Hub : Genes

Mfsd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Mfsd1 0.23 0.1 0.0e+00 0.1 0.13 0.13 0.13 1.5e-11 1.7e-14 2.3e-14 4.0e-14
2 Adipose mRNA stability Mfsd1 0.1 0.06 1.4e-06 0.01 0.04 0.04 0.03 2.6e-02 4.4e-05 2.1e-05 2.3e-04
3 NAcc gene expression Mfsd1 0.05 0.03 2.3e-06 0.06 0.05 0.04 0.04 3.8e-07 1.8e-06 5.4e-06 7.6e-06
4 Brain mRNA stability Mfsd1 0.05 0.03 4.4e-05 0.04 0.03 0.02 0.03 7.0e-05 6.1e-04 8.5e-03 9.2e-04
5 BLA mRNA stability Mfsd1 0.09 0.05 2.9e-03 0.07 0.03 0.05 0.05 2.0e-04 6.1e-03 1.6e-03 7.6e-04
6 LHb mRNA stability Mfsd1 0.23 0.12 9.3e-04 0.13 0.1 0.11 0.09 5.2e-04 2.2e-03 1.2e-03 4.8e-03
7 IL mRNA stability Mfsd1 0.18 0.11 7.5e-03 -0.01 0.04 0.02 0.02 5.3e-01 4.7e-02 1.2e-01 1.0e-01
8 Brain gene expression Mfsd1 0.16 0.08 6.7e-14 0.14 0.16 0.16 0.16 9.1e-13 1.3e-14 2.0e-14 2.4e-14
9 BLA gene expression Mfsd1 0.07 0.04 7.9e-03 0.01 0.01 0.05 0.01 5.3e-02 5.5e-02 1.8e-03 1.4e-01
10 Liver mRNA stability Mfsd1 0.05 0.03 2.3e-04 0.03 0.04 0.03 0.03 3.3e-04 8.9e-05 3.7e-04 4.8e-04
11 PL gene expression Mfsd1 0.11 0.05 4.3e-11 0.1 0.09 0.09 0.09 9.4e-11 6.0e-10 3.0e-10 2.1e-10
12 IL gene expression Mfsd1 0.39 0.16 1.4e-03 0.02 0.02 0.05 0.05 1.1e-01 1.3e-01 2.5e-02 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density2.74.627.65.3-3.41.31.51.31.21.2-1.31.7-0.31.40.5
Area under the delay curve0.70.75.30.60.4-0.30.20.80.90.50.62.30.4-0.50.2
BMI with tail1.23.99.00.70.2-2.1-1.8-1.5-1.42.73.0-1.32.7-2.7-1.7
BMI without tail0.20.51.41.20.80.00.20.60.90.80.90.20.4-0.6-0.5
Body weight0.83.36.60.5-0.2-2.1-1.8-1.7-1.42.42.6-1.52.4-2.3-1.0
Weight adjusted by age0.50.51.61.3-0.1-0.4-0.1-0.4-0.41.00.6-1.00.6-0.7-0.8
Bone surface1.72.914.33.8-3.7-0.6-0.5-0.4-0.62.20.10.41.10.10.4
Bone volume2.13.620.64.5-3.90.30.50.40.31.7-0.71.40.41.00.9
Breakpoint value in progressive ratio session0.20.20.8-0.9-0.1-0.40.2-0.10.0-0.3-0.30.0-0.10.10.8
Number of licking bursts1.01.25.92.1-2.4-0.1-0.7-0.3-0.51.40.20.90.80.1-0.3
Context. condit. distance diff. score2.12.54.92.00.21.92.02.12.2-0.8-1.51.7-1.51.20.3
Locomotion velocity, session 10.20.20.5-0.30.30.50.50.40.4-0.5-0.30.7-0.40.4-0.0
Locomotion distance, session 10.40.51.7-1.3-0.3-0.9-0.9-0.9-0.90.10.2-0.30.4-0.10.0
Locomotion velocity, session 20.40.41.50.1-1.00.1-0.1-0.1-0.0-0.2-0.70.8-0.31.21.2
Locomotion distance, session 20.91.32.9-1.7-0.4-1.6-1.5-1.6-1.60.40.6-0.41.0-0.40.9
Locomotion velocity, session 31.11.34.41.1-2.1-1.0-1.0-1.2-1.21.60.60.61.3-0.30.6
Locomotion distance, session 30.90.95.12.3-1.70.30.50.30.20.8-0.31.30.30.30.7
Stereotopy head waving bouts, day 30.40.41.71.3-1.00.20.20.20.20.4-0.51.1-0.10.60.6
Stereotopy head waving duration, day 30.40.52.01.4-1.10.10.10.10.20.4-0.51.2-0.00.70.8
Locomotion velocity, session 70.30.32.0-1.40.7-0.4-0.1-0.1-0.0-0.7-0.30.0-0.3-0.00.5
Locomotion distance, session 71.11.42.7-0.81.51.31.41.21.2-1.7-1.1-0.1-1.50.7-0.2
Stereotopy head waving bouts, day 70.40.41.1-0.2-1.0-0.8-0.8-0.7-0.60.5-0.00.70.40.30.9
Stereotopy head waving duration, day 71.51.83.9-0.2-1.6-1.8-2.0-1.7-1.61.61.10.31.6-0.60.6
