Hub : Genes

Mertk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio NM_022943.1 0.04 0.03 9.9e-04 0.01 0.01 0 0 8.3e-03 1.3e-02 1.0e-01 1.3e-01
2 Adipose alternative polyA NM_022943.1 0.04 0.03 3.8e-04 0.01 0.01 0.01 0.02 1.2e-02 7.7e-03 2.4e-02 1.5e-03
3 Adipose isoform ratio XM_063284527.1 0.04 0.03 4.7e-04 0.02 0.02 0.01 0 6.4e-03 6.3e-03 7.1e-02 7.6e-02
4 Adipose alternative polyA XM_063284527.1 0.04 0.03 3.7e-04 0.01 0.01 0.01 0.02 1.2e-02 7.3e-03 6.8e-02 1.1e-03
5 Adipose gene expression Mertk 0.27 0.14 0.0e+00 0.17 0.18 0.18 0.15 5.4e-19 1.5e-19 3.2e-19 4.3e-16
6 IC gene expression Mertk 0.36 0.15 2.1e-11 0.18 0.19 0.18 0.19 4.2e-08 1.7e-08 3.8e-08 2.3e-08
7 pVTA gene expression Mertk 0.05 0.04 4.3e-03 0.01 0.02 0.02 0.02 1.0e-01 8.4e-03 5.3e-03 1.6e-02
8 Liver gene expression Mertk 0.14 0.08 2.7e-14 0.09 0.06 0.09 0.08 5.7e-10 1.7e-07 1.0e-09 1.5e-09
9 NAcc gene expression Mertk 0.12 0.07 6.0e-14 0.05 0.09 0.09 0.09 1.5e-07 2.7e-13 5.5e-14 6.2e-13
10 BLA mRNA stability Mertk 0.13 0.09 2.1e-04 0.02 0.06 0.06 0.05 3.3e-02 3.8e-04 4.4e-04 1.6e-03
11 Brain gene expression Mertk 0.27 0.15 5.6e-16 0.12 0.17 0.16 0.16 2.4e-11 1.5e-15 5.8e-15 3.5e-15
12 Adipose mRNA stability Mertk 0.07 0.05 1.8e-06 0.02 0.05 0.04 0.04 4.2e-03 6.7e-06 2.0e-05 3.7e-05
13 PL gene expression Mertk 0.21 0.16 3.8e-11 0.05 0.09 0.09 0.09 2.3e-06 3.6e-10 6.4e-10 1.2e-09
14 BLA gene expression Mertk 0.23 0.13 1.4e-07 0.08 0.13 0.11 0.11 6.2e-05 2.7e-07 1.7e-06 2.5e-06
15 NAcc mRNA stability Mertk 0.06 0.04 2.8e-06 0.02 0.03 0.03 0.02 5.1e-04 1.2e-05 3.4e-05 5.2e-04
16 IL mRNA stability Mertk 0.26 0.15 1.3e-03 0.06 0.08 0.04 0.08 1.6e-02 5.4e-03 4.7e-02 5.4e-03
17 Brain mRNA stability Mertk 0.22 0.17 3.0e-09 0.1 0.1 0.09 0.09 9.8e-10 2.7e-09 2.2e-08 4.1e-09
18 Liver mRNA stability Mertk 0.08 0.05 9.7e-08 0.07 0.05 0.06 0.06 8.5e-08 4.5e-06 1.6e-07 1.7e-07
19 OFC gene expression Mertk 0.31 0.17 4.7e-04 0.16 0.16 0.15 0.15 1.2e-04 1.3e-04 1.7e-04 2.1e-04
20 LHb gene expression Mertk 0.32 0.17 1.1e-03 0.09 0.08 0.05 0.08 3.4e-03 6.6e-03 3.1e-02 5.4e-03
21 PL mRNA stability Mertk 0.09 0.06 3.0e-06 0.04 0.04 0.04 0.04 9.5e-06 9.9e-06 8.1e-05 3.5e-05
22 OFC mRNA stability Mertk 0.38 0.17 2.3e-05 0.2 0.21 0.23 0.2 2.0e-05 1.3e-05 2.9e-06 1.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.32.24.22.02.0-2.0-2.02.12.01.61.51.71.71.71.61.41.41.41.00.20.50.50.50.6-0.1
Area under the delay curve0.20.30.6-0.7-0.70.70.7-0.6-0.6-0.7-0.6-0.5-0.5-0.5-0.4-0.4-0.4-0.4-0.3-0.5-0.2-0.2-0.2-0.10.1
BMI with tail0.20.82.90.30.7-0.6-0.7-0.3-0.4-0.90.8-0.5-0.7-0.8-0.8-0.9-0.9-0.9-1.0-1.7-1.1-1.2-1.2-1.2-1.2
BMI without tail1.23.89.21.52.6-2.3-2.70.20.1-0.42.8-0.6-0.8-1.0-1.1-1.4-1.6-1.6-1.9-2.4-2.3-2.5-2.5-2.6-3.0
Body weight1.15.016.23.34.0-3.9-4.02.12.11.43.91.31.00.80.70.30.10.0-0.6-1.8-1.4-1.6-1.6-1.5-2.8
Weight adjusted by age2.84.38.42.92.4-2.5-2.42.72.62.72.32.52.32.32.22.01.91.91.61.10.91.01.01.1-0.1
Bone surface1.12.13.61.91.6-1.7-1.61.91.91.81.41.81.71.71.61.51.41.41.20.80.80.80.80.80.2
Bone volume1.32.44.32.01.7-1.8-1.72.12.11.81.41.91.91.81.81.61.61.61.30.60.90.80.80.90.2
Breakpoint value in progressive ratio session0.20.30.90.50.8-0.9-0.80.50.40.51.00.30.20.10.1-0.1-0.1-0.1-0.20.1-0.5-0.5-0.5-0.5-0.8
Number of licking bursts0.30.41.70.50.8-0.6-0.8-0.1-0.0-0.40.9-0.4-0.3-0.1-0.3-0.1-0.4-0.5-0.7-1.3-0.8-0.8-0.8-0.7-0.9
Context. condit. distance diff. score2.63.14.92.11.5-1.6-1.42.22.22.21.12.12.12.22.12.12.01.91.81.01.31.41.41.30.6
Locomotion velocity, session 10.10.10.4-0.5-0.60.50.6-0.1-0.10.0-0.50.00.0-0.00.10.00.10.20.20.10.40.30.30.30.4
Locomotion distance, session 11.82.33.81.71.0-1.2-0.91.81.81.90.91.91.81.81.81.81.71.71.61.01.51.31.31.20.6
Locomotion velocity, session 20.00.00.4-0.1-0.30.20.3-0.2-0.2-0.3-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.6-0.1-0.0-0.0-0.0-0.1
Locomotion distance, session 22.23.15.52.31.8-2.0-1.72.32.32.11.62.22.22.12.11.81.81.81.50.41.01.01.01.00.1
Locomotion velocity, session 30.70.82.10.51.0-0.9-1.0-0.2-0.2-0.41.3-0.5-0.7-0.7-0.7-0.9-1.0-1.0-1.0-1.0-0.9-1.2-1.2-1.4-1.3
Locomotion distance, session 32.83.010.22.33.0-2.8-3.11.11.00.93.20.40.1-0.0-0.2-0.5-0.7-0.7-1.0-0.9-1.5-1.7-1.7-1.9-2.5
Stereotopy head waving bouts, day 32.63.17.6-0.6-1.51.21.50.60.71.3-2.01.11.31.41.51.61.81.82.02.82.32.32.32.32.5
Stereotopy head waving duration, day 31.01.23.6-1.5-1.81.61.8-0.5-0.5-0.0-1.9-0.20.00.10.20.30.50.50.71.41.01.11.11.21.6
