Hub : Genes

Lsm10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Lsm10 0.12 0.07 3.7e-03 -0 0.02 0 -0 9.5e-01 4.4e-03 1.2e-01 7.4e-01
2 pVTA alternative TSS NM_001108976.1 0.06 0.04 1.7e-03 0.01 0.02 0.02 0.02 2.4e-02 6.7e-03 1.1e-02 1.1e-02
3 pVTA isoform ratio XM_006238897.4 0.08 0.05 1.1e-06 0.08 0.09 0.08 0.07 5.5e-07 1.9e-07 1.1e-06 1.3e-06
4 pVTA alternative TSS XM_063288119.1 0.03 0.02 1.1e-03 0.02 0.03 0.03 0.03 4.6e-03 8.4e-04 2.1e-03 4.1e-03
5 pVTA isoform ratio XM_063288119.1 0.03 0.02 7.0e-04 0.04 0.04 0.03 0.03 7.4e-04 2.9e-04 2.9e-03 2.4e-03
6 pVTA alternative TSS XM_006238897.4 0.09 0.05 7.7e-07 0.05 0.08 0.08 0.07 4.4e-05 2.8e-07 6.9e-07 2.8e-06
7 Adipose alternative TSS XM_006238897.4 0.37 0.12 0.0e+00 0.13 0.14 0.14 0.14 7.9e-14 9.6e-16 7.6e-16 1.0e-15
8 Adipose alternative TSS XM_006238897.4 0.4 0.12 0.0e+00 0.14 0.16 0.16 0.16 1.8e-15 1.2e-17 6.6e-17 1.5e-17
9 pVTA alternative TSS XM_006238897.4 0.11 0.06 5.7e-07 0.05 0.09 0.08 0.07 4.6e-05 2.0e-07 8.5e-07 2.9e-06
10 LHb alternative TSS XM_063288119.1 0.18 0.14 5.3e-03 0.09 0.08 0.07 0.03 4.6e-03 6.7e-03 1.0e-02 5.3e-02
11 Brain mRNA stability Lsm10 0.06 0.04 2.9e-03 0.02 0.02 0.02 0.02 6.2e-03 2.8e-03 9.9e-03 6.1e-03
12 Adipose isoform ratio XM_006238897.4 0.45 0.12 0.0e+00 0.16 0.18 0.18 0.18 3.2e-17 5.4e-20 3.3e-19 2.2e-19
13 PL alternative TSS XM_006238897.4 0.06 0.04 2.2e-03 0.01 0.01 0.01 0.01 4.3e-02 1.5e-02 2.3e-02 2.9e-02
14 Liver alternative TSS XM_006238897.4 0.36 0.1 0.0e+00 0.21 0.21 0.21 0.21 2.9e-23 2.1e-23 3.2e-23 3.5e-23
15 Liver alternative TSS XM_006238897.4 0.38 0.11 0.0e+00 0.18 0.2 0.2 0.2 1.4e-19 2.0e-21 1.4e-21 1.8e-21
16 PL isoform ratio XM_006238897.4 0.07 0.06 5.1e-03 0.02 0.01 0.01 0.01 5.0e-03 4.9e-02 5.2e-02 1.3e-02
17 Brain alternative TSS XM_006238897.4 0.05 0.03 3.1e-04 0.04 0.04 0.04 0.04 4.4e-05 7.4e-05 2.4e-04 2.2e-04
18 Brain isoform ratio XM_006238897.4 0.05 0.03 1.4e-03 0.04 0.03 0.03 0.03 1.7e-04 6.3e-04 6.8e-04 7.3e-04
19 PL mRNA stability Lsm10 0.04 0.04 9.2e-03 0.02 0.01 0.01 0.01 2.9e-03 6.1e-02 2.8e-02 1.7e-02
20 PL alternative TSS XM_006238897.4 0.06 0.06 4.9e-03 0.02 0.01 0.01 0.01 3.1e-03 4.6e-02 4.7e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.01.85.5-2.4-1.41.7-1.6-1.61.6-1.21.11.51.5-0.91.10.91.2-1.1-0.8-1.2-1.21.0-0.8
