Hub : Genes

Mettl7a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Mettl7a 0.24 0.16 1.2e-11 0.17 0.18 0.17 0.17 2.5e-09 9.7e-10 2.4e-09 2.1e-09
2 IC gene expression Mettl7a 0.81 0.09 0.0e+00 0.58 0.6 0.62 0.62 1.5e-29 8.2e-31 1.4e-32 2.7e-32
3 pVTA gene expression Mettl7a 0.74 0.1 0.0e+00 0.7 0.72 0.72 0.72 1.4e-78 8.3e-83 2.8e-81 1.2e-81
4 LHb alternative polyA XM_039079337.2 0.14 0.11 8.2e-03 0.11 0.03 0.05 0.07 1.6e-03 7.0e-02 2.7e-02 9.8e-03
5 RMTg gene expression Mettl7a 0.27 0.15 1.5e-06 0.25 0.07 0.25 0.14 3.0e-07 5.6e-03 3.2e-07 1.3e-04
6 OFC gene expression Mettl7a 0.6 0.16 8.4e-13 0.41 0.4 0.38 0.38 1.0e-10 1.8e-10 6.0e-10 5.7e-10
7 IC mRNA stability Mettl7a 0.09 0.07 1.9e-03 0.07 0.05 0.05 0.05 7.0e-04 4.7e-03 4.9e-03 2.6e-03
8 PL gene expression Mettl7a 0.5 0.13 0.0e+00 0.66 0.66 0.66 0.66 3.3e-96 2.9e-96 1.6e-96 2.3e-96
9 pVTA mRNA stability Mettl7a 0.11 0.09 1.9e-08 0.11 0.1 0.11 0.1 6.8e-09 1.7e-08 7.7e-09 1.5e-08
10 Brain gene expression Mettl7a 0.82 0.05 0.0e+00 0.76 0.78 0.79 0.78 9.8e-107 6.9e-115 5.3e-116 1.9e-113
11 Brain mRNA stability Mettl7a 0.34 0.15 0.0e+00 0.35 0.35 0.34 0.35 4.1e-34 2.6e-33 7.2e-33 4.0e-34
12 NAcc gene expression Mettl7a 0.58 0.11 0.0e+00 0.7 0.7 0.71 0.71 1.2e-151 9.6e-151 1.2e-154 5.8e-155
13 BLA gene expression Mettl7a 0.68 0.1 0.0e+00 0.65 0.69 0.69 0.68 1.5e-44 1.7e-49 4.7e-49 1.5e-48
14 PL mRNA stability Mettl7a 0.1 0.06 3.9e-14 0.13 0.13 0.13 0.13 3.1e-14 2.3e-14 6.6e-14 2.6e-14
15 LHb gene expression Mettl7a 0.8 0.1 5.6e-17 0.44 0.4 0.45 0.28 1.2e-11 2.0e-10 4.1e-12 2.6e-07
16 Adipose gene expression Mettl7a 0.12 0.06 0.0e+00 0.15 0.15 0.14 0.15 3.1e-16 4.6e-16 8.8e-16 5.3e-16
17 NAcc mRNA stability Mettl7a 0.08 0.04 0.0e+00 0.11 0.12 0.11 0.11 3.5e-16 2.5e-17 3.3e-16 7.4e-17
18 Eye gene expression Mettl7a 0.37 0.17 5.8e-05 0.32 0.34 0.31 0.34 8.6e-06 3.3e-06 1.2e-05 3.4e-06
19 IL gene expression Mettl7a 0.63 0.22 1.2e-10 0.18 0.32 0.32 0.16 3.8e-05 1.9e-08 1.7e-08 1.3e-04
20 Adipose mRNA stability Mettl7a 0.12 0.06 0.0e+00 0.15 0.15 0.15 0.15 6.8e-16 1.6e-16 5.1e-16 6.5e-16
21 Brain alternative polyA XM_039079337.2 0.17 0.13 2.2e-06 0.07 0.06 0.04 0.06 8.6e-07 3.9e-06 6.7e-05 2.2e-06
22 Brain alternative polyA XM_039079338.2 0.16 0.13 4.8e-06 0.07 0.06 0.04 0.06 9.8e-07 6.5e-06 5.6e-05 1.9e-06
23 IL mRNA stability Mettl7a 0.29 0.17 2.8e-05 0.17 0.2 0.22 0.2 7.7e-05 1.7e-05 3.9e-06 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density5.69.713.33.33.23.03.13.13.03.23.13.03.02.93.13.13.02.83.13.03.43.12.83.3-3.33.6
Area under the delay curve1.01.12.61.01.21.10.40.41.10.91.11.11.11.21.11.11.01.10.71.01.01.21.01.6-1.60.6
BMI with tail6.422.029.34.64.84.85.45.44.65.34.75.04.74.74.64.74.84.75.44.74.44.44.64.1-4.13.0
BMI without tail1.85.67.92.42.52.42.82.82.32.72.32.62.42.42.22.32.42.32.82.32.32.02.21.8-1.82.3
Body weight6.729.434.75.45.75.75.75.75.55.75.55.95.75.55.55.35.45.35.75.35.55.25.04.7-4.74.6
Weight adjusted by age0.40.71.40.80.60.61.01.00.60.90.70.60.70.70.71.01.01.01.01.00.20.81.20.6-0.60.4
Bone surface8.014.616.83.93.93.84.04.03.74.13.93.73.73.73.83.73.73.54.03.74.13.83.53.8-3.83.8
Bone volume7.413.315.13.83.73.63.73.73.73.73.73.63.53.63.73.63.53.43.63.53.93.73.43.8-3.83.9
Breakpoint value in progressive ratio session0.60.71.10.80.81.01.01.01.00.80.90.90.90.90.80.80.70.91.00.70.90.80.70.5-0.50.8
Number of licking bursts0.91.43.2-1.1-1.1-0.9-1.7-1.7-0.8-1.8-1.0-0.7-0.8-0.8-0.9-1.0-1.1-0.9-1.7-1.0-1.2-1.0-0.9-1.31.3-1.3
Context. condit. distance diff. score0.50.71.70.70.80.91.11.10.81.20.80.90.80.70.70.60.60.81.10.60.80.60.50.4-0.41.3
Locomotion velocity, session 14.14.55.7-2.2-2.1-2.2-1.8-1.8-2.4-1.7-2.2-2.3-2.2-2.3-2.2-2.2-2.0-2.2-1.8-2.1-2.2-2.2-2.1-2.12.1-1.9
Locomotion distance, session 13.24.04.8-2.0-2.1-2.2-1.9-1.9-2.2-1.8-2.0-2.2-2.1-2.1-2.0-1.9-1.9-2.0-1.9-1.9-2.1-2.0-1.8-1.91.9-2.1
Locomotion velocity, session 20.50.61.0-0.7-0.7-0.8-0.7-0.7-1.0-0.6-0.8-0.8-0.7-0.9-0.7-0.7-0.7-1.0-0.7-0.7-0.6-0.8-0.7-0.60.6-0.6
Locomotion distance, session 23.75.26.0-2.3-2.4-2.4-2.5-2.5-2.4-2.4-2.2-2.4-2.3-2.4-2.2-2.2-2.2-2.3-2.4-2.2-2.2-2.3-2.1-2.02.0-2.2
Locomotion velocity, session 35.05.76.5-2.4-2.4-2.4-2.5-2.5-2.5-2.6-2.4-2.2-2.4-2.5-2.4-2.5-2.5-2.5-2.5-2.5-2.0-2.4-2.5-2.32.3-1.4
Locomotion distance, session 32.93.24.6-1.7-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.9-1.9-1.9-1.8-1.9-2.0-2.1-1.7-2.0-1.2-1.8-2.1-1.71.70.5
Stereotopy head waving bouts, day 30.20.22.8-0.1-0.2-0.1-0.4-0.4-0.0-0.5-0.10.00.00.1-0.00.10.20.2-0.30.2-0.50.10.40.1-0.1-1.7
Stereotopy head waving duration, day 30.20.31.9-0.5-0.4-0.3-0.8-0.8-0.3-0.9-0.4-0.2-0.3-0.2-0.3-0.3-0.3-0.2-0.8-0.3-0.4-0.2-0.2-0.10.1-1.4
