Hub : Genes

Mgat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Mgat3 0.18 0.08 3.5e-07 0.16 0.17 0.19 0.18 2.3e-07 6.0e-08 1.6e-08 3.0e-08
2 Brain intron excision ratio chr7_111719574_111757284 0.03 0.02 4.9e-03 0.02 0.02 0.01 0.02 8.4e-03 8.2e-03 2.5e-02 7.1e-03
3 BLA gene expression Mgat3 0.1 0.07 5.6e-04 0.04 0.03 0.04 0.05 3.2e-03 8.6e-03 4.0e-03 1.3e-03
4 Adipose gene expression Mgat3 0.08 0.04 2.5e-06 0.04 0.02 0.03 0.03 2.8e-05 1.9e-03 8.2e-04 5.4e-04
5 IL gene expression Mgat3 0.34 0.14 1.6e-04 0.14 0.09 0.08 0.14 3.0e-04 3.5e-03 4.7e-03 3.7e-04
6 PL gene expression Mgat3 0.08 0.06 6.7e-06 0.02 0.04 0.04 0.04 1.0e-03 7.2e-05 1.6e-05 7.9e-05
7 NAcc intron excision ratio chr7_111719574_111757284 0.03 0.02 6.3e-03 0 0 0 0 1.5e-01 1.1e-01 1.4e-01 1.7e-01
8 NAcc mRNA stability Mgat3 0.04 0.03 7.7e-05 0.05 0.04 0.03 0.04 1.5e-06 2.6e-05 6.5e-05 9.7e-06
9 PL mRNA stability Mgat3 0.07 0.04 4.0e-06 0.05 0.05 0.06 0.05 2.6e-06 1.8e-06 4.7e-07 2.1e-06
10 Brain mRNA stability Mgat3 0.29 0.13 4.9e-09 0.12 0.11 0.1 0.11 7.9e-11 2.4e-10 1.7e-09 2.3e-10
11 IL mRNA stability Mgat3 0.27 0.13 1.3e-03 0.1 0.09 0.09 0.11 1.9e-03 4.6e-03 3.2e-03 1.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.30.8-0.5-0.80.6-0.9-0.50.1-0.50.40.2-0.00.4
Area under the delay curve2.72.86.1-2.5-2.11.7-1.1-0.8-1.4-1.71.92.00.9-1.5
BMI with tail0.41.43.81.11.0-1.21.11.91.01.1-1.3-1.70.30.4
BMI without tail0.30.52.1-0.3-0.70.5-1.0-0.1-0.4-0.3-0.0-0.9-0.91.4
Body weight1.66.510.13.22.7-3.02.93.13.02.7-2.4-2.01.0-0.4
Weight adjusted by age0.10.10.40.10.2-0.5-0.20.00.40.6-0.10.2-0.5-0.1
Bone surface0.20.30.9-0.3-0.40.1-0.20.10.7-0.30.61.00.9-0.9
Bone volume0.10.10.5-0.1-0.40.2-0.30.20.70.00.10.30.4-0.3
Breakpoint value in progressive ratio session0.10.10.4-0.3-0.30.6-0.4-0.4-0.2-0.60.40.1-0.20.3
Number of licking bursts0.91.02.2-1.2-0.71.5-1.0-1.1-0.7-0.91.21.30.3-0.6
Context. condit. distance diff. score6.07.211.73.22.7-2.92.62.62.63.4-3.1-3.0-1.01.1
Locomotion velocity, session 11.21.34.3-0.30.20.00.50.20.8-0.41.21.91.7-2.1
Locomotion distance, session 13.54.510.7-2.6-2.11.8-1.7-1.7-0.8-2.22.63.31.3-2.3
Locomotion velocity, session 20.30.41.00.40.5-1.00.70.80.70.2-0.30.10.7-0.5
Locomotion distance, session 24.15.711.1-2.8-2.32.2-1.8-1.9-1.5-3.03.03.31.6-2.1
Locomotion velocity, session 31.21.53.71.10.9-1.30.71.01.81.9-1.6-1.0-0.70.3
Locomotion distance, session 30.50.51.2-1.0-1.00.6-1.1-1.00.00.10.30.9-0.5-0.6
Stereotopy head waving bouts, day 30.70.81.91.01.4-0.51.21.40.70.4-0.3-0.31.2-0.5
Stereotopy head waving duration, day 32.73.26.02.32.4-1.92.22.41.61.5-1.3-1.41.10.0
Locomotion velocity, session 71.11.22.11.41.5-0.81.41.01.31.3-1.3-0.6-0.2-0.2
Locomotion distance, session 70.40.41.70.00.30.70.50.20.0-0.20.50.91.1-1.3
Stereotopy head waving bouts, day 74.04.58.12.52.4-2.82.02.21.92.5-2.5-2.1-0.40.8
Stereotopy head waving duration, day 73.74.57.82.31.9-2.71.51.81.32.5-2.8-2.8-1.41.7
