Map4k1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_93418151_93418328 0.01 0.01 2.6e-03 0.01 0.01 0.01 0.01 7.5e-03 9.2e-03 9.6e-03 1.4e-02
2 Adipose alternative TSS NM_001106243.1 0.04 0.03 8.6e-03 0.01 0 0 0.01 1.6e-02 3.0e-01 8.0e-02 4.6e-02
3 Adipose alternative TSS XM_006228716.5 0.04 0.03 7.5e-03 0.01 0 0.01 0.01 1.2e-02 2.3e-01 4.9e-02 2.7e-02
4 BLA intron excision ratio chr1_93418151_93418328 0.04 0.03 9.0e-03 0.04 0.03 0.02 0.03 2.0e-03 8.1e-03 2.0e-02 6.2e-03
5 NAcc isoform ratio XM_008759122.4 0.03 0.02 1.3e-04 0.01 0.01 0.01 0.01 3.3e-03 2.3e-03 3.0e-03 2.3e-03
6 PL isoform ratio NM_001106243.1 0.03 0.02 5.4e-05 0.02 0.02 0.02 0.02 1.7e-03 1.6e-03 1.0e-03 2.1e-03
7 PL isoform ratio XM_008759122.4 0.05 0.04 2.5e-07 0.05 0.05 0.06 0.06 2.2e-06 4.3e-06 9.6e-07 1.1e-06
8 NAcc intron excision ratio chr1_93417855_93418328 0.01 0.01 2.8e-03 0.01 0.01 0.01 0.01 8.5e-03 8.9e-03 5.3e-03 1.4e-02
9 IC intron excision ratio chr1_93417855_93418328 0.06 0.04 4.7e-03 0.04 0.03 0.02 0.04 1.3e-02 2.3e-02 4.2e-02 1.0e-02
10 Adipose gene expression Map4k1 0.08 0.04 9.2e-11 0.05 0.07 0.05 0.06 1.2e-06 4.8e-08 5.0e-06 5.2e-07
11 IC intron excision ratio chr1_93418151_93418328 0.06 0.04 5.8e-03 0.03 0.03 0.01 0.03 1.6e-02 2.6e-02 1.1e-01 1.5e-02
12 pVTA gene expression Map4k1 0.11 0.06 5.6e-10 0.11 0.01 0.12 0.03 3.4e-09 5.8e-02 1.6e-09 1.3e-03
13 IC isoform ratio NM_001106243.1 0.06 0.05 9.7e-03 0.06 0.01 0.05 0.01 1.9e-03 1.8e-01 2.9e-03 1.4e-01
14 IC isoform ratio XM_008759122.4 0.09 0.07 1.0e-03 0.08 0 0.08 0.01 2.5e-04 2.1e-01 3.6e-04 1.4e-01
15 BLA gene expression Map4k1 0.12 0.07 1.0e-08 0.13 0.12 0.12 0.1 1.7e-07 7.2e-07 9.7e-07 7.4e-06
16 Brain intron excision ratio chr1_93417855_93418328 0.04 0.03 3.1e-05 0.04 0.04 0.04 0.04 5.4e-05 1.3e-04 1.8e-04 1.4e-04
17 Brain intron excision ratio chr1_93418151_93418328 0.04 0.03 5.4e-05 0.04 0.04 0.04 0.04 1.1e-04 2.7e-04 2.3e-04 2.2e-04
18 NAcc gene expression Map4k1 0.19 0.09 0.0e+00 0.29 0.27 0.28 0.28 1.4e-43 5.6e-41 5.7e-43 1.0e-42
19 Brain gene expression Map4k1 0.14 0.07 1.1e-16 0.18 0.17 0.19 0.19 7.5e-17 4.1e-16 3.3e-17 3.5e-17
20 IL gene expression Map4k1 0.16 0.09 4.7e-04 0.15 0.15 0.16 0.17 2.4e-04 2.3e-04 1.4e-04 7.9e-05
21 PL gene expression Map4k1 0.21 0.1 0.0e+00 0.26 0.17 0.27 0.13 2.1e-28 4.0e-18 5.9e-29 2.3e-14
22 IC gene expression Map4k1 0.29 0.16 9.1e-10 0.2 -0 0.18 -0 8.7e-09 3.8e-01 7.1e-08 5.4e-01
23 PL intron excision ratio chr1_93417855_93418328 0.07 0.04 3.0e-09 0.08 0.04 0.08 0.06 5.9e-09 1.5e-05 8.2e-09 1.1e-06
24 PL intron excision ratio chr1_93418151_93418328 0.07 0.04 1.9e-09 0.08 0.04 0.08 0.05 2.9e-09 1.2e-05 6.2e-09 8.3e-06
25 OFC gene expression Map4k1 0.18 0.12 5.1e-03 -0.01 0.03 -0.01 0 6.9e-01 5.9e-02 5.7e-01 2.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.00.10.80.20.1-0.10.10.2-0.10.1-0.3-0.1-0.30.10.1-0.20.20.2-0.10.10.10.10.20.20.10.1-0.10.9
Area under the delay curve0.20.21.2-1.1-0.70.7-0.7-0.90.5-0.50.50.30.0-0.2-0.1-0.10.1-0.1-0.10.1-0.10.00.1-0.1-0.10.0-0.0-0.6
BMI with tail0.10.30.90.90.6-0.60.60.4-0.50.5-0.6-0.40.90.40.3-0.20.20.6-0.30.30.60.20.30.50.6-0.30.3-0.7
BMI without tail0.61.72.3-1.1-1.31.3-1.3-1.31.4-1.41.31.4-1.3-1.4-1.41.3-1.3-1.21.4-1.4-1.1-1.5-1.3-1.2-1.11.5-1.5-0.6
Body weight2.310.212.1-2.9-3.33.3-3.3-3.23.4-3.43.23.4-3.5-3.4-3.33.0-3.0-3.23.3-3.3-3.1-3.3-3.0-3.3-3.13.3-3.3-1.0
Weight adjusted by age0.00.00.30.10.2-0.20.20.1-0.10.10.0-0.30.30.2-0.00.2-0.20.0-0.30.30.1-0.1-0.1-0.1-0.10.2-0.2-0.5
Bone surface0.30.61.7-0.8-0.90.9-0.9-0.60.8-0.80.70.7-1.3-0.7-0.70.6-0.6-0.70.7-0.7-0.7-0.8-0.5-0.7-0.71.0-1.00.7
Bone volume0.40.71.7-1.0-1.01.0-1.0-0.70.9-0.90.80.8-1.3-0.8-0.80.7-0.7-0.80.8-0.8-0.8-0.8-0.6-0.7-0.81.0-1.00.6
Breakpoint value in progressive ratio session1.82.17.3-1.6-1.41.4-1.4-1.71.4-1.41.51.5-0.3-1.5-1.31.5-1.5-1.31.3-1.3-1.5-1.3-1.3-1.4-1.51.1-1.1-2.7
Number of licking bursts1.72.84.81.61.9-1.91.91.7-1.81.8-1.6-1.80.81.81.7-1.31.31.5-1.91.91.61.51.31.61.5-1.71.72.2
Context. condit. distance diff. score0.10.10.30.60.4-0.40.40.3-0.30.3-0.4-0.40.30.40.2-0.00.00.4-0.40.40.40.10.10.20.3-0.30.30.0
Locomotion velocity, session 12.32.43.51.01.4-1.41.41.1-1.61.5-1.4-1.71.81.71.6-1.41.41.6-1.91.91.61.71.51.61.7-1.91.90.2
Locomotion distance, session 10.70.91.4-0.7-1.01.0-1.0-1.21.0-1.00.90.9-1.0-0.9-1.01.0-1.0-1.00.9-0.9-1.0-0.9-1.0-1.0-1.00.8-0.8-0.4
Locomotion velocity, session 20.50.51.61.30.9-0.90.90.9-0.80.8-1.0-0.70.70.70.6-0.60.60.7-0.50.50.70.60.60.70.7-0.70.70.3
Locomotion distance, session 20.70.92.31.51.2-1.21.21.1-1.01.1-1.2-0.91.40.90.8-0.80.80.8-0.80.80.70.80.70.80.8-0.80.8-0.6
Locomotion velocity, session 30.30.44.40.60.6-0.60.60.6-0.50.6-0.4-0.5-0.60.50.4-0.30.30.3-0.50.50.20.40.30.30.3-0.40.42.1
Locomotion distance, session 36.26.88.0-2.3-2.52.5-2.5-2.42.7-2.62.72.6-2.8-2.6-2.82.8-2.8-2.62.7-2.7-2.6-2.8-2.8-2.7-2.72.8-2.8-0.7