Locomotion velocity, session 71.21.33.21.81.8-1.8-1.71.31.41.71.61.11.01.00.90.90.70.60.30.90.0-0.1-0.1-0.0-0.8
Locomotion distance, session 73.44.38.32.92.5-2.6-2.52.72.82.52.02.42.42.42.32.22.01.91.60.90.90.90.91.0-0.1
Stereotopy head waving bouts, day 71.01.11.9-0.6-0.20.30.1-1.1-1.1-0.50.3-1.2-1.3-1.3-1.3-1.3-1.4-1.4-1.3-0.2-1.2-1.2-1.2-1.3-1.1
Stereotopy head waving duration, day 70.91.11.8-1.0-0.70.80.7-1.3-1.3-0.9-0.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.1-0.2-0.8-0.9-0.9-0.9-0.6
Locomotion velocity, session 80.80.92.61.00.7-1.0-0.71.21.21.60.91.11.21.11.11.01.01.00.81.00.40.50.50.50.0
Locomotion distance, session 85.98.614.73.83.0-3.3-2.93.83.83.62.53.53.53.43.33.23.02.92.61.21.81.81.81.70.3
Degree of sensitization distance2.62.65.10.2-0.50.30.61.21.31.2-1.11.41.71.81.82.12.12.02.01.51.92.12.12.31.9
Degree of sensitization stereotypy1.51.63.40.20.8-0.7-0.9-0.7-0.7-0.51.4-1.0-1.2-1.2-1.2-1.4-1.5-1.5-1.6-1.1-1.7-1.7-1.7-1.8-1.8
Conditioned locomotion1.31.62.81.61.3-1.4-1.31.71.61.41.11.61.51.41.41.21.21.21.20.50.90.90.90.70.1
Cocaine response after cond. corrected0.20.20.7-0.1-0.40.20.40.20.20.4-0.30.30.40.40.40.50.50.50.70.50.50.80.80.60.6
Cocaine response after cond. not corrected0.10.20.5-0.4-0.60.50.6-0.1-0.10.3-0.50.10.10.10.10.20.20.20.40.70.40.60.60.40.5
Cocaine response before conditioning0.30.30.5-0.6-0.50.60.5-0.7-0.7-0.5-0.5-0.5-0.7-0.7-0.7-0.7-0.6-0.6-0.70.1-0.3-0.5-0.5-0.3-0.1
Saline control response1.82.47.62.52.8-2.7-2.71.81.81.72.71.41.21.01.00.60.50.50.4-0.2-0.2-0.2-0.2-0.5-1.3
Bone: connectivity density0.61.01.81.21.2-1.3-1.21.41.41.20.91.21.21.11.11.00.90.90.80.50.50.50.50.50.1
Bone: cortical apparent density1.01.33.9-0.8-0.00.1-0.0-0.8-0.9-1.40.1-1.2-1.1-1.2-1.2-1.4-1.2-1.2-1.3-2.0-1.6-1.3-1.3-1.2-1.0
Bone: cortical area1.31.95.42.12.3-2.3-2.31.81.71.52.31.31.21.11.10.70.70.70.4-0.3-0.4-0.2-0.2-0.2-1.1
Bone: cortical porosity5.35.78.6-1.8-1.01.21.0-2.5-2.6-2.9-0.1-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.8-2.9-2.6-2.6-2.6-2.4-1.9
Bone: cortical porosity3.53.87.1-1.1-0.40.50.4-1.8-1.9-2.20.4-2.1-2.1-2.1-2.1-2.2-2.2-2.2-2.4-2.7-2.4-2.3-2.3-2.1-1.9
Bone: cortical thickness0.20.41.10.40.9-0.9-0.90.40.3-0.01.0-0.00.0-0.2-0.1-0.5-0.3-0.3-0.5-1.0-1.0-0.7-0.7-0.7-1.0
Bone: cortical thickness0.30.30.9-0.10.3-0.3-0.3-0.3-0.3-0.50.6-0.5-0.5-0.5-0.5-0.6-0.6-0.6-0.6-1.0-0.9-0.6-0.6-0.7-0.8
Bone: cortical tissue density0.91.23.5-0.9-0.20.20.1-0.9-0.9-1.5-0.1-1.2-1.1-1.2-1.2-1.4-1.2-1.2-1.2-1.9-1.5-1.2-1.2-1.1-0.9
Condit. Reinf. active minus inactive responses0.20.20.40.30.7-0.5-0.70.10.0-0.30.5-0.0-0.2-0.3-0.3-0.5-0.3-0.3-0.3-0.7-0.6-0.4-0.4-0.6-0.5
Condit. Reinf. active-inactive response ratio0.40.40.80.90.9-0.9-0.90.90.90.60.60.80.70.60.60.40.50.50.60.20.30.40.40.20.0
Condit. Reinf. active responses0.10.10.30.20.4-0.3-0.40.10.0-0.20.4-0.0-0.1-0.2-0.2-0.3-0.2-0.2-0.3-0.5-0.6-0.4-0.4-0.4-0.4
Condit. Reinf. inactive responses0.00.10.20.1-0.20.10.20.20.20.3-0.20.30.30.30.30.30.40.40.10.1-0.10.10.10.30.2
Incentive salience index mean0.10.10.30.50.6-0.5-0.60.60.50.20.30.50.40.30.40.20.30.40.3-0.10.00.20.20.10.0
Condit. Reinf. lever presses0.10.20.40.50.4-0.4-0.40.60.60.40.30.60.60.50.50.50.50.50.40.00.10.30.30.30.1
Condit. Reinf. active minus inactive responses1.92.45.52.42.2-2.2-2.22.02.02.11.91.81.61.51.41.21.21.20.70.90.30.10.10.3-0.7
Condit. Reinf. active-inactive response ratio2.22.56.32.52.4-2.4-2.42.02.02.02.11.71.61.51.41.21.11.10.80.70.40.20.20.2-0.7
Condit. Reinf. active responses1.72.46.12.52.5-2.4-2.52.01.92.02.21.71.51.31.30.91.00.90.50.50.0-0.1-0.1-0.0-1.0
Condit. Reinf. inactive responses0.10.10.40.50.5-0.6-0.50.50.40.60.50.40.40.30.30.20.20.20.00.2-0.2-0.2-0.20.0-0.3
Condit. Reinf. lever presses0.50.72.11.31.4-1.3-1.40.90.81.11.40.70.50.40.30.20.20.1-0.20.4-0.3-0.5-0.5-0.4-0.9
Condit. Reinf. lever reinforcers received1.72.35.72.42.3-2.3-2.32.01.92.02.01.71.51.31.31.01.11.00.60.70.20.10.10.2-0.8
Conditioned reinforcement - actives0.40.71.50.20.7-0.4-0.7-0.4-0.4-0.60.8-0.7-0.7-0.7-0.8-0.8-0.9-0.9-1.0-1.1-1.2-1.1-1.1-1.1-1.2
Conditioned reinforcement - inactives1.92.94.61.71.0-1.3-1.02.12.02.10.92.12.12.22.12.02.02.01.71.31.31.31.31.60.7
Conditioned locomotion0.30.41.10.10.4-0.4-0.5-0.3-0.2-0.50.7-0.5-0.5-0.5-0.5-0.6-0.6-0.6-0.8-1.0-1.0-0.9-0.9-0.8-0.9
Patch foraging indifference point 0 sec1.32.53.91.20.2-0.5-0.21.51.51.90.21.81.71.81.81.91.81.81.92.01.81.81.81.71.4
