Hub : Genes

Mcat

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_006242091.1 0.03 0.02 2.1e-05 0.04 0.04 0.03 0.03 2.4e-05 4.6e-05 4.4e-04 1.3e-04
2 NAcc isoform ratio NM_001191788.1 0.06 0.04 1.1e-06 0.05 0.05 0.05 0.05 7.3e-07 2.6e-06 4.3e-06 8.0e-07
3 NAcc alternative TSS NM_001191788.1 0.09 0.05 1.7e-15 0.12 0.12 0.13 0.12 9.7e-14 4.5e-14 1.1e-14 2.8e-14
4 Brain isoform ratio NM_001191788.1 0.35 0.16 0.0e+00 0.44 0.44 0.45 0.46 3.9e-44 1.8e-44 1.4e-45 5.2e-47
5 PL isoform ratio NM_001191788.1 0.08 0.05 1.5e-12 0.1 0.1 0.09 0.1 9.1e-11 1.3e-10 1.8e-10 6.8e-11
6 PL alternative TSS NM_001191788.1 0.21 0.1 0.0e+00 0.25 0.24 0.25 0.26 3.6e-27 2.1e-26 4.9e-27 5.9e-28
7 NAcc alternative TSS XM_006242091.1 0.09 0.05 4.4e-16 0.12 0.13 0.13 0.13 2.6e-14 1.1e-14 1.8e-14 4.4e-15
8 Adipose gene expression Mcat 0.06 0.07 3.2e-04 0.03 0.02 0.03 0.03 2.5e-04 1.4e-03 4.1e-04 4.3e-04
9 PL alternative TSS XM_006242091.1 0.2 0.1 0.0e+00 0.26 0.24 0.24 0.25 4.4e-28 4.4e-26 4.3e-26 1.3e-27
10 pVTA isoform ratio NM_001191788.1 0.16 0.1 3.6e-07 0.2 0.15 0.14 0.17 7.3e-09 4.4e-07 1.8e-06 1.0e-07
11 Eye alternative TSS NM_001191788.1 0.28 0.18 2.7e-03 0.09 -0.01 -0.01 0.01 1.5e-02 4.6e-01 5.4e-01 2.1e-01
12 Eye alternative TSS XM_006242091.1 0.3 0.18 1.4e-03 0.12 -0.01 -0 0.02 7.8e-03 5.0e-01 3.6e-01 1.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.40.6-0.70.80.6-0.7-0.6-0.60.6-0.6-0.60.70.7-0.7
Area under the delay curve2.02.12.9-1.71.51.5-1.3-1.3-1.41.5-1.4-1.41.51.4-1.4
BMI with tail1.85.97.02.3-2.5-2.52.32.72.4-2.52.42.5-2.3-2.42.4
BMI without tail0.71.41.81.1-1.4-1.21.01.31.2-1.31.21.3-1.1-1.11.1
Body weight1.66.88.42.1-2.9-2.72.72.82.8-2.82.82.9-2.1-2.22.2
Weight adjusted by age0.10.20.30.5-0.3-0.40.30.30.4-0.40.30.3-0.4-0.60.6
Bone surface0.00.00.1-0.10.0-0.20.30.00.2-0.00.10.00.10.1-0.1
Bone volume0.00.00.0-0.10.1-0.10.1-0.00.10.10.0-0.10.20.2-0.2
Breakpoint value in progressive ratio session0.10.10.20.1-0.4-0.30.30.10.4-0.30.40.4-0.1-0.10.1
Number of licking bursts0.10.20.2-0.40.40.4-0.4-0.4-0.40.4-0.3-0.40.40.4-0.4
Context. condit. distance diff. score5.66.88.12.7-2.5-2.42.52.82.5-2.52.52.5-2.8-2.72.7
Locomotion velocity, session 10.70.81.11.0-0.8-1.11.10.81.0-0.80.80.8-0.8-0.80.8
Locomotion distance, session 10.30.40.8-0.20.80.6-0.9-0.7-0.70.7-0.7-0.70.60.6-0.6
Locomotion velocity, session 21.21.42.11.3-0.9-1.51.21.11.1-1.21.11.1-1.2-1.21.2
Locomotion distance, session 21.11.52.2-0.81.51.1-1.4-1.3-1.31.2-1.2-1.21.31.2-1.2
Locomotion velocity, session 30.80.91.31.1-0.6-1.10.81.00.8-1.00.90.9-1.1-1.01.0
Locomotion distance, session 30.80.91.5-0.61.21.0-1.2-0.7-1.10.9-0.9-0.90.70.7-0.7
Stereotopy head waving bouts, day 31.11.31.90.9-1.1-1.41.31.11.2-1.11.11.0-1.1-1.21.2
Stereotopy head waving duration, day 35.76.88.12.4-2.6-2.92.72.52.7-2.62.62.5-2.5-2.62.6
Locomotion velocity, session 70.10.10.30.40.1-0.30.00.50.1-0.20.20.2-0.3-0.50.5
Locomotion distance, session 70.81.01.7-0.81.30.9-1.2-0.7-1.21.0-1.0-1.01.00.8-0.8
Stereotopy head waving bouts, day 75.36.07.22.6-2.4-2.52.72.42.6-2.32.52.4-2.4-2.32.3