Locomotion velocity, session 80.30.40.7-0.2-0.4-0.7-0.9-0.7-0.60.80.8-0.20.8-0.6-0.0
Locomotion distance, session 80.10.10.4-0.6-0.1-0.3-0.1-0.3-0.3-0.2-0.20.20.00.20.5
Degree of sensitization distance2.42.49.1-2.93.00.70.80.70.9-2.1-0.5-1.3-1.40.1-0.8
Degree of sensitization stereotypy0.40.40.9-0.9-0.5-0.9-1.0-0.8-0.70.30.20.30.50.10.6
Conditioned locomotion0.30.40.70.4-0.8-0.6-0.8-0.7-0.60.80.60.00.8-0.40.2
Cocaine response after cond. corrected0.70.84.7-0.82.20.60.60.81.0-0.60.6-0.3-0.3-0.8-0.2
Cocaine response after cond. not corrected0.50.51.6-0.91.3-0.2-0.3-0.2-0.10.11.1-0.90.5-1.2-0.5
Cocaine response before conditioning1.01.24.20.8-2.0-0.8-1.0-1.3-1.41.30.5-0.91.0-0.4-0.7
Saline control response2.73.67.51.6-2.7-1.7-1.8-2.1-2.22.61.5-1.12.2-1.4-0.8
Bone: connectivity density1.42.216.24.0-2.40.60.80.70.71.4-0.40.60.20.4-0.1
Bone: cortical apparent density4.05.39.50.42.43.13.13.02.8-2.6-1.90.9-2.71.6-0.2
Bone: cortical area1.52.27.82.6-2.8-1.2-1.0-1.1-0.82.20.7-0.31.4-0.50.2
Bone: cortical porosity1.71.93.6-1.8-0.4-1.8-1.9-1.9-1.80.81.2-0.71.4-1.00.2
Bone: cortical porosity1.92.04.3-1.1-1.1-1.8-2.1-2.1-1.91.21.2-0.51.6-0.70.6
Bone: cortical thickness0.40.74.82.2-1.40.10.30.10.40.7-0.40.40.00.40.5
Bone: cortical thickness1.51.79.23.0-2.5-0.3-0.3-0.4-0.31.90.40.80.90.10.1
Bone: cortical tissue density4.15.49.80.42.53.13.13.02.9-2.7-1.90.9-2.71.6-0.2
Condit. Reinf. active minus inactive responses2.52.84.4-1.4-0.2-2.1-2.1-2.0-1.91.41.9-1.51.8-2.0-0.5
Condit. Reinf. active-inactive response ratio2.02.14.2-1.5-0.3-2.1-2.0-1.9-1.81.11.4-0.91.5-1.40.1
Condit. Reinf. active responses3.94.87.7-1.6-0.2-2.8-2.7-2.5-2.41.92.5-1.82.4-2.7-0.8
Condit. Reinf. inactive responses1.11.33.7-0.80.8-0.9-0.8-0.7-0.80.81.5-1.41.0-1.9-1.4
Incentive salience index mean1.72.03.3-1.80.2-1.7-1.7-1.7-1.60.71.4-1.71.3-1.6-0.6
Condit. Reinf. lever presses0.70.94.2-2.10.7-0.8-0.7-0.8-0.9-0.40.3-1.70.1-0.6-0.7
Condit. Reinf. active minus inactive responses1.01.22.40.6-0.9-1.2-1.0-1.0-1.01.51.1-0.81.3-1.4-1.1
Condit. Reinf. active-inactive response ratio0.50.62.30.50.5-0.10.10.10.10.60.7-1.00.5-1.3-1.5
Condit. Reinf. active responses1.11.53.30.5-1.8-1.4-1.4-1.5-1.61.50.8-0.21.4-0.70.1
Condit. Reinf. inactive responses0.91.13.30.3-1.8-1.1-1.2-1.3-1.50.80.10.40.80.41.4
Condit. Reinf. lever presses2.53.56.0-1.2-1.0-2.3-2.2-2.3-2.41.81.9-1.12.2-1.9-1.1
Condit. Reinf. lever reinforcers received0.81.22.90.5-1.7-1.3-1.2-1.3-1.41.40.60.11.2-0.50.2
Conditioned reinforcement - actives0.10.10.3-0.40.60.20.30.10.1-0.4-0.3-0.2-0.30.1-0.2
Conditioned reinforcement - inactives0.70.81.4-1.10.6-0.9-1.2-0.8-0.80.31.0-1.00.7-1.0-0.5
Conditioned locomotion0.60.71.60.41.3-0.10.81.11.1-0.4-0.61.0-0.50.21.1
Patch foraging indifference point 0 sec0.50.73.81.9-0.20.31.00.71.00.2-0.51.1-0.2-0.10.9
Patch foraging indifference point AUC0.60.72.6-1.50.4-0.9-0.8-0.8-0.9-0.20.1-1.60.1-0.7-0.9
Delay disc. indifference point, 0s delay1.92.112.41.2-2.40.10.10.50.40.3-1.03.5-0.01.21.5
Delay disc. indifference point, 16s delay0.60.62.8-0.21.70.50.20.60.8-0.20.7-0.6-0.2-0.6-1.3
Delay disc. indifference point, 2s delay1.51.710.21.2-1.7-0.9-0.40.1-0.01.00.03.20.80.11.7