Locomotion velocity, session 81.82.13.41.61.7-1.81.81.81.71.3-0.9-0.31.1-1.1
Locomotion distance, session 80.50.71.40.80.4-1.20.50.70.91.0-1.1-1.0-0.80.6
Degree of sensitization distance1.31.33.21.71.7-0.61.81.50.40.4-0.7-1.00.90.1
Degree of sensitization stereotypy3.03.27.71.91.6-2.81.41.71.42.2-2.3-1.9-0.90.8
Conditioned locomotion0.30.31.00.70.6-1.00.50.50.20.7-0.5-0.5-0.30.1
Cocaine response after cond. corrected0.10.10.60.20.40.10.60.40.7-0.10.30.10.4-0.1
Cocaine response after cond. not corrected0.10.10.30.20.10.20.30.20.6-0.10.0-0.2-0.10.4
Cocaine response before conditioning0.30.31.0-0.2-0.40.3-0.6-0.5-0.50.1-0.5-0.5-1.00.9
Saline control response0.60.83.20.50.2-0.4-0.4-0.6-0.50.6-0.9-0.9-1.81.4
Bone: connectivity density0.00.10.2-0.1-0.20.3-0.2-0.10.5-0.20.30.30.3-0.1
Bone: cortical apparent density0.10.10.3-0.4-0.50.2-0.6-0.5-0.10.4-0.00.3-0.40.1
Bone: cortical area0.91.33.21.01.1-1.01.31.81.50.6-0.6-0.31.4-0.8
Bone: cortical porosity1.01.12.31.41.1-1.11.21.10.50.6-1.1-1.5-0.21.0
Bone: cortical porosity1.71.93.31.81.6-1.61.81.61.00.8-1.3-1.50.30.6
Bone: cortical thickness0.20.31.2-0.3-0.00.50.20.60.3-0.30.30.41.1-0.8
Bone: cortical thickness0.81.02.7-1.0-0.70.9-0.10.2-0.0-0.91.01.21.6-1.5
Bone: cortical tissue density0.10.10.3-0.4-0.40.2-0.5-0.5-0.00.4-0.00.3-0.40.1
Condit. Reinf. active minus inactive responses0.20.20.7-0.4-0.10.5-0.20.0-0.3-0.20.40.90.6-0.7
Condit. Reinf. active-inactive response ratio0.20.20.60.40.5-0.10.30.70.20.7-0.5-0.10.0-0.2
Condit. Reinf. active responses0.81.01.7-1.1-1.31.1-1.3-1.3-1.2-0.90.70.9-0.40.1
Condit. Reinf. inactive responses2.02.45.8-1.6-2.11.2-2.1-2.4-1.7-1.30.90.7-1.10.8
Incentive salience index mean0.40.41.0-0.8-0.60.8-0.7-0.3-0.6-0.60.71.00.3-0.5
Condit. Reinf. lever presses0.30.50.9-1.0-0.80.6-0.9-0.6-0.7-0.70.70.7-0.00.0
Condit. Reinf. active minus inactive responses1.01.23.8-0.50.20.90.50.20.0-0.81.21.71.7-1.9
Condit. Reinf. active-inactive response ratio0.80.83.0-0.00.40.40.70.60.2-0.40.71.21.6-1.7
Condit. Reinf. active responses0.81.03.00.31.10.11.30.90.8-0.00.41.01.6-1.7
Condit. Reinf. inactive responses0.60.81.40.61.1-0.51.11.11.20.5-0.30.31.0-1.0
Condit. Reinf. lever presses0.50.61.4-0.8-0.61.2-0.8-0.5-0.9-1.00.90.90.2-0.6
Condit. Reinf. lever reinforcers received0.50.82.30.30.90.21.10.70.5-0.20.41.01.4-1.5
Conditioned reinforcement - actives0.80.82.3-1.0-0.50.8-0.1-0.4-0.1-0.71.01.31.2-1.5
Conditioned reinforcement - inactives2.12.44.8-1.7-1.52.2-1.1-1.1-1.1-1.82.01.71.1-0.9
Conditioned locomotion0.81.04.4-0.10.50.10.90.80.6-0.40.60.72.1-1.8
Patch foraging indifference point 0 sec0.40.61.3-0.4-1.00.6-1.1-0.9-1.1-0.90.70.2-0.20.5
Patch foraging indifference point AUC2.22.55.7-1.9-0.91.5-0.6-0.6-0.7-1.32.12.41.9-2.2
Delay disc. indifference point, 0s delay0.20.20.60.40.3-0.30.40.7-0.2-0.1-0.3-0.80.30.2
Delay disc. indifference point, 16s delay3.94.07.3-2.7-2.42.1-1.5-1.5-1.9-2.12.32.40.7-1.3
Delay disc. indifference point, 2s delay0.80.92.0-1.4-1.01.0-0.20.0-0.4-1.20.81.01.0-1.2
