Hub : Genes

Map4k1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS NM_001106243.1 0.04 0.03 6.0e-03 0.01 0 0.01 0.01 2.0e-02 2.8e-01 4.0e-02 6.0e-02
2 Adipose alternative TSS NM_001106243.1 0.04 0.03 5.1e-03 0.01 0 0.01 0.01 2.0e-02 2.7e-01 3.6e-02 5.2e-02
3 Adipose alternative TSS XM_006228716.4 0.04 0.03 5.0e-03 0.01 0 0.01 0.01 1.6e-02 2.0e-01 2.8e-02 3.9e-02
4 BLA intron excision ratio chr1_84290651_84290828 0.04 0.03 9.8e-03 0.05 0.04 0.04 0.03 1.4e-03 4.4e-03 2.7e-03 6.9e-03
5 Adipose alternative TSS XM_006228716.4 0.04 0.03 4.4e-03 0.01 0 0.01 0.01 1.6e-02 2.1e-01 2.6e-02 4.0e-02
6 BLA mRNA stability Map4k1 0.07 0.05 5.1e-05 0.06 0.08 0.08 0.08 2.4e-04 4.2e-05 3.4e-05 6.7e-05
7 NAcc mRNA stability Map4k1 0.04 0.02 1.6e-05 0.03 0.04 0.03 0.04 2.6e-04 2.5e-05 2.5e-04 2.2e-05
8 Brain intron excision ratio chr1_84290355_84290828 0.04 0.03 2.7e-05 0.06 0.05 0.04 0.05 7.7e-06 3.2e-05 4.7e-05 3.2e-05
9 Brain intron excision ratio chr1_84290651_84290828 0.04 0.03 4.4e-05 0.05 0.04 0.04 0.04 1.1e-05 6.5e-05 2.6e-04 4.6e-05
10 OFC mRNA stability Map4k1 0.13 0.09 9.4e-03 0.05 0.02 0 0.04 2.3e-02 1.0e-01 3.1e-01 4.7e-02
11 PL intron excision ratio chr1_84290651_84290828 0.07 0.04 2.2e-09 0.08 0.08 0.07 0.07 5.6e-09 4.3e-09 5.7e-08 1.6e-08
12 Brain gene expression Map4k1 0.14 0.07 0.0e+00 0.2 0.17 0.18 0.19 2.0e-18 1.0e-15 1.0e-16 1.9e-17
13 IL gene expression Map4k1 0.18 0.1 1.2e-04 0.19 0.17 0.16 0.19 2.0e-05 5.5e-05 1.2e-04 2.0e-05
14 PL gene expression Map4k1 0.19 0.09 0.0e+00 0.28 0.26 0.24 0.27 3.1e-30 1.4e-28 5.7e-26 3.5e-29
15 PL intron excision ratio chr1_84290355_84290828 0.07 0.04 3.3e-09 0.08 0.08 0.07 0.07 1.1e-08 9.5e-09 1.0e-07 1.8e-08
16 pVTA gene expression Map4k1 0.24 0.13 6.5e-09 0.18 0.16 0.2 0.17 2.4e-08 3.2e-07 3.0e-09 1.0e-07
17 NAcc gene expression Map4k1 0.13 0.07 0.0e+00 0.2 0.18 0.19 0.2 2.7e-22 5.9e-21 2.1e-21 4.3e-22
18 IL mRNA stability Map4k1 0.11 0.08 6.4e-03 0.1 0.08 0.08 0.06 1.8e-03 6.1e-03 5.9e-03 1.2e-02
19 Adipose gene expression Map4k1 0.09 0.05 1.6e-11 0.07 0.07 0.07 0.07 9.8e-09 1.2e-08 2.5e-08 1.9e-08
20 pVTA mRNA stability Map4k1 0.06 0.05 4.1e-03 0.06 0.03 0.04 0.05 2.1e-03 2.1e-02 5.1e-03 4.6e-03
21 Adipose mRNA stability Map4k1 0.17 0.09 0.0e+00 0.12 0.13 0.12 0.12 2.0e-13 5.5e-14 1.7e-13 1.4e-13
22 PL mRNA stability Map4k1 0.21 0.1 0.0e+00 0.25 0.24 0.24 0.26 3.5e-27 1.8e-26 1.5e-26 2.3e-28
23 Brain mRNA stability Map4k1 0.09 0.06 1.1e-08 0.09 0.08 0.09 0.09 7.5e-09 5.6e-08 1.4e-08 1.3e-08
24 BLA gene expression Map4k1 0.13 0.07 5.0e-09 0.16 0.15 0.12 0.16 4.8e-09 2.9e-08 9.7e-07 1.2e-08
25 OFC gene expression Map4k1 0.16 0.11 8.5e-03 -0 0.03 0.04 0.01 3.9e-01 7.4e-02 5.1e-02 1.8e-01
26 NAcc alternative TSS NM_001106243.1 0.08 0.07 8.9e-03 0 0.01 0.01 0 1.4e-01 1.8e-02 1.4e-02 1.6e-01
27 NAcc alternative TSS NM_001106243.1 0.08 0.06 8.2e-03 0 0.01 0.01 0 1.2e-01 2.5e-02 8.9e-03 1.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.10.10.6-0.3-0.30.3-0.30.30.3-0.20.2-0.20.20.6-0.30.4-0.4-0.6-0.3-0.40.2-0.20.4-0.2-0.20.6-0.2-0.80.50.5
Area under the delay curve0.40.43.70.60.6-0.60.6-0.6-0.2-0.1-0.50.5-0.5-0.4-0.20.20.00.4-0.10.00.2-0.10.1-0.20.1-0.0-0.10.6-1.9-1.9
BMI with tail0.10.30.7-0.8-0.80.8-0.80.80.6-0.80.6-0.60.60.5-0.40.4-0.6-0.5-0.5-0.60.4-0.50.4-0.6-0.60.6-0.60.1-0.2-0.1
BMI without tail0.20.41.10.60.6-0.60.6-0.6-0.70.2-0.70.7-0.7-0.70.7-0.90.40.70.70.4-0.80.8-0.80.50.7-0.60.71.1-0.5-0.4
Body weight2.510.513.03.53.5-3.53.5-3.5-3.33.6-3.63.6-3.6-3.13.0-3.03.33.03.33.3-2.93.5-3.43.53.6-3.13.52.41.61.7
Weight adjusted by age0.10.10.3-0.5-0.50.5-0.50.50.3-0.40.4-0.40.40.4-0.30.3-0.3-0.3-0.3-0.30.2-0.40.5-0.4-0.30.3-0.3-0.20.40.4
Bone surface0.30.51.00.70.7-0.70.7-0.7-0.70.8-0.80.8-0.8-0.30.6-0.50.50.20.70.5-0.80.7-0.50.80.8-0.40.8-0.31.01.0
Bone volume0.30.51.00.70.7-0.70.7-0.7-0.70.8-0.70.7-0.7-0.30.7-0.60.50.20.70.5-0.80.7-0.50.80.8-0.30.8-0.31.01.0
Breakpoint value in progressive ratio session1.61.75.11.41.4-1.41.4-1.4-1.30.8-1.01.0-1.0-1.91.2-1.21.32.01.21.3-1.11.3-1.30.71.1-1.21.02.3-1.1-1.1
Number of licking bursts2.22.65.9-1.8-1.81.8-1.81.81.6-1.11.7-1.71.71.9-1.31.3-1.5-2.0-1.5-1.51.3-1.81.7-1.2-1.61.4-1.6-2.40.60.5
Context. condit. distance diff. score0.10.10.2-0.3-0.30.3-0.30.30.3-0.30.3-0.30.30.2-0.30.3-0.1-0.2-0.3-0.10.3-0.30.3-0.3-0.30.2-0.3-0.20.40.4
Locomotion velocity, session 12.32.53.4-1.5-1.51.5-1.51.51.6-1.81.7-1.71.71.4-1.71.6-1.6-1.4-1.7-1.61.7-1.81.6-1.8-1.81.6-1.8-0.9-1.3-1.3
Locomotion distance, session 10.81.01.31.11.1-1.11.1-1.1-1.01.0-1.01.0-1.0-1.01.0-1.01.01.01.01.0-0.81.0-1.01.01.0-1.01.00.70.00.1
Locomotion velocity, session 20.30.40.6-0.7-0.70.7-0.70.70.8-0.80.6-0.60.60.6-0.70.7-0.6-0.6-0.6-0.60.7-0.50.5-0.6-0.50.6-0.5-0.2-0.2-0.1
Locomotion distance, session 20.40.61.1-1.0-1.01.0-1.01.00.9-1.00.8-0.80.80.6-0.70.8-0.8-0.5-0.8-0.80.9-0.70.7-0.9-0.70.7-0.70.2-0.2-0.2
Locomotion velocity, session 30.40.53.3-0.7-0.70.7-0.70.70.50.10.6-0.60.61.0-0.30.3-0.3-1.1-0.4-0.30.4-0.50.30.1-0.50.3-0.5-1.81.21.2
Locomotion distance, session 35.76.27.82.42.4-2.42.4-2.4-2.62.8-2.62.6-2.6-2.32.6-2.62.72.22.72.7-2.62.7-2.62.82.7-2.72.71.51.61.7
