Hub : Genes

Mdc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Mdc1 0.34 0.19 2.5e-12 0.11 0.13 0.12 0.12 9.8e-11 4.2e-12 1.2e-11 3.2e-11
2 Adipose gene expression Mdc1 0.63 0.1 0.0e+00 0.69 0.68 0.69 0.69 3.1e-105 2.9e-104 3.4e-107 3.4e-107
3 LHb gene expression Mdc1 0.17 0.11 2.1e-03 0.02 -0.01 -0 0.15 9.6e-02 5.0e-01 3.4e-01 2.0e-04
4 PL gene expression Mdc1 0.29 0.1 0.0e+00 0.34 0.34 0.34 0.34 1.3e-37 1.0e-38 1.0e-37 3.3e-38
5 pVTA gene expression Mdc1 0.35 0.09 0.0e+00 0.47 0.3 0.48 0.26 3.4e-42 2.9e-24 4.7e-43 2.2e-21
6 Liver gene expression Mdc1 0.6 0.14 0.0e+00 0.51 0.54 0.54 0.54 4.7e-66 5.5e-72 4.9e-71 5.2e-72
7 IC gene expression Mdc1 0.46 0.13 0.0e+00 0.31 0.32 0.31 0.17 1.9e-13 3.7e-14 1.1e-13 1.2e-07
8 PL mRNA stability Mdc1 0.1 0.05 1.3e-11 0.1 0.1 0.08 0.1 1.9e-11 3.9e-11 1.9e-09 4.5e-11
9 Brain gene expression Mdc1 0.73 0.01 0.0e+00 0.31 0.39 0.38 0.38 1.5e-29 8.3e-39 3.3e-37 7.3e-37
10 Adipose mRNA stability Mdc1 0.4 0.12 0.0e+00 0.48 0.47 0.48 0.48 2.5e-60 2.6e-58 2.3e-59 1.3e-59
11 OFC gene expression Mdc1 0.15 0.11 8.8e-03 0.07 0.04 0 0.06 1.0e-02 3.4e-02 3.0e-01 1.8e-02
12 IC mRNA stability Mdc1 0.13 0.08 4.1e-04 0.07 0.06 0.04 0.04 8.9e-04 2.1e-03 7.6e-03 5.9e-03
13 Liver mRNA stability Mdc1 0.11 0.07 1.2e-12 0.07 0.1 0.09 0.1 1.8e-08 7.4e-11 1.5e-10 9.9e-11
14 NAcc gene expression Mdc1 0.3 0.11 0.0e+00 0.29 0.29 0.3 0.3 4.1e-44 4.1e-44 8.9e-46 4.0e-46
15 BLA gene expression Mdc1 0.45 0.15 0.0e+00 0.26 0.32 0.34 0.33 7.6e-14 1.8e-17 1.4e-18 2.6e-18
16 NAcc mRNA stability Mdc1 0.05 0.03 7.3e-07 0.04 0.04 0.04 0.04 6.2e-07 3.1e-06 1.8e-06 1.4e-06
17 pVTA mRNA stability Mdc1 0.15 0.08 1.8e-13 0.18 0.09 0.14 0.01 1.2e-14 1.6e-07 3.1e-11 7.7e-02
18 PL alternative TSS XM_039098645.2 0.02 0.02 7.7e-03 0.01 0.01 0 0.01 2.7e-02 7.1e-02 1.4e-01 2.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.61.02.50.70.81.60.91.21.20.90.91.20.80.80.91.11.20.80.80.90.0
Area under the delay curve1.61.82.8-1.4-1.3-1.4-1.4-1.6-1.5-1.4-1.7-1.5-1.0-1.0-1.7-1.5-1.5-1.3-1.1-1.00.0
BMI with tail1.96.59.3-3.1-2.8-1.8-2.7-2.5-2.6-2.6-2.6-2.5-3.0-3.0-2.5-2.5-2.5-2.6-2.6-2.40.0
BMI without tail3.811.513.7-3.5-3.6-3.2-3.6-3.6-3.5-3.6-3.7-3.5-3.4-3.4-3.5-3.5-3.4-3.5-3.5-3.20.0
Body weight5.423.830.6-4.0-5.0-5.5-5.2-5.4-5.3-5.2-4.9-5.5-4.8-4.8-4.8-5.3-5.3-4.9-4.6-4.60.0
Weight adjusted by age1.82.75.5-1.4-1.6-2.3-1.6-1.8-1.9-1.6-1.0-1.9-1.1-1.1-1.6-1.7-1.8-1.8-1.6-1.3-1.6
Bone surface0.00.00.40.1-0.0-0.6-0.1-0.2-0.0-0.2-0.1-0.20.10.1-0.0-0.2-0.0-0.0-0.1-0.10.0
Bone volume0.10.10.2-0.3-0.4-0.4-0.4-0.3-0.2-0.5-0.4-0.3-0.3-0.3-0.4-0.4-0.2-0.5-0.4-0.40.0
Breakpoint value in progressive ratio session0.40.51.10.80.70.60.70.70.50.70.90.80.60.60.70.70.60.60.91.00.3
Number of licking bursts0.50.91.40.91.00.31.10.80.81.10.90.81.11.11.00.80.81.21.11.00.0
Context. condit. distance diff. score8.910.814.13.83.62.43.53.23.33.43.43.33.43.43.43.33.43.43.53.50.0
Locomotion velocity, session 10.50.60.80.90.80.50.80.70.80.80.90.70.80.80.80.70.70.80.80.80.0
Locomotion distance, session 10.00.10.7-0.30.00.80.10.30.20.20.20.3-0.0-0.00.00.30.30.0-0.00.10.0
Locomotion velocity, session 20.10.10.20.30.30.00.30.20.20.20.50.10.30.30.30.20.10.20.30.30.0
Locomotion distance, session 20.20.20.50.30.40.70.40.50.40.50.50.50.50.50.40.50.50.40.40.50.0
Locomotion velocity, session 30.20.20.4-0.6-0.5-0.0-0.5-0.4-0.4-0.5-0.6-0.4-0.5-0.5-0.5-0.4-0.4-0.5-0.5-0.60.0
Locomotion distance, session 31.01.01.61.01.01.31.11.11.11.00.81.21.01.00.91.11.21.01.01.00.0
Stereotopy head waving bouts, day 30.70.83.0-0.5-0.7-1.7-0.8-1.1-1.1-0.8-0.6-1.1-0.7-0.7-0.7-1.0-1.0-0.8-0.6-0.70.0
Stereotopy head waving duration, day 30.60.72.2-0.6-0.8-1.5-0.8-1.0-1.0-0.8-0.6-1.0-0.8-0.8-0.7-0.9-1.0-0.8-0.6-0.70.0
Locomotion velocity, session 74.44.85.82.12.32.32.32.42.42.22.22.42.02.02.32.42.42.22.22.20.0
Locomotion distance, session 73.03.75.81.71.92.42.02.22.22.01.82.21.81.81.92.12.21.91.71.90.0