Stereotopy head waving bouts, day 30.50.61.51.21.0-1.01.01.1-0.90.9-0.9-0.91.10.90.6-0.40.40.5-0.80.80.40.60.40.60.5-0.70.7-0.3
Stereotopy head waving duration, day 32.63.13.81.91.9-1.91.92.0-1.81.9-1.9-1.91.91.91.7-1.61.61.6-1.81.81.61.71.61.81.7-1.71.70.5
Locomotion velocity, session 70.10.10.9-0.1-0.20.2-0.20.00.1-0.10.00.1-0.6-0.1-0.1-0.10.10.00.2-0.2-0.1-0.10.0-0.1-0.00.2-0.20.9
Locomotion distance, session 70.10.20.7-0.3-0.50.5-0.5-0.40.4-0.40.30.4-0.8-0.4-0.40.3-0.3-0.30.4-0.4-0.3-0.4-0.3-0.4-0.40.5-0.50.7
Stereotopy head waving bouts, day 70.30.31.10.60.7-0.70.70.8-0.60.7-0.5-0.61.10.60.4-0.20.20.5-0.50.50.40.30.30.50.4-0.40.4-0.7
Stereotopy head waving duration, day 70.91.12.21.11.2-1.21.21.2-1.11.2-1.0-1.11.51.11.0-0.80.81.0-1.01.00.90.90.81.01.0-0.90.9-0.4
Locomotion velocity, session 83.44.16.82.62.2-2.22.22.2-2.12.1-2.2-2.21.62.21.9-1.71.72.0-2.22.21.91.91.71.91.8-2.02.01.5
Locomotion distance, session 80.50.71.71.31.0-1.01.00.8-0.90.8-0.9-0.91.30.90.6-0.40.40.8-0.90.90.70.60.50.70.7-0.80.8-0.6
Degree of sensitization distance3.33.44.41.61.6-1.61.61.6-1.81.8-1.9-1.81.71.82.0-2.12.12.0-1.91.91.92.12.11.91.9-1.91.91.1
Degree of sensitization stereotypy0.10.10.8-0.10.2-0.20.20.2-0.10.10.1-0.10.50.1-0.10.3-0.3-0.0-0.00.0-0.1-0.2-0.2-0.1-0.10.1-0.1-0.9
Conditioned locomotion0.60.71.90.2-0.20.2-0.2-0.10.5-0.50.60.6-1.3-0.7-1.01.4-1.4-0.90.9-0.9-0.9-1.0-1.4-0.9-1.00.8-0.80.7
Cocaine response after cond. corrected0.50.51.1-0.5-0.70.7-0.7-0.40.7-0.70.60.7-1.0-0.7-0.80.7-0.7-0.70.9-0.9-0.7-0.9-0.7-0.7-0.71.0-1.00.3
Cocaine response after cond. not corrected0.60.71.4-0.2-0.70.7-0.7-0.30.8-0.70.60.8-1.2-0.8-1.00.8-0.8-0.91.0-1.0-1.0-1.0-0.9-1.0-0.91.1-1.10.2
Cocaine response before conditioning1.11.42.4-0.2-0.90.9-0.9-0.71.1-1.00.91.1-0.9-1.1-1.41.3-1.3-1.61.2-1.2-1.5-1.3-1.3-1.4-1.51.2-1.2-1.0
Saline control response0.10.22.2-0.2-0.20.2-0.2-0.30.3-0.30.20.30.4-0.3-0.40.4-0.4-0.30.3-0.3-0.3-0.4-0.4-0.2-0.30.3-0.3-1.5
Bone: connectivity density0.30.51.10.80.6-0.60.60.7-0.60.6-0.8-0.70.30.70.7-0.70.70.8-0.80.80.70.70.70.70.7-0.60.61.0
Bone: cortical apparent density2.43.25.21.51.8-1.81.81.7-1.91.9-1.7-2.02.32.01.9-1.61.61.9-2.02.01.91.81.61.81.8-1.81.8-0.0
Bone: cortical area2.43.84.8-1.8-1.91.9-1.9-1.72.0-1.92.01.9-1.5-1.9-2.02.0-2.0-2.11.9-1.9-2.2-2.0-2.0-2.0-2.22.0-2.0-1.6
Bone: cortical porosity0.50.52.71.71.0-1.01.01.2-0.80.9-1.0-0.80.90.70.4-0.30.30.5-0.40.40.40.40.40.50.5-0.40.4-0.1
Bone: cortical porosity0.70.72.61.61.1-1.11.11.3-0.91.0-1.0-0.90.90.80.6-0.50.50.6-0.60.60.50.60.50.60.6-0.60.60.2
Bone: cortical thickness1.42.43.3-1.2-1.41.4-1.4-1.41.5-1.51.51.4-1.2-1.4-1.71.8-1.8-1.71.4-1.4-1.7-1.6-1.8-1.7-1.81.5-1.5-1.3
Bone: cortical thickness0.10.10.60.80.4-0.40.40.5-0.30.3-0.3-0.3-0.10.3-0.00.1-0.1-0.0-0.20.2-0.00.1-0.10.0-0.1-0.20.20.5
Bone: cortical tissue density2.73.65.51.61.9-1.91.91.8-2.02.0-1.9-2.12.42.12.0-1.81.82.0-2.12.12.01.91.81.91.9-1.91.90.1
Condit. Reinf. active minus inactive responses0.30.30.60.70.6-0.60.60.5-0.60.6-0.6-0.60.30.60.5-0.40.40.4-0.60.60.30.60.40.40.3-0.70.70.8
Condit. Reinf. active-inactive response ratio0.10.20.40.60.5-0.50.50.4-0.50.4-0.4-0.40.40.40.4-0.30.30.3-0.40.40.20.40.30.30.2-0.50.50.2
Condit. Reinf. active responses1.11.42.61.61.4-1.41.41.3-1.31.3-1.3-1.20.81.11.1-1.01.01.1-1.01.00.91.11.11.11.0-1.21.21.2
Condit. Reinf. inactive responses0.81.01.41.21.1-1.11.11.1-1.01.1-1.1-1.00.81.00.9-1.01.01.0-0.80.80.90.91.01.01.0-0.90.90.8
Incentive salience index mean0.10.11.40.60.3-0.30.30.3-0.20.3-0.3-0.2-0.40.20.1-0.10.10.1-0.10.1-0.10.20.10.10.0-0.20.21.2
Condit. Reinf. lever presses0.10.20.7-0.0-0.30.3-0.3-0.10.3-0.30.20.4-0.8-0.4-0.40.3-0.3-0.40.6-0.6-0.5-0.4-0.3-0.4-0.50.4-0.40.8
Condit. Reinf. active minus inactive responses3.95.06.8-2.0-2.12.1-2.1-2.22.2-2.22.32.3-1.9-2.3-2.32.6-2.6-2.32.3-2.3-2.3-2.3-2.6-2.3-2.22.2-2.2-1.6
Condit. Reinf. active-inactive response ratio2.52.94.7-1.0-1.31.3-1.3-1.41.5-1.51.61.7-0.9-1.7-1.82.2-2.2-1.81.8-1.8-1.9-1.9-2.2-1.8-1.71.7-1.7-2.0
Condit. Reinf. active responses4.66.48.2-2.4-2.52.5-2.5-2.62.5-2.62.62.6-2.2-2.6-2.62.9-2.9-2.62.5-2.5-2.6-2.6-2.8-2.5-2.52.4-2.4-1.6
Condit. Reinf. inactive responses1.31.72.9-1.7-1.51.5-1.5-1.61.4-1.41.51.3-1.1-1.3-1.31.2-1.2-1.31.0-1.0-1.3-1.2-1.2-1.3-1.31.0-1.0-0.8
Condit. Reinf. lever presses7.310.114.3-3.6-3.43.4-3.4-3.83.4-3.53.43.3-3.2-3.2-3.23.3-3.3-3.13.0-3.0-3.1-3.0-3.2-3.1-3.02.8-2.8-1.2
Condit. Reinf. lever reinforcers received5.67.89.8-2.6-2.72.7-2.7-2.82.8-2.82.92.8-2.7-2.8-2.93.1-3.1-2.92.8-2.8-2.9-2.9-3.1-2.8-2.82.6-2.6-1.4
Conditioned reinforcement - actives0.10.21.70.50.4-0.40.40.7-0.20.4-0.4-0.5-0.20.40.10.2-0.20.4-0.30.30.4-0.0-0.10.30.4-0.20.21.3
Conditioned reinforcement - inactives0.60.93.1-0.6-0.90.9-0.9-0.61.0-0.80.90.8-1.8-0.8-1.01.1-1.1-0.90.9-0.9-0.9-1.0-1.0-0.9-0.91.0-1.01.2
Conditioned locomotion1.82.44.72.21.9-1.91.92.1-1.61.8-1.7-1.71.31.61.3-0.90.91.5-1.31.31.51.21.11.41.5-1.41.41.4
