Hub : Genes

MAST1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression MAST1 0.3 0.12 0.0e+00 0.23 0.22 0.23 0.23 3.6e-21 3.0e-20 1.1e-21 1.7e-21
2 PL gene expression MAST1 0.15 0.07 6.1e-12 0.1 0.11 0.1 0.1 6.8e-11 1.4e-11 1.5e-11 2.6e-11
3 BLA gene expression MAST1 0.13 0.07 1.5e-03 0.05 0.02 0.05 0.04 1.0e-03 4.8e-02 1.8e-03 2.5e-03
4 NAcc gene expression MAST1 0.12 0.06 1.8e-12 0.08 0.07 0.07 0.07 2.5e-12 1.9e-10 3.6e-11 2.1e-11
5 IC gene expression MAST1 0.39 0.15 1.2e-08 0.19 0.17 0.2 0.19 1.7e-08 1.2e-07 8.5e-09 2.9e-08
6 Brain mRNA stability MAST1 0.09 0.04 2.4e-06 0.06 0.07 0.07 0.07 1.4e-06 2.9e-07 8.1e-07 7.8e-07
7 IL gene expression MAST1 0.16 0.09 8.8e-03 0.05 0.06 0.06 0.04 2.3e-02 1.4e-02 1.3e-02 3.4e-02
8 OFC gene expression MAST1 0.47 0.15 1.1e-06 0.19 0.13 0.16 0.16 2.8e-05 5.7e-04 1.1e-04 9.7e-05
9 IC intron excision ratio chr19_40121006_40122784 0.09 0.06 6.0e-03 0.05 0.02 0 0.03 5.4e-03 6.7e-02 3.0e-01 2.1e-02
10 IC intron excision ratio chr19_40121353_40122784 0.09 0.06 4.4e-03 0.05 0.02 0 0.04 3.6e-03 5.1e-02 2.3e-01 1.1e-02
11 PL mRNA stability MAST1 0.06 0.03 6.6e-06 0.04 0.05 0.04 0.04 9.8e-05 5.4e-06 2.1e-05 1.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density3.55.99.42.73.03.12.22.5-2.72.52.32.1-2.1-1.3
Area under the delay curve0.20.20.9-0.20.00.5-0.30.5-0.90.20.40.5-0.5-0.5
BMI with tail1.55.310.1-2.9-3.2-2.6-2.2-1.92.0-2.8-2.3-1.41.41.9
BMI without tail0.00.10.3-0.5-0.60.0-0.20.4-0.4-0.3-0.00.5-0.50.1
Body weight0.20.72.2-0.6-0.7-1.00.3-0.61.5-0.7-0.9-0.30.31.1
Weight adjusted by age0.30.40.7-0.8-0.6-0.7-0.9-0.80.2-0.4-0.4-0.80.8-0.1
Bone surface3.97.19.82.73.02.82.42.6-2.73.13.02.2-2.2-2.4
Bone volume4.07.110.32.83.22.92.42.5-2.73.23.02.1-2.1-2.3
Breakpoint value in progressive ratio session1.21.44.60.0-0.3-0.70.3-0.91.9-1.3-1.7-0.90.92.1
Number of licking bursts0.20.40.80.30.10.60.80.8-0.1-0.3-0.30.9-0.90.9
Context. condit. distance diff. score1.41.73.3-1.7-1.8-1.6-1.1-0.91.5-1.6-1.4-0.50.51.1
Locomotion velocity, session 11.21.32.41.41.51.31.21.2-0.91.21.01.0-1.0-0.6
Locomotion distance, session 10.20.30.90.20.30.30.80.40.5-0.2-0.40.5-0.51.0
Locomotion velocity, session 20.60.71.30.90.81.10.81.1-0.70.50.51.1-1.10.1
Locomotion distance, session 20.50.82.7-0.5-0.5-0.60.4-0.41.4-1.1-1.1-0.20.21.6
Locomotion velocity, session 30.10.10.4-0.2-0.00.1-0.50.2-0.40.30.40.3-0.3-0.7
Locomotion distance, session 32.42.65.50.60.71.50.92.1-1.71.31.62.3-2.3-1.5
Stereotopy head waving bouts, day 30.50.52.6-0.6-0.5-0.3-1.1-0.1-0.90.50.70.1-0.1-1.6
Stereotopy head waving duration, day 30.20.31.1-0.7-0.7-0.5-1.0-0.3-0.3-0.2-0.0-0.20.2-0.5
Locomotion velocity, session 70.20.20.7-0.5-0.7-0.20.00.50.2-0.4-0.10.8-0.80.1
Locomotion distance, session 70.20.30.80.40.30.40.90.60.3-0.1-0.10.6-0.60.7
Stereotopy head waving bouts, day 70.91.02.50.20.30.8-0.11.0-1.60.91.21.1-1.1-1.5
Stereotopy head waving duration, day 71.31.53.40.80.81.20.41.3-1.81.21.41.3-1.3-1.4