Delay disc. indifference point, 24s delay2.42.36.4-1.7-1.20.8-0.3-0.1-0.4-0.81.82.51.8-2.5
Delay disc. indifference point, 4s delay1.41.52.6-1.6-1.41.2-0.6-0.4-0.7-1.41.41.51.2-1.4
Delay disc. indifference point, 8s delay3.23.36.9-2.6-2.22.1-1.5-1.2-1.7-1.82.22.10.6-1.2
Indifference point function ln k3.04.26.82.61.8-2.51.51.61.52.3-2.6-2.6-1.41.6
Indifference point function log k3.04.26.82.61.8-2.51.51.61.52.3-2.6-2.6-1.41.6
Patch foraging total patch changes 0 sec0.71.12.2-0.8-1.40.9-1.4-1.1-1.5-1.21.00.4-0.20.5
Patch foraging total patch changes 12 sec0.30.40.8-0.4-0.10.40.1-0.1-0.7-0.70.80.80.9-0.8
Patch foraging total patch changes 18 sec1.62.04.0-1.2-0.91.7-0.5-0.5-1.2-1.72.01.71.8-1.4
Patch foraging total patch changes 24 sec1.01.22.3-1.1-1.01.5-0.8-0.8-1.3-1.21.31.20.5-0.6
Patch foraging total patch changes 6 sec1.82.74.7-1.5-1.31.8-1.3-1.1-1.5-2.12.21.91.6-1.4
Patch foraging time to switch 0 sec0.40.61.30.90.7-0.21.00.50.50.2-1.0-1.1-0.51.0
Patch foraging water rate 0 sec0.40.72.0-0.7-0.90.4-1.4-0.8-0.8-0.71.10.90.3-0.3
Patch foraging water rate 12 sec0.30.51.1-0.3-0.7-0.2-0.9-0.9-1.0-0.1-0.2-0.3-1.01.0
Patch foraging water rate 18 sec0.71.02.1-0.7-1.00.5-1.5-1.2-1.3-1.01.11.2-0.0-0.4
Patch foraging water rate 24 sec0.40.61.61.20.6-1.20.30.50.40.9-0.9-0.9-0.40.7
Patch foraging water rate 6 sec0.50.82.1-0.5-1.00.1-1.4-1.3-0.7-0.10.20.4-1.40.8
Seeking ratio, delayed vs. immediate footshock0.40.51.0-0.8-1.00.7-0.9-0.9-1.0-0.60.20.3-0.70.4
Distance traveled before self-admin0.60.72.2-1.1-0.81.5-0.6-0.4-0.9-1.20.70.30.30.1
Distance traveled after self-admin0.80.82.3-0.4-0.30.7-0.2-0.3-0.1-1.31.31.21.5-1.1
Extensor digitorum longus weight0.62.55.6-1.8-1.91.7-2.4-1.5-1.8-1.51.20.1-1.21.3
Bone: elastic displacement0.10.10.90.40.2-0.90.20.10.30.4-0.2-0.2-0.20.1
Bone: elastic work1.21.62.91.61.3-1.71.51.71.50.7-0.7-0.80.9-0.2
Bone: endosteal estimation1.02.14.11.81.5-2.01.81.71.80.9-0.9-0.61.2-0.7
Bone: endosteal perimeter1.94.08.22.52.2-2.92.42.32.31.7-1.8-1.30.6-0.1
Epididymis fat weight4.19.613.63.63.6-3.73.53.63.43.6-3.3-2.40.2-0.1
Delta time in closed arm before/after self-admin0.80.71.70.51.3-0.61.21.20.90.7-0.3-0.11.0-0.9
Delta time in open arm before/after self-admin0.40.41.0-0.5-1.00.6-0.8-0.8-0.8-0.80.40.2-0.30.6
Diff in mean of infusions in LGA sessions0.50.51.6-0.50.00.50.0-0.10.4-0.60.81.01.3-1.2
Delay discount exponential model param2.93.06.72.62.2-1.81.20.91.41.7-2.0-2.1-0.91.6
Extinction: sum of active levers before priming0.40.40.8-0.8-0.30.8-0.2-0.20.0-0.80.60.90.4-0.8
Active lever presses in extinction session 60.10.10.10.20.30.10.30.30.3-0.1-0.20.00.3-0.2
Bone: final force1.11.85.11.01.1-0.71.52.01.50.3-0.10.12.3-1.8
Bone: final moment1.21.95.81.01.1-0.61.52.11.50.3-0.00.22.4-1.8
Food consumed during 24 hour testing period0.81.02.40.91.4-0.61.21.50.80.4-0.3-0.21.4-1.0
Glucose0.20.31.30.40.2-0.00.1-0.5-0.2-0.1-0.4-0.8-0.71.2
Heart weight0.70.92.71.61.6-0.70.70.80.20.8-0.7-1.30.00.7
