Hub : Genes

MAST1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression MAST1 0.3 0.12 0.0e+00 0.23 0.22 0.23 0.23 3.6e-21 3.0e-20 1.1e-21 1.6e-21
2 PL gene expression MAST1 0.15 0.07 6.1e-12 0.1 0.11 0.1 0.1 6.8e-11 1.4e-11 1.5e-11 2.7e-11
3 BLA gene expression MAST1 0.13 0.07 1.5e-03 0.05 0.02 0.05 0.04 1.0e-03 4.8e-02 1.8e-03 2.5e-03
4 NAcc gene expression MAST1 0.12 0.06 1.8e-12 0.08 0.07 0.07 0.07 2.5e-12 1.9e-10 3.6e-11 2.1e-11
5 IC gene expression MAST1 0.39 0.15 1.2e-08 0.19 0.17 0.2 0.19 1.7e-08 1.2e-07 8.5e-09 3.1e-08
6 Brain mRNA stability MAST1 0.09 0.04 2.4e-06 0.06 0.07 0.07 0.07 1.4e-06 2.9e-07 8.1e-07 7.8e-07
7 IL gene expression MAST1 0.16 0.09 8.8e-03 0.05 0.06 0.06 0.04 2.3e-02 1.4e-02 1.3e-02 3.4e-02
8 OFC gene expression MAST1 0.47 0.15 1.1e-06 0.19 0.13 0.16 0.17 2.8e-05 5.7e-04 1.0e-04 9.0e-05
9 IC intron excision ratio chr19_40121006_40122784 0.09 0.06 6.0e-03 0.05 0.02 0 0.03 5.4e-03 6.7e-02 3.0e-01 2.0e-02
10 IC intron excision ratio chr19_40121353_40122784 0.09 0.06 4.4e-03 0.05 0.02 0 0.04 3.6e-03 5.1e-02 2.3e-01 1.1e-02
11 PL mRNA stability MAST1 0.06 0.03 6.6e-06 0.04 0.05 0.04 0.04 9.8e-05 5.4e-06 2.1e-05 1.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density3.25.99.4-2.73.0-3.1-2.2-2.5-2.7-2.5-2.3-2.12.1-1.3
Area under the delay curve0.10.20.90.20.0-0.50.3-0.5-0.9-0.2-0.4-0.50.5-0.5
BMI with tail1.55.310.12.9-3.22.62.21.92.02.82.31.4-1.41.9
BMI without tail0.00.10.30.5-0.6-0.00.2-0.4-0.40.30.0-0.50.50.1
Body weight0.20.72.20.6-0.71.0-0.30.61.50.70.90.3-0.31.1
Weight adjusted by age0.10.40.70.8-0.60.70.90.80.20.40.40.8-0.8-0.1
Bone surface3.67.19.8-2.73.0-2.8-2.4-2.6-2.7-3.1-3.0-2.22.2-2.4
Bone volume3.67.110.3-2.83.2-2.9-2.4-2.5-2.7-3.2-3.0-2.12.1-2.3
Breakpoint value in progressive ratio session0.81.44.6-0.0-0.30.7-0.30.91.91.31.70.9-0.92.1
Number of licking bursts0.10.40.8-0.30.1-0.6-0.8-0.8-0.10.30.3-0.90.90.9
Context. condit. distance diff. score1.41.73.31.7-1.81.61.10.91.51.61.40.5-0.51.1
Locomotion velocity, session 11.21.32.4-1.41.5-1.3-1.2-1.2-0.9-1.2-1.0-1.01.0-0.6
Locomotion distance, session 10.20.30.9-0.20.3-0.3-0.8-0.40.50.20.4-0.50.51.0
Locomotion velocity, session 20.60.71.3-0.90.8-1.1-0.8-1.1-0.7-0.5-0.5-1.11.10.1
Locomotion distance, session 20.50.82.70.5-0.50.6-0.40.41.41.11.10.2-0.21.6
Locomotion velocity, session 30.10.10.40.2-0.0-0.10.5-0.2-0.4-0.3-0.4-0.30.3-0.7
Locomotion distance, session 32.32.65.5-0.60.7-1.5-0.9-2.1-1.7-1.3-1.6-2.32.3-1.5
Stereotopy head waving bouts, day 30.50.52.60.6-0.50.31.10.1-0.9-0.5-0.7-0.10.1-1.6
Stereotopy head waving duration, day 30.20.31.10.7-0.70.51.00.3-0.30.20.00.2-0.2-0.5
Locomotion velocity, session 70.20.20.70.5-0.70.2-0.0-0.50.20.40.1-0.80.80.1
Locomotion distance, session 70.20.30.8-0.40.3-0.4-0.9-0.60.30.10.1-0.60.60.7
Stereotopy head waving bouts, day 70.91.02.5-0.20.3-0.80.1-1.0-1.6-0.9-1.2-1.11.1-1.5
Stereotopy head waving duration, day 71.31.53.4-0.80.8-1.2-0.4-1.3-1.8-1.2-1.4-1.31.3-1.4
