Mdc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Mdc1 0.11 0.06 2.0e-10 0.08 0.09 0.08 0.08 4.6e-09 5.5e-10 3.6e-09 1.6e-09
2 Adipose alternative TSS XM_039098647.1 0.03 0.02 2.6e-03 0.01 0.01 0 0 2.9e-02 2.4e-02 1.9e-01 1.1e-01
3 pVTA mRNA stability Mdc1 0.14 0.1 1.3e-04 0.04 0.06 0.03 0.03 5.4e-03 1.2e-03 1.3e-02 1.3e-02
4 NAcc mRNA stability Mdc1 0.04 0.03 1.4e-04 0.03 0.03 0.02 0.03 2.3e-04 2.1e-04 1.6e-03 5.9e-04
5 PL gene expression Mdc1 0.27 0.09 0.0e+00 0.33 0.33 0.34 0.34 3.8e-37 2.7e-37 1.5e-38 6.8e-38
6 BLA gene expression Mdc1 0.53 0.15 0.0e+00 0.24 0.32 0.33 0.33 4.0e-13 1.2e-17 4.7e-18 4.4e-18
7 Adipose gene expression Mdc1 0.72 0.09 0.0e+00 0.66 0.68 0.7 0.7 4.2e-98 5.1e-103 3.7e-109 5.9e-109
8 pVTA gene expression Mdc1 0.36 0.12 0.0e+00 0.27 0.22 0.29 0.17 5.3e-12 5.5e-10 7.4e-13 7.5e-08
9 Liver mRNA stability Mdc1 0.12 0.07 1.3e-13 0.11 0.11 0.1 0.12 2.9e-12 2.0e-12 1.7e-11 3.6e-13
10 Liver gene expression Mdc1 0.54 0.13 0.0e+00 0.48 0.52 0.51 0.51 1.5e-60 7.3e-67 9.7e-66 1.4e-65
11 Brain gene expression Mdc1 0.36 0.1 0.0e+00 0.35 0.41 0.4 0.38 7.6e-34 1.7e-40 2.2e-39 1.8e-37
12 NAcc gene expression Mdc1 0.3 0.13 0.0e+00 0.33 0.32 0.33 0.33 7.9e-39 2.0e-37 1.2e-38 9.0e-39
13 Adipose mRNA stability Mdc1 0.42 0.15 0.0e+00 0.39 0.37 0.39 0.4 5.9e-46 4.4e-43 5.9e-46 1.2e-47
14 Adipose isoform ratio XM_039098643.1 0.03 0.03 1.1e-03 0.01 0.01 0.01 0.01 9.5e-03 1.1e-02 2.4e-02 2.0e-02
15 BLA mRNA stability Mdc1 0.08 0.05 9.3e-04 0.06 0.05 0.04 0.05 5.0e-04 1.3e-03 3.0e-03 1.2e-03
16 Brain mRNA stability Mdc1 0.12 0.07 2.5e-10 0.11 0.1 0.1 0.11 2.8e-10 5.8e-10 1.3e-09 2.0e-10
17 LHb gene expression Mdc1 0.21 0.14 1.3e-03 0.03 0.01 0.03 0.01 5.6e-02 1.9e-01 5.5e-02 2.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.61.13.5-0.20.10.50.5-1.21.2-0.9-1.21.31.21.4-0.90.9-0.8-0.71.1-1.9
Area under the delay curve2.42.53.5-1.3-1.4-1.7-1.41.6-1.71.41.6-1.7-1.7-1.71.6-1.41.91.8-1.41.5
BMI with tail2.16.87.8-2.0-2.4-2.6-2.62.8-2.72.72.7-2.4-2.7-2.72.6-2.72.62.7-2.62.7
BMI without tail3.06.28.4-1.3-1.9-2.2-2.32.7-2.82.52.8-2.4-2.8-2.92.5-2.52.62.5-2.42.8
Body weight4.920.730.1-1.8-3.0-3.6-4.05.1-5.24.75.2-4.7-5.0-5.44.5-4.64.54.5-4.55.5
Weight adjusted by age2.12.43.9-0.3-0.8-1.2-1.21.6-1.81.61.8-1.7-1.8-1.91.7-1.51.51.5-1.52.0
Bone surface0.00.00.10.30.20.00.00.1-0.3-0.00.2-0.1-0.2-0.30.1-0.10.20.30.20.2
Bone volume0.10.10.3-0.4-0.5-0.4-0.50.2-0.40.30.4-0.2-0.4-0.30.4-0.40.50.5-0.1-0.1
Breakpoint value in progressive ratio session1.01.11.70.60.80.91.1-1.21.1-1.2-0.91.01.11.1-1.00.9-1.0-0.81.3-1.1
Number of licking bursts0.80.91.61.31.31.11.2-0.90.8-1.1-0.90.80.80.7-1.01.0-0.9-0.81.0-0.6
Context. condit. distance diff. score9.311.212.93.43.53.63.5-3.33.3-3.4-3.23.33.33.1-3.53.4-3.5-3.53.3-2.6
Locomotion velocity, session 10.40.40.70.90.80.80.7-0.60.6-0.5-0.60.70.60.6-0.70.7-0.6-0.60.5-0.5
Locomotion distance, session 10.10.10.5-0.7-0.5-0.2-0.2-0.30.3-0.0-0.30.30.20.4-0.00.00.10.10.1-0.7
Locomotion velocity, session 20.10.10.30.50.40.40.4-0.30.1-0.4-0.20.30.20.1-0.30.3-0.2-0.20.5-0.1
Locomotion distance, session 20.20.30.60.10.20.40.3-0.70.6-0.5-0.70.70.60.6-0.50.5-0.4-0.40.6-0.8
Locomotion velocity, session 30.30.40.8-0.9-0.8-0.7-0.70.6-0.50.70.4-0.5-0.4-0.30.6-0.60.60.6-0.80.2
Locomotion distance, session 31.21.32.00.50.71.00.9-1.21.2-1.1-1.31.31.31.4-1.11.2-1.1-1.11.1-1.4
Stereotopy head waving bouts, day 30.50.61.40.40.0-0.3-0.40.9-1.00.61.0-0.9-1.0-1.20.7-0.70.70.6-0.61.1
Stereotopy head waving duration, day 30.50.61.40.1-0.2-0.4-0.51.0-1.00.80.9-0.9-0.9-1.10.7-0.70.70.7-0.91.2
Locomotion velocity, session 74.24.65.71.31.72.01.9-2.32.3-2.2-2.42.42.32.4-2.22.2-2.1-2.12.2-2.4
Locomotion distance, session 73.24.05.70.71.21.51.7-2.32.2-2.2-2.22.22.22.3-1.92.0-2.0-2.02.2-2.4
