Mei1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Mei1 0.18 0.1 1.1e-06 0.13 0.09 0.1 0.11 1.2e-07 1.1e-05 5.1e-06 1.2e-06
2 BLA gene expression Mei1 0.55 0.11 0.0e+00 0.5 0.5 0.49 0.5 1.1e-30 1.0e-30 1.4e-29 2.6e-30
3 PL mRNA stability Mei1 0.05 0.03 1.1e-06 0.03 0.04 0.03 0.04 2.0e-04 7.2e-05 1.6e-04 4.6e-05
4 Brain gene expression Mei1 0.75 0.08 0.0e+00 0.72 0.72 0.72 0.72 4.5e-95 2.3e-94 7.6e-96 9.6e-97
5 Brain isoform ratio XM_039079284.1 0.2 0.12 4.6e-10 0.1 0.09 0.1 0.1 1.2e-09 7.7e-09 3.8e-09 1.9e-09
6 PL gene expression Mei1 0.35 0.11 0.0e+00 0.41 0.41 0.41 0.42 6.4e-48 5.7e-48 6.4e-48 1.6e-50
7 Brain intron excision ratio chr7_113646742_113648134 0.16 0.07 0.0e+00 0.19 0.19 0.19 0.19 2.4e-17 5.1e-17 2.1e-17 1.1e-17
8 PL alternative TSS NM_001130555.1 0.04 0.02 2.8e-05 0.04 0.04 0.04 0.04 2.0e-05 8.1e-05 5.3e-05 6.4e-05
9 OFC gene expression Mei1 0.62 0.12 2.2e-14 0.31 0.32 0.29 0.34 3.3e-08 1.6e-08 1.1e-07 7.9e-09
10 Brain alternative TSS NM_001130555.1 0.23 0.15 1.9e-10 0.11 0.07 0.09 0.11 2.0e-10 4.9e-07 1.5e-08 4.1e-10
11 Brain alternative TSS XM_039079284.1 0.22 0.15 2.9e-10 0.11 0.07 0.09 0.1 4.4e-10 4.2e-07 2.3e-08 7.1e-10
12 Brain isoform ratio NM_001130555.1 0.2 0.12 3.8e-10 0.11 0.08 0.1 0.1 3.8e-10 7.4e-08 2.9e-09 1.1e-09
13 Brain intron excision ratio chr7_113642764_113643317 0.18 0.08 0.0e+00 0.17 0.18 0.16 0.17 1.0e-15 2.6e-16 4.1e-15 6.4e-16
14 NAcc gene expression Mei1 0.08 0.04 2.9e-12 0.09 0.1 0.06 0.1 4.6e-11 9.5e-12 6.0e-08 8.6e-12
15 IL gene expression Mei1 0.35 0.15 3.5e-03 0.04 0.1 0.1 0.1 4.5e-02 2.8e-03 2.5e-03 2.3e-03
16 OFC alternative TSS NM_001130555.1 0.18 0.11 3.8e-03 0.03 0.04 0.02 0.01 5.6e-02 4.3e-02 1.2e-01 1.5e-01
17 OFC isoform ratio NM_001130555.1 0.17 0.09 1.7e-03 0.06 0.07 -0 0.06 1.6e-02 7.6e-03 4.4e-01 1.9e-02
18 OFC isoform ratio XM_039079284.1 0.19 0.1 5.7e-04 0.08 0.1 0.01 0.07 6.4e-03 2.1e-03 1.6e-01 9.2e-03
19 OFC alternative TSS XM_039079284.1 0.17 0.1 4.0e-03 0.03 0.04 0.01 0 7.5e-02 3.8e-02 2.0e-01 3.0e-01
20 PL isoform ratio NM_001130555.1 0.04 0.03 5.4e-05 0.02 0.03 0.02 0.02 5.4e-03 2.6e-04 2.6e-03 1.2e-03
21 PL isoform ratio XM_039079284.1 0.04 0.02 5.1e-05 0.02 0.03 0.02 0.02 4.7e-03 1.8e-04 3.2e-03 1.2e-03
22 PL alternative TSS XM_039079284.1 0.04 0.03 2.5e-05 0.04 0.03 0.04 0.03 5.0e-05 1.2e-04 4.2e-05 1.3e-04
23 pVTA mRNA stability Mei1 0.26 0.15 8.0e-04 0.03 0.01 0.03 0.04 2.6e-02 8.7e-02 2.4e-02 8.4e-03
24 Brain mRNA stability Mei1 0.07 0.04 9.8e-05 0.06 0.05 0.05 0.05 2.5e-06 4.3e-05 1.7e-05 1.2e-05
25 BLA alternative TSS NM_001130555.1 0.07 0.05 4.2e-03 0.01 0.03 0.05 0.01 1.5e-01 7.9e-03 8.1e-04 6.6e-02
26 BLA alternative TSS XM_039079284.1 0.06 0.05 4.1e-03 0.01 0.03 0.05 0.01 1.5e-01 7.6e-03 8.5e-04 6.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.30.51.0-0.70.51.00.80.80.8-0.4-0.60.9-0.80.8-0.80.70.7-0.60.70.7-0.7-0.70.5-0.50.80.60.2-0.60.6
Area under the delay curve0.20.22.5-0.80.80.20.30.20.2-0.8-0.40.3-0.20.2-0.20.40.31.60.30.3-0.3-0.20.3-0.3-0.0-0.0-0.40.5-0.5
BMI with tail1.55.08.42.0-2.4-1.5-2.5-2.5-2.52.72.0-2.42.5-2.52.5-2.9-2.7-2.1-2.7-2.62.62.6-2.22.3-1.60.4-1.90.4-0.4
BMI without tail0.20.44.70.6-0.60.1-0.2-0.2-0.20.6-0.00.00.2-0.20.2-0.8-0.4-2.2-0.4-0.30.30.30.0-0.00.60.90.0-0.80.8
Body weight1.56.29.52.5-2.8-2.8-2.7-2.7-2.73.13.0-2.62.6-2.62.6-2.7-2.7-2.1-2.7-2.72.62.6-2.32.3-2.3-1.2-1.01.7-1.7
Weight adjusted by age0.20.31.30.3-0.2-1.00.10.20.2-0.40.1-0.1-0.10.1-0.10.50.40.10.30.3-0.3-0.40.3-0.3-0.0-1.11.10.9-0.9
Bone surface0.20.41.90.10.0-0.00.50.60.6-0.7-0.50.7-0.50.5-0.51.20.70.10.90.7-0.7-0.90.2-0.30.3-0.81.40.1-0.1
Bone volume0.10.10.50.0-0.10.00.20.20.2-0.2-0.10.4-0.20.2-0.20.50.2-0.50.40.3-0.3-0.40.1-0.10.2-0.30.7-0.20.2
Breakpoint value in progressive ratio session0.10.11.40.10.00.50.10.10.1-0.1-0.40.3-0.10.1-0.1-0.10.0-0.5-0.0-0.00.00.1-0.10.10.31.2-0.5-0.20.2
Number of licking bursts0.40.51.5-0.40.90.50.70.70.7-1.2-0.90.7-0.70.7-0.71.00.71.00.70.7-0.7-0.70.6-0.60.6-0.10.40.5-0.5
Context. condit. distance diff. score5.87.09.82.8-3.0-3.1-3.1-3.1-3.12.92.9-3.13.1-3.13.1-2.9-2.9-2.0-2.8-2.72.72.7-2.22.2-2.2-2.0-0.41.0-1.0
Locomotion velocity, session 10.40.43.40.5-0.2-0.80.10.10.1-0.6-0.00.2-0.10.1-0.11.00.41.10.50.4-0.3-0.5-0.0-0.1-0.3-1.81.60.3-0.3
Locomotion distance, session 12.63.47.1-1.52.01.21.91.91.9-2.4-1.71.9-1.91.9-1.92.52.12.72.12.0-2.0-2.11.7-1.71.1-0.71.6-0.80.8
Locomotion velocity, session 20.20.30.70.4-0.8-0.9-0.7-0.7-0.70.50.4-0.30.8-0.80.8-0.2-0.6-0.3-0.2-0.30.30.2-0.40.4-0.3-0.40.60.1-0.1
Locomotion distance, session 22.23.16.3-1.92.12.22.01.91.9-2.2-2.02.0-1.91.9-1.92.21.82.51.81.7-1.7-1.71.1-1.11.01.1-0.1-0.60.6
Locomotion velocity, session 30.20.32.00.3-0.5-1.0-0.4-0.4-0.40.30.5-0.20.5-0.50.50.1-0.20.20.0-0.00.0-0.10.0-0.0-0.3-1.41.1-0.40.4
Locomotion distance, session 31.61.74.5-1.31.50.71.31.31.3-1.6-0.91.3-1.21.2-1.21.61.42.11.31.4-1.4-1.41.5-1.50.7-1.01.4-0.60.6
Stereotopy head waving bouts, day 30.80.91.90.9-1.4-1.2-1.1-1.0-1.01.11.1-1.01.0-1.01.0-0.6-0.9-1.0-0.7-0.90.90.7-1.11.1-1.0-0.60.10.5-0.5