Patch foraging indifference point 0 sec0.20.30.6-0.3-0.60.6-0.6-0.50.6-0.60.60.4-0.7-0.4-0.70.6-0.6-0.70.3-0.3-0.7-0.6-0.7-0.6-0.70.5-0.50.0
Patch foraging indifference point AUC0.50.82.60.50.7-0.70.70.9-0.80.9-0.8-0.71.60.60.9-1.31.30.8-0.40.40.80.81.30.90.9-0.40.4-1.2
Delay disc. indifference point, 0s delay0.50.52.9-1.1-1.01.0-1.0-1.10.8-0.80.80.50.2-0.5-0.50.1-0.1-0.50.3-0.3-0.5-0.3-0.2-0.5-0.40.4-0.4-1.7
Delay disc. indifference point, 16s delay1.51.63.7-1.9-1.71.7-1.7-1.81.5-1.51.51.2-1.4-1.1-1.21.1-1.1-1.10.9-0.9-1.0-1.0-1.0-1.1-1.01.1-1.1-0.2
Delay disc. indifference point, 2s delay0.10.21.1-1.0-0.40.4-0.4-1.00.2-0.30.4-0.10.10.10.2-0.20.20.2-0.50.50.10.30.20.20.3-0.30.3-0.2
Delay disc. indifference point, 24s delay1.21.43.0-1.7-1.51.5-1.5-1.41.3-1.31.31.3-1.5-1.2-0.90.5-0.5-1.11.1-1.1-1.0-0.9-0.5-1.1-1.01.2-1.20.2
Delay disc. indifference point, 4s delay0.10.10.3-0.5-0.40.4-0.4-0.40.3-0.40.30.2-0.1-0.2-0.30.4-0.4-0.10.0-0.0-0.1-0.2-0.3-0.1-0.10.1-0.1-0.4
Delay disc. indifference point, 8s delay0.81.01.80.30.6-0.60.60.6-0.80.8-0.7-0.91.30.91.1-1.31.31.0-1.21.21.01.21.30.91.0-1.11.1-0.4
Indifference point function ln k0.40.72.3-0.8-0.70.7-0.7-0.90.7-0.80.90.6-1.5-0.6-0.81.2-1.2-0.70.4-0.4-0.7-0.8-1.1-0.7-0.70.4-0.41.2
Indifference point function log k0.40.72.3-0.8-0.70.7-0.7-0.90.7-0.80.90.6-1.5-0.6-0.81.2-1.2-0.70.4-0.4-0.7-0.8-1.1-0.7-0.70.4-0.41.2
Patch foraging total patch changes 0 sec0.20.50.8-0.5-0.70.7-0.7-0.70.7-0.70.70.5-0.9-0.5-0.80.7-0.7-0.70.4-0.4-0.8-0.7-0.8-0.8-0.80.6-0.60.1
Patch foraging total patch changes 12 sec0.20.30.7-0.4-0.60.6-0.6-0.40.6-0.50.50.5-0.1-0.5-0.60.3-0.3-0.50.5-0.5-0.6-0.6-0.4-0.5-0.60.7-0.7-0.8
Patch foraging total patch changes 18 sec0.40.62.80.40.5-0.50.50.9-0.50.7-0.6-0.51.60.50.7-1.11.10.4-0.40.40.40.61.00.60.6-0.40.4-1.7
Patch foraging total patch changes 24 sec0.40.72.0-1.4-1.11.1-1.1-1.00.9-0.90.90.9-0.6-0.9-0.80.3-0.3-0.80.8-0.8-0.9-0.7-0.5-0.7-0.70.8-0.8-0.6
Patch foraging total patch changes 6 sec0.00.10.80.1-0.20.2-0.20.10.3-0.10.10.20.2-0.2-0.2-0.00.0-0.30.3-0.3-0.3-0.20.0-0.2-0.30.3-0.3-0.9
Patch foraging time to switch 0 sec0.81.62.61.31.1-1.11.11.3-1.21.3-1.4-1.21.31.21.3-1.61.61.3-1.21.21.31.41.61.41.3-1.21.20.4
Patch foraging water rate 0 sec0.40.84.40.91.0-1.01.00.9-0.90.9-0.9-0.8-0.10.80.9-0.70.70.7-0.70.70.70.80.60.80.7-0.90.92.1
Patch foraging water rate 12 sec0.61.33.7-1.4-1.21.2-1.2-1.21.1-1.11.41.1-1.9-1.1-0.91.0-1.0-1.21.1-1.1-1.2-0.8-1.0-1.3-1.10.8-0.81.1
Patch foraging water rate 18 sec0.40.74.00.20.7-0.70.70.3-0.80.7-0.6-0.7-0.10.70.9-0.50.50.8-0.80.80.81.00.50.70.8-1.21.22.0
Patch foraging water rate 24 sec0.40.51.6-0.7-0.50.5-0.5-0.60.5-0.60.90.6-1.3-0.6-0.61.0-1.0-0.70.6-0.6-0.7-0.6-0.9-0.8-0.70.3-0.30.9
Patch foraging water rate 6 sec0.20.32.4-1.0-0.40.4-0.4-0.60.3-0.30.60.3-1.2-0.3-0.10.2-0.2-0.30.2-0.2-0.3-0.2-0.2-0.3-0.2-0.00.01.6
Seeking ratio, delayed vs. immediate footshock1.21.42.2-1.5-1.21.2-1.2-1.41.1-1.11.31.3-0.9-1.3-1.11.0-1.0-1.31.2-1.2-1.4-1.2-0.9-1.1-1.21.2-1.2-1.1
Distance traveled before self-admin2.02.73.7-1.4-1.51.5-1.5-1.61.6-1.61.61.8-1.7-1.8-1.71.9-1.9-1.71.8-1.8-1.6-1.8-1.8-1.7-1.61.3-1.3-0.8
Distance traveled after self-admin2.73.34.6-1.7-1.91.9-1.9-1.72.0-1.91.81.9-1.7-1.9-2.02.2-2.2-1.71.8-1.8-1.6-2.0-1.9-1.8-1.61.7-1.7-1.0
Extensor digitorum longus weight0.20.81.01.00.9-0.90.91.0-0.91.0-1.0-1.00.81.00.8-0.60.61.0-1.01.01.00.80.71.00.9-0.90.90.7
Bone: elastic displacement0.00.00.1-0.00.0-0.00.00.0-0.10.1-0.1-0.1-0.00.10.0-0.20.20.2-0.00.00.10.10.20.10.2-0.10.10.3
Bone: elastic work2.63.44.2-1.8-1.91.9-1.9-1.61.9-1.81.81.8-2.0-1.9-2.01.8-1.8-1.91.9-1.9-2.0-1.8-1.8-2.0-2.01.8-1.8-0.4
Bone: endosteal estimation1.12.33.6-1.9-1.81.8-1.8-1.61.7-1.61.61.6-1.0-1.6-1.41.1-1.1-1.41.6-1.6-1.4-1.4-1.1-1.3-1.41.7-1.7-1.6
Bone: endosteal perimeter0.91.93.6-1.9-1.61.6-1.6-1.51.5-1.51.51.5-1.2-1.5-1.21.1-1.1-1.31.5-1.5-1.3-1.3-1.1-1.2-1.31.3-1.3-0.9
Epididymis fat weight0.00.00.10.1-0.10.1-0.10.10.10.0-0.10.0-0.2-0.0-0.20.1-0.10.00.2-0.2-0.0-0.30.00.00.00.2-0.20.4
Delta time in closed arm before/after self-admin0.20.11.5-0.6-0.40.4-0.4-0.50.3-0.30.10.1-0.7-0.1-0.10.1-0.10.2-0.00.00.2-0.00.10.10.20.2-0.21.2
Delta time in open arm before/after self-admin0.10.10.50.30.2-0.20.20.1-0.1-0.00.00.2-0.1-0.3-0.30.7-0.7-0.30.4-0.4-0.5-0.5-0.6-0.3-0.50.1-0.1-0.4
Diff in mean of infusions in LGA sessions0.10.11.4-0.0-0.10.1-0.1-0.20.1-0.00.10.10.5-0.10.2-0.40.4-0.20.0-0.0-0.20.30.4-0.2-0.2-0.30.3-1.2
Delay discount exponential model param0.20.21.31.10.7-0.70.70.9-0.50.5-0.6-0.30.10.20.1-0.00.00.20.1-0.10.10.0-0.10.20.1-0.10.10.6
Extinction: sum of active levers before priming2.22.43.0-1.5-1.61.6-1.6-1.51.6-1.51.61.7-1.0-1.7-1.51.3-1.3-1.71.7-1.7-1.7-1.5-1.3-1.6-1.71.5-1.5-1.7
Active lever presses in extinction session 60.40.41.6-0.8-0.90.9-0.9-0.60.8-0.80.50.60.1-0.6-0.60.5-0.5-0.40.5-0.5-0.5-0.4-0.4-0.5-0.50.5-0.5-1.3
Bone: final force1.72.73.2-1.7-1.71.7-1.7-1.61.7-1.71.81.6-1.5-1.6-1.61.5-1.5-1.81.5-1.5-1.7-1.6-1.6-1.7-1.81.7-1.7-0.9