Stereotopy head waving bouts, day 30.70.82.2-1.3-1.31.3-1.31.30.9-0.71.0-1.01.00.6-0.50.5-0.5-0.6-0.6-0.50.5-0.90.6-0.7-0.90.5-0.9-0.31.51.4
Stereotopy head waving duration, day 32.63.14.3-2.1-2.12.1-2.12.11.9-1.81.9-1.91.91.7-1.61.7-1.7-1.7-1.7-1.71.7-1.91.7-1.8-1.91.8-1.8-1.30.30.2
Locomotion velocity, session 70.00.00.30.10.1-0.10.1-0.10.00.2-0.10.1-0.10.3-0.10.10.0-0.3-0.00.00.10.2-0.00.20.00.10.0-0.60.30.3
Locomotion distance, session 70.10.10.30.30.3-0.30.3-0.3-0.40.5-0.30.3-0.3-0.10.3-0.30.30.00.30.3-0.40.4-0.30.50.3-0.30.3-0.20.50.6
Stereotopy head waving bouts, day 70.10.10.9-0.5-0.50.5-0.50.50.3-0.30.2-0.20.20.1-0.10.1-0.0-0.1-0.1-0.00.1-0.10.1-0.2-0.20.1-0.10.11.01.0
Stereotopy head waving duration, day 70.91.11.8-1.3-1.31.3-1.31.31.2-1.21.1-1.11.10.9-1.01.0-0.9-0.8-1.0-0.90.9-1.01.0-1.1-1.01.0-1.0-0.30.30.2
Locomotion velocity, session 83.13.75.0-2.2-2.22.2-2.22.22.1-1.82.1-2.12.12.1-1.81.9-1.7-2.1-1.9-1.71.8-2.01.9-1.7-2.01.8-2.0-1.90.70.6
Locomotion distance, session 80.30.40.9-0.8-0.80.8-0.80.80.7-1.00.7-0.70.70.4-0.70.7-0.5-0.3-0.6-0.50.7-0.70.7-0.8-0.70.5-0.70.20.00.1
Degree of sensitization distance3.33.34.0-1.7-1.71.7-1.71.71.9-1.91.9-1.91.91.8-1.92.0-2.0-1.8-2.0-2.01.9-2.01.9-2.0-2.02.0-2.0-1.4-1.1-1.1
Degree of sensitization stereotypy0.10.10.4-0.3-0.30.3-0.30.30.0-0.20.0-0.00.0-0.20.0-0.00.10.20.10.1-0.10.1-0.0-0.10.1-0.10.10.50.60.6
Conditioned locomotion0.70.85.70.10.1-0.10.1-0.1-0.61.1-0.60.6-0.6-0.20.9-0.90.80.10.80.8-0.90.7-0.81.10.8-0.80.8-0.52.42.3
Cocaine response after cond. corrected0.40.50.80.50.5-0.50.5-0.5-0.70.8-0.70.7-0.7-0.40.8-0.80.70.40.70.7-0.80.8-0.60.90.7-0.80.80.00.80.8
Cocaine response after cond. not corrected0.80.92.50.60.6-0.60.6-0.6-0.91.1-0.90.9-0.9-0.61.1-1.10.90.51.00.9-1.21.0-0.81.10.9-1.00.90.31.61.6
Cocaine response before conditioning1.72.14.81.01.0-1.01.0-1.0-1.51.5-1.31.3-1.3-1.41.7-1.61.61.41.61.6-1.81.3-1.41.51.3-1.51.31.52.22.2
Saline control response0.50.72.50.70.7-0.70.7-0.7-0.90.4-0.80.8-0.8-1.11.0-1.00.71.20.80.7-0.90.8-0.70.40.8-0.70.81.6-0.1-0.1
Bone: connectivity density0.50.81.3-0.8-0.80.8-0.80.80.9-0.80.8-0.80.81.1-1.01.0-1.0-1.1-0.9-1.00.9-0.81.1-0.8-0.71.1-0.7-1.1-0.3-0.3
Bone: cortical apparent density2.02.73.8-1.8-1.81.8-1.81.81.8-2.01.8-1.81.81.4-1.71.7-1.7-1.3-1.7-1.71.7-1.71.6-1.9-1.71.7-1.7-0.5-0.7-0.7
Bone: cortical area2.13.23.71.71.7-1.71.7-1.7-1.91.8-1.81.8-1.8-1.91.9-1.91.91.91.91.9-1.91.8-1.81.81.8-1.71.81.71.51.5
Bone: cortical porosity0.80.81.6-1.3-1.31.3-1.31.31.0-0.80.9-0.90.90.9-0.90.8-0.7-0.9-0.7-0.70.7-0.70.7-0.7-0.80.7-0.7-0.51.01.0
Bone: cortical porosity0.90.91.9-1.4-1.41.4-1.41.41.1-0.80.9-0.90.91.0-0.90.8-0.7-1.0-0.8-0.70.8-0.80.8-0.7-0.80.7-0.8-0.51.11.1
Bone: cortical thickness1.01.62.41.11.1-1.11.1-1.1-1.31.2-1.11.1-1.1-1.31.4-1.41.41.31.31.4-1.31.2-1.31.21.2-1.21.21.11.51.6
Bone: cortical thickness0.30.32.5-0.7-0.70.7-0.70.70.4-0.00.3-0.30.30.5-0.20.2-0.0-0.5-0.2-0.00.2-0.30.2-0.0-0.20.1-0.2-0.41.61.6
Bone: cortical tissue density2.43.24.4-1.9-1.91.9-1.91.91.9-2.11.9-1.91.91.6-1.81.8-1.8-1.5-1.8-1.81.9-1.81.7-2.0-1.91.9-1.9-0.7-0.8-0.8
Condit. Reinf. active minus inactive responses0.30.30.7-0.6-0.60.6-0.60.60.5-0.30.7-0.70.70.6-0.40.4-0.3-0.6-0.5-0.30.4-0.70.6-0.4-0.70.4-0.7-0.80.60.5
Condit. Reinf. active-inactive response ratio0.30.31.0-0.6-0.60.6-0.60.60.4-0.30.6-0.60.60.4-0.30.4-0.2-0.4-0.4-0.20.2-0.70.5-0.4-0.60.2-0.6-0.71.00.9
Condit. Reinf. active responses1.01.21.7-1.3-1.31.3-1.31.31.2-1.01.2-1.21.21.3-1.11.1-1.0-1.3-1.1-1.01.1-1.11.2-1.0-1.11.0-1.1-1.10.20.1
Condit. Reinf. inactive responses0.60.81.1-0.9-0.90.9-0.90.91.0-0.90.7-0.70.71.0-1.00.9-1.0-1.0-0.9-1.01.0-0.60.8-0.8-0.81.0-0.7-0.5-0.8-0.8
Incentive salience index mean0.10.10.5-0.2-0.20.2-0.20.20.10.20.2-0.20.20.4-0.10.10.0-0.5-0.10.00.0-0.20.20.1-0.20.0-0.2-0.70.70.7
Condit. Reinf. lever presses0.10.20.30.40.4-0.40.4-0.4-0.40.5-0.50.5-0.5-0.20.3-0.30.40.10.40.4-0.30.5-0.30.60.5-0.40.50.00.20.3
Condit. Reinf. active minus inactive responses4.15.16.52.22.2-2.22.2-2.2-2.52.3-2.22.2-2.2-2.42.5-2.52.42.42.42.4-2.52.3-2.42.32.2-2.52.12.01.11.2
Condit. Reinf. active-inactive response ratio2.83.04.01.31.3-1.31.3-1.3-1.81.6-1.61.6-1.6-1.92.0-1.91.92.01.91.9-1.91.7-2.01.71.7-2.01.72.01.61.6
Condit. Reinf. active responses4.66.48.12.62.6-2.62.6-2.6-2.82.6-2.52.5-2.5-2.62.8-2.82.72.62.72.7-2.82.6-2.72.52.4-2.72.42.31.01.0
Condit. Reinf. inactive responses1.51.82.81.71.7-1.71.7-1.7-1.51.3-1.41.4-1.4-1.41.3-1.41.31.41.31.3-1.41.3-1.21.21.2-1.21.21.4-0.4-0.4
Condit. Reinf. lever presses6.69.011.93.43.4-3.43.4-3.4-3.43.2-3.03.0-3.0-3.03.3-3.23.12.93.13.1-3.22.9-3.13.02.8-3.12.72.30.00.2
Condit. Reinf. lever reinforcers received5.57.79.82.82.8-2.82.8-2.8-3.12.9-2.82.8-2.8-2.83.1-3.12.92.73.02.9-3.12.8-3.02.92.7-3.02.62.21.31.4
Conditioned reinforcement - actives0.40.41.20.40.4-0.40.4-0.4-0.80.7-0.70.7-0.7-0.21.0-1.00.50.20.70.5-1.10.5-0.50.70.6-0.60.6-0.00.50.6
Conditioned reinforcement - inactives1.92.13.21.51.5-1.51.5-1.5-1.41.8-1.41.4-1.4-1.31.3-1.41.51.21.51.5-1.31.6-1.51.81.5-1.51.60.51.51.6
Conditioned locomotion1.01.22.2-1.4-1.41.4-1.41.40.9-1.01.1-1.11.11.4-0.70.7-0.8-1.5-1.0-0.80.5-1.31.2-0.9-1.10.8-1.1-1.40.60.6