Delay discount hyperbolic model param2.62.86.22.52.1-1.71.00.81.31.7-1.9-2.0-1.01.5
Intermittent access intake day 1-15 change0.70.71.5-0.8-0.90.8-1.2-1.2-0.5-0.70.90.7-0.60.3
Intermittent access intake escalation0.70.71.4-0.8-0.90.8-1.2-1.2-0.4-0.70.80.6-0.70.4
Intermittent access intake escalation 20.40.41.0-0.5-0.60.7-0.9-1.0-0.5-0.70.70.5-0.60.3
Intermitt. access day 1 inactive lever presses0.20.20.6-0.4-0.70.50.10.1-0.3-0.70.70.30.7-0.2
Intermitt. access day 15 inactive lever presses0.60.71.9-0.3-0.10.70.00.10.4-0.61.01.31.4-1.4
Intermitt. access escalation Index0.50.41.3-0.8-0.70.9-0.7-0.5-1.1-0.50.60.3-0.20.1
Intermittent access day 1 total infusions0.60.73.3-0.00.30.21.00.90.7-0.30.40.41.8-1.3
Intermittent access day 15 total infusions0.70.81.9-0.9-0.71.0-0.3-0.3-0.0-1.01.41.21.1-0.9
Intermittent access terminal intake (last 3 days)0.40.41.0-0.7-0.40.8-0.1-0.30.1-0.71.00.90.8-0.6
Intermittent access total infusions0.70.72.8-0.40.10.90.50.40.4-0.81.00.91.7-1.2
Intermittent access day 1 locomotion0.30.31.9-0.10.20.50.50.5-0.0-0.50.60.11.4-0.6
Intermittent access day 15 total locomotion0.40.41.40.40.80.20.90.80.80.10.10.21.2-0.7
Intermittent access total locomotion0.80.93.40.71.20.41.20.90.8-0.10.40.31.8-1.1
Intermittent access standard deviation0.10.10.30.1-0.00.00.20.40.6-0.40.30.10.5-0.1
Left kidney weight9.326.140.75.86.2-5.46.36.46.25.3-4.5-3.02.5-1.9
Right kidney weight9.125.740.35.96.2-5.56.36.36.04.9-4.0-2.73.1-2.3
Cocaine induced anxiety1.41.62.51.51.1-1.01.41.51.61.3-1.4-1.50.10.4
Post-drug Anxiety0.80.91.71.30.7-1.21.01.01.01.1-0.9-0.80.10.1
Baseline Anxiety0.90.91.9-1.0-0.80.9-1.1-1.1-1.3-0.71.21.4-0.1-0.3
Tail length0.10.20.70.50.00.0-0.3-0.50.10.20.0-0.4-0.70.8
Length with tail1.14.07.32.72.2-2.52.31.82.72.3-1.7-1.00.6-0.5
Length without tail2.96.311.12.82.9-3.13.32.73.02.5-1.9-0.51.6-1.7
Times rat made contact with spout0.50.61.8-0.7-0.30.6-0.40.10.5-0.31.00.91.3-1.2
Lifetime Intake0.80.94.2-0.00.60.61.00.90.8-0.60.70.62.1-1.4
Liver weight, left1.32.13.51.51.4-1.71.41.51.21.9-1.8-1.5-0.40.8
Liver weight, right5.18.513.33.23.0-3.62.92.42.73.6-3.6-3.1-1.41.5
Locomotor activity1.22.04.51.72.1-1.51.61.71.11.4-1.1-1.20.40.2
Locomotor testing distance0.00.10.2-0.10.20.2-0.30.1-0.40.30.1-0.1-0.20.4
Locomotor testing rearing1.11.63.11.41.7-1.31.51.61.01.4-1.3-1.20.30.4
Locomotion in novel chamber2.63.26.8-1.7-2.11.3-2.6-2.4-1.8-0.70.70.3-2.61.8
Locomotion in novel chamber post-restriction0.40.40.8-0.9-0.50.9-0.8-0.8-0.6-0.60.40.3-0.60.4
Fecal boli incidents, locomotor time 11.51.63.6-1.0-0.41.6-0.6-0.6-0.8-1.51.91.71.5-1.1
Change in fecal boli incidents, locomotor task0.90.82.00.81.0-1.00.80.81.21.4-0.80.10.2-1.0
Time >=10cm from walls, locomotor time 10.50.51.50.60.5-0.61.10.70.90.2-0.3-0.11.2-0.5
Bouts of movement, locomotor time 11.01.12.01.11.4-0.91.21.41.21.1-0.7-0.30.7-0.8
Total resting periods, locomotor time 10.50.51.30.71.0-0.40.91.10.70.6-0.2-0.10.9-0.8