Stereotopy head waving duration, day 73.44.24.92.1-2.1-2.12.21.92.2-2.02.12.0-2.0-1.91.9
Locomotion velocity, session 86.88.19.23.0-2.7-2.72.72.93.0-2.82.92.9-2.8-2.82.8
Locomotion distance, session 81.01.42.31.5-1.0-1.11.11.31.2-1.11.11.1-1.2-1.21.2
Degree of sensitization distance0.80.81.10.8-0.9-1.01.00.91.0-0.90.90.9-0.8-0.90.9
Degree of sensitization stereotypy3.74.15.02.2-2.0-2.02.12.02.1-2.02.12.1-2.0-1.91.9
Conditioned locomotion0.00.00.1-0.0-0.4-0.10.30.10.3-0.10.10.2-0.1-0.10.1
Cocaine response after cond. corrected0.00.00.10.30.10.10.1-0.2-0.00.1-0.1-0.10.00.0-0.0
Cocaine response after cond. not corrected0.00.00.10.40.10.00.1-0.0-0.00.0-0.1-0.1-0.1-0.10.1
Cocaine response before conditioning0.10.10.1-0.30.30.3-0.3-0.1-0.30.3-0.3-0.30.20.2-0.2
Saline control response0.20.30.40.3-0.7-0.50.60.50.6-0.50.50.4-0.4-0.40.4
Bone: connectivity density0.10.10.3-0.50.40.1-0.3-0.2-0.20.2-0.2-0.20.30.3-0.3
Bone: cortical apparent density1.41.92.2-1.51.31.4-1.1-1.4-1.41.4-1.4-1.41.41.4-1.4
Bone: cortical area1.42.22.91.5-1.6-1.51.71.41.6-1.41.51.5-1.3-1.31.3
Bone: cortical porosity0.70.81.00.6-0.7-0.90.81.00.8-0.90.80.9-1.0-1.01.0
Bone: cortical porosity1.31.41.61.0-1.0-1.31.31.31.2-1.21.01.2-1.3-1.31.3
Bone: cortical thickness0.00.10.1-0.3-0.40.10.30.10.4-0.10.40.30.00.0-0.0
Bone: cortical thickness0.20.20.40.4-0.6-0.30.30.50.5-0.50.50.4-0.5-0.50.5
Bone: cortical tissue density1.31.72.0-1.41.31.3-1.1-1.4-1.31.4-1.3-1.31.31.3-1.3
Condit. Reinf. active minus inactive responses1.61.82.5-1.31.31.2-0.9-1.5-1.31.4-1.3-1.31.61.5-1.5
Condit. Reinf. active-inactive response ratio0.00.00.2-0.1-0.1-0.20.4-0.00.1-0.10.00.00.0-0.00.0
Condit. Reinf. active responses4.15.15.9-2.12.22.2-1.9-2.4-2.22.2-2.2-2.22.42.4-2.4
Condit. Reinf. inactive responses4.14.95.5-2.02.22.2-2.3-2.2-2.22.1-2.2-2.12.22.3-2.3
Incentive salience index mean2.63.24.0-1.81.71.7-1.4-2.0-1.71.8-1.7-1.82.01.9-1.9
Condit. Reinf. lever presses2.63.54.3-1.91.81.7-1.5-2.1-1.91.9-1.9-1.92.01.9-1.9
Condit. Reinf. active minus inactive responses0.00.10.20.0-0.3-0.20.40.10.4-0.20.20.3-0.1-0.10.1
Condit. Reinf. active-inactive response ratio0.10.10.30.1-0.4-0.30.60.10.5-0.10.20.20.00.0-0.0
Condit. Reinf. active responses0.71.01.60.8-1.0-1.01.30.91.2-0.90.90.9-0.9-0.90.9
Condit. Reinf. inactive responses0.91.21.60.9-0.9-1.11.11.21.1-1.00.90.9-1.2-1.21.2
Condit. Reinf. lever presses0.10.20.4-0.30.50.3-0.1-0.4-0.40.5-0.6-0.60.30.3-0.3
Condit. Reinf. lever reinforcers received0.10.20.70.2-0.4-0.50.80.30.6-0.30.30.3-0.4-0.40.4
Conditioned reinforcement - actives0.30.30.5-0.50.60.6-0.0-0.6-0.50.6-0.4-0.50.60.7-0.7
Conditioned reinforcement - inactives0.10.10.2-0.00.20.2-0.2-0.3-0.20.2-0.1-0.10.30.4-0.4
Conditioned locomotion0.50.61.00.9-0.8-0.71.00.70.8-0.70.90.8-0.9-0.60.6
Patch foraging indifference point 0 sec0.10.10.3-0.30.30.2-0.2-0.3-0.30.2-0.3-0.30.40.6-0.6
Patch foraging indifference point AUC0.10.20.3-0.50.50.3-0.3-0.4-0.40.3-0.4-0.40.40.4-0.4
Delay disc. indifference point, 0s delay0.40.40.80.5-0.4-0.70.60.90.6-0.70.60.7-0.6-0.70.7
Delay disc. indifference point, 16s delay4.14.24.9-2.22.12.1-1.8-2.1-2.02.1-2.0-2.02.12.1-2.1