Locomotion velocity, session 80.20.31.3-0.1-0.1-0.30.60.21.1-0.3-0.50.5-0.50.8
Locomotion distance, session 80.91.33.3-1.1-1.2-1.0-0.0-0.31.7-1.6-1.50.1-0.11.8
Degree of sensitization distance1.41.43.2-0.1-0.4-1.00.1-1.31.8-1.1-1.3-1.31.31.7
Degree of sensitization stereotypy0.50.61.40.20.10.60.20.8-1.20.60.80.9-0.9-1.0
Conditioned locomotion0.10.10.20.30.30.10.50.20.20.20.10.3-0.30.1
Cocaine response after cond. corrected1.01.33.0-0.6-0.9-1.1-0.2-0.91.7-1.3-1.5-0.80.81.5
Cocaine response after cond. not corrected1.11.23.1-0.6-0.8-1.0-0.2-0.81.7-1.3-1.5-0.70.71.8
Cocaine response before conditioning0.50.61.00.50.70.90.41.0-0.90.70.91.0-1.0-0.4
Saline control response1.21.65.01.51.11.22.21.20.5-0.1-0.41.0-1.01.8
Bone: connectivity density6.610.315.53.43.43.92.83.5-3.63.23.23.0-3.0-2.0
Bone: cortical apparent density0.20.30.8-0.3-0.80.3-0.60.4-0.9-0.40.10.5-0.5-0.2
Bone: cortical area0.10.20.50.10.2-0.10.60.20.7-0.0-0.20.4-0.40.5
Bone: cortical porosity1.21.32.4-1.2-1.0-1.5-0.8-1.31.6-1.0-1.2-1.11.10.7
Bone: cortical porosity0.60.61.7-1.0-0.8-1.2-0.4-0.81.3-0.6-0.8-0.60.60.3
Bone: cortical thickness1.21.93.1-1.6-1.7-1.7-1.0-1.11.8-1.7-1.5-0.70.71.4
Bone: cortical thickness2.42.810.8-1.0-1.2-0.8-0.5-0.91.7-2.5-2.4-0.80.83.3
Bone: cortical tissue density0.20.31.0-0.3-0.70.3-0.50.5-1.0-0.20.30.7-0.7-0.4
Condit. Reinf. active minus inactive responses0.70.82.4-1.6-1.4-0.7-0.60.5-0.1-0.30.21.2-1.2-0.6
Condit. Reinf. active-inactive response ratio1.01.12.9-1.6-1.7-1.2-0.6-0.21.0-1.2-0.90.4-0.40.7
Condit. Reinf. active responses0.60.71.8-0.8-0.60.0-0.20.9-0.80.40.91.4-1.4-1.0
Condit. Reinf. inactive responses2.83.45.11.82.02.01.41.8-2.02.12.31.6-1.6-1.7
Incentive salience index mean1.31.63.5-0.30.00.60.11.5-1.41.11.61.9-1.9-1.6
Condit. Reinf. lever presses2.53.56.70.91.41.60.51.9-2.32.32.61.9-1.9-2.4
Condit. Reinf. active minus inactive responses0.20.30.60.40.40.30.40.7-0.10.60.60.8-0.8-0.6
Condit. Reinf. active-inactive response ratio0.10.20.4-0.3-0.2-0.6-0.6-0.50.6-0.1-0.2-0.40.4-0.0
Condit. Reinf. active responses0.10.10.40.40.40.20.60.40.20.20.10.5-0.50.1
Condit. Reinf. inactive responses0.20.31.2-0.0-0.1-0.20.4-0.40.7-0.7-0.8-0.50.51.1
Condit. Reinf. lever presses0.00.00.0-0.1-0.10.0-0.1-0.0-0.1-0.10.0-0.10.1-0.1
Condit. Reinf. lever reinforcers received0.10.10.20.40.30.20.40.30.00.20.10.3-0.3-0.0
Conditioned reinforcement - actives0.00.00.0-0.10.1-0.2-0.10.00.20.0-0.10.1-0.10.0
Conditioned reinforcement - inactives0.00.00.1-0.2-0.2-0.2-0.30.10.2-0.0-0.10.2-0.2-0.3
Conditioned locomotion0.10.10.3-0.1-0.10.1-0.10.4-0.20.10.20.5-0.5-0.5
Patch foraging indifference point 0 sec0.10.30.6-0.2-0.2-0.20.40.50.10.50.50.8-0.8-0.8
Patch foraging indifference point AUC0.81.13.01.71.71.41.40.7-0.70.90.60.2-0.20.1
Delay disc. indifference point, 0s delay1.61.72.61.31.61.51.01.2-1.51.41.31.0-1.0-1.2
Delay disc. indifference point, 16s delay1.11.21.8-1.0-1.1-0.9-1.0-1.10.8-1.4-1.3-1.11.11.0
Delay disc. indifference point, 2s delay0.30.31.4-1.0-0.6-0.3-1.2-0.2-0.5-0.2-0.0-0.10.1-0.5