Stereotopy head waving bouts, day 71.71.92.9-0.7-1.0-1.2-1.31.4-1.51.41.7-1.6-1.5-1.61.4-1.51.41.4-1.21.3
Stereotopy head waving duration, day 72.02.43.6-0.6-1.0-1.2-1.41.7-1.81.61.9-1.7-1.7-1.81.6-1.71.61.6-1.41.6
Locomotion velocity, session 81.92.36.82.62.32.01.8-1.31.0-1.6-0.91.11.00.6-1.51.4-1.4-1.41.6-0.5
Locomotion distance, session 85.07.38.42.62.72.92.8-2.92.6-2.9-2.62.82.72.5-2.82.7-2.7-2.72.9-2.3
Degree of sensitization distance0.80.81.21.01.10.91.1-0.90.8-1.1-0.80.80.80.7-0.90.9-0.9-0.91.0-0.4
Degree of sensitization stereotypy1.11.21.9-0.7-0.9-1.0-1.11.0-1.31.01.4-1.3-1.2-1.31.1-1.31.21.2-0.80.9
Conditioned locomotion0.30.30.80.2-0.1-0.3-0.30.7-0.70.60.5-0.5-0.6-0.80.5-0.30.50.6-0.50.9
Cocaine response after cond. corrected0.30.30.50.10.30.30.5-0.70.6-0.7-0.70.60.60.7-0.60.6-0.5-0.50.7-0.7
Cocaine response after cond. not corrected0.10.10.40.60.50.20.4-0.1-0.1-0.3-0.0-0.0-0.1-0.2-0.20.2-0.1-0.00.30.3
Cocaine response before conditioning2.02.44.90.2-0.4-0.9-1.01.8-1.91.41.9-1.9-1.9-2.21.4-1.41.41.5-1.32.2
Saline control response2.33.04.1-1.9-2.0-1.8-2.01.8-1.62.01.5-1.6-1.6-1.41.7-1.81.81.8-2.01.2
Bone: connectivity density2.23.45.10.91.31.61.6-2.02.0-1.7-2.12.22.02.2-1.91.9-1.8-1.71.7-2.3
Bone: cortical apparent density1.62.24.0-2.0-1.9-1.7-1.71.4-1.21.61.1-1.3-1.2-1.01.5-1.41.51.6-1.60.8
Bone: cortical area1.92.84.0-1.0-1.3-1.6-1.61.6-2.01.51.9-1.7-1.9-2.01.8-1.81.81.9-1.21.6
Bone: cortical porosity0.80.91.2-1.0-1.0-1.1-1.00.9-0.90.90.9-1.0-1.0-0.91.0-1.01.01.0-0.80.7
Bone: cortical porosity0.30.40.7-0.1-0.3-0.5-0.50.6-0.70.50.7-0.8-0.7-0.80.6-0.60.60.6-0.50.7
Bone: cortical thickness5.69.211.8-3.4-3.4-3.4-3.32.7-3.02.93.0-2.9-3.0-2.73.2-3.23.23.3-2.51.9
Bone: cortical thickness2.32.75.1-2.3-2.1-2.0-1.91.4-1.41.61.3-1.4-1.4-1.11.7-1.61.81.8-1.60.8
Bone: cortical tissue density1.31.73.2-1.8-1.7-1.5-1.51.3-1.11.41.0-1.2-1.1-0.91.3-1.31.41.4-1.50.7
Condit. Reinf. active minus inactive responses0.80.91.20.70.80.90.9-1.01.0-0.9-1.11.11.01.0-1.01.1-0.9-0.90.9-1.0
Condit. Reinf. active-inactive response ratio0.10.10.3-0.5-0.5-0.4-0.30.2-0.20.30.2-0.2-0.2-0.20.3-0.20.30.4-0.30.1
Condit. Reinf. active responses1.11.32.10.60.81.01.0-1.21.3-1.1-1.51.41.31.3-1.11.3-1.1-1.11.0-1.2
Condit. Reinf. inactive responses1.11.32.30.20.40.90.8-1.21.4-1.1-1.51.41.41.5-1.11.2-1.1-1.11.0-1.5
Incentive salience index mean2.73.23.81.81.91.91.8-1.91.7-1.9-1.81.91.71.6-1.81.9-1.8-1.82.0-1.5
Condit. Reinf. lever presses4.66.27.32.62.62.72.6-2.52.4-2.7-2.52.62.42.2-2.52.5-2.4-2.52.7-1.8
Condit. Reinf. active minus inactive responses0.81.01.6-0.3-0.6-0.9-0.81.1-1.10.91.1-1.2-1.2-1.31.0-1.01.01.0-0.91.2
Condit. Reinf. active-inactive response ratio1.41.52.7-0.2-0.5-0.9-0.91.3-1.41.11.4-1.4-1.5-1.61.2-1.11.21.2-1.01.6
Condit. Reinf. active responses0.00.00.00.10.10.10.10.00.1-0.0-0.10.00.00.0-0.10.1-0.1-0.1-0.10.0
Condit. Reinf. inactive responses1.11.32.20.50.81.11.0-1.11.4-0.9-1.41.31.41.5-1.21.2-1.2-1.20.7-1.2
Condit. Reinf. lever presses0.30.40.70.30.50.50.6-0.60.8-0.6-0.80.70.70.7-0.60.7-0.6-0.70.4-0.5
Condit. Reinf. lever reinforcers received0.10.10.10.30.30.30.3-0.20.3-0.2-0.30.20.30.2-0.30.3-0.3-0.30.1-0.1
Conditioned reinforcement - actives0.50.51.0-0.5-0.6-0.8-0.50.6-0.70.50.6-0.9-0.7-0.70.7-1.00.90.4-0.50.7
Conditioned reinforcement - inactives1.82.13.0-1.4-1.4-1.5-1.41.3-1.51.41.2-1.7-1.4-1.31.5-1.51.71.5-1.21.2
Conditioned locomotion0.00.00.20.20.20.10.2-0.0-0.1-0.0-0.0-0.2-0.0-0.10.1-0.20.1-0.5-0.10.1
Patch foraging indifference point 0 sec1.11.83.5-1.9-1.8-1.6-1.61.2-1.21.41.0-1.4-1.2-0.91.2-1.41.41.6-1.10.4
Patch foraging indifference point AUC1.82.12.9-0.7-1.0-1.2-1.31.6-1.61.51.5-1.6-1.6-1.71.6-1.41.61.6-1.31.6
Delay disc. indifference point, 0s delay0.10.20.40.1-0.0-0.3-0.10.4-0.70.20.4-0.5-0.5-0.60.50.00.40.4-0.20.5