Locomotion velocity, session 80.20.31.30.1-0.10.3-0.6-0.21.10.30.5-0.50.50.8
Locomotion distance, session 80.91.33.31.1-1.21.00.00.31.71.61.5-0.10.11.8
Degree of sensitization distance1.31.43.20.1-0.41.0-0.11.31.81.11.31.3-1.31.7
Degree of sensitization stereotypy0.50.61.4-0.20.1-0.6-0.2-0.8-1.2-0.6-0.8-0.90.9-1.0
Conditioned locomotion0.10.10.2-0.30.3-0.1-0.5-0.20.2-0.2-0.1-0.30.30.1
Cocaine response after cond. corrected0.81.33.00.6-0.91.10.20.91.71.31.50.8-0.81.5
Cocaine response after cond. not corrected0.91.23.10.6-0.81.00.20.81.71.31.50.7-0.71.8
Cocaine response before conditioning0.50.61.0-0.50.7-0.9-0.4-1.0-0.9-0.7-0.9-1.01.0-0.4
Saline control response1.11.65.0-1.51.1-1.2-2.2-1.20.50.10.4-1.01.01.8
Bone: connectivity density6.510.315.5-3.43.4-3.9-2.8-3.5-3.6-3.2-3.2-3.03.0-2.0
Bone: cortical apparent density0.20.30.80.3-0.8-0.30.6-0.4-0.90.4-0.1-0.50.5-0.2
Bone: cortical area0.10.20.5-0.10.20.1-0.6-0.20.70.00.2-0.40.40.5
Bone: cortical porosity1.21.32.41.2-1.01.50.81.31.61.01.21.1-1.10.7
Bone: cortical porosity0.60.61.71.0-0.81.20.40.81.30.60.80.6-0.60.3
Bone: cortical thickness1.21.93.11.6-1.71.71.01.11.81.71.50.7-0.71.4
Bone: cortical thickness2.32.810.81.0-1.20.80.50.91.72.52.40.8-0.83.3
Bone: cortical tissue density0.20.31.00.3-0.7-0.30.5-0.5-1.00.2-0.3-0.70.7-0.4
Condit. Reinf. active minus inactive responses0.70.82.41.6-1.40.70.6-0.5-0.10.3-0.2-1.21.2-0.6
Condit. Reinf. active-inactive response ratio1.01.12.91.6-1.71.20.60.21.01.20.9-0.40.40.7
Condit. Reinf. active responses0.60.71.80.8-0.6-0.00.2-0.9-0.8-0.4-0.9-1.41.4-1.0
Condit. Reinf. inactive responses2.63.45.1-1.82.0-2.0-1.4-1.8-2.0-2.1-2.3-1.61.6-1.7
Incentive salience index mean1.31.63.50.30.0-0.6-0.1-1.5-1.4-1.1-1.6-1.91.9-1.6
Condit. Reinf. lever presses2.43.56.7-0.91.4-1.6-0.5-1.9-2.3-2.3-2.6-1.91.9-2.4
Condit. Reinf. active minus inactive responses0.20.30.6-0.40.4-0.3-0.4-0.7-0.1-0.6-0.6-0.80.8-0.6
Condit. Reinf. active-inactive response ratio0.10.20.40.3-0.20.60.60.50.60.10.20.4-0.4-0.0
Condit. Reinf. active responses0.10.10.4-0.40.4-0.2-0.6-0.40.2-0.2-0.1-0.50.50.1
Condit. Reinf. inactive responses0.20.31.20.0-0.10.2-0.40.40.70.70.80.5-0.51.1
Condit. Reinf. lever presses0.00.00.00.1-0.1-0.00.10.0-0.10.1-0.00.1-0.1-0.1
Condit. Reinf. lever reinforcers received0.00.10.2-0.40.3-0.2-0.4-0.30.0-0.2-0.1-0.30.3-0.0
Conditioned reinforcement - actives0.00.00.00.10.10.20.1-0.00.2-0.00.1-0.10.10.0
Conditioned reinforcement - inactives0.00.00.10.2-0.20.20.3-0.10.20.00.1-0.20.2-0.3
Conditioned locomotion0.10.10.30.1-0.1-0.10.1-0.4-0.2-0.1-0.2-0.50.5-0.5
Patch foraging indifference point 0 sec0.10.30.60.2-0.20.2-0.4-0.50.1-0.5-0.5-0.80.8-0.8
Patch foraging indifference point AUC0.51.13.0-1.71.7-1.4-1.4-0.7-0.7-0.9-0.6-0.20.20.1
Delay disc. indifference point, 0s delay1.51.72.6-1.31.6-1.5-1.0-1.2-1.5-1.4-1.3-1.01.0-1.2
Delay disc. indifference point, 16s delay0.81.21.81.0-1.10.91.01.10.81.41.31.1-1.11.0