Patch foraging indifference point 0 sec0.30.41.10.60.6-0.60.6-0.6-0.80.7-0.60.6-0.6-0.51.0-0.90.60.50.70.6-0.80.6-0.60.70.6-0.70.60.6-0.1-0.1
Patch foraging indifference point AUC0.40.51.1-0.7-0.70.7-0.70.70.9-0.90.5-0.50.50.3-0.91.0-0.7-0.2-0.7-0.81.1-0.60.5-0.8-0.50.9-0.40.3-0.0-0.1
Delay disc. indifference point, 0s delay1.01.14.51.11.1-1.11.1-1.1-0.80.2-1.31.3-1.3-1.10.6-0.50.61.10.60.6-0.60.6-0.60.30.8-0.60.51.9-2.1-2.0
Delay disc. indifference point, 16s delay1.71.73.31.71.7-1.71.7-1.7-1.31.1-1.71.7-1.7-1.11.0-1.01.01.01.01.0-1.00.9-0.80.91.2-1.00.91.0-1.8-1.7
Delay disc. indifference point, 2s delay0.30.43.80.50.5-0.50.5-0.5-0.0-0.3-0.00.0-0.0-0.2-0.30.3-0.20.2-0.2-0.10.3-0.30.2-0.4-0.20.2-0.30.1-1.9-1.9
Delay disc. indifference point, 24s delay1.21.12.11.51.5-1.51.5-1.5-0.91.2-1.31.3-1.3-1.00.6-0.71.01.00.90.9-0.51.1-1.01.11.1-0.81.00.60.30.3
Delay disc. indifference point, 4s delay0.20.21.30.40.4-0.40.4-0.4-0.30.1-0.50.5-0.5-0.30.2-0.20.10.30.20.2-0.20.2-0.20.10.2-0.20.10.5-1.1-1.1
Delay disc. indifference point, 8s delay1.01.02.7-0.6-0.60.6-0.60.61.0-1.20.8-0.80.80.5-1.21.2-1.0-0.5-1.1-1.01.2-1.11.1-1.3-1.01.0-1.10.0-1.6-1.6
Indifference point function ln k0.40.61.20.80.8-0.80.8-0.8-1.01.1-0.70.7-0.7-0.41.0-1.00.80.30.80.8-1.00.7-0.61.00.6-0.80.5-0.40.10.2
Indifference point function log k0.40.61.20.80.8-0.80.8-0.8-1.01.1-0.70.7-0.7-0.41.0-1.00.80.30.80.8-1.00.7-0.61.00.6-0.80.5-0.40.10.2
Patch foraging total patch changes 0 sec0.30.51.20.80.8-0.80.8-0.8-0.90.8-0.70.7-0.7-0.61.1-0.90.70.60.80.7-0.90.7-0.70.80.7-0.80.70.6-0.2-0.1
Patch foraging total patch changes 12 sec0.30.41.50.60.6-0.60.6-0.6-0.50.5-0.70.7-0.7-0.70.6-0.40.60.70.60.5-0.40.5-0.70.50.7-0.50.71.20.00.0
Patch foraging total patch changes 18 sec0.20.21.4-0.3-0.30.3-0.30.30.5-0.70.3-0.30.3-0.1-0.40.6-0.40.2-0.4-0.50.7-0.40.2-0.7-0.20.5-0.21.20.0-0.1
Patch foraging total patch changes 24 sec0.60.71.21.11.1-1.11.1-1.1-0.90.8-1.01.0-1.0-0.90.8-0.70.70.90.80.7-0.60.8-0.80.70.9-0.60.91.1-0.2-0.2
Patch foraging total patch changes 6 sec0.10.11.30.30.3-0.30.3-0.3-0.20.1-0.40.4-0.4-0.50.3-0.20.30.50.30.3-0.20.4-0.40.20.4-0.10.41.1-0.1-0.1
Patch foraging time to switch 0 sec1.11.72.7-1.2-1.21.2-1.21.21.5-1.51.3-1.31.31.2-1.61.6-1.5-1.2-1.5-1.51.6-1.31.3-1.4-1.31.4-1.3-0.7-0.8-0.9
Patch foraging water rate 0 sec0.50.83.8-0.9-0.90.9-0.90.90.8-0.40.9-0.90.91.2-0.60.6-0.7-1.3-0.7-0.80.7-0.60.7-0.4-0.90.7-0.9-2.00.30.3
Patch foraging water rate 12 sec0.81.22.21.21.2-1.21.2-1.2-1.01.5-1.01.0-1.0-0.70.7-0.91.30.71.11.3-0.91.2-1.31.40.9-1.20.9-0.41.41.5
Patch foraging water rate 18 sec0.70.93.9-0.8-0.80.8-0.80.80.8-0.61.1-1.11.11.2-0.70.6-0.8-1.2-0.9-0.80.7-0.91.0-0.7-1.20.8-1.3-2.0-0.7-0.7
Patch foraging water rate 24 sec0.50.73.00.50.5-0.50.5-0.5-0.81.0-0.40.4-0.4-0.40.9-0.91.00.30.80.9-0.90.8-0.71.00.4-0.90.4-0.71.71.7
Patch foraging water rate 6 sec0.10.21.50.40.4-0.40.4-0.4-0.40.7-0.20.2-0.20.10.4-0.40.3-0.10.30.3-0.30.4-0.20.60.1-0.30.0-1.20.40.3
Seeking ratio, delayed vs. immediate footshock1.01.21.81.11.1-1.11.1-1.1-1.11.1-1.01.0-1.0-1.31.2-1.21.01.31.21.0-1.11.2-1.21.11.1-1.11.31.2-0.5-0.5
Distance traveled before self-admin1.81.92.71.31.3-1.31.3-1.3-1.41.6-1.21.2-1.2-1.51.5-1.51.61.41.51.6-1.51.5-1.61.51.3-1.71.21.11.11.1
Distance traveled after self-admin5.15.77.22.62.6-2.62.6-2.6-2.62.5-2.52.5-2.5-2.42.5-2.52.42.42.42.4-2.52.4-2.72.42.3-2.42.31.80.10.2
Extensor digitorum longus weight0.20.71.1-0.9-0.90.9-0.90.90.8-0.90.9-0.90.90.9-0.80.8-0.9-0.9-0.9-0.90.7-1.01.0-0.9-0.90.9-0.8-0.6-0.6-0.6
Bone: elastic displacement0.00.00.1-0.2-0.20.2-0.20.20.2-0.20.2-0.20.20.3-0.20.4-0.2-0.3-0.2-0.20.2-0.20.2-0.2-0.30.2-0.3-0.2-0.1-0.2
Bone: elastic work2.12.73.61.61.6-1.61.6-1.6-1.81.9-1.61.6-1.6-1.51.8-1.71.81.51.81.8-1.71.7-1.81.91.7-1.71.71.01.51.5
Bone: endosteal estimation1.22.53.81.81.8-1.81.8-1.8-1.71.3-1.71.7-1.7-1.81.5-1.51.51.81.61.5-1.51.6-1.51.41.7-1.41.71.9-0.3-0.2
Bone: endosteal perimeter1.12.23.31.81.8-1.81.8-1.8-1.61.3-1.61.6-1.6-1.61.4-1.51.41.61.41.4-1.41.5-1.31.31.5-1.31.51.4-0.5-0.4
Epididymis fat weight0.00.00.4-0.0-0.00.0-0.00.00.2-0.2-0.00.0-0.00.1-0.20.1-0.2-0.1-0.2-0.20.2-0.10.1-0.2-0.00.0-0.00.2-0.6-0.6
Delta time in closed arm before/after self-admin0.80.71.51.01.0-1.01.0-1.0-0.80.8-1.21.2-1.2-0.40.7-0.70.60.40.70.6-0.70.8-0.70.81.0-0.61.00.3-0.9-0.8
Delta time in open arm before/after self-admin0.20.21.9-0.5-0.50.5-0.50.50.2-0.00.5-0.50.50.2-0.00.0-0.1-0.2-0.1-0.10.1-0.00.2-0.1-0.40.1-0.4-0.51.41.3
Diff in mean of infusions in LGA sessions0.10.11.10.30.3-0.30.3-0.3-0.20.1-0.10.1-0.1-0.70.1-0.10.40.80.20.4-0.10.1-0.3-0.00.0-0.4-0.11.0-0.1-0.1
Delay discount exponential model param0.30.32.6-0.7-0.70.7-0.70.70.20.00.5-0.50.50.40.1-0.1-0.1-0.40.0-0.0-0.10.0-0.10.2-0.10.00.1-0.51.61.6
Extinction: sum of active levers before priming1.41.44.11.31.3-1.31.3-1.3-1.20.7-1.21.2-1.2-1.51.1-1.11.01.51.11.0-1.01.2-1.00.81.1-1.01.12.0-0.6-0.5
Active lever presses in extinction session 60.50.51.11.01.0-1.01.0-1.0-0.60.3-0.70.7-0.7-0.80.5-0.40.50.80.50.5-0.30.6-0.60.30.5-0.30.51.0-0.6-0.5
