Hub : Genes

Mfsd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Mfsd1 0.23 0.1 0.0e+00 0.1 0.13 0.12 0.13 3.5e-11 2.7e-14 2.8e-13 5.1e-14
2 IC gene expression Mfsd1 0.12 0.06 5.7e-06 0.1 0.13 0.11 0.12 6.3e-05 6.0e-06 2.6e-05 1.6e-05
3 BLA gene expression Mfsd1 0.07 0.04 8.1e-03 0.03 0.02 0.01 0.03 1.8e-02 2.6e-02 5.3e-02 1.5e-02
4 Adipose mRNA stability Mfsd1 0.1 0.06 2.2e-06 0.01 0.04 0.04 0.03 4.7e-02 7.2e-05 2.1e-05 2.1e-04
5 Brain mRNA stability Mfsd1 0.06 0.03 1.0e-05 0.05 0.04 0.04 0.04 1.2e-05 1.3e-04 1.5e-04 1.1e-04
6 NAcc gene expression Mfsd1 0.06 0.03 8.6e-14 0.1 0.09 0.09 0.09 1.4e-14 3.4e-13 5.2e-13 4.0e-13
7 NAcc mRNA stability Mfsd1 0.03 0.02 6.1e-04 0.02 0.02 0.02 0.02 1.1e-04 1.6e-03 7.9e-04 5.1e-04
8 LHb mRNA stability Mfsd1 0.24 0.13 1.1e-03 0.07 0.09 0.1 0.08 8.1e-03 4.6e-03 1.9e-03 7.2e-03
9 BLA mRNA stability Mfsd1 0.08 0.05 2.2e-03 0.07 0.03 0.04 0.06 1.2e-04 1.3e-02 4.8e-03 3.7e-04
10 IL mRNA stability Mfsd1 0.19 0.11 6.4e-03 -0.01 0.04 0 0.01 5.0e-01 4.9e-02 2.3e-01 1.6e-01
11 Brain gene expression Mfsd1 0.18 0.08 5.9e-15 0.18 0.16 0.17 0.17 2.5e-16 1.1e-14 2.6e-15 2.0e-15
12 Liver mRNA stability Mfsd1 0.05 0.03 1.7e-04 0.04 0.04 0.01 0.03 8.6e-05 4.5e-05 7.2e-03 2.1e-04
13 PL gene expression Mfsd1 0.1 0.04 3.8e-11 0.1 0.09 0.1 0.1 1.6e-11 4.8e-10 3.5e-11 8.3e-11
14 IL gene expression Mfsd1 0.37 0.16 2.1e-03 0.01 0.02 0.03 0.04 1.5e-01 9.1e-02 7.9e-02 4.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density3.05.226.95.2-3.7-2.82.3-1.4-1.5-1.5-2.2-1.11.3-1.5-0.3-1.4-0.8
Area under the delay curve0.20.30.50.50.20.30.40.50.50.5-0.6-0.60.70.70.60.60.5
BMI with tail0.93.35.40.61.41.61.72.12.32.30.11.52.32.02.22.31.1
BMI without tail0.82.35.92.4-0.31.10.30.60.50.5-2.2-0.22.12.21.41.82.2
Body weight0.62.74.60.11.71.91.32.01.91.9-0.51.31.82.21.92.11.2
Weight adjusted by age0.30.42.21.5-0.5-0.10.90.60.40.4-0.60.21.00.30.50.40.3
Bone surface1.42.514.03.7-1.7-1.32.80.60.40.4-0.30.72.3-0.31.1-0.2-0.8
Bone volume2.03.619.54.4-2.6-2.33.1-0.1-0.4-0.4-1.10.01.8-1.10.5-1.1-1.3
Breakpoint value in progressive ratio session0.20.20.8-0.90.60.4-0.50.30.30.30.90.60.00.10.30.30.1
Number of licking bursts0.50.94.62.1-0.9-0.81.60.30.30.30.20.51.5-0.00.9-0.1-0.5
Context. condit. distance diff. score2.12.66.02.0-2.4-1.7-0.5-1.8-1.8-1.8-1.7-2.0-0.8-1.4-1.5-1.2-0.1
Locomotion velocity, session 10.10.10.5-0.4-0.1-0.1-0.7-0.2-0.5-0.50.2-0.2-0.5-0.3-0.4-0.4-0.1
Locomotion distance, session 10.60.72.6-1.31.00.5-0.01.00.90.91.61.10.10.00.40.1-0.6
Locomotion velocity, session 20.40.52.20.2-0.4-1.10.50.1-0.2-0.20.40.2-0.2-0.9-0.3-1.2-1.5
Locomotion distance, session 21.11.63.2-1.71.80.80.51.51.61.61.81.80.40.30.90.4-0.8
Locomotion velocity, session 30.91.02.51.10.1-0.11.51.11.01.00.81.41.60.41.30.3-0.5
Locomotion distance, session 30.80.95.02.2-1.3-0.81.4-0.3-0.3-0.3-1.0-0.10.9-0.40.3-0.3-0.1
Stereotopy head waving bouts, day 30.30.41.71.3-1.0-0.90.6-0.2-0.2-0.2-0.0-0.20.4-0.6-0.1-0.6-0.5
Stereotopy head waving duration, day 30.50.62.21.5-1.2-1.10.7-0.3-0.4-0.4-0.4-0.50.3-0.8-0.2-0.8-0.7
Locomotion velocity, session 70.40.42.2-1.50.80.5-0.60.20.50.50.90.3-0.6-0.3-0.20.1-0.2
Locomotion distance, session 70.81.03.0-0.9-0.4-0.2-1.7-1.3-1.1-1.1-0.3-0.9-1.6-0.8-1.4-0.60.2
Stereotopy head waving bouts, day 70.60.61.8-0.10.50.00.91.31.01.01.40.70.80.20.7-0.0-0.8
