Hub : Genes

MAST1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression MAST1 0.22 0.09 0.0e+00 0.24 0.22 0.23 0.24 5.4e-22 8.4e-20 2.3e-21 6.1e-22
2 NAcc mRNA stability MAST1 0.03 0.02 3.6e-03 0.02 0.01 0.01 0.01 2.2e-03 7.8e-03 1.1e-02 1.4e-02
3 PL gene expression MAST1 0.12 0.05 4.7e-12 0.09 0.11 0.11 0.11 4.7e-10 8.5e-12 2.2e-12 1.2e-11
4 BLA gene expression MAST1 0.14 0.08 9.5e-05 0.05 0.05 0.05 0.05 1.5e-03 1.3e-03 8.3e-04 1.3e-03
5 NAcc gene expression MAST1 0.1 0.05 1.1e-09 0.06 0.07 0.07 0.07 3.6e-07 2.7e-08 1.3e-08 4.3e-08
6 OFC gene expression MAST1 0.38 0.14 4.0e-06 0.19 0.1 0.07 0.15 2.4e-05 2.6e-03 9.3e-03 2.5e-04
7 Brain mRNA stability MAST1 0.08 0.04 8.7e-07 0.07 0.07 0.07 0.07 2.0e-07 4.8e-07 2.1e-07 2.8e-07
8 PL mRNA stability MAST1 0.06 0.03 2.4e-06 0.05 0.04 0.04 0.04 2.4e-06 9.8e-06 1.0e-05 1.2e-05
9 IL gene expression MAST1 0.19 0.1 1.6e-03 0.07 0.07 0.02 0.06 8.6e-03 9.2e-03 1.2e-01 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density3.66.08.0-2.72.7-2.8-2.0-2.8-2.22.22.2-2.1
Area under the delay curve0.00.10.20.4-0.40.00.00.0-0.30.20.00.1
BMI with tail1.75.76.82.6-2.62.51.22.62.4-2.4-2.52.2
BMI without tail0.20.30.60.8-0.80.60.50.60.4-0.4-0.40.5
Body weight0.31.11.90.7-0.70.7-0.21.01.3-1.3-1.41.3
Weight adjusted by age0.50.61.10.8-0.80.81.10.80.6-0.6-0.60.5
Bone surface3.76.68.5-2.32.3-2.7-1.1-2.8-2.92.92.8-2.8
Bone volume4.16.98.3-2.62.6-2.8-1.3-2.9-2.82.82.8-2.7
Breakpoint value in progressive ratio session3.23.57.00.3-0.31.0-0.91.52.6-2.5-2.72.6
Number of licking bursts0.20.31.0-0.60.6-0.5-1.0-0.30.2-0.2-0.40.3
Context. condit. distance diff. score1.92.32.91.7-1.71.70.81.71.5-1.5-1.51.5
Locomotion velocity, session 11.61.72.5-1.61.6-1.4-1.3-1.5-1.01.01.0-1.0
Locomotion distance, session 10.30.31.5-0.60.6-0.5-1.2-0.30.3-0.3-0.40.5
Locomotion velocity, session 20.70.81.6-1.11.1-1.0-1.3-1.0-0.50.50.5-0.5
Locomotion distance, session 20.50.71.50.1-0.10.3-0.90.51.0-1.0-1.21.2
Locomotion velocity, session 30.10.10.50.1-0.10.00.4-0.1-0.40.40.7-0.4
Locomotion distance, session 31.41.53.4-0.50.5-0.9-0.2-1.1-1.61.61.8-1.6
Stereotopy head waving bouts, day 30.70.92.60.9-0.90.51.60.2-0.90.90.9-0.9
Stereotopy head waving duration, day 30.30.41.30.9-0.90.61.20.5-0.10.10.1-0.2
Locomotion velocity, session 70.10.20.30.6-0.60.50.40.40.2-0.2-0.30.2
Locomotion distance, session 70.10.20.7-0.50.5-0.2-0.8-0.20.2-0.2-0.20.1
Stereotopy head waving bouts, day 71.31.42.9-0.40.4-0.90.3-1.0-1.61.61.7-1.6
Stereotopy head waving duration, day 71.31.63.0-0.60.6-1.10.1-1.2-1.61.61.7-1.7
Locomotion velocity, session 80.20.20.6-0.20.20.1-0.80.10.5-0.5-0.50.5
Locomotion distance, session 80.91.32.30.7-0.70.9-0.61.01.4-1.4-1.41.5