Delay disc. indifference point, 2s delay0.30.40.5-0.60.70.7-0.7-0.4-0.70.7-0.5-0.60.70.5-0.5
Delay disc. indifference point, 24s delay0.60.61.2-1.10.70.8-0.6-0.7-0.70.8-0.7-0.70.90.8-0.8
Delay disc. indifference point, 4s delay0.10.10.2-0.20.40.4-0.3-0.3-0.40.4-0.5-0.40.40.3-0.3
Delay disc. indifference point, 8s delay3.23.34.0-2.01.81.9-1.7-1.7-1.81.9-1.8-1.71.81.8-1.8
Indifference point function ln k1.62.22.71.1-1.6-1.41.41.61.5-1.41.61.6-1.4-1.41.4
Indifference point function log k1.62.22.71.1-1.6-1.41.41.61.5-1.41.61.6-1.4-1.41.4
Patch foraging total patch changes 0 sec0.10.20.3-0.30.40.2-0.3-0.4-0.40.3-0.3-0.30.50.6-0.6
Patch foraging total patch changes 12 sec0.00.00.20.3-0.1-0.50.40.10.1-0.20.10.0-0.1-0.00.0
Patch foraging total patch changes 18 sec0.00.00.2-0.50.10.00.1-0.00.00.1-0.1-0.00.40.2-0.2
Patch foraging total patch changes 24 sec0.10.10.3-0.40.60.2-0.4-0.3-0.40.3-0.4-0.40.40.3-0.3
Patch foraging total patch changes 6 sec0.00.00.00.10.0-0.00.20.10.1-0.10.10.10.00.1-0.1
Patch foraging time to switch 0 sec0.40.60.8-0.60.90.6-0.6-0.8-0.70.8-0.9-0.90.90.7-0.7
Patch foraging water rate 0 sec0.71.11.61.3-0.9-1.00.71.10.9-1.21.01.1-1.3-1.01.0
Patch foraging water rate 12 sec0.61.01.71.1-0.9-0.90.31.10.7-0.91.00.9-1.3-1.21.2
Patch foraging water rate 18 sec0.10.10.10.20.20.3-0.1-0.3-0.30.4-0.2-0.30.10.4-0.4
Patch foraging water rate 24 sec2.02.83.71.3-1.9-1.71.71.61.7-1.61.81.7-1.7-1.61.6
Patch foraging water rate 6 sec0.10.10.2-0.30.40.2-0.4-0.2-0.50.3-0.3-0.30.30.4-0.4
Seeking ratio, delayed vs. immediate footshock2.12.43.7-1.41.71.4-1.9-1.6-1.51.5-1.5-1.51.41.6-1.6
Distance traveled before self-admin0.20.20.4-0.10.40.2-0.40.1-0.40.3-0.4-0.4-0.6-0.70.7
Distance traveled after self-admin0.40.41.00.5-0.5-0.60.50.70.4-0.50.50.4-1.0-1.01.0
Extensor digitorum longus weight0.00.10.10.3-0.1-0.1-0.10.2-0.0-0.20.20.3-0.3-0.30.3
Bone: elastic displacement1.41.61.81.3-1.2-1.31.21.31.3-1.31.31.3-1.3-1.31.3
Bone: elastic work4.55.86.82.6-2.4-2.52.42.42.4-2.42.42.3-2.4-2.42.4
Bone: endosteal estimation2.24.98.42.9-1.8-2.52.22.22.0-2.11.91.9-2.3-2.32.3
Bone: endosteal perimeter2.04.16.02.5-1.9-2.22.22.02.0-1.91.81.8-1.9-1.91.9
Epididymis fat weight1.33.14.21.2-1.9-1.82.01.91.8-1.71.71.8-1.5-1.71.7
Delta time in closed arm before/after self-admin0.00.00.10.00.1-0.20.3-0.3-0.0-0.2-0.0-0.00.10.1-0.1
Delta time in open arm before/after self-admin0.30.30.60.8-0.1-0.30.00.70.1-0.30.10.2-0.8-0.80.8
Diff in mean of infusions in LGA sessions1.41.52.2-1.01.31.0-1.1-1.5-1.21.0-1.3-1.11.31.4-1.4
Delay discount exponential model param1.92.02.71.6-1.4-1.51.31.31.4-1.51.41.3-1.5-1.41.4
Extinction: sum of active levers before priming0.30.30.7-0.20.80.5-0.2-0.3-0.60.6-0.7-0.70.40.4-0.4
Active lever presses in extinction session 60.50.50.70.8-0.8-0.70.60.70.7-0.70.70.7-0.7-0.70.7
Bone: final force0.71.21.81.4-1.1-1.21.31.01.1-1.11.01.0-0.9-0.90.9
Bone: final moment1.32.13.01.7-1.5-1.51.61.41.4-1.41.41.3-1.3-1.31.3
Food consumed during 24 hour testing period2.53.13.61.9-1.9-1.71.81.71.6-1.71.71.6-1.8-1.81.8
Glucose0.40.71.2-1.11.00.8-0.9-0.8-0.80.7-0.7-0.60.70.8-0.8