Delay disc. indifference point, 16s delay3.23.25.3-2.3-2.2-2.2-2.01.7-1.61.61.2-1.9-1.7-1.51.8-1.62.12.0-1.51.3
Delay disc. indifference point, 2s delay1.51.72.9-0.4-0.6-1.1-0.81.3-1.61.21.7-1.4-1.4-1.61.3-1.11.41.4-1.21.7
Delay disc. indifference point, 24s delay0.90.91.2-1.0-1.0-1.1-0.90.9-0.90.80.9-1.1-0.9-0.90.9-0.91.11.0-0.70.9
Delay disc. indifference point, 4s delay1.81.93.1-0.3-0.7-1.0-1.01.5-1.81.11.6-1.6-1.6-1.71.5-1.11.41.5-1.21.8
Delay disc. indifference point, 8s delay0.40.40.7-0.6-0.6-0.7-0.60.7-0.70.60.7-0.7-0.7-0.70.8-0.50.80.7-0.50.5
Indifference point function ln k0.81.11.81.11.21.11.1-1.11.0-1.1-1.01.11.00.9-1.21.1-1.2-1.31.0-0.7
Indifference point function log k0.81.11.81.11.21.11.1-1.11.0-1.1-1.01.11.00.9-1.21.1-1.2-1.31.0-0.7
Patch foraging total patch changes 0 sec1.62.64.8-2.2-2.1-1.9-1.91.5-1.41.61.2-1.6-1.4-1.11.5-1.61.61.8-1.40.6
Patch foraging total patch changes 12 sec2.12.74.3-2.1-2.0-1.9-1.81.5-1.41.71.3-1.8-1.5-1.21.7-1.71.61.9-1.51.0
Patch foraging total patch changes 18 sec1.72.26.0-2.5-2.2-1.8-1.81.2-1.01.50.9-1.1-1.0-0.61.5-1.51.61.7-1.30.1
Patch foraging total patch changes 24 sec0.70.84.2-2.1-1.6-1.2-1.10.2-0.30.70.2-0.6-0.30.20.7-0.90.80.9-0.4-0.8
Patch foraging total patch changes 6 sec2.02.96.3-2.5-2.3-2.1-2.01.5-1.41.81.2-1.6-1.5-1.11.6-1.71.91.9-1.50.5
Patch foraging time to switch 0 sec0.10.10.9-0.9-0.6-0.4-0.3-0.00.20.3-0.10.00.20.40.0-0.30.10.2-0.4-0.4
Patch foraging water rate 0 sec0.40.60.9-0.7-0.8-0.9-0.90.9-0.90.70.9-0.8-0.9-0.90.9-0.70.60.6-0.70.8
Patch foraging water rate 12 sec0.10.10.6-0.8-0.6-0.4-0.40.1-0.00.20.10.1-0.10.10.2-0.20.10.10.0-0.4
Patch foraging water rate 18 sec0.10.10.3-0.0-0.2-0.2-0.40.4-0.60.20.3-0.4-0.5-0.50.5-0.20.30.2-0.20.3
Patch foraging water rate 24 sec1.72.43.8-1.1-1.3-1.5-1.51.7-1.61.51.7-1.4-1.7-1.71.6-1.41.31.3-1.62.0
Patch foraging water rate 6 sec0.10.20.7-0.8-0.7-0.6-0.60.3-0.30.40.40.0-0.3-0.20.5-0.30.2-0.0-0.4-0.0
Seeking ratio, delayed vs. immediate footshock0.40.40.7-0.2-0.4-0.5-0.50.7-0.70.60.7-0.6-0.7-0.70.8-0.50.90.8-0.60.7
Distance traveled before self-admin0.30.30.90.90.80.70.6-0.40.4-0.5-0.30.40.40.3-0.40.6-0.5-0.50.4-0.2
Distance traveled after self-admin0.10.10.40.60.40.30.10.3-0.10.10.10.1-0.1-0.20.10.2-0.1-0.3-0.00.4
Extensor digitorum longus weight0.10.21.11.00.80.60.6-0.20.1-0.4-0.10.20.1-0.1-0.40.3-0.4-0.30.30.5
Bone: elastic displacement0.50.51.0-1.0-1.0-0.8-0.90.7-0.60.90.7-0.6-0.6-0.40.7-0.70.70.7-0.90.2
Bone: elastic work2.22.83.5-1.4-1.6-1.6-1.71.6-1.91.71.9-1.8-1.8-1.71.8-1.81.81.7-1.41.2
Bone: endosteal estimation0.51.25.12.31.40.70.60.9-0.90.31.0-0.7-0.8-1.40.2-0.20.20.1-0.52.3
Bone: endosteal perimeter1.22.49.53.12.62.12.0-0.90.9-1.4-0.81.00.90.4-1.41.5-1.4-1.51.20.5
Epididymis fat weight7.116.633.9-5.8-5.4-5.0-4.73.7-3.34.23.2-3.4-3.4-2.84.0-4.14.14.0-4.12.3
Delta time in closed arm before/after self-admin0.10.10.3-0.3-0.2-0.4-0.30.4-0.40.30.4-0.2-0.4-0.50.4-0.30.40.5-0.50.4
Delta time in open arm before/after self-admin0.10.00.2-0.2-0.3-0.1-0.30.2-0.20.20.1-0.2-0.1-0.10.1-0.20.30.5-0.20.0
Diff in mean of infusions in LGA sessions2.62.84.70.40.91.11.5-2.01.8-1.9-1.71.61.82.0-1.71.5-2.0-1.72.1-2.2
Delay discount exponential model param2.32.53.41.31.41.61.4-1.61.7-1.4-1.61.71.61.6-1.61.4-1.8-1.71.4-1.6
Extinction: sum of active levers before priming0.30.30.6-0.10.20.10.4-0.70.6-0.8-0.80.40.50.6-0.40.8-0.4-0.00.7-0.7
Active lever presses in extinction session 60.10.10.5-0.7-0.6-0.5-0.40.30.10.20.0-0.3-0.10.00.3-0.20.20.1-0.3-0.1
Bone: final force7.111.413.2-2.7-3.1-3.4-3.43.3-3.63.33.6-3.4-3.6-3.63.6-3.63.63.5-3.03.1
Bone: final moment6.210.111.9-2.5-2.9-3.2-3.23.2-3.43.13.4-3.2-3.4-3.43.4-3.33.43.3-2.82.9
Food consumed during 24 hour testing period0.10.20.50.70.30.2-0.10.5-0.50.30.5-0.3-0.4-0.60.2-0.20.20.3-0.30.7