Patch foraging indifference point AUC0.30.41.21.11.0-1.0-1.00.80.70.61.10.70.50.50.40.30.30.30.2-0.10.1-0.1-0.1-0.1-0.4
Delay disc. indifference point, 0s delay2.12.36.0-2.4-2.52.42.4-1.9-1.9-1.9-2.2-1.5-1.4-1.3-1.1-1.0-0.9-0.8-0.2-0.70.40.30.30.11.1
Delay disc. indifference point, 16s delay0.10.10.6-0.5-0.60.60.6-0.3-0.3-0.2-0.8-0.2-0.1-0.1-0.10.00.00.00.10.40.30.30.30.30.5
Delay disc. indifference point, 2s delay0.00.00.10.0-0.30.30.3-0.2-0.2-0.2-0.2-0.0-0.1-0.0-0.00.1-0.0-0.00.1-0.20.10.20.20.20.1
Delay disc. indifference point, 24s delay0.40.51.5-0.9-1.21.21.2-0.9-0.8-0.4-1.2-0.6-0.5-0.5-0.5-0.4-0.3-0.3-0.30.50.00.00.00.20.4
Delay disc. indifference point, 4s delay0.40.52.4-0.4-0.10.00.1-0.5-0.5-1.00.3-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.7-1.5-0.8-0.8-0.8-0.7-0.6
Delay disc. indifference point, 8s delay0.40.50.8-0.8-0.50.50.5-0.8-0.8-0.9-0.5-0.8-0.8-0.7-0.8-0.7-0.7-0.7-0.8-0.7-0.6-0.7-0.7-0.5-0.3
Indifference point function ln k0.30.40.80.90.7-0.7-0.70.90.90.80.30.80.80.80.80.70.70.70.60.40.40.40.40.50.2
Indifference point function log k0.30.40.80.90.7-0.7-0.70.90.90.80.30.80.80.80.80.70.70.70.60.40.40.40.40.50.2
Patch foraging total patch changes 0 sec1.42.73.91.30.3-0.6-0.31.61.61.90.21.91.81.91.91.91.91.92.01.91.91.81.81.71.4
Patch foraging total patch changes 12 sec0.00.00.20.20.0-0.1-0.00.10.00.20.30.20.10.10.10.10.00.00.10.40.10.10.1-0.0-0.1
Patch foraging total patch changes 18 sec1.21.84.50.4-0.60.30.70.70.81.2-0.61.31.21.31.41.51.51.41.61.82.11.71.71.61.7
Patch foraging total patch changes 24 sec2.13.56.70.7-0.60.30.71.31.41.6-0.71.91.92.12.12.42.32.22.31.82.62.42.42.52.1
Patch foraging total patch changes 6 sec1.72.53.91.70.9-1.1-0.91.81.82.00.62.01.81.81.81.81.81.71.71.71.61.51.51.30.9
Patch foraging time to switch 0 sec2.65.49.8-3.1-2.52.62.4-3.0-3.0-2.9-2.0-2.8-2.7-2.7-2.6-2.4-2.3-2.3-2.0-1.2-1.4-1.4-1.4-1.4-0.3
Patch foraging water rate 0 sec3.06.413.13.62.9-3.1-2.83.43.32.72.53.12.92.92.82.52.42.42.10.31.61.31.31.20.2
Patch foraging water rate 12 sec0.91.93.71.91.2-1.5-1.21.81.81.61.21.71.61.61.61.51.51.41.30.51.00.90.90.80.4
Patch foraging water rate 18 sec0.10.20.80.70.9-0.8-0.90.50.40.10.70.30.20.10.1-0.00.00.0-0.0-0.7-0.4-0.2-0.2-0.3-0.4
Patch foraging water rate 24 sec0.30.41.41.21.2-1.1-1.20.60.60.11.20.40.30.30.20.10.0-0.0-0.1-0.8-0.2-0.3-0.3-0.5-0.7
Patch foraging water rate 6 sec1.01.54.12.01.9-2.0-1.91.51.51.21.81.31.11.11.00.80.70.70.5-0.40.2-0.1-0.1-0.1-0.6
Seeking ratio, delayed vs. immediate footshock0.00.10.2-0.3-0.40.40.4-0.3-0.2-0.1-0.4-0.1-0.2-0.1-0.1-0.1-0.1-0.00.00.30.10.10.10.20.2
Distance traveled before self-admin2.93.87.22.52.6-2.7-2.62.72.62.22.12.32.32.22.11.81.81.71.40.50.80.80.80.8-0.2
Distance traveled after self-admin0.70.92.91.41.7-1.7-1.71.01.00.71.50.70.60.50.40.30.20.2-0.1-0.5-0.5-0.5-0.5-0.5-1.0
Extensor digitorum longus weight0.10.42.70.20.7-0.6-0.70.00.0-0.60.9-0.4-0.2-0.2-0.3-0.3-0.4-0.4-0.5-1.6-0.8-0.6-0.6-0.7-0.8
Bone: elastic displacement1.82.03.9-0.6-0.00.2-0.0-1.3-1.3-1.20.5-1.4-1.6-1.6-1.6-1.6-1.7-1.7-1.8-1.6-2.0-1.8-1.8-1.6-1.6
Bone: elastic work0.81.01.9-0.5-0.00.10.0-0.9-0.9-0.80.4-0.9-1.1-1.1-1.1-1.2-1.2-1.2-1.3-0.9-1.4-1.3-1.3-1.2-1.1
Bone: endosteal estimation1.32.86.72.62.0-2.0-2.02.02.02.11.92.01.71.81.71.71.51.41.31.01.20.80.80.70.0
Bone: endosteal perimeter2.04.39.73.12.7-2.7-2.72.62.62.62.32.52.22.22.11.91.81.71.51.11.20.90.90.8-0.2
Epididymis fat weight0.10.50.9-0.9-0.80.90.7-0.9-0.9-0.6-0.8-0.8-0.9-0.8-0.8-0.7-0.7-0.7-0.50.50.0-0.3-0.3-0.40.1
Delta time in closed arm before/after self-admin0.20.20.4-0.4-0.50.50.5-0.6-0.6-0.6-0.5-0.6-0.5-0.5-0.5-0.4-0.4-0.4-0.3-0.6-0.2-0.2-0.2-0.2-0.1
Delta time in open arm before/after self-admin1.31.32.41.10.7-0.8-0.71.41.31.60.61.41.41.31.31.21.31.31.21.31.11.11.11.10.6
Diff in mean of infusions in LGA sessions0.20.20.8-0.9-0.90.70.9-0.5-0.5-0.3-0.8-0.4-0.3-0.2-0.3-0.1-0.1-0.1-0.00.40.20.20.20.20.5
Delay discount exponential model param0.20.30.50.60.6-0.6-0.60.60.60.70.50.60.50.50.50.40.40.40.40.60.30.30.30.20.0
Extinction: sum of active levers before priming0.20.30.50.10.1-0.1-0.1-0.3-0.4-0.40.2-0.4-0.5-0.6-0.5-0.6-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.6
Active lever presses in extinction session 60.20.20.5-0.2-0.40.20.40.20.20.3-0.30.40.40.50.50.50.40.50.60.40.70.70.70.70.7