Heart weight2.33.34.21.5-2.1-1.61.92.01.8-1.81.71.8-1.8-1.91.9
Delay discount hyperbolic model param1.31.41.81.3-1.2-1.31.11.11.2-1.31.21.1-1.3-1.11.1
Intermittent access intake day 1-15 change0.70.71.0-0.90.90.9-0.6-0.7-0.90.9-0.9-0.90.71.0-1.0
Intermittent access intake escalation0.50.50.6-0.70.70.7-0.5-0.4-0.80.7-0.8-0.80.50.7-0.7
Intermittent access intake escalation 20.10.10.2-0.30.40.4-0.2-0.1-0.40.4-0.4-0.40.20.4-0.4
Intermitt. access day 1 inactive lever presses0.80.91.41.2-0.8-0.91.00.90.9-0.90.90.9-0.9-1.01.0
Intermitt. access day 15 inactive lever presses0.40.51.01.0-0.8-0.70.90.60.7-0.60.60.5-0.6-0.50.5
Intermitt. access escalation Index0.10.10.2-0.20.30.4-0.3-0.5-0.40.5-0.3-0.50.30.3-0.3
Intermittent access day 1 total infusions0.60.71.00.7-0.8-0.80.90.90.9-0.80.91.0-0.5-0.60.6
Intermittent access day 15 total infusions0.00.00.20.3-0.1-0.20.20.40.1-0.20.10.2-0.2-0.10.1
Intermittent access terminal intake (last 3 days)0.00.00.10.30.3-0.10.00.2-0.1-0.1-0.00.1-0.10.1-0.1
Intermittent access total infusions0.10.20.40.7-0.2-0.40.30.50.3-0.40.30.4-0.4-0.30.3
Intermittent access day 1 locomotion0.00.00.10.1-0.2-0.10.20.10.2-0.10.30.30.30.1-0.1
Intermittent access day 15 total locomotion0.10.10.20.4-0.3-0.20.10.30.2-0.30.20.3-0.4-0.20.2
Intermittent access total locomotion0.20.20.30.6-0.4-0.50.30.60.4-0.50.40.5-0.5-0.40.4
Intermittent access standard deviation0.30.30.70.9-0.5-0.60.70.80.6-0.60.60.6-0.4-0.30.3
Left kidney weight13.638.247.06.2-6.5-6.56.96.06.4-6.26.16.1-5.9-5.75.7
Right kidney weight15.042.247.16.7-6.8-6.76.96.26.6-6.66.66.4-6.3-6.06.0
Cocaine induced anxiety2.22.63.61.9-1.7-1.81.41.41.5-1.71.61.4-1.7-1.61.6
Post-drug Anxiety2.02.22.71.5-1.6-1.61.31.41.5-1.61.61.5-1.4-1.31.3
Baseline Anxiety1.51.63.3-1.81.21.4-1.1-1.1-1.01.2-1.0-0.81.51.3-1.3
Tail length0.00.10.3-0.5-0.20.2-0.0-0.20.00.10.00.00.40.4-0.4
Length with tail0.20.81.70.3-1.0-1.01.30.81.1-1.01.21.1-0.4-0.40.4
Length without tail0.40.91.70.6-0.8-1.21.30.91.1-1.01.11.1-0.6-0.60.6
Times rat made contact with spout1.92.22.71.4-1.6-1.51.21.41.4-1.61.61.5-1.5-1.51.5
Lifetime Intake0.50.50.90.9-0.6-0.70.70.80.6-0.70.60.6-0.8-0.80.8
Liver weight, left0.10.20.50.4-0.7-0.60.70.40.6-0.40.40.4-0.3-0.20.2
Liver weight, right0.20.31.10.2-0.7-0.71.10.50.8-0.50.60.6-0.2-0.20.2
Locomotor activity2.33.65.12.0-1.9-1.92.31.62.1-1.92.02.0-1.8-1.61.6
Locomotor testing distance0.00.10.20.30.20.2-0.1-0.4-0.10.3-0.2-0.20.10.3-0.3
Locomotor testing rearing0.30.50.80.9-0.7-0.60.90.50.7-0.50.50.6-0.8-0.70.7
Locomotion in novel chamber0.10.10.4-0.60.60.4-0.30.0-0.40.3-0.2-0.20.10.1-0.1
Locomotion in novel chamber post-restriction1.01.21.6-1.01.10.9-1.3-1.0-1.11.0-1.1-1.11.01.1-1.1
Fecal boli incidents, locomotor time 10.30.30.5-0.70.60.5-0.5-0.6-0.60.6-0.7-0.70.30.5-0.5
Change in fecal boli incidents, locomotor task0.70.60.80.7-0.9-0.80.80.80.8-0.80.90.9-0.6-0.70.7
Time >=10cm from walls, locomotor time 10.00.00.10.30.3-0.1-0.0-0.2-0.0-0.0-0.1-0.00.10.1-0.1
Bouts of movement, locomotor time 10.10.10.3-0.30.30.4-0.4-0.3-0.40.4-0.6-0.40.20.3-0.3
