00.5
Bone: trabecular spacing1.21.64.9-0.0-1.3-1.3-0.7-1.30.3-1.4-2.2
Bone: trabecular thickness0.40.52.2-0.50.60.60.00.50.10.71.5
Bone: trabecular tissue density1.82.63.90.61.91.91.72.0-1.81.31.2
Water consumed over 24 hours0.30.41.80.5-0.6-0.60.4-0.2-0.50.3-1.3
Number of responses in last shaping day0.91.02.31.20.60.60.71.1-1.51.2-0.8