Stereotopy head waving bouts, day 72.62.94.7-1.5-1.7-2.2-1.7-1.9-1.9-1.7-1.4-1.9-1.7-1.7-1.6-1.8-1.8-1.7-1.7-1.70.0
Stereotopy head waving duration, day 72.53.04.7-1.5-1.7-2.2-1.8-1.9-1.9-1.8-1.5-1.9-1.7-1.7-1.6-1.8-1.9-1.8-1.7-1.60.0
Locomotion velocity, session 81.21.43.31.81.5-0.21.30.80.81.21.30.81.41.41.40.90.91.31.51.50.0
Locomotion distance, session 84.76.88.93.02.82.02.72.62.62.62.82.62.82.82.72.62.72.72.82.80.0
Degree of sensitization distance0.70.81.20.91.00.51.00.90.91.01.10.80.90.91.00.80.91.00.80.90.0
Degree of sensitization stereotypy1.31.41.9-1.1-1.2-1.4-1.2-1.3-1.2-1.2-0.9-1.3-1.2-1.2-1.1-1.2-1.3-1.2-1.3-1.20.0
Conditioned locomotion0.40.41.0-0.4-0.6-1.0-0.6-0.7-0.9-0.6-0.5-0.8-0.5-0.5-0.5-0.7-0.9-0.7-0.5-0.50.0
Cocaine response after cond. corrected0.40.50.90.50.71.00.70.70.70.80.80.80.70.70.60.80.70.70.80.70.0
Cocaine response after cond. not corrected0.00.00.10.30.2-0.30.2-0.0-0.00.10.3-0.00.20.20.20.0-0.10.20.30.30.0
Cocaine response before conditioning2.63.18.1-1.1-1.6-2.8-1.7-2.1-2.0-1.8-1.5-2.1-1.5-1.5-1.5-2.0-2.0-1.6-1.5-1.60.0
Saline control response2.73.64.8-2.1-2.1-1.3-2.1-1.8-1.7-2.1-2.2-1.8-2.0-2.0-1.9-1.9-1.8-2.0-2.0-2.10.0
Bone: connectivity density2.13.24.11.71.82.01.82.02.01.81.72.01.71.71.81.92.01.71.71.80.0
Bone: cortical apparent density0.71.01.7-1.3-1.2-0.2-1.2-0.8-0.9-1.1-1.1-0.9-1.0-1.0-1.1-0.9-1.0-1.2-1.2-1.10.0
Bone: cortical area1.52.33.1-1.3-1.5-1.8-1.6-1.6-1.6-1.6-1.5-1.7-1.4-1.4-1.5-1.6-1.6-1.5-1.4-1.50.0
Bone: cortical porosity0.70.71.0-1.0-0.8-0.8-0.9-1.0-0.9-0.9-1.0-0.9-0.7-0.7-0.9-0.9-0.8-0.8-0.9-0.80.0
Bone: cortical porosity0.30.30.8-0.6-0.5-0.9-0.5-0.7-0.7-0.5-0.6-0.7-0.4-0.4-0.5-0.7-0.6-0.5-0.5-0.50.0
Bone: cortical thickness4.67.79.8-3.1-3.1-1.9-3.0-2.7-2.7-2.9-3.0-2.7-2.8-2.8-2.9-2.7-2.8-3.0-2.9-3.00.0
Bone: cortical thickness2.12.43.9-2.0-1.9-0.4-1.7-1.3-1.4-1.6-1.5-1.4-1.9-1.9-1.7-1.4-1.4-1.7-1.7-1.70.0
Bone: cortical tissue density0.60.81.3-1.1-1.0-0.1-1.0-0.7-0.8-0.9-0.9-0.7-0.9-0.9-1.0-0.7-0.9-1.1-1.0-1.00.0
Condit. Reinf. active minus inactive responses0.80.81.10.90.91.10.91.01.00.91.01.01.01.00.91.00.90.80.80.90.0
Condit. Reinf. active-inactive response ratio0.10.10.2-0.5-0.40.1-0.3-0.2-0.3-0.3-0.3-0.2-0.4-0.4-0.3-0.2-0.3-0.3-0.4-0.40.0
Condit. Reinf. active responses1.21.52.01.21.21.41.21.31.31.21.31.31.41.41.11.31.31.11.21.10.0
Condit. Reinf. inactive responses1.51.83.31.21.31.81.21.51.51.21.31.51.41.41.21.41.51.21.41.20.0
Incentive salience index mean2.32.83.81.91.81.31.81.61.61.71.81.61.91.91.71.71.61.71.71.70.0
Condit. Reinf. lever presses4.36.18.52.92.71.82.62.42.52.52.72.42.62.62.62.52.52.62.52.60.0
Condit. Reinf. active minus inactive responses0.60.71.2-0.8-0.8-1.0-0.9-1.0-1.0-0.8-0.8-1.1-0.6-0.6-0.9-1.0-1.1-0.8-0.6-0.90.0
Condit. Reinf. active-inactive response ratio1.11.32.9-1.0-1.0-1.7-1.1-1.4-1.4-1.1-0.9-1.4-0.8-0.8-1.0-1.4-1.5-1.1-0.8-1.10.0
Condit. Reinf. active responses0.10.10.30.20.30.40.20.20.30.30.30.20.50.50.20.20.20.20.40.20.0
Condit. Reinf. inactive responses1.21.62.91.21.21.71.21.41.51.21.01.41.21.21.21.41.51.21.11.20.0
Condit. Reinf. lever presses0.81.01.40.91.11.11.11.11.11.11.21.01.01.01.01.11.11.11.01.00.0
Condit. Reinf. lever reinforcers received0.20.20.60.50.50.40.50.40.50.50.40.40.80.80.50.40.40.50.60.40.0
Conditioned reinforcement - actives1.11.82.6-1.2-1.2-1.5-1.3-1.5-1.6-1.5-1.5-1.2-1.2-1.2-1.3-1.4-1.3-1.6-1.5-1.3-0.4
Conditioned reinforcement - inactives1.32.03.0-1.5-1.2-1.5-1.4-1.6-1.7-1.5-1.3-1.4-1.0-1.0-1.6-1.5-1.6-1.7-1.4-1.3-0.6
Conditioned locomotion0.10.10.4-0.2-0.1-0.6-0.2-0.3-0.4-0.4-0.2-0.40.30.3-0.1-0.5-0.4-0.3-0.4-0.40.6
Patch foraging indifference point 0 sec0.71.31.9-1.4-1.2-0.6-1.2-1.1-1.2-1.2-1.1-0.8-1.4-1.4-1.3-1.0-1.0-1.2-1.1-1.00.0
Patch foraging indifference point AUC0.81.21.8-1.1-1.2-1.3-1.2-1.3-1.0-1.2-1.0-1.3-0.8-0.8-1.1-1.3-1.2-0.9-1.2-1.30.0
Delay disc. indifference point, 0s delay0.20.20.5-0.3-0.4-0.7-0.4-0.7-0.7-0.4-0.5-0.5-0.1-0.1-0.5-0.5-0.5-0.5-0.3-0.30.0