Area under the delay curve0.10.20.8-0.90.3-0.2-0.2-0.3-0.20.8-0.6-0.3-0.40.6-0.5-0.3-0.2-0.10.20.10.1-0.10.1
BMI with tail0.41.47.8-2.80.8-1.00.90.9-0.90.9-0.9-0.9-0.40.6-0.9-0.7-0.91.11.31.11.1-1.41.8
BMI without tail0.84.26.3-1.62.1-1.91.41.4-2.02.3-2.2-2.1-1.92.0-2.2-2.1-2.02.22.12.12.1-2.32.5
Body weight0.42.026.2-5.1-0.71.2-1.9-1.91.10.2-0.00.81.00.3-0.0-0.30.3-0.4-0.4-0.4-0.40.10.3
Weight adjusted by age0.20.61.70.20.8-0.3-0.2-0.3-0.40.9-1.0-0.6-1.31.3-1.0-1.0-0.90.90.90.70.7-0.60.8
Bone surface0.81.610.0-3.2-1.11.6-1.9-1.91.5-0.80.61.31.1-0.20.60.30.7-0.7-0.4-0.9-0.90.8-0.4
Bone volume1.53.020.2-4.5-1.61.9-1.9-1.91.8-1.21.11.71.5-0.91.11.01.4-1.4-0.9-1.6-1.61.4-1.0
Breakpoint value in progressive ratio session0.10.21.11.1-0.4-0.10.50.60.1-0.70.60.20.3-0.70.50.60.3-0.10.10.20.2-0.00.2
Number of licking bursts0.20.70.9-0.6-0.90.9-0.8-0.80.9-0.80.80.90.7-0.70.80.80.9-0.9-0.9-0.7-0.70.8-0.9
Context. condit. distance diff. score0.50.61.30.10.8-1.11.21.2-1.10.6-0.7-1.0-0.60.3-0.7-0.4-0.60.70.70.70.7-0.70.7
Locomotion velocity, session 10.20.20.30.40.5-0.40.20.2-0.40.4-0.5-0.5-0.40.5-0.5-0.5-0.50.50.50.50.5-0.30.4
Locomotion distance, session 10.00.00.10.00.0-0.10.10.1-0.10.0-0.0-0.10.2-0.0-0.0-0.1-0.10.10.20.30.3-0.10.3
Locomotion velocity, session 20.10.11.61.30.20.0-0.1-0.1-0.00.2-0.1-0.0-0.40.3-0.1-0.2-0.1-0.0-0.2-0.1-0.10.1-0.2
Locomotion distance, session 20.00.00.10.40.00.0-0.1-0.10.00.1-0.1-0.00.00.2-0.1-0.2-0.20.20.30.40.4-0.30.2
Locomotion velocity, session 33.23.65.31.42.0-2.12.02.0-2.11.9-1.8-2.0-1.71.6-1.8-1.7-1.91.91.91.91.9-2.12.3
Locomotion distance, session 30.10.20.50.70.3-0.50.60.6-0.40.2-0.2-0.4-0.10.1-0.2-0.2-0.30.30.50.50.5-0.40.6
Stereotopy head waving bouts, day 31.21.51.81.31.2-1.10.90.8-1.11.3-1.2-1.2-0.91.3-1.2-1.3-1.31.41.31.31.3-1.31.3
Stereotopy head waving duration, day 32.93.64.40.72.1-1.91.61.5-2.02.1-2.1-2.0-1.81.9-2.1-2.0-2.02.02.01.91.9-1.91.8
Locomotion velocity, session 72.62.83.8-0.41.9-1.71.21.2-1.81.8-2.0-1.9-1.71.7-1.9-1.8-1.81.81.81.81.8-1.41.6
Locomotion distance, session 70.20.21.5-1.2-0.20.00.10.10.0-0.40.20.10.2-0.50.20.50.5-0.5-0.3-0.4-0.40.9-0.8
Stereotopy head waving bouts, day 70.30.43.31.80.20.1-0.4-0.40.10.4-0.2-0.0-0.00.6-0.3-0.6-0.60.50.50.50.5-0.90.7
Stereotopy head waving duration, day 70.20.21.01.00.20.1-0.3-0.40.10.5-0.3-0.1-0.10.6-0.3-0.6-0.50.40.50.40.4-0.70.5