Degree of sensitization distance1.11.12.70.0-0.00.6-0.50.81.5-1.5-1.61.4
Degree of sensitization stereotypy0.40.40.9-0.00.0-0.30.4-0.5-0.90.91.0-0.8
Conditioned locomotion0.00.00.0-0.20.2-0.2-0.1-0.1-0.00.00.10.1
Cocaine response after cond. corrected1.21.42.30.7-0.71.0-0.11.21.5-1.5-1.31.5
Cocaine response after cond. not corrected1.41.52.80.6-0.60.9-0.31.21.7-1.7-1.51.7
Cocaine response before conditioning0.40.50.6-0.70.7-0.8-0.6-0.8-0.60.60.7-0.7
Saline control response1.21.65.8-1.71.7-1.3-2.4-0.90.4-0.4-0.40.5
Bone: connectivity density6.09.412.0-3.23.2-3.4-2.4-3.5-3.03.02.9-2.8
Bone: cortical apparent density0.20.30.70.8-0.80.60.70.40.0-0.00.1-0.1
Bone: cortical area0.00.10.5-0.10.1-0.2-0.7-0.10.1-0.1-0.20.1
Bone: cortical porosity1.01.11.50.9-0.91.10.71.11.1-1.1-1.21.2
Bone: cortical porosity0.60.60.80.8-0.80.90.70.90.7-0.7-0.70.9
Bone: cortical thickness1.62.73.21.7-1.71.70.61.81.7-1.7-1.71.8
Bone: cortical thickness2.52.95.80.2-0.20.8-1.41.12.4-2.4-2.32.3
Bone: cortical tissue density0.20.20.50.7-0.70.40.60.2-0.20.20.3-0.3
Condit. Reinf. active minus inactive responses0.60.71.91.4-1.41.00.90.6-0.20.20.1-0.0
Condit. Reinf. active-inactive response ratio1.21.32.21.5-1.51.40.51.20.9-0.9-1.01.1
Condit. Reinf. active responses0.30.40.70.6-0.60.20.6-0.1-0.80.80.6-0.6
Condit. Reinf. inactive responses2.83.34.2-1.81.8-1.9-0.8-2.0-2.02.01.9-1.9
Incentive salience index mean0.91.02.40.1-0.1-0.40.2-0.8-1.51.51.3-1.4
Condit. Reinf. lever presses2.63.56.1-1.11.1-1.6-0.3-1.9-2.52.52.2-2.4
Condit. Reinf. active minus inactive responses0.20.30.6-0.30.3-0.40.1-0.5-0.70.70.7-0.5
Condit. Reinf. active-inactive response ratio0.10.10.20.3-0.30.40.50.40.2-0.2-0.20.4
Condit. Reinf. active responses0.10.10.2-0.50.5-0.3-0.4-0.3-0.20.20.30.0
Condit. Reinf. inactive responses0.20.30.5-0.10.10.1-0.50.30.7-0.7-0.70.7
Condit. Reinf. lever presses0.10.10.20.2-0.20.20.40.30.3-0.3-0.20.5
Condit. Reinf. lever reinforcers received0.10.10.2-0.40.4-0.3-0.2-0.3-0.20.20.3-0.0
Conditioned reinforcement - actives0.10.10.30.3-0.30.30.60.40.3-0.3-0.30.1
Conditioned reinforcement - inactives0.10.10.20.4-0.40.50.50.30.1-0.1-0.1-0.1
Conditioned locomotion0.00.00.20.2-0.20.20.40.1-0.20.20.1-0.2
Patch foraging indifference point 0 sec0.10.10.40.3-0.30.10.1-0.1-0.60.60.6-0.2
Patch foraging indifference point AUC1.41.63.4-1.81.8-1.4-1.7-1.3-0.50.40.5-0.4
Delay disc. indifference point, 0s delay1.11.21.7-1.21.2-1.3-0.9-1.2-1.01.01.0-1.2
Delay disc. indifference point, 16s delay1.31.32.21.0-1.01.00.31.21.2-1.2-1.41.5
Delay disc. indifference point, 2s delay0.40.51.21.1-1.10.80.70.70.0-0.2-0.10.2
Delay disc. indifference point, 24s delay0.40.41.01.0-1.00.80.60.70.3-0.3-0.30.4