Delay disc. indifference point, 16s delay2.62.95.3-2.3-1.8-1.1-1.9-1.7-1.7-1.8-2.2-1.7-1.4-1.4-2.0-1.8-1.7-1.7-1.5-1.60.0
Delay disc. indifference point, 2s delay1.21.32.7-0.9-1.1-1.6-1.1-1.5-1.5-1.0-1.2-1.2-1.0-1.0-1.3-1.3-1.2-1.1-0.9-0.90.0
Delay disc. indifference point, 24s delay0.50.61.0-1.0-0.8-0.3-0.8-0.8-0.7-0.7-0.9-0.8-0.8-0.8-0.9-0.8-0.6-0.7-0.9-0.60.0
Delay disc. indifference point, 4s delay1.92.03.8-1.1-1.3-1.9-1.5-1.8-1.8-1.5-1.5-1.7-0.9-0.9-1.5-1.6-1.8-1.5-1.0-1.10.0
Delay disc. indifference point, 8s delay0.30.41.1-0.7-0.6-0.6-0.6-0.8-0.6-0.6-1.0-0.7-0.4-0.4-0.9-0.6-0.6-0.6-0.5-0.30.0
Indifference point function ln k0.30.60.80.80.90.90.90.70.60.90.80.70.60.60.80.80.70.90.70.80.0
Indifference point function log k0.30.60.80.80.90.90.90.70.60.90.80.70.60.60.80.80.70.90.70.80.0
Patch foraging total patch changes 0 sec1.01.82.8-1.7-1.5-0.7-1.5-1.3-1.4-1.4-1.4-1.1-1.6-1.6-1.6-1.3-1.3-1.4-1.4-1.30.0
Patch foraging total patch changes 12 sec1.51.93.3-1.8-1.6-0.8-1.5-1.4-1.3-1.4-1.5-1.2-1.6-1.6-1.6-1.3-1.2-1.4-1.4-1.30.0
Patch foraging total patch changes 18 sec0.71.02.3-1.5-1.20.3-1.1-0.8-0.7-1.0-1.2-0.6-1.1-1.1-1.3-0.9-0.7-0.9-1.1-1.10.0
Patch foraging total patch changes 24 sec0.10.20.9-0.9-0.50.7-0.5-0.0-0.1-0.4-0.40.1-0.7-0.7-0.6-0.1-0.1-0.5-0.5-0.40.0
Patch foraging total patch changes 6 sec1.32.13.8-1.9-1.6-0.7-1.6-1.3-1.3-1.4-1.5-1.1-1.8-1.8-1.6-1.3-1.3-1.4-1.5-1.40.0
Patch foraging time to switch 0 sec0.00.00.3-0.2-0.10.5-0.00.30.20.0-0.20.3-0.2-0.2-0.10.20.1-0.20.00.00.0
Patch foraging water rate 0 sec0.51.01.7-1.3-1.1-0.7-1.1-1.0-1.1-0.9-0.6-1.2-1.2-1.2-0.9-1.0-1.1-0.8-1.2-1.00.0
Patch foraging water rate 12 sec0.00.10.4-0.6-0.20.1-0.4-0.1-0.1-0.30.2-0.3-0.1-0.1-0.1-0.2-0.2-0.4-0.4-0.30.0
Patch foraging water rate 18 sec0.10.20.5-0.3-0.3-0.7-0.5-0.5-0.5-0.60.2-0.7-0.2-0.2-0.2-0.5-0.6-0.5-0.4-0.30.0
Patch foraging water rate 24 sec1.72.43.5-1.7-1.7-1.3-1.7-1.5-1.4-1.7-1.0-1.8-1.6-1.6-1.4-1.6-1.6-1.4-1.9-1.70.0
Patch foraging water rate 6 sec0.20.20.9-1.0-0.50.2-0.5-0.4-0.3-0.4-0.0-0.5-0.6-0.6-0.4-0.4-0.3-0.3-0.7-0.60.0
Seeking ratio, delayed vs. immediate footshock0.40.41.6-0.5-0.8-1.0-0.7-0.5-0.7-0.7-0.2-0.7-0.4-0.4-0.3-0.6-0.8-0.7-0.5-0.2-1.3
Distance traveled before self-admin0.10.20.70.80.3-0.60.3-0.1-0.10.1-0.40.10.60.60.20.0-0.00.10.20.20.8
Distance traveled after self-admin0.60.72.9-0.2-0.7-1.7-0.7-0.9-1.0-0.8-0.7-0.8-1.1-1.1-0.4-0.9-0.9-0.6-0.6-0.4-0.6
Extensor digitorum longus weight0.00.20.50.70.5-0.30.40.20.30.30.30.20.50.50.40.20.40.50.50.40.0
Bone: elastic displacement0.60.71.1-1.0-0.9-0.4-0.9-0.8-0.9-0.8-1.0-0.7-1.0-1.0-0.8-0.7-0.8-0.9-0.9-0.80.0
Bone: elastic work2.63.44.0-1.9-2.0-1.8-1.9-1.9-2.0-1.8-1.9-1.9-2.0-2.0-1.8-1.9-1.9-1.9-1.9-1.80.0
Bone: endosteal estimation0.20.55.30.70.1-2.3-0.1-0.9-0.7-0.4-0.0-0.9-0.1-0.1-0.0-0.8-0.6-0.10.00.00.0
Bone: endosteal perimeter0.91.94.52.11.7-0.41.60.91.01.41.70.91.51.51.61.01.11.61.71.60.0
Epididymis fat weight4.214.228.4-5.3-4.5-0.7-4.2-3.1-3.3-3.9-4.1-3.1-4.5-4.5-4.3-3.3-3.4-4.0-3.9-3.90.0
Delta time in closed arm before/after self-admin0.50.50.9-0.9-0.7-0.7-0.7-0.7-0.7-0.6-0.6-0.7-0.8-0.8-0.8-0.7-0.7-0.5-0.7-0.6-0.6
Delta time in open arm before/after self-admin0.20.20.70.2-0.3-0.4-0.4-0.5-0.6-0.6-0.8-0.4-0.2-0.2-0.3-0.5-0.5-0.7-0.5-0.4-0.1
Diff in mean of infusions in LGA sessions3.74.66.61.82.22.42.22.12.12.11.42.52.62.61.72.12.21.82.11.92.3
Delay discount exponential model param1.71.82.91.41.31.41.41.71.51.41.71.51.01.01.71.51.51.31.11.00.0
Extinction: sum of active levers before priming0.70.81.80.50.80.60.90.90.81.00.50.91.41.40.60.90.90.90.91.00.7
Active lever presses in extinction session 60.10.10.3-0.3-0.10.3-0.10.1-0.0-0.1-0.30.1-0.5-0.5-0.10.00.1-0.20.00.0-0.4
Bone: final force6.410.211.6-3.2-3.4-3.0-3.4-3.3-3.2-3.3-3.3-3.3-3.4-3.4-3.3-3.3-3.2-3.2-3.2-3.30.0
Bone: final moment5.58.910.0-2.9-3.2-2.8-3.2-3.1-3.0-3.1-3.1-3.1-3.1-3.1-3.1-3.1-3.0-3.0-3.0-3.00.0