Stereotopy head waving duration, day 33.23.97.62.3-2.8-2.6-2.3-2.3-2.32.32.0-2.12.2-2.22.2-1.8-2.1-2.5-1.7-1.81.81.6-1.81.8-1.3-1.10.30.8-0.8
Locomotion velocity, session 70.10.10.5-0.2-0.1-0.5-0.3-0.4-0.40.40.7-0.30.3-0.30.3-0.2-0.40.4-0.2-0.10.10.10.1-0.1-0.4-0.50.3-0.20.2
Locomotion distance, session 70.30.33.4-1.30.90.70.30.20.2-0.20.20.2-0.20.2-0.20.10.01.80.10.1-0.2-0.00.2-0.1-0.50.5-1.0-0.10.1
Stereotopy head waving bouts, day 72.12.46.32.2-2.4-2.5-1.7-1.6-1.61.61.8-1.61.5-1.51.5-0.9-1.2-1.7-1.0-1.11.10.9-1.11.1-1.2-2.41.7-0.20.2
Stereotopy head waving duration, day 71.51.85.11.8-2.1-2.3-1.4-1.3-1.31.71.5-1.41.3-1.31.3-1.0-1.1-2.1-0.9-1.00.90.8-0.70.7-0.8-1.81.6-0.40.4
Locomotion velocity, session 82.42.96.72.6-2.0-1.8-1.9-1.9-1.91.31.4-1.82.0-2.02.0-1.4-1.6-0.5-1.7-1.71.81.7-1.81.8-1.6-1.3-0.21.3-1.3
Locomotion distance, session 80.71.11.81.1-1.3-1.2-1.3-1.3-1.31.00.8-1.31.3-1.31.3-1.1-1.1-0.7-1.0-1.01.01.0-0.80.8-0.7-0.90.0-0.00.1
Degree of sensitization distance3.23.25.60.9-1.6-0.9-1.9-1.9-1.92.21.7-1.81.9-1.91.9-2.3-2.1-1.5-2.0-2.01.92.0-1.81.9-1.51.2-2.41.0-1.0
Degree of sensitization stereotypy1.31.45.71.7-1.7-2.1-1.2-1.1-1.11.11.4-1.11.0-1.01.0-0.6-0.8-1.2-0.7-0.80.80.6-0.60.6-0.9-2.41.7-0.20.2
Conditioned locomotion0.50.61.20.2-0.7-1.0-0.9-1.0-1.00.80.7-1.01.1-1.11.1-1.0-0.7-0.8-0.7-0.60.60.6-0.10.1-0.2-1.10.3-0.80.8
Cocaine response after cond. corrected0.10.11.40.2-0.2-0.2-0.1-0.1-0.10.20.3-0.20.2-0.20.2-0.1-0.2-1.2-0.1-0.00.00.00.1-0.10.2-0.20.3-0.30.3
Cocaine response after cond. not corrected0.10.22.40.3-0.3-0.3-0.2-0.2-0.20.20.1-0.10.3-0.30.3-0.2-0.2-1.60.00.0-0.1-0.10.2-0.20.50.00.5-0.50.5
Cocaine response before conditioning0.10.10.5-0.20.10.00.0-0.0-0.0-0.2-0.70.2-0.00.0-0.0-0.00.0-0.10.30.3-0.3-0.30.4-0.40.60.70.1-0.10.1
Saline control response0.30.32.50.9-0.6-1.0-0.5-0.5-0.4-0.0-0.4-0.20.5-0.50.5-0.1-0.1-1.60.10.1-0.1-0.20.3-0.30.8-0.71.1-0.10.1
Bone: connectivity density0.10.20.5-0.50.30.70.50.60.6-0.2-0.30.6-0.50.5-0.50.60.5-0.40.50.4-0.4-0.40.1-0.20.30.30.1-0.20.1
Bone: cortical apparent density0.60.81.5-1.21.11.00.90.90.9-1.2-1.00.9-0.90.9-0.91.10.91.20.90.9-0.9-0.90.6-0.60.60.10.1-0.30.3
Bone: cortical area1.52.23.71.9-1.9-1.6-1.7-1.7-1.71.61.5-1.61.6-1.61.6-1.5-1.6-1.1-1.5-1.61.61.5-1.61.5-1.3-0.9-0.30.8-0.8
Bone: cortical porosity0.70.85.70.8-1.0-0.8-0.9-0.9-0.91.10.7-0.71.0-1.01.0-1.0-0.8-2.4-0.7-0.70.60.6-0.40.40.20.2-0.0-0.20.2
Bone: cortical porosity1.41.57.21.4-1.6-1.2-1.4-1.3-1.31.61.2-1.11.4-1.41.4-1.4-1.2-2.7-1.1-1.11.11.0-0.90.9-0.3-0.1-0.0-0.00.0
Bone: cortical thickness0.40.72.80.7-0.40.1-0.6-0.6-0.60.60.6-0.50.7-0.70.7-0.8-0.80.1-0.9-0.91.01.0-1.11.1-0.80.6-1.71.0-1.0
Bone: cortical thickness0.70.82.80.6-0.3-0.1-0.7-0.7-0.70.40.6-0.70.8-0.80.8-0.9-0.90.3-1.1-1.01.11.2-1.01.1-0.90.3-1.71.3-1.3
Bone: cortical tissue density0.50.71.6-1.21.11.00.90.90.9-1.2-0.90.9-0.90.9-0.91.10.91.30.90.8-0.8-0.80.6-0.60.50.10.0-0.30.3
Condit. Reinf. active minus inactive responses0.20.22.7-0.80.40.40.30.20.2-0.3-0.40.3-0.20.2-0.20.50.11.60.40.3-0.2-0.3-0.10.1-0.20.5-0.50.2-0.2
Condit. Reinf. active-inactive response ratio0.30.30.70.3-0.6-0.7-0.6-0.6-0.60.40.5-0.60.5-0.50.5-0.2-0.50.9-0.3-0.40.40.3-0.70.6-0.8-0.5-0.10.2-0.2
Condit. Reinf. active responses1.01.23.0-1.71.31.21.11.01.0-1.1-1.61.2-1.01.0-1.01.00.91.51.11.1-1.1-1.10.8-0.80.91.6-0.4-0.10.1
Condit. Reinf. inactive responses2.22.65.0-2.21.91.81.81.71.7-1.6-2.21.8-1.61.6-1.61.31.60.81.61.6-1.6-1.61.6-1.61.92.0-0.1-0.50.5
Incentive salience index mean0.40.53.2-1.30.90.80.60.50.5-0.6-0.80.6-0.40.4-0.40.60.31.80.60.5-0.5-0.50.2-0.20.11.0-0.80.2-0.2
Condit. Reinf. lever presses0.60.82.9-1.71.10.90.80.70.7-0.9-1.30.9-0.60.6-0.60.70.61.10.90.9-0.9-0.90.7-0.70.91.2-0.4-0.20.2
Condit. Reinf. active minus inactive responses0.30.45.20.30.10.40.10.10.1-0.40.1-0.10.0-0.00.00.40.02.3-0.1-0.30.30.2-0.90.8-1.1-0.2-0.80.5-0.5
Condit. Reinf. active-inactive response ratio0.50.54.40.4-0.20.4-0.1-0.1-0.10.10.4-0.20.1-0.10.10.2-0.22.1-0.2-0.40.50.4-1.11.1-1.50.2-1.10.6-0.7
Condit. Reinf. active responses0.50.82.41.1-0.8-0.7-0.8-0.8-0.80.20.6-0.90.8-0.80.8-0.2-0.61.6-0.6-0.80.90.7-1.21.2-1.4-1.0-0.40.8-0.8
Condit. Reinf. inactive responses0.81.02.80.9-1.0-1.7-1.2-1.2-1.20.60.8-1.21.2-1.21.2-0.8-1.00.2-0.9-1.00.90.9-0.90.9-0.9-1.40.01.0-0.9
Condit. Reinf. lever presses0.40.55.4-0.10.40.80.70.70.7-0.6-0.60.4-0.60.6-0.60.80.72.30.60.5-0.4-0.5-0.10.1-0.50.7-0.20.1-0.1
Condit. Reinf. lever reinforcers received0.30.53.30.7-0.5-0.4-0.5-0.5-0.50.00.3-0.60.5-0.50.50.0-0.41.8-0.4-0.50.60.4-1.11.0-1.3-0.6-0.40.5-0.5
Conditioned reinforcement - actives0.40.42.20.5-0.3-1.1-0.6-0.7-0.7-0.00.2-0.70.6-0.60.6-0.2-0.50.8-0.5-0.50.50.5-0.50.5-0.5-1.5-0.10.8-0.8
Conditioned reinforcement - inactives0.20.32.1-0.10.20.10.0-0.00.0-0.4-0.7-0.1-0.00.0-0.0-0.0-0.00.4-0.2-0.20.20.2-0.40.40.20.5-0.91.4-1.4
Conditioned locomotion1.92.33.21.4-1.5-1.4-1.7-1.8-1.81.51.3-1.71.8-1.81.8-1.5-1.7-0.1-1.7-1.71.71.7-1.71.7-1.5-0.8-1.20.8-0.8