Delay disc. indifference point, 2s delay0.30.31.41.0-0.60.31.20.2-0.50.20.00.1-0.1-0.5
Delay disc. indifference point, 24s delay0.10.20.70.6-0.80.70.30.30.60.40.20.1-0.10.1
Delay disc. indifference point, 4s delay2.02.15.2-0.71.2-1.7-0.2-1.5-2.3-1.3-1.6-1.41.4-1.6
Delay disc. indifference point, 8s delay0.20.30.80.2-0.1-0.50.2-0.6-0.9-0.1-0.5-0.70.7-0.5
Indifference point function ln k0.30.92.91.7-1.61.11.40.4-0.00.4-0.0-0.10.1-1.0
Indifference point function log k0.30.92.91.7-1.61.11.40.4-0.00.4-0.0-0.10.1-1.0
Patch foraging total patch changes 0 sec0.10.20.40.6-0.60.6-0.0-0.00.5-0.1-0.1-0.40.4-0.5
Patch foraging total patch changes 12 sec1.01.43.1-1.01.0-1.1-1.8-1.5-0.3-0.9-0.7-1.61.60.1
Patch foraging total patch changes 18 sec1.33.06.4-2.02.1-1.9-2.5-1.9-0.8-1.5-1.2-1.81.8-0.1
Patch foraging total patch changes 24 sec0.72.33.6-1.81.6-1.5-1.9-1.6-1.0-1.6-1.5-1.41.4-0.9
Patch foraging total patch changes 6 sec0.30.51.0-0.80.8-0.9-1.0-0.8-0.4-0.6-0.5-0.70.70.1
Patch foraging time to switch 0 sec0.00.10.4-0.00.1-0.0-0.30.10.20.20.40.2-0.20.6
Patch foraging water rate 0 sec0.00.10.30.0-0.10.40.00.40.5-0.00.00.4-0.40.0
Patch foraging water rate 12 sec0.10.51.60.5-0.3-0.30.8-0.5-1.3-0.3-0.8-0.60.6-1.1
Patch foraging water rate 18 sec1.33.06.4-0.60.7-1.4-0.1-1.8-2.3-1.7-2.3-1.91.9-2.5
Patch foraging water rate 24 sec0.71.02.30.1-0.2-0.50.3-1.1-1.2-0.7-1.2-1.31.3-1.5
Patch foraging water rate 6 sec2.53.75.4-2.32.3-2.3-2.3-2.1-1.4-1.7-1.5-1.91.9-0.4
Seeking ratio, delayed vs. immediate footshock0.71.02.41.5-1.40.81.50.60.11.10.80.5-0.50.5
Distance traveled before self-admin0.41.01.81.2-1.11.21.31.20.50.70.61.1-1.1-0.2
Distance traveled after self-admin0.71.22.01.3-1.01.21.41.40.40.80.61.4-1.4-0.0
Extensor digitorum longus weight0.52.14.61.0-1.01.60.61.62.11.41.61.5-1.51.7
Bone: elastic displacement0.20.20.70.8-0.80.70.60.20.20.1-0.1-0.00.0-0.5
Bone: elastic work1.51.93.41.8-1.81.91.41.31.51.31.21.0-1.00.6
Bone: endosteal estimation0.10.41.3-0.50.8-0.3-1.1-0.30.6-0.00.4-0.30.30.9
Bone: endosteal perimeter0.51.22.9-1.01.3-0.8-1.7-1.20.1-1.1-0.7-1.41.4-0.2
Epididymis fat weight0.00.10.40.0-0.10.3-0.4-0.10.7-0.10.0-0.30.30.2
Delta time in closed arm before/after self-admin0.20.20.60.8-0.70.40.60.1-0.10.30.0-0.00.0-0.1
Delta time in open arm before/after self-admin0.91.03.8-1.71.4-0.7-2.0-0.20.8-0.50.20.1-0.11.0
Diff in mean of infusions in LGA sessions0.10.20.4-0.60.6-0.6-0.6-0.5-0.1-0.20.0-0.40.40.5
Delay discount exponential model param0.20.31.0-0.20.00.5-0.30.61.00.20.50.7-0.70.6
Extinction: sum of active levers before priming0.40.72.31.5-1.30.61.40.3-0.50.60.00.1-0.1-0.4
Active lever presses in extinction session 60.60.62.40.6-0.3-0.00.7-0.3-1.1-0.6-0.9-0.50.5-1.6
Bone: final force0.10.20.9-0.20.30.3-0.40.40.90.20.40.4-0.40.8
Bone: final moment0.10.21.0-0.00.10.4-0.20.41.00.30.50.4-0.40.8
Food consumed during 24 hour testing period2.14.39.0-2.82.8-2.7-3.0-2.2-1.0-1.4-1.0-1.71.70.8
Glucose0.30.51.4-0.1-0.10.7-0.41.01.20.20.51.1-1.10.4