Delay disc. indifference point, 4s delay1.01.01.7-0.60.6-1.1-0.6-1.1-1.31.31.2-1.1
Delay disc. indifference point, 8s delay0.10.10.10.4-0.40.10.20.0-0.30.30.00.0
Indifference point function ln k1.21.74.61.9-1.91.42.11.1-0.00.10.1-0.0
Indifference point function log k1.21.74.61.9-1.91.42.11.1-0.00.10.1-0.0
Patch foraging total patch changes 0 sec0.10.20.40.7-0.70.50.30.3-0.20.20.20.2
Patch foraging total patch changes 12 sec0.70.92.7-1.21.2-1.1-1.6-1.0-0.50.40.5-0.2
Patch foraging total patch changes 18 sec2.53.36.0-2.42.4-2.1-2.4-1.9-1.11.01.0-0.8
Patch foraging total patch changes 24 sec1.31.62.3-1.41.4-1.4-1.5-1.5-1.11.11.1-0.9
Patch foraging total patch changes 6 sec0.40.51.4-1.01.0-0.8-1.2-0.8-0.30.30.3-0.1
Patch foraging time to switch 0 sec0.10.10.5-0.10.1-0.2-0.70.00.2-0.3-0.40.2
Patch foraging water rate 0 sec0.00.00.1-0.10.10.20.30.10.2-0.2-0.10.2
Patch foraging water rate 12 sec0.20.30.70.4-0.40.30.8-0.1-0.60.60.7-0.7
Patch foraging water rate 18 sec1.41.93.9-0.00.0-0.51.3-1.0-2.01.91.9-1.7
Patch foraging water rate 24 sec0.50.71.30.7-0.70.21.2-0.1-1.00.90.9-1.0
Patch foraging water rate 6 sec2.84.16.9-2.62.6-2.3-1.9-2.3-1.41.41.5-1.5
Seeking ratio, delayed vs. immediate footshock0.91.01.81.3-1.31.21.11.20.7-0.7-0.60.5
Distance traveled before self-admin0.70.71.10.9-0.91.00.71.00.8-0.8-0.90.6
Distance traveled after self-admin0.60.71.30.9-0.91.01.10.90.6-0.7-0.70.3
Extensor digitorum longus weight0.41.42.40.7-0.71.0-0.11.21.5-1.5-1.51.6
Bone: elastic displacement0.50.61.61.1-1.11.01.30.70.2-0.2-0.10.2
Bone: elastic work1.72.23.01.7-1.71.71.31.61.3-1.3-1.21.4
Bone: endosteal estimation0.30.62.1-1.11.1-0.9-1.5-0.70.0-0.00.0-0.1
Bone: endosteal perimeter0.71.32.0-1.31.3-1.4-1.4-1.3-1.01.00.8-0.8
Epididymis fat weight0.20.50.9-0.10.10.1-1.00.40.9-0.8-0.90.9
Delta time in closed arm before/after self-admin0.60.51.11.1-1.10.91.00.70.3-0.3-0.20.3
Delta time in open arm before/after self-admin1.91.85.1-1.91.9-1.5-2.3-1.00.3-0.3-0.40.5
Diff in mean of infusions in LGA sessions0.10.10.3-0.60.6-0.5-0.3-0.30.1-0.1-0.20.1
Delay discount exponential model param0.10.10.2-0.50.5-0.0-0.0-0.00.3-0.3-0.1-0.1
Extinction: sum of active levers before priming0.80.81.81.3-1.31.11.00.90.3-0.3-0.40.3
Active lever presses in extinction session 60.40.40.80.3-0.30.00.6-0.2-0.90.90.8-0.8
Bone: final force0.10.20.7-0.30.3-0.1-0.80.10.5-0.5-0.50.6
Bone: final moment0.10.20.6-0.10.10.1-0.80.20.6-0.6-0.60.6
Food consumed during 24 hour testing period4.75.712.2-3.33.3-2.9-3.5-2.5-0.90.90.7-0.9
Glucose0.00.00.10.1-0.10.20.30.20.0-0.0-0.2-0.1
Heart weight0.50.72.51.2-1.20.81.60.70.2-0.3-0.30.1
Delay discount hyperbolic model param0.10.10.2-0.40.40.10.10.10.4-0.4-0.20.0