Food consumed during 24 hour testing period0.20.21.10.1-0.4-1.0-0.4-0.6-0.5-0.5-0.4-0.7-0.4-0.4-0.2-0.5-0.5-0.5-0.3-0.30.0
Glucose3.14.88.62.92.50.72.31.91.92.22.41.82.72.72.41.91.92.42.42.40.0
Heart weight1.92.93.9-1.8-1.8-1.7-1.7-1.8-1.8-1.6-1.7-1.7-1.8-1.8-1.6-1.8-1.7-1.3-2.0-2.00.0
Delay discount hyperbolic model param1.81.93.01.51.41.51.51.71.61.41.71.51.11.11.71.51.61.41.11.00.0
Intermittent access intake day 1-15 change0.00.10.10.30.20.10.20.40.40.20.30.20.10.10.30.30.20.10.20.1-0.2
Intermittent access intake escalation0.10.10.7-0.1-0.3-0.3-0.4-0.1-0.1-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.2-0.5-0.2-0.2-0.8
Intermittent access intake escalation 20.10.10.50.70.4-0.10.20.30.40.20.50.10.20.20.40.30.20.20.50.3-0.2
Intermitt. access day 1 inactive lever presses0.00.10.6-0.10.1-0.80.0-0.2-0.30.10.5-0.40.20.20.2-0.3-0.30.0-0.20.10.7
Intermitt. access day 15 inactive lever presses0.61.21.8-1.2-1.1-1.2-1.2-1.2-1.1-1.1-0.6-1.3-1.0-1.0-1.1-1.2-1.1-1.0-1.3-1.0-0.9
Intermitt. access escalation Index3.14.35.92.22.22.02.22.12.02.11.92.21.81.82.12.12.11.92.12.22.4
Intermittent access day 1 total infusions0.00.10.60.20.10.40.1-0.1-0.3-0.1-0.40.50.10.1-0.20.00.2-0.20.00.10.8
Intermittent access day 15 total infusions0.10.10.5-0.1-0.3-0.2-0.4-0.4-0.5-0.5-0.6-0.1-0.1-0.1-0.5-0.4-0.3-0.7-0.3-0.3-0.2
Intermittent access terminal intake (last 3 days)0.40.61.1-0.6-0.7-0.6-0.8-0.8-0.9-0.9-0.9-0.5-0.5-0.5-0.9-0.8-0.7-1.1-0.7-0.8-0.5
Intermittent access total infusions0.20.30.6-0.2-0.4-0.4-0.5-0.7-0.7-0.7-0.8-0.2-0.3-0.3-0.7-0.6-0.4-0.8-0.5-0.50.1
Intermittent access day 1 locomotion0.10.20.50.70.40.20.30.20.10.10.00.50.70.70.30.30.20.10.40.40.6
Intermittent access day 15 total locomotion0.51.02.5-0.3-0.7-1.6-1.0-1.3-1.2-1.2-0.4-1.1-0.6-0.6-1.0-1.2-1.2-1.1-0.9-0.90.0
Intermittent access total locomotion0.70.81.5-0.3-0.7-1.2-0.9-1.1-1.2-1.2-0.8-1.0-0.5-0.5-0.9-1.1-1.1-1.1-0.8-0.8-0.2
Intermittent access standard deviation1.93.94.5-2.0-2.0-2.1-2.1-1.8-1.9-2.1-2.1-2.0-1.7-1.7-1.8-2.0-2.0-2.1-2.1-2.1-2.0
Left kidney weight4.420.525.0-4.1-4.7-4.8-4.8-4.8-4.8-4.8-4.4-5.0-4.7-4.7-4.2-4.8-4.9-4.5-4.5-4.70.0
Right kidney weight4.520.525.8-3.7-4.7-5.1-4.8-5.0-4.9-4.9-4.6-5.0-4.4-4.4-4.4-4.8-4.9-4.6-4.4-4.50.0
Cocaine induced anxiety1.01.41.91.31.21.11.21.01.11.21.41.01.31.31.11.11.11.21.21.21.4
Post-drug Anxiety0.70.71.80.50.71.30.80.80.91.00.70.71.01.00.70.90.81.10.81.00.2
Baseline Anxiety0.20.20.9-0.9-0.10.90.00.40.20.3-0.40.30.00.00.10.30.20.30.00.1-1.0
Tail length1.97.620.1-1.2-2.4-4.5-2.7-3.5-3.2-2.9-2.6-3.4-2.0-2.0-2.6-3.2-3.1-2.6-2.3-2.30.0
Length with tail2.812.030.8-1.6-3.2-5.5-3.5-4.2-4.0-3.7-3.1-4.3-2.7-2.7-3.2-4.0-4.0-3.2-2.9-3.10.0
Length without tail3.210.219.9-2.1-3.1-4.5-3.3-3.6-3.6-3.3-2.9-3.8-3.0-3.0-2.9-3.5-3.6-3.0-2.8-3.10.0
Times rat made contact with spout0.20.21.6-0.00.21.30.30.70.60.40.00.7-0.2-0.20.30.60.70.30.20.20.0
Lifetime Intake0.50.61.4-0.4-0.6-0.7-0.7-1.0-1.1-0.9-1.2-0.5-0.5-0.5-1.0-0.8-0.7-1.1-0.7-0.70.1
Liver weight, left0.20.31.81.30.6-1.30.4-0.1-0.10.20.5-0.00.40.40.60.1-0.10.30.60.70.0
Liver weight, right0.50.96.00.4-0.6-2.4-0.7-1.2-1.2-0.9-0.7-1.1-0.5-0.5-0.5-1.1-1.1-0.7-0.4-0.20.0
Locomotor activity0.10.21.30.70.2-1.10.1-0.3-0.1-0.00.6-0.5-0.0-0.00.4-0.2-0.30.30.20.10.0
Locomotor testing distance0.10.20.60.50.4-0.20.40.20.30.40.70.00.30.30.50.20.10.70.40.20.0
Locomotor testing rearing0.00.10.20.2-0.1-0.4-0.1-0.4-0.3-0.20.0-0.4-0.1-0.1-0.0-0.3-0.30.10.1-0.20.0
Locomotion in novel chamber0.60.81.3-0.6-0.7-1.1-0.9-1.0-1.0-1.0-1.1-0.9-0.8-0.8-0.9-1.0-1.0-0.9-0.7-0.8-0.4
Locomotion in novel chamber post-restriction1.11.82.7-1.5-1.3-1.0-1.4-1.3-1.5-1.3-1.1-1.3-1.6-1.6-1.1-1.2-1.5-1.4-1.0-1.0-1.6
Fecal boli incidents, locomotor time 10.50.71.21.00.60.80.80.80.90.80.81.10.60.60.70.81.11.10.90.90.0
Change in fecal boli incidents, locomotor task0.60.60.9-0.9-0.6-0.7-0.7-0.7-0.9-0.6-0.3-0.9-0.9-0.9-0.7-0.8-1.0-0.7-0.7-0.70.0