Heart weight0.30.51.21.0-1.10.01.0-0.1-0.80.90.4-0.20.20.2
Delay discount hyperbolic model param0.40.51.5-0.2-0.10.7-0.30.81.20.30.60.9-0.90.7
Intermittent access intake day 1-15 change0.52.63.6-1.81.9-1.9-1.9-1.7-1.4-1.7-1.5-1.51.5-0.8
Intermittent access intake escalation0.31.62.2-1.31.4-1.5-1.5-1.4-1.2-1.3-1.2-1.31.3-0.5
Intermittent access intake escalation 21.22.02.8-1.51.5-1.6-1.7-1.5-1.3-1.4-1.3-1.31.3-0.6
Intermitt. access day 1 inactive lever presses0.11.23.7-0.70.9-0.7-0.4-0.9-1.1-1.3-1.3-1.01.0-1.9
Intermitt. access day 15 inactive lever presses0.10.81.21.0-0.91.11.10.81.10.80.90.6-0.60.3
Intermitt. access escalation Index0.10.20.60.3-0.4-0.30.4-0.4-0.8-0.1-0.4-0.50.5-0.6
Intermittent access day 1 total infusions0.82.53.91.9-1.71.92.01.61.41.61.51.4-1.40.6
Intermittent access day 15 total infusions0.20.40.91.0-0.80.80.90.60.40.60.60.4-0.40.0
Intermittent access terminal intake (last 3 days)0.30.50.90.9-0.70.91.00.70.60.50.60.6-0.6-0.1
Intermittent access total infusions0.91.11.81.2-1.11.31.31.11.01.01.10.9-0.90.3
Intermittent access day 1 locomotion0.61.12.51.5-1.41.11.60.80.61.00.90.6-0.60.1
Intermittent access day 15 total locomotion0.51.82.31.3-1.31.51.21.51.41.31.41.5-1.50.9
Intermittent access total locomotion2.12.53.41.6-1.61.71.51.51.71.81.81.4-1.41.2
Intermittent access standard deviation0.20.91.2-0.91.0-1.0-0.8-1.0-0.9-1.1-0.9-0.90.9-0.9
Left kidney weight0.43.26.9-2.11.7-1.8-2.6-2.2-0.6-1.3-1.2-2.12.10.3
Right kidney weight0.31.86.5-1.61.1-0.9-2.5-1.40.6-0.6-0.3-1.51.51.0
Cocaine induced anxiety0.10.41.50.5-0.20.10.6-0.5-0.6-0.4-0.7-0.70.7-1.2
Post-drug Anxiety0.10.20.50.7-0.60.50.70.30.10.40.20.1-0.1-0.1
Baseline Anxiety0.40.72.7-0.0-0.20.3-0.20.80.90.91.20.9-0.91.6
Tail length1.89.515.2-3.63.9-3.4-3.2-3.0-2.6-3.5-3.0-2.52.5-2.0
Length with tail0.52.25.2-2.12.3-1.3-2.3-1.0-0.4-1.9-1.2-0.80.8-0.7
Length without tail0.31.54.20.5-0.61.40.01.42.10.91.31.4-1.41.3
Times rat made contact with spout0.10.10.30.00.1-0.40.2-0.4-0.60.0-0.1-0.30.30.1
Lifetime Intake0.60.71.31.0-0.81.21.10.90.90.70.80.7-0.70.1
Liver weight, left0.30.62.1-1.01.0-0.4-1.4-0.4-0.1-1.0-0.6-0.30.3-0.7
Liver weight, right0.81.33.3-1.21.2-0.8-1.8-1.0-0.3-1.4-1.2-1.11.1-0.9
Locomotor activity0.91.43.50.8-0.60.90.31.11.41.41.61.1-1.11.9
Locomotor testing distance0.61.42.80.8-0.60.90.31.31.31.31.41.4-1.41.7
Locomotor testing rearing0.20.92.5-0.90.8-1.0-1.6-0.80.10.20.4-0.70.71.6
Locomotion in novel chamber0.70.93.70.6-0.70.50.40.41.11.31.40.3-0.31.9
Locomotion in novel chamber post-restriction0.30.81.2-1.00.9-0.8-0.7-0.7-0.8-1.1-1.0-0.60.6-1.1
Fecal boli incidents, locomotor time 10.41.12.3-1.31.3-0.6-1.5-0.9-0.1-1.4-1.0-0.90.9-0.7
Change in fecal boli incidents, locomotor task1.92.05.1-0.91.0-1.8-0.5-1.6-2.3-1.1-1.5-1.51.5-1.3
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.3-0.5-0.0-0.2-0.60.10.1-0.10.10.2
Bouts of movement, locomotor time 10.20.20.80.5-0.00.00.7-0.0-0.7-0.4-0.5-0.10.1-0.9