Patch foraging indifference point 0 sec0.30.41.7-0.00.41.00.70.70.7-0.7-1.20.6-0.70.7-0.70.60.60.10.60.5-0.5-0.60.1-0.20.71.3-0.1-0.10.1
Patch foraging indifference point AUC0.30.43.6-0.30.60.40.40.40.4-0.9-0.20.3-0.50.5-0.51.00.51.90.50.4-0.3-0.4-0.0-0.0-0.4-0.90.3-0.20.2
Delay disc. indifference point, 0s delay1.21.33.70.8-1.1-0.8-1.3-1.3-1.31.20.8-1.21.3-1.31.3-1.6-1.3-1.9-1.2-1.21.11.2-0.80.8-0.30.7-1.00.4-0.4
Delay disc. indifference point, 16s delay1.61.63.9-1.51.71.21.41.41.4-1.4-1.01.4-1.31.3-1.31.51.42.01.31.3-1.3-1.31.1-1.10.60.20.4-0.50.5
Delay disc. indifference point, 2s delay0.20.20.7-0.30.1-0.4-0.5-0.6-0.60.00.2-0.40.6-0.60.6-0.6-0.60.2-0.5-0.40.40.5-0.20.3-0.2-0.1-0.80.7-0.7
Delay disc. indifference point, 24s delay0.50.53.1-0.50.7-0.20.50.40.4-0.70.30.4-0.50.5-0.51.20.61.80.60.6-0.5-0.60.3-0.3-0.6-1.70.90.4-0.4
Delay disc. indifference point, 4s delay0.30.32.00.30.00.0-0.2-0.3-0.3-0.3-0.3-0.10.3-0.30.3-0.1-0.30.8-0.3-0.40.40.4-0.70.7-0.40.5-1.11.4-1.4
Delay disc. indifference point, 8s delay0.80.84.2-1.41.40.90.90.70.7-1.1-0.90.9-0.70.7-0.70.80.82.00.80.8-0.9-0.80.9-0.80.50.2-0.1-0.20.2
Indifference point function ln k0.91.32.51.1-1.5-1.1-1.2-1.2-1.21.61.4-1.11.3-1.31.3-1.4-1.2-1.5-1.2-1.21.11.1-1.01.0-0.9-0.3-0.20.4-0.4
Indifference point function log k0.91.32.51.1-1.5-1.1-1.2-1.2-1.21.61.4-1.11.3-1.31.3-1.4-1.2-1.5-1.2-1.21.11.1-1.01.0-0.9-0.3-0.20.4-0.4
Patch foraging total patch changes 0 sec0.40.61.9-0.10.51.00.90.90.9-0.8-1.30.8-0.90.9-0.90.80.80.20.80.7-0.6-0.70.3-0.30.81.4-0.0-0.00.0
Patch foraging total patch changes 12 sec0.10.10.60.3-0.10.2-0.1-0.1-0.1-0.2-0.2-0.20.0-0.00.00.4-0.10.80.1-0.10.1-0.0-0.50.5-0.30.2-0.40.3-0.3
Patch foraging total patch changes 18 sec0.10.21.40.20.20.60.40.30.3-0.5-0.70.2-0.30.3-0.30.40.31.20.20.1-0.0-0.1-0.40.4-0.00.6-0.4-0.10.0
Patch foraging total patch changes 24 sec0.30.30.7-0.20.60.60.60.60.6-0.8-0.80.5-0.60.6-0.60.80.60.50.60.6-0.5-0.60.3-0.30.60.20.4-0.60.6
Patch foraging total patch changes 6 sec0.20.31.10.70.20.40.30.40.4-0.8-1.00.4-0.50.5-0.50.70.30.50.40.3-0.2-0.3-0.30.30.20.8-0.11.0-1.0
Patch foraging time to switch 0 sec0.10.21.7-0.80.0-0.10.10.10.10.50.00.2-0.10.1-0.1-0.2-0.0-1.30.30.3-0.4-0.40.6-0.50.80.80.1-0.60.6
Patch foraging water rate 0 sec0.10.20.80.90.00.90.40.40.4-0.5-0.60.4-0.30.3-0.30.40.4-0.30.10.10.0-0.0-0.30.30.00.7-0.10.4-0.4
Patch foraging water rate 12 sec0.40.61.30.00.40.80.70.90.9-0.8-1.11.0-0.90.9-0.90.80.90.10.70.7-0.7-0.70.5-0.50.70.20.7-1.11.1
Patch foraging water rate 18 sec1.31.73.4-0.41.01.31.31.51.5-1.5-1.61.8-1.61.6-1.61.81.50.81.51.4-1.4-1.50.9-0.90.80.41.0-0.70.7
Patch foraging water rate 24 sec0.10.11.31.1-0.60.40.00.20.20.1-0.10.1-0.00.0-0.00.10.0-0.2-0.1-0.30.30.2-0.80.7-0.40.3-0.1-0.10.1
Patch foraging water rate 6 sec1.01.42.9-0.60.80.51.31.41.4-1.4-1.31.3-1.21.2-1.21.61.50.51.41.3-1.3-1.41.0-1.11.0-0.31.7-0.50.5
Seeking ratio, delayed vs. immediate footshock3.43.97.3-2.62.32.72.12.02.0-1.9-1.82.1-2.02.0-2.01.81.92.01.91.9-1.9-1.91.6-1.61.31.90.3-2.32.3
Distance traveled before self-admin0.30.33.0-0.70.40.6-0.2-0.3-0.30.2-0.1-0.30.3-0.30.3-0.7-0.50.6-0.5-0.40.40.5-0.30.4-0.11.4-1.70.5-0.5
Distance traveled after self-admin0.20.20.70.5-0.4-0.2-0.4-0.4-0.4-0.0-0.3-0.30.4-0.40.4-0.4-0.4-0.4-0.5-0.50.60.5-0.80.8-0.20.3-0.70.7-0.7
Extensor digitorum longus weight0.20.62.10.10.40.70.70.80.8-0.6-1.10.9-0.70.7-0.70.40.8-1.50.70.7-0.7-0.70.8-0.81.40.90.6-0.40.4
Bone: elastic displacement0.20.32.01.1-0.6-0.9-0.1-0.0-0.0-0.10.10.1-0.10.1-0.10.30.1-0.80.10.1-0.0-0.10.0-0.10.1-1.11.40.6-0.6
Bone: elastic work2.12.66.72.6-2.3-1.8-1.7-1.6-1.61.91.7-1.51.6-1.61.6-1.6-1.6-2.0-1.6-1.61.71.5-1.71.6-1.3-0.6-0.01.2-1.2
Bone: endosteal estimation0.71.65.31.9-2.1-2.3-1.4-1.3-1.31.21.2-1.31.2-1.21.2-0.6-1.0-1.5-0.6-0.70.70.4-0.70.6-0.7-1.92.0-0.30.3
Bone: endosteal perimeter1.53.08.72.0-2.5-2.9-2.0-1.9-1.91.91.9-1.91.8-1.81.8-1.4-1.6-2.2-1.2-1.31.21.0-0.90.8-1.0-2.41.8-0.50.5
Epididymis fat weight2.66.110.51.9-2.7-3.2-2.9-2.9-2.92.93.1-3.02.8-2.82.8-2.8-2.7-1.6-2.6-2.52.42.5-1.81.9-2.2-2.5-0.30.4-0.3
Delta time in closed arm before/after self-admin1.61.52.40.7-0.9-1.1-1.5-1.5-1.51.00.9-1.61.5-1.51.5-1.4-1.40.3-1.5-1.41.41.5-1.31.3-1.1-0.6-1.40.5-0.5
Delta time in open arm before/after self-admin0.50.51.3-0.50.30.10.60.70.7-0.6-0.80.6-0.60.6-0.60.60.7-0.80.70.7-0.7-0.80.9-0.91.1-0.31.1-0.70.7
Diff in mean of infusions in LGA sessions0.40.41.5-0.81.00.60.70.60.6-0.60.10.6-0.60.6-0.60.70.61.20.50.5-0.5-0.50.4-0.4-0.10.4-0.31.1-1.1
Delay discount exponential model param0.30.33.00.8-0.9-0.2-0.4-0.2-0.20.90.5-0.40.3-0.30.3-0.5-0.4-1.7-0.4-0.40.40.3-0.30.3-0.00.10.3-0.60.6
Extinction: sum of active levers before priming0.10.10.30.10.1-0.1-0.1-0.2-0.20.0-0.30.00.1-0.10.1-0.1-0.20.1-0.1-0.10.10.2-0.10.10.20.5-0.40.6-0.6
Active lever presses in extinction session 60.30.20.60.5-0.4-0.4-0.5-0.5-0.50.40.2-0.30.5-0.50.5-0.6-0.5-0.8-0.5-0.50.50.5-0.50.5-0.10.5-0.60.6-0.6
Bone: final force1.62.75.71.7-1.6-1.0-1.6-1.6-1.61.72.0-1.61.6-1.61.6-1.4-1.70.4-1.7-1.81.81.7-2.12.1-2.4-0.3-1.61.4-1.4