Locomotion velocity, session 73.23.54.6-1.8-1.9-1.9-1.8-1.8-1.9-1.8-1.9-2.0-1.9-2.0-1.9-2.0-2.1-2.1-1.8-2.0-1.5-1.9-2.1-1.81.8-0.5
Locomotion distance, session 73.94.96.4-2.3-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.3-2.3-2.2-2.4-2.4-2.4-2.2-2.4-1.8-2.2-2.5-2.22.2-0.8
Stereotopy head waving bouts, day 71.01.12.01.11.00.91.11.11.01.11.01.01.11.10.91.21.21.31.11.20.31.01.41.0-1.0-0.0
Stereotopy head waving duration, day 71.11.32.11.11.11.01.11.11.11.01.11.11.21.21.11.31.31.41.11.30.61.11.51.2-1.2-0.0
Locomotion velocity, session 80.30.40.6-0.7-0.6-0.7-0.4-0.4-0.7-0.4-0.7-0.6-0.6-0.7-0.7-0.7-0.6-0.6-0.3-0.7-0.8-0.8-0.7-0.70.7-0.3
Locomotion distance, session 80.91.31.9-1.2-1.1-1.1-0.8-0.8-1.3-0.8-1.1-1.2-1.1-1.3-1.2-1.2-1.2-1.2-0.8-1.2-1.0-1.4-1.3-1.31.3-0.4
Degree of sensitization distance0.10.11.4-0.10.00.10.20.20.10.20.10.20.10.20.10.10.20.30.20.2-0.20.10.2-0.00.0-1.2
Degree of sensitization stereotypy1.11.21.81.11.00.91.31.31.11.41.00.91.11.10.91.21.21.31.31.20.40.91.31.0-1.00.4
Conditioned locomotion0.20.20.7-0.4-0.5-0.5-0.8-0.8-0.3-0.8-0.4-0.5-0.5-0.4-0.3-0.4-0.5-0.5-0.8-0.5-0.2-0.3-0.5-0.20.20.3
Cocaine response after cond. corrected0.00.10.4-0.2-0.2-0.2-0.3-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.1-0.1-0.2-0.2-0.1-0.3-0.20.0-0.00.0-0.7
Cocaine response after cond. not corrected0.30.30.4-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.5-0.6-0.6-0.5-0.6-0.6-0.5-0.50.5-0.6
Cocaine response before conditioning1.51.82.6-1.4-1.3-1.3-1.1-1.1-1.3-1.1-1.4-1.4-1.3-1.4-1.4-1.5-1.5-1.5-1.2-1.5-1.1-1.4-1.6-1.51.5-0.5
Saline control response0.00.10.2-0.1-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.0-0.1-0.3-0.1-0.3-0.3-0.3-0.3-0.30.2-0.1-0.4-0.30.30.4
Bone: connectivity density2.64.15.42.12.11.92.22.21.72.32.01.91.81.82.01.91.91.62.21.92.31.91.72.2-2.22.3
Bone: cortical apparent density0.50.74.6-0.7-0.9-1.0-0.7-0.7-1.0-0.6-0.8-1.0-1.0-0.8-0.8-0.5-0.4-0.6-0.7-0.4-1.1-0.6-0.2-0.30.3-2.1
Bone: cortical area6.39.611.33.13.23.23.03.03.43.03.23.33.23.23.13.03.03.13.02.93.23.12.83.0-3.03.3
Bone: cortical porosity0.10.11.30.30.20.30.20.20.30.30.30.10.20.10.30.20.10.10.20.10.70.3-0.00.0-0.01.2
Bone: cortical porosity0.10.11.10.1-0.00.0-0.0-0.00.10.00.0-0.2-0.2-0.10.1-0.1-0.2-0.2-0.1-0.10.50.0-0.3-0.10.11.0
Bone: cortical thickness2.13.54.51.82.02.01.91.92.11.91.92.12.02.01.81.81.82.01.81.81.81.81.71.8-1.81.8
Bone: cortical thickness0.20.20.5-0.4-0.3-0.3-0.4-0.4-0.4-0.3-0.4-0.3-0.3-0.5-0.5-0.6-0.6-0.6-0.4-0.6-0.2-0.6-0.7-0.60.60.7
Bone: cortical tissue density0.60.94.9-0.8-1.0-1.1-0.8-0.8-1.1-0.7-0.9-1.1-1.1-0.9-0.9-0.6-0.5-0.7-0.8-0.5-1.2-0.7-0.3-0.40.4-2.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.1-0.1-0.00.40.4-0.30.4-0.1-0.1-0.1-0.2-0.2-0.1-0.0-0.00.6-0.0-0.3-0.2-0.1-0.40.4-0.3
Condit. Reinf. active-inactive response ratio0.20.20.70.50.40.50.70.70.30.60.50.40.30.30.40.40.40.40.90.40.60.50.30.3-0.30.6
Condit. Reinf. active responses0.50.61.2-0.8-0.7-0.7-0.3-0.3-1.0-0.3-0.8-0.7-0.7-0.9-0.8-0.7-0.6-0.7-0.1-0.7-1.0-0.9-0.6-1.01.0-1.1
Condit. Reinf. inactive responses2.63.15.0-1.9-1.8-1.8-1.7-1.7-1.9-1.7-1.8-1.7-1.7-1.7-1.8-1.7-1.6-1.6-1.7-1.6-2.1-1.8-1.5-1.81.8-2.2
Incentive salience index mean0.20.21.00.30.30.40.80.80.10.80.30.30.40.20.20.30.40.41.00.4-0.00.20.4-0.00.0-0.1
Condit. Reinf. lever presses0.60.91.70.90.91.01.21.20.71.20.90.91.00.80.81.01.11.01.31.10.40.81.20.6-0.6-0.0
Condit. Reinf. active minus inactive responses1.11.41.81.11.21.11.31.31.11.31.11.21.11.21.21.21.21.31.31.21.01.21.21.2-1.20.5
Condit. Reinf. active-inactive response ratio0.80.91.20.91.01.01.01.00.91.00.91.11.01.00.90.91.01.01.00.90.91.00.91.1-1.10.4
Condit. Reinf. active responses0.20.20.50.40.40.40.60.60.40.70.40.50.40.40.40.50.50.60.70.50.30.50.50.4-0.40.3
Condit. Reinf. inactive responses0.50.61.1-0.8-0.9-0.9-0.4-0.4-0.8-0.5-0.8-0.9-0.8-0.9-0.9-0.8-0.8-0.7-0.4-0.7-1.0-0.9-0.7-1.01.0-0.4
Condit. Reinf. lever presses0.00.00.2-0.10.00.1-0.3-0.30.1-0.30.00.20.10.10.1-0.1-0.2-0.0-0.3-0.20.30.1-0.3-0.00.00.4
Condit. Reinf. lever reinforcers received0.00.00.10.00.10.10.30.30.10.30.10.20.10.10.10.10.10.20.30.1-0.00.10.1-0.00.00.1
Conditioned reinforcement - actives0.61.11.8-0.9-1.0-1.1-1.2-1.2-1.1-1.2-1.0-1.0-1.1-1.0-1.0-1.0-1.1-1.2-1.0-1.0-0.7-1.0-1.0-0.80.8-1.3
Conditioned reinforcement - inactives3.75.46.6-2.3-2.3-2.3-2.6-2.6-2.4-2.4-2.4-2.2-2.3-2.4-2.3-2.4-2.4-2.5-2.4-2.4-2.1-2.3-2.4-2.32.3-1.3
Conditioned locomotion0.30.42.2-0.6-0.5-0.5-0.7-0.7-0.6-0.9-0.5-0.5-0.6-0.4-0.6-0.7-0.7-0.7-0.6-0.7-0.3-0.4-0.70.0-0.0-1.5
Patch foraging indifference point 0 sec4.38.09.5-2.9-2.9-2.8-2.4-2.4-2.9-2.5-2.9-3.0-2.9-3.0-3.0-3.0-3.0-3.0-2.3-3.0-2.8-3.0-3.1-3.13.1-1.6