Intermittent access intake day 1-15 change1.71.72.5-1.51.5-1.6-1.2-1.5-1.01.01.0-1.4
Intermittent access intake escalation2.12.13.0-1.71.7-1.7-1.4-1.6-1.01.01.0-1.4
Intermittent access intake escalation 22.72.73.3-1.81.8-1.8-1.3-1.8-1.51.51.5-1.8
Intermitt. access day 1 inactive lever presses0.70.71.5-0.10.1-0.30.4-0.7-1.21.21.2-1.2
Intermitt. access day 15 inactive lever presses0.30.40.60.6-0.60.70.30.70.6-0.6-0.60.5
Intermitt. access escalation Index0.50.52.3-0.70.7-0.6-1.5-0.5-0.20.20.2-0.4
Intermittent access day 1 total infusions1.11.31.91.4-1.41.30.81.31.0-1.0-1.00.9
Intermittent access day 15 total infusions0.00.00.10.1-0.10.0-0.00.0-0.00.00.0-0.3
Intermittent access terminal intake (last 3 days)0.00.00.10.2-0.20.30.20.2-0.00.00.0-0.3
Intermittent access total infusions0.20.20.40.6-0.60.50.20.50.4-0.4-0.40.2
Intermittent access day 1 locomotion0.40.40.80.9-0.90.80.70.70.3-0.3-0.30.2
Intermittent access day 15 total locomotion1.31.42.10.9-0.91.20.11.21.4-1.4-1.41.5
Intermittent access total locomotion1.61.82.21.2-1.21.40.41.41.5-1.5-1.51.5
Intermittent access standard deviation0.80.81.70.0-0.0-0.40.9-0.6-1.21.21.2-1.3
Left kidney weight0.10.30.8-0.70.7-0.7-0.9-0.50.1-0.2-0.10.2
Right kidney weight0.10.40.7-0.10.1-0.1-0.80.20.8-0.8-0.80.8
Cocaine induced anxiety0.00.00.20.1-0.10.20.30.0-0.20.20.2-0.5
Post-drug Anxiety0.80.91.31.0-1.01.11.01.00.8-0.8-0.80.7
Baseline Anxiety1.01.02.50.3-0.30.6-0.60.81.3-1.3-1.31.6
Tail length1.85.46.8-2.52.5-2.6-1.8-2.6-2.32.32.3-2.0
Length with tail0.51.73.0-1.71.7-1.5-1.4-1.4-0.90.90.9-0.6
Length without tail0.71.52.70.6-0.61.0-0.01.21.6-1.6-1.61.5
Times rat made contact with spout0.00.00.1-0.20.2-0.30.1-0.3-0.20.20.1-0.1
Lifetime Intake0.10.10.20.5-0.50.50.20.40.3-0.3-0.30.2
Liver weight, left0.71.14.2-1.41.4-1.1-2.1-0.80.1-0.2-0.10.4
Liver weight, right0.40.73.3-1.01.0-0.8-1.8-0.50.3-0.3-0.30.3
Locomotor activity1.11.85.00.3-0.30.7-0.11.01.7-1.7-1.82.2
Locomotor testing distance0.81.33.60.2-0.20.5-0.20.91.5-1.5-1.61.9
Locomotor testing rearing0.61.02.9-1.31.3-1.1-1.7-0.70.4-0.4-0.50.6
Locomotion in novel chamber1.51.93.70.8-0.80.7-0.41.31.8-1.8-1.91.8
Locomotion in novel chamber post-restriction0.20.30.5-0.40.4-0.5-0.1-0.5-0.60.60.6-0.7
Fecal boli incidents, locomotor time 11.21.31.9-1.31.3-1.4-1.1-1.3-0.90.90.8-1.2
Change in fecal boli incidents, locomotor task1.51.42.8-0.80.8-0.90.1-1.2-1.51.51.7-1.2
Time >=10cm from walls, locomotor time 10.00.00.1-0.20.2-0.20.2-0.1-0.10.1-0.10.1
Bouts of movement, locomotor time 10.40.41.70.3-0.3-0.00.6-0.1-0.70.70.7-1.3
Total resting periods, locomotor time 10.50.61.40.7-0.70.21.10.1-0.80.70.7-1.2