Rest time, locomotor task time 10.40.41.50.60.90.40.70.80.30.00.30.01.2-0.5
Distance moved, locomotor task time 10.80.92.10.60.2-1.50.50.40.51.0-1.5-1.2-1.10.9
Vertical activity count, locomotor time 10.10.10.40.50.1-0.6-0.0-0.20.00.3-0.3-0.1-0.50.0
Time >=10cm from walls, locomotor time 20.10.10.30.3-0.10.3-0.1-0.20.2-0.20.40.30.5-0.2
Bouts of movement, locomotor time 20.60.61.20.81.0-0.40.80.90.70.6-1.1-1.1-0.10.6
Total resting periods, locomotor time 20.30.30.60.50.8-0.10.70.80.50.3-0.7-0.60.30.1
Rest time, locomotor task time 20.50.51.4-0.6-0.30.8-0.2-0.2-0.1-0.61.01.21.0-0.9
Distance moved, locomotor task time 21.01.12.41.20.8-1.30.70.60.61.1-1.4-1.5-0.91.1
Vertical activity count, locomotor time 20.50.51.71.31.0-0.70.60.50.90.6-0.6-0.60.00.1
Light reinforcement 10.00.10.4-0.3-0.20.2-0.1-0.2-0.6-0.30.20.10.20.1
Light reinforcement 21.41.94.51.21.0-1.51.01.10.81.6-2.0-2.1-1.11.4
Bone: marrow area1.02.24.41.81.5-2.11.91.71.91.0-0.9-0.61.2-0.7
Bone: maximum diameter2.64.99.12.42.5-2.62.83.02.61.7-1.5-1.11.9-1.0
Bone: maximum force1.73.08.81.31.5-1.01.92.52.10.4-0.10.23.0-2.1
Bone: maximum moment1.83.19.61.31.6-1.02.02.62.10.4-0.10.23.1-2.1
Mean time between licks in bursts1.01.43.4-1.2-1.21.1-1.4-1.5-1.9-1.10.80.3-1.00.8
Mean num. licks in bursts0.81.02.01.00.8-1.41.01.41.31.1-0.8-0.80.6-0.3
Cd content in liver0.20.20.60.2-0.2-0.3-0.30.2-0.20.5-0.5-0.8-0.60.5
Co content in liver0.20.20.7-0.4-0.6-0.2-0.8-0.1-0.8-0.40.40.10.3-0.2
Cu content in liver3.13.88.3-2.4-2.91.7-2.8-2.0-2.0-1.91.51.3-0.80.5
Fe content in liver0.60.72.01.40.1-1.30.50.30.80.7-1.0-1.0-0.40.7
K content in liver0.30.30.7-0.6-0.50.6-0.5-0.7-0.3-0.80.60.6-0.20.0
Mg content in liver0.20.20.7-0.4-0.60.4-0.3-0.6-0.1-0.80.40.5-0.10.2
Mn content in liver0.20.20.50.20.6-0.60.20.40.40.6-0.7-0.2-0.4-0.1
Na content in liver1.21.22.8-1.1-1.11.0-1.5-1.7-1.4-1.20.90.6-0.60.6
Rb content in liver0.20.20.5-0.5-0.5-0.0-0.5-0.0-0.2-0.50.50.70.6-0.7
Se content in liver0.80.92.7-0.7-1.6-0.1-1.5-0.9-0.20.2-0.3-0.3-1.61.0
Sr content in liver2.72.55.7-2.2-1.91.9-2.4-1.4-1.9-1.11.10.6-1.10.6
Zn content in liver0.80.82.1-1.1-1.40.6-1.2-1.2-0.6-0.90.50.6-0.80.4
Bone: minimum diameter0.71.42.61.41.3-1.01.61.61.50.6-0.7-0.21.2-0.7
Time in familiar zone, hab. session 10.80.73.1-0.30.20.2-0.00.4-0.2-0.30.81.21.5-1.7
Time in novel zone, hab. session 11.21.23.51.00.5-1.10.70.00.80.7-1.1-1.7-1.21.9
Total zone transitions, hab. session 12.02.85.3-2.2-2.31.3-2.3-2.1-0.9-1.11.42.1-0.6-0.6
Total locomotion distance, hab. session 10.50.81.9-1.1-1.00.4-1.2-1.4-0.3-0.20.51.2-0.8-0.0
Locomotion velocity, hab. session 10.91.32.4-1.5-1.40.9-1.5-1.5-0.5-0.60.91.6-0.5-0.3
Time in familiar zone, hab. session 20.30.31.2-0.2-0.50.1-0.5-0.2-0.20.5-0.4-0.5-1.10.7
Time in novel zone, hab. session 20.30.31.00.20.4-0.20.40.00.1-0.60.50.61.0-0.7
Total zone transitions, hab. session 22.33.06.8-1.9-1.61.4-1.3-1.0-0.8-1.82.32.61.5-1.9
Total locomotion distance, hab. session 21.41.83.5-1.5-1.11.2-1.1-1.3-1.1-1.71.81.90.7-0.9