Total resting periods, locomotor time 10.30.41.20.9-0.30.21.10.0-0.8-0.3-0.6-0.10.1-1.1
Rest time, locomotor task time 10.30.41.41.2-0.81.01.00.40.30.10.00.1-0.1-0.5
Distance moved, locomotor task time 10.20.51.5-0.2-0.20.1-0.20.60.70.91.10.8-0.81.2
Vertical activity count, locomotor time 10.21.55.0-2.21.6-1.5-2.2-0.60.2-0.20.3-0.20.21.3
Time >=10cm from walls, locomotor time 20.41.12.60.6-0.50.91.11.50.60.70.91.6-1.60.2
Bouts of movement, locomotor time 20.10.20.80.6-0.4-0.20.80.0-0.90.2-0.30.0-0.0-0.4
Total resting periods, locomotor time 20.00.10.60.4-0.1-0.30.6-0.0-0.80.1-0.3-0.00.0-0.2
Rest time, locomotor task time 20.10.10.3-0.20.5-0.3-0.3-0.5-0.3-0.3-0.2-0.50.5-0.0
Distance moved, locomotor task time 22.12.83.91.4-1.61.71.42.01.61.71.72.0-2.01.1
Vertical activity count, locomotor time 20.30.72.2-1.10.6-0.3-1.20.11.00.40.90.3-0.31.5
Light reinforcement 12.611.827.9-4.94.4-3.8-5.3-3.5-1.2-2.8-2.0-3.03.00.4
Light reinforcement 22.76.016.4-4.03.6-2.6-4.0-1.9-0.6-2.3-1.5-1.31.30.2
Bone: marrow area0.20.41.2-0.50.8-0.3-1.1-0.30.60.00.4-0.30.31.0
Bone: maximum diameter0.10.20.60.20.00.2-0.5-0.40.4-0.4-0.2-0.80.8-0.4
Bone: maximum force0.10.31.2-0.10.00.5-0.20.61.10.20.50.6-0.60.6
Bone: maximum moment0.10.31.20.1-0.10.6-0.10.51.10.30.50.5-0.50.6
Mean time between licks in bursts0.10.51.7-0.1-0.1-0.5-0.7-1.1-0.4-0.0-0.3-1.31.30.1
Mean num. licks in bursts0.10.41.30.30.00.11.00.5-0.7-0.5-0.60.6-0.6-1.1
Cd content in liver3.03.37.22.4-2.72.11.21.21.82.42.00.6-0.61.6
Co content in liver1.41.75.02.2-2.21.81.51.00.51.00.50.5-0.5-0.6
Cu content in liver0.60.71.50.9-1.11.10.20.51.21.00.90.2-0.20.9
Fe content in liver1.72.06.9-0.91.3-0.9-0.1-0.5-1.7-2.1-2.1-0.30.3-2.6
K content in liver0.50.50.80.7-0.80.90.80.90.60.40.40.9-0.9-0.1
Mg content in liver0.10.10.50.3-0.40.60.30.40.2-0.2-0.20.3-0.3-0.7
Mn content in liver0.20.30.9-0.40.1-0.1-0.9-0.60.4-0.0-0.0-0.70.70.4
Na content in liver0.20.20.5-0.60.7-0.5-0.10.1-0.4-0.7-0.50.4-0.4-0.6
Rb content in liver0.40.51.0-0.80.5-0.7-0.9-0.9-0.3-0.5-0.6-1.01.0-0.2
Se content in liver1.11.44.2-0.91.3-0.4-0.7-0.4-0.6-2.0-1.7-0.30.3-2.1
Sr content in liver1.00.91.81.1-1.31.30.50.81.20.90.80.6-0.60.6
Zn content in liver1.11.32.41.4-1.51.51.01.01.31.31.20.7-0.70.7
Bone: minimum diameter0.61.12.9-1.21.6-1.0-1.7-1.1-0.1-0.9-0.5-1.01.00.2
Time in familiar zone, hab. session 11.11.22.7-0.80.5-1.2-0.9-1.5-1.1-0.5-0.7-1.61.6-0.3
Time in novel zone, hab. session 11.11.22.81.0-0.70.91.41.50.30.70.61.7-1.70.1
Total zone transitions, hab. session 10.10.10.5-0.40.6-0.4-0.5-0.00.10.00.20.2-0.20.7
Total locomotion distance, hab. session 10.00.10.3-0.10.3-0.2-0.20.10.20.10.20.2-0.20.6
Locomotion velocity, hab. session 10.10.10.5-0.30.5-0.2-0.6-0.00.40.00.20.1-0.10.7
Time in familiar zone, hab. session 21.21.42.3-1.41.1-1.3-1.5-1.4-0.7-0.9-0.9-1.41.4-0.2
Time in novel zone, hab. session 23.43.74.62.1-2.12.01.82.01.62.12.01.9-1.91.4
Total zone transitions, hab. session 20.60.81.4-0.80.9-1.1-1.1-1.2-0.6-0.5-0.5-1.21.20.3