Bone: final force1.42.26.12.32.4-2.5-2.41.91.81.62.41.41.41.31.20.90.80.80.3-0.2-0.2-0.3-0.3-0.1-1.1
Bone: final moment1.11.85.02.22.2-2.2-2.21.71.71.42.21.31.21.21.10.80.70.70.3-0.2-0.2-0.3-0.3-0.1-1.0
Food consumed during 24 hour testing period0.30.41.2-0.3-0.60.60.70.00.1-0.2-0.90.20.40.40.40.60.60.60.70.20.80.90.90.91.1
Glucose0.20.30.70.80.6-0.7-0.60.70.70.40.50.60.60.60.60.50.50.50.2-0.10.40.00.00.2-0.1
Heart weight5.78.717.14.13.4-3.6-3.43.93.93.82.93.63.53.33.22.92.92.82.21.51.31.31.31.5-0.1
Delay discount hyperbolic model param0.20.20.50.60.6-0.6-0.60.60.60.70.50.50.40.40.40.30.40.30.30.60.20.20.20.1-0.0
Intermittent access intake day 1-15 change0.20.51.50.81.0-0.8-1.00.0-0.00.21.2-0.1-0.3-0.2-0.3-0.5-0.6-0.5-0.7-0.4-0.8-0.9-0.9-0.9-1.1
Intermittent access intake escalation0.30.71.70.61.0-0.8-1.0-0.1-0.20.01.3-0.3-0.5-0.5-0.6-0.7-0.8-0.8-0.9-0.6-1.0-1.1-1.1-1.1-1.3
Intermittent access intake escalation 20.50.61.40.40.8-0.6-0.8-0.2-0.3-0.30.9-0.4-0.6-0.6-0.6-0.8-0.8-0.8-1.0-0.8-1.1-1.1-1.1-1.0-1.2
Intermitt. access day 1 inactive lever presses0.41.74.12.01.7-1.7-1.71.71.61.91.61.51.41.41.31.11.11.10.70.70.40.30.30.5-0.5
Intermitt. access day 15 inactive lever presses2.34.77.32.00.8-1.1-0.82.32.32.50.52.52.52.72.62.72.52.52.42.22.22.22.22.31.5
Intermitt. access escalation Index0.30.41.50.70.8-0.8-0.80.10.10.11.2-0.1-0.2-0.3-0.3-0.4-0.4-0.4-0.6-0.7-0.9-0.9-0.9-0.8-1.1
Intermittent access day 1 total infusions0.10.20.80.30.4-0.3-0.4-0.0-0.0-0.40.4-0.2-0.1-0.1-0.2-0.2-0.2-0.2-0.5-0.9-0.6-0.5-0.5-0.3-0.5
Intermittent access day 15 total infusions0.40.52.01.21.3-1.2-1.30.50.50.41.40.30.20.20.1-0.0-0.1-0.1-0.3-0.6-0.7-0.6-0.6-0.6-1.0
Intermittent access terminal intake (last 3 days)0.40.51.31.01.1-1.1-1.10.80.80.61.10.60.60.60.60.40.40.40.1-0.3-0.3-0.2-0.20.0-0.5
Intermittent access total infusions0.50.51.41.21.2-1.2-1.20.90.90.71.10.70.70.70.70.60.50.50.2-0.3-0.3-0.1-0.10.1-0.5
Intermittent access day 1 locomotion0.40.61.41.11.2-1.2-1.21.01.00.61.00.70.80.70.70.60.50.50.2-0.4-0.2-0.1-0.10.1-0.4
Intermittent access day 15 total locomotion0.71.22.01.00.7-0.9-0.71.41.41.30.61.31.41.41.41.21.31.31.11.00.80.90.91.00.5
Intermittent access total locomotion1.01.22.81.61.6-1.7-1.61.51.51.11.51.21.21.21.10.90.80.90.5-0.00.00.10.10.2-0.4
Intermittent access standard deviation0.20.41.41.11.2-0.9-1.20.60.60.70.90.50.40.40.30.20.20.20.10.1-0.3-0.2-0.2-0.2-0.5
Left kidney weight1.78.112.51.80.4-0.8-0.42.72.83.2-0.13.13.23.33.33.43.43.33.53.03.43.43.43.12.6
Right kidney weight1.67.210.91.60.3-0.8-0.32.62.73.1-0.22.93.13.13.13.33.23.23.32.93.13.13.13.02.4
Cocaine induced anxiety2.02.87.8-1.8-2.62.42.6-0.8-0.70.0-2.8-0.10.00.20.30.70.70.71.42.52.02.02.01.72.6
Post-drug Anxiety1.41.54.5-1.3-1.91.81.9-0.8-0.7-0.1-2.1-0.2-0.10.00.10.40.40.40.91.71.41.41.41.21.8
Baseline Anxiety0.30.30.90.60.8-0.5-0.8-0.0-0.1-0.20.7-0.2-0.3-0.3-0.3-0.4-0.4-0.4-0.6-1.0-0.8-0.7-0.7-0.7-0.9
Tail length1.66.118.04.04.2-4.1-4.22.92.92.94.12.21.91.81.61.31.11.00.50.1-0.5-0.5-0.5-0.7-2.0
Length with tail2.711.829.35.45.4-5.4-5.44.44.34.25.13.53.33.12.92.42.22.11.30.50.0-0.0-0.0-0.0-2.0
Length without tail1.65.210.13.22.7-2.8-2.73.13.12.82.32.82.72.62.52.32.22.21.70.61.01.01.01.1-0.1
Times rat made contact with spout0.00.00.1-0.1-0.20.20.2-0.1-0.1-0.1-0.3-0.0-0.00.10.00.10.10.10.20.10.30.20.20.20.3
Lifetime Intake0.40.51.21.11.1-1.1-1.10.90.90.61.00.70.70.80.70.60.50.50.2-0.3-0.2-0.0-0.00.2-0.4
Liver weight, left0.91.53.11.81.5-1.6-1.51.61.61.41.41.41.41.51.41.31.21.20.90.10.50.50.50.6-0.2
Liver weight, right0.10.20.40.40.6-0.6-0.60.60.60.70.30.40.50.40.40.30.40.40.20.5-0.10.10.10.1-0.1
Locomotor activity0.30.41.41.01.0-1.0-0.90.50.50.91.20.50.20.10.2-0.0-0.0-0.0-0.20.4-0.5-0.5-0.5-0.4-0.8
Locomotor testing distance0.30.52.10.70.1-0.3-0.10.70.71.30.20.90.70.70.80.70.80.70.81.50.60.70.70.70.5
Locomotor testing rearing1.12.25.21.61.0-1.2-1.01.81.82.30.81.81.71.61.71.51.61.61.52.11.01.21.21.20.6
Locomotion in novel chamber0.50.61.70.61.0-1.0-1.00.10.10.11.1-0.2-0.3-0.3-0.4-0.5-0.6-0.6-0.8-0.6-1.1-1.1-1.1-1.0-1.3
Locomotion in novel chamber post-restriction0.61.12.50.31.0-0.8-1.0-0.2-0.3-0.41.1-0.6-0.7-0.8-0.8-1.0-1.0-1.0-1.3-1.3-1.5-1.5-1.5-1.4-1.6
Fecal boli incidents, locomotor time 10.40.61.0-0.6-0.30.40.2-0.8-0.8-0.8-0.2-0.9-0.8-1.0-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.7
Change in fecal boli incidents, locomotor task0.10.10.2-0.4-0.50.30.5-0.1-0.2-0.1-0.2-0.0-0.00.00.00.00.00.10.20.10.30.30.30.20.4