Delay disc. indifference point, 24s delay0.60.63.9-0.32.00.20.20.80.8-0.20.9-0.1-0.1-0.8-0.8
Delay disc. indifference point, 4s delay1.01.15.71.3-1.7-0.5-0.3-0.10.01.20.32.40.80.00.4
Delay disc. indifference point, 8s delay0.91.06.80.01.2-0.20.41.11.1-0.10.32.6-0.0-0.30.9
Indifference point function ln k0.30.51.60.9-0.10.60.70.50.5-0.2-0.51.1-0.30.71.2
Indifference point function log k0.30.51.60.9-0.10.60.70.50.5-0.2-0.51.1-0.30.71.2
Patch foraging total patch changes 0 sec0.40.62.91.7-0.20.30.90.70.90.1-0.41.0-0.2-0.10.8
Patch foraging total patch changes 12 sec0.30.30.90.60.50.60.60.81.0-0.3-0.40.4-0.50.0-0.8
Patch foraging total patch changes 18 sec0.20.21.11.0-0.3-0.1-0.00.10.10.50.1-0.40.2-0.6-0.6
Patch foraging total patch changes 24 sec0.10.10.80.9-0.6-0.20.20.10.00.3-0.40.1-0.0-0.1-0.4
Patch foraging total patch changes 6 sec0.10.20.50.7-0.4-0.5-0.3-0.30.10.50.1-0.30.4-0.5-0.2
Patch foraging time to switch 0 sec0.40.71.91.10.61.40.61.11.20.10.20.6-0.30.4-1.0
Patch foraging water rate 0 sec0.50.81.9-0.6-0.2-1.4-0.7-1.1-1.20.60.7-0.90.9-1.3-0.2
Patch foraging water rate 12 sec0.30.52.61.6-1.40.30.5-0.0-0.10.4-0.50.10.00.50.4
Patch foraging water rate 18 sec0.20.31.1-0.3-0.4-1.0-0.4-0.4-0.40.2-0.10.70.4-0.40.8
Patch foraging water rate 24 sec0.20.31.31.1-1.10.40.3-0.1-0.20.1-0.70.1-0.20.70.4
Patch foraging water rate 6 sec0.81.15.61.6-2.4-0.6-0.7-1.1-1.11.20.0-0.20.80.20.2
Seeking ratio, delayed vs. immediate footshock1.31.53.30.80.91.41.61.81.7-1.0-1.01.0-1.30.80.1
Distance traveled before self-admin0.60.71.2-0.50.90.90.71.01.0-1.1-0.80.2-1.10.70.1
Distance traveled after self-admin1.21.33.2-0.60.71.41.00.91.0-1.8-1.6-0.3-1.71.20.2
Extensor digitorum longus weight2.49.419.4-2.6-1.0-4.4-4.0-3.7-3.72.63.1-2.03.4-3.2-0.8
Bone: elastic displacement0.50.51.61.0-1.2-0.6-0.3-0.3-0.50.6-0.30.90.30.21.3
Bone: elastic work1.72.19.52.0-3.1-1.4-0.9-0.9-0.91.5-0.31.20.90.31.8
Bone: endosteal estimation1.32.85.81.2-2.4-1.8-1.7-1.6-1.92.31.4-0.62.1-1.2-0.2
Bone: endosteal perimeter1.32.87.91.6-2.8-1.6-1.8-1.7-1.52.41.1-0.71.9-0.7-0.5
Epididymis fat weight0.40.92.01.10.51.41.21.41.3-0.4-0.4-0.1-0.90.4-1.1
Delta time in closed arm before/after self-admin0.50.51.81.3-1.10.1-0.5-0.7-0.70.80.4-0.20.60.10.2
Delta time in open arm before/after self-admin0.20.20.8-0.6-0.3-0.60.2-0.0-0.0-0.1-0.30.7-0.00.20.9
Diff in mean of infusions in LGA sessions0.80.92.5-0.2-0.2-1.6-0.9-0.5-0.51.00.91.01.2-1.00.9
Delay discount exponential model param0.60.64.3-0.4-0.50.5-0.0-0.6-0.6-0.6-0.8-2.1-0.50.6-0.2
Extinction: sum of active levers before priming1.11.13.5-1.91.7-1.6-0.6-0.1-0.0-0.10.80.40.6-1.11.4
Active lever presses in extinction session 60.40.40.70.5-0.1-0.6-0.7-0.8-0.70.80.6-0.50.8-0.6-0.3
Bone: final force1.62.611.32.7-3.4-1.3-0.9-0.7-0.92.20.31.11.30.11.0
Bone: final moment1.62.612.22.8-3.5-1.3-0.8-0.7-0.82.0-0.01.11.20.21.2
Food consumed during 24 hour testing period0.60.71.9-0.61.40.71.11.10.9-1.1-0.5-0.4-0.9-0.0-0.5
Glucose0.61.02.31.0-0.1-0.3-0.5-0.5-0.31.41.5-0.91.1-1.3-1.5
Heart weight0.20.30.80.6-0.3-0.20.1-0.2-0.60.60.8-0.90.6-0.5-0.3