Total locomotion distance, hab. session 20.20.20.9-0.40.4-0.2-0.9-0.20.50.10.2-0.10.10.8
Locomotion velocity, hab. session 20.20.20.8-0.50.5-0.2-0.9-0.10.5-0.00.2-0.00.00.8
Novel to familiar place preference ratio0.60.81.51.0-1.00.71.00.80.61.21.10.8-0.81.0
Novelty place preference0.81.01.80.9-0.90.71.00.90.71.31.30.9-0.91.2
Time in novel zone, NPP test0.91.11.61.1-1.00.81.21.00.51.31.21.1-1.10.9
Total zone transitions, NPP test0.40.61.9-0.80.8-0.6-1.4-0.90.3-0.5-0.3-0.90.90.5
Total locomotion distance, NPP test0.10.10.2-0.10.2-0.1-0.4-0.30.20.00.0-0.40.40.4
Locomotion velocity, NPP test0.10.20.6-0.10.20.1-0.6-0.20.80.10.2-0.40.40.7
Intraocular pressure1.11.94.11.8-2.01.61.81.40.71.30.91.2-1.20.1
Delta distance traveled before/after self-admin0.10.10.2-0.30.4-0.4-0.2-0.1-0.3-0.2-0.2-0.00.00.1
Delta ambulatory time before/after self-admin0.50.81.4-0.90.9-1.2-0.8-1.0-1.0-0.8-0.9-0.90.9-0.3
Parametrial fat weight0.20.41.9-0.70.40.1-1.40.30.9-0.00.30.4-0.40.9
Pavlov. Cond. lever latency0.30.31.7-0.2-0.2-0.2-0.5-0.10.40.90.8-0.10.11.3
Pavlov. Cond. magazine entry latency0.30.41.50.7-0.30.31.10.4-0.6-0.4-0.60.4-0.4-1.2
Pavlov. Cond. change in total contacts1.01.13.1-0.40.8-0.6-0.2-0.8-1.0-1.5-1.5-0.80.8-1.7
Pavlov. Cond. index score0.40.52.10.7-0.30.50.90.3-0.4-0.6-0.70.2-0.2-1.4
Pavlov. Cond. latency score0.20.31.40.5-0.20.40.70.2-0.3-0.6-0.60.1-0.1-1.2
Pavlov. Cond. lever contacts0.40.52.10.5-0.00.40.90.3-0.4-0.8-0.80.3-0.3-1.5
Pavlov. Cond. magazine entry number0.70.92.4-1.10.8-0.9-1.5-0.90.30.20.4-0.90.91.4
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.30.2-0.0-0.9-0.5-0.0-0.8-0.8-0.70.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.72.01.0-0.60.91.30.8-0.1-0.4-0.50.7-0.7-1.4
Pavlov. Cond. response bias0.70.83.80.7-0.20.41.30.4-1.0-0.8-1.00.4-0.4-2.0
Pavlov. Cond. lever latency0.30.40.70.5-0.60.80.40.70.80.60.60.6-0.60.4
Pavlov. Cond. magazine entry latency0.00.00.20.2-0.0-0.00.0-0.3-0.00.10.0-0.40.40.1
Pavlov. Cond. change in total contacts0.30.61.4-0.40.4-0.8-0.2-0.9-1.2-0.7-0.9-0.90.9-1.0
Pavlov. Cond. index score0.20.40.7-0.40.4-0.7-0.2-0.7-0.9-0.6-0.7-0.60.6-0.6
Pavlov. Cond. latency score0.30.40.8-0.40.5-0.7-0.2-0.7-0.9-0.7-0.8-0.70.7-0.7
Pavlov. Cond. lever contacts0.30.40.8-0.60.6-0.9-0.5-0.8-0.8-0.4-0.5-0.70.7-0.2
Pavlov. Cond. magazine entry number0.00.00.10.2-0.20.10.20.20.20.30.20.2-0.20.3
Pavlov. Cond. intertrial magazine entries0.91.93.9-1.71.7-1.6-2.0-1.5-0.8-1.2-1.0-1.41.4-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.30.3-0.6-0.1-0.6-0.8-0.5-0.6-0.60.6-0.6
Pavlov. Cond. response bias0.10.10.2-0.30.2-0.4-0.2-0.4-0.3-0.2-0.2-0.30.3-0.1
Time in closed arm before self-admin1.22.22.9-1.01.2-1.4-0.7-1.7-1.7-1.5-1.6-1.71.7-1.6
Time in closed arm after self-admin1.01.12.4-0.20.4-0.8-0.2-1.4-1.2-0.8-1.1-1.51.5-1.1
Time in open arm before self-admin0.50.61.21.1-1.00.71.00.80.20.90.60.8-0.80.4
Time in open arm after self-admin0.60.71.20.3-0.50.70.21.01.10.81.01.1-1.11.0