Patch foraging indifference point AUC0.60.91.7-1.0-0.9-1.1-1.1-1.1-0.9-0.8-1.0-0.9-0.9-0.9-1.0-0.9-0.8-0.7-0.9-0.8-1.3-0.8-0.7-0.70.7-1.3
Delay disc. indifference point, 0s delay1.71.82.21.51.41.50.80.81.51.21.41.41.51.41.51.41.41.41.11.41.51.41.41.3-1.31.4
Delay disc. indifference point, 16s delay0.70.71.70.91.00.90.50.50.80.80.90.90.80.90.80.80.80.80.60.80.91.00.81.3-1.30.6
Delay disc. indifference point, 2s delay2.02.23.51.51.51.41.11.11.51.41.41.41.51.61.51.71.71.81.31.70.81.61.91.8-1.80.5
Delay disc. indifference point, 24s delay0.50.51.20.60.80.80.40.40.80.70.70.70.70.80.70.70.70.80.50.70.60.90.71.1-1.10.3
Delay disc. indifference point, 4s delay1.31.42.91.21.31.20.80.81.21.01.11.11.21.31.21.21.21.20.91.21.11.31.21.7-1.71.0
Delay disc. indifference point, 8s delay0.91.01.81.01.21.20.40.41.10.91.11.11.11.11.11.00.90.90.70.91.31.10.81.3-1.30.9
Indifference point function ln k3.46.06.92.52.52.52.62.62.42.42.52.32.32.42.52.52.52.32.62.52.62.52.32.5-2.52.0
Indifference point function log k3.46.06.92.52.52.52.62.62.42.42.52.32.32.42.52.52.52.32.62.52.62.52.32.5-2.52.0
Patch foraging total patch changes 0 sec4.07.59.3-2.8-2.8-2.7-2.4-2.4-2.8-2.5-2.8-2.9-2.8-2.9-2.9-3.0-3.0-2.9-2.2-3.0-2.6-2.9-3.1-2.92.9-1.4
Patch foraging total patch changes 12 sec5.57.18.0-2.8-2.7-2.7-2.4-2.4-2.7-2.2-2.8-2.7-2.7-2.8-2.8-2.7-2.7-2.6-2.3-2.7-2.8-2.8-2.7-2.72.7-2.6
Patch foraging total patch changes 18 sec5.27.98.8-2.9-2.9-3.0-2.7-2.7-2.8-2.5-3.0-2.9-2.9-2.9-2.9-2.9-3.0-2.8-2.7-3.0-2.9-2.9-2.9-2.82.8-1.9
Patch foraging total patch changes 24 sec2.64.55.5-2.2-2.2-2.1-2.0-2.0-2.0-1.9-2.2-2.2-2.1-2.2-2.2-2.2-2.3-2.0-1.9-2.3-2.2-2.2-2.2-2.32.3-0.9
Patch foraging total patch changes 6 sec5.88.89.9-3.1-3.1-3.0-2.7-2.7-3.0-2.7-3.1-3.1-3.0-3.1-3.1-3.1-3.1-2.9-2.7-3.1-3.1-3.1-3.0-3.13.1-2.0
Patch foraging time to switch 0 sec1.73.54.4-1.8-1.9-2.0-1.7-1.7-2.0-1.5-2.0-1.7-1.9-1.9-2.0-1.8-1.9-1.9-1.8-1.8-2.1-2.0-1.8-2.12.1-1.5
Patch foraging water rate 0 sec3.16.47.62.52.62.72.52.52.72.32.62.52.72.62.62.42.52.62.62.42.72.62.32.5-2.52.2
Patch foraging water rate 12 sec1.73.54.61.91.91.91.81.81.81.82.01.61.81.82.01.91.81.71.91.82.11.91.71.9-1.92.1
Patch foraging water rate 18 sec0.30.40.80.70.60.50.50.50.60.40.70.30.50.60.70.70.70.70.60.70.80.80.70.9-0.90.7
Patch foraging water rate 24 sec3.95.56.22.42.32.32.22.22.42.12.52.12.32.32.42.42.42.32.32.42.52.52.42.4-2.42.0
Patch foraging water rate 6 sec6.08.810.03.03.13.12.82.83.12.83.12.83.13.03.12.92.92.93.02.93.23.12.83.0-3.02.7
Seeking ratio, delayed vs. immediate footshock0.40.40.90.70.60.60.60.60.71.00.80.70.70.70.70.70.80.80.70.80.70.50.70.3-0.30.1
Distance traveled before self-admin1.72.32.7-1.7-1.6-1.6-1.3-1.3-1.6-1.5-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.4-1.6-1.6-1.5-1.6-1.31.3-1.0
Distance traveled after self-admin1.21.52.6-1.3-1.1-1.3-0.8-0.8-1.2-1.0-1.3-1.2-1.2-1.3-1.3-1.5-1.4-1.4-1.2-1.5-0.8-1.3-1.6-1.21.2-0.0
Extensor digitorum longus weight5.320.626.34.64.54.44.84.84.74.94.54.64.64.74.44.84.95.14.84.93.34.55.14.2-4.21.9
Bone: elastic displacement7.48.59.4-3.0-3.0-3.0-2.9-2.9-3.0-2.9-3.0-3.1-3.1-3.0-3.0-3.0-3.0-3.0-3.0-3.0-2.5-3.0-3.0-2.72.7-2.1
Bone: elastic work0.20.30.5-0.5-0.5-0.5-0.7-0.7-0.5-0.7-0.4-0.5-0.6-0.5-0.4-0.6-0.6-0.6-0.7-0.60.1-0.4-0.7-0.20.2-0.3
Bone: endosteal estimation6.213.717.93.93.83.83.53.53.83.53.83.73.73.73.83.63.53.43.53.64.13.73.33.7-3.74.2
Bone: endosteal perimeter6.213.116.23.83.73.73.33.33.93.33.73.73.73.83.73.63.53.53.33.53.93.63.43.6-3.64.0
Epididymis fat weight0.30.94.30.71.01.10.90.90.90.90.91.11.00.80.90.50.50.50.90.41.60.70.10.3-0.32.1
Delta time in closed arm before/after self-admin0.00.00.10.20.20.30.30.30.20.20.20.20.20.20.20.10.10.20.30.10.30.10.0-0.10.1-0.4
Delta time in open arm before/after self-admin1.31.22.2-1.2-1.0-1.2-0.8-0.8-1.2-1.1-1.2-1.2-1.2-1.2-1.2-1.3-1.3-1.4-1.0-1.4-0.7-1.1-1.5-0.80.80.3
Diff in mean of infusions in LGA sessions1.01.22.31.01.11.11.51.51.01.31.01.11.11.11.01.11.11.21.21.10.71.01.11.0-1.00.2
Delay discount exponential model param1.01.22.8-1.0-1.2-1.1-0.5-0.5-1.1-0.9-1.0-1.0-1.1-1.2-1.1-1.1-1.0-1.1-0.7-1.1-0.9-1.3-1.1-1.71.7-0.6
Extinction: sum of active levers before priming2.62.94.01.71.61.82.02.01.82.01.81.91.81.81.71.81.92.01.71.81.41.51.80.8-0.80.5
Active lever presses in extinction session 60.10.11.40.20.40.50.20.20.40.10.30.50.40.30.40.20.10.30.20.10.50.30.00.1-0.11.2
Bone: final force10.717.120.14.24.34.34.24.24.14.34.24.24.24.14.24.04.03.94.14.04.54.23.74.2-4.23.8
Bone: final moment11.818.923.14.44.54.54.34.34.34.44.54.44.44.34.44.24.24.04.24.24.84.43.94.5-4.54.1