Delay discount hyperbolic model param0.70.85.5-0.5-0.00.70.2-0.3-0.4-0.9-0.9-2.4-0.80.7-0.3
Intermittent access intake day 1-15 change0.20.20.6-0.10.7-0.3-0.2-0.2-0.20.40.80.30.5-0.5-0.5
Intermittent access intake escalation0.20.20.5-0.50.6-0.3-0.6-0.4-0.40.20.70.00.5-0.5-0.4
Intermittent access intake escalation 20.10.10.4-0.30.40.40.30.10.1-0.30.0-0.1-0.20.1-0.6
Intermitt. access day 1 inactive lever presses1.11.24.3-2.10.7-0.8-0.8-0.9-0.9-0.30.7-1.90.3-1.0-1.0
Intermitt. access day 15 inactive lever presses1.61.86.2-2.5-0.6-0.7-1.0-1.8-1.8-0.60.3-2.40.3-0.4-0.1
Intermitt. access escalation Index0.90.83.6-1.90.3-0.30.0-0.1-0.1-1.0-0.60.4-0.50.51.9
Intermittent access day 1 total infusions0.50.61.0-0.50.5-0.7-0.7-0.7-0.70.61.0-0.60.8-1.0-1.0
Intermittent access day 15 total infusions0.50.61.6-1.11.3-0.7-0.7-0.5-0.50.31.0-0.20.6-0.9-0.7
Intermittent access terminal intake (last 3 days)0.40.41.0-1.00.5-0.6-0.6-0.8-0.80.20.6-0.30.6-0.6-0.6
Intermittent access total infusions0.30.31.1-1.00.5-0.7-0.5-0.6-0.60.10.5-0.20.5-0.5-0.1
Intermittent access day 1 locomotion0.20.20.9-0.50.9-0.3-0.2-0.2-0.20.10.5-0.40.3-0.6-0.6
Intermittent access day 15 total locomotion0.30.31.60.11.3-0.20.20.30.30.40.60.30.3-0.6-0.7
Intermittent access total locomotion0.20.31.2-0.21.1-0.6-0.1-0.1-0.10.40.60.30.5-0.7-0.3
Intermittent access standard deviation1.51.54.30.10.91.72.11.41.4-1.3-0.9-0.1-1.40.6-1.2
Left kidney weight0.30.91.71.0-0.40.71.31.31.1-0.6-1.01.2-0.80.90.9
Right kidney weight0.30.81.50.0-0.30.60.91.20.9-0.9-1.11.2-0.90.91.0
Cocaine induced anxiety1.31.53.21.1-0.31.71.81.21.2-1.0-1.51.0-1.41.40.1
Post-drug Anxiety0.40.51.3-0.70.50.90.80.50.5-1.1-0.6-0.3-0.90.7-0.1
Baseline Anxiety3.43.76.0-2.20.2-2.4-2.5-2.1-2.11.22.0-2.31.8-2.0-0.7
Tail length0.20.51.30.90.30.70.80.71.1-0.5-0.50.1-0.70.80.9
Length with tail0.20.61.90.0-1.1-1.1-0.7-1.0-0.80.50.20.00.6-0.01.4
Length without tail0.91.94.9-0.4-2.0-1.8-1.6-1.9-2.21.10.6-0.11.4-0.60.8
Times rat made contact with spout1.01.12.61.40.11.51.61.21.2-0.7-1.0-0.3-1.10.8-0.4
Lifetime Intake0.20.20.6-0.60.1-0.4-0.8-0.7-0.70.10.3-0.50.4-0.2-0.1
Liver weight, left0.20.40.7-0.1-0.2-0.6-0.8-0.2-0.50.80.80.20.7-0.7-0.8
Liver weight, right0.91.52.8-0.2-1.4-1.2-1.7-1.4-1.61.41.0-0.91.3-0.8-1.0
Locomotor activity0.50.71.3-0.1-0.9-1.1-0.8-1.1-1.20.90.9-0.21.1-0.70.2
Locomotor testing distance1.22.13.2-0.3-0.9-1.7-1.5-1.7-1.81.51.7-1.31.8-1.5-0.7
Locomotor testing rearing0.71.14.11.2-2.0-0.6-0.7-1.0-1.31.40.50.41.1-0.0-0.2
Locomotion in novel chamber3.23.97.5-0.90.91.41.82.11.7-2.5-2.42.2-2.22.02.7
Locomotion in novel chamber post-restriction0.80.92.7-0.3-0.40.50.60.80.5-1.0-1.11.5-0.81.21.7
Fecal boli incidents, locomotor time 11.11.25.5-0.62.3-0.20.41.31.4-0.50.61.9-0.2-0.80.5
Change in fecal boli incidents, locomotor task1.00.92.21.50.41.41.51.21.0-0.3-0.7-0.0-0.80.7-0.4
Time >=10cm from walls, locomotor time 12.22.33.50.71.71.71.91.81.8-1.6-1.40.5-1.81.41.2
Bouts of movement, locomotor time 10.50.64.80.0-0.3-0.3-0.3-0.2-0.1-0.4-0.90.2-0.30.92.2
Total resting periods, locomotor time 10.70.74.00.7-0.50.30.10.20.4-0.5-1.20.3-0.61.32.0