Time >=10cm from walls, locomotor time 10.20.21.10.1-0.2-1.1-0.2-0.5-0.5-0.2-0.4-0.4-0.5-0.5-0.2-0.4-0.4-0.3-0.20.10.0
Bouts of movement, locomotor time 11.01.11.61.31.01.21.11.01.21.10.61.01.11.11.11.21.21.11.21.20.0
Total resting periods, locomotor time 10.60.71.21.10.80.70.90.70.80.80.30.80.90.90.80.80.80.91.10.90.0
Rest time, locomotor task time 10.00.10.40.60.1-0.40.10.0-0.00.10.10.0-0.0-0.00.20.0-0.10.20.30.50.0
Distance moved, locomotor task time 10.60.91.6-1.2-0.8-1.0-1.0-0.9-1.0-0.9-0.8-0.9-0.9-0.9-0.8-1.0-0.8-1.0-1.2-1.30.0
Vertical activity count, locomotor time 10.20.61.2-1.1-0.7-0.5-0.8-0.6-0.7-0.7-0.6-0.8-0.9-0.9-0.6-0.7-0.7-0.8-1.0-1.00.0
Time >=10cm from walls, locomotor time 20.00.00.10.30.1-0.10.30.10.00.3-0.10.1-0.1-0.10.30.10.10.20.00.20.0
Bouts of movement, locomotor time 20.10.10.40.4-0.2-0.5-0.1-0.2-0.3-0.20.6-0.5-0.3-0.30.2-0.1-0.4-0.2-0.20.20.0
Total resting periods, locomotor time 20.10.10.90.70.2-0.30.30.00.10.21.0-0.20.00.00.60.2-0.10.20.20.60.0
Rest time, locomotor task time 21.21.53.71.91.30.31.41.11.11.21.60.91.11.11.61.11.01.31.41.50.0
Distance moved, locomotor task time 21.92.23.8-1.9-1.5-0.9-1.5-1.3-1.5-1.4-2.0-1.2-1.6-1.6-1.6-1.4-1.3-1.6-1.7-1.80.0
Vertical activity count, locomotor time 20.20.20.9-1.0-0.4-0.1-0.5-0.3-0.4-0.3-0.6-0.4-0.6-0.6-0.5-0.4-0.4-0.5-0.5-0.60.0
Light reinforcement 10.10.20.5-0.7-0.6-0.1-0.6-0.3-0.4-0.5-0.4-0.4-0.4-0.4-0.6-0.5-0.4-0.5-0.4-0.60.0
Light reinforcement 20.20.40.8-0.2-0.6-0.9-0.7-0.6-0.7-0.7-0.1-0.8-0.5-0.5-0.4-0.7-0.8-0.7-0.4-0.50.0
Bone: marrow area0.20.55.30.70.0-2.3-0.1-0.9-0.7-0.4-0.1-0.9-0.1-0.1-0.1-0.8-0.7-0.1-0.0-0.00.0
Bone: maximum diameter0.10.21.10.90.5-1.00.5-0.10.10.30.5-0.00.50.50.40.00.20.50.50.50.0
Bone: maximum force4.58.09.1-2.7-3.0-2.9-3.0-3.0-2.9-3.0-2.9-3.0-3.0-3.0-2.8-2.9-2.9-2.9-2.8-2.80.0
Bone: maximum moment3.96.87.9-2.4-2.7-2.8-2.7-2.8-2.7-2.7-2.6-2.8-2.7-2.7-2.6-2.7-2.7-2.7-2.6-2.60.0
Mean time between licks in bursts0.71.63.71.91.5-0.01.30.91.01.21.60.91.61.61.41.01.01.31.51.50.0
Mean num. licks in bursts0.40.61.2-0.9-0.90.4-0.8-0.4-0.4-0.8-0.9-0.4-1.1-1.1-0.8-0.5-0.4-0.9-0.9-0.80.0
Cd content in liver0.00.00.1-0.3-0.10.2-0.1-0.0-0.2-0.10.00.0-0.2-0.2-0.10.1-0.2-0.30.1-0.00.0
Co content in liver1.41.73.2-1.8-1.4-0.8-1.3-1.2-1.2-1.2-1.5-1.2-1.4-1.4-1.3-1.2-1.1-1.3-1.4-1.60.0
Cu content in liver0.70.82.90.30.71.70.81.11.10.80.51.21.01.00.61.01.10.80.70.60.0
Fe content in liver1.11.32.1-1.4-1.3-0.6-1.3-1.0-1.1-1.2-1.0-1.2-1.3-1.3-1.2-1.1-1.2-1.2-1.3-1.30.0
K content in liver0.10.10.2-0.20.00.50.10.30.50.1-0.10.20.10.10.10.10.30.4-0.1-0.30.0
Mg content in liver1.71.72.41.31.41.01.41.31.51.41.11.21.61.61.21.21.41.61.31.20.0
Mn content in liver4.24.76.62.62.41.22.42.02.32.32.12.02.52.52.32.02.22.52.22.20.0
Na content in liver0.80.82.1-1.4-1.1-0.4-1.0-0.7-0.6-0.9-1.3-0.9-0.8-0.8-0.9-0.8-0.8-0.7-1.2-1.10.0
Rb content in liver1.01.11.90.81.11.31.01.11.21.11.01.11.11.11.01.11.21.41.00.90.0
Se content in liver1.31.52.61.61.40.21.41.01.11.31.30.91.51.51.41.11.11.41.31.30.0
Sr content in liver0.20.20.7-0.2-0.4-0.9-0.3-0.5-0.5-0.4-0.4-0.6-0.4-0.4-0.3-0.5-0.5-0.3-0.4-0.30.0
Zn content in liver0.10.10.30.40.40.10.40.30.30.30.40.30.30.30.30.30.40.50.40.30.0
Bone: minimum diameter0.10.31.11.10.6-1.10.4-0.00.00.30.6-0.10.40.40.60.00.10.40.60.50.0
Time in familiar zone, hab. session 10.90.94.20.50.72.10.81.31.10.90.71.20.50.50.91.21.00.70.70.70.0
Time in novel zone, hab. session 10.30.32.3-0.1-0.3-1.5-0.4-0.8-0.6-0.5-0.3-0.8-0.2-0.2-0.4-0.7-0.5-0.3-0.3-0.30.0
Total zone transitions, hab. session 10.50.70.90.80.90.90.80.90.90.90.80.90.90.90.80.90.90.80.80.80.0
Total locomotion distance, hab. session 10.20.30.60.40.50.80.60.60.60.60.60.70.50.50.50.70.60.50.50.50.0
Locomotion velocity, hab. session 10.00.00.2-0.00.10.40.20.20.20.30.20.30.10.10.10.30.30.10.10.10.0
Time in familiar zone, hab. session 20.00.00.20.00.00.50.10.20.10.10.20.2-0.1-0.10.00.20.10.00.10.10.0