Glucose4.06.013.43.73.42.93.0-2.21.9-2.6-1.92.02.01.5-2.52.5-2.4-2.42.6-0.7
Heart weight0.10.10.3-0.0-0.0-0.3-0.10.4-0.30.30.2-0.5-0.4-0.40.2-0.30.20.2-0.50.5
Delay discount hyperbolic model param2.22.33.11.11.21.51.3-1.61.7-1.4-1.61.71.61.7-1.51.3-1.8-1.71.4-1.6
Intermittent access intake day 1-15 change0.50.50.9-0.5-0.7-0.6-0.80.9-0.90.80.9-0.6-0.8-0.90.9-0.50.70.5-0.80.5
Intermittent access intake escalation0.10.10.20.40.10.2-0.10.3-0.40.10.5-0.1-0.2-0.40.20.00.1-0.1-0.20.2
Intermittent access intake escalation 21.01.03.51.91.51.41.1-0.60.6-1.0-0.40.70.70.3-0.81.1-1.1-1.10.9-0.2
Intermitt. access day 1 inactive lever presses0.10.10.40.60.50.20.30.1-0.0-0.1-0.0-0.2-0.1-0.3-0.00.2-0.00.10.00.6
Intermitt. access day 15 inactive lever presses2.52.73.8-1.0-1.3-1.5-1.51.8-1.61.81.5-1.8-1.7-1.81.7-1.61.81.9-1.62.0
Intermitt. access escalation Index2.82.53.31.01.31.51.6-1.81.7-1.6-1.51.41.81.8-1.81.6-1.8-1.31.5-1.6
Intermittent access day 1 total infusions0.20.20.7-0.00.20.30.5-0.70.5-0.4-0.50.30.60.7-0.50.10.0-0.10.6-0.8
Intermittent access day 15 total infusions0.00.00.3-0.2-0.10.10.1-0.2-0.0-0.10.10.10.10.20.0-0.00.2-0.10.2-0.5
Intermittent access terminal intake (last 3 days)0.10.10.3-0.4-0.4-0.4-0.30.2-0.40.30.4-0.5-0.3-0.30.4-0.40.50.3-0.20.1
Intermittent access total infusions0.00.00.1-0.3-0.3-0.2-0.1-0.1-0.10.10.1-0.1-0.0-0.00.2-0.40.40.10.0-0.2
Intermittent access day 1 locomotion0.30.30.70.80.70.80.8-0.70.4-0.6-0.40.30.60.6-0.70.4-0.1-0.20.8-0.6
Intermittent access day 15 total locomotion0.20.20.50.60.20.1-0.20.5-0.70.40.6-0.4-0.5-0.70.5-0.20.50.3-0.20.4
Intermittent access total locomotion0.10.10.40.60.20.2-0.10.3-0.50.20.6-0.3-0.3-0.50.3-0.30.50.2-0.10.4
Intermittent access standard deviation3.13.33.9-1.6-1.8-1.8-1.92.0-1.81.82.0-1.9-1.9-1.91.9-1.61.81.6-1.91.8
Left kidney weight3.59.812.7-1.6-2.3-2.6-2.83.5-3.43.23.6-3.5-3.4-3.53.0-3.33.03.1-3.23.6
Right kidney weight2.26.110.4-0.5-1.3-1.7-2.02.8-2.92.52.9-2.8-2.7-3.12.4-2.42.22.3-2.53.2
Cocaine induced anxiety4.14.75.92.32.32.42.2-2.22.2-2.1-2.12.22.22.0-2.22.1-2.2-2.32.2-1.9
Post-drug Anxiety1.61.82.91.41.41.41.3-1.21.4-1.2-1.41.31.31.2-1.41.2-1.4-1.71.1-0.8
Baseline Anxiety0.40.41.4-1.2-0.9-1.1-0.70.6-0.40.50.3-0.6-0.6-0.50.6-0.40.50.5-0.70.6
Tail length1.64.711.61.2-0.0-0.7-1.12.6-2.81.92.8-2.3-2.6-3.21.9-1.81.91.6-1.93.4
Length with tail2.07.515.90.4-0.8-1.4-1.93.2-3.42.73.3-3.0-3.2-3.72.6-2.62.42.3-2.64.0
Length without tail2.14.58.8-0.4-1.0-1.5-1.62.4-2.42.12.5-2.5-2.4-2.62.1-2.11.92.1-2.13.0
Times rat made contact with spout0.30.41.8-0.9-0.5-0.0-0.2-0.50.7-0.2-0.70.70.60.9-0.30.3-0.3-0.10.3-1.3
Lifetime Intake0.00.00.2-0.3-0.2-0.2-0.0-0.1-0.10.10.0-0.2-0.1-0.00.2-0.40.50.10.0-0.1
Liver weight, left0.10.21.31.10.70.60.30.2-0.40.10.3-0.2-0.2-0.4-0.10.00.10.40.10.6
Liver weight, right0.91.55.01.40.60.1-0.21.4-1.41.01.6-1.3-1.3-1.80.7-0.90.80.9-0.92.2
Locomotor activity0.30.42.91.71.10.80.40.4-0.50.20.5-0.4-0.3-0.7-0.30.0-0.1-0.3-0.21.0
Locomotor testing distance0.10.10.70.80.60.50.40.0-0.1-0.00.2-0.1-0.0-0.2-0.40.1-0.1-0.30.00.4
Locomotor testing rearing0.10.20.70.90.50.40.10.4-0.40.30.5-0.5-0.3-0.5-0.1-0.20.20.0-0.20.7
Locomotion in novel chamber0.60.71.2-0.4-0.6-0.6-0.70.9-1.11.01.0-0.9-0.9-0.90.9-0.70.60.9-0.70.9
Locomotion in novel chamber post-restriction0.80.91.1-0.9-1.0-1.0-1.01.1-1.11.01.0-0.9-1.0-1.01.0-0.91.00.8-1.01.0
Fecal boli incidents, locomotor time 10.60.71.10.50.70.80.8-1.01.0-0.8-0.81.00.91.0-0.90.7-0.9-0.80.7-0.7
Change in fecal boli incidents, locomotor task0.40.41.1-0.3-0.2-0.6-0.30.7-0.60.40.9-0.9-0.7-0.80.5-0.50.60.6-0.41.1
Time >=10cm from walls, locomotor time 10.20.20.70.90.60.30.20.2-0.10.10.3-0.3-0.2-0.4-0.1-0.50.20.3-0.10.7