Bone: periosteal estimation0.20.51.7-0.60.8-0.4-1.3-0.60.7-0.10.3-0.70.70.9
Bone: periosteal perimeter0.40.92.3-0.50.5-0.4-1.5-1.20.4-0.5-0.3-1.51.50.1
Bone: post-yield work0.10.20.8-0.70.9-0.4-0.5-0.00.0-0.30.00.2-0.20.5
Progressive ratio test 1 active lever presses0.71.32.01.2-1.11.41.31.11.31.11.20.9-0.90.5
Progressive ratio test 1 breakpoint0.81.42.21.2-1.21.51.41.21.31.21.31.0-1.00.5
Progressive ratio test 1 inactive lever presses0.10.40.90.6-0.51.00.80.50.80.40.50.2-0.2-0.5
Progressive ratio test 2 active lever presses1.01.42.01.3-1.21.41.31.21.21.21.21.1-1.10.7
Progressive ratio test 2 breakpoint1.21.62.21.4-1.21.51.41.31.21.31.31.2-1.20.7
Progressive ratio test 2 inactive lever presses0.72.13.21.8-1.71.71.81.41.31.51.41.2-1.20.6
Incentive Sensitization - Responses0.20.40.90.5-0.50.60.50.80.50.60.60.9-0.90.6
Incentive Sensitization - Breakpoint0.20.30.80.4-0.40.50.40.70.40.50.50.9-0.90.5
Sum of active levers in priming session hrs 5-60.20.21.1-0.1-0.1-0.1-0.20.10.30.50.60.2-0.21.0
Progressive ratio0.10.31.2-0.80.4-0.4-1.0-0.30.40.10.3-0.10.11.1
Food seeking constrained by brief footshock1.62.04.0-1.61.5-1.2-2.0-1.5-0.6-1.4-1.4-1.51.5-0.7
Seeking ratio, punishment vs. effort0.20.51.3-0.60.7-0.3-0.7-0.5-0.4-1.1-1.0-0.60.6-1.2
Retroperitoneal fat weight0.20.83.6-0.0-0.10.8-1.20.31.90.50.80.0-0.01.6
Reaction time number correct0.10.51.41.2-0.90.51.2-0.1-0.40.1-0.3-0.40.4-0.8
Reaction time mean minus median0.21.52.41.1-1.21.51.11.51.10.91.21.5-1.50.3
Reaction time mean minus median AUC0.42.74.41.7-1.72.11.62.01.51.31.41.9-1.90.3
Reaction time num false alarms1.32.24.92.2-2.11.71.10.71.61.81.60.1-0.11.5
Reaction time num false alarms AUC0.61.44.42.1-1.81.31.20.40.81.41.0-0.10.10.8
Reaction time trials correct on left0.10.51.41.2-0.90.51.2-0.1-0.40.1-0.3-0.40.4-0.8
Reaction time trials on left0.10.51.61.3-1.00.61.30.1-0.30.3-0.1-0.20.2-0.7
Reaction time mean2.65.88.32.7-2.72.92.52.72.22.32.32.4-2.41.1
Reaction time mean AUC2.25.47.62.5-2.62.82.52.62.02.22.12.4-2.41.0
Median of all reaction times3.55.57.92.7-2.72.82.62.62.02.32.12.3-2.31.0
Reaction time omissions2.84.55.82.1-2.12.41.62.22.32.22.42.0-2.01.8
Reaction time false alarm rate0.40.51.41.2-1.00.80.40.30.70.90.80.0-0.00.8
Reaction time premature initiation rate4.36.710.7-3.33.1-3.0-3.0-2.8-2.1-2.6-2.2-2.42.4-1.1
Reaction time premature initiations1.54.65.9-2.32.3-2.4-2.0-2.4-1.9-2.1-2.0-2.32.3-1.2
Std. dev. reaction times0.82.63.71.6-1.61.91.61.91.41.41.61.9-1.90.7
Reaction time trials completed0.10.51.61.3-1.00.61.30.1-0.30.3-0.1-0.20.2-0.7
Reaction time trials AUC0.20.62.01.4-1.10.81.40.2-0.10.40.0-0.10.1-0.5
Run reversals in cocaine runway, females3.33.77.10.8-1.11.90.92.32.71.72.12.3-2.32.0
Run reversals in cocaine runway, males0.70.81.71.1-1.20.81.30.70.51.00.80.6-0.60.4
Latency to leave start box in cocaine runway1.62.23.70.8-0.91.40.61.61.91.51.81.7-1.71.9
Latency to leave start box in cocaine runway, F1.51.92.70.9-1.11.51.01.61.61.31.41.6-1.61.1