Bone: final moment1.83.05.92.0-1.8-1.1-1.7-1.7-1.71.82.0-1.61.7-1.71.7-1.5-1.80.2-1.8-1.91.91.8-2.32.2-2.4-0.4-1.51.6-1.6
Food consumed during 24 hour testing period1.92.34.01.5-1.4-1.3-1.5-1.6-1.61.61.7-1.41.5-1.51.5-1.5-1.6-0.1-1.5-1.51.61.5-1.61.6-1.7-0.2-1.12.0-2.0
Glucose0.30.42.1-0.90.50.70.70.60.6-0.4-0.90.6-0.60.6-0.60.30.5-0.40.60.6-0.6-0.60.6-0.50.91.4-0.2-0.50.5
Heart weight3.24.57.22.4-2.4-1.7-2.3-2.3-2.22.31.2-2.12.1-2.12.1-2.7-2.3-2.5-2.5-2.42.42.5-2.22.2-1.10.5-1.91.7-1.7
Delay discount hyperbolic model param0.20.22.00.6-0.7-0.1-0.1-0.0-0.00.70.3-0.20.0-0.00.0-0.3-0.1-1.4-0.1-0.10.10.1-0.20.10.00.10.4-0.70.7
Intermittent access intake day 1-15 change0.40.40.8-0.50.70.60.80.80.8-0.8-0.90.6-0.70.7-0.70.60.80.70.50.5-0.5-0.50.4-0.40.60.50.4-0.30.3
Intermittent access intake escalation0.50.50.8-0.50.70.70.90.90.9-0.9-0.90.6-0.70.7-0.70.60.90.50.60.6-0.6-0.60.5-0.50.60.70.4-0.40.4
Intermittent access intake escalation 20.20.20.5-0.20.30.20.50.50.5-0.6-0.70.4-0.40.4-0.40.30.60.10.40.4-0.4-0.40.4-0.40.60.40.50.1-0.0
Intermitt. access day 1 inactive lever presses0.80.81.81.2-0.90.1-0.7-0.7-0.70.60.2-0.80.7-0.70.7-0.8-0.9-0.8-0.9-1.01.01.0-1.21.2-0.41.0-1.31.3-1.3
Intermitt. access day 15 inactive lever presses1.31.44.81.1-0.70.4-1.0-1.1-1.10.50.3-1.21.1-1.11.1-1.0-1.20.9-1.3-1.41.41.5-1.71.8-1.20.5-2.20.8-0.9
Intermitt. access escalation Index0.10.10.40.20.10.50.20.20.2-0.20.1-0.0-0.10.1-0.1-0.10.10.6-0.1-0.10.10.1-0.20.3-0.40.5-0.20.1-0.1
Intermittent access day 1 total infusions1.01.21.70.9-1.0-1.0-1.1-1.2-1.20.80.8-1.11.1-1.11.1-1.0-1.2-0.2-1.2-1.21.21.2-1.31.3-1.0-0.7-1.01.2-1.2
Intermittent access day 15 total infusions0.10.10.30.10.10.20.10.10.1-0.3-0.3-0.00.0-0.00.00.00.10.5-0.2-0.20.30.3-0.40.4-0.10.2-0.50.6-0.6
Intermittent access terminal intake (last 3 days)0.00.10.20.0-0.1-0.3-0.1-0.2-0.2-0.00.1-0.20.2-0.20.2-0.2-0.10.1-0.3-0.30.30.3-0.20.3-0.1-0.4-0.10.4-0.4
Intermittent access total infusions0.30.30.80.3-0.4-0.4-0.5-0.6-0.60.50.5-0.50.6-0.60.6-0.6-0.6-0.1-0.7-0.70.70.7-0.70.7-0.5-0.2-0.70.9-0.9
Intermittent access day 1 locomotion0.50.50.80.6-0.6-0.6-0.7-0.7-0.70.70.4-0.70.7-0.70.7-0.9-0.8-0.7-0.8-0.80.80.8-0.80.8-0.30.2-0.80.9-0.9
Intermittent access day 15 total locomotion0.10.10.60.4-0.3-0.4-0.2-0.2-0.20.50.3-0.30.2-0.20.2-0.2-0.2-0.7-0.4-0.40.40.4-0.50.5-0.2-0.3-0.20.6-0.6
Intermittent access total locomotion0.50.61.30.5-0.6-0.6-0.7-0.7-0.70.90.7-0.70.7-0.70.7-0.8-0.8-0.4-0.8-0.90.90.9-0.91.0-0.70.1-0.91.1-1.1
Intermittent access standard deviation0.70.71.40.6-0.8-0.4-0.8-0.8-0.80.90.6-0.90.9-0.90.9-1.2-0.9-0.7-1.1-1.11.11.1-1.01.0-0.50.5-1.1-0.10.1
Left kidney weight12.033.845.06.7-6.6-6.1-6.7-6.7-6.76.06.3-6.56.4-6.46.4-5.6-6.4-2.1-6.0-6.26.26.0-6.16.1-6.1-4.0-2.43.3-3.3
Right kidney weight13.437.649.36.9-6.8-6.4-7.0-7.0-7.06.26.5-6.86.8-6.86.8-6.0-6.7-2.3-6.5-6.66.66.4-6.46.4-6.2-3.8-2.84.0-4.0
Cocaine induced anxiety1.11.22.61.1-0.9-0.2-0.9-0.9-0.91.61.6-0.80.9-0.90.9-1.2-1.1-0.8-1.1-1.21.21.2-1.31.3-1.30.8-1.61.0-1.0
Post-drug Anxiety0.30.30.91.0-0.60.1-0.3-0.3-0.30.80.9-0.40.3-0.30.3-0.5-0.5-0.5-0.6-0.60.60.6-0.80.8-0.80.4-0.60.5-0.6
Baseline Anxiety1.31.42.3-1.11.10.71.21.21.2-1.5-1.41.1-1.21.2-1.21.31.31.11.31.3-1.3-1.31.4-1.41.2-0.31.4-0.60.6
Tail length0.20.61.0-0.20.50.10.90.90.9-0.6-0.40.9-0.90.9-0.90.70.9-0.70.80.9-0.9-0.91.0-1.00.80.01.00.1-0.1
Length with tail0.31.13.31.2-1.2-1.8-0.9-0.8-0.81.11.6-1.00.8-0.80.8-0.4-0.7-0.6-0.7-0.70.80.6-0.80.8-1.3-1.60.41.5-1.5
Length without tail1.12.55.51.2-1.5-1.8-1.6-1.6-1.61.62.2-1.81.5-1.51.5-0.8-1.40.7-1.3-1.51.51.4-1.91.8-2.3-1.7-0.71.5-1.5
Times rat made contact with spout1.01.24.21.0-0.7-1.0-1.0-1.0-1.00.70.9-0.91.1-1.11.1-0.9-1.0-0.4-1.1-1.11.11.2-1.11.1-1.0-0.4-1.02.0-2.1
Lifetime Intake1.01.12.40.7-0.8-0.5-1.0-1.1-1.10.90.9-1.01.1-1.11.1-1.1-1.10.0-1.3-1.31.31.3-1.31.3-1.1-0.0-1.61.0-1.0
Liver weight, left0.61.04.10.6-1.3-2.0-1.1-1.0-1.01.11.1-1.11.0-1.01.0-0.8-0.8-1.5-0.7-0.70.70.6-0.40.4-0.4-1.81.00.3-0.2
Liver weight, right1.83.08.01.3-2.0-2.8-2.0-2.0-2.02.12.3-2.12.1-2.12.1-1.9-1.8-1.7-1.6-1.51.41.4-0.80.8-1.1-2.10.70.1-0.1
Locomotor activity1.62.54.72.1-2.2-1.8-1.7-1.7-1.72.11.8-1.61.5-1.51.5-1.4-1.6-2.0-1.5-1.61.61.5-1.51.5-1.3-1.40.10.7-0.7
Locomotor testing distance0.00.00.1-0.10.10.00.10.10.10.1-0.00.4-0.20.2-0.20.30.1-0.40.20.2-0.2-0.20.1-0.10.1-0.10.1-0.20.1
Locomotor testing rearing1.42.13.91.2-1.5-2.0-1.6-1.7-1.71.71.5-1.51.6-1.61.6-1.7-1.6-1.9-1.5-1.51.41.5-1.01.1-0.8-1.0-0.50.9-0.9
Locomotion in novel chamber1.31.65.6-0.50.4-0.50.80.90.9-1.3-2.20.7-0.80.8-0.80.71.2-0.81.01.1-1.1-1.11.6-1.62.4-0.81.9-2.02.0
Locomotion in novel chamber post-restriction1.11.42.9-1.71.30.91.01.01.0-0.9-1.01.1-1.11.1-1.10.91.00.31.21.2-1.3-1.21.4-1.41.40.50.7-1.71.7
Fecal boli incidents, locomotor time 10.30.30.7-0.40.70.80.60.60.6-0.5-0.60.7-0.60.6-0.60.70.5-0.00.60.6-0.6-0.60.5-0.50.60.50.1-0.20.2
Change in fecal boli incidents, locomotor task0.60.65.40.5-0.5-1.0-0.3-0.3-0.30.10.9-0.50.4-0.40.40.2-0.11.7-0.3-0.30.40.3-0.40.4-1.3-2.30.90.1-0.1