Bouts of movement, locomotor time 11.92.12.71.51.51.71.4-1.41.4-1.5-1.51.51.51.4-1.41.6-1.4-1.41.3-1.4
Total resting periods, locomotor time 11.21.42.01.41.31.41.2-1.11.1-1.3-1.11.11.11.0-1.11.3-1.0-1.01.1-1.0
Rest time, locomotor task time 10.50.52.11.41.11.20.8-0.50.5-0.6-0.40.60.60.3-0.60.5-0.6-0.60.6-0.2
Distance moved, locomotor task time 11.11.21.6-1.2-1.2-1.3-1.21.1-1.11.10.9-1.1-1.1-1.01.1-1.01.01.0-1.10.9
Vertical activity count, locomotor time 10.70.81.3-1.0-1.0-1.0-1.00.8-0.80.90.8-0.9-0.8-0.70.7-0.90.60.8-1.10.6
Time >=10cm from walls, locomotor time 20.10.10.50.70.60.40.5-0.20.2-0.20.1-0.10.1-0.0-0.4-0.2-0.2-0.2-0.10.4
Bouts of movement, locomotor time 20.20.21.41.20.80.70.40.2-0.30.10.7-0.2-0.2-0.4-0.0-0.1-0.2-0.3-0.10.5
Total resting periods, locomotor time 20.40.52.71.61.21.10.8-0.20.0-0.30.40.20.2-0.1-0.40.4-0.6-0.70.30.2
Rest time, locomotor task time 22.12.47.02.62.32.21.8-1.21.2-1.4-1.01.41.30.9-1.61.5-1.6-1.41.3-0.5
Distance moved, locomotor task time 21.82.13.9-2.0-1.8-1.8-1.61.3-1.31.41.1-1.4-1.3-1.11.4-1.41.41.3-1.50.9
Vertical activity count, locomotor time 20.40.41.3-1.2-0.9-0.9-0.70.5-0.50.50.4-0.6-0.5-0.40.5-0.50.40.4-0.60.2
Light reinforcement 10.30.61.4-1.2-1.0-1.0-0.90.8-0.60.80.7-0.6-0.6-0.50.8-0.90.50.4-0.80.4
Light reinforcement 20.20.30.70.1-0.2-0.2-0.50.7-0.70.50.8-0.6-0.7-0.80.7-0.50.40.4-0.40.6
Bone: marrow area0.51.25.42.21.40.70.51.0-1.00.41.0-0.8-0.8-1.40.2-0.20.20.1-0.62.3
Bone: maximum diameter0.20.42.71.61.20.80.7-0.2-0.2-0.50.20.0-0.1-0.5-0.30.3-0.3-0.20.70.6
Bone: maximum force5.49.311.3-2.2-2.7-2.9-3.03.1-3.43.03.3-3.1-3.3-3.33.2-3.23.33.2-2.72.8
Bone: maximum moment4.78.110.1-1.9-2.5-2.7-2.82.9-3.22.83.1-2.9-3.1-3.13.0-3.03.03.0-2.52.7
Mean time between licks in bursts1.62.36.32.52.21.91.8-1.21.0-1.6-1.01.21.10.7-1.51.5-1.5-1.51.6-0.4
Mean num. licks in bursts0.60.72.5-1.6-1.4-1.0-1.20.6-0.50.90.5-0.4-0.5-0.20.8-0.70.70.7-0.9-0.1
Cd content in liver1.01.11.7-1.3-1.3-1.2-1.30.9-1.01.00.9-0.9-1.0-0.81.2-1.01.11.1-0.90.6
Co content in liver2.83.34.0-2.0-2.0-2.0-1.91.8-1.71.91.6-1.8-1.7-1.51.8-1.81.81.8-2.01.6
Cu content in liver1.01.23.2-0.7-0.10.40.5-1.21.5-0.8-1.41.31.31.7-1.00.9-1.0-1.00.8-1.8
Fe content in liver1.11.31.8-1.3-1.3-1.2-1.21.2-1.01.31.2-1.1-1.0-0.81.1-1.21.01.0-1.30.8
K content in liver0.20.20.40.20.30.20.4-0.50.4-0.6-0.60.30.40.4-0.30.5-0.3-0.30.6-0.4
Mg content in liver4.24.35.32.12.32.12.3-2.12.0-2.3-2.11.92.01.8-2.02.3-2.0-2.02.2-1.5
Mn content in liver4.34.99.93.13.02.62.7-1.91.9-2.2-1.91.91.91.5-2.22.4-2.3-2.32.0-0.8
Na content in liver0.20.20.3-0.6-0.5-0.6-0.4-0.0-0.40.00.4-0.3-0.4-0.30.5-0.40.50.50.3-0.1
Rb content in liver0.81.01.50.50.70.80.9-1.11.2-1.0-1.21.11.11.2-1.01.1-1.1-1.11.0-1.1
Se content in liver3.13.97.62.82.62.32.4-1.81.6-2.1-1.51.71.71.3-1.81.9-1.9-1.92.1-0.9
Sr content in liver0.20.20.60.50.3-0.00.10.3-0.50.20.5-0.5-0.4-0.60.4-0.30.40.4-0.20.8
Zn content in liver0.00.00.10.30.30.10.4-0.20.2-0.2-0.1-0.00.10.1-0.10.1-0.2-0.20.10.2
Bone: minimum diameter0.30.63.61.91.40.90.9-0.1-0.2-0.50.20.0-0.1-0.5-0.30.4-0.3-0.40.51.0
Time in familiar zone, hab. session 10.90.82.1-0.7-0.20.30.3-0.91.2-0.6-1.21.11.11.4-0.70.8-0.7-0.70.6-1.4
Time in novel zone, hab. session 10.40.31.00.80.50.10.00.7-0.70.40.7-0.7-0.6-0.90.3-0.30.30.3-0.51.0
Total zone transitions, hab. session 10.40.60.90.30.50.60.6-0.80.9-0.7-1.00.90.90.9-0.80.7-0.7-0.70.7-0.8
Total locomotion distance, hab. session 10.30.40.60.10.30.40.5-0.80.7-0.7-0.80.70.70.8-0.60.6-0.6-0.60.7-0.8
Locomotion velocity, hab. session 10.10.10.2-0.3-0.1-0.10.1-0.40.3-0.3-0.40.30.30.4-0.20.2-0.2-0.20.3-0.4
Time in familiar zone, hab. session 20.00.10.1-0.4-0.2-0.1-0.0-0.20.3-0.1-0.40.20.20.4-0.10.2-0.1-0.10.0-0.3
Time in novel zone, hab. session 20.20.20.4-0.1-0.2-0.2-0.40.6-0.50.60.6-0.5-0.5-0.50.4-0.50.40.4-0.70.4