Total resting periods, locomotor time 10.30.40.6-0.60.60.6-0.7-0.5-0.60.6-0.8-0.70.40.6-0.6
Rest time, locomotor task time 10.00.00.10.00.20.1-0.30.1-0.20.1-0.4-0.2-0.2-0.20.2
Distance moved, locomotor task time 10.10.10.40.4-0.4-0.20.6-0.10.4-0.10.60.30.1-0.10.1
Vertical activity count, locomotor time 10.00.00.10.2-0.2-0.20.3-0.20.2-0.10.30.20.10.2-0.2
Time >=10cm from walls, locomotor time 20.30.30.5-0.60.70.5-0.6-0.7-0.60.5-0.6-0.50.50.6-0.6
Bouts of movement, locomotor time 20.20.20.3-0.50.40.5-0.3-0.3-0.40.4-0.5-0.40.50.4-0.4
Total resting periods, locomotor time 20.10.20.3-0.50.30.5-0.3-0.2-0.30.4-0.4-0.30.50.4-0.4
Rest time, locomotor task time 20.10.10.3-0.50.30.4-0.4-0.1-0.30.3-0.4-0.30.20.2-0.2
Distance moved, locomotor task time 20.60.71.31.1-0.8-0.80.80.60.8-0.90.90.8-0.8-0.90.9
Vertical activity count, locomotor time 20.60.70.91.0-0.8-0.90.90.60.8-0.90.90.8-0.7-0.70.7
Light reinforcement 10.30.50.90.7-0.9-0.90.80.70.8-0.60.50.6-0.5-0.50.5
Light reinforcement 20.50.71.30.7-1.2-1.10.70.71.0-0.80.80.8-0.7-0.60.6
Bone: marrow area2.55.49.13.0-1.9-2.62.32.32.1-2.32.02.0-2.4-2.42.4
Bone: maximum diameter5.710.411.83.4-3.3-3.33.43.33.3-3.23.23.2-3.1-3.13.1
Bone: maximum force2.54.45.62.4-2.1-2.22.22.12.1-2.12.12.0-2.0-2.02.0
Bone: maximum moment3.45.87.32.7-2.4-2.52.52.42.4-2.42.42.3-2.3-2.32.3
Mean time between licks in bursts0.91.31.7-1.01.21.1-1.3-1.2-1.21.1-1.3-1.31.01.0-1.0
Mean num. licks in bursts2.12.52.81.6-1.7-1.61.41.61.5-1.61.51.6-1.6-1.61.6
Cd content in liver1.71.92.41.5-1.4-1.21.11.51.4-1.51.41.4-1.3-1.31.3
Co content in liver0.60.80.90.9-0.9-0.70.61.00.9-1.00.90.9-0.9-0.90.9
Cu content in liver6.17.48.6-2.92.82.7-2.4-2.6-2.62.8-2.8-2.82.82.8-2.8
Fe content in liver0.40.40.70.6-0.6-0.80.80.60.6-0.60.70.7-0.6-0.60.6
K content in liver0.30.30.5-0.70.50.3-0.2-0.7-0.50.6-0.6-0.60.60.6-0.6
Mg content in liver0.80.81.1-1.10.90.6-0.5-0.9-0.70.9-0.8-0.81.01.0-1.0
Mn content in liver0.00.00.10.1-0.2-0.30.20.00.3-0.20.10.1-0.1-0.10.1
Na content in liver1.71.82.4-1.41.51.4-1.5-1.3-1.41.4-1.2-1.21.31.3-1.3
Rb content in liver0.00.00.2-0.2-0.1-0.30.40.20.2-0.10.10.1-0.1-0.10.1
Se content in liver1.31.62.1-1.21.21.1-0.9-1.4-1.11.3-1.3-1.31.41.4-1.4
Sr content in liver0.90.81.4-0.90.71.1-1.2-0.9-1.00.8-0.9-0.90.80.8-0.8
Zn content in liver0.80.91.1-1.00.81.0-0.9-0.9-0.91.0-1.0-1.00.90.9-0.9
Bone: minimum diameter0.51.01.71.2-1.1-1.01.30.91.0-0.80.80.8-1.0-1.01.0
Time in familiar zone, hab. session 10.20.20.40.6-0.4-0.50.30.40.3-0.40.30.3-0.4-0.40.4
Time in novel zone, hab. session 11.01.01.20.8-1.0-0.91.01.01.1-1.11.01.0-1.0-1.01.0
Total zone transitions, hab. session 12.02.83.2-1.61.61.6-1.7-1.8-1.71.7-1.6-1.71.71.7-1.7
Total locomotion distance, hab. session 10.40.50.7-0.70.60.6-0.6-0.8-0.70.8-0.8-0.80.80.8-0.8
Locomotion velocity, hab. session 10.60.91.1-0.80.90.8-0.8-1.0-0.91.0-0.9-0.91.00.9-0.9
Time in familiar zone, hab. session 20.20.20.3-0.50.30.4-0.3-0.5-0.30.4-0.4-0.40.50.5-0.5
Time in novel zone, hab. session 21.21.21.50.9-0.9-0.91.01.20.9-1.01.11.1-1.2-1.21.2
Total zone transitions, hab. session 20.00.10.10.00.30.1-0.2-0.3-0.20.2-0.2-0.20.20.2-0.2