Food consumed during 24 hour testing period1.72.33.21.41.61.61.81.81.41.81.61.61.51.41.51.41.41.41.71.41.81.51.21.4-1.41.2
Glucose0.20.30.5-0.7-0.5-0.5-0.4-0.4-0.6-0.3-0.7-0.5-0.4-0.6-0.7-0.7-0.6-0.6-0.5-0.7-0.7-0.6-0.7-0.70.7-0.2
Heart weight0.30.41.70.70.70.70.70.70.60.80.60.70.60.50.70.50.40.50.70.41.00.60.30.3-0.31.3
Delay discount hyperbolic model param1.01.12.7-1.0-1.2-1.1-0.5-0.5-1.1-0.9-1.0-1.0-1.1-1.2-1.1-1.1-1.1-1.1-0.7-1.1-0.9-1.3-1.1-1.61.6-0.6
Intermittent access intake day 1-15 change0.10.22.40.30.40.40.10.10.20.30.30.40.30.20.30.20.20.00.40.10.80.2-0.00.1-0.11.6
Intermittent access intake escalation0.30.63.10.80.80.80.50.50.60.70.70.80.70.60.80.60.60.50.80.61.10.60.50.4-0.41.8
Intermittent access intake escalation 20.10.21.80.30.30.30.30.30.30.40.30.40.30.20.30.20.20.10.30.20.60.20.1-0.10.11.3
Intermitt. access day 1 inactive lever presses0.10.22.0-0.4-0.4-0.5-0.4-0.4-0.5-0.5-0.4-0.3-0.5-0.3-0.4-0.3-0.3-0.4-0.4-0.3-0.4-0.3-0.20.1-0.1-1.4
Intermitt. access day 15 inactive lever presses0.00.10.5-0.0-0.2-0.2-0.1-0.1-0.2-0.5-0.0-0.2-0.2-0.3-0.0-0.1-0.1-0.3-0.5-0.10.2-0.1-0.1-0.10.10.7
Intermitt. access escalation Index0.10.11.30.2-0.0-0.10.10.1-0.10.10.10.00.10.10.00.30.40.30.10.4-0.40.00.60.1-0.1-1.1
Intermittent access day 1 total infusions1.21.93.0-1.4-1.3-1.4-1.6-1.6-1.4-1.6-1.3-1.4-1.4-1.3-1.3-1.4-1.5-1.5-1.6-1.4-1.1-1.2-1.5-0.60.6-1.7
Intermittent access day 15 total infusions0.40.61.0-0.8-0.7-0.7-1.0-1.0-0.8-0.9-0.8-0.7-0.8-0.8-0.7-0.9-0.9-1.0-0.9-0.9-0.4-0.7-1.0-0.50.5-0.5
Intermittent access terminal intake (last 3 days)0.60.81.3-0.9-0.8-0.8-1.2-1.2-0.9-1.0-0.9-0.8-0.9-0.9-0.8-1.0-1.0-1.1-1.0-1.0-0.6-0.8-1.1-0.60.6-0.6
Intermittent access total infusions1.11.32.0-1.2-1.0-1.1-1.4-1.4-1.1-1.3-1.1-1.1-1.1-1.1-1.1-1.2-1.3-1.3-1.3-1.3-0.9-1.0-1.3-0.80.8-1.1
Intermittent access day 1 locomotion1.21.62.6-1.3-1.0-1.3-1.5-1.5-1.2-1.5-1.2-1.3-1.3-1.1-1.2-1.3-1.4-1.4-1.5-1.3-0.8-0.9-1.4-0.10.1-1.6
Intermittent access day 15 total locomotion0.40.71.5-0.7-0.4-0.6-1.2-1.2-0.7-1.0-0.7-0.7-0.7-0.7-0.7-1.0-1.0-1.2-0.9-1.1-0.1-0.5-1.20.1-0.10.5
Intermittent access total locomotion2.42.94.7-1.7-1.5-1.7-2.2-2.2-1.7-2.0-1.7-1.7-1.7-1.6-1.7-1.8-1.9-2.0-2.0-1.9-1.2-1.5-2.0-0.80.8-1.2
Intermittent access standard deviation0.10.30.7-0.4-0.3-0.4-0.3-0.3-0.5-0.5-0.3-0.4-0.4-0.5-0.4-0.6-0.6-0.8-0.5-0.60.2-0.5-0.8-0.40.40.8
Left kidney weight1.67.510.02.82.82.82.92.92.83.02.82.92.92.72.82.72.72.72.82.62.82.52.52.0-2.03.2
Right kidney weight4.520.324.74.64.64.64.94.94.65.04.54.84.74.54.54.54.54.54.74.44.44.24.33.7-3.74.4
Cocaine induced anxiety1.72.53.21.71.61.61.71.71.61.81.61.71.61.61.61.51.51.51.51.51.81.51.41.3-1.31.5
Post-drug Anxiety3.03.24.91.91.92.01.51.52.01.81.91.91.91.81.91.81.71.71.61.72.21.71.61.3-1.32.0
Baseline Anxiety0.30.30.60.60.50.80.00.00.60.30.60.50.60.60.60.70.70.60.60.70.60.60.70.3-0.30.1
Tail length0.00.22.50.20.30.4-0.1-0.10.3-0.20.20.50.40.30.30.0-0.1-0.0-0.1-0.10.50.1-0.2-0.10.11.6
Length with tail1.56.78.82.62.82.92.42.42.82.32.73.03.02.72.82.52.42.42.22.42.92.52.32.2-2.22.9
Length without tail5.417.320.34.24.44.54.14.14.34.04.34.54.54.34.44.14.14.14.04.04.34.23.94.0-4.03.3
Times rat made contact with spout0.00.00.20.10.20.20.40.40.20.40.10.30.30.20.10.00.10.20.30.00.20.1-0.0-0.00.00.3
Lifetime Intake1.92.43.5-1.6-1.4-1.4-1.9-1.9-1.5-1.7-1.5-1.5-1.5-1.5-1.5-1.7-1.7-1.8-1.7-1.7-1.1-1.4-1.8-0.90.9-1.4
Liver weight, left10.116.719.44.14.34.23.93.94.44.04.24.34.24.24.24.03.93.93.93.84.44.13.63.9-3.94.3
Liver weight, right2.95.07.52.32.32.42.22.22.52.22.42.22.32.22.42.22.12.22.12.12.72.21.91.8-1.82.7
Locomotor activity1.01.63.0-1.3-1.4-1.2-1.1-1.1-1.1-1.1-1.2-1.3-1.3-1.3-1.2-1.3-1.3-1.2-1.1-1.3-1.3-1.3-1.3-1.71.7-0.5
Locomotor testing distance2.54.46.5-2.2-2.2-2.1-1.8-1.8-2.1-1.8-2.1-2.2-2.2-2.2-2.1-2.2-2.2-2.1-1.9-2.2-2.1-2.3-2.2-2.62.6-1.3
Locomotor testing rearing1.42.84.4-1.6-1.7-1.6-1.1-1.1-1.7-1.1-1.7-1.9-1.8-1.9-1.8-1.8-1.8-1.9-1.0-1.8-1.5-1.9-1.9-2.12.1-0.4
Locomotion in novel chamber4.55.86.52.52.52.62.02.02.52.32.42.52.52.52.42.42.42.42.42.42.42.52.32.4-2.42.2
Locomotion in novel chamber post-restriction0.10.20.50.40.40.50.20.20.40.30.50.50.40.40.50.40.40.30.30.30.70.50.20.4-0.40.6
Fecal boli incidents, locomotor time 10.60.81.6-1.1-0.8-0.9-0.6-0.6-1.0-0.8-1.0-0.9-0.9-0.9-1.0-1.1-1.1-1.1-0.8-1.1-0.6-0.9-1.3-0.60.6-0.7
Change in fecal boli incidents, locomotor task0.00.00.20.10.00.1-0.2-0.20.2-0.10.20.10.10.20.20.30.20.4-0.10.3-0.10.30.40.2-0.2-0.3
Time >=10cm from walls, locomotor time 10.60.61.0-0.8-0.8-0.7-1.0-1.0-0.7-0.9-0.7-0.8-0.8-0.7-0.7-0.8-0.9-0.8-0.7-0.9-0.6-0.6-0.9-0.60.6-0.7
Bouts of movement, locomotor time 10.00.00.5-0.1-0.2-0.10.10.1-0.0-0.10.0-0.1-0.1-0.10.00.00.00.1-0.00.0-0.2-0.00.1-0.30.3-0.7