Delay disc. indifference point, 24s delay0.20.20.7-0.6-0.8-0.7-0.3-0.30.6-0.4-0.2-0.10.10.1
Delay disc. indifference point, 4s delay2.02.15.20.71.21.70.21.5-2.31.31.61.4-1.4-1.6
Delay disc. indifference point, 8s delay0.20.30.8-0.2-0.10.5-0.20.6-0.90.10.50.7-0.7-0.5
Indifference point function ln k0.50.92.9-1.7-1.6-1.1-1.4-0.4-0.0-0.40.00.1-0.1-1.0
Indifference point function log k0.50.92.9-1.7-1.6-1.1-1.4-0.4-0.0-0.40.00.1-0.1-1.0
Patch foraging total patch changes 0 sec0.10.20.4-0.6-0.6-0.60.00.00.50.10.10.4-0.4-0.5
Patch foraging total patch changes 12 sec1.11.43.11.01.01.11.81.5-0.30.90.71.6-1.60.1
Patch foraging total patch changes 18 sec2.03.06.42.02.11.92.51.9-0.81.51.21.8-1.8-0.1
Patch foraging total patch changes 24 sec1.32.33.61.81.61.51.91.6-1.01.61.51.4-1.4-0.9
Patch foraging total patch changes 6 sec0.30.51.00.80.80.91.00.8-0.40.60.50.7-0.70.1
Patch foraging time to switch 0 sec0.00.10.40.00.10.00.3-0.10.2-0.2-0.4-0.20.20.6
Patch foraging water rate 0 sec0.00.10.3-0.0-0.1-0.4-0.0-0.40.50.0-0.0-0.40.40.0
Patch foraging water rate 12 sec0.20.51.6-0.5-0.30.3-0.80.5-1.30.30.80.6-0.6-1.1
Patch foraging water rate 18 sec1.93.06.40.60.71.40.11.8-2.31.72.31.9-1.9-2.5
Patch foraging water rate 24 sec0.71.02.3-0.1-0.20.5-0.31.1-1.20.71.21.3-1.3-1.5
Patch foraging water rate 6 sec2.53.75.42.32.32.32.32.1-1.41.71.51.9-1.9-0.4
Seeking ratio, delayed vs. immediate footshock0.81.02.4-1.5-1.4-0.8-1.5-0.60.1-1.1-0.8-0.50.50.5
Distance traveled before self-admin0.71.01.8-1.2-1.1-1.2-1.3-1.20.5-0.7-0.6-1.11.1-0.2
Distance traveled after self-admin1.01.22.0-1.3-1.0-1.2-1.4-1.40.4-0.8-0.6-1.41.4-0.0
Extensor digitorum longus weight0.52.14.6-1.0-1.0-1.6-0.6-1.62.1-1.4-1.6-1.51.51.7
Bone: elastic displacement0.20.20.7-0.8-0.8-0.7-0.6-0.20.2-0.10.10.0-0.0-0.5
Bone: elastic work1.51.93.4-1.8-1.8-1.9-1.4-1.31.5-1.3-1.2-1.01.00.6
Bone: endosteal estimation0.20.41.30.50.80.31.10.30.60.0-0.40.3-0.30.9
Bone: endosteal perimeter0.61.22.91.01.30.81.71.20.11.10.71.4-1.4-0.2
Epididymis fat weight0.00.10.4-0.0-0.1-0.30.40.10.70.1-0.00.3-0.30.2
Delta time in closed arm before/after self-admin0.20.20.6-0.8-0.7-0.4-0.6-0.1-0.1-0.3-0.00.0-0.0-0.1
Delta time in open arm before/after self-admin1.01.03.81.71.40.72.00.20.80.5-0.2-0.10.11.0
Diff in mean of infusions in LGA sessions0.20.20.40.60.60.60.60.5-0.10.2-0.00.4-0.40.5
Delay discount exponential model param0.30.31.00.20.0-0.50.3-0.61.0-0.2-0.5-0.70.70.6
Extinction: sum of active levers before priming0.60.72.3-1.5-1.3-0.6-1.4-0.3-0.5-0.6-0.0-0.10.1-0.4
Active lever presses in extinction session 60.60.62.4-0.6-0.30.0-0.70.3-1.10.60.90.5-0.5-1.6
Bone: final force0.10.20.90.20.3-0.30.4-0.40.9-0.2-0.4-0.40.40.8
Bone: final moment0.10.21.00.00.1-0.40.2-0.41.0-0.3-0.5-0.40.40.8
Food consumed during 24 hour testing period3.14.39.02.82.82.73.02.2-1.01.41.01.7-1.70.8
Glucose0.30.51.40.1-0.1-0.70.4-1.01.2-0.2-0.5-1.11.10.4
Heart weight0.30.51.2-1.0-1.1-0.0-1.00.1-0.8-0.9-0.40.2-0.20.2