Total locomotion distance, hab. session 20.10.10.2-0.20.40.3-0.4-0.4-0.40.4-0.4-0.40.40.4-0.4
Locomotion velocity, hab. session 20.40.50.6-0.50.70.6-0.7-0.7-0.70.8-0.7-0.70.70.7-0.7
Novel to familiar place preference ratio3.23.33.91.6-2.0-1.51.92.01.9-1.71.81.8-1.8-1.91.9
Novelty place preference4.14.25.01.8-2.2-1.82.12.22.1-2.02.02.1-2.0-2.12.1
Time in novel zone, NPP test5.65.76.62.2-2.5-2.12.42.62.5-2.42.42.4-2.4-2.42.4
Total zone transitions, NPP test0.71.01.2-0.61.00.9-1.1-1.1-1.11.0-1.0-1.11.01.0-1.0
Total locomotion distance, NPP test0.30.40.5-0.30.60.5-0.6-0.6-0.70.6-0.6-0.70.60.6-0.6
Locomotion velocity, NPP test1.31.82.1-1.01.41.3-1.3-1.4-1.41.4-1.4-1.41.41.3-1.3
Intraocular pressure0.40.50.70.8-0.7-0.70.60.80.7-0.80.70.8-0.7-0.70.7
Delta distance traveled before/after self-admin2.02.22.81.4-1.6-1.61.61.41.6-1.61.71.6-1.3-1.21.2
Delta ambulatory time before/after self-admin3.23.54.51.6-2.1-2.02.01.82.0-2.02.12.0-1.6-1.51.5
Parametrial fat weight0.10.10.5-0.70.30.4-0.3-0.2-0.20.2-0.3-0.10.30.5-0.5
Pavlov. Cond. lever latency3.14.04.52.1-1.9-1.91.62.11.9-2.12.02.1-2.1-2.12.1
Pavlov. Cond. magazine entry latency2.43.13.7-1.91.81.8-1.7-1.9-1.71.7-1.6-1.61.81.8-1.8
Pavlov. Cond. change in total contacts2.72.83.6-1.91.71.8-1.5-1.8-1.61.7-1.6-1.61.71.7-1.7
Pavlov. Cond. index score1.92.43.1-1.81.51.6-1.4-1.6-1.41.6-1.4-1.51.61.6-1.6
Pavlov. Cond. latency score1.62.02.4-1.61.41.5-1.2-1.5-1.31.5-1.3-1.41.51.5-1.5
Pavlov. Cond. lever contacts3.54.14.7-2.21.92.0-1.8-2.1-1.92.1-2.0-2.02.12.1-2.1
Pavlov. Cond. magazine entry number2.22.83.51.9-1.6-1.81.61.81.5-1.61.51.5-1.7-1.71.7
Pavlov. Cond. intertrial magazine entries0.40.50.8-0.60.80.8-0.7-0.7-0.90.8-0.7-0.80.60.6-0.6
Pavlov. Cond. lever-magazine prob. diff.2.53.03.9-2.01.71.8-1.6-1.8-1.61.8-1.6-1.61.81.8-1.8
Pavlov. Cond. response bias3.64.45.6-2.42.12.1-1.9-2.2-2.02.1-1.9-2.02.22.2-2.2
Pavlov. Cond. lever latency0.20.30.40.6-0.6-0.40.20.50.5-0.60.60.6-0.5-0.50.5
Pavlov. Cond. magazine entry latency3.13.64.4-2.02.11.7-1.7-2.0-2.01.9-2.0-2.01.81.8-1.8
Pavlov. Cond. change in total contacts0.20.20.4-0.50.50.2-0.0-0.6-0.40.5-0.6-0.60.50.5-0.5
Pavlov. Cond. index score1.41.92.2-1.41.51.2-1.1-1.4-1.41.4-1.5-1.51.31.3-1.3
Pavlov. Cond. latency score1.82.22.6-1.51.61.3-1.2-1.5-1.61.5-1.6-1.61.41.4-1.4
Pavlov. Cond. lever contacts0.20.20.4-0.60.60.3-0.2-0.5-0.50.5-0.6-0.60.50.5-0.5
Pavlov. Cond. magazine entry number1.92.42.91.6-1.7-1.31.21.61.6-1.51.71.7-1.5-1.51.5
Pavlov. Cond. intertrial magazine entries2.63.34.11.8-1.9-1.61.52.01.9-1.91.91.9-1.8-1.81.8
Pavlov. Cond. lever-magazine prob. diff.1.72.12.6-1.51.61.2-1.2-1.5-1.51.5-1.6-1.61.41.4-1.4
Pavlov. Cond. response bias0.50.60.9-1.00.90.5-0.4-0.8-0.80.8-0.9-0.90.70.7-0.7
Time in closed arm before self-admin2.73.04.1-1.81.71.9-2.0-1.7-1.81.9-1.8-1.71.41.5-1.5
Time in closed arm after self-admin0.10.10.3-0.50.10.3-0.0-0.4-0.20.3-0.1-0.20.20.3-0.3
Time in open arm before self-admin0.10.10.3-0.20.30.1-0.4-0.5-0.30.1-0.3-0.20.50.6-0.6
Time in open arm after self-admin0.10.10.40.60.3-0.1-0.50.1-0.2-0.0-0.3-0.1-0.2-0.10.1