Time >=10cm from walls, locomotor time 10.10.10.3-0.1-0.2-0.0-0.2-0.3-0.30.50.6-0.10.3-0.30.3-0.2-0.3-0.1-0.1-0.20.20.1-0.20.2-0.5-0.0-0.0-0.40.4
Bouts of movement, locomotor time 10.20.21.5-0.30.00.0-0.4-0.4-0.50.71.2-0.30.3-0.30.3-0.2-0.50.5-0.4-0.30.30.4-0.30.3-0.9-0.4-0.50.1-0.2
Total resting periods, locomotor time 10.20.20.9-0.60.30.4-0.2-0.3-0.30.61.0-0.00.1-0.10.1-0.2-0.40.8-0.2-0.20.20.3-0.20.2-0.80.3-0.90.2-0.2
Rest time, locomotor task time 10.60.73.6-0.5-0.00.3-0.7-0.9-0.91.00.9-0.60.7-0.70.7-1.0-1.10.4-0.9-0.80.80.9-0.60.7-0.81.0-1.9-0.10.1
Distance moved, locomotor task time 10.50.62.31.1-1.1-1.5-0.7-0.7-0.70.50.4-0.80.8-0.80.8-0.7-0.5-1.2-0.6-0.60.60.5-0.40.4-0.2-0.90.51.0-0.9
Vertical activity count, locomotor time 10.10.10.90.7-0.3-0.40.20.20.2-0.1-0.2-0.0-0.00.0-0.00.10.3-0.10.1-0.00.0-0.1-0.10.1-0.1-0.20.51.0-0.9
Time >=10cm from walls, locomotor time 20.20.20.7-0.60.30.20.30.30.3-0.3-0.30.4-0.20.2-0.20.20.3-0.00.40.4-0.4-0.40.5-0.50.50.00.4-0.80.8
Bouts of movement, locomotor time 20.50.52.1-0.0-0.20.1-0.5-0.6-0.60.80.5-0.50.8-0.80.8-0.9-0.8-0.6-0.8-0.80.80.9-0.70.7-0.30.7-1.40.8-0.8
Total resting periods, locomotor time 20.40.42.2-0.0-0.10.2-0.4-0.5-0.50.60.5-0.40.7-0.70.7-0.7-0.7-0.2-0.7-0.70.70.8-0.70.7-0.50.7-1.50.9-0.9
Rest time, locomotor task time 20.10.11.0-0.40.60.60.30.20.2-0.3-0.10.3-0.30.3-0.30.40.21.00.20.2-0.2-0.20.1-0.1-0.20.1-0.40.3-0.4
Distance moved, locomotor task time 20.80.92.50.8-1.2-1.6-1.1-1.1-1.10.80.6-1.01.2-1.21.2-1.3-1.0-1.5-1.0-0.90.90.9-0.50.5-0.1-0.6-0.10.4-0.3
Vertical activity count, locomotor time 20.30.41.00.8-0.9-0.9-0.6-0.6-0.60.60.2-0.60.7-0.70.7-0.7-0.5-1.0-0.6-0.60.60.5-0.40.4-0.0-0.50.2-0.00.1
Light reinforcement 10.40.87.60.4-0.6-0.3-0.4-0.4-0.4-0.2-0.4-0.40.3-0.30.30.1-0.1-0.90.10.0-0.0-0.20.1-0.10.6-1.01.2-2.72.8
Light reinforcement 20.81.03.60.3-1.0-0.7-1.2-1.2-1.21.10.9-1.11.2-1.21.2-1.1-1.1-0.7-0.8-0.80.80.7-0.50.6-0.5-0.5-0.2-1.91.9
Bone: marrow area0.81.85.72.0-2.2-2.4-1.5-1.4-1.41.21.2-1.41.3-1.31.3-0.6-1.0-1.6-0.6-0.80.80.5-0.80.7-0.7-2.02.0-0.20.3
Bone: maximum diameter3.86.911.93.3-3.5-3.4-3.1-3.0-3.02.82.7-2.92.9-2.92.9-2.5-2.8-2.1-2.6-2.72.72.5-2.62.5-2.3-2.0-0.11.3-1.3
Bone: maximum force2.84.87.02.6-2.4-1.7-2.3-2.3-2.32.32.5-2.32.3-2.32.3-2.1-2.4-0.7-2.3-2.42.42.4-2.62.6-2.5-0.7-1.51.4-1.4
Bone: maximum moment3.15.48.73.0-2.6-1.8-2.5-2.5-2.52.42.5-2.42.5-2.52.5-2.2-2.5-0.9-2.4-2.52.62.5-2.82.7-2.6-0.8-1.51.6-1.6
Mean time between licks in bursts0.40.61.0-0.81.00.70.90.90.9-0.7-0.90.8-0.80.8-0.80.40.90.40.60.7-0.8-0.61.0-1.00.90.8-0.00.1-0.1
Mean num. licks in bursts1.82.23.11.3-1.5-1.6-1.5-1.5-1.51.81.8-1.51.7-1.71.7-1.6-1.5-1.0-1.7-1.61.61.6-1.41.4-1.5-0.7-0.81.3-1.3
Cd content in liver1.31.44.22.0-1.0-1.7-1.3-1.2-1.20.90.8-1.21.3-1.31.3-1.4-1.1-1.1-1.2-1.11.01.1-0.50.5-0.4-0.8-0.01.5-1.5
Co content in liver0.60.72.21.5-0.7-0.1-0.9-1.0-1.00.70.5-0.80.9-0.90.9-1.1-0.9-0.4-1.0-0.90.91.0-0.70.7-0.60.1-0.90.3-0.3
Cu content in liver3.74.56.0-2.42.22.12.42.42.4-2.2-2.42.4-2.42.4-2.42.32.41.02.42.3-2.3-2.32.0-2.02.11.50.6-1.01.0
Fe content in liver0.20.23.20.3-0.8-0.7-0.2-0.2-0.20.4-0.0-0.00.2-0.20.2-0.0-0.1-1.80.10.0-0.0-0.1-0.10.10.4-0.00.80.0-0.0
K content in liver0.50.50.9-0.50.60.90.80.70.8-0.8-0.90.7-0.80.8-0.81.00.60.70.80.6-0.6-0.70.0-0.10.30.9-0.4-0.10.1
Mg content in liver0.80.92.3-1.10.91.21.11.01.0-1.0-1.10.9-1.11.1-1.11.10.90.81.00.8-0.8-0.90.1-0.20.51.5-0.80.0-0.0
Mn content in liver0.20.20.90.0-0.2-0.8-0.5-0.5-0.50.10.3-0.70.4-0.40.4-0.2-0.30.4-0.2-0.20.20.2-0.00.0-0.2-1.00.3-0.60.6
Na content in liver2.72.94.3-1.91.82.12.01.91.9-1.7-1.81.8-2.02.0-2.01.71.80.41.81.8-1.7-1.71.6-1.61.71.30.4-1.31.3
Rb content in liver0.10.10.60.1-0.0-0.1-0.0-0.1-0.1-0.1-0.10.0-0.00.0-0.00.2-0.00.60.0-0.10.10.0-0.40.4-0.30.0-0.30.8-0.8
Se content in liver0.81.01.5-0.90.90.61.01.01.0-1.0-1.11.0-1.01.0-1.01.21.00.21.21.1-1.1-1.21.0-1.11.1-0.11.0-0.80.8
Sr content in liver0.80.71.8-0.91.31.01.00.90.9-1.0-1.00.9-0.90.9-0.90.50.80.60.60.8-0.8-0.71.2-1.11.00.40.0-0.10.1
Zn content in liver1.21.31.9-0.91.00.91.21.31.3-1.3-1.21.3-1.31.3-1.31.31.30.51.41.3-1.3-1.41.2-1.21.10.21.0-0.80.8
Bone: minimum diameter0.50.92.31.3-1.5-1.5-1.1-1.1-1.11.11.0-1.11.0-1.01.0-0.8-0.9-0.8-0.7-0.70.70.6-0.70.6-0.7-1.10.9-0.40.4
Time in familiar zone, hab. session 10.10.11.20.00.1-0.4-0.1-0.1-0.1-0.20.3-0.30.1-0.10.10.2-0.01.0-0.0-0.00.00.00.0-0.0-0.3-1.10.30.3-0.3
Time in novel zone, hab. session 10.90.96.81.6-1.3-0.6-0.9-0.8-0.81.20.5-0.70.9-0.90.9-1.2-0.8-2.6-0.9-0.80.80.8-0.50.50.00.30.3-0.30.3
Total zone transitions, hab. session 13.54.98.3-2.02.51.72.42.42.4-2.9-2.32.5-2.32.3-2.32.92.62.52.52.5-2.4-2.52.1-2.21.7-0.61.7-0.80.8
Total locomotion distance, hab. session 12.12.97.1-1.11.40.61.61.61.6-2.0-1.71.7-1.61.6-1.62.31.90.92.12.0-2.0-2.11.8-1.91.6-1.12.7-1.31.3
Locomotion velocity, hab. session 12.33.25.7-1.51.60.91.81.81.8-2.2-1.91.8-1.71.7-1.72.42.01.32.22.1-2.1-2.21.8-1.91.7-0.62.3-1.21.2