Bone: final moment2.64.25.0-2.1-2.12.1-2.1-1.92.1-2.12.12.0-2.0-2.0-2.12.0-2.0-2.22.0-2.0-2.2-2.1-2.0-2.1-2.22.1-2.1-1.0
Food consumed during 24 hour testing period0.30.41.3-0.7-0.60.6-0.6-0.70.6-0.60.70.6-1.2-0.6-0.50.5-0.5-0.60.5-0.5-0.6-0.5-0.5-0.6-0.50.4-0.40.8
Glucose0.20.44.4-0.10.2-0.20.20.3-0.30.3-0.3-0.3-0.60.30.5-0.70.70.7-0.30.30.60.50.70.60.6-0.20.22.1
Heart weight0.91.32.2-0.4-1.01.0-1.0-0.71.1-1.10.91.2-1.3-1.2-1.21.2-1.2-1.51.4-1.4-1.3-1.2-1.2-1.3-1.31.4-1.4-0.4
Delay discount hyperbolic model param0.10.10.90.90.5-0.50.50.7-0.30.4-0.4-0.1-0.10.1-0.00.1-0.10.00.3-0.3-0.0-0.1-0.1-0.0-0.10.1-0.10.4
Intermittent access intake day 1-15 change0.30.61.7-1.3-1.01.0-1.0-1.00.9-0.90.90.8-0.7-0.8-0.70.5-0.5-0.50.7-0.7-0.6-0.7-0.6-0.6-0.60.9-0.9-0.3
Intermittent access intake escalation0.20.41.1-1.0-0.80.8-0.8-0.80.6-0.60.70.6-0.4-0.6-0.60.5-0.5-0.40.6-0.6-0.4-0.6-0.5-0.4-0.40.7-0.7-0.4
Intermittent access intake escalation 22.22.54.6-1.6-1.71.7-1.7-1.61.6-1.61.61.6-0.7-1.6-1.51.3-1.3-1.41.7-1.7-1.5-1.6-1.4-1.4-1.51.7-1.7-2.2
Intermitt. access day 1 inactive lever presses1.34.87.1-2.7-2.52.5-2.5-2.52.4-2.42.42.1-2.6-2.1-2.22.0-2.0-2.01.8-1.8-2.0-2.1-2.0-2.0-2.02.2-2.2-0.0
Intermitt. access day 15 inactive lever presses0.61.22.9-1.2-1.21.2-1.2-1.41.2-1.21.11.1-1.7-1.1-1.01.0-1.0-0.91.0-1.0-0.9-0.9-1.0-0.9-0.90.8-0.80.9
Intermitt. access escalation Index0.40.52.6-0.2-0.30.3-0.3-0.70.4-0.60.50.70.1-0.7-0.71.0-1.0-0.70.7-0.7-0.7-0.7-1.0-0.7-0.70.6-0.6-1.6
Intermittent access day 1 total infusions0.40.62.91.21.2-1.21.20.8-1.00.8-0.5-0.5-0.50.50.10.7-0.70.3-0.40.40.30.1-0.50.20.3-0.80.81.7
Intermittent access day 15 total infusions0.20.31.2-0.1-0.10.1-0.1-0.30.1-0.20.40.3-0.9-0.3-0.61.1-1.1-0.40.4-0.4-0.4-0.6-1.0-0.5-0.40.1-0.10.8
Intermittent access terminal intake (last 3 days)0.60.81.8-0.5-0.60.6-0.6-0.60.7-0.70.90.8-1.2-0.9-1.11.3-1.3-1.00.9-0.9-1.0-1.1-1.3-1.0-1.00.7-0.70.2
Intermittent access total infusions0.20.21.70.30.3-0.30.30.1-0.20.00.20.1-0.9-0.1-0.40.9-0.9-0.20.2-0.2-0.2-0.4-0.8-0.3-0.2-0.20.21.3
Intermittent access day 1 locomotion0.20.31.80.40.4-0.40.40.2-0.20.10.1-0.0-0.70.0-0.41.3-1.3-0.20.1-0.1-0.2-0.5-1.2-0.3-0.2-0.10.11.0
Intermittent access day 15 total locomotion0.10.11.20.40.4-0.40.40.4-0.20.3-0.1-0.1-0.40.1-0.00.4-0.40.20.1-0.10.1-0.1-0.30.10.1-0.10.11.1
Intermittent access total locomotion0.30.42.30.80.9-0.90.90.9-0.70.7-0.5-0.6-0.20.60.20.3-0.30.5-0.40.40.40.1-0.20.40.4-0.50.51.5
Intermittent access standard deviation1.73.55.6-2.4-2.12.1-2.1-2.22.0-2.02.21.9-1.1-1.9-1.81.6-1.6-1.81.7-1.7-1.9-1.7-1.7-1.9-1.91.6-1.6-2.3
Left kidney weight3.013.918.7-2.2-3.43.4-3.4-2.93.8-3.63.23.8-3.4-3.8-4.24.0-4.0-4.04.1-4.1-4.0-4.2-3.9-3.8-3.94.3-4.3-2.3
Right kidney weight3.013.917.5-2.6-3.63.6-3.6-3.33.8-3.73.43.8-3.6-3.8-4.13.9-3.9-3.93.9-3.9-3.9-4.2-3.9-3.9-3.94.1-4.1-1.9
Cocaine induced anxiety0.30.41.10.40.3-0.30.30.4-0.30.4-0.6-0.61.00.70.7-0.70.70.6-0.90.90.60.90.80.60.6-0.80.8-0.5
Post-drug Anxiety0.10.10.7-0.4-0.40.4-0.4-0.30.3-0.20.10.00.40.00.0-0.00.00.0-0.20.20.00.20.10.00.0-0.20.2-0.9
Baseline Anxiety1.21.42.4-0.6-0.90.9-0.9-0.90.9-0.91.11.2-1.5-1.3-1.41.4-1.4-1.31.4-1.4-1.3-1.4-1.4-1.3-1.31.4-1.40.1
Tail length5.220.124.7-4.7-5.05.0-5.0-4.44.8-4.74.74.7-4.8-4.7-4.43.9-3.9-4.54.6-4.6-4.4-4.5-4.0-4.4-4.34.7-4.7-1.4
Length with tail6.729.037.3-5.4-5.85.8-5.8-5.45.7-5.75.65.6-6.1-5.6-5.35.0-5.0-5.65.4-5.4-5.4-5.3-5.0-5.4-5.45.5-5.5-1.2
Length without tail1.75.56.9-2.5-2.62.6-2.6-2.62.6-2.52.52.5-2.6-2.4-2.32.0-2.0-2.42.3-2.3-2.4-2.2-1.9-2.4-2.42.2-2.2-0.7
Times rat made contact with spout0.60.71.51.21.0-1.01.01.2-0.91.0-0.9-0.81.20.80.8-0.70.70.6-0.60.60.60.70.70.70.6-0.60.6-0.5
Lifetime Intake0.20.21.80.50.6-0.60.60.4-0.50.4-0.1-0.2-0.60.2-0.10.6-0.60.1-0.00.00.1-0.1-0.6-0.10.1-0.40.41.3
Liver weight, left0.10.20.60.2-0.30.3-0.3-0.10.5-0.40.20.3-0.5-0.3-0.60.6-0.6-0.50.4-0.4-0.5-0.7-0.5-0.4-0.40.8-0.8-0.1
Liver weight, right0.00.10.3-0.1-0.30.3-0.3-0.20.3-0.20.20.3-0.6-0.3-0.20.0-0.0-0.20.4-0.4-0.1-0.1-0.1-0.1-0.10.3-0.30.5
Locomotor activity0.61.01.71.31.0-1.01.01.3-0.91.0-1.2-0.81.20.81.0-1.31.30.8-0.60.60.81.01.30.90.9-0.80.8-0.3
Locomotor testing distance1.22.23.11.41.4-1.41.41.6-1.41.5-1.5-1.51.81.51.5-1.61.61.4-1.41.41.41.51.51.51.5-1.61.60.0
Locomotor testing rearing1.42.87.02.11.8-1.81.81.9-1.71.7-1.9-1.62.71.51.5-1.61.61.4-1.31.31.41.61.41.61.5-1.71.7-1.4
Locomotion in novel chamber0.50.61.60.60.7-0.70.70.5-0.80.7-0.8-0.81.30.80.8-0.80.81.0-0.80.80.90.80.80.90.9-0.90.9-0.5
Locomotion in novel chamber post-restriction0.10.10.6-0.8-0.20.2-0.2-0.60.1-0.10.40.2-0.3-0.20.2-0.60.60.00.0-0.0-0.10.20.4-0.0-0.0-0.30.30.3
Fecal boli incidents, locomotor time 12.43.55.81.51.8-1.81.81.5-1.91.7-1.9-2.01.12.01.8-1.41.42.3-2.12.12.11.81.52.22.2-1.81.82.4
Change in fecal boli incidents, locomotor task0.20.23.90.20.2-0.20.20.2-0.10.1-0.00.11.0-0.10.00.2-0.2-0.20.2-0.2-0.0-0.1-0.0-0.10.0-0.00.0-2.0