Stereotopy head waving duration, day 71.41.74.1-0.21.10.51.42.01.71.71.81.41.50.81.50.5-0.7
Locomotion velocity, session 80.40.50.9-0.10.60.50.20.90.70.70.90.70.80.70.80.60.1
Locomotion distance, session 80.10.10.6-0.60.3-0.1-0.10.30.30.30.70.6-0.2-0.3-0.0-0.2-0.5
Degree of sensitization distance1.91.98.3-2.90.90.9-2.9-0.7-0.6-0.60.8-0.7-2.1-0.0-1.3-0.00.5
Degree of sensitization stereotypy0.50.62.0-0.90.80.20.41.10.90.91.40.70.30.10.4-0.1-0.9
Conditioned locomotion0.40.41.00.40.50.21.00.90.80.80.40.60.90.50.90.3-0.2
Cocaine response after cond. corrected0.60.72.1-0.80.50.9-1.3-0.6-0.5-0.5-1.0-0.8-0.70.7-0.40.81.4
Cocaine response after cond. not corrected0.60.72.0-0.91.01.3-0.80.20.30.3-0.10.20.01.30.41.31.4
Cocaine response before conditioning0.50.61.60.8-0.10.10.70.60.60.61.01.21.30.51.00.40.0
Saline control response2.02.66.51.40.50.91.91.81.61.61.12.12.61.52.21.60.7
Bone: connectivity density1.52.314.93.9-2.5-1.51.6-0.7-0.7-0.7-1.5-0.61.4-0.50.2-0.4-0.1
Bone: cortical apparent density4.46.110.70.4-2.2-1.6-2.0-3.3-3.3-3.3-2.9-3.1-2.8-2.0-2.9-1.90.2
Bone: cortical area1.21.87.82.8-0.9-0.62.41.21.01.0-0.10.92.20.31.30.4-0.5
Bone: cortical porosity1.92.03.9-1.51.90.90.71.91.61.62.01.90.91.01.40.7-0.5
Bone: cortical porosity2.32.44.9-1.11.90.91.02.21.91.91.92.11.31.21.70.8-0.6
Bone: cortical thickness0.61.05.42.3-1.5-1.21.1-0.3-0.4-0.4-1.1-0.50.7-0.6-0.1-0.5-0.4
Bone: cortical thickness1.21.48.73.0-1.4-0.91.90.30.20.2-0.40.21.80.20.9-0.1-0.4
Bone: cortical tissue density4.35.810.40.4-2.1-1.5-2.0-3.2-3.2-3.2-2.9-3.0-2.7-1.9-2.8-1.80.3
Condit. Reinf. active minus inactive responses3.03.35.3-1.42.32.20.32.02.12.11.72.11.41.91.92.01.0
Condit. Reinf. active-inactive response ratio2.62.74.8-1.52.21.70.52.02.12.11.91.91.11.41.61.40.2
Condit. Reinf. active responses4.55.68.4-1.62.92.90.32.62.82.82.12.61.82.62.42.81.5
Condit. Reinf. inactive responses1.21.53.8-0.71.22.0-1.00.60.90.90.50.70.61.70.91.91.9
Incentive salience index mean1.92.44.6-1.82.12.0-0.31.61.81.81.61.80.71.41.31.60.8
Condit. Reinf. lever presses0.71.04.1-2.01.41.2-1.20.60.80.81.40.9-0.40.40.20.70.4
Condit. Reinf. active minus inactive responses0.81.02.30.70.40.90.31.01.11.10.70.81.51.11.31.40.9
Condit. Reinf. active-inactive response ratio0.50.63.10.6-0.11.0-0.9-0.20.10.1-0.4-0.00.60.90.41.31.7
Condit. Reinf. active responses0.91.32.60.70.50.31.31.41.41.41.31.51.60.71.40.8-0.3
Condit. Reinf. inactive responses0.81.03.70.30.4-0.51.91.21.11.11.01.20.9-0.20.9-0.2-1.4
Condit. Reinf. lever presses2.43.35.7-0.92.01.90.52.12.12.11.82.41.82.02.12.00.8
Condit. Reinf. lever reinforcers received0.71.02.00.60.40.21.21.21.31.31.11.31.40.51.20.7-0.3
Conditioned reinforcement - actives0.10.20.9-0.6-0.1-0.2-1.0-0.3-0.3-0.30.2-0.2-0.6-0.5-0.5-0.2-0.1
Conditioned reinforcement - inactives0.40.61.5-1.11.21.0-0.50.80.80.80.40.90.10.70.50.90.6
Conditioned locomotion0.20.20.60.1-0.3-0.80.2-0.1-0.1-0.1-0.7-0.7-0.6-0.5-0.7-0.3-0.5
Patch foraging indifference point 0 sec0.51.04.52.0-1.2-0.91.4-0.1-0.3-0.3-2.1-0.70.3-0.7-0.20.10.1
Patch foraging indifference point AUC0.50.83.3-1.81.10.8-0.90.80.80.81.40.8-0.40.30.00.50.1
Delay disc. indifference point, 0s delay0.80.93.71.0-0.6-1.21.90.20.20.21.2-0.10.6-0.60.3-0.9-1.7
Delay disc. indifference point, 16s delay0.60.72.8-0.00.10.6-1.5-0.4-0.4-0.4-1.4-0.6-0.20.5-0.20.71.7