Time in novel zone, hab. session 20.10.10.2-0.3-0.4-0.5-0.4-0.4-0.3-0.4-0.5-0.5-0.3-0.3-0.3-0.4-0.4-0.4-0.4-0.40.0
Total zone transitions, hab. session 20.00.00.2-0.4-0.20.1-0.2-0.1-0.2-0.1-0.2-0.1-0.1-0.1-0.3-0.1-0.2-0.2-0.2-0.20.0
Total locomotion distance, hab. session 20.50.71.50.50.71.20.80.90.81.00.91.00.60.60.71.00.90.80.70.80.0
Locomotion velocity, hab. session 20.60.81.60.60.81.30.91.00.91.10.91.10.80.80.81.01.00.90.80.90.0
Novel to familiar place preference ratio0.10.10.3-0.4-0.3-0.0-0.2-0.1-0.1-0.2-0.5-0.1-0.1-0.1-0.3-0.2-0.0-0.2-0.3-0.30.0
Novelty place preference0.10.10.4-0.5-0.4-0.3-0.4-0.3-0.3-0.3-0.6-0.3-0.2-0.2-0.5-0.4-0.2-0.3-0.4-0.50.0
Time in novel zone, NPP test0.20.20.4-0.6-0.5-0.5-0.5-0.4-0.4-0.4-0.7-0.4-0.3-0.3-0.5-0.5-0.4-0.4-0.5-0.50.0
Total zone transitions, NPP test0.91.31.81.11.21.31.21.31.21.21.11.21.21.21.11.21.21.11.11.20.0
Total locomotion distance, NPP test0.50.61.70.50.71.30.80.90.90.90.71.00.60.60.70.90.90.70.70.70.0
Locomotion velocity, NPP test1.01.43.10.81.01.81.11.31.31.21.01.41.01.01.01.31.31.11.01.10.0
Intraocular pressure0.60.81.21.10.81.10.91.01.00.80.41.10.70.70.91.01.00.71.11.00.0
Delta distance traveled before/after self-admin2.12.23.9-1.4-1.5-1.7-1.5-1.4-1.6-1.5-0.8-1.4-2.0-2.0-1.1-1.5-1.5-1.4-1.3-1.3-1.5
Delta ambulatory time before/after self-admin1.21.53.6-1.0-1.1-1.4-1.2-1.1-1.4-1.1-0.4-1.2-1.9-1.9-0.7-1.2-1.3-1.1-0.9-1.0-1.1
Parametrial fat weight1.12.63.4-1.3-1.7-1.9-1.7-1.8-1.7-1.8-1.7-1.6-1.5-1.5-1.7-1.7-1.5-1.6-1.8-1.70.0
Pavlov. Cond. lever latency2.12.64.4-2.1-1.9-0.5-1.7-1.4-1.5-1.6-1.9-1.3-2.0-2.0-1.8-1.4-1.4-1.7-1.8-1.70.0
Pavlov. Cond. magazine entry latency2.83.65.62.42.21.02.01.71.82.02.31.72.02.02.11.81.72.02.22.10.0
Pavlov. Cond. change in total contacts0.10.10.60.60.3-0.80.2-0.1-0.00.10.4-0.20.40.40.3-0.1-0.10.20.30.20.0
Pavlov. Cond. index score3.34.16.62.62.30.92.21.81.92.12.41.82.22.22.31.91.82.12.32.20.0
Pavlov. Cond. latency score2.53.25.32.32.10.61.91.51.61.82.21.52.02.02.01.61.51.92.01.90.0
Pavlov. Cond. lever contacts1.72.03.61.91.70.31.51.21.31.41.81.11.61.61.71.21.21.61.61.50.0
Pavlov. Cond. magazine entry number3.54.46.0-2.4-2.3-1.4-2.3-2.0-2.0-2.2-2.5-2.0-2.1-2.1-2.3-2.1-2.0-2.2-2.3-2.30.0
Pavlov. Cond. intertrial magazine entries0.10.10.7-0.5-0.30.8-0.30.10.0-0.3-0.30.1-0.2-0.2-0.30.00.0-0.3-0.3-0.30.0
Pavlov. Cond. lever-magazine prob. diff.3.64.56.92.62.41.12.31.92.02.12.51.92.32.32.42.01.92.22.42.30.0
Pavlov. Cond. response bias3.84.77.12.72.41.22.32.02.12.22.52.02.32.32.42.12.02.22.42.30.0
Pavlov. Cond. lever latency0.10.20.7-0.2-0.3-0.8-0.4-0.5-0.5-0.5-0.5-0.5-0.3-0.3-0.4-0.5-0.4-0.4-0.4-0.40.0
Pavlov. Cond. magazine entry latency0.10.20.7-0.2-0.4-0.8-0.4-0.5-0.5-0.4-0.2-0.5-0.3-0.3-0.4-0.5-0.5-0.3-0.3-0.30.0
Pavlov. Cond. change in total contacts0.20.30.6-0.8-0.6-0.2-0.5-0.5-0.5-0.4-0.5-0.6-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.60.0
Pavlov. Cond. index score0.00.00.00.10.0-0.00.00.0-0.00.10.20.00.10.10.10.1-0.00.00.10.10.0
Pavlov. Cond. latency score0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.1-0.2-0.1-0.1-0.2-0.2-0.3-0.2-0.2-0.20.0
Pavlov. Cond. lever contacts0.00.10.30.00.10.60.20.30.20.30.40.30.10.10.30.30.20.20.20.20.0
Pavlov. Cond. magazine entry number0.20.30.50.40.50.70.50.60.60.50.40.60.50.50.50.50.60.50.40.40.0
Pavlov. Cond. intertrial magazine entries1.82.84.22.01.91.21.81.61.61.71.51.61.91.91.71.61.61.71.81.80.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.20.10.00.10.10.00.10.20.10.10.10.10.10.00.10.20.10.0
Pavlov. Cond. response bias0.20.20.50.50.40.40.50.50.40.50.70.50.40.40.50.50.40.50.50.50.0
Time in closed arm before self-admin0.10.10.30.00.20.40.30.40.40.40.50.20.50.50.30.30.30.40.20.00.1
Time in closed arm after self-admin1.11.22.4-1.5-1.1-0.7-1.1-1.2-0.9-1.0-1.1-1.1-1.0-1.0-1.5-1.1-1.0-0.9-1.1-1.1-0.6
Time in open arm before self-admin0.60.61.41.00.90.50.80.60.70.70.90.80.70.70.80.80.80.61.01.20.7
Time in open arm after self-admin0.50.51.61.30.80.40.70.60.40.60.40.70.70.70.90.70.50.30.90.90.7