Rest time, locomotor task time 10.40.51.51.0-1.00.61.20.4-0.40.40.4-0.2
Distance moved, locomotor task time 10.60.71.5-0.00.00.3-0.50.51.1-1.1-1.21.2
Vertical activity count, locomotor time 12.02.15.8-2.12.1-1.5-2.4-1.10.3-0.3-0.40.1
Time >=10cm from walls, locomotor time 20.80.81.00.9-0.91.00.61.00.8-0.8-1.01.0
Bouts of movement, locomotor time 20.20.20.50.7-0.70.60.60.40.0-0.00.0-0.7
Total resting periods, locomotor time 20.10.10.40.4-0.40.30.20.30.1-0.00.0-0.7
Rest time, locomotor task time 20.20.20.4-0.60.6-0.6-0.4-0.6-0.30.30.4-0.4
Distance moved, locomotor task time 22.32.73.51.7-1.71.71.01.91.6-1.6-1.71.6
Vertical activity count, locomotor time 20.60.62.0-0.80.8-0.4-1.4-0.10.8-0.8-1.00.4
Light reinforcement 18.515.428.8-5.15.1-4.6-5.4-4.2-2.22.12.1-1.9
Light reinforcement 27.09.418.4-4.14.1-3.5-4.3-3.2-1.61.51.6-1.5
Bone: marrow area0.30.62.1-1.01.0-0.8-1.5-0.60.1-0.1-0.1-0.0
Bone: maximum diameter0.10.10.30.0-0.0-0.3-0.1-0.3-0.60.60.3-0.5
Bone: maximum force0.00.10.2-0.00.00.1-0.40.20.3-0.3-0.30.4
Bone: maximum moment0.00.10.20.0-0.00.1-0.40.20.4-0.4-0.30.4
Mean time between licks in bursts0.00.00.10.4-0.40.1-0.10.1-0.00.0-0.1-0.1
Mean num. licks in bursts0.30.41.30.3-0.30.21.2-0.0-0.60.60.8-0.7
Cd content in liver0.10.10.20.3-0.3-0.00.1-0.2-0.40.40.4-0.3
Co content in liver1.21.54.21.8-1.81.32.01.0-0.20.20.1-0.1
Cu content in liver0.50.60.90.9-0.90.90.30.80.8-0.8-0.70.8
Fe content in liver0.70.91.7-0.00.0-0.41.0-0.5-1.31.31.2-1.2
K content in liver0.20.20.20.4-0.40.40.40.50.4-0.4-0.40.5
Mg content in liver0.40.41.00.8-0.80.71.00.60.1-0.1-0.10.2
Mn content in liver0.10.10.10.2-0.20.2-0.40.20.3-0.3-0.40.3
Na content in liver0.10.10.3-0.50.5-0.3-0.2-0.20.1-0.1-0.20.3
Rb content in liver0.10.10.1-0.00.0-0.20.1-0.2-0.40.40.4-0.4
Se content in liver1.41.82.9-0.80.8-1.2-0.2-1.2-1.71.71.7-1.7
Sr content in liver0.80.70.90.9-0.90.90.50.90.8-0.8-0.70.9
Zn content in liver0.91.01.60.9-0.91.00.21.01.2-1.2-1.11.3
Bone: minimum diameter0.91.73.8-1.61.6-1.6-2.0-1.4-0.80.80.6-0.6
Time in familiar zone, hab. session 10.50.40.6-0.60.6-0.8-0.5-0.8-0.70.70.7-0.4
Time in novel zone, hab. session 10.70.71.80.8-0.80.91.30.90.7-0.7-0.70.7
Total zone transitions, hab. session 10.20.31.0-0.80.8-0.6-1.0-0.40.2-0.2-0.20.5
Total locomotion distance, hab. session 10.10.20.4-0.50.5-0.4-0.7-0.20.2-0.2-0.30.6
Locomotion velocity, hab. session 10.20.31.1-0.70.7-0.5-1.1-0.40.2-0.2-0.30.5
Time in familiar zone, hab. session 21.11.11.7-1.21.2-1.3-1.3-1.2-0.90.90.8-0.7
Time in novel zone, hab. session 23.73.74.41.8-1.82.11.52.12.0-2.0-1.91.9
Total zone transitions, hab. session 20.60.81.8-1.11.1-1.1-1.3-1.0-0.50.50.5-0.3
Total locomotion distance, hab. session 20.30.41.4-0.70.7-0.5-1.2-0.40.2-0.2-0.30.5