Time >=10cm from walls, locomotor time 10.00.00.0-0.00.0-0.00.00.2-0.00.1-0.1-0.1-0.00.10.1-0.00.00.2-0.10.10.10.10.20.10.10.0-0.00.2
Bouts of movement, locomotor time 10.60.62.4-1.6-1.01.0-1.0-1.30.8-1.00.90.9-0.3-0.8-0.50.6-0.6-0.40.6-0.6-0.2-0.5-0.6-0.5-0.30.5-0.5-1.1
Total resting periods, locomotor time 10.40.52.2-1.5-0.80.8-0.8-1.40.6-0.90.70.7-0.3-0.7-0.40.6-0.6-0.20.4-0.4-0.0-0.4-0.6-0.3-0.10.4-0.4-0.6
Rest time, locomotor task time 10.10.10.70.10.4-0.40.4-0.1-0.30.2-0.2-0.2-0.10.20.10.2-0.20.4-0.10.10.40.1-0.20.40.4-0.10.10.8
Distance moved, locomotor task time 10.10.10.60.3-0.20.2-0.20.50.3-0.10.20.20.0-0.3-0.3-0.10.1-0.50.4-0.4-0.6-0.30.1-0.5-0.50.5-0.5-0.8
Vertical activity count, locomotor time 10.51.32.2-0.7-1.01.0-1.0-0.61.1-1.01.11.2-0.6-1.2-1.11.0-1.0-1.31.4-1.4-1.3-1.3-0.9-1.3-1.31.3-1.3-1.5
Time >=10cm from walls, locomotor time 20.00.00.2-0.0-0.20.2-0.20.10.2-0.10.10.10.0-0.1-0.1-0.30.3-0.20.1-0.1-0.3-0.10.3-0.3-0.30.3-0.3-0.5
Bouts of movement, locomotor time 20.20.31.8-0.20.0-0.00.0-0.1-0.30.2-0.4-0.5-0.10.60.5-0.50.50.6-0.80.80.50.60.50.60.7-0.80.81.4
Total resting periods, locomotor time 20.20.41.60.00.2-0.20.20.1-0.40.3-0.5-0.60.00.70.5-0.50.50.6-0.90.90.60.70.50.70.7-0.80.81.3
Rest time, locomotor task time 20.30.40.7-0.5-0.30.3-0.3-0.50.5-0.50.60.6-0.8-0.6-0.60.8-0.8-0.70.6-0.6-0.5-0.7-0.9-0.6-0.60.8-0.80.1
Distance moved, locomotor task time 20.10.20.90.60.2-0.20.20.7-0.20.3-0.4-0.30.80.30.3-0.60.60.2-0.20.20.10.30.60.20.1-0.10.1-0.9
Vertical activity count, locomotor time 20.20.22.4-0.5-0.50.5-0.5-0.40.5-0.50.30.40.4-0.4-0.40.2-0.2-0.20.4-0.4-0.3-0.4-0.1-0.3-0.30.4-0.4-1.6
Light reinforcement 10.20.40.90.40.4-0.40.40.6-0.50.6-0.5-0.60.60.60.7-0.90.90.6-0.60.60.70.80.90.70.5-0.70.70.2
Light reinforcement 26.19.411.32.63.0-3.03.02.7-3.13.0-2.9-3.22.23.23.2-3.03.03.2-3.43.43.33.23.13.13.1-3.33.32.9
Bone: marrow area1.12.43.6-1.9-1.81.8-1.8-1.61.7-1.71.61.7-1.0-1.7-1.41.2-1.2-1.51.6-1.6-1.5-1.5-1.2-1.3-1.41.7-1.7-1.7
Bone: maximum diameter1.52.83.3-1.5-1.71.7-1.7-1.51.7-1.71.71.7-1.8-1.7-1.71.7-1.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.81.8-1.8-0.4
Bone: maximum force3.35.97.1-2.7-2.52.5-2.5-2.42.5-2.52.62.4-1.9-2.4-2.42.4-2.4-2.52.3-2.3-2.5-2.4-2.4-2.4-2.62.4-2.4-1.9
Bone: maximum moment4.47.78.8-3.0-2.92.9-2.9-2.72.9-2.82.92.8-2.3-2.8-2.82.8-2.8-2.82.7-2.7-2.9-2.8-2.7-2.8-3.02.8-2.8-2.0
Mean time between licks in bursts0.10.20.5-0.1-0.30.3-0.3-0.40.4-0.40.50.3-0.6-0.2-0.50.7-0.7-0.60.2-0.2-0.5-0.5-0.7-0.6-0.70.5-0.50.1
Mean num. licks in bursts0.71.15.1-0.5-1.01.0-1.0-0.71.1-1.00.81.10.1-1.1-1.00.7-0.7-1.01.3-1.3-1.0-0.9-0.7-1.0-0.91.1-1.1-2.3
Cd content in liver0.70.82.70.60.9-0.90.90.7-0.90.9-0.7-0.81.60.90.9-1.01.00.8-0.90.90.90.80.90.80.9-0.80.8-1.2
Co content in liver1.01.21.51.21.2-1.21.21.1-1.21.2-1.1-1.20.81.21.0-0.80.81.1-1.21.21.10.90.81.01.0-1.01.01.0
Cu content in liver1.31.54.2-1.1-1.31.3-1.3-1.21.2-1.21.21.2-2.1-1.1-1.31.2-1.2-1.31.0-1.0-1.4-1.2-1.2-1.2-1.41.0-1.01.1
Fe content in liver0.81.02.00.70.8-0.80.80.8-0.90.9-1.0-1.00.51.00.9-1.21.21.2-1.01.01.11.01.21.21.2-1.01.01.4
K content in liver0.70.71.7-0.5-0.80.8-0.8-0.70.9-0.80.70.8-1.3-0.8-1.00.7-0.7-0.90.9-0.9-1.0-0.8-0.8-0.9-1.00.8-0.80.5
Mg content in liver0.20.21.60.3-0.10.1-0.10.10.2-0.10.10.1-1.0-0.2-0.50.3-0.3-0.50.2-0.2-0.5-0.3-0.3-0.3-0.50.3-0.31.3
Mn content in liver0.60.61.30.3-0.30.3-0.3-0.10.6-0.50.50.6-0.7-0.6-1.01.1-1.1-1.00.9-0.9-1.0-1.1-1.1-1.0-1.01.0-1.0-0.4
Na content in liver2.93.14.1-1.4-1.81.8-1.8-1.51.9-1.81.71.8-2.0-1.8-1.91.7-1.7-1.81.9-1.9-1.9-1.8-1.8-1.8-1.91.9-1.9-0.3
Rb content in liver0.00.00.20.3-0.00.0-0.00.20.10.0-0.1-0.0-0.30.0-0.2-0.20.2-0.20.0-0.0-0.10.00.10.0-0.0-0.00.00.5
Se content in liver2.93.45.42.22.2-2.22.22.3-2.02.1-2.0-1.91.81.91.6-1.61.61.8-1.61.61.71.61.61.81.6-1.71.70.9
Sr content in liver0.40.40.80.90.7-0.70.70.6-0.60.6-0.6-0.60.30.60.6-0.40.40.6-0.70.70.70.50.40.50.4-0.60.60.6
Zn content in liver2.52.85.52.31.9-1.91.91.9-1.71.8-1.9-1.60.91.61.4-1.51.51.4-1.51.51.31.51.61.51.3-1.61.62.0
Bone: minimum diameter5.910.714.9-3.0-3.23.2-3.2-3.13.3-3.33.33.4-2.0-3.4-3.23.2-3.2-3.43.4-3.4-3.5-3.3-3.2-3.3-3.43.3-3.3-3.9
Time in familiar zone, hab. session 10.30.30.6-0.4-0.60.6-0.6-0.50.6-0.60.50.5-0.2-0.6-0.50.3-0.3-0.40.6-0.6-0.5-0.5-0.4-0.5-0.50.6-0.6-0.8
Time in novel zone, hab. session 10.10.10.30.50.4-0.40.40.5-0.40.4-0.4-0.40.20.40.3-0.20.20.2-0.40.40.30.30.20.30.3-0.40.40.4
Total zone transitions, hab. session 10.60.84.7-0.6-0.70.7-0.7-0.80.8-0.80.80.80.2-0.8-0.90.9-0.9-0.70.9-0.9-0.7-0.9-0.9-0.8-0.80.9-0.9-2.2
Total locomotion distance, hab. session 13.04.39.9-2.2-2.22.2-2.2-2.32.2-2.22.12.1-0.8-2.1-2.01.9-1.9-1.92.0-2.0-1.9-1.9-1.9-2.0-1.92.0-2.0-3.1
Locomotion velocity, hab. session 11.31.95.9-1.5-1.41.4-1.4-1.61.4-1.41.41.4-0.3-1.4-1.21.2-1.2-1.31.3-1.3-1.2-1.2-1.2-1.3-1.21.2-1.2-2.4
Time in familiar zone, hab. session 20.50.51.2-1.1-0.90.9-0.9-1.10.8-0.90.90.7-0.7-0.7-0.60.7-0.7-0.50.5-0.5-0.5-0.5-0.6-0.7-0.60.6-0.6-0.2