Locomotion velocity, hab. session 22.02.74.9-1.9-1.51.6-1.4-1.6-1.4-2.12.12.20.8-1.0
Novel to familiar place preference ratio1.41.45.01.41.2-2.20.91.01.21.4-1.0-1.00.00.1
Novelty place preference2.12.16.51.61.5-2.51.21.31.51.8-1.3-1.2-0.10.1
Time in novel zone, NPP test2.42.47.11.71.6-2.71.31.51.62.0-1.4-1.30.10.0
Total zone transitions, NPP test3.04.38.0-2.7-2.51.7-2.4-2.2-1.3-1.82.32.80.1-1.3
Total locomotion distance, NPP test1.31.84.4-1.7-1.31.0-1.3-1.5-0.9-1.31.62.10.3-1.0
Locomotion velocity, NPP test1.62.24.3-1.9-1.61.2-1.6-1.8-1.2-1.51.62.1-0.0-0.7
Intraocular pressure1.11.53.61.61.9-1.01.51.31.41.2-1.0-0.50.7-0.7
Delta distance traveled before/after self-admin0.91.01.91.10.9-1.20.90.71.40.50.00.61.4-1.4
Delta ambulatory time before/after self-admin1.01.13.20.70.8-1.10.80.61.20.20.51.01.8-1.7
Parametrial fat weight0.10.20.60.80.7-0.40.30.50.10.7-0.6-0.40.10.1
Pavlov. Cond. lever latency0.20.20.50.60.6-0.20.70.60.50.5-0.2-0.30.5-0.4
Pavlov. Cond. magazine entry latency0.91.22.1-1.5-1.01.1-1.0-1.0-1.0-1.41.31.10.5-0.6
Pavlov. Cond. change in total contacts1.92.03.4-1.6-1.11.5-1.1-1.1-1.4-1.81.61.81.1-1.2
Pavlov. Cond. index score0.20.30.6-0.7-0.30.4-0.3-0.4-0.3-0.80.70.70.5-0.4
Pavlov. Cond. latency score0.10.20.4-0.6-0.30.3-0.3-0.4-0.3-0.60.50.50.2-0.1
Pavlov. Cond. lever contacts0.40.50.8-0.9-0.60.6-0.7-0.9-0.9-0.90.60.6-0.30.3
Pavlov. Cond. magazine entry number0.50.61.21.10.6-0.80.70.70.50.9-1.0-1.0-0.50.7
Pavlov. Cond. intertrial magazine entries1.21.53.5-1.1-1.31.2-1.2-1.2-0.9-1.31.41.90.7-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.7-0.8-0.40.5-0.4-0.5-0.4-0.80.70.70.4-0.4
Pavlov. Cond. response bias0.50.61.2-1.0-0.60.7-0.6-0.6-0.7-1.10.90.90.4-0.4
Pavlov. Cond. lever latency0.70.92.90.71.1-0.81.31.01.71.0-0.6-0.20.8-0.6
Pavlov. Cond. magazine entry latency2.83.25.4-1.9-2.02.0-2.0-1.7-1.8-2.32.01.80.3-0.8
Pavlov. Cond. change in total contacts0.50.71.6-0.0-0.20.5-0.2-0.2-0.7-1.31.01.11.1-1.2
Pavlov. Cond. index score1.51.93.1-1.3-1.51.6-1.6-1.4-1.7-1.81.41.2-0.1-0.4
Pavlov. Cond. latency score1.92.33.8-1.5-1.71.8-1.7-1.6-1.8-2.01.61.4-0.0-0.5
Pavlov. Cond. lever contacts0.50.72.1-0.6-0.90.7-1.2-0.8-1.5-0.90.40.1-0.80.7
Pavlov. Cond. magazine entry number1.01.22.01.11.2-1.31.41.01.11.4-1.2-1.2-0.20.7
Pavlov. Cond. intertrial magazine entries0.70.91.90.81.3-0.41.41.31.00.7-0.3-0.11.3-0.5
Pavlov. Cond. lever-magazine prob. diff.1.31.72.8-1.2-1.51.5-1.7-1.4-1.6-1.71.31.1-0.2-0.2
Pavlov. Cond. response bias0.70.92.2-0.8-1.11.0-1.2-0.8-1.5-1.30.90.7-0.1-0.1
Time in closed arm before self-admin3.43.97.8-2.0-2.52.1-2.1-2.3-2.8-2.51.70.9-0.60.8
Time in closed arm after self-admin0.30.30.70.30.6-0.40.80.70.00.2-0.2-0.30.8-0.3
Time in open arm before self-admin0.30.31.00.60.7-0.30.20.40.71.0-0.4-0.4-0.50.3
Time in open arm after self-admin0.50.62.2-0.1-0.60.5-0.9-0.8-0.40.0-0.3-0.5-1.51.3
Bone: periosteal estimation1.32.74.91.81.7-2.02.12.22.11.0-1.0-0.71.6-0.9