Delay discount hyperbolic model param0.40.51.50.2-0.1-0.70.3-0.81.2-0.3-0.6-0.90.90.7
Intermittent access intake day 1-15 change1.32.63.61.81.91.91.91.7-1.41.71.51.5-1.5-0.8
Intermittent access intake escalation0.81.62.21.31.41.51.51.4-1.21.31.21.3-1.3-0.5
Intermittent access intake escalation 21.72.02.81.51.51.61.71.5-1.31.41.31.3-1.3-0.6
Intermitt. access day 1 inactive lever presses0.31.23.70.70.90.70.40.9-1.11.31.31.0-1.0-1.9
Intermitt. access day 15 inactive lever presses0.40.81.2-1.0-0.9-1.1-1.1-0.81.1-0.8-0.9-0.60.60.3
Intermitt. access escalation Index0.20.20.6-0.3-0.40.3-0.40.4-0.80.10.40.5-0.5-0.6
Intermittent access day 1 total infusions1.62.53.9-1.9-1.7-1.9-2.0-1.61.4-1.6-1.5-1.41.40.6
Intermittent access day 15 total infusions0.30.40.9-1.0-0.8-0.8-0.9-0.60.4-0.6-0.6-0.40.40.0
Intermittent access terminal intake (last 3 days)0.40.50.9-0.9-0.7-0.9-1.0-0.70.6-0.5-0.6-0.60.6-0.1
Intermittent access total infusions1.01.11.8-1.2-1.1-1.3-1.3-1.11.0-1.0-1.1-0.90.90.3
Intermittent access day 1 locomotion0.81.12.5-1.5-1.4-1.1-1.6-0.80.6-1.0-0.9-0.60.60.1
Intermittent access day 15 total locomotion1.01.82.3-1.3-1.3-1.5-1.2-1.51.4-1.3-1.4-1.51.50.9
Intermittent access total locomotion2.12.53.4-1.6-1.6-1.7-1.5-1.51.7-1.8-1.8-1.41.41.2
Intermittent access standard deviation0.40.91.20.91.01.00.81.0-0.91.10.90.9-0.9-0.9
Left kidney weight0.73.26.92.11.71.82.62.2-0.61.31.22.1-2.10.3
Right kidney weight0.41.86.51.61.10.92.51.40.60.60.31.5-1.51.0
Cocaine induced anxiety0.30.41.5-0.5-0.2-0.1-0.60.5-0.60.40.70.7-0.7-1.2
Post-drug Anxiety0.20.20.5-0.7-0.6-0.5-0.7-0.30.1-0.4-0.2-0.10.1-0.1
Baseline Anxiety0.60.72.70.0-0.2-0.30.2-0.80.9-0.9-1.2-0.90.91.6
Tail length2.49.515.23.63.93.43.23.0-2.63.53.02.5-2.5-2.0
Length with tail0.52.25.22.12.31.32.31.0-0.41.91.20.8-0.8-0.7
Length without tail0.51.54.2-0.5-0.6-1.4-0.0-1.42.1-0.9-1.3-1.41.41.3
Times rat made contact with spout0.10.10.3-0.00.10.4-0.20.4-0.6-0.00.10.3-0.30.1
Lifetime Intake0.60.71.3-1.0-0.8-1.2-1.1-0.90.9-0.7-0.8-0.70.70.1
Liver weight, left0.40.62.11.01.00.41.40.4-0.11.00.60.3-0.3-0.7
Liver weight, right0.81.33.31.21.20.81.81.0-0.31.41.21.1-1.1-0.9
Locomotor activity0.91.43.5-0.8-0.6-0.9-0.3-1.11.4-1.4-1.6-1.11.11.9
Locomotor testing distance0.81.42.8-0.8-0.6-0.9-0.3-1.31.3-1.3-1.4-1.41.41.7
Locomotor testing rearing0.40.92.50.90.81.01.60.80.1-0.2-0.40.7-0.71.6
Locomotion in novel chamber0.70.93.7-0.6-0.7-0.5-0.4-0.41.1-1.3-1.4-0.30.31.9
Locomotion in novel chamber post-restriction0.50.81.21.00.90.80.70.7-0.81.11.00.6-0.6-1.1
Fecal boli incidents, locomotor time 10.81.12.31.31.30.61.50.9-0.11.41.00.9-0.9-0.7
Change in fecal boli incidents, locomotor task2.12.05.10.91.01.80.51.6-2.31.11.51.5-1.5-1.3
Time >=10cm from walls, locomotor time 10.10.10.30.20.30.50.00.2-0.6-0.1-0.10.1-0.10.2
Bouts of movement, locomotor time 10.20.20.8-0.5-0.0-0.0-0.70.0-0.70.40.50.1-0.1-0.9
Total resting periods, locomotor time 10.40.41.2-0.9-0.3-0.2-1.1-0.0-0.80.30.60.1-0.1-1.1