Locomotion velocity, session 80.10.10.10.10.3-0.1-0.0-0.1-0.20.2-0.3-0.2-0.40.4-0.3-0.4-0.30.30.30.30.3-0.30.4
Locomotion distance, session 81.11.62.30.11.3-1.41.11.1-1.41.3-1.3-1.4-1.11.1-1.3-1.2-1.31.41.41.51.5-1.41.3
Degree of sensitization distance0.50.53.2-1.8-0.40.6-0.8-0.90.6-0.40.20.50.2-0.30.20.30.6-0.5-0.6-0.6-0.61.0-1.1
Degree of sensitization stereotypy0.20.32.71.6-0.30.6-0.7-0.70.6-0.20.30.50.40.10.3-0.1-0.1-0.10.00.00.0-0.30.2
Conditioned locomotion5.56.511.61.8-2.61.7-0.3-0.11.9-3.13.22.33.0-3.43.23.22.8-2.8-2.7-2.4-2.42.5-2.5
Cocaine response after cond. corrected0.20.40.6-0.3-0.70.7-0.6-0.60.7-0.60.70.70.5-0.60.70.60.6-0.6-0.7-0.6-0.60.4-0.3
Cocaine response after cond. not corrected0.20.33.0-1.7-0.40.4-0.4-0.40.4-0.30.30.40.2-0.30.30.30.4-0.4-0.4-0.4-0.40.4-0.3
Cocaine response before conditioning0.80.96.4-2.51.0-0.90.70.6-0.90.9-1.2-0.9-0.90.8-1.1-0.8-0.60.70.90.50.5-0.20.1
Saline control response0.10.10.3-0.10.3-0.10.10.1-0.20.3-0.3-0.20.00.4-0.3-0.5-0.50.30.60.50.5-0.40.5
Bone: connectivity density0.71.12.4-1.6-1.21.3-1.2-1.21.3-1.01.01.31.3-0.71.00.70.9-0.8-0.6-0.9-0.90.7-0.4
Bone: cortical apparent density0.20.41.0-0.30.8-0.91.01.0-0.90.6-0.7-0.8-0.90.3-0.6-0.3-0.30.40.30.30.3-0.40.1
Bone: cortical area0.40.71.60.50.50.1-0.7-0.7-0.00.8-0.8-0.3-0.51.3-0.8-1.2-1.01.01.01.01.0-1.01.0
Bone: cortical porosity1.51.62.21.2-1.31.5-1.4-1.41.5-1.41.31.41.0-0.91.31.01.1-1.1-1.3-1.2-1.21.4-1.4
Bone: cortical porosity1.11.21.91.3-1.01.3-1.2-1.21.2-1.11.11.20.7-0.71.00.80.9-0.9-1.1-1.1-1.11.3-1.4
Bone: cortical thickness0.30.41.41.20.6-0.50.50.5-0.60.6-0.5-0.6-0.40.6-0.6-0.6-0.70.70.80.70.7-0.80.8
Bone: cortical thickness0.30.41.71.30.5-0.81.21.2-0.70.2-0.2-0.6-0.30.0-0.2-0.1-0.40.30.30.30.3-0.40.7
Bone: cortical tissue density0.30.41.2-0.30.8-1.01.11.1-1.00.6-0.7-0.9-0.90.3-0.7-0.3-0.30.40.30.30.3-0.40.1
Condit. Reinf. active minus inactive responses0.70.813.0-3.6-0.40.3-0.2-0.10.3-0.50.20.30.5-0.50.20.40.5-0.4-0.1-0.3-0.30.8-0.6
Condit. Reinf. active-inactive response ratio0.80.914.1-3.8-0.40.00.20.20.0-0.40.30.20.6-0.80.30.60.6-0.4-0.2-0.4-0.40.7-0.6
Condit. Reinf. active responses0.30.45.1-2.3-0.40.3-0.1-0.10.3-0.50.30.30.6-0.50.30.40.4-0.20.0-0.1-0.10.6-0.4
Condit. Reinf. inactive responses0.00.00.50.7-0.10.00.20.20.0-0.20.20.10.1-0.10.20.20.1-0.10.00.00.00.00.1