Time in familiar zone, hab. session 20.20.21.2-0.30.1-0.80.00.00.00.10.0-0.0-0.10.1-0.1-0.10.1-0.40.20.3-0.4-0.30.9-0.90.7-0.71.1-0.00.0
Time in novel zone, hab. session 20.20.21.31.1-0.50.3-0.3-0.2-0.20.0-0.0-0.10.3-0.30.3-0.1-0.3-0.1-0.4-0.50.60.5-1.01.0-0.60.3-0.70.4-0.4
Total zone transitions, hab. session 20.70.93.1-0.91.00.80.90.80.9-1.6-1.31.0-0.80.8-0.81.41.01.81.00.9-0.9-1.00.5-0.50.5-0.30.20.1-0.1
Total locomotion distance, hab. session 20.60.81.7-1.00.81.10.90.90.9-1.3-1.30.9-0.90.9-0.91.00.90.71.00.9-0.9-0.90.7-0.70.90.50.4-0.80.8
Locomotion velocity, hab. session 21.21.62.9-1.41.21.41.31.31.3-1.7-1.71.3-1.21.2-1.21.51.31.01.41.3-1.3-1.31.0-1.01.20.60.6-0.90.9
Novel to familiar place preference ratio2.22.37.02.6-2.1-1.9-1.6-1.4-1.41.61.6-1.41.3-1.31.3-1.2-1.2-1.6-1.5-1.51.51.4-1.41.3-1.4-1.80.61.1-1.1
Novelty place preference3.03.18.62.9-2.3-2.3-1.9-1.7-1.71.91.9-1.71.6-1.61.6-1.5-1.5-1.7-1.7-1.71.71.7-1.51.5-1.6-2.10.71.3-1.3
Time in novel zone, NPP test3.83.910.53.2-2.6-2.5-2.1-1.9-1.92.12.2-1.91.8-1.81.8-1.7-1.7-1.8-2.0-2.02.01.9-1.81.7-1.9-2.30.61.5-1.5
Total zone transitions, NPP test2.73.87.8-1.52.21.52.12.12.1-2.8-2.22.2-2.02.0-2.02.62.32.42.22.1-2.1-2.21.7-1.81.5-0.71.5-0.60.6
Total locomotion distance, NPP test1.31.83.2-1.01.41.31.51.51.5-1.8-1.51.5-1.41.4-1.41.81.51.61.51.4-1.4-1.51.1-1.11.0-0.01.0-0.80.8
Locomotion velocity, NPP test2.23.14.6-1.71.91.61.91.91.9-2.1-1.91.9-1.81.8-1.82.11.91.62.01.9-1.9-1.91.7-1.71.50.21.2-1.21.2
Intraocular pressure0.20.32.10.5-0.3-0.6-0.5-0.5-0.50.30.7-0.70.5-0.50.5-0.4-0.50.6-0.5-0.50.50.5-0.40.4-0.8-1.40.2-0.00.1
Delta distance traveled before/after self-admin0.60.63.91.6-1.1-1.4-0.6-0.5-0.50.00.1-0.50.5-0.50.50.1-0.3-1.1-0.3-0.40.50.3-0.70.6-0.3-2.01.10.5-0.5
Delta ambulatory time before/after self-admin0.80.94.22.0-1.3-1.6-0.7-0.5-0.5-0.00.2-0.50.5-0.50.50.2-0.3-1.2-0.4-0.50.60.4-0.90.8-0.5-2.01.11.2-1.2
Parametrial fat weight0.20.31.00.0-0.20.1-0.6-0.7-0.70.50.5-0.70.5-0.50.5-0.8-0.70.1-0.7-0.60.60.7-0.50.5-0.50.2-1.0-0.00.0
Pavlov. Cond. lever latency0.81.13.51.9-1.2-1.0-1.0-0.9-0.91.11.3-1.20.9-0.90.9-1.0-0.8-1.3-1.1-1.11.11.1-0.80.8-0.9-1.40.3-0.10.1
Pavlov. Cond. magazine entry latency0.70.82.8-1.71.41.40.90.80.8-0.9-0.90.9-0.90.9-0.90.70.61.30.70.7-0.7-0.60.6-0.60.51.4-1.00.3-0.3
Pavlov. Cond. change in total contacts0.91.03.8-1.61.31.30.90.80.8-1.1-1.21.0-0.80.8-0.80.80.62.00.70.7-0.7-0.60.4-0.40.41.6-1.10.7-0.7
Pavlov. Cond. index score0.40.52.1-1.51.01.00.40.30.3-0.5-0.60.5-0.30.3-0.30.30.11.30.30.3-0.3-0.20.1-0.10.21.5-1.30.7-0.7
Pavlov. Cond. latency score0.30.42.1-1.30.80.90.40.30.3-0.5-0.60.5-0.30.3-0.30.30.11.00.30.3-0.3-0.20.1-0.10.31.5-1.20.7-0.7
Pavlov. Cond. lever contacts1.01.24.4-2.11.51.41.11.01.0-1.1-1.41.2-0.90.9-0.90.90.81.21.01.0-1.0-1.00.9-0.91.11.8-0.7-0.10.1
Pavlov. Cond. magazine entry number0.50.62.21.5-1.3-1.0-0.7-0.6-0.60.70.5-0.60.6-0.60.6-0.5-0.4-1.5-0.4-0.50.50.4-0.40.4-0.2-1.21.1-0.90.9
Pavlov. Cond. intertrial magazine entries0.91.01.8-0.70.91.31.21.21.2-1.1-1.21.4-1.31.3-1.31.31.21.31.01.0-0.9-1.00.5-0.50.50.70.10.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.50.63.0-1.71.21.10.60.50.5-0.7-0.70.7-0.50.5-0.50.50.31.50.50.5-0.5-0.40.4-0.30.31.3-1.20.5-0.5
Pavlov. Cond. response bias0.70.94.2-2.01.41.30.80.70.7-0.8-0.80.8-0.70.7-0.70.60.51.60.70.7-0.7-0.60.6-0.50.51.6-1.20.3-0.4
Pavlov. Cond. lever latency0.81.02.20.5-0.5-1.1-1.2-1.2-1.20.91.3-1.01.2-1.21.2-1.3-1.1-1.5-1.2-1.01.01.1-0.30.4-0.3-1.4-0.3-0.10.1
Pavlov. Cond. magazine entry latency3.43.910.4-1.92.02.92.42.42.4-1.8-1.92.3-2.32.3-2.32.32.13.22.01.8-1.7-1.80.8-0.80.32.2-0.7-0.30.3
Pavlov. Cond. change in total contacts0.70.96.8-0.30.11.60.80.90.9-0.4-0.70.7-0.80.8-0.81.00.72.60.60.3-0.2-0.4-0.80.8-1.01.8-1.10.6-0.6
Pavlov. Cond. index score2.12.78.8-1.41.42.31.91.91.9-1.5-1.61.8-1.91.9-1.92.01.73.01.71.5-1.4-1.50.5-0.50.12.0-0.4-0.10.1
Pavlov. Cond. latency score2.53.110.0-1.51.62.62.12.12.1-1.7-1.82.0-2.02.0-2.02.11.93.21.81.6-1.5-1.60.5-0.60.22.2-0.6-0.00.0
Pavlov. Cond. lever contacts0.71.03.0-0.60.51.31.11.11.1-0.7-1.20.9-1.11.1-1.11.21.01.71.20.9-0.9-1.10.1-0.20.11.6-0.0-0.20.1
Pavlov. Cond. magazine entry number1.92.310.21.4-1.4-2.4-1.8-1.8-1.81.31.2-1.71.8-1.81.8-1.9-1.6-3.2-1.5-1.31.21.3-0.20.30.3-1.70.70.2-0.2
Pavlov. Cond. intertrial magazine entries3.24.16.71.8-1.6-1.7-2.3-2.4-2.41.81.9-2.32.3-2.32.3-2.6-2.4-1.9-2.5-2.32.32.4-1.81.8-1.3-0.4-1.91.4-1.4
Pavlov. Cond. lever-magazine prob. diff.2.12.77.8-1.51.42.32.02.02.0-1.4-1.61.8-1.91.9-1.92.01.82.81.81.5-1.5-1.60.6-0.60.22.0-0.3-0.30.3
Pavlov. Cond. response bias0.91.25.4-0.80.71.61.21.21.2-0.8-1.21.1-1.31.3-1.31.41.12.31.20.9-0.9-1.00.0-0.1-0.21.7-0.4-0.10.1
Time in closed arm before self-admin4.55.09.1-2.22.12.52.62.62.6-2.0-2.32.7-2.42.4-2.42.02.4-0.02.42.4-2.4-2.42.3-2.32.43.01.0-0.90.9
Time in closed arm after self-admin0.60.61.40.2-0.6-0.9-0.9-1.0-1.00.80.6-0.91.0-1.01.0-1.2-0.9-1.0-0.8-0.80.70.8-0.40.4-0.10.5-0.80.7-0.7
Time in open arm before self-admin0.10.11.3-0.20.0-0.5-0.0-0.1-0.10.10.2-0.1-0.00.0-0.00.2-0.00.20.10.1-0.1-0.20.2-0.2-0.1-1.20.5-0.30.3