Rest time, locomotor task time 10.30.41.4-1.2-0.8-1.0-1.0-0.40.3-0.1-0.0-0.10.1-0.5
Distance moved, locomotor task time 10.30.51.50.2-0.2-0.10.2-0.60.7-0.9-1.1-0.80.81.2
Vertical activity count, locomotor time 10.61.55.02.21.61.52.20.60.20.2-0.30.2-0.21.3
Time >=10cm from walls, locomotor time 20.71.12.6-0.6-0.5-0.9-1.1-1.50.6-0.7-0.9-1.61.60.2
Bouts of movement, locomotor time 20.10.20.8-0.6-0.40.2-0.8-0.0-0.9-0.20.3-0.00.0-0.4
Total resting periods, locomotor time 20.10.10.6-0.4-0.10.3-0.60.0-0.8-0.10.30.0-0.0-0.2
Rest time, locomotor task time 20.10.10.30.20.50.30.30.5-0.30.30.20.5-0.5-0.0
Distance moved, locomotor task time 22.32.83.9-1.4-1.6-1.7-1.4-2.01.6-1.7-1.7-2.02.01.1
Vertical activity count, locomotor time 20.50.72.21.10.60.31.2-0.11.0-0.4-0.9-0.30.31.5
Light reinforcement 14.811.827.94.94.43.85.33.5-1.22.82.03.0-3.00.4
Light reinforcement 23.96.016.44.03.62.64.01.9-0.62.31.51.3-1.30.2
Bone: marrow area0.20.41.20.50.80.31.10.30.6-0.0-0.40.3-0.31.0
Bone: maximum diameter0.10.20.6-0.20.0-0.20.50.40.40.40.20.8-0.8-0.4
Bone: maximum force0.20.31.20.10.0-0.50.2-0.61.1-0.2-0.5-0.60.60.6
Bone: maximum moment0.20.31.2-0.1-0.1-0.60.1-0.51.1-0.3-0.5-0.50.50.6
Mean time between licks in bursts0.20.51.70.1-0.10.50.71.1-0.40.00.31.3-1.30.1
Mean num. licks in bursts0.30.41.3-0.30.0-0.1-1.0-0.5-0.70.50.6-0.60.6-1.1
Cd content in liver3.03.37.2-2.4-2.7-2.1-1.2-1.21.8-2.4-2.0-0.60.61.6
Co content in liver1.41.75.0-2.2-2.2-1.8-1.5-1.00.5-1.0-0.5-0.50.5-0.6
Cu content in liver0.60.71.5-0.9-1.1-1.1-0.2-0.51.2-1.0-0.9-0.20.20.9
Fe content in liver1.72.06.90.91.30.90.10.5-1.72.12.10.3-0.3-2.6
K content in liver0.50.50.8-0.7-0.8-0.9-0.8-0.90.6-0.4-0.4-0.90.9-0.1
Mg content in liver0.10.10.5-0.3-0.4-0.6-0.3-0.40.20.20.2-0.30.3-0.7
Mn content in liver0.20.30.90.40.10.10.90.60.40.00.00.7-0.70.4
Na content in liver0.20.20.50.60.70.50.1-0.1-0.40.70.5-0.40.4-0.6
Rb content in liver0.40.51.00.80.50.70.90.9-0.30.50.61.0-1.0-0.2
Se content in liver1.11.44.20.91.30.40.70.4-0.62.01.70.3-0.3-2.1
Sr content in liver1.00.91.8-1.1-1.3-1.3-0.5-0.81.2-0.9-0.8-0.60.60.6
Zn content in liver1.21.32.4-1.4-1.5-1.5-1.0-1.01.3-1.3-1.2-0.70.70.7
Bone: minimum diameter0.61.12.91.21.61.01.71.1-0.10.90.51.0-1.00.2
Time in familiar zone, hab. session 11.21.22.70.80.51.20.91.5-1.10.50.71.6-1.6-0.3
Time in novel zone, hab. session 11.21.22.8-1.0-0.7-0.9-1.4-1.50.3-0.7-0.6-1.71.70.1
Total zone transitions, hab. session 10.10.10.50.40.60.40.50.00.1-0.0-0.2-0.20.20.7
Total locomotion distance, hab. session 10.00.10.30.10.30.20.2-0.10.2-0.1-0.2-0.20.20.6
Locomotion velocity, hab. session 10.10.10.50.30.50.20.60.00.4-0.0-0.2-0.10.10.7
Time in familiar zone, hab. session 21.31.42.31.41.11.31.51.4-0.70.90.91.4-1.4-0.2
Time in novel zone, hab. session 23.63.74.6-2.1-2.1-2.0-1.8-2.01.6-2.1-2.0-1.91.91.4
Total zone transitions, hab. session 20.60.81.40.80.91.11.11.2-0.60.50.51.2-1.20.3
Total locomotion distance, hab. session 20.20.20.90.40.40.20.90.20.5-0.1-0.20.1-0.10.8