Bone: final force1.72.83.51.61.6-1.61.6-1.6-1.71.8-1.71.7-1.7-1.61.7-1.61.91.61.71.9-1.61.6-1.61.71.7-1.71.71.31.61.6
Bone: final moment2.54.14.91.91.9-1.91.9-1.9-2.12.2-2.02.0-2.0-2.02.2-2.12.21.92.12.2-2.12.0-2.12.12.1-2.02.11.51.81.9
Food consumed during 24 hour testing period0.30.40.80.80.8-0.80.8-0.8-0.70.9-0.60.6-0.6-0.40.7-0.70.60.30.60.6-0.70.6-0.50.80.5-0.70.5-0.30.10.1
Glucose0.30.52.1-0.5-0.50.5-0.50.50.7-0.40.5-0.50.51.1-0.70.8-0.8-1.2-0.7-0.80.8-0.50.6-0.4-0.50.8-0.5-1.5-0.5-0.5
Heart weight0.60.91.40.80.8-0.80.8-0.8-1.01.2-1.01.0-1.0-0.91.0-1.11.00.81.10.9-1.01.0-1.11.11.0-1.01.00.60.90.9
Delay discount hyperbolic model param0.30.33.1-0.6-0.60.6-0.60.60.10.20.4-0.40.40.30.2-0.20.1-0.30.10.1-0.20.1-0.20.30.0-0.10.2-0.41.81.7
Intermittent access intake day 1-15 change1.51.42.61.41.4-1.41.4-1.4-1.01.0-1.51.5-1.5-1.30.8-0.80.91.31.00.9-0.71.2-1.11.01.3-1.01.41.6-0.8-0.7
Intermittent access intake escalation1.11.11.51.21.2-1.21.2-1.2-1.00.8-1.21.2-1.2-1.00.8-0.80.81.00.90.8-0.81.0-0.90.81.2-0.91.21.2-0.9-0.9
Intermittent access intake escalation 23.33.27.51.81.8-1.81.8-1.8-1.71.4-1.91.9-1.9-2.21.6-1.51.72.21.71.7-1.51.9-1.81.52.0-1.82.12.7-0.7-0.6
Intermitt. access day 1 inactive lever presses0.40.51.01.01.0-1.01.0-1.0-0.70.8-0.70.7-0.7-0.20.4-0.50.40.10.50.4-0.40.6-0.40.70.7-0.40.7-0.5-0.9-0.8
Intermitt. access day 15 inactive lever presses0.30.30.70.80.8-0.80.8-0.8-0.50.8-0.50.5-0.50.00.3-0.40.4-0.10.30.4-0.20.3-0.30.60.3-0.30.3-0.9-0.5-0.4
Intermitt. access escalation Index0.20.20.8-0.1-0.10.1-0.10.1-0.50.20.1-0.10.1-0.50.8-0.80.50.50.50.5-0.90.4-0.30.20.2-0.60.30.4-0.0-0.0
Intermittent access day 1 total infusions0.60.74.3-0.8-0.80.8-0.80.8-0.20.40.6-0.60.60.60.6-0.70.4-0.70.30.4-0.9-0.1-0.00.4-0.5-0.4-0.5-1.52.02.1
Intermittent access day 15 total infusions0.80.91.90.70.7-0.70.7-0.7-1.11.2-0.70.7-0.7-0.71.2-1.31.10.71.11.1-1.40.9-1.01.20.7-1.20.70.11.01.0
Intermittent access terminal intake (last 3 days)1.41.52.31.01.0-1.01.0-1.0-1.31.4-1.11.1-1.1-1.11.4-1.41.41.01.41.4-1.51.3-1.31.41.1-1.51.00.61.21.3
Intermittent access total infusions0.70.82.70.40.4-0.40.4-0.4-1.01.1-0.50.5-0.5-0.41.2-1.21.00.31.01.0-1.40.7-0.81.10.4-1.10.4-0.41.61.6
Intermittent access day 1 locomotion0.30.41.3-0.5-0.50.5-0.50.5-0.50.40.3-0.30.30.50.9-1.00.3-0.60.40.3-1.1-0.10.10.4-0.1-0.3-0.1-1.21.01.1
Intermittent access day 15 total locomotion0.10.10.5-0.2-0.20.2-0.20.2-0.00.0-0.00.0-0.00.40.1-0.2-0.0-0.5-0.0-0.0-0.2-0.20.20.10.00.0-0.0-0.5-0.7-0.6
Intermittent access total locomotion0.30.41.4-0.8-0.80.8-0.80.80.3-0.40.5-0.50.51.0-0.10.1-0.5-1.1-0.4-0.5-0.0-0.70.7-0.3-0.50.5-0.5-1.2-0.2-0.2
Intermittent access standard deviation4.64.87.02.52.5-2.52.5-2.5-2.31.9-2.12.1-2.1-2.62.0-2.02.32.62.22.3-2.02.3-2.31.92.1-2.32.22.40.10.3
Left kidney weight2.77.510.12.52.5-2.52.5-2.5-2.83.2-2.92.9-2.9-2.52.9-2.92.72.42.92.7-2.83.0-2.93.13.0-2.73.01.82.42.4
Right kidney weight3.810.612.93.43.4-3.43.4-3.4-3.43.6-3.53.5-3.5-3.33.2-3.23.33.33.43.3-3.23.4-3.43.53.5-3.33.42.61.21.2
Cocaine induced anxiety0.00.10.20.40.4-0.40.4-0.40.0-0.10.0-0.00.0-0.2-0.20.2-0.10.2-0.2-0.10.3-0.10.1-0.2-0.20.1-0.20.4-0.1-0.2
Post-drug Anxiety0.40.51.7-0.1-0.10.1-0.10.10.5-0.80.4-0.40.40.5-0.70.7-0.8-0.4-0.8-0.80.8-0.80.7-0.9-0.70.8-0.8-0.0-1.2-1.3
Baseline Anxiety0.10.10.4-0.7-0.70.7-0.70.70.2-0.20.4-0.40.40.50.1-0.1-0.2-0.5-0.1-0.2-0.1-0.30.1-0.1-0.30.2-0.2-0.50.30.3
Tail length4.814.419.04.44.4-4.44.4-4.4-3.94.0-4.24.2-4.2-3.83.5-3.63.73.83.83.7-3.44.1-3.93.94.1-3.74.12.80.80.9
Length with tail6.925.432.05.75.7-5.75.7-5.7-5.25.6-5.55.5-5.5-5.04.7-4.65.14.85.15.1-4.65.3-5.15.45.4-4.95.43.41.81.9
Length without tail3.27.010.12.92.9-2.92.9-2.9-2.73.2-2.82.8-2.8-2.52.6-2.43.02.42.72.9-2.52.6-2.62.92.7-2.62.71.41.71.7
Times rat made contact with spout0.40.40.8-0.9-0.90.9-0.90.90.8-0.80.6-0.60.60.5-0.70.7-0.5-0.4-0.6-0.50.7-0.50.7-0.7-0.50.6-0.40.10.40.3
Lifetime Intake0.30.32.0-0.3-0.30.3-0.30.3-0.50.50.1-0.10.10.20.7-0.80.5-0.20.50.5-1.00.2-0.30.6-0.1-0.6-0.1-0.81.31.4
Liver weight, left0.10.10.3-0.5-0.50.5-0.50.50.3-0.20.1-0.10.10.3-0.20.1-0.3-0.3-0.2-0.30.2-0.10.4-0.2-0.00.40.00.40.10.1
Liver weight, right0.00.00.40.00.0-0.00.0-0.0-0.00.3-0.10.1-0.10.1-0.0-0.10.2-0.10.10.20.00.1-0.10.30.1-0.20.1-0.10.60.6
Locomotor activity0.40.71.4-0.9-0.90.9-0.90.91.1-1.00.7-0.70.70.6-1.01.2-0.8-0.6-0.8-0.81.2-0.50.5-0.9-0.81.0-0.80.1-0.2-0.3
Locomotor testing distance0.81.42.1-1.2-1.21.2-1.21.21.3-1.41.3-1.31.31.0-1.21.3-1.2-1.0-1.2-1.21.3-1.01.0-1.3-1.41.3-1.5-0.5-0.7-0.8
Locomotor testing rearing1.42.13.6-1.7-1.71.7-1.71.71.7-1.91.5-1.51.50.9-1.61.6-1.5-0.8-1.4-1.51.7-1.11.2-1.7-1.61.6-1.60.5-0.7-0.8
Locomotion in novel chamber0.70.97.5-0.5-0.50.5-0.50.50.6-1.10.4-0.40.40.3-0.60.7-0.8-0.3-0.7-0.80.6-0.60.7-1.0-0.60.7-0.60.5-2.7-2.7
Locomotion in novel chamber post-restriction0.00.00.20.30.3-0.30.3-0.3-0.10.10.2-0.20.2-0.2-0.00.00.10.20.00.10.10.2-0.10.0-0.20.0-0.2-0.4-0.3-0.3
Fecal boli incidents, locomotor time 13.33.76.3-1.7-1.71.7-1.71.71.8-1.81.8-1.81.82.1-1.81.7-2.1-2.2-1.9-2.11.7-1.92.0-1.8-1.82.0-1.8-2.2-2.5-2.5
Change in fecal boli incidents, locomotor task0.30.32.30.20.2-0.20.2-0.2-0.50.0-0.20.2-0.2-0.90.6-0.50.51.00.50.6-0.60.4-0.40.10.4-0.50.51.50.40.4