Delay disc. indifference point, 2s delay0.80.95.51.10.0-0.52.40.90.90.90.20.11.10.20.9-0.1-1.1
Delay disc. indifference point, 24s delay0.70.82.7-0.40.51.0-1.2-0.1-0.1-0.1-1.7-0.7-0.21.1-0.00.91.5
Delay disc. indifference point, 4s delay0.50.51.61.2-0.3-0.41.30.50.50.50.60.11.20.20.80.0-0.5
Delay disc. indifference point, 8s delay0.20.20.90.00.30.20.10.30.30.3-0.8-1.00.10.40.10.40.3
Indifference point function ln k0.30.51.00.9-0.7-0.71.0-0.7-0.7-0.7-1.0-0.6-0.3-0.9-0.4-0.7-0.4
Indifference point function log k0.30.51.00.9-0.7-0.71.0-0.7-0.7-0.7-1.0-0.6-0.3-0.9-0.4-0.7-0.4
Patch foraging total patch changes 0 sec0.40.84.41.7-0.9-0.71.3-0.1-0.3-0.3-2.1-0.60.3-0.5-0.10.20.2
Patch foraging total patch changes 12 sec0.10.20.60.5-0.7-0.4-0.3-0.2-0.4-0.4-0.8-0.6-0.2-0.0-0.40.10.4
Patch foraging total patch changes 18 sec0.20.31.01.0-0.40.00.40.40.20.2-0.8-0.10.60.50.30.70.6
Patch foraging total patch changes 24 sec0.10.21.01.0-0.7-0.60.60.30.20.2-0.60.10.5-0.40.10.1-0.2
Patch foraging total patch changes 6 sec0.20.40.90.70.00.11.00.80.70.7-0.70.50.60.20.50.70.3
Patch foraging time to switch 0 sec0.40.81.51.2-1.1-0.3-1.0-1.0-1.2-1.2-0.9-1.10.00.3-0.4-0.40.8
Patch foraging water rate 0 sec0.51.12.0-0.71.31.10.71.31.41.40.31.20.70.81.01.40.4
Patch foraging water rate 12 sec0.30.72.61.6-1.1-1.21.3-0.6-0.6-0.6-0.8-0.00.4-0.7-0.0-0.7-0.8
Patch foraging water rate 18 sec0.10.20.6-0.20.4-0.00.70.50.70.70.40.10.2-0.50.40.1-0.5
Patch foraging water rate 24 sec0.30.41.01.0-0.9-0.80.6-0.5-0.5-0.50.1-0.00.1-0.9-0.1-0.6-0.6
Patch foraging water rate 6 sec0.60.94.11.6-0.5-0.72.00.40.50.5-0.01.01.30.10.9-0.2-1.0
Seeking ratio, delayed vs. immediate footshock1.01.32.70.8-1.4-0.9-0.8-1.4-1.4-1.4-1.2-1.6-1.0-0.7-1.3-0.70.3
Distance traveled before self-admin0.30.41.6-0.9-0.0-0.3-1.3-0.4-0.5-0.50.2-0.5-0.9-0.2-0.8-0.4-0.2
Distance traveled after self-admin1.11.33.0-0.4-1.1-1.2-1.7-1.4-1.4-1.4-0.1-0.9-1.5-0.5-1.5-1.0-0.3
Extensor digitorum longus weight2.610.217.3-2.53.93.11.04.24.14.13.93.52.42.63.13.00.5
Bone: elastic displacement0.30.41.80.8-0.3-0.51.30.50.60.60.10.50.7-0.50.5-0.0-0.6
Bone: elastic work1.21.66.11.9-0.8-1.22.51.01.11.10.70.81.5-0.70.9-0.5-1.6
Bone: endosteal estimation1.12.45.61.40.50.52.01.91.81.80.81.82.41.12.01.1-0.0
Bone: endosteal perimeter1.02.25.81.80.0-0.12.21.71.61.61.21.72.40.81.80.6-0.6
Epididymis fat weight0.20.83.50.8-0.70.1-1.1-0.7-0.7-0.7-1.9-1.4-0.20.6-0.50.31.1
Delta time in closed arm before/after self-admin0.20.10.60.10.40.30.7-0.00.00.0-0.50.80.30.30.50.00.1
Delta time in open arm before/after self-admin0.30.31.3-0.2-0.2-0.70.50.10.10.10.6-0.6-0.4-1.1-0.5-0.6-1.2
Diff in mean of infusions in LGA sessions0.50.61.4-0.10.80.60.91.21.11.10.40.20.80.60.90.80.0
Delay discount exponential model param0.30.40.8-0.3-0.5-0.5-0.4-0.7-0.7-0.70.40.3-0.7-0.9-0.7-0.8-0.5
Extinction: sum of active levers before priming1.01.13.1-1.41.81.30.01.51.41.40.30.10.20.60.71.20.4
Active lever presses in extinction session 60.10.10.30.40.20.00.00.50.40.4-0.30.30.50.40.50.60.4
Bone: final force1.52.48.52.9-1.0-1.22.91.31.21.20.30.82.2-0.21.3-0.2-1.4
Bone: final moment1.52.59.23.0-1.2-1.43.01.21.11.10.30.72.1-0.41.2-0.3-1.5
Food consumed during 24 hour testing period0.40.62.1-0.6-0.20.2-1.4-0.9-0.8-0.8-0.5-0.9-1.1-0.3-0.90.10.7
Glucose0.91.44.01.5-0.01.00.00.3-0.1-0.1-1.40.11.52.01.21.42.0