Total zone transitions, hab. session 20.10.10.3-0.5-0.5-0.4-0.30.1-0.20.20.2-0.2-0.2-0.10.3-0.40.40.4-0.1-0.0
Total locomotion distance, hab. session 20.60.81.40.10.40.60.7-1.01.0-0.9-1.01.01.01.1-0.80.8-0.8-0.80.9-1.2
Locomotion velocity, hab. session 20.71.01.60.20.50.70.8-1.21.1-1.1-1.11.11.11.2-0.90.9-0.9-0.91.1-1.3
Novel to familiar place preference ratio0.10.10.3-0.5-0.5-0.4-0.40.1-0.20.20.2-0.2-0.2-0.10.3-0.40.30.3-0.1-0.3
Novelty place preference0.20.20.3-0.5-0.5-0.5-0.50.3-0.40.30.4-0.4-0.4-0.30.5-0.50.40.4-0.2-0.1
Time in novel zone, NPP test0.20.20.3-0.4-0.5-0.5-0.50.4-0.50.40.5-0.5-0.5-0.40.5-0.60.50.5-0.30.1
Total zone transitions, NPP test0.91.32.00.60.81.01.0-1.31.3-1.1-1.31.31.31.3-1.11.1-1.1-1.11.1-1.4
Total locomotion distance, NPP test0.60.81.9-0.00.30.60.6-1.11.0-0.9-1.01.01.01.2-0.80.8-0.9-0.90.9-1.4
Locomotion velocity, NPP test1.11.53.30.10.50.80.9-1.51.4-1.2-1.41.41.41.6-1.11.2-1.2-1.21.2-1.8
Intraocular pressure0.81.12.20.60.61.00.7-1.11.2-0.9-1.11.51.21.3-1.11.0-0.9-0.90.9-1.3
Delta distance traveled before/after self-admin1.01.11.5-0.6-0.8-0.9-1.01.2-1.11.11.1-1.2-1.1-1.11.0-1.11.10.9-1.01.1
Delta ambulatory time before/after self-admin0.20.20.50.1-0.1-0.2-0.30.6-0.50.50.6-0.7-0.5-0.60.3-0.60.40.2-0.40.7
Parametrial fat weight2.54.97.1-1.6-1.9-2.0-2.22.4-2.22.52.5-2.1-2.3-2.32.2-2.22.02.1-2.72.2
Pavlov. Cond. lever latency3.03.86.7-2.6-2.4-2.2-2.22.0-1.62.31.7-1.8-1.6-1.31.9-1.91.81.8-2.41.1
Pavlov. Cond. magazine entry latency3.14.06.82.62.52.32.2-1.91.7-2.1-1.71.91.81.5-2.02.0-2.0-2.02.1-1.1
Pavlov. Cond. change in total contacts0.30.31.71.30.90.60.6-0.2-0.1-0.50.10.1-0.0-0.3-0.20.2-0.2-0.20.70.6
Pavlov. Cond. index score3.95.08.73.02.82.62.5-2.21.9-2.5-1.82.11.91.5-2.22.2-2.2-2.22.6-1.1
Pavlov. Cond. latency score3.13.97.72.82.52.32.2-2.01.6-2.3-1.61.71.61.2-1.91.9-1.9-1.92.5-1.0
Pavlov. Cond. lever contacts2.12.45.42.32.11.81.8-1.61.1-1.9-1.11.31.10.8-1.41.4-1.4-1.42.1-0.6
Pavlov. Cond. magazine entry number3.34.15.5-2.3-2.3-2.3-2.21.9-2.02.11.9-2.0-2.0-1.72.1-2.12.12.1-1.91.1
Pavlov. Cond. intertrial magazine entries0.20.31.7-1.3-1.0-0.6-0.70.20.00.5-0.20.10.00.40.3-0.10.30.3-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.4.15.28.62.92.82.62.5-2.31.9-2.5-1.92.12.01.6-2.32.2-2.2-2.22.7-1.2
Pavlov. Cond. response bias4.15.08.02.82.72.62.5-2.22.0-2.4-2.02.22.01.7-2.32.2-2.2-2.22.4-1.1
Pavlov. Cond. lever latency0.10.10.30.0-0.1-0.3-0.20.4-0.60.30.5-0.5-0.4-0.50.4-0.30.40.4-0.20.5
Pavlov. Cond. magazine entry latency0.20.30.60.0-0.2-0.4-0.40.5-0.60.40.7-0.6-0.7-0.80.5-0.60.50.5-0.20.7
Pavlov. Cond. change in total contacts0.30.50.7-0.8-0.8-0.8-0.80.6-0.60.70.6-0.6-0.7-0.60.7-0.70.70.7-0.60.4
Pavlov. Cond. index score0.00.00.0-0.0-0.1-0.1-0.10.00.00.10.0-0.1-0.1-0.10.0-0.10.10.1-0.00.1
Pavlov. Cond. latency score0.10.10.1-0.2-0.3-0.3-0.30.3-0.20.30.3-0.3-0.3-0.30.3-0.40.30.3-0.20.4
Pavlov. Cond. lever contacts0.10.10.5-0.7-0.6-0.3-0.40.00.10.2-0.10.00.00.20.1-0.20.20.2-0.2-0.3
Pavlov. Cond. magazine entry number0.30.30.50.30.50.50.6-0.50.6-0.5-0.70.60.60.7-0.60.6-0.6-0.60.3-0.5
Pavlov. Cond. intertrial magazine entries2.63.44.62.12.12.12.1-1.71.7-1.9-1.71.81.81.6-1.92.0-1.9-1.91.7-1.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.1-0.1-0.1-0.10.1-0.00.10.0-0.1-0.1-0.10.1-0.10.10.1-0.00.2
Pavlov. Cond. response bias0.00.00.2-0.1-0.10.1-0.1-0.20.3-0.1-0.20.20.20.2-0.10.0-0.1-0.10.2-0.4
Time in closed arm before self-admin0.00.00.1-0.1-0.0-0.1-0.0-0.10.10.0-0.10.10.00.10.0-0.1-0.1-0.30.00.1
Time in closed arm after self-admin1.31.41.7-1.2-1.2-1.3-1.21.1-1.11.11.0-1.1-1.1-1.01.2-1.31.31.3-1.20.9
Time in open arm before self-admin0.70.81.51.21.11.10.9-0.80.7-0.9-0.70.40.80.7-0.90.8-0.8-0.91.0-0.9
Time in open arm after self-admin1.11.21.81.31.21.31.2-1.11.1-1.1-1.00.81.11.1-1.31.1-0.9-0.61.2-1.2