Rest time, locomotor task time 11.01.13.01.4-1.70.5-0.0-0.10.3-0.1-1.30.7-0.41.51.7
Distance moved, locomotor task time 11.01.13.2-1.11.8-0.40.10.2-0.20.11.4-0.70.4-1.7-1.7
Vertical activity count, locomotor time 10.70.73.3-1.81.3-0.5-0.3-0.2-0.5-0.30.9-0.60.2-1.0-0.9
Time >=10cm from walls, locomotor time 20.80.93.60.2-0.40.70.60.40.7-0.7-0.91.9-0.61.21.4
Bouts of movement, locomotor time 20.70.82.2-1.5-0.60.1-0.1-0.7-0.7-1.0-0.9-0.1-0.61.21.5
Total resting periods, locomotor time 20.60.71.3-1.0-1.2-0.0-0.3-0.9-1.0-0.6-0.8-0.6-0.31.11.1
Rest time, locomotor task time 21.11.25.71.9-2.40.0-0.2-0.5-0.40.6-1.0-1.00.11.11.1
Distance moved, locomotor task time 20.60.72.5-1.01.6-0.20.20.40.3-0.01.11.10.3-1.1-0.8
Vertical activity count, locomotor time 20.30.31.4-1.01.20.20.10.30.2-0.40.50.4-0.1-0.4-0.5
Light reinforcement 10.71.24.2-0.41.8-1.0-0.2-0.20.20.81.6-0.61.0-2.0-1.1
Light reinforcement 21.01.46.9-2.52.6-0.60.20.30.4-0.90.7-0.7-0.2-1.0-0.4
Bone: marrow area1.22.75.91.2-2.4-1.7-1.7-1.6-1.92.31.4-0.62.0-1.1-0.2
Bone: maximum diameter0.71.37.02.6-2.30.1-0.3-0.5-0.11.50.2-0.30.70.2-0.4
Bone: maximum force1.52.79.22.0-3.0-1.8-1.4-1.2-1.42.30.80.41.7-0.50.8
Bone: maximum moment1.42.49.22.0-3.0-1.7-1.2-1.1-1.22.10.50.51.5-0.41.0
Mean time between licks in bursts3.24.57.1-2.70.1-2.6-2.4-2.4-2.41.42.4-1.82.2-2.3-1.3
Mean num. licks in bursts1.41.66.0-1.22.40.91.61.01.1-1.7-0.7-1.2-1.40.3-0.2
Cd content in liver0.80.91.7-0.71.00.70.61.01.1-1.3-0.90.8-1.11.00.8
Co content in liver0.60.71.7-1.30.5-0.7-0.8-1.0-0.90.10.8-1.30.6-0.8-0.4
Cu content in liver0.70.81.9-0.1-0.2-0.9-1.1-1.0-0.81.01.4-0.71.2-1.0-0.2
Fe content in liver0.60.82.81.70.11.21.21.21.20.20.10.1-0.3-0.1-0.9
K content in liver0.90.91.7-0.4-1.1-1.3-1.3-1.3-1.30.70.5-0.11.0-0.20.6
Mg content in liver1.41.42.6-0.9-0.4-1.4-1.6-1.6-1.61.01.4-0.71.4-1.1-0.2
Mn content in liver0.40.51.30.6-0.2-0.5-0.4-0.4-0.41.01.0-0.30.9-1.2-1.0
Na content in liver0.60.62.20.7-1.5-0.6-0.8-0.7-0.60.90.30.80.70.40.7
Rb content in liver0.50.71.8-0.21.2-0.4-0.1-0.10.00.41.2-1.30.6-1.3-1.0
Se content in liver0.70.92.00.51.21.31.31.31.4-0.6-0.20.1-0.80.0-0.9
Sr content in liver1.71.52.90.00.41.51.31.31.3-1.4-1.61.0-1.61.70.6
Zn content in liver0.40.51.8-0.91.30.60.60.30.5-0.8-0.2-0.9-0.70.0-0.3
Bone: minimum diameter3.05.611.41.8-3.3-2.6-2.5-2.6-2.43.42.2-0.82.9-1.7-0.0
Time in familiar zone, hab. session 11.21.12.51.00.11.61.41.31.3-0.8-1.10.7-1.21.2-0.3
Time in novel zone, hab. session 10.70.71.20.5-0.6-1.0-0.9-0.7-0.71.10.90.31.1-0.80.8
Total zone transitions, hab. session 11.01.42.9-1.10.2-1.7-1.6-1.3-1.11.01.5-0.41.4-1.5-0.7
Total locomotion distance, hab. session 10.60.83.6-1.90.8-1.0-1.0-1.0-0.8-0.10.7-0.80.5-0.70.0
Locomotion velocity, hab. session 10.91.37.0-2.61.1-1.1-1.0-1.1-1.0-0.40.7-1.20.4-0.8-0.2
Time in familiar zone, hab. session 25.65.89.22.3-0.42.82.82.62.6-1.7-3.02.5-2.52.91.3
Time in novel zone, hab. session 23.83.87.0-0.8-0.4-2.3-2.4-2.2-2.12.02.6-1.52.4-2.3-0.4
Total zone transitions, hab. session 20.50.62.0-1.4-0.2-1.2-1.1-1.0-1.00.30.5-0.10.6-0.40.2