Time in open arm after self-admin0.80.92.1-0.70.50.10.80.90.9-0.5-0.70.8-0.90.9-0.90.80.9-0.70.91.0-1.0-1.01.1-1.11.1-0.71.5-1.41.4
Bone: periosteal estimation1.32.86.52.4-2.6-2.5-1.9-1.9-1.91.81.7-1.71.7-1.71.7-1.3-1.6-1.8-1.3-1.41.41.2-1.41.3-1.2-1.81.20.3-0.3
Bone: periosteal perimeter3.05.09.82.6-3.0-3.1-2.6-2.6-2.62.62.6-2.52.4-2.42.4-2.2-2.3-2.5-2.0-2.12.01.9-1.71.7-1.6-2.20.90.1-0.0
Bone: post-yield work0.40.50.90.9-0.6-0.3-0.7-0.7-0.70.50.3-0.70.8-0.80.8-0.7-0.8-0.2-0.8-0.80.80.8-1.01.0-0.60.1-0.90.9-0.9
Progressive ratio test 1 active lever presses0.60.61.60.4-0.3-0.2-0.6-0.6-0.60.50.8-0.80.7-0.70.7-0.7-0.70.4-0.9-0.90.91.0-1.01.0-1.0-0.1-1.30.9-0.9
Progressive ratio test 1 breakpoint0.30.30.90.1-0.1-0.1-0.4-0.5-0.50.30.7-0.60.6-0.60.6-0.5-0.60.4-0.7-0.70.70.7-0.70.7-0.8-0.3-1.00.6-0.6
Progressive ratio test 1 inactive lever presses1.01.14.70.5-0.50.3-0.8-0.8-0.80.70.2-0.90.9-0.90.9-1.3-1.1-0.1-1.2-1.21.21.3-1.21.2-0.61.6-2.20.9-0.9
Progressive ratio test 2 active lever presses0.30.32.8-0.10.50.40.0-0.1-0.0-0.4-0.10.0-0.00.0-0.00.2-0.11.7-0.2-0.20.30.3-0.60.6-0.70.0-1.20.9-0.9
Progressive ratio test 2 breakpoint0.40.42.20.20.20.3-0.2-0.3-0.3-0.10.2-0.20.2-0.20.2-0.1-0.41.4-0.4-0.50.50.6-0.80.9-0.80.3-1.51.1-1.1
Progressive ratio test 2 inactive lever presses0.40.42.4-0.30.71.30.40.30.3-0.8-1.10.3-0.30.3-0.30.20.21.0-0.0-0.10.10.2-0.40.50.21.3-1.60.6-0.6
Incentive Sensitization - Responses0.30.33.2-0.10.60.50.20.20.2-0.7-0.50.4-0.40.4-0.40.50.21.80.20.1-0.1-0.1-0.20.2-0.30.7-1.00.9-0.9
Incentive Sensitization - Breakpoint0.30.33.00.10.40.40.0-0.0-0.0-0.5-0.30.2-0.10.1-0.10.2-0.11.7-0.1-0.10.20.2-0.50.5-0.50.6-1.21.0-1.0
Sum of active levers in priming session hrs 5-60.10.10.8-0.20.10.20.20.20.20.0-0.30.2-0.20.2-0.2-0.00.1-0.90.10.1-0.1-0.10.2-0.20.50.8-0.0-0.00.0
Progressive ratio0.10.21.10.20.10.50.40.40.4-0.0-0.40.3-0.30.3-0.30.10.3-0.10.20.2-0.1-0.2-0.00.00.21.1-0.20.9-0.9
Food seeking constrained by brief footshock1.51.82.51.3-1.4-1.4-1.5-1.6-1.61.31.4-1.61.4-1.41.4-1.4-1.6-1.1-1.5-1.51.51.5-1.41.4-1.1-1.2-0.70.8-0.8
Seeking ratio, punishment vs. effort0.70.81.50.5-0.8-0.9-1.2-1.2-1.20.71.0-1.01.0-1.01.0-1.0-1.1-0.5-1.0-1.01.01.0-0.80.8-0.7-1.1-0.6-0.40.4
Retroperitoneal fat weight3.411.119.92.7-3.5-3.6-3.7-3.8-3.84.14.5-3.93.7-3.73.7-3.6-3.8-2.1-3.5-3.53.43.4-3.03.0-3.4-2.2-1.41.4-1.3
Reaction time number correct1.62.33.4-1.71.40.71.61.61.6-1.6-1.01.6-1.61.6-1.61.81.70.31.61.7-1.7-1.71.7-1.71.3-0.71.9-1.31.4
Reaction time mean minus median0.30.31.60.7-0.6-0.8-0.7-0.7-0.70.50.3-0.30.5-0.50.5-0.8-0.5-1.3-0.6-0.40.40.50.1-0.00.2-0.10.20.8-0.8
Reaction time mean minus median AUC0.81.12.30.8-0.9-1.3-1.2-1.2-1.21.31.0-0.80.9-0.90.9-1.4-1.1-1.2-1.1-1.00.91.0-0.30.4-0.5-0.2-0.31.5-1.5
Reaction time num false alarms0.20.31.70.2-0.3-0.3-0.2-0.1-0.1-0.2-0.60.0-0.10.1-0.1-0.00.1-0.80.30.3-0.4-0.40.7-0.71.0-0.41.3-1.11.1
Reaction time num false alarms AUC0.30.42.00.2-0.1-0.10.00.00.0-0.5-0.80.2-0.20.2-0.20.30.3-0.60.50.5-0.5-0.60.8-0.81.1-0.61.4-1.31.2
Reaction time trials correct on left1.62.33.4-1.71.40.71.61.61.6-1.6-1.01.6-1.61.6-1.61.81.70.31.61.7-1.7-1.71.7-1.71.3-0.71.9-1.31.4
Reaction time trials on left1.72.43.7-1.71.50.81.61.61.6-1.7-1.11.6-1.71.7-1.71.81.80.31.71.7-1.7-1.71.7-1.71.3-0.81.9-1.41.4
Reaction time mean0.10.10.5-0.20.20.40.20.20.2-0.2-0.40.5-0.60.6-0.6-0.00.3-0.70.20.3-0.3-0.20.4-0.40.50.70.00.0-0.0
Reaction time mean AUC0.10.10.4-0.30.30.30.20.20.2-0.2-0.30.5-0.50.5-0.50.00.2-0.50.20.3-0.3-0.20.4-0.40.50.6-0.00.2-0.2
Median of all reaction times0.30.40.9-0.60.50.80.60.60.6-0.5-0.60.8-0.90.9-0.90.40.6-0.20.50.5-0.5-0.50.5-0.50.60.9-0.0-0.20.2
Reaction time omissions0.30.40.9-0.50.60.40.60.60.6-1.0-0.90.7-0.70.7-0.70.50.70.50.50.6-0.6-0.60.9-0.90.8-0.20.7-0.30.3
Reaction time false alarm rate0.20.30.90.9-0.7-0.4-0.8-0.8-0.80.4-0.2-0.60.6-0.60.6-0.8-0.6-0.7-0.5-0.50.40.4-0.10.10.40.10.1-0.40.4
Reaction time premature initiation rate0.10.21.60.1-0.10.80.30.30.3-0.1-0.30.5-0.40.4-0.40.70.2-0.00.50.3-0.3-0.4-0.40.4-0.21.2-0.20.0-0.0
Reaction time premature initiations0.40.61.5-0.70.51.00.80.80.8-0.7-0.51.0-1.01.0-1.01.20.80.01.00.8-0.8-0.90.2-0.30.20.70.4-0.50.5
Std. dev. reaction times0.40.51.50.9-0.9-0.9-1.0-1.0-1.00.70.4-0.60.6-0.60.6-1.0-0.8-1.2-0.8-0.70.70.7-0.30.4-0.1-0.3-0.00.5-0.5
Reaction time trials completed1.72.43.7-1.71.50.81.61.61.6-1.7-1.11.6-1.71.7-1.71.81.80.31.71.7-1.7-1.71.7-1.71.3-0.81.9-1.41.4
Reaction time trials AUC1.31.93.3-1.51.20.61.41.51.5-1.5-0.91.4-1.51.5-1.51.71.60.21.51.5-1.5-1.61.5-1.51.1-0.71.8-1.21.2
Run reversals in cocaine runway, females1.21.12.8-1.30.80.20.80.80.8-1.1-1.20.9-0.70.7-0.71.11.0-0.51.21.2-1.2-1.21.3-1.31.6-0.81.7-1.11.1
Run reversals in cocaine runway, males0.50.55.41.0-0.6-1.1-0.7-0.7-0.70.20.6-0.50.4-0.40.40.1-0.40.4-0.4-0.40.50.4-0.60.5-0.8-2.30.90.4-0.4
Latency to leave start box in cocaine runway0.20.20.60.2-0.4-0.2-0.4-0.4-0.40.70.8-0.40.5-0.50.5-0.6-0.5-0.2-0.5-0.40.40.5-0.30.3-0.60.2-0.5-0.50.5