Bone: periosteal estimation1.02.05.80.70.0-0.6-0.71.6-1.81.11.8-1.5-1.7-2.11.3-1.21.31.2-1.12.4
Bone: periosteal perimeter0.20.41.61.10.60.10.10.5-0.80.10.8-0.6-0.7-1.00.4-0.30.30.3-0.11.3
Bone: post-yield work0.70.93.01.71.41.31.1-0.60.6-0.8-0.70.90.70.4-0.91.0-0.9-0.90.7-0.1
Progressive ratio test 1 active lever presses0.10.10.20.00.10.10.4-0.50.1-0.3-0.2-0.10.30.3-0.3-0.00.10.00.3-0.5
Progressive ratio test 1 breakpoint0.10.10.2-0.10.10.00.3-0.40.1-0.3-0.2-0.20.20.3-0.2-0.10.20.20.3-0.4
Progressive ratio test 1 inactive lever presses0.20.21.0-1.0-0.8-0.7-0.50.2-0.20.3-0.1-0.3-0.3-0.10.4-0.40.90.6-0.2-0.0
Progressive ratio test 2 active lever presses0.30.31.2-0.00.20.40.5-0.80.6-0.6-0.60.80.70.7-0.50.2-0.2-0.40.8-1.1
Progressive ratio test 2 breakpoint0.60.61.90.00.30.50.6-1.10.8-0.8-0.81.10.91.0-0.70.4-0.4-0.60.9-1.4
Progressive ratio test 2 inactive lever presses0.20.30.8-0.0-0.2-0.3-0.30.3-0.50.50.5-0.6-0.5-0.50.6-0.80.90.8-0.30.4
Incentive Sensitization - Responses0.40.41.00.20.30.50.5-0.80.7-0.7-0.61.00.70.8-0.60.4-0.7-0.40.8-1.0
Incentive Sensitization - Breakpoint0.60.61.30.30.50.70.6-0.90.8-0.8-0.81.20.90.9-0.70.6-0.8-0.50.9-1.1
Sum of active levers in priming session hrs 5-60.30.30.50.10.30.30.6-0.70.6-0.6-0.70.40.60.6-0.40.7-0.6-0.50.7-0.7
Progressive ratio5.26.07.8-1.7-2.1-2.2-2.32.6-2.72.62.8-2.5-2.6-2.62.6-2.42.42.6-2.52.4
Food seeking constrained by brief footshock0.00.00.10.10.10.10.1-0.10.1-0.10.0-0.00.10.1-0.1-0.30.00.20.1-0.2
Seeking ratio, punishment vs. effort4.45.36.81.51.92.02.2-2.52.6-2.5-2.62.22.42.5-2.52.1-2.4-2.42.3-2.3
Retroperitoneal fat weight0.51.51.9-0.8-1.0-1.1-1.21.3-1.31.31.3-1.3-1.2-1.21.1-1.31.21.4-1.41.2
Reaction time number correct0.60.92.6-1.6-1.4-1.3-1.20.8-0.60.90.7-0.8-0.7-0.50.8-0.90.70.7-1.00.4
Reaction time mean minus median2.33.010.03.22.62.62.0-1.31.1-1.6-1.01.31.30.9-1.51.7-1.5-1.51.7-0.7
Reaction time mean minus median AUC2.02.57.12.72.32.21.8-1.31.2-1.6-1.01.21.31.0-1.41.6-1.5-1.51.6-0.7
Reaction time num false alarms0.20.20.6-0.1-0.2-0.4-0.40.6-0.60.40.6-0.4-0.6-0.70.4-0.30.10.2-0.40.8
Reaction time num false alarms AUC0.30.51.1-0.2-0.3-0.6-0.50.8-0.90.60.8-0.8-0.9-1.00.6-0.50.40.5-0.61.1
Reaction time trials correct on left0.60.92.6-1.6-1.4-1.3-1.20.8-0.60.90.7-0.8-0.7-0.50.8-0.90.70.7-1.00.4
Reaction time trials on left0.60.82.3-1.5-1.3-1.2-1.10.8-0.60.90.7-0.8-0.7-0.60.8-0.90.70.7-1.00.4
Reaction time mean2.83.99.23.02.72.62.2-1.71.4-2.0-1.41.61.71.3-1.82.1-1.8-1.92.1-1.1
Reaction time mean AUC2.93.99.43.12.72.62.2-1.71.4-2.0-1.41.61.71.3-1.82.1-1.8-1.92.0-1.1
Median of all reaction times2.02.75.62.42.12.11.8-1.51.3-1.7-1.21.51.41.1-1.51.8-1.5-1.61.8-1.0
Reaction time omissions1.82.56.52.62.22.11.8-1.31.1-1.6-1.11.41.30.9-1.51.6-1.3-1.31.7-0.7
Reaction time false alarm rate0.10.10.60.80.60.20.30.2-0.3-0.10.3-0.3-0.3-0.50.00.2-0.1-0.00.10.7
Reaction time premature initiation rate1.52.02.7-1.0-1.2-1.4-1.31.4-1.51.41.6-1.4-1.5-1.51.6-1.51.51.4-1.31.6
Reaction time premature initiations2.63.74.6-1.9-1.9-2.1-1.91.9-1.91.92.0-1.8-2.0-1.92.1-2.01.91.8-1.91.8
Std. dev. reaction times2.02.910.03.22.62.52.0-1.31.0-1.6-0.91.11.30.8-1.51.7-1.5-1.51.7-0.5
Reaction time trials completed0.60.82.3-1.5-1.3-1.2-1.10.8-0.60.90.7-0.8-0.7-0.60.8-0.90.70.7-1.00.4
Reaction time trials AUC0.50.72.3-1.5-1.3-1.2-1.10.8-0.50.80.6-0.7-0.7-0.50.8-0.80.60.6-1.00.3
Run reversals in cocaine runway, females0.60.61.5-1.2-1.1-1.0-1.00.6-0.50.70.2-0.5-0.6-0.40.8-0.80.80.9-0.6-0.0
Run reversals in cocaine runway, males0.30.32.61.61.11.00.60.0-0.1-0.10.4-0.2-0.0-0.3-0.3-0.0-0.2-0.10.20.5
Latency to leave start box in cocaine runway0.10.10.3-0.2-0.2-0.4-0.10.1-0.20.20.5-0.6-0.3-0.30.2-0.20.30.4-0.20.5