Total locomotion distance, hab. session 20.91.13.8-1.90.9-1.1-1.0-1.1-1.00.10.9-1.50.7-1.1-0.5
Locomotion velocity, hab. session 21.01.35.4-2.31.0-1.2-1.0-1.1-1.1-0.10.8-1.50.5-1.0-0.5
Novel to familiar place preference ratio1.01.12.8-0.7-1.1-1.4-1.3-1.4-1.70.60.5-0.80.9-0.30.8
Novelty place preference0.90.92.4-0.5-1.3-1.2-1.1-1.3-1.50.40.2-0.40.80.01.2
Time in novel zone, NPP test1.01.02.3-0.2-1.5-1.2-1.1-1.2-1.50.60.2-0.10.80.11.4
Total zone transitions, NPP test0.71.04.7-2.20.4-1.3-1.1-1.2-1.1-0.10.4-1.00.5-0.50.1
Total locomotion distance, NPP test0.70.95.5-2.30.7-0.9-0.7-1.0-0.7-0.7-0.0-0.9-0.00.10.9
Locomotion velocity, NPP test0.81.27.5-2.71.0-0.8-0.7-0.9-0.7-1.0-0.1-1.1-0.20.00.8
Intraocular pressure0.50.71.4-0.80.80.50.80.91.2-1.1-0.60.6-0.90.50.7
Delta distance traveled before/after self-admin1.41.52.80.50.21.51.41.31.2-1.5-1.70.7-1.61.30.8
Delta ambulatory time before/after self-admin2.22.44.70.4-0.11.81.71.71.6-1.9-2.21.2-2.01.71.0
Parametrial fat weight0.20.52.50.80.10.60.40.81.00.00.01.6-0.20.20.1
Pavlov. Cond. lever latency0.50.62.80.80.50.70.71.10.9-0.2-0.21.7-0.30.40.8
Pavlov. Cond. magazine entry latency0.10.10.40.6-0.40.20.1-0.10.20.2-0.1-0.6-0.00.1-0.1
Pavlov. Cond. change in total contacts0.80.92.8-1.51.60.40.40.20.3-0.9-0.0-1.7-0.6-0.5-1.2
Pavlov. Cond. index score0.10.21.10.0-0.30.30.2-0.10.1-0.3-0.4-1.0-0.30.3-0.5
Pavlov. Cond. latency score0.20.21.3-0.1-0.10.30.2-0.10.1-0.3-0.4-1.1-0.40.3-0.6
Pavlov. Cond. lever contacts0.50.52.6-1.0-0.4-0.6-0.6-1.0-0.9-0.1-0.0-1.60.2-0.0-0.5
Pavlov. Cond. magazine entry number0.20.20.9-0.81.0-0.0-0.00.2-0.1-0.20.40.70.1-0.4-0.0
Pavlov. Cond. intertrial magazine entries1.11.37.0-2.61.5-0.8-1.0-1.0-1.0-0.41.0-0.80.5-1.00.1
Pavlov. Cond. lever-magazine prob. diff.0.20.21.40.0-0.20.30.2-0.10.1-0.2-0.3-1.2-0.30.3-0.7
Pavlov. Cond. response bias0.30.31.1-0.2-0.9-0.5-0.5-0.8-0.60.2-0.3-1.10.10.3-0.2
Pavlov. Cond. lever latency1.41.83.41.00.41.81.71.61.6-1.2-1.50.8-1.51.50.8
Pavlov. Cond. magazine entry latency0.70.84.31.4-2.1-0.3-0.5-0.5-0.50.9-0.30.80.50.60.2
Pavlov. Cond. change in total contacts1.11.52.4-0.5-0.8-1.4-1.5-1.4-1.51.41.4-0.71.5-1.1-0.8
Pavlov. Cond. index score1.11.42.4-0.1-1.5-1.5-1.5-1.5-1.51.30.9-0.41.4-0.6-0.5
Pavlov. Cond. latency score1.11.42.30.1-1.5-1.4-1.5-1.4-1.41.40.9-0.31.4-0.6-0.4
Pavlov. Cond. lever contacts0.70.91.6-1.1-0.2-1.3-1.2-1.1-1.20.71.1-0.51.0-1.0-0.7
Pavlov. Cond. magazine entry number0.30.31.5-0.91.20.20.40.30.3-0.70.1-0.3-0.4-0.30.3
Pavlov. Cond. intertrial magazine entries0.20.20.7-0.80.70.40.20.1-0.0-0.7-0.0-0.2-0.40.20.6
Pavlov. Cond. lever-magazine prob. diff.0.81.01.7-0.1-1.1-1.3-1.3-1.2-1.21.10.8-0.31.2-0.6-0.6
Pavlov. Cond. response bias0.60.91.6-0.6-0.7-1.3-1.2-1.1-1.11.00.9-0.21.1-0.8-0.6
Time in closed arm before self-admin0.50.51.5-0.0-0.60.60.90.40.4-0.6-1.20.9-0.80.90.0
Time in closed arm after self-admin0.30.30.80.3-0.10.90.70.50.4-0.4-0.60.9-0.50.6-0.3
Time in open arm before self-admin1.21.42.90.4-0.0-0.8-1.5-1.0-1.01.31.7-1.41.3-1.3-1.1
Time in open arm after self-admin0.50.51.20.4-1.1-0.8-0.9-0.8-0.70.90.6-0.10.9-0.40.5
Bone: periosteal estimation1.83.79.92.1-3.2-1.9-1.8-1.8-1.92.81.4-0.72.2-1.2-0.1