Time >=10cm from walls, locomotor time 10.90.92.6-0.00.5-0.5-0.6-0.4-0.4-0.70.8-0.8-0.7-0.8-0.8-0.9-0.9-0.9-1.2-1.6-1.3-1.3-1.3-1.2-1.4
Bouts of movement, locomotor time 12.42.86.3-2.4-2.52.52.5-2.2-2.2-1.7-2.3-1.7-1.8-1.7-1.6-1.5-1.4-1.2-0.70.2-0.1-0.0-0.0-0.30.7
Total resting periods, locomotor time 12.62.95.8-2.3-2.42.42.4-2.3-2.3-1.8-2.1-1.9-1.9-1.9-1.8-1.7-1.5-1.4-0.9-0.0-0.4-0.3-0.3-0.50.4
Rest time, locomotor task time 10.60.71.2-1.0-0.80.80.8-1.1-1.1-1.0-0.7-1.1-1.0-1.0-1.0-0.9-0.9-0.9-0.9-0.5-0.7-0.7-0.7-0.6-0.3
Distance moved, locomotor task time 10.00.00.10.20.1-0.0-0.10.20.2-0.1-0.10.10.20.10.10.10.20.10.1-0.30.20.20.20.10.1
Vertical activity count, locomotor time 10.10.30.60.70.6-0.6-0.60.70.70.50.30.60.60.60.60.50.60.60.5-0.20.40.40.40.30.1
Time >=10cm from walls, locomotor time 20.10.10.60.60.6-0.5-0.60.10.1-0.10.8-0.1-0.1-0.0-0.1-0.0-0.2-0.20.0-0.7-0.1-0.1-0.1-0.5-0.4
Bouts of movement, locomotor time 21.01.72.6-1.4-0.80.90.8-1.5-1.6-1.6-0.6-1.5-1.6-1.6-1.6-1.5-1.6-1.5-1.3-1.0-1.1-1.1-1.1-1.3-0.6
Total resting periods, locomotor time 21.22.23.3-1.5-0.80.80.7-1.7-1.7-1.8-0.5-1.7-1.8-1.8-1.8-1.8-1.8-1.8-1.5-1.3-1.4-1.4-1.4-1.5-0.9
Rest time, locomotor task time 21.51.92.7-1.6-0.90.90.9-1.4-1.5-1.6-0.6-1.6-1.4-1.5-1.5-1.6-1.4-1.4-1.6-1.6-1.6-1.4-1.4-1.0-0.9
Distance moved, locomotor task time 20.91.12.40.80.1-0.1-0.10.90.90.8-0.31.11.11.21.21.21.21.21.40.91.51.41.41.21.2
Vertical activity count, locomotor time 21.11.52.31.40.6-0.5-0.51.21.21.30.11.31.31.41.41.41.31.31.51.21.51.51.51.21.0
Light reinforcement 10.20.51.91.01.2-1.1-1.20.70.70.71.40.40.50.40.40.30.20.2-0.0-0.1-0.3-0.3-0.3-0.3-0.8
Light reinforcement 20.10.20.60.60.8-0.7-0.80.50.50.30.60.30.30.30.30.20.20.20.0-0.20.1-0.1-0.1-0.1-0.3
Bone: marrow area1.32.86.52.62.0-2.0-2.02.02.02.11.82.01.81.81.71.81.51.41.41.01.20.90.90.70.1
Bone: maximum diameter2.44.410.63.33.0-3.1-3.02.72.72.62.92.42.22.12.01.71.61.51.20.30.40.50.50.4-0.8
Bone: maximum force0.51.01.91.41.2-1.4-1.21.31.31.31.21.11.11.11.00.90.90.90.60.40.30.20.20.4-0.2
Bone: maximum moment0.40.71.21.10.9-1.1-0.91.11.11.00.80.91.00.90.90.80.80.80.60.30.30.30.30.40.0
Mean time between licks in bursts0.30.61.1-0.8-0.50.50.4-0.9-0.9-1.0-0.2-1.0-0.9-0.9-0.9-0.9-0.9-0.9-0.8-1.0-0.9-0.7-0.7-0.7-0.6
Mean num. licks in bursts0.60.92.9-0.4-0.90.70.90.30.20.7-1.20.70.60.50.70.60.80.91.11.71.41.31.31.11.5
Cd content in liver0.70.83.31.31.8-1.7-1.80.80.70.71.80.50.20.20.1-0.1-0.2-0.2-0.10.10.0-0.4-0.4-0.8-0.9
Co content in liver0.91.03.61.41.9-1.7-1.90.70.70.41.90.30.10.0-0.1-0.3-0.3-0.4-0.5-0.9-0.6-0.9-0.9-1.0-1.4
Cu content in liver1.01.24.51.62.1-1.9-2.11.00.90.92.10.60.30.30.2-0.1-0.2-0.2-0.2-0.2-0.4-0.7-0.7-0.9-1.4
Fe content in liver0.20.20.80.50.7-0.6-0.70.20.20.50.90.1-0.0-0.1-0.1-0.1-0.2-0.2-0.40.3-0.3-0.6-0.6-0.4-0.7
K content in liver0.30.30.70.80.8-0.8-0.80.70.60.70.80.60.50.50.50.30.30.30.10.2-0.1-0.1-0.1-0.0-0.5
Mg content in liver1.11.13.81.41.8-1.8-1.80.90.80.81.90.50.40.30.2-0.1-0.1-0.1-0.4-0.4-0.8-0.9-0.9-0.8-1.5
Mn content in liver1.31.44.21.92.0-2.0-2.01.41.31.42.11.00.90.80.70.50.40.40.10.0-0.3-0.4-0.4-0.4-1.1
Na content in liver0.30.30.80.0-0.40.30.40.20.20.4-0.40.40.50.60.60.70.60.60.60.70.90.70.70.80.7
Rb content in liver1.01.23.51.51.9-1.9-1.91.41.31.11.80.90.90.80.70.30.40.5-0.0-0.0-0.1-0.4-0.4-0.3-1.0
Se content in liver0.91.13.21.81.7-1.6-1.71.31.30.91.61.10.90.80.80.60.60.60.4-0.3-0.10.00.0-0.0-0.6
Sr content in liver0.60.51.51.11.2-1.1-1.20.70.80.91.20.50.50.50.30.40.30.20.00.2-0.4-0.3-0.3-0.3-0.7
Zn content in liver0.30.30.90.61.0-0.9-1.00.30.30.30.90.2-0.0-0.1-0.1-0.4-0.3-0.3-0.4-0.1-0.2-0.6-0.6-0.7-0.8
Bone: minimum diameter0.71.23.31.81.7-1.8-1.71.41.41.41.71.21.01.00.90.70.70.60.50.10.00.10.1-0.0-0.7
Time in familiar zone, hab. session 10.40.40.9-0.8-0.70.70.7-0.8-0.8-0.4-0.4-0.8-0.7-0.6-0.7-0.5-0.6-0.6-0.7-0.4-0.9-0.5-0.5-0.2-0.3
Time in novel zone, hab. session 11.21.22.60.80.5-0.6-0.51.21.20.8-0.11.31.31.21.21.21.31.31.31.01.61.21.21.01.0
Total zone transitions, hab. session 11.21.73.11.61.1-1.3-1.11.61.61.81.31.51.51.61.51.51.41.31.30.50.91.01.00.90.2
Total locomotion distance, hab. session 13.14.39.52.11.0-1.4-1.02.32.33.11.12.52.42.52.52.52.32.32.22.31.81.91.91.80.9
Locomotion velocity, hab. session 13.04.39.02.11.0-1.4-1.02.32.33.01.22.52.42.42.42.42.32.32.32.21.81.91.91.80.9