Bone: periosteal estimation0.71.56.2-0.4-0.9-2.5-1.0-1.6-1.5-1.2-0.9-1.6-0.9-0.9-0.9-1.5-1.4-1.0-0.9-0.90.0
Bone: periosteal perimeter0.10.21.60.3-0.0-1.3-0.1-0.5-0.4-0.20.1-0.5-0.0-0.0-0.0-0.4-0.4-0.10.0-0.00.0
Bone: post-yield work1.11.63.61.91.50.21.31.01.11.21.50.91.31.31.51.11.01.31.41.40.0
Progressive ratio test 1 active lever presses0.20.20.6-0.3-0.3-0.1-0.3-0.6-0.8-0.5-0.7-0.1-0.0-0.0-0.7-0.4-0.3-0.6-0.5-0.60.3
Progressive ratio test 1 breakpoint0.20.20.7-0.4-0.4-0.2-0.4-0.7-0.8-0.5-0.7-0.2-0.1-0.1-0.7-0.5-0.4-0.7-0.5-0.60.2
Progressive ratio test 1 inactive lever presses0.30.41.0-1.0-0.60.0-0.6-0.5-0.6-0.6-0.5-0.3-0.5-0.5-0.7-0.6-0.4-0.6-0.9-0.8-0.4
Progressive ratio test 2 active lever presses0.10.10.30.10.30.40.20.0-0.10.00.00.40.30.3-0.10.10.2-0.20.10.10.6
Progressive ratio test 2 breakpoint0.00.00.20.10.20.30.1-0.0-0.2-0.0-0.00.30.20.2-0.10.10.1-0.30.10.00.5
Progressive ratio test 2 inactive lever presses0.20.41.2-0.2-0.3-1.1-0.4-0.8-0.9-0.6-0.6-0.4-0.5-0.5-0.7-0.7-0.4-0.8-0.6-0.30.6
Incentive Sensitization - Responses0.40.61.00.70.80.60.80.80.60.71.00.90.50.50.80.80.80.50.70.90.7
Incentive Sensitization - Breakpoint0.40.51.00.70.80.60.80.80.70.71.00.90.50.50.80.80.80.50.70.90.7
Sum of active levers in priming session hrs 5-60.60.51.40.50.70.50.60.80.60.70.90.70.70.70.90.80.60.60.81.2-0.3
Progressive ratio5.48.59.9-2.6-3.1-3.0-2.9-3.0-3.1-3.0-3.1-2.8-2.9-2.9-2.9-3.0-2.9-3.0-3.1-2.6-2.5
Food seeking constrained by brief footshock0.00.00.10.1-0.00.20.10.20.30.10.20.2-0.3-0.3-0.00.20.30.3-0.00.0-0.1
Seeking ratio, punishment vs. effort4.66.78.72.12.62.82.72.72.92.72.92.52.32.32.62.72.72.82.62.32.2
Retroperitoneal fat weight0.52.02.6-1.2-1.5-1.6-1.5-1.5-1.6-1.6-1.5-1.4-1.3-1.3-1.6-1.5-1.5-1.4-1.3-1.30.0
Reaction time number correct0.50.92.4-1.5-1.10.2-1.0-0.7-0.6-0.9-0.8-0.9-1.2-1.2-1.0-0.8-0.8-0.8-1.3-1.20.0
Reaction time mean minus median0.81.96.82.61.60.11.41.01.01.11.21.01.61.61.61.10.91.11.81.60.0
Reaction time mean minus median AUC0.61.64.92.21.50.41.31.00.91.11.20.91.51.51.61.20.91.01.61.50.0
Reaction time num false alarms0.20.20.5-0.5-0.5-0.5-0.5-0.5-0.7-0.4-0.4-0.6-0.2-0.2-0.5-0.6-0.6-0.5-0.5-0.50.0
Reaction time num false alarms AUC0.30.40.8-0.7-0.7-0.8-0.6-0.7-0.9-0.6-0.6-0.8-0.4-0.4-0.7-0.8-0.8-0.7-0.7-0.70.0
Reaction time trials correct on left0.50.92.4-1.5-1.10.2-1.0-0.7-0.6-0.9-0.8-0.9-1.2-1.2-1.0-0.8-0.8-0.8-1.3-1.20.0
Reaction time trials on left0.50.92.2-1.5-1.10.1-1.0-0.7-0.6-0.9-0.8-0.9-1.2-1.2-1.0-0.8-0.8-0.8-1.3-1.10.0
Reaction time mean2.03.27.22.72.00.71.81.51.41.62.01.42.22.22.01.51.31.72.12.00.0
Reaction time mean AUC2.03.17.52.72.00.71.81.51.41.62.01.42.22.22.01.51.31.62.22.00.0
Median of all reaction times1.62.34.42.11.70.61.51.31.31.41.91.21.91.91.71.31.11.51.71.60.0
Reaction time omissions1.11.64.62.21.50.41.40.80.91.10.91.01.61.61.31.10.91.11.61.60.0
Reaction time false alarm rate0.10.10.60.30.1-0.70.1-0.2-0.40.1-0.0-0.20.40.40.0-0.2-0.2-0.00.20.10.0
Reaction time premature initiation rate1.52.12.8-1.5-1.6-1.5-1.5-1.6-1.4-1.5-1.7-1.5-1.3-1.3-1.5-1.6-1.4-1.4-1.6-1.50.0
Reaction time premature initiations2.23.95.7-2.4-2.2-1.5-2.0-2.0-1.8-1.9-2.2-2.0-2.0-2.0-2.1-2.0-1.8-1.9-2.3-2.20.0
Std. dev. reaction times0.91.76.12.51.50.01.30.80.71.11.30.91.71.71.51.00.71.01.71.60.0
Reaction time trials completed0.50.92.2-1.5-1.10.1-1.0-0.7-0.6-0.9-0.8-0.9-1.2-1.2-1.0-0.8-0.8-0.8-1.3-1.10.0
Reaction time trials AUC0.40.82.1-1.4-1.00.2-0.9-0.7-0.5-0.8-0.7-0.8-1.1-1.1-0.9-0.7-0.7-0.8-1.2-1.00.0
Run reversals in cocaine runway, females0.20.20.4-0.5-0.4-0.3-0.4-0.4-0.3-0.4-0.6-0.2-0.5-0.5-0.6-0.3-0.2-0.4-0.2-0.3-0.4
Run reversals in cocaine runway, males0.30.31.70.8-0.0-1.3-0.1-0.7-0.6-0.4-0.2-0.5-0.2-0.2-0.2-0.5-0.4-0.4-0.00.20.7
Latency to leave start box in cocaine runway0.20.20.70.10.40.30.50.40.40.50.50.3-0.5-0.50.50.30.40.60.20.50.8