Latency to leave start box in cocaine runway, M0.40.42.0-0.20.20.1-0.60.20.80.40.70.2-0.21.4
Std. dev. time between licks in bursts0.71.32.7-1.00.9-1.3-1.4-1.6-0.7-0.6-0.6-1.71.70.2
Total sessions with >9 infusions0.70.92.41.4-1.21.21.60.80.10.40.20.5-0.5-1.2
Short access day 1 total inactive lever presses0.30.62.0-0.0-0.21.00.20.91.40.40.70.9-0.9-0.1
Short access day 10 total inactive lever presses0.42.93.7-1.61.6-1.7-1.5-1.9-1.5-1.8-1.8-1.91.9-1.6
Short access day 1 total infusions0.71.42.91.5-1.31.61.71.10.40.40.10.8-0.8-1.7
Short access day 10 total infusions0.30.51.11.0-0.71.01.10.70.50.50.50.5-0.5-0.2
Short access total infusions0.60.81.71.2-1.01.31.30.90.70.70.60.7-0.7-0.4
Short access day 1 locomotion1.11.93.91.9-1.71.92.01.40.80.90.71.1-1.1-0.9
Short access day 10 total locomotion0.10.51.81.3-1.20.51.20.3-0.20.70.40.1-0.1-0.1
Short access total locomotion0.91.33.11.8-1.71.41.71.00.31.00.70.7-0.7-0.5
One hour access (0.3 mA shock)0.70.91.31.1-1.01.01.10.90.81.01.00.8-0.80.7
Compulsive drug intake0.81.22.7-0.20.4-0.9-0.1-1.1-1.6-1.0-1.3-1.11.1-1.6
One hour access (shock baseline)0.71.82.51.1-1.11.31.01.41.51.51.61.3-1.31.6
Social response proportion1.11.32.50.9-1.11.20.31.11.61.41.40.9-0.91.5
Social responses0.50.62.50.3-0.6-0.1-0.4-0.50.41.00.9-0.70.71.6
Social time0.81.22.1-0.60.7-1.1-0.7-1.4-1.4-0.9-1.1-1.51.5-0.9
Soleus weight0.10.31.00.4-0.50.30.20.20.60.80.60.1-0.11.0
Bone: stiffness0.40.82.1-0.40.40.5-0.40.91.50.40.91.2-1.21.2
Tibialis anterior weight0.10.41.00.9-1.00.90.60.50.60.60.50.3-0.30.1
Time to tail flick, vehicle, before self-admin0.30.30.6-0.80.7-0.8-0.7-0.7-0.4-0.4-0.2-0.60.60.0
Time to tail flick, vehicle, after self-admin0.20.41.5-0.80.5-0.7-0.9-0.50.20.20.5-0.40.41.2
Time to tail flick, test, before self-admin3.84.47.11.8-1.92.41.72.72.11.71.82.6-2.61.0
Time to tail flick, test, after self-admin0.00.00.2-0.1-0.1-0.0-0.20.10.20.20.20.1-0.10.4
Delta time to tail flick, vehicle, before/after SA0.00.00.2-0.2-0.00.0-0.20.10.40.10.20.1-0.10.4
Delta time to tail flick, test, before/after SA0.50.61.4-0.30.3-0.9-0.4-1.1-1.0-0.5-0.7-1.21.2-0.4
Tibia length0.20.41.3-0.80.8-0.2-0.10.1-0.3-1.1-0.80.4-0.4-1.1
Ambulatory time before self-admin0.51.72.61.5-1.31.61.61.60.91.01.01.4-1.40.0
Ambulatory time after self-admin0.20.30.60.6-0.30.50.70.70.10.40.30.8-0.8-0.0
Bone: tissue strength0.60.71.51.0-1.11.20.80.90.90.50.40.7-0.7-0.3
Total heroin consumption0.30.31.10.3-0.50.30.20.20.50.80.90.2-0.21.1
Bone: trabecular number5.310.016.2-3.13.5-3.7-2.1-3.0-4.0-3.5-3.5-2.42.4-2.8
Bone: trabecular spacing4.05.88.12.5-2.82.81.82.42.92.72.51.9-1.92.0
Bone: trabecular thickness0.60.82.1-1.11.5-1.1-0.8-0.6-1.0-1.1-0.9-0.30.3-0.5
Bone: trabecular tissue density3.05.27.61.6-2.02.31.82.72.42.32.42.8-2.81.9
Water consumed over 24 hours0.30.61.4-0.91.0-1.2-0.8-0.9-0.8-0.4-0.4-0.60.60.3
Number of responses in last shaping day0.60.73.80.6-0.40.10.8-0.5-0.8-0.5-0.8-0.90.9-1.9