Total resting periods, locomotor time 10.60.61.3-0.8-0.9-0.8-0.6-0.6-0.7-0.8-0.7-0.8-0.8-0.8-0.7-0.7-0.7-0.6-0.7-0.7-0.8-0.7-0.6-1.01.0-1.2
Rest time, locomotor task time 10.81.01.6-1.0-1.1-0.9-1.1-1.1-0.8-1.1-0.9-1.0-0.9-0.9-0.9-1.0-1.0-0.8-1.1-1.0-0.9-0.9-1.0-1.31.3-0.5
Distance moved, locomotor task time 10.00.00.3-0.10.1-0.0-0.3-0.3-0.1-0.1-0.10.10.00.0-0.1-0.00.0-0.0-0.10.0-0.2-0.00.10.3-0.3-0.5
Vertical activity count, locomotor time 10.51.11.91.11.11.01.21.20.91.21.01.11.01.01.01.11.11.01.41.10.91.01.11.1-1.10.7
Time >=10cm from walls, locomotor time 20.40.60.8-0.8-0.8-0.8-0.8-0.8-0.7-0.9-0.7-0.7-0.9-0.7-0.7-0.8-0.8-0.8-0.9-0.8-0.6-0.6-0.8-0.70.7-0.1
Bouts of movement, locomotor time 22.43.84.22.01.92.01.91.91.91.92.02.01.91.92.02.02.01.91.82.01.92.02.02.0-2.01.2
Total resting periods, locomotor time 22.44.24.92.22.02.12.02.02.02.12.12.12.02.02.12.22.22.11.92.22.02.12.22.0-2.01.4
Rest time, locomotor task time 20.20.30.9-0.5-0.5-0.3-0.7-0.7-0.1-0.5-0.4-0.5-0.3-0.4-0.3-0.4-0.4-0.1-0.5-0.4-0.5-0.4-0.3-0.90.9-0.1
Distance moved, locomotor task time 20.10.10.3-0.3-0.2-0.3-0.4-0.4-0.5-0.3-0.4-0.1-0.3-0.3-0.4-0.2-0.2-0.4-0.2-0.2-0.4-0.3-0.20.1-0.1-0.5
Vertical activity count, locomotor time 20.10.20.50.40.40.30.70.70.10.50.30.40.30.30.30.40.40.20.70.40.30.30.40.6-0.60.2
Light reinforcement 10.71.62.8-1.3-1.3-1.2-1.6-1.6-0.9-1.6-1.2-1.3-1.1-1.0-1.1-1.1-1.2-0.9-1.5-1.1-1.3-1.1-1.0-1.31.3-1.7
Light reinforcement 20.00.00.10.20.10.2-0.0-0.00.2-0.10.10.20.10.30.10.20.20.2-0.10.20.00.30.30.4-0.40.2
Bone: marrow area5.812.717.13.73.63.63.43.43.63.43.73.53.53.53.73.53.43.33.43.44.03.63.23.6-3.64.1
Bone: maximum diameter1.73.25.81.81.81.91.61.62.11.61.82.01.92.01.81.71.61.91.61.61.81.81.51.6-1.62.4
Bone: maximum force12.922.925.24.94.94.94.74.74.84.74.94.84.84.84.94.84.84.74.64.85.05.04.65.0-5.04.0
Bone: maximum moment14.124.828.65.15.15.14.84.85.04.85.15.04.95.05.25.04.94.84.74.95.35.24.75.2-5.24.3
Mean time between licks in bursts0.30.71.5-0.8-0.8-0.8-1.2-1.2-0.7-1.2-0.7-0.8-0.8-0.7-0.6-0.7-0.7-0.7-1.2-0.6-0.4-0.5-0.6-0.40.4-1.1
Mean num. licks in bursts0.60.92.60.80.80.61.61.60.51.60.70.40.50.50.60.60.70.51.50.61.10.70.41.0-1.01.4
Cd content in liver0.30.30.5-0.5-0.5-0.4-0.7-0.7-0.5-0.7-0.4-0.4-0.5-0.5-0.4-0.5-0.5-0.6-0.5-0.5-0.3-0.5-0.5-0.60.6-0.7
Co content in liver0.10.10.3-0.3-0.2-0.20.20.2-0.50.1-0.4-0.1-0.2-0.4-0.5-0.3-0.2-0.40.3-0.3-0.6-0.5-0.3-0.40.40.1
Cu content in liver0.20.22.50.50.40.40.60.60.30.50.40.40.40.20.40.30.20.10.50.30.60.20.20.1-0.11.6
Fe content in liver1.72.13.7-1.4-1.4-1.4-1.8-1.8-1.2-1.9-1.5-1.3-1.3-1.3-1.4-1.5-1.6-1.5-1.7-1.5-1.3-1.3-1.5-1.31.3-0.7
K content in liver0.10.10.4-0.3-0.3-0.4-0.0-0.0-0.40.1-0.4-0.3-0.3-0.4-0.4-0.4-0.4-0.4-0.2-0.4-0.5-0.5-0.4-0.60.60.3
Mg content in liver0.10.20.2-0.4-0.4-0.4-0.3-0.3-0.4-0.2-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.4-0.4-0.3-0.5-0.4-0.50.50.3
Mn content in liver0.00.00.2-0.1-0.1-0.20.20.20.00.4-0.1-0.2-0.1-0.1-0.10.00.00.30.10.0-0.4-0.10.1-0.30.30.0
Na content in liver0.10.10.90.30.30.20.50.50.10.60.10.30.30.10.10.10.10.00.40.10.1-0.00.0-0.00.00.9
Rb content in liver1.11.31.9-1.2-1.1-1.0-0.9-0.9-1.0-1.0-1.1-1.0-1.1-1.1-1.2-1.3-1.3-1.1-0.9-1.3-1.0-1.2-1.4-1.41.4-0.1
Se content in liver3.34.04.8-2.1-1.9-2.0-2.0-2.0-1.9-1.8-2.0-1.8-1.8-1.9-2.0-2.1-2.1-1.9-2.0-2.1-2.0-2.1-2.1-2.22.2-1.6
Sr content in liver0.50.41.20.80.70.60.70.70.60.70.70.60.60.60.60.60.50.40.70.60.80.60.50.7-0.71.1
Zn content in liver0.91.01.4-1.0-1.0-0.9-1.2-1.2-0.9-1.1-0.9-1.0-1.0-1.0-0.9-1.1-1.1-1.1-1.2-1.1-0.7-1.1-1.1-1.11.1-0.3
Bone: minimum diameter7.112.914.93.83.73.73.23.23.83.23.73.73.63.73.73.63.53.63.33.63.93.73.53.7-3.73.3
Time in familiar zone, hab. session 10.10.10.20.00.20.20.40.40.20.50.20.20.20.20.10.20.30.30.50.2-0.00.00.20.2-0.2-0.2
Time in novel zone, hab. session 10.00.00.20.1-0.00.1-0.4-0.40.2-0.40.10.10.10.10.20.1-0.00.2-0.30.10.00.20.10.0-0.0-0.1
Total zone transitions, hab. session 10.10.11.3-0.2-0.4-0.3-0.1-0.1-0.3-0.2-0.2-0.3-0.2-0.2-0.3-0.00.10.00.10.1-0.8-0.30.3-0.20.2-1.2
Total locomotion distance, hab. session 10.40.61.5-0.8-0.9-0.8-0.7-0.7-0.8-0.8-0.7-0.9-0.8-0.8-0.8-0.7-0.6-0.7-0.6-0.6-0.9-0.8-0.5-0.70.7-1.2
Locomotion velocity, hab. session 10.30.41.3-0.6-0.7-0.7-0.6-0.6-0.7-0.6-0.6-0.7-0.7-0.7-0.6-0.5-0.5-0.5-0.4-0.5-0.7-0.6-0.4-0.50.5-1.1
Time in familiar zone, hab. session 21.81.92.91.31.41.41.71.71.41.71.41.31.31.31.31.31.41.41.71.31.41.31.21.3-1.31.0
Time in novel zone, hab. session 22.02.13.0-1.3-1.5-1.4-1.7-1.7-1.4-1.7-1.4-1.4-1.4-1.4-1.3-1.3-1.4-1.4-1.7-1.3-1.4-1.3-1.2-1.41.4-1.1