Bone: periosteal estimation2.65.37.62.8-2.2-2.52.52.32.3-2.22.22.1-2.2-2.22.2
Bone: periosteal perimeter3.35.46.82.4-2.4-2.52.62.32.4-2.22.22.2-2.2-2.22.2
Bone: post-yield work0.60.91.31.1-0.8-0.90.80.90.7-1.00.90.9-1.0-1.01.0
Progressive ratio test 1 active lever presses0.00.00.1-0.3-0.2-0.00.2-0.10.2-0.10.20.20.10.1-0.1
Progressive ratio test 1 breakpoint0.10.10.3-0.60.20.3-0.1-0.4-0.10.2-0.1-0.00.40.4-0.4
Progressive ratio test 1 inactive lever presses0.00.00.00.10.1-0.10.20.10.0-0.1-0.00.10.1-0.00.0
Progressive ratio test 2 active lever presses0.10.10.30.5-0.0-0.30.10.50.2-0.30.20.3-0.4-0.40.4
Progressive ratio test 2 breakpoint0.10.10.30.5-0.2-0.40.30.50.3-0.40.30.4-0.4-0.30.3
Progressive ratio test 2 inactive lever presses0.00.00.10.20.20.1-0.10.2-0.10.1-0.1-0.10.10.1-0.1
Incentive Sensitization - Responses0.60.71.41.2-0.4-0.90.31.20.5-0.90.50.7-0.9-0.80.8
Incentive Sensitization - Breakpoint0.80.81.61.3-0.5-1.00.51.30.6-1.00.60.8-1.0-1.01.0
Sum of active levers in priming session hrs 5-60.00.00.10.30.20.1-0.20.0-0.20.2-0.4-0.3-0.10.1-0.1
Progressive ratio0.00.00.2-0.30.40.2-0.00.0-0.20.2-0.2-0.20.20.1-0.1
Food seeking constrained by brief footshock0.60.81.40.7-1.0-0.91.20.91.0-0.81.00.9-0.6-0.80.8
Seeking ratio, punishment vs. effort0.20.30.60.6-0.7-0.50.50.40.6-0.50.60.5-0.3-0.40.4
Retroperitoneal fat weight1.03.25.51.2-1.9-1.92.41.82.0-1.81.81.9-1.5-1.51.5
Reaction time number correct1.52.12.6-1.21.31.4-1.3-1.6-1.41.5-1.4-1.51.51.6-1.6
Reaction time mean minus median0.40.50.80.6-0.7-0.30.50.90.7-0.60.80.8-0.6-0.80.8
Reaction time mean minus median AUC0.91.11.61.0-1.0-0.70.71.21.0-1.01.11.1-1.2-1.31.3
Reaction time num false alarms0.00.00.10.3-0.2-0.10.3-0.10.1-0.0-0.00.00.20.2-0.2
Reaction time num false alarms AUC0.00.00.10.3-0.2-0.00.3-0.10.1-0.0-0.00.00.10.2-0.2
Reaction time trials correct on left1.52.12.6-1.21.31.4-1.3-1.6-1.41.5-1.4-1.51.51.6-1.6
Reaction time trials on left1.62.22.7-1.31.31.4-1.3-1.7-1.41.6-1.5-1.51.61.6-1.6
Reaction time mean0.00.00.1-0.30.10.2-0.20.1-0.10.10.1-0.10.1-0.10.1
Reaction time mean AUC0.00.00.1-0.30.10.2-0.30.0-0.10.10.0-0.10.1-0.10.1
Median of all reaction times0.10.10.3-0.50.40.4-0.5-0.2-0.30.4-0.2-0.40.30.2-0.2
Reaction time omissions0.20.30.7-0.50.50.8-0.5-0.6-0.60.6-0.5-0.60.30.5-0.5
Reaction time false alarm rate0.30.40.60.8-0.7-0.60.70.60.7-0.70.60.7-0.6-0.50.5
Reaction time premature initiation rate0.00.00.10.20.2-0.10.20.30.00.10.00.00.20.0-0.0
Reaction time premature initiations0.20.30.7-0.30.60.5-0.4-0.4-0.60.7-0.5-0.60.80.7-0.7
Std. dev. reaction times0.20.30.50.3-0.6-0.20.70.70.6-0.40.70.5-0.5-0.70.7
Reaction time trials completed1.62.22.7-1.31.31.4-1.3-1.7-1.41.6-1.5-1.51.61.6-1.6
Reaction time trials AUC1.21.72.1-1.11.11.2-1.1-1.5-1.21.4-1.3-1.31.41.4-1.4
Run reversals in cocaine runway, females1.51.53.8-2.01.21.1-1.1-1.1-1.11.1-1.0-1.01.31.2-1.2
Run reversals in cocaine runway, males1.41.41.61.1-1.2-1.21.11.11.2-1.31.21.2-1.2-1.11.1
Latency to leave start box in cocaine runway0.40.40.70.8-0.7-0.60.40.40.5-0.60.60.6-0.8-0.70.7
Latency to leave start box in cocaine runway, F0.10.10.20.20.20.2-0.5-0.2-0.40.2-0.3-0.3-0.1-0.10.1