Bone: periosteal perimeter1.32.29.12.5-3.0-1.1-1.2-1.2-0.92.10.50.01.3-0.20.3
Bone: post-yield work2.12.84.0-1.1-0.4-1.9-1.8-2.0-1.91.41.7-2.01.8-1.9-1.3
Progressive ratio test 1 active lever presses0.10.10.3-0.20.5-0.5-0.4-0.1-0.10.20.30.50.3-0.20.5
Progressive ratio test 1 breakpoint0.10.10.3-0.30.3-0.5-0.6-0.3-0.30.20.40.20.4-0.20.3
Progressive ratio test 1 inactive lever presses0.70.82.5-1.61.3-1.0-1.0-0.4-0.4-0.10.8-1.00.4-0.9-0.0
Progressive ratio test 2 active lever presses1.31.43.9-0.01.8-1.1-0.6-0.0-0.01.32.00.41.3-1.7-1.3
Progressive ratio test 2 breakpoint1.41.54.40.21.4-1.1-0.6-0.3-0.31.52.10.41.5-1.7-1.5
Progressive ratio test 2 inactive lever presses0.20.31.8-0.61.3-0.30.40.40.4-0.30.20.3-0.1-0.40.0
Incentive Sensitization - Responses2.02.05.90.21.5-1.5-1.0-0.4-0.41.82.40.61.8-1.9-1.4
Incentive Sensitization - Breakpoint1.81.95.40.11.6-1.4-0.9-0.3-0.31.72.30.61.7-1.8-1.3
Sum of active levers in priming session hrs 5-61.31.23.9-2.01.8-0.80.0-0.3-0.2-0.40.9-2.00.2-1.3-0.7
Progressive ratio0.40.41.00.80.1-0.3-0.5-0.2-0.11.01.00.10.8-0.7-1.0
Food seeking constrained by brief footshock0.60.84.40.1-0.00.00.40.90.7-0.4-0.62.1-0.40.61.6
Seeking ratio, punishment vs. effort0.30.31.6-0.90.1-0.20.30.10.0-0.8-0.70.1-0.50.51.3
Retroperitoneal fat weight0.20.83.70.20.4-0.4-0.00.30.11.01.30.40.8-1.4-1.9
Reaction time number correct2.02.95.72.4-1.12.12.11.91.7-0.7-1.81.7-1.42.00.8
Reaction time mean minus median2.43.24.9-1.30.1-1.8-2.2-1.9-1.91.62.2-1.81.8-2.1-1.8
Reaction time mean minus median AUC4.86.39.5-2.20.2-2.5-3.1-2.7-2.62.03.0-2.82.5-2.9-2.3
Reaction time num false alarms1.01.47.52.7-1.4-0.6-0.1-0.00.21.80.61.21.1-0.30.5
Reaction time num false alarms AUC1.01.47.42.7-1.7-0.5-0.2-0.00.11.70.51.41.0-0.00.3
Reaction time trials correct on left2.02.95.72.4-1.12.12.11.91.7-0.7-1.81.7-1.42.00.8
Reaction time trials on left1.92.75.62.4-1.12.01.91.81.7-0.7-1.71.6-1.41.90.8
Reaction time mean1.82.65.4-1.3-0.0-1.4-2.2-1.9-1.81.11.6-2.31.5-1.5-1.2
Reaction time mean AUC2.83.87.4-1.7-0.0-2.0-2.7-2.4-2.21.42.0-2.61.8-1.9-1.2
Median of all reaction times1.21.74.2-1.1-0.1-1.0-1.8-1.6-1.50.81.2-2.11.1-1.0-0.8
Reaction time omissions3.54.89.2-1.70.9-2.3-2.6-2.2-1.91.83.0-2.32.4-2.8-1.8
Reaction time false alarm rate1.01.43.81.4-0.7-1.5-1.0-0.8-0.61.91.50.41.6-1.2-0.2
Reaction time premature initiation rate0.50.62.41.1-1.50.70.30.3-0.0-0.0-1.10.7-0.51.10.2
Reaction time premature initiations1.62.24.92.2-2.01.61.21.10.8-0.3-1.81.7-1.02.00.6
Std. dev. reaction times3.24.59.6-1.2-1.1-2.2-3.1-2.9-2.81.92.0-2.22.1-1.8-1.2
Reaction time trials completed1.92.75.62.4-1.12.01.91.81.7-0.7-1.71.6-1.41.90.8
Reaction time trials AUC1.82.65.32.3-1.02.01.91.71.7-0.7-1.61.6-1.31.80.8
Run reversals in cocaine runway, females0.50.52.8-1.71.1-0.4-0.60.20.0-0.70.0-0.1-0.3-0.20.7
Run reversals in cocaine runway, males0.20.20.4-0.60.50.10.60.6-0.0-0.7-0.40.1-0.5-0.00.3
Latency to leave start box in cocaine runway0.60.63.30.30.90.60.30.1-0.00.00.5-1.4-0.1-0.6-1.8
Latency to leave start box in cocaine runway, F0.50.51.31.01.10.70.70.60.6-0.10.3-0.8-0.3-0.3-1.0