Time in familiar zone, hab. session 20.40.41.4-0.9-1.11.11.1-0.6-0.6-0.2-1.2-0.4-0.3-0.3-0.2-0.1-0.0-0.00.00.70.10.30.30.40.6
Time in novel zone, hab. session 20.40.41.40.91.1-1.1-1.10.60.6-0.01.20.30.30.20.20.1-0.0-0.0-0.1-1.2-0.1-0.4-0.4-0.5-0.6
Total zone transitions, hab. session 21.21.65.52.12.1-2.1-2.11.41.31.22.41.10.90.80.80.50.40.40.3-0.8-0.5-0.3-0.3-0.4-1.3
Total locomotion distance, hab. session 23.85.07.92.31.3-1.6-1.32.72.72.71.02.82.72.72.72.62.62.62.51.41.92.12.12.01.1
Locomotion velocity, hab. session 23.95.27.92.10.9-1.3-0.92.62.62.60.62.82.82.72.82.72.72.72.71.62.22.42.42.21.5
Novel to familiar place preference ratio0.70.71.40.2-0.10.00.20.60.60.8-0.30.80.80.90.91.00.90.91.11.11.21.21.21.01.0
Novelty place preference0.40.51.1-0.1-0.40.30.40.30.40.5-0.50.50.60.70.60.80.70.70.90.91.01.01.00.81.0
Time in novel zone, NPP test0.40.51.00.1-0.20.10.30.40.50.6-0.40.60.60.70.70.80.80.70.90.91.01.01.00.80.9
Total zone transitions, NPP test0.40.51.71.31.1-1.1-1.10.80.80.81.30.70.60.60.50.50.30.30.3-0.3-0.20.00.0-0.1-0.6
Total locomotion distance, NPP test4.25.89.52.61.5-1.7-1.42.82.83.11.13.02.92.92.92.92.82.72.61.82.12.12.12.11.1
Locomotion velocity, NPP test3.44.87.52.31.1-1.4-1.12.52.52.70.82.72.62.72.72.72.62.52.51.62.12.12.12.11.2
Intraocular pressure0.50.72.40.30.6-0.4-0.6-0.3-0.3-0.80.8-0.5-0.6-0.6-0.6-0.6-0.7-0.8-1.0-1.6-0.9-1.2-1.2-1.0-1.1
Delta distance traveled before/after self-admin1.21.31.8-0.8-0.50.60.5-1.2-1.2-1.2-0.1-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.0-1.2-1.2-1.2-1.2-0.9
Delta ambulatory time before/after self-admin2.32.85.0-2.0-1.81.91.8-2.2-2.2-2.1-1.4-2.0-2.0-1.9-1.9-1.7-1.7-1.7-1.5-0.9-1.0-1.0-1.0-1.0-0.2
Parametrial fat weight0.51.24.0-1.0-0.80.90.8-1.3-1.3-1.7-0.6-1.2-1.2-1.2-1.2-1.1-1.1-1.1-1.0-2.0-1.1-0.8-0.8-0.9-0.5
Pavlov. Cond. lever latency0.60.81.6-0.10.3-0.1-0.4-0.7-0.8-0.30.6-0.8-1.0-1.0-1.1-1.0-1.1-1.2-1.2-0.0-1.0-1.2-1.2-1.3-1.1
Pavlov. Cond. magazine entry latency0.50.71.20.90.7-0.8-0.61.11.10.90.41.11.00.91.00.80.90.90.80.60.70.70.70.60.4
Pavlov. Cond. change in total contacts0.50.50.90.70.5-0.5-0.50.90.90.60.10.90.90.90.90.90.90.90.80.10.50.70.70.80.4
Pavlov. Cond. index score0.40.50.90.30.0-0.1-0.00.80.80.5-0.20.80.90.80.90.80.90.90.90.30.70.90.90.90.7
Pavlov. Cond. latency score0.81.01.80.3-0.20.00.20.90.90.7-0.51.01.21.11.21.11.31.31.30.61.11.31.31.31.2
Pavlov. Cond. lever contacts0.60.81.40.3-0.0-0.10.10.90.90.5-0.30.91.11.01.11.01.11.21.10.10.81.11.11.20.9
Pavlov. Cond. magazine entry number0.10.20.6-0.6-0.70.70.7-0.4-0.4-0.3-0.7-0.3-0.2-0.1-0.10.0-0.0-0.00.10.10.30.20.20.30.5
Pavlov. Cond. intertrial magazine entries0.20.31.70.60.7-0.6-0.70.20.2-0.40.70.00.10.0-0.0-0.1-0.1-0.1-0.4-1.3-0.8-0.6-0.6-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.40.20.0-0.1-0.00.60.50.3-0.20.50.60.60.60.50.60.70.60.20.40.60.60.60.5
Pavlov. Cond. response bias0.20.30.60.70.8-0.8-0.80.70.70.50.70.50.50.40.50.30.40.40.2-0.2-0.10.10.10.0-0.2
Pavlov. Cond. lever latency1.41.95.6-2.2-2.42.22.4-1.6-1.6-1.9-2.2-1.3-1.0-0.9-0.8-0.6-0.5-0.5-0.2-0.90.10.40.40.41.1
Pavlov. Cond. magazine entry latency0.40.52.40.30.1-0.2-0.00.60.61.10.00.70.60.70.70.70.70.70.71.51.00.60.60.60.6
Pavlov. Cond. change in total contacts0.60.92.81.41.7-1.6-1.70.90.91.31.60.70.40.30.30.10.10.0-0.30.7-0.3-0.7-0.7-0.6-1.1
Pavlov. Cond. index score0.81.13.31.61.8-1.7-1.81.21.21.51.70.90.70.60.60.40.30.30.00.8-0.0-0.4-0.4-0.4-0.9
Pavlov. Cond. latency score0.70.92.31.51.5-1.5-1.51.21.11.51.41.00.80.70.70.50.50.50.21.00.2-0.2-0.2-0.1-0.5
Pavlov. Cond. lever contacts1.41.95.12.12.3-2.2-2.21.71.61.92.11.41.11.00.90.70.70.60.30.90.0-0.3-0.3-0.2-0.9
Pavlov. Cond. magazine entry number0.30.41.1-0.9-1.00.91.0-0.6-0.6-1.0-1.0-0.6-0.3-0.3-0.3-0.2-0.1-0.1-0.0-1.0-0.20.20.20.20.4
Pavlov. Cond. intertrial magazine entries0.10.20.80.20.10.0-0.10.30.3-0.4-0.30.20.40.40.40.50.50.40.5-0.90.10.50.50.50.4
Pavlov. Cond. lever-magazine prob. diff.0.60.82.31.41.5-1.4-1.51.01.01.31.40.80.60.50.50.30.30.2-0.00.8-0.0-0.4-0.4-0.3-0.7
Pavlov. Cond. response bias1.42.05.32.22.3-2.2-2.31.71.62.02.11.41.11.00.90.70.70.60.31.10.1-0.3-0.3-0.3-1.0
Time in closed arm before self-admin0.71.01.7-1.1-1.01.11.0-1.3-1.3-1.1-0.8-1.3-1.2-1.2-1.1-1.0-1.0-1.0-1.0-0.2-0.7-0.7-0.7-0.7-0.1
Time in closed arm after self-admin2.52.74.4-1.9-1.51.51.4-2.0-2.0-2.1-1.1-2.0-1.9-1.9-1.9-1.7-1.7-1.7-1.6-1.4-1.3-1.3-1.3-1.3-0.5
Time in open arm before self-admin0.30.30.60.20.3-0.1-0.3-0.4-0.4-0.30.4-0.4-0.5-0.5-0.6-0.6-0.6-0.6-0.7-0.6-0.7-0.7-0.7-0.7-0.8