Latency to leave start box in cocaine runway, F0.30.41.2-0.60.50.70.50.50.5-0.3-0.40.7-0.50.5-0.50.50.50.80.60.6-0.6-0.60.6-0.60.20.40.3-1.11.1
Latency to leave start box in cocaine runway, M2.32.23.31.2-1.3-1.1-1.4-1.4-1.41.81.8-1.61.6-1.61.6-1.8-1.6-1.5-1.7-1.71.61.7-1.51.5-1.4-0.1-1.71.0-1.0
Std. dev. time between licks in bursts0.91.11.8-0.70.91.21.31.31.3-1.2-1.41.2-1.21.2-1.21.31.20.71.21.0-1.0-1.10.5-0.50.81.20.00.5-0.5
Total sessions with >9 infusions2.02.23.11.3-1.3-1.2-1.6-1.6-1.61.31.6-1.51.6-1.61.6-1.5-1.6-0.2-1.7-1.71.71.7-1.71.8-1.6-0.4-1.51.0-1.0
Short access day 1 total inactive lever presses1.31.53.11.7-1.5-0.7-1.3-1.2-1.20.80.5-1.41.2-1.21.2-1.1-1.2-0.7-1.4-1.51.51.5-1.71.7-1.0-0.4-0.90.5-0.5
Short access day 10 total inactive lever presses0.50.62.31.2-1.0-0.7-0.8-0.7-0.70.50.3-0.90.8-0.80.8-0.7-0.7-1.5-0.8-0.80.80.8-0.80.8-0.1-0.6-0.00.4-0.4
Short access day 1 total infusions2.22.33.51.5-1.5-1.0-1.7-1.7-1.71.11.0-1.61.7-1.71.7-1.8-1.7-0.6-1.8-1.81.91.9-1.81.9-1.1-0.1-1.70.7-0.7
Short access day 10 total infusions0.80.91.90.3-0.6-0.4-0.9-1.0-1.01.21.4-1.01.0-1.01.0-1.2-1.1-0.3-1.1-1.11.01.1-0.91.0-1.10.3-1.30.7-0.7
Short access total infusions2.83.26.11.3-1.4-0.9-1.9-2.0-2.01.61.6-1.92.0-2.02.0-2.2-2.1-0.4-2.1-2.12.12.2-2.12.1-1.60.2-2.50.8-0.8
Short access day 1 locomotion0.40.41.30.1-0.40.1-0.6-0.6-0.60.70.4-0.60.7-0.70.7-1.0-0.7-0.1-0.7-0.70.70.8-0.60.6-0.40.9-1.1-0.20.2
Short access day 10 total locomotion0.30.32.3-0.6-0.10.1-0.2-0.3-0.30.5-0.5-0.20.3-0.30.3-0.9-0.5-1.1-0.3-0.30.20.30.1-0.10.81.5-0.8-0.30.3
Short access total locomotion1.61.73.70.4-1.0-0.6-1.4-1.5-1.51.50.9-1.41.5-1.51.5-1.9-1.6-0.9-1.6-1.51.51.6-1.21.3-0.70.9-1.80.3-0.3
One hour access (0.3 mA shock)0.30.30.9-0.80.90.50.60.50.5-0.9-0.90.6-0.60.6-0.60.40.51.00.40.5-0.5-0.40.6-0.50.60.2-0.3-0.20.2
Compulsive drug intake2.42.48.1-0.71.71.41.61.61.6-2.3-1.61.6-1.71.7-1.72.11.72.91.61.6-1.5-1.51.2-1.20.6-0.30.8-0.80.8
One hour access (shock baseline)0.10.20.5-0.7-0.1-0.4-0.2-0.3-0.30.70.4-0.40.4-0.40.4-0.7-0.4-0.7-0.4-0.30.30.40.00.00.00.4-0.40.4-0.4
Social response proportion0.40.42.10.7-0.60.2-0.3-0.2-0.20.80.3-0.40.5-0.50.5-1.0-0.4-1.4-0.6-0.60.60.6-0.50.5-0.11.5-0.9-0.00.0
Social responses0.10.21.20.30.0-0.00.20.30.3-0.5-0.30.2-0.10.1-0.10.40.3-0.20.40.3-0.3-0.40.3-0.30.2-0.40.6-1.11.1
Social time1.41.93.5-1.91.81.51.41.41.4-1.5-1.61.6-1.51.5-1.51.31.31.21.41.4-1.4-1.41.4-1.31.31.6-0.1-0.60.6
Soleus weight0.10.31.8-0.00.60.70.30.30.3-1.2-1.00.5-0.40.4-0.40.70.41.30.40.3-0.2-0.3-0.00.00.2-0.1-0.50.6-0.7
Bone: stiffness1.72.63.71.7-1.8-1.1-1.8-1.8-1.81.91.7-1.81.8-1.81.8-1.8-1.9-1.0-1.8-1.81.81.8-1.81.8-1.6-0.0-1.40.6-0.6
Tibialis anterior weight0.51.64.9-0.91.62.21.51.51.5-1.4-1.61.5-1.41.4-1.40.91.40.01.01.0-1.0-0.91.0-1.01.31.6-0.6-0.60.6
Time to tail flick, vehicle, before self-admin0.10.10.70.7-0.3-0.2-0.1-0.0-0.0-0.10.3-0.0-0.00.0-0.00.40.1-0.30.20.1-0.1-0.2-0.10.0-0.2-0.70.80.3-0.3
Time to tail flick, vehicle, after self-admin1.51.65.1-0.50.70.01.21.31.3-1.1-0.91.3-1.21.2-1.21.41.4-0.61.51.5-1.5-1.61.6-1.61.4-0.82.3-0.60.6
Time to tail flick, test, before self-admin0.20.21.60.1-0.1-1.0-0.3-0.3-0.3-0.10.0-0.10.2-0.20.20.1-0.1-0.30.10.1-0.2-0.20.4-0.40.3-1.30.70.3-0.4
Time to tail flick, test, after self-admin1.21.21.8-1.31.20.71.21.21.2-1.3-1.30.9-1.21.2-1.21.11.20.71.21.2-1.3-1.21.3-1.31.30.50.8-0.40.4
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.20.30.30.40.50.5-0.1-0.40.5-0.40.4-0.40.10.3-0.40.30.3-0.3-0.30.3-0.30.50.70.0-0.20.2
Delta time to tail flick, test, before/after SA2.32.13.2-1.41.41.51.71.71.7-1.7-1.81.4-1.61.6-1.61.51.70.81.51.5-1.5-1.51.3-1.31.41.30.8-0.80.8
Tibia length0.82.23.61.8-1.6-1.9-1.5-1.5-1.51.31.7-1.51.4-1.41.4-0.8-1.30.1-1.3-1.41.51.3-1.81.7-1.9-1.7-0.31.7-1.7
Ambulatory time before self-admin0.30.31.9-0.50.40.7-0.1-0.2-0.2-0.2-0.5-0.20.2-0.20.2-0.4-0.31.2-0.3-0.30.30.4-0.30.30.01.0-1.4-0.40.4
Ambulatory time after self-admin0.30.31.40.20.30.10.50.50.5-1.1-1.20.6-0.50.5-0.50.80.60.10.50.4-0.3-0.4-0.0-0.00.6-0.10.30.9-0.9
Bone: tissue strength0.10.10.70.9-0.6-0.4-0.2-0.2-0.20.30.4-0.10.2-0.20.20.0-0.2-0.3-0.2-0.30.30.2-0.60.6-0.5-0.40.10.4-0.4
Total heroin consumption0.10.21.00.3-0.10.2-0.3-0.2-0.2-0.10.1-0.10.3-0.30.3-0.1-0.21.0-0.2-0.30.30.3-0.50.5-0.60.3-0.60.6-0.7
Bone: trabecular number0.10.20.9-0.50.10.10.10.10.10.20.20.2-0.10.1-0.10.10.1-0.90.20.2-0.2-0.20.4-0.40.4-0.50.6-1.01.0
Bone: trabecular spacing1.21.52.41.1-1.0-1.2-1.2-1.2-1.21.11.3-1.31.2-1.21.2-1.2-1.30.6-1.3-1.31.31.3-1.41.4-1.5-0.4-1.11.5-1.5
Bone: trabecular thickness0.40.52.8-0.60.20.90.40.40.4-0.1-0.50.6-0.40.4-0.40.20.3-1.10.50.4-0.5-0.50.5-0.50.80.70.1-1.71.7
Bone: trabecular tissue density1.01.54.4-0.61.02.01.31.41.4-1.0-1.61.5-1.41.4-1.41.11.2-0.11.21.1-1.1-1.10.8-0.81.22.1-0.1-0.50.5
Water consumed over 24 hours1.01.23.41.7-1.0-1.2-1.0-1.0-1.00.71.0-0.91.0-1.01.0-0.7-0.9-0.5-1.0-1.01.11.0-1.21.1-1.1-1.0-0.21.9-1.9
Number of responses in last shaping day0.60.65.7-0.90.91.50.70.60.6-0.8-1.00.6-0.50.5-0.50.10.40.70.30.3-0.3-0.20.2-0.20.62.4-1.1-0.10.1