Time in novel zone, hab. session 20.60.60.90.80.8-0.80.81.0-0.80.9-0.8-0.70.70.70.8-0.90.90.6-0.60.60.70.80.80.80.8-0.70.70.3
Total zone transitions, hab. session 20.20.21.21.10.7-0.70.70.8-0.50.5-0.5-0.40.40.40.20.1-0.10.1-0.20.20.10.1-0.10.10.0-0.20.2-0.1
Total locomotion distance, hab. session 20.30.41.2-0.3-0.50.5-0.5-0.50.6-0.60.60.6-0.2-0.7-0.60.8-0.8-0.80.7-0.7-0.8-0.6-0.8-0.8-0.80.6-0.6-1.1
Locomotion velocity, hab. session 20.30.41.1-0.0-0.30.3-0.3-0.30.5-0.40.50.5-0.1-0.6-0.60.8-0.8-0.80.6-0.6-0.7-0.6-0.8-0.7-0.80.5-0.5-1.1
Novel to familiar place preference ratio1.11.23.8-1.2-1.11.1-1.1-1.01.1-1.11.11.2-0.3-1.2-1.00.9-0.9-1.11.2-1.2-1.0-1.1-0.9-1.0-1.01.2-1.2-1.9
Novelty place preference1.01.02.5-1.1-1.11.1-1.1-0.91.1-1.01.01.1-0.4-1.1-0.90.8-0.8-1.01.1-1.1-0.9-1.0-0.8-0.9-0.91.1-1.1-1.6
Time in novel zone, NPP test0.60.62.3-0.9-0.80.8-0.8-0.60.8-0.70.70.8-0.2-0.9-0.70.6-0.6-0.80.9-0.9-0.7-0.8-0.6-0.7-0.70.9-0.9-1.5
Total zone transitions, NPP test0.10.20.30.30.4-0.40.40.2-0.40.4-0.4-0.50.40.50.3-0.20.20.6-0.50.50.60.40.30.50.5-0.50.50.3
Total locomotion distance, NPP test1.72.33.8-1.9-1.71.7-1.7-1.91.6-1.71.71.6-0.8-1.5-1.41.4-1.4-1.41.4-1.4-1.4-1.4-1.4-1.5-1.41.3-1.3-2.0
Locomotion velocity, NPP test2.23.04.4-2.1-1.91.9-1.9-2.11.8-1.91.91.8-1.0-1.7-1.71.7-1.7-1.71.6-1.6-1.6-1.6-1.7-1.7-1.71.5-1.5-2.1
Intraocular pressure0.10.11.1-0.20.1-0.10.1-0.3-0.20.1-0.1-0.1-0.30.10.3-0.30.30.5-0.20.20.50.20.20.40.5-0.20.21.0
Delta distance traveled before/after self-admin0.00.10.1-0.2-0.20.2-0.2-0.10.1-0.0-0.1-0.20.10.20.1-0.20.20.4-0.30.30.30.20.30.40.3-0.00.00.2
Delta ambulatory time before/after self-admin0.10.10.2-0.3-0.40.4-0.4-0.20.4-0.30.20.2-0.1-0.2-0.30.3-0.3-0.20.1-0.1-0.2-0.3-0.2-0.1-0.20.5-0.5-0.3
Parametrial fat weight0.20.41.01.00.8-0.80.81.0-0.70.8-0.7-0.70.30.60.6-0.60.60.5-0.50.50.50.40.60.50.6-0.60.60.8
Pavlov. Cond. lever latency0.30.40.6-0.00.4-0.40.40.2-0.50.4-0.4-0.50.60.60.8-0.80.80.7-0.80.80.70.70.80.70.7-0.70.70.1
Pavlov. Cond. magazine entry latency0.20.20.40.30.5-0.50.50.5-0.60.5-0.4-0.50.30.50.3-0.20.20.5-0.50.50.40.50.30.40.4-0.70.70.6
Pavlov. Cond. change in total contacts0.00.00.10.1-0.00.0-0.00.0-0.00.0-0.00.0-0.2-0.0-0.10.2-0.2-0.00.1-0.1-0.1-0.1-0.1-0.0-0.10.1-0.10.3
Pavlov. Cond. index score0.00.00.20.40.1-0.10.10.3-0.00.1-0.10.0-0.1-0.1-0.30.4-0.4-0.10.2-0.2-0.2-0.2-0.3-0.2-0.20.1-0.10.3
Pavlov. Cond. latency score0.10.10.20.3-0.00.0-0.00.10.1-0.10.10.2-0.3-0.2-0.40.5-0.5-0.30.4-0.4-0.4-0.3-0.4-0.3-0.30.3-0.30.2
Pavlov. Cond. lever contacts0.80.91.3-0.6-0.80.8-0.8-0.70.9-0.90.90.9-1.1-0.9-1.11.1-1.1-1.01.1-1.1-1.1-1.0-1.1-1.0-1.01.0-1.0-0.0
Pavlov. Cond. magazine entry number0.00.00.1-0.1-0.20.2-0.2-0.30.3-0.30.10.2-0.2-0.2-0.0-0.10.1-0.20.2-0.2-0.1-0.2-0.0-0.2-0.10.3-0.3-0.2
Pavlov. Cond. intertrial magazine entries0.20.21.01.00.6-0.60.60.7-0.50.5-0.6-0.40.70.40.4-0.30.30.3-0.30.30.30.30.30.30.3-0.30.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.40.1-0.10.10.30.00.0-0.00.1-0.3-0.1-0.40.5-0.5-0.20.3-0.3-0.3-0.3-0.4-0.2-0.30.2-0.20.3
Pavlov. Cond. response bias0.10.10.2-0.1-0.10.1-0.1-0.00.1-0.10.20.2-0.3-0.2-0.40.5-0.5-0.20.3-0.3-0.3-0.2-0.4-0.2-0.30.1-0.10.4
Pavlov. Cond. lever latency4.05.47.32.62.5-2.52.52.7-2.42.5-2.5-2.42.32.42.4-2.42.42.2-2.22.22.22.22.42.22.2-2.02.01.0
Pavlov. Cond. magazine entry latency2.42.95.6-2.0-1.91.9-1.9-2.11.8-1.91.81.7-2.4-1.6-1.71.7-1.7-1.51.4-1.4-1.5-1.6-1.7-1.6-1.61.4-1.40.7
Pavlov. Cond. change in total contacts5.69.012.3-3.4-3.33.3-3.3-3.53.2-3.23.33.1-2.8-3.1-3.03.0-3.0-2.92.8-2.8-3.0-2.8-3.0-3.0-2.92.6-2.6-1.7
Pavlov. Cond. index score3.95.27.7-2.8-2.62.6-2.6-2.82.4-2.52.52.3-2.5-2.3-2.32.3-2.3-2.12.1-2.1-2.1-2.1-2.3-2.1-2.11.9-1.9-0.4
Pavlov. Cond. latency score3.44.56.8-2.6-2.42.4-2.4-2.62.3-2.32.32.2-2.5-2.1-2.22.1-2.1-1.91.9-1.9-1.9-2.0-2.1-2.0-1.91.8-1.8-0.2
Pavlov. Cond. lever contacts4.46.08.3-2.8-2.72.7-2.7-2.92.6-2.72.62.6-2.4-2.5-2.52.5-2.5-2.32.4-2.4-2.3-2.4-2.4-2.3-2.32.2-2.2-1.1
Pavlov. Cond. magazine entry number1.72.14.52.11.8-1.81.82.0-1.61.7-1.7-1.51.91.41.4-1.31.31.2-1.11.11.21.31.31.31.2-1.11.1-0.3
Pavlov. Cond. intertrial magazine entries1.11.72.51.61.4-1.41.41.5-1.31.4-1.4-1.30.71.31.3-1.41.41.0-1.21.21.01.31.41.21.1-1.11.11.4
Pavlov. Cond. lever-magazine prob. diff.4.05.47.7-2.7-2.62.6-2.6-2.82.5-2.62.52.4-2.6-2.3-2.42.3-2.3-2.12.1-2.1-2.1-2.2-2.3-2.2-2.12.0-2.0-0.4
Pavlov. Cond. response bias5.27.19.4-3.0-2.92.9-2.9-3.12.8-2.92.92.7-2.7-2.7-2.72.8-2.8-2.52.5-2.5-2.6-2.6-2.7-2.6-2.52.3-2.3-1.0
Time in closed arm before self-admin0.10.10.40.70.6-0.60.60.4-0.40.4-0.1-0.30.40.30.4-0.40.4-0.1-0.30.30.00.30.2-0.10.0-0.40.4-0.4
Time in closed arm after self-admin0.10.11.0-0.6-0.30.3-0.3-0.60.2-0.30.40.0-0.70.00.1-0.00.00.0-0.40.40.20.20.0-0.00.2-0.10.11.0
Time in open arm before self-admin1.11.21.7-1.2-1.31.3-1.3-1.01.2-1.21.01.1-1.3-1.1-1.11.0-1.0-1.01.1-1.1-1.0-1.0-0.9-1.0-1.01.1-1.10.2