Time >=10cm from walls, locomotor time 10.00.00.1-0.2-0.20.2-0.20.20.1-0.10.2-0.20.20.2-0.00.0-0.1-0.2-0.1-0.20.1-0.10.1-0.1-0.00.3-0.0-0.2-0.1-0.1
Bouts of movement, locomotor time 10.50.63.50.80.8-0.80.8-0.8-0.60.2-0.30.3-0.3-0.80.5-0.50.30.80.40.2-0.40.3-0.30.10.5-0.10.40.9-1.9-1.9
Total resting periods, locomotor time 10.40.53.70.70.7-0.70.7-0.7-0.50.2-0.10.1-0.1-0.60.5-0.50.20.60.30.1-0.40.3-0.20.00.3-0.00.30.5-1.9-1.9
Rest time, locomotor task time 10.10.10.7-0.2-0.20.2-0.20.20.1-0.10.2-0.20.20.4-0.10.0-0.3-0.4-0.2-0.30.0-0.20.3-0.1-0.20.3-0.1-0.5-0.9-0.8
Distance moved, locomotor task time 10.30.33.00.10.1-0.10.1-0.1-0.20.3-0.40.4-0.4-0.40.2-0.20.50.40.40.5-0.20.5-0.50.40.5-0.60.40.61.71.7
Vertical activity count, locomotor time 11.21.22.80.80.8-0.80.8-0.8-1.00.9-0.80.8-0.8-1.21.0-1.01.21.31.21.2-1.11.3-1.31.01.1-1.21.21.31.61.7
Time >=10cm from walls, locomotor time 20.00.00.3-0.0-0.00.0-0.00.00.00.1-0.20.2-0.2-0.20.1-0.10.20.20.10.10.00.1-0.20.10.30.10.30.50.50.5
Bouts of movement, locomotor time 20.80.99.10.00.0-0.00.0-0.00.3-0.2-0.20.2-0.20.7-0.40.3-0.7-0.7-0.6-0.70.5-0.80.7-0.5-0.30.9-0.6-0.5-3.0-2.9
Total resting periods, locomotor time 20.70.77.1-0.1-0.10.1-0.10.10.4-0.2-0.10.1-0.10.7-0.30.3-0.7-0.7-0.6-0.70.5-0.80.7-0.5-0.40.9-0.6-0.5-2.7-2.6
Rest time, locomotor task time 20.40.43.00.20.2-0.20.2-0.2-0.50.7-0.00.0-0.0-0.40.6-0.60.60.40.60.7-0.60.6-0.60.70.5-0.70.7-0.31.71.7
Distance moved, locomotor task time 20.10.10.7-0.2-0.20.2-0.20.20.2-0.5-0.20.2-0.2-0.0-0.20.2-0.20.1-0.2-0.20.2-0.20.2-0.30.00.3-0.10.8-0.5-0.5
Vertical activity count, locomotor time 20.30.42.00.50.5-0.50.5-0.5-0.3-0.1-0.60.6-0.6-0.70.3-0.20.20.80.30.2-0.20.4-0.40.00.5-0.10.51.4-1.3-1.3
Light reinforcement 10.20.41.6-0.3-0.30.3-0.30.30.7-0.60.4-0.40.40.5-0.81.0-0.8-0.5-0.7-0.81.0-0.50.4-0.6-0.50.6-0.50.0-1.2-1.3
Light reinforcement 26.58.710.9-2.9-2.92.9-2.92.93.0-2.93.1-3.13.13.3-2.72.9-3.1-3.3-3.1-3.12.8-3.13.1-2.9-3.22.9-3.2-3.3-1.6-1.6
Bone: marrow area1.22.63.91.81.8-1.81.8-1.8-1.71.4-1.81.8-1.8-1.81.5-1.61.51.91.61.5-1.61.7-1.51.41.7-1.51.72.0-0.2-0.2
Bone: maximum diameter1.42.53.11.61.6-1.61.6-1.6-1.81.7-1.71.7-1.7-1.51.8-1.71.61.41.71.6-1.71.7-1.51.71.7-1.51.71.11.01.1
Bone: maximum force2.84.95.92.22.2-2.22.2-2.2-2.42.2-2.22.2-2.2-2.32.4-2.32.42.32.32.4-2.32.1-2.12.22.3-2.22.32.11.51.6
Bone: maximum moment3.86.57.72.52.5-2.52.5-2.5-2.82.5-2.62.6-2.6-2.62.8-2.72.72.62.72.7-2.72.5-2.52.52.6-2.52.62.31.71.7
Mean time between licks in bursts0.20.21.10.30.3-0.30.3-0.3-0.40.6-0.40.4-0.4-0.30.5-0.50.60.30.50.6-0.50.3-0.30.50.4-0.50.40.31.11.1
Mean num. licks in bursts0.91.14.91.01.0-1.01.0-1.0-0.90.5-1.11.1-1.1-1.40.7-0.70.91.51.00.9-0.71.2-1.10.71.2-0.81.22.2-0.2-0.1
Cd content in liver0.40.51.0-0.5-0.50.5-0.50.50.6-1.00.7-0.70.70.2-0.70.7-0.6-0.1-0.6-0.60.6-0.70.7-1.0-0.70.6-0.80.4-1.0-1.0
Co content in liver1.72.02.6-1.6-1.61.6-1.61.61.3-1.41.6-1.61.61.5-1.21.3-1.4-1.5-1.4-1.41.0-1.51.5-1.4-1.61.4-1.6-1.4-0.1-0.1
Cu content in liver1.11.32.51.11.1-1.11.1-1.1-1.21.6-1.21.2-1.2-0.81.3-1.11.10.81.21.1-1.31.1-1.21.51.2-1.31.20.11.01.0
Fe content in liver0.40.51.3-0.4-0.40.4-0.40.40.7-0.60.6-0.60.60.8-0.80.8-0.7-0.8-0.8-0.70.9-0.60.7-0.6-0.60.8-0.6-0.9-1.1-1.1
K content in liver0.60.61.20.60.6-0.60.6-0.6-0.81.1-0.80.8-0.8-0.50.9-0.80.70.50.80.7-0.80.8-0.91.00.9-0.90.90.31.11.1
Mg content in liver0.20.22.3-0.1-0.10.1-0.10.1-0.10.6-0.10.1-0.10.20.3-0.20.2-0.30.20.2-0.20.2-0.20.50.2-0.30.2-0.71.51.5
Mn content in liver0.70.84.9-0.0-0.00.0-0.00.0-0.60.8-0.60.6-0.6-0.60.9-0.90.80.60.90.8-0.90.8-0.90.90.7-0.90.80.82.22.1
Na content in liver5.25.56.52.32.3-2.32.3-2.3-2.42.4-2.52.5-2.5-2.32.4-2.52.42.32.42.4-2.32.5-2.52.52.5-2.42.62.11.21.3
Rb content in liver0.00.00.40.10.1-0.10.1-0.10.00.1-0.10.1-0.10.0-0.00.1-0.0-0.1-0.1-0.00.1-0.0-0.00.10.10.00.10.1-0.7-0.6
Se content in liver3.34.06.5-2.5-2.52.5-2.52.52.3-2.02.0-2.02.02.0-2.02.1-1.9-2.0-1.9-1.92.0-1.81.8-1.8-1.91.8-1.8-1.51.00.9
Sr content in liver0.70.71.0-1.0-1.01.0-1.01.00.7-0.70.9-0.90.90.9-0.60.5-0.7-0.9-0.7-0.70.4-0.80.8-0.7-0.90.7-0.9-1.00.80.7
Zn content in liver0.30.41.3-0.6-0.60.6-0.60.60.5-0.40.6-0.60.60.8-0.50.5-0.6-0.8-0.6-0.60.5-0.60.5-0.4-0.70.5-0.7-1.20.30.2
Bone: minimum diameter5.510.215.23.23.2-3.23.2-3.2-3.42.8-3.23.2-3.2-3.73.3-3.33.33.83.43.3-3.43.3-3.32.93.2-3.23.13.91.31.3
Time in familiar zone, hab. session 10.30.30.90.60.6-0.60.6-0.6-0.60.3-0.60.6-0.6-0.60.4-0.40.50.60.50.5-0.60.7-0.50.40.6-0.50.51.0-0.2-0.1
Time in novel zone, hab. session 10.20.20.4-0.5-0.50.5-0.50.50.4-0.20.4-0.40.40.4-0.20.2-0.3-0.4-0.3-0.30.4-0.50.3-0.2-0.40.3-0.4-0.60.40.3
Total zone transitions, hab. session 10.60.94.30.90.9-0.90.9-0.9-0.90.4-0.90.9-0.9-1.20.9-0.80.81.30.80.8-0.70.8-0.90.50.9-0.80.92.1-0.8-0.7
Total locomotion distance, hab. session 13.14.410.72.32.3-2.32.3-2.3-2.11.5-2.22.2-2.2-2.61.9-2.02.02.72.02.0-1.82.0-2.01.62.1-1.92.13.3-1.1-0.9
Locomotion velocity, hab. session 11.42.05.91.61.6-1.61.6-1.6-1.40.9-1.41.4-1.4-1.81.3-1.31.31.91.21.3-1.11.2-1.30.91.3-1.21.32.4-1.2-1.1