Bone: periosteal perimeter3.15.18.42.72.6-2.82.82.92.71.8-1.9-1.41.2-0.4
Bone: post-yield work1.21.67.0-0.7-0.00.60.30.60.7-1.01.41.52.6-1.8
Progressive ratio test 1 active lever presses1.11.14.0-0.8-0.31.20.30.40.1-0.91.21.12.0-1.5
Progressive ratio test 1 breakpoint0.80.82.9-0.8-0.31.20.10.3-0.1-0.71.11.01.7-1.2
Progressive ratio test 1 inactive lever presses0.50.62.5-0.5-0.41.6-0.2-0.4-0.4-1.30.90.20.9-0.2
Progressive ratio test 2 active lever presses0.80.92.6-0.6-0.11.10.20.00.4-0.60.91.41.6-1.6
Progressive ratio test 2 breakpoint0.80.92.9-0.40.11.00.40.20.4-0.60.91.21.7-1.6
Progressive ratio test 2 inactive lever presses1.41.74.2-1.4-1.12.1-0.7-0.9-0.4-1.51.61.61.0-0.9
Incentive Sensitization - Responses0.10.10.20.00.00.4-0.1-0.40.1-0.0-0.10.4-0.2-0.2
Incentive Sensitization - Breakpoint0.10.10.10.20.20.30.1-0.10.30.2-0.20.3-0.0-0.3
Sum of active levers in priming session hrs 5-60.20.20.4-0.5-0.50.6-0.5-0.5-0.4-0.60.40.1-0.20.5
Progressive ratio0.40.41.0-0.5-0.70.9-0.5-0.5-0.5-0.91.00.70.30.0
Food seeking constrained by brief footshock0.40.51.30.20.5-0.50.91.20.90.4-0.20.11.1-0.8
Seeking ratio, punishment vs. effort0.30.30.80.20.6-0.50.80.90.60.5-0.6-0.20.6-0.6
Retroperitoneal fat weight5.518.027.15.15.2-4.84.94.74.44.7-4.5-3.60.80.1
Reaction time number correct0.20.31.5-0.2-0.5-0.0-0.7-0.7-0.10.4-0.40.1-1.20.5
Reaction time mean minus median0.10.10.40.30.1-0.0-0.1-0.3-0.2-0.1-0.0-0.4-0.50.7
Reaction time mean minus median AUC0.60.71.51.21.0-0.80.70.40.40.8-1.0-1.2-0.70.9
Reaction time num false alarms0.20.20.80.30.0-0.3-0.3-0.2-0.80.1-0.1-0.4-0.90.6
Reaction time num false alarms AUC0.10.20.80.1-0.2-0.1-0.4-0.4-0.70.00.0-0.1-0.90.6
Reaction time trials correct on left0.20.31.5-0.2-0.5-0.0-0.7-0.7-0.10.4-0.40.1-1.20.5
Reaction time trials on left0.20.31.6-0.3-0.60.1-0.7-0.7-0.20.3-0.40.1-1.30.5
Reaction time mean0.20.31.20.2-0.3-0.1-0.1-0.40.0-0.1-0.3-0.8-0.81.1
Reaction time mean AUC0.10.20.80.2-0.2-0.1-0.1-0.20.20.0-0.3-0.6-0.60.9
Median of all reaction times0.20.21.0-0.1-0.60.0-0.3-0.40.0-0.3-0.2-0.6-0.71.0
Reaction time omissions0.30.51.0-0.8-1.00.8-0.6-0.8-0.8-0.80.50.4-0.50.2
Reaction time false alarm rate0.10.10.40.30.0-0.2-0.1-0.1-0.6-0.00.0-0.4-0.40.5
Reaction time premature initiation rate0.10.20.6-0.0-0.20.20.20.0-0.5-0.60.60.40.8-0.3
Reaction time premature initiations0.00.00.10.0-0.20.00.1-0.1-0.3-0.20.30.40.2-0.1
Std. dev. reaction times0.20.30.70.90.5-0.60.50.20.40.5-0.5-0.9-0.40.8
Reaction time trials completed0.20.31.6-0.3-0.60.1-0.7-0.7-0.20.3-0.40.1-1.30.5
Reaction time trials AUC0.10.21.20.0-0.3-0.1-0.4-0.40.00.5-0.5-0.0-1.10.5
Run reversals in cocaine runway, females0.20.20.60.2-0.2-0.4-0.3-0.6-0.30.4-0.6-0.3-0.80.7
Run reversals in cocaine runway, males0.70.72.2-0.30.4-0.80.81.00.90.60.30.81.2-1.5
Latency to leave start box in cocaine runway1.82.04.01.51.3-2.01.21.00.91.4-2.0-1.8-0.90.9
Latency to leave start box in cocaine runway, F0.20.20.60.10.0-0.80.1-0.0-0.20.2-0.7-0.6-0.80.5