Latency to leave start box in cocaine runway, M0.30.31.4-0.90.20.2-0.2-0.4-0.6-0.20.2-0.60.0-0.3-1.2
Std. dev. time between licks in bursts5.46.410.0-1.1-0.6-3.0-2.7-2.9-2.72.63.2-2.13.1-3.0-2.0
Total sessions with >9 infusions0.40.51.7-0.10.7-0.6-1.3-0.7-0.70.40.7-0.80.6-0.6-0.0
Short access day 1 total inactive lever presses0.30.41.0-0.90.6-1.0-0.8-0.5-0.5-0.10.1-0.30.2-0.50.7
Short access day 10 total inactive lever presses0.40.41.9-0.10.0-0.5-0.7-0.4-0.40.40.6-1.40.4-0.7-0.8
Short access day 1 total infusions0.30.41.1-1.00.50.3-0.6-0.2-0.2-0.9-0.5-1.1-0.50.40.2
Short access day 10 total infusions0.30.41.4-0.8-0.6-0.4-0.7-0.8-0.8-0.2-0.20.20.10.41.2
Short access total infusions0.40.51.4-0.3-0.6-0.5-1.2-1.1-1.10.40.3-0.80.6-0.10.1
Short access day 1 locomotion0.20.20.50.6-0.7-0.0-0.5-0.6-0.60.3-0.2-0.40.20.2-0.1
Short access day 10 total locomotion0.91.02.20.60.41.51.41.11.1-1.0-1.3-0.0-1.31.1-0.3
Short access total locomotion0.00.00.10.3-0.00.2-0.3-0.1-0.10.1-0.20.1-0.00.3-0.1
One hour access (0.3 mA shock)0.30.42.1-0.21.5-0.40.30.60.60.20.70.50.2-0.6-0.1
Compulsive drug intake0.70.72.41.6-0.7-0.60.50.30.31.30.71.40.8-0.5-0.0
One hour access (shock baseline)0.30.42.1-1.11.50.3-0.20.20.2-0.8-0.1-0.7-0.50.0-0.2
Social response proportion0.30.43.1-0.3-0.3-0.7-0.2-0.4-0.2-0.1-0.30.50.10.11.8
Social responses0.50.72.31.5-1.5-0.2-0.1-0.1-0.00.7-0.31.30.30.41.0
Social time0.20.30.80.00.6-0.20.30.70.7-0.10.00.9-0.1-0.30.8
Soleus weight0.31.02.31.4-1.00.70.80.90.8-0.4-1.21.1-0.71.51.1
Bone: stiffness0.20.31.00.5-1.0-0.4-0.5-0.2-0.30.60.20.90.50.20.6
Tibialis anterior weight0.20.71.50.60.40.81.21.11.2-0.7-0.80.7-0.90.50.3
Time to tail flick, vehicle, before self-admin0.30.31.21.1-0.90.10.2-0.2-0.10.60.3-0.20.4-0.4-1.1
Time to tail flick, vehicle, after self-admin2.72.95.5-1.41.3-2.2-1.5-1.6-1.51.22.3-1.91.9-2.3-0.3
Time to tail flick, test, before self-admin1.01.03.6-1.01.9-1.2-0.6-0.6-0.70.41.1-0.80.7-1.4-0.5
Time to tail flick, test, after self-admin1.01.12.7-1.00.90.41.61.00.9-1.3-1.10.9-1.00.51.2
Delta time to tail flick, vehicle, before/after SA1.21.24.2-2.01.8-1.2-0.9-0.6-0.6-0.30.8-1.40.4-0.81.1
Delta time to tail flick, test, before/after SA1.11.03.20.10.21.11.81.31.4-1.0-0.80.9-1.00.70.3
Tibia length0.10.41.7-1.0-0.1-0.5-0.4-0.5-0.4-0.5-0.3-0.1-0.20.51.3
Ambulatory time before self-admin0.10.10.4-0.20.60.1-0.10.30.3-0.00.2-0.2-0.1-0.1-0.6
Ambulatory time after self-admin2.12.44.70.00.22.01.71.61.6-1.9-2.20.7-2.11.70.3
Bone: tissue strength0.20.20.7-0.80.2-0.10.10.1-0.2-0.6-0.3-0.1-0.30.30.8
Total heroin consumption0.30.41.7-0.2-0.3-0.20.80.50.4-0.3-0.70.9-0.30.41.3
Bone: trabecular number3.55.533.45.8-3.71.51.51.41.31.3-1.32.0-0.31.70.9
Bone: trabecular spacing1.92.518.5-4.32.0-0.8-1.0-1.1-1.0-1.40.2-1.2-0.2-0.1-0.3
Bone: trabecular thickness5.26.222.14.7-1.92.62.82.72.6-0.3-2.12.6-1.72.41.0
Bone: trabecular tissue density0.81.15.1-1.62.30.80.90.80.8-1.4-0.1-0.1-0.90.00.1
Water consumed over 24 hours0.50.64.02.0-1.20.40.60.50.50.5-0.50.2-0.10.4-0.3
Number of responses in last shaping day0.50.51.5-0.31.20.80.90.70.7-0.7-0.1-0.5-0.6-0.0-1.1