Time in familiar zone, hab. session 20.40.40.90.90.9-0.90.9-0.9-0.70.6-0.60.6-0.6-0.70.6-0.50.70.70.60.7-0.50.6-0.50.50.5-0.70.50.3-0.2-0.2
Time in novel zone, hab. session 20.60.60.9-0.9-0.90.9-0.90.90.9-0.80.7-0.70.70.8-0.80.7-0.9-0.7-0.8-0.90.9-0.80.7-0.7-0.70.9-0.7-0.4-0.5-0.5
Total zone transitions, hab. session 20.10.21.3-0.6-0.60.6-0.60.60.4-0.10.3-0.30.30.2-0.10.10.0-0.2-0.20.00.3-0.20.2-0.0-0.2-0.0-0.20.01.11.1
Total locomotion distance, hab. session 20.40.51.20.60.6-0.60.6-0.6-0.60.6-0.60.6-0.6-0.90.7-0.80.90.90.70.9-0.60.6-0.60.60.7-0.90.71.10.70.7
Locomotion velocity, hab. session 20.30.51.10.40.4-0.40.4-0.4-0.50.6-0.60.6-0.6-0.80.7-0.70.90.80.70.9-0.60.6-0.60.60.6-0.80.61.10.90.9
Novel to familiar place preference ratio1.21.23.41.11.1-1.11.1-1.1-0.90.7-1.21.2-1.2-1.40.9-1.00.91.51.00.9-0.71.3-1.30.81.3-1.01.31.9-0.5-0.4
Novelty place preference1.11.12.71.11.1-1.11.1-1.1-0.90.7-1.21.2-1.2-1.30.9-1.00.91.30.90.9-0.61.2-1.30.81.2-0.91.21.6-0.5-0.4
Time in novel zone, NPP test0.70.72.20.80.8-0.80.8-0.8-0.60.5-0.90.9-0.9-1.10.7-0.70.71.10.70.7-0.41.0-1.10.60.9-0.71.01.5-0.4-0.4
Total zone transitions, NPP test0.20.20.8-0.3-0.30.3-0.30.30.5-0.60.3-0.30.30.4-0.50.5-0.4-0.4-0.5-0.40.6-0.40.6-0.5-0.40.4-0.4-0.2-0.9-0.8
Total locomotion distance, NPP test1.72.34.31.71.7-1.71.7-1.7-1.51.1-1.51.5-1.5-1.81.4-1.41.51.91.41.5-1.31.4-1.41.21.4-1.51.42.1-0.6-0.4
Locomotion velocity, NPP test2.12.95.12.02.0-2.02.0-2.0-1.81.3-1.81.8-1.8-2.11.6-1.71.82.11.71.8-1.51.7-1.61.41.7-1.71.62.3-0.5-0.3
Intraocular pressure0.10.10.60.00.0-0.00.0-0.00.2-0.30.1-0.10.10.3-0.30.5-0.3-0.4-0.3-0.30.2-0.20.3-0.2-0.20.6-0.2-0.8-0.7-0.7
Delta distance traveled before/after self-admin0.90.93.01.31.3-1.31.3-1.3-0.90.6-1.11.1-1.1-0.80.6-0.60.50.80.60.5-0.60.6-0.70.50.8-0.40.80.7-1.7-1.6
Delta ambulatory time before/after self-admin1.21.41.91.41.4-1.41.4-1.4-1.30.9-1.41.4-1.4-1.21.2-1.20.91.21.10.9-1.11.0-1.11.01.2-0.91.21.1-0.8-0.7
Parametrial fat weight0.61.11.9-1.3-1.31.3-1.31.31.1-0.71.0-1.01.01.3-0.90.9-1.0-1.3-1.0-1.00.9-1.01.0-0.8-1.01.0-1.0-1.40.80.7
Pavlov. Cond. lever latency0.20.20.5-0.2-0.20.2-0.20.20.4-0.50.4-0.40.40.3-0.40.4-0.5-0.3-0.5-0.50.5-0.50.4-0.5-0.50.4-0.5-0.4-0.7-0.7
Pavlov. Cond. magazine entry latency0.10.10.4-0.3-0.30.3-0.30.30.3-0.20.4-0.40.40.5-0.30.3-0.3-0.5-0.3-0.30.2-0.50.4-0.3-0.50.3-0.5-0.6-0.1-0.1
Pavlov. Cond. change in total contacts0.00.00.10.00.0-0.00.0-0.0-0.10.1-0.00.0-0.00.00.1-0.00.0-0.10.10.0-0.3-0.10.00.10.0-0.00.0-0.20.20.2
Pavlov. Cond. index score0.00.00.4-0.1-0.10.1-0.10.1-0.10.2-0.10.1-0.10.10.1-0.10.1-0.10.20.1-0.30.1-0.00.20.1-0.20.10.00.70.7
Pavlov. Cond. latency score0.10.10.30.00.0-0.00.0-0.0-0.30.3-0.20.2-0.2-0.10.3-0.20.30.00.30.3-0.40.3-0.20.30.2-0.30.20.20.50.5
Pavlov. Cond. lever contacts0.70.81.20.90.9-0.90.9-0.9-1.01.0-1.01.0-1.0-0.70.9-0.91.00.71.01.0-1.11.0-0.91.11.0-0.91.00.80.50.6
Pavlov. Cond. magazine entry number0.00.10.10.30.3-0.30.3-0.3-0.10.2-0.30.3-0.3-0.30.1-0.10.10.30.20.1-0.00.3-0.20.20.3-0.10.30.3-0.2-0.2
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.6-0.60.6-0.60.60.4-0.40.4-0.40.40.2-0.30.3-0.4-0.2-0.3-0.40.3-0.40.2-0.4-0.30.3-0.30.10.60.6
Pavlov. Cond. lever-magazine prob. diff.0.10.21.1-0.0-0.00.0-0.00.0-0.30.4-0.20.2-0.2-0.10.4-0.30.40.10.40.4-0.60.3-0.30.40.3-0.40.30.11.01.0
Pavlov. Cond. response bias0.10.10.20.20.2-0.20.2-0.2-0.40.4-0.30.3-0.3-0.20.4-0.30.40.20.40.4-0.50.3-0.30.40.3-0.40.30.20.30.4
Pavlov. Cond. lever latency3.14.25.7-2.4-2.42.4-2.42.42.3-2.12.0-2.02.02.1-2.22.2-2.1-2.0-2.1-2.12.1-2.12.2-2.0-1.92.0-1.9-1.5-0.0-0.1
Pavlov. Cond. magazine entry latency1.61.92.91.71.7-1.71.7-1.7-1.61.7-1.51.5-1.5-1.11.5-1.41.31.01.31.3-1.41.3-1.41.61.4-1.31.30.2-0.00.0
Pavlov. Cond. change in total contacts5.98.210.73.33.3-3.33.3-3.3-3.22.9-2.92.9-2.9-3.03.0-3.03.03.02.93.0-3.02.8-3.02.82.7-2.92.62.50.20.3
Pavlov. Cond. index score2.83.65.42.32.3-2.32.3-2.3-2.22.0-1.91.9-1.9-1.82.0-2.01.91.71.91.9-1.91.8-2.01.91.8-1.81.71.1-0.3-0.2
Pavlov. Cond. latency score2.73.35.02.22.2-2.22.2-2.2-2.12.0-1.91.9-1.9-1.61.9-1.91.81.61.81.8-1.81.8-1.91.91.7-1.81.60.9-0.2-0.1
Pavlov. Cond. lever contacts2.94.05.52.32.3-2.32.3-2.3-2.32.0-2.02.0-2.0-2.02.2-2.22.02.02.02.0-2.12.0-2.12.01.9-2.01.81.5-0.1-0.0
Pavlov. Cond. magazine entry number1.21.42.7-1.7-1.71.7-1.71.71.4-1.31.2-1.21.20.9-1.11.1-1.0-0.9-1.0-1.01.1-1.01.1-1.1-1.11.0-1.0-0.30.90.8
Pavlov. Cond. intertrial magazine entries1.01.32.3-1.3-1.31.3-1.31.31.2-0.71.2-1.21.21.3-1.11.1-0.9-1.3-1.0-0.91.1-1.01.0-0.8-1.10.9-1.1-1.51.01.0
Pavlov. Cond. lever-magazine prob. diff.3.24.05.82.42.4-2.42.4-2.4-2.32.2-2.12.1-2.1-1.92.2-2.12.01.82.02.0-2.12.0-2.12.11.9-2.01.91.3-0.2-0.1
Pavlov. Cond. response bias3.34.56.22.52.5-2.52.5-2.5-2.42.2-2.12.1-2.1-2.12.3-2.32.22.12.22.2-2.22.1-2.22.12.0-2.12.01.5-0.00.1
Time in closed arm before self-admin0.40.42.1-0.8-0.80.8-0.80.80.3-0.10.9-0.90.90.2-0.20.20.1-0.2-0.10.10.0-0.40.2-0.2-0.6-0.0-0.5-0.41.41.4
Time in closed arm after self-admin0.20.20.50.30.3-0.30.3-0.3-0.60.6-0.30.3-0.3-0.10.5-0.60.50.10.40.5-0.70.1-0.40.50.3-0.60.3-0.2-0.5-0.4
Time in open arm before self-admin1.31.42.21.41.4-1.41.4-1.4-1.21.1-1.51.5-1.5-1.11.0-1.01.11.11.11.1-0.91.3-1.21.21.4-1.01.30.90.30.4