Heart weight0.60.92.40.10.81.3-0.00.60.60.6-1.50.00.61.20.71.31.5
Delay discount hyperbolic model param0.40.50.9-0.5-0.5-0.5-0.6-0.8-0.8-0.80.30.3-0.9-0.9-0.9-0.8-0.5
Intermittent access intake day 1-15 change0.10.30.7-0.50.80.70.10.70.70.70.40.60.40.30.60.60.3
Intermittent access intake escalation0.10.20.4-0.30.60.50.10.50.50.50.30.40.30.20.50.40.1
Intermittent access intake escalation 20.00.00.10.00.00.2-0.3-0.0-0.0-0.00.10.00.1-0.10.10.10.3
Intermitt. access day 1 inactive lever presses0.52.04.1-2.01.81.9-1.81.01.01.01.11.30.11.60.71.61.5
Intermitt. access day 15 inactive lever presses0.81.65.5-2.31.91.2-0.40.90.90.91.92.2-0.10.80.70.5-0.1
Intermitt. access escalation Index0.60.83.9-2.00.8-0.2-0.40.20.20.21.5-0.1-1.1-0.7-0.6-0.6-1.3
Intermittent access day 1 total infusions0.30.41.4-0.70.80.8-0.80.40.40.40.00.80.21.20.40.80.8
Intermittent access day 15 total infusions0.40.51.3-1.11.00.9-0.90.60.60.60.30.5-0.01.10.30.80.7
Intermittent access terminal intake (last 3 days)0.40.51.1-1.00.90.7-0.60.70.70.70.70.80.20.90.50.60.3
Intermittent access total infusions0.20.21.1-1.10.80.4-0.50.30.30.30.30.5-0.30.60.10.20.0
Intermittent access day 1 locomotion0.10.20.6-0.60.30.3-0.80.00.00.0-0.30.2-0.30.6-0.10.40.6
Intermittent access day 15 total locomotion0.10.10.40.30.10.3-0.40.20.20.2-0.10.10.40.40.30.50.6
Intermittent access total locomotion0.10.10.20.20.10.1-0.00.30.30.3-0.30.20.30.40.30.40.4
Intermittent access standard deviation0.71.53.8-0.5-0.7-0.3-2.0-1.5-1.5-1.5-1.1-1.3-1.6-0.7-1.5-0.60.7
Left kidney weight0.31.55.32.1-1.5-1.01.2-0.7-0.8-0.8-2.3-1.7-0.0-1.0-0.6-0.50.0
Right kidney weight0.20.82.11.5-1.1-1.11.3-0.3-0.4-0.4-1.1-1.00.0-1.2-0.4-0.8-0.7
Cocaine induced anxiety0.40.61.1-0.2-0.7-0.8-0.9-1.0-1.0-1.0-0.1-0.7-1.0-0.2-1.0-0.9-0.5
Post-drug Anxiety0.20.31.0-1.00.2-0.3-0.2-0.2-0.2-0.20.60.4-0.6-0.3-0.4-0.6-1.0
Baseline Anxiety1.31.53.4-1.31.71.30.51.41.41.41.71.80.80.31.20.8-0.1
Tail length0.20.74.31.4-0.8-0.30.1-0.4-0.7-0.7-2.1-1.00.20.2-0.2-0.30.4
Length with tail0.10.30.9-0.40.70.30.90.80.60.60.10.50.20.10.4-0.1-0.7
Length without tail0.41.22.3-1.41.40.31.51.21.21.21.41.30.0-0.30.6-0.1-1.4
Times rat made contact with spout1.41.63.21.4-1.8-0.9-0.7-1.8-1.6-1.6-1.8-1.2-0.7-0.8-1.1-0.70.4
Lifetime Intake0.10.10.7-0.80.60.2-0.30.10.10.10.10.5-0.20.40.00.0-0.1
Liver weight, left1.01.73.8-0.81.40.90.61.81.61.61.91.51.11.21.30.9-0.2
Liver weight, right0.20.41.40.7-0.4-0.70.90.40.30.31.00.30.7-0.20.4-0.5-1.2
Locomotor activity0.40.71.7-0.11.00.61.01.30.90.9-0.01.00.90.91.10.60.0
Locomotor testing distance1.32.34.4-0.31.61.41.12.11.61.60.72.01.61.91.91.40.6
Locomotor testing rearing0.40.82.91.2-0.1-0.21.70.90.50.50.61.21.50.61.2-0.0-0.4
Locomotion in novel chamber1.92.55.2-0.6-1.0-1.80.1-1.3-1.3-1.3-0.3-2.1-2.0-2.3-1.9-1.9-2.0
Locomotion in novel chamber post-restriction0.50.82.3-0.0-0.6-1.30.6-0.7-0.7-0.7-0.4-0.9-0.9-1.2-0.9-1.3-1.5
Fecal boli incidents, locomotor time 10.50.73.1-0.60.60.8-0.80.10.10.1-1.8-1.5-0.60.2-0.40.61.0
Change in fecal boli incidents, locomotor task1.11.12.11.3-1.4-1.0-0.4-1.3-1.3-1.3-1.4-1.1-0.5-0.3-0.9-0.70.1
Time >=10cm from walls, locomotor time 11.92.15.50.7-1.4-1.2-0.5-1.6-1.6-1.6-2.4-1.8-1.5-1.2-1.7-1.2-0.2
Bouts of movement, locomotor time 10.60.73.50.1-0.0-1.01.80.40.40.40.10.0-0.2-1.1-0.2-0.9-1.9
Total resting periods, locomotor time 10.80.93.20.7-0.7-1.31.7-0.1-0.1-0.1-0.2-0.4-0.3-1.4-0.5-1.2-1.8