Locomotion velocity, hab. session 20.20.20.80.50.50.20.90.10.50.0-0.20.0-0.00.8
Novel to familiar place preference ratio0.80.81.5-1.0-1.0-0.7-1.0-0.80.6-1.2-1.1-0.80.81.0
Novelty place preference0.91.01.8-0.9-0.9-0.7-1.0-0.90.7-1.3-1.3-0.90.91.2
Time in novel zone, NPP test1.01.11.6-1.1-1.0-0.8-1.2-1.00.5-1.3-1.2-1.11.10.9
Total zone transitions, NPP test0.40.61.90.80.80.61.40.90.30.50.30.9-0.90.5
Total locomotion distance, NPP test0.10.10.20.10.20.10.40.30.2-0.0-0.00.4-0.40.4
Locomotion velocity, NPP test0.10.20.60.10.2-0.10.60.20.8-0.1-0.20.4-0.40.7
Intraocular pressure1.31.94.1-1.8-2.0-1.6-1.8-1.40.7-1.3-0.9-1.21.20.1
Delta distance traveled before/after self-admin0.10.10.20.30.40.40.20.1-0.30.20.20.0-0.00.1
Delta ambulatory time before/after self-admin0.70.81.40.90.91.20.81.0-1.00.80.90.9-0.9-0.3
Parametrial fat weight0.20.41.90.70.4-0.11.4-0.30.90.0-0.3-0.40.40.9
Pavlov. Cond. lever latency0.30.31.70.2-0.20.20.50.10.4-0.9-0.80.1-0.11.3
Pavlov. Cond. magazine entry latency0.30.41.5-0.7-0.3-0.3-1.1-0.4-0.60.40.6-0.40.4-1.2
Pavlov. Cond. change in total contacts1.01.13.10.40.80.60.20.8-1.01.51.50.8-0.8-1.7
Pavlov. Cond. index score0.40.52.1-0.7-0.3-0.5-0.9-0.3-0.40.60.7-0.20.2-1.4
Pavlov. Cond. latency score0.20.31.4-0.5-0.2-0.4-0.7-0.2-0.30.60.6-0.10.1-1.2
Pavlov. Cond. lever contacts0.40.52.1-0.5-0.0-0.4-0.9-0.3-0.40.80.8-0.30.3-1.5
Pavlov. Cond. magazine entry number0.70.92.41.10.80.91.50.90.3-0.2-0.40.9-0.91.4
Pavlov. Cond. intertrial magazine entries0.30.40.80.30.20.00.90.5-0.00.80.80.7-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.72.0-1.0-0.6-0.9-1.3-0.8-0.10.40.5-0.70.7-1.4
Pavlov. Cond. response bias0.70.83.8-0.7-0.2-0.4-1.3-0.4-1.00.81.0-0.40.4-2.0
Pavlov. Cond. lever latency0.30.40.7-0.5-0.6-0.8-0.4-0.70.8-0.6-0.6-0.60.60.4
Pavlov. Cond. magazine entry latency0.00.00.2-0.2-0.00.0-0.00.3-0.0-0.1-0.00.4-0.40.1
Pavlov. Cond. change in total contacts0.40.61.40.40.40.80.20.9-1.20.70.90.9-0.9-1.0
Pavlov. Cond. index score0.30.40.70.40.40.70.20.7-0.90.60.70.6-0.6-0.6
Pavlov. Cond. latency score0.30.40.80.40.50.70.20.7-0.90.70.80.7-0.7-0.7
Pavlov. Cond. lever contacts0.30.40.80.60.60.90.50.8-0.80.40.50.7-0.7-0.2
Pavlov. Cond. magazine entry number0.00.00.1-0.2-0.2-0.1-0.2-0.20.2-0.3-0.2-0.20.20.3
Pavlov. Cond. intertrial magazine entries1.31.93.91.71.71.62.01.5-0.81.21.01.4-1.4-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.30.30.60.10.6-0.80.50.60.6-0.6-0.6
Pavlov. Cond. response bias0.10.10.20.30.20.40.20.4-0.30.20.20.3-0.3-0.1
Time in closed arm before self-admin1.72.22.91.01.21.40.71.7-1.71.51.61.7-1.7-1.6
Time in closed arm after self-admin1.01.12.40.20.40.80.21.4-1.20.81.11.5-1.5-1.1
Time in open arm before self-admin0.60.61.2-1.1-1.0-0.7-1.0-0.80.2-0.9-0.6-0.80.80.4
Time in open arm after self-admin0.70.71.2-0.3-0.5-0.7-0.2-1.01.1-0.8-1.0-1.11.11.0
Bone: periosteal estimation0.20.51.70.60.80.41.30.60.70.1-0.30.7-0.70.9
Bone: periosteal perimeter0.50.92.30.50.50.41.51.20.40.50.31.5-1.50.1