Time in open arm after self-admin1.01.13.30.70.7-0.70.7-0.7-0.80.9-0.90.9-0.9-1.11.0-1.01.01.11.11.0-0.81.4-1.01.01.1-0.71.21.01.81.8
Bone: periosteal estimation2.04.25.22.12.1-2.12.1-2.1-2.21.9-2.12.1-2.1-2.32.1-2.12.12.32.12.1-2.12.2-2.01.92.1-1.92.12.30.80.8
Bone: periosteal perimeter1.72.93.71.91.9-1.91.9-1.9-1.81.6-1.81.8-1.8-1.91.7-1.81.71.91.71.7-1.71.7-1.61.61.8-1.51.71.80.10.1
Bone: post-yield work0.81.01.51.21.2-1.21.2-1.2-1.10.8-1.01.0-1.0-1.21.0-1.11.01.20.91.0-0.90.8-0.80.71.0-1.00.91.2-0.6-0.6
Progressive ratio test 1 active lever presses1.71.84.90.70.7-0.70.7-0.7-1.61.6-0.80.8-0.8-0.92.0-2.01.60.81.71.6-2.21.3-1.41.71.1-1.71.1-0.11.31.5
Progressive ratio test 1 breakpoint2.02.14.70.90.9-0.90.9-0.9-1.71.9-1.11.1-1.1-1.12.0-2.11.71.01.81.7-2.21.5-1.61.91.3-1.71.30.21.01.2
Progressive ratio test 1 inactive lever presses0.40.41.10.80.8-0.80.8-0.8-0.90.8-0.30.3-0.3-0.21.0-1.00.50.20.70.5-1.00.6-0.40.80.4-0.60.4-0.60.30.4
Progressive ratio test 2 active lever presses0.60.71.80.70.7-0.70.7-0.7-1.11.1-0.70.7-0.7-0.41.2-1.30.90.31.00.9-1.30.7-0.81.10.7-0.90.6-0.30.20.3
Progressive ratio test 2 breakpoint0.60.71.90.70.7-0.70.7-0.7-1.11.2-0.70.7-0.7-0.41.3-1.30.90.31.00.9-1.40.8-0.81.20.7-1.00.6-0.50.30.4
Progressive ratio test 2 inactive lever presses2.52.94.02.02.0-2.02.0-2.0-2.02.0-1.71.7-1.7-1.51.9-2.01.71.41.81.7-2.01.7-1.61.91.6-1.81.60.5-0.2-0.1
Incentive Sensitization - Responses0.10.10.40.30.3-0.30.3-0.3-0.00.2-0.20.2-0.20.2-0.0-0.0-0.2-0.3-0.1-0.20.1-0.10.10.10.00.2-0.1-0.4-0.6-0.6
Incentive Sensitization - Breakpoint0.10.10.50.10.1-0.10.1-0.10.2-0.0-0.10.1-0.10.4-0.30.2-0.4-0.4-0.3-0.40.4-0.30.3-0.2-0.20.4-0.3-0.5-0.7-0.7
Sum of active levers in priming session hrs 5-60.20.23.6-0.0-0.00.0-0.00.00.0-0.4-0.20.2-0.2-0.80.10.00.20.90.10.20.10.1-0.2-0.30.2-0.00.21.90.10.1
Progressive ratio0.40.51.0-0.3-0.30.3-0.30.30.6-1.00.6-0.60.60.4-0.80.9-0.7-0.4-0.8-0.70.8-0.71.0-1.0-0.70.8-0.80.2-1.0-1.0
Food seeking constrained by brief footshock2.83.54.82.02.0-2.02.0-2.0-2.11.7-1.61.6-1.6-2.22.0-2.02.02.21.92.0-2.11.8-2.01.71.7-2.01.72.00.00.1
Seeking ratio, punishment vs. effort1.72.13.31.21.2-1.21.2-1.2-1.61.8-1.21.2-1.2-1.41.8-1.81.61.31.61.6-1.81.5-1.81.81.3-1.71.50.41.21.2
Retroperitoneal fat weight1.03.24.5-2.0-2.02.0-2.02.02.1-1.61.7-1.71.72.0-2.12.0-1.9-2.0-1.8-1.92.1-1.61.5-1.6-1.62.0-1.6-1.50.0-0.1
Reaction time number correct0.10.22.2-0.2-0.20.2-0.20.2-0.10.3-0.10.1-0.1-0.10.3-0.40.30.10.30.3-0.40.3-0.30.40.2-0.40.20.01.51.4
Reaction time mean minus median0.20.20.50.40.4-0.40.4-0.4-0.40.7-0.40.4-0.4-0.30.4-0.40.60.30.50.7-0.40.3-0.50.70.4-0.60.4-0.10.40.5
Reaction time mean minus median AUC0.30.31.00.50.5-0.50.5-0.5-0.61.0-0.60.6-0.6-0.30.6-0.60.60.30.60.7-0.60.4-0.60.90.5-0.60.5-0.20.50.6
Reaction time num false alarms0.71.01.7-1.3-1.31.3-1.31.30.9-1.21.0-1.01.01.1-0.30.5-1.1-1.1-0.9-1.00.5-1.11.2-1.1-1.01.1-1.0-0.6-0.5-0.5
Reaction time num false alarms AUC1.11.52.3-1.5-1.51.5-1.51.51.1-1.41.2-1.21.21.3-0.60.7-1.3-1.3-1.1-1.20.7-1.31.4-1.3-1.21.3-1.2-0.8-0.5-0.6
Reaction time trials correct on left0.10.22.2-0.2-0.20.2-0.20.2-0.10.3-0.10.1-0.1-0.10.3-0.40.30.10.30.3-0.40.3-0.30.40.2-0.40.20.01.51.4
Reaction time trials on left0.10.22.1-0.2-0.20.2-0.20.2-0.10.3-0.10.1-0.1-0.00.3-0.40.30.00.30.3-0.40.3-0.30.40.2-0.30.2-0.01.51.4
Reaction time mean0.10.10.8-0.3-0.30.3-0.30.30.2-0.00.3-0.30.30.5-0.20.2-0.2-0.5-0.2-0.10.0-0.40.3-0.1-0.3-0.0-0.3-0.9-0.00.0
Reaction time mean AUC0.20.31.6-0.6-0.60.6-0.60.60.4-0.10.5-0.50.50.8-0.30.3-0.3-0.8-0.4-0.30.2-0.60.5-0.2-0.50.2-0.5-1.30.10.1
Median of all reaction times0.20.21.0-0.5-0.50.5-0.50.50.4-0.40.5-0.50.50.7-0.30.3-0.4-0.7-0.4-0.40.2-0.60.5-0.3-0.50.2-0.5-1.0-0.2-0.2
Reaction time omissions0.20.30.6-0.8-0.80.8-0.80.80.4-0.40.6-0.60.60.6-0.20.2-0.3-0.6-0.3-0.30.0-0.40.6-0.3-0.50.3-0.5-0.60.30.3
Reaction time false alarm rate1.01.42.1-1.2-1.21.2-1.21.21.0-1.41.1-1.11.11.2-0.70.9-1.3-1.2-1.2-1.30.9-1.41.4-1.3-1.21.4-1.2-0.9-1.3-1.3
Reaction time premature initiation rate0.00.00.10.20.2-0.20.2-0.2-0.1-0.0-0.00.0-0.0-0.2-0.10.00.10.2-0.00.10.1-0.0-0.0-0.1-0.10.1-0.10.2-0.2-0.2
Reaction time premature initiations0.00.00.50.10.1-0.10.1-0.1-0.10.1-0.00.0-0.0-0.2-0.0-0.10.20.20.10.2-0.10.1-0.10.1-0.0-0.1-0.10.20.70.7
Std. dev. reaction times0.10.10.50.20.2-0.20.2-0.2-0.30.7-0.20.2-0.2-0.10.3-0.30.50.00.40.6-0.40.1-0.30.60.2-0.50.2-0.50.70.7
Reaction time trials completed0.10.22.1-0.2-0.20.2-0.20.2-0.10.3-0.10.1-0.1-0.00.3-0.40.30.00.30.3-0.40.3-0.30.40.2-0.30.2-0.01.51.4
Reaction time trials AUC0.20.32.9-0.4-0.40.4-0.40.40.00.20.1-0.10.10.10.2-0.30.2-0.10.20.2-0.30.2-0.20.30.0-0.30.1-0.21.71.6
Run reversals in cocaine runway, females0.40.42.5-0.4-0.40.4-0.40.40.5-0.20.5-0.50.51.0-0.60.5-0.6-1.0-0.6-0.60.5-0.60.6-0.3-0.50.6-0.5-1.6-0.9-0.8
Run reversals in cocaine runway, males1.11.11.9-1.4-1.41.4-1.41.41.1-0.91.2-1.21.20.9-0.90.9-0.8-0.9-0.9-0.80.9-0.80.8-0.8-1.10.8-1.0-1.00.70.6
Latency to leave start box in cocaine runway0.10.10.4-0.1-0.10.1-0.10.10.4-0.2-0.10.1-0.10.2-0.50.5-0.3-0.2-0.4-0.30.7-0.30.3-0.2-0.10.3-0.2-0.10.20.1