Time in open arm after self-admin1.61.83.1-0.5-0.90.9-0.9-0.61.1-1.00.91.4-0.8-1.5-1.41.5-1.5-1.51.8-1.8-1.7-1.6-1.4-1.4-1.71.5-1.5-1.4
Bone: periosteal estimation2.45.05.7-2.3-2.42.4-2.4-2.12.4-2.32.32.3-1.6-2.3-2.22.0-2.0-2.32.3-2.3-2.3-2.2-2.0-2.1-2.32.4-2.4-2.1
Bone: periosteal perimeter2.03.54.7-2.2-2.02.0-2.0-1.81.9-1.92.02.0-1.4-2.0-1.81.7-1.7-1.91.9-1.9-1.9-1.8-1.7-1.8-1.91.8-1.8-1.8
Bone: post-yield work1.21.84.1-2.0-1.51.5-1.5-1.61.4-1.41.61.4-0.7-1.3-1.21.3-1.3-1.11.2-1.2-1.2-1.1-1.2-1.2-1.21.1-1.1-1.5
Progressive ratio test 1 active lever presses0.60.72.90.20.1-0.10.1-0.30.1-0.30.50.6-1.3-0.6-1.01.7-1.7-0.70.8-0.8-0.7-1.1-1.6-0.8-0.70.4-0.41.0
Progressive ratio test 1 breakpoint0.80.93.30.0-0.10.1-0.1-0.40.3-0.50.70.8-1.5-0.8-1.11.8-1.8-0.91.0-1.0-0.9-1.2-1.7-0.9-0.90.6-0.60.9
Progressive ratio test 1 inactive lever presses0.71.02.5-0.8-0.80.8-0.8-1.00.9-1.01.00.8-1.6-0.8-1.11.6-1.6-0.80.8-0.8-0.8-1.1-1.5-0.9-0.80.7-0.70.8
Progressive ratio test 2 active lever presses0.20.33.10.50.6-0.60.60.3-0.60.4-0.3-0.3-0.70.20.00.5-0.50.3-0.20.20.3-0.0-0.40.20.3-0.50.51.8
Progressive ratio test 2 breakpoint0.20.32.80.50.6-0.60.60.3-0.60.4-0.3-0.3-0.60.30.10.5-0.50.3-0.20.20.3-0.0-0.40.20.3-0.50.51.7
Progressive ratio test 2 inactive lever presses0.71.13.2-1.3-1.01.0-1.0-1.20.9-1.01.11.0-1.8-0.9-0.91.3-1.3-0.80.8-0.8-0.8-0.9-1.2-0.8-0.80.5-0.51.3
Incentive Sensitization - Responses0.40.61.50.50.6-0.60.60.6-0.80.7-0.7-0.70.20.70.8-0.80.80.7-0.80.80.80.80.80.70.8-0.90.91.2
Incentive Sensitization - Breakpoint0.50.61.30.50.7-0.70.70.6-0.80.8-0.8-0.70.30.70.8-0.90.90.8-0.80.80.80.80.90.80.8-0.90.91.1
Sum of active levers in priming session hrs 5-60.30.34.20.70.4-0.40.40.6-0.20.3-0.3-0.21.30.20.2-0.20.2-0.2-0.20.2-0.30.20.2-0.0-0.3-0.10.1-2.0
Progressive ratio0.50.91.80.10.4-0.40.40.2-0.50.5-0.7-0.91.20.91.0-1.11.11.2-1.11.11.41.11.31.01.1-1.11.1-0.1
Food seeking constrained by brief footshock2.53.15.1-2.1-1.91.9-1.9-2.31.9-2.02.01.8-1.2-1.7-1.71.7-1.7-1.71.6-1.6-1.6-1.7-1.8-1.7-1.71.5-1.5-1.7
Seeking ratio, punishment vs. effort1.31.93.1-1.1-1.11.1-1.1-1.31.1-1.21.41.5-1.8-1.5-1.41.5-1.5-1.61.5-1.5-1.7-1.5-1.7-1.5-1.61.4-1.4-0.0
Retroperitoneal fat weight0.52.02.41.41.4-1.41.41.5-1.41.5-1.5-1.50.91.41.3-1.51.51.3-1.41.41.31.31.51.41.4-1.31.31.4
Reaction time number correct0.00.10.20.30.1-0.10.10.5-0.10.1-0.00.0-0.1-0.1-0.20.4-0.4-0.20.3-0.3-0.3-0.2-0.3-0.2-0.20.1-0.10.0
Reaction time mean minus median0.10.20.5-0.1-0.40.4-0.4-0.40.4-0.40.40.4-0.7-0.4-0.40.3-0.3-0.60.3-0.3-0.6-0.4-0.4-0.5-0.60.3-0.30.3
Reaction time mean minus median AUC0.10.41.3-0.3-0.60.6-0.6-0.50.6-0.60.40.5-1.1-0.5-0.60.6-0.6-0.80.4-0.4-0.9-0.6-0.6-0.6-0.70.5-0.50.7
Reaction time num false alarms1.01.42.91.71.5-1.51.51.3-1.31.3-1.4-1.21.31.21.0-0.80.81.2-1.11.11.10.80.81.21.2-1.01.00.3
Reaction time num false alarms AUC1.32.03.71.91.7-1.71.71.6-1.51.5-1.6-1.51.51.51.2-1.01.01.5-1.41.41.31.01.11.41.4-1.21.20.4
Reaction time trials correct on left0.00.10.20.30.1-0.10.10.5-0.10.1-0.00.0-0.1-0.1-0.20.4-0.4-0.20.3-0.3-0.3-0.2-0.3-0.2-0.20.1-0.10.0
Reaction time trials on left0.00.10.20.40.2-0.20.20.5-0.10.1-0.0-0.0-0.1-0.0-0.10.3-0.3-0.20.3-0.3-0.3-0.2-0.3-0.2-0.20.1-0.10.0
Reaction time mean0.10.11.20.40.3-0.30.30.2-0.30.3-0.3-0.3-0.30.30.3-0.20.20.2-0.40.40.30.30.20.20.3-0.40.41.1
Reaction time mean AUC0.20.32.50.70.6-0.60.60.4-0.50.5-0.6-0.5-0.30.50.4-0.30.30.4-0.60.60.40.40.30.40.4-0.50.51.6
Median of all reaction times0.30.51.50.70.7-0.70.70.5-0.70.6-0.7-0.70.10.70.6-0.50.50.7-0.70.70.70.60.50.60.7-0.70.71.2
Reaction time omissions0.30.41.51.20.8-0.80.80.9-0.70.7-0.9-0.60.40.60.5-0.50.50.6-0.40.40.60.50.50.60.6-0.60.60.5
Reaction time false alarm rate1.01.41.81.31.3-1.31.31.0-1.21.2-1.3-1.21.21.31.1-1.01.01.4-1.31.31.31.01.11.31.3-1.11.10.5
Reaction time premature initiation rate0.00.00.2-0.1-0.00.0-0.0-0.1-0.0-0.00.10.00.2-0.00.00.1-0.1-0.0-0.00.00.00.0-0.0-0.0-0.1-0.30.3-0.4
Reaction time premature initiations0.00.00.10.10.1-0.10.10.3-0.10.10.00.00.2-0.0-0.00.2-0.2-0.10.1-0.1-0.1-0.0-0.2-0.1-0.2-0.30.3-0.3
Std. dev. reaction times0.10.10.70.1-0.20.2-0.2-0.30.2-0.20.20.3-0.8-0.3-0.30.2-0.2-0.50.2-0.2-0.5-0.3-0.4-0.4-0.40.1-0.10.8
Reaction time trials completed0.00.10.20.40.2-0.20.20.5-0.10.1-0.0-0.0-0.1-0.0-0.10.3-0.3-0.20.3-0.3-0.3-0.2-0.3-0.2-0.20.1-0.10.0
Reaction time trials AUC0.00.10.50.60.3-0.30.30.7-0.20.3-0.2-0.10.00.1-0.00.3-0.3-0.10.2-0.2-0.2-0.1-0.2-0.1-0.0-0.10.10.1
Run reversals in cocaine runway, females0.20.22.7-0.00.1-0.10.1-0.0-0.20.1-0.2-0.4-0.50.40.3-0.30.30.4-0.50.50.40.30.20.30.3-0.20.21.6
Run reversals in cocaine runway, males1.41.42.21.51.5-1.51.51.5-1.41.4-1.2-1.01.11.01.1-1.31.30.9-0.90.91.01.11.20.90.9-1.21.20.2
Latency to leave start box in cocaine runway0.00.10.20.20.0-0.00.00.3-0.00.1-0.2-0.30.10.30.2-0.30.30.3-0.30.30.30.20.50.20.1-0.00.00.3