Total zone transitions, hab. session 20.30.40.6-0.5-0.6-0.6-0.8-0.8-0.5-0.7-0.6-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.8-0.5-0.7-0.5-0.4-0.50.5-0.5
Total locomotion distance, hab. session 20.70.91.4-0.9-1.0-1.0-1.2-1.2-0.9-1.2-0.9-0.9-0.9-0.9-0.8-0.8-0.9-0.9-1.1-0.9-0.8-0.9-0.8-0.70.7-0.9
Locomotion velocity, hab. session 20.40.51.0-0.7-0.7-0.7-1.0-1.0-0.7-1.0-0.7-0.7-0.7-0.7-0.6-0.7-0.7-0.8-1.0-0.7-0.6-0.7-0.7-0.50.5-0.6
Novel to familiar place preference ratio1.61.72.31.41.31.31.31.31.31.41.31.41.41.41.31.41.41.51.31.40.91.41.51.2-1.20.3
Novelty place preference1.01.11.51.11.01.01.11.11.11.21.01.21.11.11.11.11.11.21.01.10.61.11.20.9-0.90.1
Time in novel zone, NPP test0.70.81.20.90.80.80.90.90.91.00.81.00.90.90.91.01.01.10.91.00.40.91.10.7-0.7-0.1
Total zone transitions, NPP test2.84.05.0-2.0-2.1-2.1-2.2-2.2-2.0-2.2-2.0-1.9-1.9-2.0-2.0-1.9-1.9-1.9-2.2-1.9-2.2-2.0-1.7-2.02.0-1.6
Total locomotion distance, NPP test4.25.77.6-2.4-2.5-2.5-2.8-2.8-2.4-2.7-2.4-2.4-2.4-2.3-2.3-2.3-2.3-2.3-2.7-2.3-2.3-2.3-2.2-2.22.2-2.1
Locomotion velocity, NPP test2.84.05.6-2.0-2.0-2.0-2.4-2.4-1.9-2.3-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-2.3-1.9-1.9-1.9-1.8-1.81.8-1.6
Intraocular pressure5.37.69.6-2.8-2.8-2.8-2.4-2.4-3.1-2.5-2.8-2.8-2.9-3.0-2.9-2.9-2.8-3.0-2.5-2.8-2.5-2.9-2.9-2.82.8-1.8
Delta distance traveled before/after self-admin0.20.22.20.00.20.10.40.40.10.30.10.20.1-0.10.1-0.2-0.2-0.3-0.1-0.30.8-0.0-0.5-0.10.11.5
Delta ambulatory time before/after self-admin0.20.22.3-0.1-0.0-0.10.20.2-0.10.1-0.1-0.1-0.1-0.3-0.1-0.4-0.4-0.5-0.3-0.40.6-0.3-0.6-0.50.51.5
Parametrial fat weight0.41.01.6-1.3-0.9-0.9-1.0-1.0-1.2-1.1-1.0-0.8-1.0-1.1-1.0-1.2-1.0-1.2-0.9-1.2-0.7-1.0-1.2-0.80.8-0.9
Pavlov. Cond. lever latency0.50.61.3-0.7-0.8-0.8-1.1-1.1-0.7-1.1-0.7-0.8-0.9-0.8-0.7-0.8-0.9-0.9-1.1-0.8-0.3-0.6-0.9-0.30.3-0.3
Pavlov. Cond. magazine entry latency1.52.02.71.41.41.51.61.61.41.61.41.41.51.41.41.51.51.61.61.51.01.41.51.0-1.00.6
Pavlov. Cond. change in total contacts2.22.33.61.51.51.51.91.91.41.91.51.51.61.51.41.61.71.71.91.60.91.41.71.2-1.20.5
Pavlov. Cond. index score1.72.23.61.41.51.51.91.91.41.91.41.51.61.41.31.51.61.71.91.50.81.31.60.9-0.90.7
Pavlov. Cond. latency score1.51.93.41.31.41.41.81.81.31.81.31.41.51.31.21.41.51.51.81.40.71.11.50.8-0.80.7
Pavlov. Cond. lever contacts0.50.61.30.70.80.81.11.10.71.10.70.80.90.80.70.80.80.91.10.80.30.60.80.3-0.30.4
Pavlov. Cond. magazine entry number1.01.21.9-1.1-1.1-1.2-1.3-1.3-1.1-1.4-1.1-1.1-1.2-1.1-1.1-1.1-1.1-1.3-1.4-1.1-0.7-1.0-1.1-0.70.7-0.6
Pavlov. Cond. intertrial magazine entries5.36.47.7-2.6-2.6-2.6-2.3-2.3-2.8-2.4-2.6-2.5-2.7-2.7-2.6-2.6-2.5-2.7-2.3-2.5-2.4-2.7-2.5-2.42.4-2.3
Pavlov. Cond. lever-magazine prob. diff.2.12.63.91.61.61.72.02.01.62.01.61.61.81.61.51.71.71.92.01.70.91.41.81.1-1.10.8
Pavlov. Cond. response bias0.60.71.10.80.91.01.01.00.91.00.90.91.00.90.80.90.91.01.00.90.50.80.90.5-0.50.4
Pavlov. Cond. lever latency1.01.42.81.31.11.01.61.61.01.71.10.71.01.01.11.31.31.11.51.30.81.01.31.1-1.10.8
Pavlov. Cond. magazine entry latency0.60.71.9-0.8-0.6-0.6-1.3-1.3-0.7-1.4-0.6-0.3-0.6-0.5-0.6-0.8-0.8-0.8-1.3-0.8-0.2-0.5-0.8-0.40.4-1.1
Pavlov. Cond. change in total contacts0.60.91.90.91.01.10.90.91.00.80.91.41.21.10.91.01.01.10.91.00.60.91.10.8-0.80.1
Pavlov. Cond. index score0.50.61.7-0.8-0.6-0.5-1.2-1.2-0.6-1.3-0.7-0.2-0.5-0.5-0.6-0.8-0.8-0.7-1.2-0.9-0.4-0.6-0.8-0.60.6-0.9
Pavlov. Cond. latency score0.60.71.9-0.9-0.7-0.6-1.3-1.3-0.7-1.4-0.8-0.3-0.6-0.6-0.7-0.9-0.9-0.8-1.3-0.9-0.5-0.7-0.9-0.70.7-0.9
Pavlov. Cond. lever contacts0.81.22.6-1.1-0.9-0.8-1.5-1.5-0.8-1.6-1.0-0.6-0.8-0.8-0.9-1.2-1.2-1.0-1.4-1.2-0.7-0.9-1.2-1.01.0-0.7
Pavlov. Cond. magazine entry number0.10.10.40.30.10.10.60.60.20.60.2-0.10.10.10.20.30.30.20.60.3-0.10.10.30.0-0.00.6
Pavlov. Cond. intertrial magazine entries1.21.93.3-1.4-1.3-1.4-0.7-0.7-1.3-0.6-1.4-1.5-1.4-1.5-1.5-1.6-1.6-1.5-0.8-1.6-1.1-1.6-1.8-1.81.80.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.2-0.7-0.5-0.4-1.0-1.0-0.5-1.1-0.5-0.1-0.4-0.3-0.5-0.6-0.6-0.5-1.0-0.7-0.3-0.5-0.7-0.50.5-0.8
Pavlov. Cond. response bias0.50.61.7-0.9-0.6-0.5-1.2-1.2-0.6-1.3-0.7-0.3-0.5-0.5-0.6-0.8-0.8-0.7-1.1-0.9-0.3-0.6-0.9-0.60.6-0.8
Time in closed arm before self-admin1.21.52.31.21.21.11.21.21.21.21.21.11.21.31.21.41.41.41.21.40.81.31.51.4-1.40.2
Time in closed arm after self-admin0.40.40.90.60.60.60.60.60.70.70.60.60.70.70.60.70.80.90.70.80.10.60.90.4-0.4-0.4
Time in open arm before self-admin0.50.53.2-0.6-0.7-0.6-0.9-0.9-0.6-0.7-0.6-0.5-0.6-0.5-0.6-0.5-0.4-0.4-0.7-0.4-0.9-0.6-0.3-0.60.6-1.8
Time in open arm after self-admin0.40.40.5-0.6-0.6-0.7-0.5-0.5-0.7-0.6-0.6-0.6-0.7-0.7-0.7-0.6-0.6-0.7-0.6-0.6-0.5-0.7-0.6-0.60.6-0.5