Time in open arm after self-admin2.32.55.11.91.2-1.2-1.21.81.82.30.81.91.81.81.81.71.71.71.61.71.31.31.31.30.6
Bone: periosteal estimation1.42.97.82.82.6-2.6-2.62.12.12.02.51.81.61.61.51.31.11.10.90.30.30.20.20.1-0.7
Bone: periosteal perimeter1.93.36.62.62.3-2.3-2.22.42.42.31.92.22.12.01.91.71.71.71.30.80.90.80.80.8-0.1
Bone: post-yield work0.40.51.5-0.7-1.11.01.1-0.3-0.30.0-1.20.00.10.10.20.40.40.30.71.00.90.90.90.71.2
Progressive ratio test 1 active lever presses1.01.24.11.72.0-1.9-2.01.31.20.71.90.70.70.70.60.30.30.3-0.1-0.8-0.7-0.5-0.5-0.4-1.1
Progressive ratio test 1 breakpoint1.11.34.41.82.1-2.0-2.11.31.30.71.90.80.80.70.60.30.30.3-0.1-0.8-0.7-0.5-0.5-0.4-1.2
Progressive ratio test 1 inactive lever presses0.60.92.41.61.2-1.2-1.11.31.21.11.01.11.11.11.00.90.90.90.60.30.40.30.30.5-0.1
Progressive ratio test 2 active lever presses0.40.51.41.21.0-1.0-0.90.90.90.70.80.80.80.80.70.60.60.60.4-0.10.10.20.20.3-0.2
Progressive ratio test 2 breakpoint0.50.51.61.31.1-1.0-1.01.00.90.70.90.80.80.80.70.60.60.60.4-0.20.10.20.20.2-0.2
Progressive ratio test 2 inactive lever presses1.93.15.42.31.7-1.9-1.72.32.22.31.32.12.12.12.11.91.81.91.51.21.01.11.11.20.3
Incentive Sensitization - Responses0.00.00.10.30.1-0.0-0.0-0.1-0.20.10.0-0.1-0.1-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2
Incentive Sensitization - Breakpoint0.00.00.00.1-0.10.10.1-0.2-0.20.0-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.0-0.0-0.00.1-0.1
Sum of active levers in priming session hrs 5-61.00.91.60.50.4-0.7-0.41.11.21.10.31.21.21.21.21.21.11.11.10.90.90.90.90.90.6
Progressive ratio2.13.310.4-2.8-3.23.13.2-2.2-2.2-1.6-2.8-1.6-1.4-1.2-1.1-0.7-0.7-0.6-0.20.50.60.60.60.71.6
Food seeking constrained by brief footshock2.22.73.91.10.2-0.4-0.11.51.61.7-0.21.91.81.91.91.91.92.02.01.81.91.91.92.01.5
Seeking ratio, punishment vs. effort2.63.88.52.92.8-2.8-2.72.72.62.22.32.32.11.91.91.61.61.51.20.50.60.50.50.4-0.5
Retroperitoneal fat weight0.10.41.4-0.4-0.90.80.9-0.2-0.1-0.2-1.20.10.10.20.20.50.40.40.70.61.00.90.90.61.1
Reaction time number correct0.30.61.50.70.3-0.3-0.20.80.80.80.20.90.90.90.91.00.90.90.90.71.20.80.80.90.8
Reaction time mean minus median0.20.51.6-0.9-1.11.21.1-0.5-0.5-0.1-1.3-0.2-0.2-0.1-0.00.10.20.20.51.10.80.80.80.71.1
Reaction time mean minus median AUC0.10.30.8-0.4-0.60.70.6-0.1-0.10.0-0.80.20.20.20.30.30.40.40.70.50.60.80.80.80.9
Reaction time num false alarms2.23.25.72.31.9-2.0-1.92.32.32.41.62.12.12.02.01.81.81.71.51.30.81.01.01.00.1
Reaction time num false alarms AUC1.32.03.81.91.8-1.8-1.81.81.81.91.71.61.51.51.41.21.21.21.00.90.40.50.50.5-0.3
Reaction time trials correct on left0.30.61.50.70.3-0.3-0.20.80.80.80.20.90.90.90.91.00.90.90.90.71.20.80.80.90.8
Reaction time trials on left0.40.71.60.80.3-0.3-0.30.80.80.90.20.90.91.01.01.01.00.90.90.71.20.90.90.90.8
Reaction time mean0.00.00.10.20.2-0.2-0.20.10.00.10.30.0-0.0-0.1-0.1-0.1-0.1-0.10.1-0.0-0.3-0.0-0.0-0.2-0.2
Reaction time mean AUC0.00.00.10.20.2-0.1-0.10.10.00.20.20.1-0.0-0.1-0.1-0.1-0.1-0.10.00.1-0.3-0.0-0.0-0.1-0.2
Median of all reaction times0.10.10.40.50.5-0.5-0.50.30.20.20.60.20.10.00.0-0.1-0.1-0.10.1-0.3-0.4-0.1-0.1-0.3-0.5
Reaction time omissions0.50.81.61.01.0-1.0-1.01.21.21.00.71.11.10.90.90.70.90.90.90.50.60.70.70.60.1
Reaction time false alarm rate0.71.02.11.31.4-1.4-1.31.31.31.41.31.11.11.01.00.70.80.80.60.5-0.20.20.20.2-0.5
Reaction time premature initiation rate0.20.31.00.40.6-0.6-0.6-0.1-0.10.30.8-0.2-0.3-0.2-0.3-0.2-0.5-0.5-0.5-0.1-0.7-0.6-0.6-0.7-1.0
Reaction time premature initiations0.00.10.40.50.4-0.4-0.40.10.10.50.60.20.10.20.10.20.0-0.00.10.30.1-0.0-0.0-0.1-0.3
Std. dev. reaction times0.00.10.20.40.5-0.4-0.50.10.10.30.50.1-0.0-0.0-0.1-0.1-0.1-0.1-0.00.2-0.2-0.2-0.2-0.2-0.4
Reaction time trials completed0.40.71.60.80.3-0.3-0.30.80.80.90.20.90.91.01.01.01.00.90.90.71.20.90.90.90.8
Reaction time trials AUC0.30.71.50.80.3-0.3-0.30.80.80.80.20.90.90.90.91.00.90.90.90.71.20.90.90.90.8
Run reversals in cocaine runway, females0.80.81.61.30.9-1.0-0.91.11.11.20.71.01.01.01.01.00.90.80.80.90.50.60.60.50.2
Run reversals in cocaine runway, males0.70.72.01.11.3-1.3-1.31.11.00.91.40.90.80.70.70.40.40.50.0-0.3-0.3-0.3-0.30.1-0.8
Latency to leave start box in cocaine runway0.60.72.0-1.4-1.41.31.4-1.0-1.0-1.0-1.1-0.9-0.8-0.8-0.7-0.6-0.5-0.5-0.4-0.3-0.2-0.1-0.10.00.4