Bone: post-yield work0.10.20.80.70.90.40.50.00.00.3-0.0-0.20.20.5
Progressive ratio test 1 active lever presses1.01.32.0-1.2-1.1-1.4-1.3-1.11.3-1.1-1.2-0.90.90.5
Progressive ratio test 1 breakpoint1.21.42.2-1.2-1.2-1.5-1.4-1.21.3-1.2-1.3-1.01.00.5
Progressive ratio test 1 inactive lever presses0.20.40.9-0.6-0.5-1.0-0.8-0.50.8-0.4-0.5-0.20.2-0.5
Progressive ratio test 2 active lever presses1.21.42.0-1.3-1.2-1.4-1.3-1.21.2-1.2-1.2-1.11.10.7
Progressive ratio test 2 breakpoint1.41.62.2-1.4-1.2-1.5-1.4-1.31.2-1.3-1.3-1.21.20.7
Progressive ratio test 2 inactive lever presses1.32.13.2-1.8-1.7-1.7-1.8-1.41.3-1.5-1.4-1.21.20.6
Incentive Sensitization - Responses0.30.40.9-0.5-0.5-0.6-0.5-0.80.5-0.6-0.6-0.90.90.6
Incentive Sensitization - Breakpoint0.30.30.8-0.4-0.4-0.5-0.4-0.70.4-0.5-0.5-0.90.90.5
Sum of active levers in priming session hrs 5-60.20.21.10.1-0.10.10.2-0.10.3-0.5-0.6-0.20.21.0
Progressive ratio0.20.31.20.80.40.41.00.30.4-0.1-0.30.1-0.11.1
Food seeking constrained by brief footshock1.62.04.01.61.51.22.01.5-0.61.41.41.5-1.5-0.7
Seeking ratio, punishment vs. effort0.40.51.30.60.70.30.70.5-0.41.11.00.6-0.6-1.2
Retroperitoneal fat weight0.20.83.60.0-0.1-0.81.2-0.31.9-0.5-0.8-0.00.01.6
Reaction time number correct0.20.51.4-1.2-0.9-0.5-1.20.1-0.4-0.10.30.4-0.4-0.8
Reaction time mean minus median0.61.52.4-1.1-1.2-1.5-1.1-1.51.1-0.9-1.2-1.51.50.3
Reaction time mean minus median AUC1.12.74.4-1.7-1.7-2.1-1.6-2.01.5-1.3-1.4-1.91.90.3
Reaction time num false alarms1.62.24.9-2.2-2.1-1.7-1.1-0.71.6-1.8-1.6-0.10.11.5
Reaction time num false alarms AUC0.91.44.4-2.1-1.8-1.3-1.2-0.40.8-1.4-1.00.1-0.10.8
Reaction time trials correct on left0.20.51.4-1.2-0.9-0.5-1.20.1-0.4-0.10.30.4-0.4-0.8
Reaction time trials on left0.30.51.6-1.3-1.0-0.6-1.3-0.1-0.3-0.30.10.2-0.2-0.7
Reaction time mean3.75.88.3-2.7-2.7-2.9-2.5-2.72.2-2.3-2.3-2.42.41.1
Reaction time mean AUC3.45.47.6-2.5-2.6-2.8-2.5-2.62.0-2.2-2.1-2.42.41.0
Median of all reaction times3.95.57.9-2.7-2.7-2.8-2.6-2.62.0-2.3-2.1-2.32.31.0
Reaction time omissions3.14.55.8-2.1-2.1-2.4-1.6-2.22.3-2.2-2.4-2.02.01.8
Reaction time false alarm rate0.40.51.4-1.2-1.0-0.8-0.4-0.30.7-0.9-0.8-0.00.00.8
Reaction time premature initiation rate4.96.710.73.33.13.03.02.8-2.12.62.22.4-2.4-1.1
Reaction time premature initiations2.64.65.92.32.32.42.02.4-1.92.12.02.3-2.3-1.2
Std. dev. reaction times1.42.63.7-1.6-1.6-1.9-1.6-1.91.4-1.4-1.6-1.91.90.7
Reaction time trials completed0.30.51.6-1.3-1.0-0.6-1.3-0.1-0.3-0.30.10.2-0.2-0.7
Reaction time trials AUC0.30.62.0-1.4-1.1-0.8-1.4-0.2-0.1-0.4-0.00.1-0.1-0.5
Run reversals in cocaine runway, females3.73.77.1-0.8-1.1-1.9-0.9-2.32.7-1.7-2.1-2.32.32.0
Run reversals in cocaine runway, males0.70.81.7-1.1-1.2-0.8-1.3-0.70.5-1.0-0.8-0.60.60.4
Latency to leave start box in cocaine runway2.02.23.7-0.8-0.9-1.4-0.6-1.61.9-1.5-1.8-1.71.71.9
Latency to leave start box in cocaine runway, F1.71.92.7-0.9-1.1-1.5-1.0-1.61.6-1.3-1.4-1.61.61.1