Latency to leave start box in cocaine runway, F0.40.40.90.80.6-0.60.60.9-0.50.7-0.7-0.70.60.70.6-0.80.80.5-0.70.70.50.60.90.50.4-0.50.50.2
Latency to leave start box in cocaine runway, M0.20.10.4-0.6-0.50.5-0.5-0.50.5-0.50.40.3-0.4-0.3-0.20.5-0.50.10.2-0.20.0-0.3-0.3-0.2-0.10.4-0.40.2
Std. dev. time between licks in bursts0.50.71.2-1.1-0.90.9-0.9-1.00.9-0.91.00.6-0.4-0.6-0.80.9-0.9-0.70.5-0.5-0.7-0.9-0.9-0.8-0.90.9-0.9-1.1
Total sessions with >9 infusions0.70.82.31.51.5-1.51.51.2-1.41.1-0.8-0.80.90.80.40.3-0.30.5-0.50.50.60.2-0.30.60.6-0.70.7-0.1
Short access day 1 total inactive lever presses0.70.92.2-1.5-1.31.3-1.3-1.31.1-1.11.20.8-1.3-0.7-0.90.9-0.9-0.80.5-0.5-0.8-0.7-0.9-0.8-0.80.6-0.60.5
Short access day 10 total inactive lever presses1.33.27.3-2.7-2.42.4-2.4-2.32.3-2.12.11.6-2.1-1.6-1.61.4-1.4-1.51.3-1.3-1.5-1.5-1.3-1.5-1.51.6-1.60.1
Short access day 1 total infusions0.50.71.8-0.4-0.30.3-0.3-0.60.3-0.50.80.8-0.9-0.8-1.01.3-1.3-1.01.0-1.0-0.9-1.0-1.3-0.9-0.90.6-0.6-0.1
Short access day 10 total infusions0.20.20.60.80.8-0.80.80.5-0.60.5-0.3-0.4-0.00.40.10.2-0.20.1-0.20.20.10.1-0.30.00.1-0.50.50.6
Short access total infusions0.20.30.80.80.9-0.90.90.5-0.80.6-0.3-0.40.00.40.00.6-0.60.2-0.20.20.20.0-0.60.20.2-0.60.60.7
Short access day 1 locomotion1.21.53.31.81.5-1.51.51.8-1.31.4-1.5-1.31.41.31.0-0.70.71.1-1.01.01.10.90.81.31.1-1.01.00.3
Short access day 10 total locomotion0.61.12.4-0.9-0.90.9-0.9-0.91.1-1.11.00.8-0.7-0.8-1.21.5-1.5-0.90.8-0.8-1.0-1.3-1.5-1.0-1.00.9-0.9-0.9
Short access total locomotion0.20.20.80.80.6-0.60.60.7-0.40.3-0.3-0.40.50.4-0.20.9-0.90.1-0.10.10.0-0.3-0.80.10.0-0.20.2-0.4
One hour access (0.3 mA shock)0.60.61.1-1.0-0.80.8-0.8-1.00.9-0.91.00.7-0.9-0.7-0.81.1-1.1-0.60.7-0.7-0.6-0.8-1.0-0.7-0.60.6-0.60.1
Compulsive drug intake2.63.18.2-2.0-1.81.8-1.8-1.92.0-1.91.91.8-0.6-1.7-1.61.4-1.4-1.71.6-1.6-1.6-1.7-1.4-1.6-1.61.7-1.7-2.9
One hour access (shock baseline)0.10.22.10.10.3-0.30.30.2-0.40.2-0.1-0.2-0.50.20.10.3-0.30.3-0.10.10.30.1-0.20.20.3-0.40.41.4
Social response proportion3.64.15.6-0.8-1.81.8-1.8-1.82.0-2.01.92.2-2.1-2.2-2.12.2-2.2-2.32.3-2.3-2.3-2.1-2.3-2.4-2.12.0-2.0-1.1
Social responses0.10.10.60.2-0.30.3-0.3-0.30.3-0.30.10.3-0.8-0.3-0.20.2-0.2-0.20.3-0.3-0.3-0.2-0.2-0.3-0.10.3-0.30.7
Social time0.50.61.8-1.1-1.01.0-1.0-1.40.9-1.00.80.9-0.4-0.9-0.60.5-0.5-0.60.7-0.7-0.6-0.5-0.6-0.5-0.50.6-0.6-1.2
Soleus weight0.72.04.60.71.3-1.31.30.9-1.41.3-1.2-1.52.11.51.4-1.31.31.5-1.61.61.61.41.41.61.6-1.51.5-0.8
Bone: stiffness1.62.63.3-1.8-1.71.7-1.7-1.71.7-1.71.81.6-1.0-1.5-1.61.7-1.7-1.61.4-1.4-1.6-1.6-1.7-1.6-1.71.6-1.6-1.8
Tibialis anterior weight0.10.22.40.50.3-0.30.30.1-0.20.2-0.3-0.11.00.1-0.00.3-0.30.20.0-0.00.2-0.1-0.20.20.2-0.00.0-1.6
Time to tail flick, vehicle, before self-admin0.10.10.90.70.2-0.20.20.8-0.10.3-0.2-0.1-0.50.0-0.20.1-0.1-0.20.3-0.3-0.2-0.2-0.1-0.1-0.20.1-0.11.0
Time to tail flick, vehicle, after self-admin0.50.72.2-1.2-0.90.9-0.9-1.00.8-0.91.00.8-1.5-0.8-0.60.8-0.8-0.50.6-0.6-0.4-0.6-0.6-0.7-0.40.6-0.61.0
Time to tail flick, test, before self-admin0.30.30.60.80.4-0.40.40.8-0.40.6-0.7-0.60.50.60.5-0.70.70.4-0.50.50.50.60.70.50.5-0.30.30.4
Time to tail flick, test, after self-admin0.10.10.40.50.2-0.20.20.4-0.20.2-0.4-0.40.10.40.1-0.00.00.2-0.40.40.10.30.10.30.1-0.10.10.6
Delta time to tail flick, vehicle, before/after SA0.50.41.0-1.0-0.70.7-0.7-1.00.6-0.70.80.7-0.8-0.6-0.50.7-0.7-0.50.5-0.5-0.4-0.6-0.6-0.6-0.40.7-0.70.1
Delta time to tail flick, test, before/after SA0.00.00.10.10.1-0.10.1-0.10.0-0.10.00.1-0.3-0.1-0.20.3-0.3-0.10.2-0.2-0.2-0.1-0.4-0.1-0.20.0-0.00.4
Tibia length1.95.47.3-2.0-2.42.4-2.4-2.22.4-2.42.32.4-2.7-2.4-2.42.2-2.2-2.52.5-2.5-2.6-2.3-2.2-2.4-2.42.3-2.3-0.3
Ambulatory time before self-admin1.42.02.6-1.4-1.41.4-1.4-1.51.4-1.51.51.6-1.3-1.6-1.51.6-1.6-1.41.6-1.6-1.4-1.5-1.5-1.5-1.41.2-1.2-1.0
Ambulatory time after self-admin2.93.44.0-2.0-2.02.0-2.0-1.92.0-2.01.91.9-1.8-1.9-1.91.9-1.9-1.71.8-1.8-1.6-1.9-1.9-1.7-1.61.7-1.7-1.0
Bone: tissue strength4.95.06.0-2.5-2.42.4-2.4-2.32.3-2.32.42.2-2.0-2.2-2.32.3-2.3-2.22.2-2.2-2.2-2.3-2.2-2.3-2.22.3-2.3-1.4
Total heroin consumption1.21.48.2-0.9-0.80.8-0.8-1.01.0-1.01.01.10.2-1.1-1.11.4-1.4-1.21.0-1.0-1.3-1.1-1.2-1.2-1.30.9-0.9-2.9
Bone: trabecular number0.10.20.5-0.2-0.50.5-0.5-0.40.5-0.40.20.4-0.7-0.4-0.40.3-0.3-0.40.4-0.4-0.4-0.4-0.3-0.4-0.40.4-0.40.4
Bone: trabecular spacing1.82.43.0-1.6-1.51.5-1.5-1.51.5-1.61.71.6-0.9-1.6-1.61.6-1.6-1.51.6-1.6-1.5-1.5-1.6-1.6-1.51.4-1.4-1.7
Bone: trabecular thickness0.20.31.80.80.5-0.50.50.7-0.50.5-0.6-0.5-0.30.50.4-0.40.40.3-0.40.40.30.40.40.40.3-0.30.31.3
Bone: trabecular tissue density2.33.44.31.61.8-1.81.81.8-1.91.9-1.9-2.02.02.02.0-2.12.11.9-2.02.01.81.82.01.92.0-1.71.70.5
Water consumed over 24 hours0.60.81.3-0.1-0.60.6-0.6-0.40.8-0.70.70.9-1.1-0.9-1.01.1-1.1-1.11.0-1.0-1.0-1.1-1.1-1.0-1.11.0-1.00.0
Number of responses in last shaping day0.40.40.7-0.2-0.30.3-0.3-0.50.3-0.40.50.8-0.7-0.8-0.60.4-0.4-0.80.9-0.9-0.9-0.7-0.6-0.8-0.90.7-0.7-0.3