Latency to leave start box in cocaine runway, F0.20.30.40.40.60.40.7-0.70.6-0.6-0.40.30.50.5-0.70.5-0.4-0.40.6-0.4
Latency to leave start box in cocaine runway, M2.12.02.5-1.3-1.4-1.5-1.41.4-1.31.41.5-1.5-1.4-1.41.6-1.11.01.4-1.51.4
Std. dev. time between licks in bursts1.11.44.72.21.91.41.5-0.90.7-1.2-0.70.60.70.3-1.11.1-1.0-1.21.2-0.0
Total sessions with >9 infusions0.10.10.4-0.2-0.2-0.3-0.00.0-0.40.20.0-0.4-0.2-0.20.3-0.50.60.4-0.00.2
Short access day 1 total inactive lever presses0.40.41.91.41.20.90.9-0.40.2-0.6-0.30.20.30.0-0.40.5-0.4-0.50.70.2
Short access day 10 total inactive lever presses0.10.20.50.70.60.50.4-0.10.3-0.3-0.40.20.30.1-0.30.7-0.4-0.20.30.1
Short access day 1 total infusions0.20.30.50.40.50.40.7-0.70.5-0.7-0.60.20.50.5-0.50.2-0.3-0.50.6-0.4
Short access day 10 total infusions0.10.10.6-0.3-0.3-0.4-0.30.2-0.40.20.1-0.4-0.4-0.30.4-0.70.80.4-0.20.1
Short access total infusions0.10.10.5-0.3-0.2-0.4-0.10.1-0.30.20.2-0.6-0.3-0.30.4-0.70.70.3-0.10.3
Short access day 1 locomotion3.33.54.61.21.51.71.9-2.12.0-2.1-2.12.02.02.0-1.91.8-1.6-1.92.0-1.9
Short access day 10 total locomotion0.30.41.51.21.10.70.8-0.40.4-0.8-0.20.30.30.0-0.50.4-0.5-0.60.50.3
Short access total locomotion0.30.30.60.70.70.60.8-0.70.5-0.7-0.60.30.50.4-0.50.4-0.3-0.50.6-0.3
One hour access (0.3 mA shock)0.50.61.20.60.70.80.8-1.00.8-0.8-0.80.60.90.9-0.80.5-0.4-0.51.0-1.1
Compulsive drug intake3.33.44.31.31.61.61.9-2.12.0-1.9-1.91.81.91.9-1.91.8-2.0-1.81.8-1.8
One hour access (shock baseline)0.30.40.80.0-0.3-0.2-0.50.6-0.70.70.8-0.7-0.6-0.70.6-0.90.90.8-0.50.5
Social response proportion0.10.10.50.70.60.40.5-0.0-0.0-0.20.1-0.30.1-0.1-0.20.1-0.10.00.00.5
Social responses0.20.20.8-0.1-0.1-0.3-0.10.5-0.40.20.5-0.7-0.4-0.50.3-0.40.30.4-0.60.9
Social time1.01.35.32.31.91.61.5-0.80.5-1.0-0.40.50.70.3-1.10.9-1.0-0.91.00.2
Soleus weight0.61.88.83.02.51.71.8-0.60.3-1.1-0.40.50.5-0.1-1.11.1-1.1-1.11.10.7
Bone: stiffness1.72.63.1-1.5-1.7-1.7-1.71.6-1.71.61.6-1.5-1.7-1.61.7-1.71.71.7-1.51.4
Tibialis anterior weight0.20.72.3-1.5-1.3-1.2-1.00.6-0.50.80.5-0.4-0.6-0.40.7-0.80.70.7-0.80.2
Time to tail flick, vehicle, before self-admin0.30.30.60.80.70.70.6-0.50.3-0.4-0.50.70.50.4-0.50.4-0.7-0.70.5-0.3
Time to tail flick, vehicle, after self-admin1.81.92.91.71.61.61.5-1.21.3-1.3-1.31.51.31.1-1.41.4-1.4-1.31.4-1.0
Time to tail flick, test, before self-admin0.20.20.5-0.6-0.6-0.5-0.50.4-0.30.50.3-0.3-0.4-0.30.2-0.60.60.7-0.40.2
Time to tail flick, test, after self-admin2.02.13.11.61.41.81.3-1.41.2-1.4-1.31.61.41.3-1.41.6-1.3-1.51.5-1.5
Delta time to tail flick, vehicle, before/after SA0.70.71.00.60.70.80.8-0.91.0-0.8-0.81.00.90.9-0.80.9-0.8-0.90.8-1.0
Delta time to tail flick, test, before/after SA1.41.32.00.80.81.10.9-1.21.0-1.1-1.01.31.11.1-1.01.4-1.3-1.41.1-1.3
Tibia length0.92.48.30.90.2-0.5-0.61.8-1.91.31.9-1.7-1.8-2.31.3-1.31.21.2-1.42.9
Ambulatory time before self-admin0.00.00.10.30.20.20.1-0.00.1-0.1-0.3-0.10.10.0-0.10.2-0.10.10.1-0.1
Ambulatory time after self-admin0.10.10.40.70.40.40.10.20.00.10.10.0-0.0-0.1-0.10.2-0.2-0.30.00.3
Bone: tissue strength4.64.45.5-1.6-1.9-2.1-2.22.1-2.32.02.3-2.2-2.3-2.32.2-2.32.22.2-1.71.6
Total heroin consumption0.00.10.30.20.10.20.1-0.20.2-0.2-0.2-0.00.20.2-0.20.2-0.5-0.10.2-0.4
Bone: trabecular number0.61.04.2-0.4-0.00.50.4-1.21.1-0.8-1.11.31.11.4-0.80.8-0.7-0.61.0-2.0
Bone: trabecular spacing2.43.16.5-0.4-0.8-1.3-1.31.9-2.01.52.0-2.1-2.0-2.31.7-1.81.71.6-1.62.5
Bone: trabecular thickness0.60.72.1-0.10.20.50.4-1.00.9-0.7-0.91.00.91.1-0.70.7-0.7-0.70.9-1.4
Bone: trabecular tissue density1.82.63.4-1.1-1.3-1.6-1.51.6-1.81.51.8-1.8-1.8-1.81.7-1.71.71.6-1.41.7
Water consumed over 24 hours0.00.10.20.40.40.30.3-0.10.1-0.2-0.20.10.10.1-0.30.2-0.2-0.10.2-0.0
Number of responses in last shaping day0.10.10.40.10.1-0.30.10.1-0.50.10.2-0.4-0.4-0.50.2-0.50.60.4-0.10.5