Latency to leave start box in cocaine runway, M3.63.56.02.21.9-2.11.81.51.92.0-2.4-2.2-0.61.0
Std. dev. time between licks in bursts1.01.21.9-1.0-1.31.0-1.2-1.2-1.2-1.41.31.20.1-0.2
Total sessions with >9 infusions1.41.54.60.81.3-0.21.71.51.60.4-0.10.22.1-1.3
Short access day 1 total inactive lever presses1.51.75.9-0.8-0.31.00.00.1-0.1-1.41.81.72.4-1.8
Short access day 10 total inactive lever presses0.00.00.10.40.1-0.30.10.10.10.20.20.20.3-0.0
Short access day 1 total infusions0.50.51.60.61.00.30.70.71.0-0.10.10.01.3-0.7
Short access day 10 total infusions1.01.23.50.71.1-0.31.61.61.10.1-0.0-0.21.9-1.0
Short access total infusions1.41.65.30.91.6-0.21.81.71.30.1-0.1-0.22.3-1.2
Short access day 1 locomotion0.20.30.9-0.10.31.0-0.1-0.2-0.2-0.80.70.20.8-0.2
Short access day 10 total locomotion0.60.72.1-0.1-0.01.4-0.6-0.8-1.1-1.20.7-0.6-0.00.9
Short access total locomotion0.50.52.50.51.00.50.90.80.0-0.40.3-0.41.6-0.3
One hour access (0.3 mA shock)1.41.63.3-1.8-1.41.7-0.8-0.9-1.1-1.51.51.30.6-0.7
Compulsive drug intake2.22.23.7-1.9-1.61.3-1.6-1.9-1.5-1.11.41.9-0.1-1.1
One hour access (shock baseline)0.10.10.30.10.10.30.40.50.1-0.20.0-0.40.30.3
Social response proportion0.30.41.50.0-0.4-0.2-0.2-0.2-0.9-0.6-0.1-0.9-0.61.2
Social responses0.50.62.0-0.8-0.40.6-0.4-0.6-1.4-1.01.10.80.6-0.6
Social time2.63.46.2-2.2-2.12.1-1.7-2.0-2.5-2.41.81.4-0.00.0
Soleus weight0.61.74.1-1.2-0.71.7-0.8-0.9-0.9-1.31.82.00.9-1.5
Bone: stiffness1.01.64.71.21.2-0.71.51.91.50.3-0.3-0.22.2-1.2
Tibialis anterior weight1.75.89.5-3.0-2.83.1-2.8-2.2-2.7-2.82.61.7-0.10.0
Time to tail flick, vehicle, before self-admin0.20.20.70.10.4-0.00.20.00.4-0.00.40.80.6-0.9
Time to tail flick, vehicle, after self-admin0.30.30.7-0.5-0.8-0.1-0.9-0.7-0.7-0.10.3-0.0-0.70.5
Time to tail flick, test, before self-admin0.10.10.3-0.6-0.20.10.10.2-0.2-0.0-0.00.30.2-0.3
Time to tail flick, test, after self-admin1.11.22.0-1.3-1.21.2-1.3-1.4-1.3-0.90.80.7-0.80.4
Delta time to tail flick, vehicle, before/after SA0.40.41.0-0.7-1.00.3-0.7-0.5-0.9-0.50.3-0.4-0.50.8
Delta time to tail flick, test, before/after SA1.81.73.8-1.1-1.51.2-1.8-1.9-1.2-1.00.90.6-1.40.9
Tibia length0.82.14.81.11.4-1.11.92.21.81.0-0.30.22.0-1.6
Ambulatory time before self-admin1.01.02.8-1.3-1.11.7-1.0-0.8-1.1-1.10.90.7-0.0-0.1
Ambulatory time after self-admin1.31.43.1-1.1-0.91.0-0.9-0.9-0.4-1.51.81.71.2-1.1
Bone: tissue strength0.40.41.30.80.5-0.70.60.71.10.6-0.5-0.20.3-0.2
Total heroin consumption0.30.41.8-0.5-0.00.10.10.1-0.0-0.30.50.91.0-1.3
Bone: trabecular number0.20.41.10.40.3-0.50.00.21.10.8-0.7-0.6-0.60.6
Bone: trabecular spacing1.01.44.90.50.9-0.31.31.30.5-0.20.50.92.2-2.0
Bone: trabecular thickness0.50.62.50.2-0.20.0-0.6-0.3-0.00.4-0.8-1.0-1.41.6
Bone: trabecular tissue density1.21.73.6-1.1-1.80.9-1.9-1.6-1.9-1.20.80.1-0.70.9
Water consumed over 24 hours0.40.52.3-0.5-0.00.1-0.30.50.2-0.20.90.81.5-1.2
Number of responses in last shaping day1.11.13.3-1.0-0.71.6-0.1-0.4-0.5-1.81.11.11.1-0.9