Locomotion velocity, hab. session 20.30.41.6-0.80.8-0.6-1.3-0.40.1-0.1-0.20.4
Novel to familiar place preference ratio0.70.71.10.7-0.70.80.30.91.0-1.0-1.00.8
Novelty place preference0.80.91.40.6-0.60.80.11.01.2-1.2-1.21.0
Time in novel zone, NPP test0.90.91.20.8-0.81.00.51.11.1-1.1-1.10.9
Total zone transitions, NPP test0.50.71.8-1.11.1-1.0-1.3-0.8-0.30.30.3-0.2
Total locomotion distance, NPP test0.10.10.3-0.40.4-0.3-0.6-0.30.0-0.0-0.10.2
Locomotion velocity, NPP test0.10.20.8-0.50.5-0.3-0.9-0.30.2-0.2-0.20.4
Intraocular pressure2.53.55.92.4-2.42.22.02.01.3-1.3-1.31.3
Delta distance traveled before/after self-admin0.00.00.1-0.00.00.00.3-0.1-0.20.20.3-0.2
Delta ambulatory time before/after self-admin0.50.50.9-0.60.6-0.7-0.3-0.8-0.90.90.9-0.9
Parametrial fat weight0.10.30.6-0.80.8-0.6-0.8-0.5-0.10.10.0-0.2
Pavlov. Cond. lever latency0.30.30.7-0.30.3-0.1-0.80.10.8-0.8-0.70.7
Pavlov. Cond. magazine entry latency0.40.52.40.8-0.80.71.50.5-0.20.20.10.0
Pavlov. Cond. change in total contacts1.01.02.1-0.40.4-0.70.3-0.8-1.41.41.3-1.3
Pavlov. Cond. index score0.40.51.90.7-0.70.51.40.2-0.70.70.5-0.5
Pavlov. Cond. latency score0.20.30.90.5-0.50.31.00.1-0.60.60.4-0.5
Pavlov. Cond. lever contacts0.30.30.90.4-0.40.21.00.0-0.70.70.5-0.6
Pavlov. Cond. magazine entry number0.81.04.2-1.11.1-0.8-2.1-0.50.6-0.6-0.50.5
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.00.0-0.20.0-0.4-0.70.70.9-0.8
Pavlov. Cond. lever-magazine prob. diff.0.60.73.01.1-1.10.81.70.6-0.40.40.3-0.3
Pavlov. Cond. response bias0.60.73.30.8-0.80.61.80.3-0.70.70.6-0.6
Pavlov. Cond. lever latency0.20.20.40.4-0.40.5-0.10.50.5-0.5-0.60.4
Pavlov. Cond. magazine entry latency0.00.00.00.1-0.10.00.10.10.1-0.1-0.10.1
Pavlov. Cond. change in total contacts0.30.41.0-0.20.2-0.40.5-0.5-0.90.91.0-0.8
Pavlov. Cond. index score0.20.20.4-0.20.2-0.40.4-0.4-0.60.60.6-0.5
Pavlov. Cond. latency score0.20.30.5-0.20.2-0.40.4-0.4-0.60.60.7-0.6
Pavlov. Cond. lever contacts0.10.20.3-0.50.5-0.5-0.1-0.5-0.30.30.4-0.3
Pavlov. Cond. magazine entry number0.00.10.3-0.10.10.0-0.50.10.2-0.2-0.20.2
Pavlov. Cond. intertrial magazine entries1.41.93.7-1.61.6-1.6-1.9-1.5-0.80.80.8-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.00.0-0.20.5-0.2-0.40.40.5-0.4
Pavlov. Cond. response bias0.00.00.1-0.10.1-0.10.2-0.1-0.10.10.1-0.1
Time in closed arm before self-admin0.70.81.7-0.40.4-0.70.2-0.9-1.31.31.3-1.1
Time in closed arm after self-admin0.10.10.40.4-0.40.20.60.1-0.30.30.4-0.4
Time in open arm before self-admin0.70.71.31.1-1.11.00.90.90.5-0.5-0.50.5
Time in open arm after self-admin0.40.51.00.2-0.20.3-0.40.50.9-0.9-1.01.0
Bone: periosteal estimation0.40.82.9-1.11.1-1.0-1.7-0.8-0.10.10.1-0.2