Latency to leave start box in cocaine runway, M1.21.11.71.2-1.3-1.01.20.81.2-1.11.11.1-1.0-0.80.8
Std. dev. time between licks in bursts0.81.01.2-1.01.00.8-0.8-1.0-0.91.0-1.1-1.11.01.0-1.0
Total sessions with >9 infusions0.50.60.90.4-0.7-0.71.00.70.7-0.70.70.7-0.7-0.90.9
Short access day 1 total inactive lever presses2.32.63.51.9-1.8-1.71.61.41.6-1.61.51.5-1.6-1.51.5
Short access day 10 total inactive lever presses2.73.04.02.0-1.9-1.71.61.61.8-1.81.81.7-1.8-1.61.6
Short access day 1 total infusions1.51.62.21.2-1.0-1.31.31.21.1-1.21.11.1-1.4-1.51.5
Short access day 10 total infusions0.10.10.4-0.30.10.30.1-0.4-0.10.3-0.1-0.10.70.6-0.6
Short access total infusions1.01.11.41.0-1.0-1.11.21.01.0-1.01.01.0-1.0-1.11.1
Short access day 1 locomotion0.10.10.30.10.30.1-0.3-0.2-0.30.2-0.5-0.3-0.2-0.20.2
Short access day 10 total locomotion1.31.41.8-0.91.21.2-1.1-1.3-1.21.2-1.3-1.21.31.1-1.1
Short access total locomotion0.10.10.2-0.20.10.30.1-0.3-0.20.3-0.4-0.30.40.2-0.2
One hour access (0.3 mA shock)0.30.40.70.00.80.5-0.7-0.6-0.70.5-0.7-0.50.50.7-0.7
Compulsive drug intake0.50.50.9-0.30.90.7-0.7-0.8-0.80.7-0.9-0.80.50.5-0.5
One hour access (shock baseline)0.10.20.3-0.10.40.3-0.6-0.3-0.40.3-0.4-0.30.30.5-0.5
Social response proportion0.20.20.40.2-0.5-0.50.50.40.4-0.60.50.5-0.6-0.40.4
Social responses0.20.20.5-0.70.30.50.1-0.4-0.40.5-0.5-0.50.40.5-0.5
Social time2.63.44.8-2.21.71.9-1.7-1.8-2.02.0-1.9-2.01.61.7-1.7
Soleus weight0.10.30.50.7-0.4-0.60.10.60.3-0.60.60.6-0.5-0.50.5
Bone: stiffness0.91.42.01.4-1.2-1.21.41.11.2-1.11.11.1-1.1-1.11.1
Tibialis anterior weight0.31.22.1-0.91.01.3-1.4-1.0-1.21.0-1.0-0.91.01.1-1.1
Time to tail flick, vehicle, before self-admin0.10.10.40.1-0.4-0.10.60.20.4-0.20.40.4-0.1-0.20.2
Time to tail flick, vehicle, after self-admin0.40.50.7-0.40.80.8-0.7-0.7-0.80.7-0.8-0.80.60.5-0.5
Time to tail flick, test, before self-admin0.00.00.10.2-0.2-0.20.0-0.00.3-0.20.10.3-0.1-0.20.2
Time to tail flick, test, after self-admin2.93.04.0-1.42.01.7-1.7-1.7-1.91.8-2.0-1.91.41.5-1.5
Delta time to tail flick, vehicle, before/after SA0.10.10.20.50.4-0.0-0.30.1-0.2-0.0-0.4-0.2-0.3-0.40.4
Delta time to tail flick, test, before/after SA3.12.74.0-1.32.01.6-1.6-1.5-1.91.7-1.9-1.91.31.4-1.4
Tibia length0.92.53.71.5-1.6-1.71.91.61.6-1.61.71.6-1.3-1.41.4
Ambulatory time before self-admin0.20.20.80.10.30.1-0.30.5-0.30.1-0.3-0.2-0.8-0.90.9
Ambulatory time after self-admin0.40.40.90.5-0.4-0.60.30.80.3-0.60.50.4-1.0-0.90.9
Bone: tissue strength0.30.30.70.9-0.5-0.70.70.50.5-0.50.40.5-0.5-0.50.5
Total heroin consumption0.30.40.70.8-0.6-0.70.50.40.7-0.70.50.7-0.5-0.40.4
Bone: trabecular number0.10.10.2-0.30.40.1-0.3-0.2-0.30.2-0.3-0.30.30.3-0.3
Bone: trabecular spacing0.60.81.10.8-1.0-0.81.00.90.9-0.90.80.9-0.9-0.90.9
Bone: trabecular thickness0.30.40.9-0.90.60.5-0.5-0.7-0.40.6-0.5-0.60.60.6-0.6
Bone: trabecular tissue density0.71.01.2-0.91.11.1-1.0-1.0-1.01.0-1.0-1.01.11.1-1.1
Water consumed over 24 hours5.06.06.62.5-2.6-2.42.12.42.3-2.52.52.5-2.5-2.52.5
Number of responses in last shaping day0.70.70.9-0.80.80.9-1.0-1.0-0.80.9-1.0-0.80.70.7-0.7