Rest time, locomotor task time 11.31.64.11.5-1.5-1.81.8-0.7-0.7-0.7-0.1-0.6-0.1-1.3-0.5-1.7-2.0
Distance moved, locomotor task time 10.81.24.8-1.00.91.6-1.90.20.20.2-0.9-0.1-0.11.30.21.52.2
Vertical activity count, locomotor time 10.40.82.8-1.71.11.2-1.60.30.30.3-0.10.3-0.51.10.00.91.1
Time >=10cm from walls, locomotor time 20.30.51.30.1-0.5-1.00.6-0.7-0.7-0.7-0.4-0.5-0.7-0.5-0.6-1.1-1.1
Bouts of movement, locomotor time 20.60.93.7-1.60.5-0.60.1-0.2-0.2-0.21.10.5-1.2-1.0-0.7-1.3-1.9
Total resting periods, locomotor time 20.40.73.2-1.20.4-0.60.5-0.1-0.1-0.11.20.7-0.8-0.8-0.4-1.1-1.8
Rest time, locomotor task time 21.11.35.21.9-1.3-1.42.3-0.0-0.0-0.00.10.50.8-1.10.2-1.1-1.7
Distance moved, locomotor task time 20.50.61.9-0.90.91.1-1.10.20.20.2-0.4-0.4-0.11.10.31.01.4
Vertical activity count, locomotor time 20.20.31.3-1.00.50.4-1.2-0.3-0.3-0.3-0.3-0.4-0.60.6-0.30.10.5
Light reinforcement 10.81.96.1-0.31.21.9-0.51.51.31.3-0.40.00.91.81.02.52.2
Light reinforcement 20.81.25.6-2.41.71.4-1.50.70.60.60.6-0.4-0.90.8-0.20.90.8
Bone: marrow area1.02.25.21.40.40.32.01.81.81.80.81.82.31.01.91.0-0.2
Bone: maximum diameter0.71.38.02.8-1.5-1.21.60.2-0.2-0.2-0.60.31.5-0.10.6-0.5-0.5
Bone: maximum force1.32.48.12.3-0.4-0.62.91.71.61.60.61.22.40.31.60.3-1.0
Bone: maximum moment1.22.18.12.3-0.6-0.82.81.51.41.40.61.12.1-0.11.40.2-1.1
Mean time between licks in bursts2.15.210.9-2.73.32.70.22.72.62.62.32.11.22.52.02.31.0
Mean num. licks in bursts0.91.44.2-1.2-0.20.3-2.1-1.3-1.2-1.2-1.2-1.2-1.8-0.4-1.4-0.20.8
Cd content in liver0.50.51.10.6-0.9-1.0-0.5-0.6-0.5-0.5-0.7-0.6-0.6-1.1-0.8-0.9-0.7
Co content in liver0.50.61.1-0.81.01.0-0.50.80.90.90.80.80.40.90.70.80.5
Cu content in liver0.70.81.4-0.21.10.90.81.11.01.00.31.11.01.11.20.80.3
Fe content in liver0.40.51.41.0-0.80.1-0.7-0.7-0.8-0.8-0.7-0.80.10.6-0.20.41.2
K content in liver1.21.22.8-0.41.00.01.71.51.41.41.11.30.8-0.01.0-0.0-1.1
Mg content in liver1.61.63.6-1.21.91.30.51.71.51.51.11.60.81.21.40.90.1
Mn content in liver0.40.41.30.30.30.80.10.40.30.3-0.3-0.10.61.10.61.01.2
Na content in liver0.50.62.61.1-0.0-0.21.60.70.60.60.10.41.20.40.90.1-0.3
Rb content in liver1.21.44.90.10.81.8-0.60.40.40.4-0.9-0.10.81.90.91.92.2
Se content in liver0.50.51.60.1-0.30.4-1.1-0.6-0.8-0.8-1.3-0.8-0.40.5-0.40.41.3
Sr content in liver1.81.63.0-0.5-1.0-1.3-1.0-1.3-1.4-1.4-0.2-1.1-1.6-1.5-1.6-1.7-1.0
Zn content in liver0.20.21.1-0.70.00.0-1.1-0.4-0.4-0.4-0.10.0-0.8-0.3-0.6-0.20.0
Bone: minimum diameter2.64.811.41.90.80.73.02.82.62.61.22.43.41.72.91.5-0.2
Time in familiar zone, hab. session 11.41.32.41.0-1.6-1.2-0.4-1.3-1.6-1.6-1.0-1.4-0.8-1.0-1.2-1.2-0.2
Time in novel zone, hab. session 10.70.71.30.50.60.51.10.91.01.00.00.71.10.71.10.80.1
Total zone transitions, hab. session 11.31.93.3-1.11.81.60.31.61.71.71.01.51.01.31.41.50.6
Total locomotion distance, hab. session 10.71.03.5-1.91.71.2-0.61.01.01.00.81.0-0.10.60.50.70.1
Locomotion velocity, hab. session 11.11.66.7-2.62.01.4-1.11.01.21.21.31.2-0.40.60.40.80.1
Time in familiar zone, hab. session 26.26.512.52.3-3.5-3.20.2-2.9-2.8-2.8-1.8-2.6-1.7-3.1-2.5-2.9-1.5
Time in novel zone, hab. session 24.14.16.6-0.92.62.20.82.52.42.41.02.11.92.52.42.30.9
Total zone transitions, hab. session 20.81.02.8-1.41.30.8-0.11.21.31.31.71.30.30.30.70.5-0.4