Bone: periosteal perimeter0.30.51.6-0.60.6-0.8-1.3-0.8-0.60.60.4-0.4
Bone: post-yield work0.60.81.7-1.31.3-1.1-1.2-0.9-0.40.40.2-0.4
Progressive ratio test 1 active lever presses1.71.72.51.5-1.51.61.11.51.2-1.2-1.21.0
Progressive ratio test 1 breakpoint1.41.42.01.4-1.41.41.11.31.0-1.0-1.00.9
Progressive ratio test 1 inactive lever presses0.10.10.40.4-0.40.60.20.30.1-0.1-0.1-0.1
Progressive ratio test 2 active lever presses0.60.61.01.0-1.00.90.70.90.6-0.6-0.60.4
Progressive ratio test 2 breakpoint0.91.01.21.1-1.11.10.71.11.0-1.0-1.00.8
Progressive ratio test 2 inactive lever presses1.72.03.01.6-1.61.71.01.61.2-1.2-1.21.3
Incentive Sensitization - Responses0.10.10.30.0-0.0-0.10.3-0.2-0.30.30.3-0.5
Incentive Sensitization - Breakpoint0.10.10.3-0.00.0-0.20.2-0.2-0.30.30.3-0.5
Sum of active levers in priming session hrs 5-60.60.52.2-0.90.9-0.8-1.5-0.6-0.10.1-0.0-0.0
Progressive ratio0.40.51.1-1.01.0-0.8-1.0-0.7-0.00.00.00.2
Food seeking constrained by brief footshock1.82.33.3-1.71.7-1.6-1.8-1.7-1.31.31.3-1.1
Seeking ratio, punishment vs. effort0.30.30.7-0.20.2-0.3-0.3-0.4-0.80.80.7-0.8
Retroperitoneal fat weight0.72.44.60.6-0.60.9-1.21.32.0-2.1-2.12.0
Reaction time number correct0.60.83.01.2-1.21.01.70.7-0.20.20.2-0.2
Reaction time mean minus median0.70.91.70.9-0.91.31.01.00.9-0.8-0.70.7
Reaction time mean minus median AUC1.52.03.41.6-1.61.81.51.61.1-1.1-1.11.0
Reaction time num false alarms2.12.83.81.9-1.91.81.01.91.5-1.5-1.61.7
Reaction time num false alarms AUC1.41.93.41.9-1.91.51.31.51.0-1.0-1.01.2
Reaction time trials correct on left0.60.83.01.2-1.21.01.70.7-0.20.20.2-0.2
Reaction time trials on left0.70.93.01.3-1.31.11.70.8-0.10.00.1-0.1
Reaction time mean3.95.57.72.6-2.62.82.22.62.1-2.0-2.01.9
Reaction time mean AUC3.95.37.32.6-2.62.72.32.62.0-1.9-1.91.8
Median of all reaction times4.35.97.92.8-2.82.82.32.72.2-2.1-2.02.0
Reaction time omissions2.94.04.91.9-1.92.20.82.22.1-2.1-2.22.2
Reaction time false alarm rate0.50.60.91.0-1.00.80.40.90.7-0.7-0.80.9
Reaction time premature initiation rate5.87.810.5-3.23.2-3.2-2.7-3.2-2.42.42.4-2.1
Reaction time premature initiations3.34.76.0-2.32.3-2.4-1.6-2.5-2.22.12.1-1.9
Std. dev. reaction times1.42.02.91.5-1.51.71.31.61.3-1.3-1.21.3
Reaction time trials completed0.70.93.01.3-1.31.11.70.8-0.10.00.1-0.1
Reaction time trials AUC0.71.03.01.4-1.41.21.70.90.1-0.1-0.10.1
Run reversals in cocaine runway, females3.53.45.21.3-1.31.70.41.92.3-2.3-2.22.3
Run reversals in cocaine runway, males0.80.81.41.2-1.21.00.90.90.5-0.5-0.50.7
Latency to leave start box in cocaine runway1.21.32.50.2-0.20.6-0.31.01.6-1.6-1.51.5
Latency to leave start box in cocaine runway, F1.01.01.70.6-0.61.00.51.11.3-1.3-1.21.2