Bone: periosteal estimation9.019.023.44.54.54.54.14.14.64.14.54.54.54.54.54.34.24.24.14.24.74.43.94.3-4.34.8
Bone: periosteal perimeter8.614.917.54.04.04.03.63.64.23.64.04.04.04.04.03.83.83.93.53.74.03.93.63.8-3.84.0
Bone: post-yield work5.58.110.53.02.92.92.52.52.92.63.02.82.82.93.02.92.82.72.52.83.23.02.63.1-3.12.7
Progressive ratio test 1 active lever presses7.18.810.3-3.1-2.9-3.0-3.2-3.2-3.0-3.1-3.0-3.0-3.0-3.0-2.9-3.1-3.1-3.2-3.1-3.1-2.6-2.8-3.2-2.42.4-2.7
Progressive ratio test 1 breakpoint6.98.59.8-3.0-2.9-2.9-3.1-3.1-2.9-3.1-2.9-2.9-3.0-2.9-2.9-3.1-3.1-3.1-3.0-3.1-2.5-2.8-3.1-2.32.3-2.7
Progressive ratio test 1 inactive lever presses0.50.71.7-0.8-0.8-0.9-1.3-1.3-0.9-0.9-0.8-0.7-0.9-0.8-0.8-0.8-0.8-0.9-1.0-0.8-0.7-0.7-0.7-0.30.3-0.9
Progressive ratio test 2 active lever presses1.41.73.1-1.3-1.2-1.2-1.8-1.8-1.3-1.4-1.3-1.2-1.3-1.3-1.2-1.4-1.4-1.5-1.4-1.4-1.0-1.2-1.4-0.80.8-0.9
Progressive ratio test 2 breakpoint1.31.52.9-1.2-1.1-1.1-1.7-1.7-1.2-1.3-1.2-1.1-1.2-1.2-1.2-1.3-1.3-1.3-1.3-1.3-1.0-1.1-1.3-0.70.7-1.0
Progressive ratio test 2 inactive lever presses0.60.92.0-0.8-0.8-0.8-1.4-1.4-1.0-1.1-0.8-0.8-0.9-1.0-0.8-1.0-1.0-1.2-1.1-1.0-0.4-0.9-1.1-0.70.7-0.1
Incentive Sensitization - Responses0.60.91.61.01.01.00.50.50.91.00.91.11.00.91.01.01.00.90.91.00.91.01.01.0-1.01.3
Incentive Sensitization - Breakpoint0.60.81.50.91.00.90.40.40.80.90.81.00.90.90.90.90.90.80.80.90.70.90.90.9-0.91.2
Sum of active levers in priming session hrs 5-60.10.10.3-0.3-0.3-0.2-0.3-0.3-0.1-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.0-0.4-0.2-0.4-0.2-0.1-0.60.6-0.2
Progressive ratio1.52.32.7-1.6-1.6-1.6-1.6-1.6-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.6-1.5-1.5-1.5-1.4-1.41.4-1.5
Food seeking constrained by brief footshock3.34.04.8-2.1-2.0-2.1-2.2-2.2-2.1-1.9-2.1-2.0-2.1-2.1-2.1-2.1-2.0-2.1-1.9-2.1-2.0-2.1-2.0-1.81.8-1.1
Seeking ratio, punishment vs. effort0.10.10.30.30.30.30.20.20.30.40.30.30.30.30.20.30.30.30.50.30.30.20.30.2-0.20.5
Retroperitoneal fat weight0.83.45.7-2.1-1.7-1.7-1.5-1.5-2.0-1.4-1.8-1.5-1.8-2.0-1.8-2.2-2.0-2.1-1.5-2.2-1.1-2.0-2.4-2.12.1-0.8
Reaction time number correct0.81.54.11.31.11.11.51.51.21.51.20.70.91.01.11.00.90.91.61.01.51.10.71.2-1.22.0
Reaction time mean minus median2.56.17.0-2.5-2.5-2.6-2.3-2.3-2.6-2.2-2.6-2.5-2.6-2.6-2.6-2.5-2.6-2.5-2.2-2.6-2.5-2.6-2.5-2.52.5-1.1
Reaction time mean minus median AUC1.64.15.2-2.1-2.1-2.2-1.7-1.7-2.3-1.6-2.2-2.1-2.2-2.2-2.2-2.1-2.1-2.1-1.6-2.0-2.3-2.2-2.0-2.12.1-1.1
Reaction time num false alarms1.52.02.9-1.4-1.6-1.4-1.6-1.6-1.4-1.6-1.4-1.4-1.4-1.4-1.3-1.3-1.3-1.3-1.5-1.2-1.4-1.3-1.2-1.51.5-1.7
Reaction time num false alarms AUC1.52.44.3-1.5-1.7-1.5-1.7-1.7-1.5-1.7-1.5-1.6-1.6-1.5-1.4-1.4-1.3-1.3-1.6-1.3-1.7-1.4-1.2-1.61.6-2.1
Reaction time trials correct on left0.81.54.11.31.11.11.51.51.21.51.20.70.91.01.11.00.90.91.61.01.51.10.71.2-1.22.0
Reaction time trials on left0.61.23.71.11.00.91.31.31.01.41.00.60.80.81.00.90.80.71.50.81.41.00.61.0-1.01.9
Reaction time mean0.50.91.1-0.9-0.9-0.8-0.9-0.9-0.9-1.0-0.9-0.8-0.9-0.9-0.9-1.0-1.0-1.0-1.0-1.0-0.7-1.0-1.0-1.01.0-0.4
Reaction time mean AUC0.30.50.7-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.7-0.5-0.7-0.7-0.7-0.7-0.8-0.8-0.7-0.8-0.5-0.8-0.8-0.80.8-0.2
Median of all reaction times0.00.00.1-0.1-0.00.0-0.2-0.2-0.1-0.3-0.10.1-0.0-0.1-0.1-0.2-0.2-0.2-0.3-0.20.1-0.2-0.3-0.30.3-0.0
Reaction time omissions7.611.112.2-3.3-3.4-3.5-3.2-3.2-3.5-3.1-3.4-3.4-3.5-3.5-3.5-3.3-3.4-3.4-3.2-3.3-3.3-3.5-3.3-3.43.4-2.2
Reaction time false alarm rate1.92.66.8-1.6-1.7-1.5-1.9-1.9-1.5-1.9-1.5-1.3-1.4-1.4-1.4-1.3-1.2-1.1-1.9-1.2-1.9-1.4-1.0-1.71.7-2.6
Reaction time premature initiation rate3.14.35.7-2.1-2.1-2.2-1.8-1.8-2.1-1.7-2.1-2.0-2.1-2.2-2.2-2.2-2.1-2.2-1.8-2.2-1.9-2.3-2.2-2.42.4-1.6
Reaction time premature initiations1.01.82.8-1.3-1.4-1.4-0.9-0.9-1.4-0.8-1.4-1.5-1.5-1.5-1.4-1.5-1.5-1.6-0.8-1.5-1.0-1.5-1.7-1.61.6-0.3
Std. dev. reaction times3.26.06.8-2.5-2.5-2.5-2.3-2.3-2.6-2.3-2.5-2.5-2.5-2.6-2.5-2.5-2.5-2.4-2.3-2.5-2.5-2.6-2.4-2.62.6-1.5
Reaction time trials completed0.61.23.71.11.00.91.31.31.01.41.00.60.80.81.00.90.80.71.50.81.41.00.61.0-1.01.9
Reaction time trials AUC1.02.04.41.51.31.31.71.71.41.71.40.91.11.21.31.21.11.11.81.21.71.30.91.4-1.42.1
Run reversals in cocaine runway, females0.40.41.40.60.60.40.60.60.40.60.60.40.40.40.50.50.50.30.40.50.80.50.40.8-0.81.2
Run reversals in cocaine runway, males0.40.41.0-0.5-0.6-0.7-0.6-0.6-0.7-0.4-0.7-0.7-0.7-0.7-0.7-0.5-0.5-0.6-0.4-0.5-1.0-0.6-0.4-0.50.5-0.6
Latency to leave start box in cocaine runway0.10.11.7-0.1-0.2-0.1-0.1-0.1-0.0-0.20.0-0.0-0.00.0-0.00.10.10.2-0.20.1-0.30.00.2-0.10.1-1.3