Total locomotion distance, hab. session 21.11.43.5-1.91.71.5-1.11.01.11.11.31.30.00.90.61.10.6
Locomotion velocity, hab. session 21.21.65.1-2.31.81.6-1.21.01.21.21.51.4-0.20.80.51.00.5
Novel to familiar place preference ratio0.91.02.2-0.71.20.51.31.21.41.41.01.50.60.21.00.3-0.7
Novelty place preference0.80.92.2-0.61.00.11.51.11.21.20.91.40.5-0.10.8-0.0-1.1
Time in novel zone, NPP test0.90.93.3-0.20.8-0.11.81.11.21.20.81.30.7-0.20.8-0.1-1.2
Total zone transitions, NPP test1.01.54.9-2.21.71.0-0.51.31.31.31.91.6-0.10.30.50.5-0.4
Total locomotion distance, NPP test0.81.05.3-2.31.50.6-0.70.70.90.91.31.1-0.7-0.2-0.0-0.1-0.8
Locomotion velocity, NPP test0.91.37.3-2.71.60.7-1.10.70.80.81.51.1-1.0-0.2-0.2-0.0-0.7
Intraocular pressure0.30.51.4-0.90.0-0.1-0.8-0.7-0.6-0.6-0.7-0.8-1.2-0.5-0.9-0.4-0.1
Delta distance traveled before/after self-admin2.12.33.91.0-2.0-1.6-0.6-1.8-1.8-1.8-1.3-1.8-1.4-1.3-1.8-1.4-0.3
Delta ambulatory time before/after self-admin2.32.85.11.1-2.2-2.1-0.4-2.0-2.0-2.0-1.0-1.9-1.5-1.6-1.9-1.7-0.8
Parametrial fat weight0.10.10.90.30.1-0.01.00.30.40.4-0.40.20.3-0.00.30.2-0.3
Pavlov. Cond. lever latency0.30.41.60.7-0.6-0.50.3-0.5-0.8-0.8-1.2-1.2-0.2-0.2-0.4-0.30.2
Pavlov. Cond. magazine entry latency0.10.10.40.6-0.5-0.2-0.2-0.4-0.3-0.3-0.7-0.20.1-0.1-0.1-0.20.1
Pavlov. Cond. change in total contacts0.70.84.2-1.50.51.0-2.1-0.6-0.3-0.30.0-0.0-0.90.3-0.60.51.1
Pavlov. Cond. index score0.00.10.20.0-0.3-0.2-0.5-0.4-0.2-0.20.00.2-0.2-0.2-0.2-0.3-0.1
Pavlov. Cond. latency score0.10.10.4-0.1-0.2-0.1-0.6-0.4-0.2-0.2-0.00.3-0.2-0.2-0.3-0.2-0.1
Pavlov. Cond. lever contacts0.40.51.6-1.10.80.5-0.30.50.80.81.21.20.00.20.30.2-0.3
Pavlov. Cond. magazine entry number0.10.21.0-1.00.70.5-0.40.2-0.0-0.00.2-0.1-0.40.4-0.00.30.3
Pavlov. Cond. intertrial magazine entries1.31.66.9-2.62.21.7-0.71.00.90.91.01.0-0.51.00.51.00.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.0-0.3-0.1-0.7-0.5-0.3-0.3-0.10.2-0.3-0.2-0.3-0.20.0
Pavlov. Cond. response bias0.10.20.9-0.20.1-0.1-0.00.30.50.50.90.70.2-0.30.1-0.2-0.6
Pavlov. Cond. lever latency1.41.82.81.0-1.7-1.60.1-1.5-1.5-1.5-1.4-1.5-1.1-1.5-1.4-1.5-0.7
Pavlov. Cond. magazine entry latency0.60.72.11.4-0.8-1.21.40.30.30.30.30.40.9-0.60.4-0.7-1.3
Pavlov. Cond. change in total contacts0.91.42.2-0.41.31.10.31.51.41.41.41.41.31.41.41.10.4
Pavlov. Cond. index score0.81.12.10.10.80.50.91.41.41.41.21.41.30.81.30.7-0.3
Pavlov. Cond. latency score0.81.12.00.20.80.51.01.41.41.41.11.41.40.81.40.7-0.3
Pavlov. Cond. lever contacts1.01.42.0-0.91.41.3-0.21.31.31.31.31.40.91.31.21.20.6
Pavlov. Cond. magazine entry number0.20.31.0-1.00.50.6-0.7-0.3-0.3-0.3-0.3-0.3-0.80.2-0.40.30.7
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.90.50.3-0.5-0.2-0.4-0.4-0.30.0-0.70.1-0.3-0.10.2
Pavlov. Cond. lever-magazine prob. diff.0.60.81.40.00.70.50.61.21.11.11.01.21.10.81.10.6-0.1
Pavlov. Cond. response bias0.81.12.1-0.31.00.90.31.41.31.31.51.31.21.01.20.90.1
Time in closed arm before self-admin0.50.62.10.8-1.1-1.30.6-0.2-0.2-0.21.4-0.10.2-0.5-0.2-0.8-1.3
Time in closed arm after self-admin0.20.21.0-0.5-0.0-0.50.3-0.3-0.3-0.31.00.2-0.4-0.2-0.2-0.7-0.9
Time in open arm before self-admin1.01.12.8-0.01.01.3-0.00.70.70.7-1.01.00.91.71.11.31.5
Time in open arm after self-admin0.10.10.60.7-0.2-0.30.80.20.20.2-0.5-0.20.4-0.20.1-0.1-0.4
Bone: periosteal estimation1.53.18.12.30.00.12.72.11.91.90.61.92.81.02.21.1-0.3