Latency to leave start box in cocaine runway, M1.00.93.1-1.11.1-0.9-1.8-0.40.7-0.7-0.70.8
Std. dev. time between licks in bursts0.81.02.5-1.01.0-1.2-1.6-1.1-0.70.70.6-0.8
Total sessions with >9 infusions1.21.44.31.5-1.51.62.10.9-0.10.10.1-0.1
Short access day 1 total inactive lever presses0.10.10.3-0.50.50.1-0.6-0.10.2-0.2-0.20.3
Short access day 10 total inactive lever presses1.61.82.2-1.21.2-1.2-0.9-1.4-1.51.51.5-1.4
Short access day 1 total infusions1.51.63.81.5-1.51.92.01.20.3-0.3-0.30.2
Short access day 10 total infusions0.20.20.30.3-0.30.3-0.30.40.5-0.5-0.50.5
Short access total infusions0.20.20.50.5-0.50.70.30.50.4-0.4-0.40.3
Short access day 1 locomotion1.01.02.41.3-1.31.61.51.00.3-0.3-0.30.4
Short access day 10 total locomotion0.50.50.91.0-1.00.90.90.80.4-0.4-0.40.4
Short access total locomotion0.90.92.11.2-1.21.31.50.90.2-0.2-0.20.3
One hour access (0.3 mA shock)0.00.00.10.3-0.30.10.20.20.1-0.1-0.10.0
Compulsive drug intake1.81.83.4-0.50.5-1.10.3-1.3-1.91.91.8-1.7
One hour access (shock baseline)1.11.31.90.9-0.91.00.31.21.4-1.4-1.41.1
Social response proportion1.51.63.50.9-0.91.0-0.21.21.4-1.5-1.61.9
Social responses0.40.61.60.2-0.20.1-0.80.30.9-0.9-1.01.3
Social time0.40.51.0-0.30.3-0.7-0.5-0.8-1.00.90.8-0.7
Soleus weight0.10.30.50.0-0.00.3-0.70.30.7-0.7-0.60.6
Bone: stiffness0.20.30.7-0.40.4-0.2-0.90.20.7-0.7-0.70.7
Tibialis anterior weight0.10.40.80.9-0.90.80.60.70.3-0.3-0.40.4
Time to tail flick, vehicle, before self-admin0.40.50.8-0.90.9-0.8-0.4-0.8-0.60.60.5-0.4
Time to tail flick, vehicle, after self-admin0.91.03.2-1.31.3-1.0-1.8-0.60.5-0.5-0.50.5
Time to tail flick, test, before self-admin1.71.62.61.2-1.21.60.91.51.3-1.2-1.11.2
Time to tail flick, test, after self-admin0.10.10.2-0.40.4-0.20.1-0.20.2-0.2-0.10.1
Delta time to tail flick, vehicle, before/after SA0.30.31.1-0.60.6-0.5-1.0-0.40.2-0.2-0.1-0.0
Delta time to tail flick, test, before/after SA0.10.10.2-0.20.2-0.30.5-0.3-0.20.20.2-0.1
Tibia length0.20.50.9-0.40.4-0.50.4-0.6-1.00.90.9-0.9
Ambulatory time before self-admin1.51.62.11.2-1.21.50.61.41.3-1.4-1.41.2
Ambulatory time after self-admin0.10.10.30.2-0.20.40.20.40.4-0.5-0.50.2
Bone: tissue strength0.50.51.11.0-1.00.81.10.70.2-0.2-0.10.2
Total heroin consumption0.60.71.90.1-0.10.3-0.20.61.1-1.1-1.11.4
Bone: trabecular number6.09.311.4-2.92.9-3.3-1.5-3.4-3.33.33.2-3.1
Bone: trabecular spacing4.86.27.92.6-2.62.71.42.82.6-2.6-2.52.3
Bone: trabecular thickness0.81.01.7-1.31.3-1.2-0.8-1.1-0.80.80.8-0.5
Bone: trabecular tissue density2.53.64.61.6-1.61.91.12.12.1-2.1-2.12.0
Water consumed over 24 hours1.01.22.4-1.51.5-1.3-1.4-1.2-0.40.40.4-0.3
Number of responses in last shaping day1.21.32.61.6-1.61.61.51.10.4-0.4-0.40.3