Latency to leave start box in cocaine runway, F1.01.24.1-1.1-1.1-1.1-1.1-1.1-1.1-1.2-1.0-1.1-1.1-1.0-1.1-0.9-0.9-0.8-1.1-0.8-1.3-0.9-0.7-0.80.8-2.0
Latency to leave start box in cocaine runway, M1.81.72.51.31.31.31.61.61.41.21.41.41.41.31.41.41.41.41.21.41.21.31.41.0-1.00.5
Std. dev. time between licks in bursts1.31.72.9-1.3-1.3-1.3-1.7-1.7-1.1-1.6-1.3-1.2-1.2-1.2-1.2-1.3-1.3-1.2-1.7-1.3-1.1-1.2-1.3-1.31.3-0.7
Total sessions with >9 infusions2.42.95.0-1.7-1.6-1.6-2.1-2.1-1.7-2.0-1.7-1.7-1.7-1.6-1.6-1.7-1.7-1.8-1.8-1.7-1.5-1.4-1.7-0.90.9-2.2
Short access day 1 total inactive lever presses1.62.13.2-1.4-1.4-1.5-1.8-1.8-1.5-1.5-1.4-1.4-1.5-1.4-1.4-1.5-1.5-1.5-1.5-1.5-1.3-1.3-1.5-0.80.8-1.7
Short access day 10 total inactive lever presses0.00.10.10.40.20.20.20.20.30.30.30.30.30.20.20.30.30.20.10.30.30.20.30.0-0.00.3
Short access day 1 total infusions1.21.62.7-1.3-1.1-1.1-1.7-1.7-1.2-1.4-1.3-1.1-1.2-1.2-1.2-1.4-1.5-1.5-1.3-1.4-0.8-1.1-1.5-0.60.6-1.0
Short access day 10 total infusions2.02.53.5-1.6-1.5-1.7-1.9-1.9-1.7-1.8-1.6-1.7-1.7-1.5-1.6-1.6-1.7-1.8-1.8-1.6-1.4-1.3-1.6-0.60.6-1.8
Short access total infusions3.34.35.7-2.1-1.9-2.0-2.4-2.4-2.1-2.3-2.1-2.1-2.1-2.0-2.0-2.2-2.3-2.4-2.2-2.3-1.6-1.8-2.4-1.21.2-1.7
Short access day 1 locomotion0.50.61.7-0.7-0.4-0.7-1.0-1.0-0.8-0.8-0.7-0.6-0.7-0.5-0.7-0.8-0.8-0.9-0.8-0.8-0.6-0.4-0.80.6-0.6-1.3
Short access day 10 total locomotion0.30.60.9-0.7-0.7-0.9-0.8-0.8-0.8-0.9-0.8-0.8-0.9-0.7-0.8-0.8-0.9-0.9-1.0-0.8-0.5-0.6-0.9-0.00.0-0.6
Short access total locomotion1.21.52.7-1.2-1.1-1.3-1.3-1.3-1.2-1.5-1.2-1.3-1.3-1.1-1.2-1.3-1.3-1.4-1.4-1.3-0.9-0.9-1.3-0.10.1-1.6
One hour access (0.3 mA shock)0.40.50.80.70.80.90.50.50.70.50.70.90.80.80.70.60.60.60.80.60.80.80.50.8-0.80.5
Compulsive drug intake0.50.50.80.70.70.90.40.40.80.50.70.90.80.80.70.80.80.90.80.80.50.80.90.7-0.70.6
One hour access (shock baseline)0.20.30.50.60.60.60.50.50.50.60.60.60.60.50.60.50.40.40.50.40.70.50.30.6-0.60.3
Social response proportion0.10.10.8-0.3-0.1-0.2-0.1-0.1-0.4-0.1-0.3-0.1-0.2-0.3-0.3-0.4-0.4-0.5-0.2-0.50.1-0.4-0.6-0.40.40.9
Social responses3.54.57.8-2.2-2.2-2.0-2.0-2.0-2.0-2.0-2.1-2.0-2.0-2.1-2.1-2.1-2.1-1.9-1.9-2.1-2.3-2.2-2.0-2.82.8-1.4
Social time0.30.43.20.60.60.70.50.50.70.50.70.60.60.50.70.50.40.40.50.41.00.60.30.2-0.21.8
Soleus weight0.92.63.11.61.71.71.51.51.71.51.61.71.71.71.61.51.51.61.41.51.71.71.41.7-1.71.8
Bone: stiffness17.528.531.85.55.55.45.05.05.45.05.55.55.45.55.65.45.45.34.95.45.55.65.35.6-5.64.3
Tibialis anterior weight4.013.619.03.63.63.64.04.03.84.03.63.83.93.93.53.94.14.44.04.12.13.54.43.1-3.10.9
Time to tail flick, vehicle, before self-admin1.41.54.3-1.1-1.3-0.9-1.4-1.4-1.0-1.2-1.1-1.1-1.0-1.2-1.0-1.1-1.1-1.0-1.0-1.1-1.1-1.3-1.0-2.12.1-0.6
Time to tail flick, vehicle, after self-admin0.30.40.60.60.60.70.60.60.70.50.60.50.70.70.60.60.60.80.70.60.40.70.70.7-0.7-0.2
Time to tail flick, test, before self-admin0.30.30.6-0.5-0.7-0.6-0.1-0.1-0.6-0.5-0.6-0.7-0.6-0.6-0.6-0.4-0.4-0.4-0.6-0.4-0.7-0.6-0.3-0.80.8-0.4
Time to tail flick, test, after self-admin0.70.81.01.00.90.80.60.60.90.80.90.90.80.91.01.00.90.90.71.01.01.01.01.0-1.00.5
Delta time to tail flick, vehicle, before/after SA0.80.81.90.81.00.90.90.90.80.80.80.90.80.90.80.70.70.70.90.70.90.90.71.4-1.40.5
Delta time to tail flick, test, before/after SA0.50.51.10.70.80.70.30.30.60.70.70.80.70.70.80.70.70.60.60.70.90.80.61.0-1.00.2
Tibia length4.011.116.43.43.73.73.23.23.33.13.53.83.73.33.53.23.12.83.13.14.03.22.83.2-3.23.3
Ambulatory time before self-admin2.02.93.5-1.9-1.8-1.8-1.6-1.6-1.7-1.7-1.8-1.8-1.8-1.7-1.8-1.9-1.9-1.8-1.7-1.8-1.8-1.7-1.8-1.41.4-1.3
Ambulatory time after self-admin1.82.23.6-1.5-1.4-1.5-1.1-1.1-1.4-1.3-1.5-1.5-1.4-1.6-1.5-1.7-1.7-1.7-1.6-1.8-0.9-1.5-1.9-1.51.50.2
Bone: tissue strength1.51.51.91.21.21.21.41.41.21.31.21.11.11.21.21.31.31.31.41.31.11.41.31.3-1.30.4
Total heroin consumption0.60.71.20.70.91.01.01.00.90.80.80.80.90.80.80.70.70.80.90.71.00.80.60.6-0.61.1
Bone: trabecular number3.05.07.72.42.32.12.42.42.02.52.22.12.12.02.22.12.11.82.32.12.62.11.92.4-2.42.8
Bone: trabecular spacing0.70.92.5-1.0-1.0-0.8-1.0-1.0-0.7-1.1-0.9-0.8-0.7-0.7-0.9-0.9-0.8-0.6-1.0-0.8-1.2-0.9-0.7-1.21.2-1.6
Bone: trabecular thickness0.40.50.90.80.70.50.90.90.51.00.60.60.60.60.60.80.80.70.80.80.40.60.90.8-0.80.6
Bone: trabecular tissue density0.81.22.61.00.90.90.30.31.20.31.11.11.11.31.21.31.31.40.31.30.51.31.61.3-1.3-1.1
Water consumed over 24 hours0.10.10.90.10.20.10.20.20.10.30.10.10.00.00.1-0.0-0.1-0.10.2-0.10.50.2-0.30.1-0.11.0
Number of responses in last shaping day0.10.10.80.0-0.0-0.2-0.1-0.1-0.1-0.20.0-0.1-0.10.1-0.10.10.10.0-0.00.1-0.10.20.10.8-0.8-0.9