Bone: periosteal perimeter1.11.96.62.6-0.8-0.82.51.21.11.10.31.02.10.01.30.1-0.9
Bone: post-yield work1.52.23.6-0.81.61.60.61.71.91.91.41.61.31.51.51.70.7
Progressive ratio test 1 active lever presses0.00.10.4-0.00.2-0.10.40.20.20.2-0.60.00.0-0.10.10.0-0.2
Progressive ratio test 1 breakpoint0.00.00.4-0.00.2-0.20.30.10.10.1-0.6-0.0-0.1-0.2-0.0-0.1-0.3
Progressive ratio test 1 inactive lever presses0.81.12.4-1.41.61.4-1.01.01.01.0-0.10.90.11.20.61.21.0
Progressive ratio test 2 active lever presses1.11.32.60.40.91.3-0.21.11.11.1-1.0-0.01.21.51.21.61.6
Progressive ratio test 2 breakpoint1.21.32.70.50.91.3-0.21.11.11.1-1.0-0.01.31.61.21.71.6
Progressive ratio test 2 inactive lever presses0.00.10.5-0.00.10.1-0.40.20.20.2-0.7-0.4-0.10.1-0.10.30.3
Incentive Sensitization - Responses1.82.54.80.51.41.90.11.81.81.8-0.60.32.02.21.92.21.8
Incentive Sensitization - Breakpoint1.82.44.50.51.41.80.11.71.71.7-0.60.41.92.11.82.11.7
Sum of active levers in priming session hrs 5-61.31.24.6-1.71.21.4-2.10.40.40.40.30.3-0.50.90.11.11.6
Progressive ratio0.30.52.00.70.00.8-0.3-0.1-0.1-0.1-0.90.10.81.30.70.81.4
Food seeking constrained by brief footshock0.30.41.2-0.1-0.3-0.90.6-0.2-0.2-0.2-0.0-1.0-0.6-0.9-0.6-0.8-1.1
Seeking ratio, punishment vs. effort0.30.51.7-0.90.2-0.70.30.20.20.20.7-0.2-0.9-1.1-0.6-0.6-1.3
Retroperitoneal fat weight0.73.18.21.30.62.0-0.31.11.31.3-0.80.42.22.91.82.82.9
Reaction time number correct1.93.66.72.3-2.6-2.50.7-1.7-2.0-2.0-2.0-1.9-0.7-2.1-1.5-1.9-1.3
Reaction time mean minus median1.23.15.5-1.32.02.2-0.71.81.71.71.91.91.42.31.71.91.3
Reaction time mean minus median AUC2.46.09.3-2.13.03.0-1.12.62.52.52.42.71.83.12.42.61.5
Reaction time num false alarms1.11.67.22.7-0.6-0.42.40.90.70.7-1.1-0.11.90.31.20.60.1
Reaction time num false alarms AUC0.91.47.02.6-0.7-0.52.30.80.60.6-0.9-0.01.80.21.10.3-0.1
Reaction time trials correct on left1.93.66.72.3-2.6-2.50.7-1.7-2.0-2.0-2.0-1.9-0.7-2.1-1.5-1.9-1.3
Reaction time trials on left1.83.36.32.3-2.5-2.40.7-1.7-1.9-1.9-1.9-1.8-0.7-2.0-1.4-1.8-1.2
Reaction time mean1.52.34.1-1.31.81.8-0.31.51.51.51.92.01.11.81.51.50.9
Reaction time mean AUC2.33.66.1-1.72.32.2-0.32.02.02.02.32.51.32.11.81.90.9
Median of all reaction times1.01.52.9-1.21.51.4-0.01.21.31.31.61.70.81.31.11.20.5
Reaction time omissions3.55.19.6-1.62.93.1-0.12.32.22.21.52.41.82.82.42.62.0
Reaction time false alarm rate1.21.74.11.30.50.91.61.51.51.5-0.00.72.01.31.71.40.8
Reaction time premature initiation rate0.50.61.71.1-1.3-1.20.6-0.7-0.6-0.60.6-0.20.1-1.0-0.4-0.9-0.8
Reaction time premature initiations1.42.56.02.2-2.4-2.30.9-1.4-1.5-1.5-0.5-1.0-0.2-1.9-1.0-1.8-1.4
Std. dev. reaction times2.13.88.4-1.22.11.80.32.12.12.12.82.91.82.02.11.60.4
Reaction time trials completed1.83.36.32.3-2.5-2.40.7-1.7-1.9-1.9-1.9-1.8-0.7-2.0-1.4-1.8-1.2
Reaction time trials AUC1.73.25.72.2-2.4-2.40.7-1.6-1.9-1.9-2.0-1.7-0.7-1.9-1.3-1.7-1.1
Run reversals in cocaine runway, females0.40.43.0-1.70.90.4-0.60.20.20.20.3-0.5-1.0-0.1-0.50.0-0.3
Run reversals in cocaine runway, males0.10.10.5-0.5-0.0-0.0-0.6-0.1-0.1-0.1-0.3-0.7-0.7-0.2-0.5-0.10.1
Latency to leave start box in cocaine runway0.50.63.3-0.10.00.9-1.4-0.4-0.4-0.4-0.60.1-0.10.8-0.00.81.8
Latency to leave start box in cocaine runway, F0.50.62.50.9-0.50.4-0.6-0.5-0.5-0.5-1.5-0.50.00.3-0.20.61.6