Latency to leave start box in cocaine runway, F2.63.05.7-2.4-2.12.12.1-2.2-2.2-2.2-1.6-2.0-2.0-2.0-1.9-1.7-1.6-1.6-1.5-1.0-1.0-1.0-1.0-0.8-0.1
Latency to leave start box in cocaine runway, M0.50.50.70.70.5-0.5-0.50.80.90.80.40.80.80.90.80.90.80.80.70.30.60.60.60.60.3
Std. dev. time between licks in bursts0.30.51.51.11.2-1.2-1.20.80.80.51.00.50.50.50.40.40.30.30.1-0.5-0.3-0.2-0.2-0.2-0.7
Total sessions with >9 infusions0.20.20.8-0.10.4-0.3-0.4-0.1-0.1-0.50.4-0.4-0.3-0.3-0.4-0.5-0.4-0.4-0.7-0.9-0.8-0.7-0.7-0.5-0.7
Short access day 1 total inactive lever presses0.60.82.10.50.2-0.3-0.20.90.91.30.11.01.01.11.01.01.01.01.01.50.80.90.90.90.7
Short access day 10 total inactive lever presses0.20.62.50.1-0.60.50.60.10.10.9-0.70.40.40.50.50.70.60.60.81.61.01.01.00.90.9
Short access day 1 total infusions0.30.30.70.30.2-0.4-0.20.70.70.60.20.60.80.80.80.80.80.80.60.20.40.50.50.70.4
Short access day 10 total infusions0.10.10.60.00.2-0.2-0.2-0.2-0.1-0.40.3-0.3-0.2-0.2-0.2-0.2-0.3-0.3-0.5-0.7-0.7-0.5-0.5-0.3-0.4
Short access total infusions0.10.10.30.30.5-0.6-0.50.30.4-0.00.50.10.20.20.20.10.10.1-0.2-0.5-0.5-0.3-0.3-0.1-0.3
Short access day 1 locomotion0.50.61.00.30.0-0.2-0.00.70.80.6-0.00.80.91.01.01.01.01.00.90.50.70.90.91.00.7
Short access day 10 total locomotion0.40.71.31.10.9-1.0-0.91.11.11.00.81.11.01.01.00.90.90.90.80.20.40.50.50.50.1
Short access total locomotion0.60.71.40.90.8-0.9-0.81.21.20.90.61.01.11.11.00.90.91.00.80.50.40.60.60.70.2
One hour access (0.3 mA shock)0.20.20.70.80.7-0.7-0.70.40.40.30.80.30.30.30.30.20.10.2-0.1-0.5-0.4-0.2-0.20.0-0.5
Compulsive drug intake0.10.10.3-0.2-0.50.40.5-0.2-0.20.1-0.3-0.1-0.00.00.00.10.10.10.10.20.30.20.20.40.2
One hour access (shock baseline)0.10.20.50.50.6-0.5-0.60.20.1-0.10.70.0-0.0-0.0-0.0-0.2-0.2-0.1-0.4-0.7-0.7-0.5-0.5-0.3-0.6
Social response proportion0.60.71.20.70.4-0.6-0.41.11.10.80.11.11.11.01.00.91.01.01.00.30.70.80.80.90.5
Social responses0.60.82.41.41.5-1.5-1.51.11.00.81.50.80.70.50.50.20.30.30.1-0.3-0.4-0.3-0.3-0.4-0.8
Social time0.00.00.10.00.3-0.3-0.30.20.20.00.20.10.1-0.1-0.0-0.2-0.0-0.00.0-0.1-0.1-0.1-0.1-0.2-0.1
Soleus weight0.51.42.31.41.0-1.1-1.01.41.51.20.91.31.41.51.41.51.31.31.2-0.20.80.90.90.90.4
Bone: stiffness0.91.42.81.71.5-1.6-1.51.71.61.31.31.41.41.31.31.11.11.10.80.10.50.50.50.5-0.2
Tibialis anterior weight0.62.17.42.22.6-2.5-2.61.51.50.92.70.90.90.80.70.40.30.3-0.0-1.4-0.6-0.6-0.6-0.7-1.5
Time to tail flick, vehicle, before self-admin0.90.91.9-0.0-0.60.40.60.40.40.8-0.70.70.80.90.91.11.01.01.21.41.31.31.31.31.3
Time to tail flick, vehicle, after self-admin0.50.71.8-1.3-0.90.80.9-1.1-1.0-1.1-0.4-1.1-1.0-0.9-0.9-0.7-0.8-0.8-0.7-0.6-0.5-0.5-0.5-0.5-0.1
Time to tail flick, test, before self-admin0.91.02.21.01.0-0.7-1.0-0.3-0.3-0.41.1-0.5-0.7-0.7-0.8-0.9-0.9-1.0-1.1-1.1-1.3-1.3-1.3-1.3-1.5
Time to tail flick, test, after self-admin0.50.61.5-0.7-0.90.60.90.10.20.1-0.90.40.50.40.50.60.70.70.80.91.01.01.01.01.2
Delta time to tail flick, vehicle, before/after SA0.70.71.80.30.9-0.8-0.90.00.0-0.51.1-0.4-0.4-0.5-0.5-0.7-0.7-0.7-0.9-1.3-1.1-1.1-1.1-1.1-1.2
Delta time to tail flick, test, before/after SA1.61.73.6-0.7-1.00.71.00.60.70.7-1.20.91.11.11.21.31.41.41.51.51.81.81.81.81.9
Tibia length2.15.815.02.13.3-2.9-3.30.30.20.03.9-0.5-0.9-1.1-1.2-1.7-1.8-1.8-2.4-2.5-3.0-3.1-3.1-3.0-3.9
Ambulatory time before self-admin1.32.05.21.92.3-2.3-2.31.91.81.42.11.51.41.31.21.00.90.90.6-0.20.00.00.00.0-0.8
Ambulatory time after self-admin0.70.81.91.01.3-1.1-1.30.20.2-0.11.3-0.1-0.2-0.3-0.4-0.5-0.6-0.6-0.8-1.0-1.1-1.1-1.1-1.1-1.4
Bone: tissue strength0.70.71.40.70.4-0.5-0.30.90.91.20.21.01.01.01.01.01.01.00.81.20.80.70.70.80.6
Total heroin consumption1.11.23.21.31.0-1.2-1.01.41.41.80.91.41.31.21.31.01.11.10.91.30.70.70.70.70.1
Bone: trabecular number1.93.16.72.62.5-2.5-2.52.42.31.82.02.01.91.91.81.61.41.41.10.10.60.50.50.5-0.3
Bone: trabecular spacing0.30.41.1-1.1-1.01.01.0-0.8-0.9-0.3-0.9-0.7-0.7-0.6-0.6-0.6-0.5-0.4-0.30.8-0.0-0.1-0.1-0.10.3
Bone: trabecular thickness0.60.71.51.21.0-1.1-1.01.21.20.50.81.01.00.90.90.70.80.80.6-0.70.10.40.40.4-0.1
Bone: trabecular tissue density0.60.92.11.21.2-1.3-1.21.41.41.10.71.11.21.01.00.70.90.90.60.20.10.30.30.4-0.2
Water consumed over 24 hours0.10.20.30.00.3-0.1-0.3-0.3-0.3-0.40.2-0.4-0.4-0.4-0.4-0.4-0.5-0.5-0.5-0.3-0.6-0.5-0.5-0.5-0.4
Number of responses in last shaping day0.20.20.60.70.6-0.6-0.60.50.50.50.80.40.40.40.40.30.30.30.2-0.1-0.10.10.10.0-0.2