Latency to leave start box in cocaine runway, M0.40.42.00.20.2-0.10.6-0.20.8-0.4-0.7-0.20.21.4
Std. dev. time between licks in bursts0.91.32.71.00.91.31.41.6-0.70.60.61.7-1.70.2
Total sessions with >9 infusions0.80.92.4-1.4-1.2-1.2-1.6-0.80.1-0.4-0.2-0.50.5-1.2
Short access day 1 total inactive lever presses0.40.62.00.0-0.2-1.0-0.2-0.91.4-0.4-0.7-0.90.9-0.1
Short access day 10 total inactive lever presses1.22.93.71.61.61.71.51.9-1.51.81.81.9-1.9-1.6
Short access day 1 total infusions1.01.42.9-1.5-1.3-1.6-1.7-1.10.4-0.4-0.1-0.80.8-1.7
Short access day 10 total infusions0.40.51.1-1.0-0.7-1.0-1.1-0.70.5-0.5-0.5-0.50.5-0.2
Short access total infusions0.70.81.7-1.2-1.0-1.3-1.3-0.90.7-0.7-0.6-0.70.7-0.4
Short access day 1 locomotion1.51.93.9-1.9-1.7-1.9-2.0-1.40.8-0.9-0.7-1.11.1-0.9
Short access day 10 total locomotion0.30.51.8-1.3-1.2-0.5-1.2-0.3-0.2-0.7-0.4-0.10.1-0.1
Short access total locomotion1.11.33.1-1.8-1.7-1.4-1.7-1.00.3-1.0-0.7-0.70.7-0.5
One hour access (0.3 mA shock)0.80.91.3-1.1-1.0-1.0-1.1-0.90.8-1.0-1.0-0.80.80.7
Compulsive drug intake1.01.22.70.20.40.90.11.1-1.61.01.31.1-1.1-1.6
One hour access (shock baseline)1.21.82.5-1.1-1.1-1.3-1.0-1.41.5-1.5-1.6-1.31.31.6
Social response proportion1.21.32.5-0.9-1.1-1.2-0.3-1.11.6-1.4-1.4-0.90.91.5
Social responses0.50.62.5-0.3-0.60.10.40.50.4-1.0-0.90.7-0.71.6
Social time0.91.22.10.60.71.10.71.4-1.40.91.11.5-1.5-0.9
Soleus weight0.10.31.0-0.4-0.5-0.3-0.2-0.20.6-0.8-0.6-0.10.11.0
Bone: stiffness0.50.82.10.40.4-0.50.4-0.91.5-0.4-0.9-1.21.21.2
Tibialis anterior weight0.10.41.0-0.9-1.0-0.9-0.6-0.50.6-0.6-0.5-0.30.30.1
Time to tail flick, vehicle, before self-admin0.30.30.60.80.70.80.70.7-0.40.40.20.6-0.60.0
Time to tail flick, vehicle, after self-admin0.30.41.50.80.50.70.90.50.2-0.2-0.50.4-0.41.2
Time to tail flick, test, before self-admin4.24.47.1-1.8-1.9-2.4-1.7-2.72.1-1.7-1.8-2.62.61.0
Time to tail flick, test, after self-admin0.00.00.20.1-0.10.00.2-0.10.2-0.2-0.2-0.10.10.4
Delta time to tail flick, vehicle, before/after SA0.00.00.20.2-0.0-0.00.2-0.10.4-0.1-0.2-0.10.10.4
Delta time to tail flick, test, before/after SA0.60.61.40.30.30.90.41.1-1.00.50.71.2-1.2-0.4
Tibia length0.20.41.30.80.80.20.1-0.1-0.31.10.8-0.40.4-1.1
Ambulatory time before self-admin1.11.72.6-1.5-1.3-1.6-1.6-1.60.9-1.0-1.0-1.41.40.0
Ambulatory time after self-admin0.20.30.6-0.6-0.3-0.5-0.7-0.70.1-0.4-0.3-0.80.8-0.0
Bone: tissue strength0.70.71.5-1.0-1.1-1.2-0.8-0.90.9-0.5-0.4-0.70.7-0.3
Total heroin consumption0.30.31.1-0.3-0.5-0.3-0.2-0.20.5-0.8-0.9-0.20.21.1
Bone: trabecular number6.010.016.23.13.53.72.13.0-4.03.53.52.4-2.4-2.8
Bone: trabecular spacing4.45.88.1-2.5-2.8-2.8-1.8-2.42.9-2.7-2.5-1.91.92.0
Bone: trabecular thickness0.60.82.11.11.51.10.80.6-1.01.10.90.3-0.3-0.5
Bone: trabecular tissue density3.55.27.6-1.6-2.0-2.3-1.8-2.72.4-2.3-2.4-2.82.81.9
Water consumed over 24 hours0.40.61.40.91.01.20.80.9-0.80.40.40.6-0.60.3
Number of responses in last shaping day0.70.73.8-0.6-0.4-0.1-0.80.5-0.80.50.80.9-0.9-1.9