Latency to leave start box in cocaine runway, M0.80.71.9-1.20.81.1-1.40.30.30.31.20.6-0.01.10.30.81.0
Std. dev. time between licks in bursts4.96.79.9-1.02.92.90.83.23.03.02.22.72.53.13.03.01.6
Total sessions with >9 infusions0.40.51.0-0.61.00.70.00.70.70.7-0.61.00.30.90.70.80.6
Short access day 1 total inactive lever presses0.10.10.7-0.30.40.10.10.50.50.5-0.80.1-0.10.2-0.00.40.1
Short access day 10 total inactive lever presses0.51.33.0-0.21.01.5-0.51.21.21.20.10.71.01.51.11.71.6
Short access day 1 total infusions0.20.30.9-1.00.50.1-0.8-0.3-0.3-0.3-0.80.4-0.80.2-0.4-0.00.2
Short access day 10 total infusions0.20.20.7-0.40.5-0.10.80.30.30.30.30.90.10.20.3-0.2-0.8
Short access total infusions0.20.31.2-0.60.70.30.30.50.50.50.21.10.20.60.50.2-0.2
Short access day 1 locomotion0.10.10.60.8-0.4-0.40.5-0.1-0.1-0.1-0.50.60.3-0.10.2-0.00.0
Short access day 10 total locomotion0.71.32.50.6-1.3-1.1-0.8-1.4-1.4-1.4-1.6-1.4-1.1-1.1-1.3-0.80.2
Short access total locomotion0.10.20.70.6-0.5-0.60.4-0.3-0.3-0.3-0.9-0.1-0.1-0.1-0.2-0.3-0.2
One hour access (0.3 mA shock)0.20.21.30.20.20.4-0.30.20.20.2-1.1-0.60.10.50.10.60.8
Compulsive drug intake0.91.13.01.30.30.51.71.21.21.20.30.11.70.71.40.90.1
One hour access (shock baseline)0.20.41.9-0.80.20.2-1.4-0.4-0.4-0.4-0.9-0.2-0.80.1-0.50.10.6
Social response proportion0.40.42.0-0.20.2-0.61.10.30.50.50.60.2-0.1-1.0-0.0-0.4-1.4
Social responses0.40.62.11.5-0.8-0.81.40.20.30.30.0-0.10.8-0.80.3-0.4-0.9
Social time0.10.10.90.0-0.10.10.0-0.10.10.1-0.4-0.9-0.2-0.2-0.30.10.1
Soleus weight0.61.73.61.5-1.6-1.91.4-1.0-1.0-1.0-1.0-0.9-0.5-1.7-0.9-1.7-1.5
Bone: stiffness0.30.52.20.7-0.1-0.61.50.70.60.60.20.40.8-0.10.5-0.5-1.1
Tibialis anterior weight0.20.61.00.7-1.0-0.6-0.3-0.8-0.9-0.9-1.0-1.0-0.6-0.8-0.8-0.40.1
Time to tail flick, vehicle, before self-admin0.40.41.31.1-0.30.40.10.20.20.2-0.60.50.90.70.70.71.1
Time to tail flick, vehicle, after self-admin1.62.24.1-1.12.02.0-0.21.61.61.6-0.80.80.71.81.32.01.7
Time to tail flick, test, before self-admin1.11.12.7-0.61.11.3-0.71.21.11.10.10.60.71.20.91.61.5
Time to tail flick, test, after self-admin0.20.20.9-0.2-0.2-0.4-0.3-0.4-0.4-0.4-0.4-1.0-0.7-0.4-0.6-0.3-0.0
Delta time to tail flick, vehicle, before/after SA0.40.42.0-1.41.10.5-0.20.40.40.4-0.5-0.4-0.80.1-0.30.2-0.1
Delta time to tail flick, test, before/after SA0.70.71.50.4-0.8-0.7-0.2-1.1-1.1-1.1-1.2-1.2-0.9-0.4-0.9-0.9-0.2
Tibia length0.10.20.9-0.90.6-0.10.40.30.30.30.20.3-0.6-0.6-0.2-0.5-0.9
Ambulatory time before self-admin0.10.21.4-0.90.40.2-1.20.1-0.0-0.00.3-0.1-0.30.4-0.10.20.3
Ambulatory time after self-admin2.42.84.70.4-2.0-2.0-1.6-2.1-2.2-2.2-0.4-1.6-1.8-1.2-2.1-1.7-0.7
Bone: tissue strength0.10.10.5-0.70.3-0.10.10.10.00.0-0.10.0-0.6-0.5-0.3-0.3-0.5
Total heroin consumption0.30.32.10.2-0.1-0.60.50.40.40.41.40.30.4-0.20.2-0.3-1.0
Bone: trabecular number3.55.830.45.5-3.8-2.92.8-1.3-1.3-1.3-2.3-1.01.5-1.5-0.1-1.5-1.0
Bone: trabecular spacing2.12.817.9-4.22.51.2-1.70.80.80.82.40.9-1.50.4-0.3-0.0-0.6
Bone: trabecular thickness6.07.522.04.7-4.2-3.51.6-2.5-2.6-2.6-3.1-2.3-0.2-2.5-1.6-2.5-1.2
Bone: trabecular tissue density0.40.62.0-1.40.60.3-1.2-0.5-0.6-0.6-0.7-0.5-1.3-0.2-0.8-0.30.1
Water consumed over 24 hours0.50.63.51.9-1.4-0.80.4-0.6-0.6-0.6-0.9-0.50.5-0.5-0.1-0.20.1
Number of responses in last shaping day0.40.51.70.1-0.5-0.2-1.1-0.8-0.8-0.8-1.3-0.7-0.6-0.0-0.7-0.10.6