Latency to leave start box in cocaine runway, F0.40.51.1-0.7-0.70.7-0.70.70.9-0.70.3-0.30.30.6-0.90.9-0.7-0.5-0.8-0.71.1-0.80.8-0.8-0.60.7-0.7-0.3-0.2-0.3
Latency to leave start box in cocaine runway, M0.10.10.10.30.3-0.30.3-0.3-0.20.3-0.10.1-0.1-0.10.2-0.20.20.10.20.2-0.20.2-0.20.30.3-0.20.4-0.30.30.3
Std. dev. time between licks in bursts0.60.81.80.90.9-0.90.9-0.9-0.90.7-1.01.0-1.0-1.00.8-0.80.81.10.80.8-0.80.8-0.60.70.9-0.80.91.4-0.2-0.1
Total sessions with >9 infusions0.40.53.0-0.9-0.90.9-0.90.9-0.1-0.00.4-0.40.40.30.6-0.60.2-0.30.20.2-0.8-0.10.00.2-0.2-0.3-0.2-0.21.71.7
Short access day 1 total inactive lever presses0.40.40.90.90.9-0.90.9-0.9-0.80.9-0.60.6-0.6-0.50.7-0.80.60.40.60.6-0.70.6-0.50.70.5-0.60.5-0.1-0.3-0.3
Short access day 10 total inactive lever presses0.40.41.11.11.1-1.11.1-1.1-0.70.5-0.50.5-0.5-0.30.4-0.40.40.20.40.4-0.50.3-0.30.50.4-0.50.4-0.2-0.7-0.7
Short access day 1 total infusions0.30.41.10.00.0-0.00.0-0.0-0.60.8-0.20.2-0.2-0.30.9-1.00.70.30.80.7-1.00.7-0.60.80.3-0.80.3-0.21.01.0
Short access day 10 total infusions0.40.42.2-0.7-0.70.7-0.70.70.0-0.10.7-0.70.70.60.2-0.20.0-0.6-0.10.0-0.4-0.40.2-0.1-0.7-0.1-0.7-1.01.51.5
Short access total infusions0.30.41.0-0.9-0.90.9-0.90.90.1-0.00.6-0.60.60.70.3-0.3-0.1-0.7-0.1-0.1-0.5-0.30.3-0.0-0.60.1-0.6-1.00.90.9
Short access day 1 locomotion1.21.32.0-1.4-1.41.4-1.41.41.1-1.11.1-1.11.11.3-0.80.8-1.3-1.2-1.1-1.30.9-1.11.2-1.1-1.11.2-1.0-0.6-0.1-0.1
Short access day 10 total locomotion0.50.62.00.60.6-0.60.6-0.6-1.10.7-0.80.8-0.8-0.41.2-1.20.70.40.80.7-1.40.5-0.40.70.8-0.70.80.4-0.2-0.1
Short access total locomotion0.20.20.4-0.6-0.60.6-0.60.6-0.1-0.20.2-0.20.20.60.5-0.5-0.3-0.6-0.1-0.3-0.6-0.40.5-0.1-0.20.3-0.2-0.30.00.1
One hour access (0.3 mA shock)1.41.62.91.41.4-1.41.4-1.4-1.61.2-1.31.3-1.3-1.11.5-1.51.41.11.31.4-1.71.1-1.21.21.1-1.51.00.9-0.10.0
Compulsive drug intake0.40.41.20.70.7-0.70.7-0.7-0.60.2-0.40.4-0.4-0.90.5-0.50.50.90.50.5-0.50.6-0.50.30.5-0.50.61.1-0.0-0.0
One hour access (shock baseline)0.20.20.60.40.4-0.40.4-0.4-0.60.6-0.40.4-0.4-0.10.6-0.60.60.10.50.6-0.80.4-0.40.60.4-0.60.3-0.20.20.3
Social response proportion4.44.76.51.91.9-1.91.9-1.9-2.32.4-2.02.0-2.0-2.12.2-2.22.62.12.42.6-2.52.3-2.32.42.1-2.52.11.52.02.1
Social responses0.10.10.30.40.4-0.40.4-0.4-0.30.4-0.30.3-0.3-0.10.0-0.10.20.10.20.3-0.20.4-0.30.40.2-0.20.2-0.2-0.5-0.5
Social time0.60.82.81.21.2-1.21.2-1.2-0.60.5-0.80.8-0.8-1.00.1-0.20.51.00.50.5-0.20.8-0.80.40.6-0.50.50.9-1.7-1.7
Soleus weight0.82.43.9-1.4-1.41.4-1.41.41.6-2.01.5-1.51.51.1-1.81.8-1.5-1.0-1.7-1.51.6-1.71.7-2.0-1.61.6-1.6-0.1-1.8-1.8
Bone: stiffness1.52.43.01.51.5-1.51.5-1.5-1.61.3-1.51.5-1.5-1.71.7-1.61.71.71.61.7-1.61.4-1.41.41.5-1.61.51.71.11.2
Tibialis anterior weight0.00.11.3-0.1-0.10.1-0.10.10.0-0.3-0.00.0-0.0-0.30.1-0.0-0.00.40.0-0.0-0.00.0-0.0-0.20.1-0.00.11.2-0.7-0.7
Time to tail flick, vehicle, before self-admin0.30.43.20.00.0-0.00.0-0.0-0.30.6-0.50.5-0.50.10.4-0.50.4-0.20.40.4-0.50.4-0.20.60.4-0.40.40.01.81.8
Time to tail flick, vehicle, after self-admin0.20.20.50.40.4-0.40.4-0.4-0.50.60.1-0.10.1-0.20.5-0.50.60.20.40.6-0.60.4-0.50.60.2-0.40.3-0.60.70.7
Time to tail flick, test, before self-admin0.10.10.3-0.2-0.20.2-0.20.2-0.00.1-0.50.5-0.5-0.10.2-0.20.30.10.20.3-0.10.1-0.20.20.40.00.40.60.30.4
Time to tail flick, test, after self-admin0.10.10.7-0.1-0.10.1-0.10.1-0.20.2-0.10.1-0.10.20.3-0.30.1-0.20.20.1-0.4-0.0-0.00.20.1-0.20.1-0.00.80.8
Delta time to tail flick, vehicle, before/after SA0.10.10.20.30.3-0.30.3-0.3-0.40.30.1-0.10.1-0.40.3-0.30.30.40.30.3-0.40.3-0.40.30.2-0.30.3-0.2-0.3-0.3
Delta time to tail flick, test, before/after SA0.20.22.1-0.1-0.10.1-0.10.1-0.00.10.3-0.30.30.20.1-0.1-0.1-0.20.0-0.1-0.1-0.00.00.1-0.3-0.2-0.2-0.61.41.3
Tibia length1.95.47.12.42.4-2.42.4-2.4-2.62.7-2.42.4-2.4-2.12.6-2.52.52.12.52.5-2.52.5-2.52.62.4-2.32.41.51.21.3
Ambulatory time before self-admin1.01.01.60.90.9-0.90.9-0.9-1.01.1-0.80.8-0.8-1.11.1-1.11.21.11.11.2-1.01.1-1.21.10.8-1.30.80.90.70.7
Ambulatory time after self-admin5.35.87.42.72.7-2.72.7-2.7-2.62.5-2.52.5-2.5-2.52.5-2.52.52.52.42.5-2.42.4-2.62.42.3-2.52.31.70.40.5
Bone: tissue strength4.34.25.22.12.1-2.12.1-2.1-2.32.0-2.12.1-2.1-2.12.2-2.22.12.12.22.1-2.32.1-2.12.02.1-2.12.11.51.01.1
Total heroin consumption1.61.98.01.41.4-1.41.4-1.4-1.30.8-1.31.3-1.3-2.11.3-1.21.32.21.31.3-1.11.3-1.50.81.2-1.31.22.8-0.1-0.2
Bone: trabecular number0.10.10.30.40.4-0.40.4-0.4-0.40.4-0.40.4-0.4-0.20.4-0.20.30.10.40.3-0.50.4-0.20.40.5-0.20.50.20.20.2
Bone: trabecular spacing1.72.13.01.51.5-1.51.5-1.5-1.51.3-1.51.5-1.5-1.71.5-1.61.61.71.51.6-1.31.5-1.61.31.5-1.61.41.70.40.4
Bone: trabecular thickness0.30.41.4-0.6-0.60.6-0.60.60.5-0.10.4-0.40.40.8-0.40.4-0.5-0.9-0.4-0.50.3-0.30.5-0.1-0.40.6-0.4-1.20.90.9
Bone: trabecular tissue density2.43.44.2-1.9-1.91.9-1.91.92.0-2.01.9-1.91.91.8-2.02.0-2.0-1.7-1.9-2.02.0-1.81.8-1.9-1.92.0-1.9-1.3-0.6-0.7
Water consumed over 24 hours0.81.01.90.70.7-0.70.7-0.7-0.91.2-1.01.0-1.0-0.71.0-1.01.10.71.01.1-1.01.1-0.81.21.1-1.11.20.31.41.4
Number of responses in last shaping day2.02.13.11.11.1-1.11.1-1.1-1.41.7-1.31.3-1.3-1.51.5-1.51.71.51.61.7-1.41.8-1.61.71.6-1.61.71.01.31.4