Latency to leave start box in cocaine runway, F0.50.61.10.40.70.80.90.80.90.90.90.70.00.00.80.80.81.10.70.80.9
Latency to leave start box in cocaine runway, M0.70.71.6-0.8-0.8-0.9-0.8-0.7-0.8-0.8-0.6-0.8-1.3-1.3-0.5-0.9-0.8-0.8-0.9-0.7-0.2
Std. dev. time between licks in bursts0.70.91.81.31.1-0.41.10.60.71.01.30.51.11.11.10.70.71.21.21.10.0
Total sessions with >9 infusions0.50.61.4-0.6-0.6-0.8-0.7-1.0-1.0-0.9-1.2-0.6-0.6-0.6-0.9-0.9-0.7-1.0-0.7-0.8-0.0
Short access day 1 total inactive lever presses0.91.23.0-0.4-0.8-1.7-1.0-1.6-1.4-1.2-0.7-1.3-0.7-0.7-1.1-1.4-1.3-1.1-1.1-0.80.2
Short access day 10 total inactive lever presses0.20.51.30.70.70.20.70.90.70.61.00.60.60.60.90.50.60.60.30.51.1
Short access day 1 total infusions0.00.10.30.10.1-0.10.0-0.3-0.3-0.1-0.30.20.20.2-0.3-0.1-0.1-0.20.0-0.00.6
Short access day 10 total infusions0.40.51.1-0.4-0.5-0.7-0.7-0.9-0.9-0.8-1.0-0.4-0.5-0.5-1.0-0.7-0.7-1.0-0.5-1.0-0.0
Short access total infusions0.70.81.7-0.6-0.7-0.8-0.8-1.2-1.3-1.0-1.3-0.6-0.6-0.6-1.2-1.0-0.9-1.2-0.8-0.90.1
Short access day 1 locomotion1.41.73.01.21.41.11.31.31.11.21.31.51.51.51.31.21.21.11.31.21.7
Short access day 10 total locomotion0.10.10.6-0.10.0-0.8-0.1-0.2-0.3-0.10.1-0.50.40.40.2-0.3-0.50.0-0.1-0.50.2
Short access total locomotion0.10.20.80.20.3-0.30.30.0-0.00.20.10.10.90.90.20.00.00.20.1-0.10.9
One hour access (0.3 mA shock)1.11.32.01.21.30.81.21.20.91.11.11.40.80.81.11.21.30.91.11.21.2
Compulsive drug intake4.85.77.12.22.51.82.62.52.32.52.72.32.22.22.52.42.52.62.12.42.5
One hour access (shock baseline)0.50.81.7-0.4-0.8-0.9-0.9-1.0-1.0-1.1-1.0-0.6-1.0-1.0-1.0-0.8-0.8-1.3-0.6-0.6-1.0
Social response proportion0.00.00.10.20.2-0.40.1-0.0-0.10.1-0.0-0.10.10.10.1-0.00.00.00.30.10.0
Social responses0.20.20.4-0.5-0.5-0.5-0.4-0.5-0.5-0.3-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.2-0.60.0
Social time0.60.82.41.51.2-0.41.10.60.60.90.70.50.90.91.20.60.71.01.01.00.0
Soleus weight0.30.72.11.41.0-1.01.00.30.40.90.80.41.01.01.00.40.61.10.90.90.0
Bone: stiffness1.11.72.2-1.3-1.4-1.0-1.5-1.3-1.2-1.4-1.3-1.4-1.5-1.5-1.3-1.3-1.3-1.5-1.3-1.40.0
Tibialis anterior weight0.20.81.8-1.4-1.1-0.2-1.0-0.7-0.6-0.9-1.1-0.7-1.0-1.0-1.1-0.8-0.7-0.8-1.0-1.10.0
Time to tail flick, vehicle, before self-admin1.21.22.01.21.11.01.21.21.11.11.41.20.90.91.41.21.21.10.90.80.9
Time to tail flick, vehicle, after self-admin1.01.32.01.41.20.71.31.01.01.21.11.11.11.11.21.11.11.21.21.41.3
Time to tail flick, test, before self-admin0.00.00.10.30.2-0.10.20.30.20.10.10.30.00.00.10.20.20.10.30.20.1
Time to tail flick, test, after self-admin0.70.71.51.20.80.90.70.90.80.70.90.80.90.90.90.90.80.51.01.10.3
Delta time to tail flick, vehicle, before/after SA0.00.00.20.10.10.20.10.0-0.00.1-0.20.2-0.2-0.2-0.20.10.20.00.10.40.4
Delta time to tail flick, test, before/after SA0.20.31.20.20.31.10.40.60.50.40.60.40.50.50.60.50.40.30.30.4-0.0
Tibia length0.82.36.6-0.6-1.3-2.6-1.4-2.0-1.8-1.5-1.3-1.9-1.3-1.3-1.4-1.7-1.8-1.3-1.1-1.30.0
Ambulatory time before self-admin0.10.10.60.40.0-0.6-0.0-0.3-0.3-0.2-0.8-0.10.50.5-0.2-0.2-0.2-0.3-0.1-0.10.6
Ambulatory time after self-admin0.91.13.1-0.3-0.9-1.7-0.9-1.1-1.3-1.0-0.8-1.0-1.4-1.4-0.6-1.1-1.1-0.9-0.8-0.8-0.6
Bone: tissue strength4.54.56.1-2.0-2.2-2.5-2.2-2.3-2.1-2.3-2.3-2.3-2.1-2.1-2.1-2.3-2.1-2.1-2.1-2.20.0
Total heroin consumption0.10.10.30.60.2-0.10.20.2-0.00.10.40.2-0.0-0.00.40.10.10.20.20.50.1
Bone: trabecular number0.40.72.40.50.71.50.71.11.00.80.71.10.60.60.71.01.00.70.70.70.0
Bone: trabecular spacing2.22.95.6-1.4-1.6-2.4-1.6-2.0-1.9-1.7-1.6-2.0-1.5-1.5-1.6-1.9-1.9-1.6-1.6-1.60.0
Bone: trabecular thickness0.50.72.00.60.71.40.71.00.90.70.81.00.70.70.81.00.90.50.70.80.0
Bone: trabecular tissue density1.52.33.0-1.5-1.6-1.4-1.6-1.6-1.7-1.5-1.4-1.6-1.6-1.6-1.4-1.5-1.7-1.6-1.5-1.40.0
Water consumed over 24 hours0.00.00.00.00.1-0.10.10.00.10.1-0.10.0-0.2-0.20.10.00.20.10.10.00.0
Number of responses in last shaping day0.30.30.8-0.6-0.4-0.8-0.4-0.7-0.9-0.4-0.9-0.6-0.2-0.2-0.5-0.7-0.7-0.5-0.4-0.60.4