Incentive salience index mean1.01.321.7-4.7-0.60.6-0.5-0.50.5-0.50.30.50.8-0.40.20.30.5-0.40.1-0.2-0.20.7-0.5
Condit. Reinf. lever presses0.81.223.4-4.8-0.10.3-0.3-0.40.2-0.0-0.20.10.40.1-0.2-0.1-0.00.10.50.20.20.20.0
Condit. Reinf. active minus inactive responses0.10.10.5-0.70.4-0.20.10.1-0.30.4-0.4-0.3-0.60.4-0.4-0.3-0.30.00.10.20.20.00.3
Condit. Reinf. active-inactive response ratio0.30.53.3-1.8-0.60.7-0.7-0.70.7-0.40.40.60.2-0.30.40.40.5-0.7-0.5-0.6-0.60.7-0.4
Condit. Reinf. active responses0.91.32.5-0.91.3-1.10.70.7-1.11.3-1.4-1.2-1.61.3-1.4-1.2-1.10.91.01.01.0-0.71.0
Condit. Reinf. inactive responses2.03.04.5-0.22.0-2.12.01.9-2.11.8-1.9-2.1-1.81.5-1.9-1.5-1.61.61.71.61.6-1.41.5
Condit. Reinf. lever presses1.01.57.2-2.7-1.00.7-0.3-0.30.8-1.00.90.90.5-1.10.91.31.3-1.4-1.3-1.4-1.41.4-1.3
Condit. Reinf. lever reinforcers received1.11.52.7-1.31.4-1.31.00.9-1.31.4-1.5-1.4-1.71.3-1.5-1.2-1.10.91.11.01.0-0.71.0
Conditioned reinforcement - actives0.20.91.5-0.1-1.20.9-0.5-0.41.0-1.11.21.01.2-1.21.21.11.0-1.0-0.8-0.7-0.70.6-0.9
Conditioned reinforcement - inactives0.30.81.10.2-1.01.0-0.8-0.71.0-1.01.11.00.9-0.91.10.91.0-1.0-0.9-0.9-0.90.7-0.8
Conditioned locomotion0.81.12.01.20.9-0.80.70.6-0.80.9-0.8-0.9-1.41.0-0.9-1.0-1.11.21.31.41.4-1.31.2
Patch foraging indifference point 0 sec0.41.06.0-2.5-0.81.0-1.1-1.10.8-0.50.60.81.1-0.60.60.40.8-1.0-1.0-0.9-0.91.1-0.9
Patch foraging indifference point AUC2.76.58.3-2.5-2.62.3-1.7-1.72.4-2.52.52.52.4-2.52.52.72.9-2.8-2.9-2.8-2.82.8-2.7
Delay disc. indifference point, 0s delay0.40.41.7-1.3-0.50.8-1.3-1.30.70.10.10.60.50.10.10.10.3-0.6-0.2-0.2-0.20.4-0.7
Delay disc. indifference point, 16s delay0.50.71.7-1.30.8-0.4-0.4-0.5-0.51.2-1.2-0.6-1.31.3-1.1-1.0-0.80.50.50.40.4-0.50.7
Delay disc. indifference point, 2s delay0.70.81.9-0.21.0-1.00.60.5-1.01.4-1.2-1.0-1.01.0-1.1-0.8-0.80.70.70.80.8-0.80.7
Delay disc. indifference point, 24s delay0.10.22.0-1.40.1-0.1-0.1-0.2-0.10.3-0.2-0.1-0.20.0-0.20.10.2-0.6-0.5-0.5-0.50.4-0.3
Delay disc. indifference point, 4s delay1.51.62.30.61.3-1.41.31.3-1.41.5-1.3-1.4-1.11.0-1.2-0.9-1.21.01.31.31.3-1.31.3
Delay disc. indifference point, 8s delay0.00.00.10.3-0.10.1-0.1-0.10.10.20.00.10.30.00.00.0-0.0-0.20.10.10.1-0.10.0
Indifference point function ln k2.37.18.8-1.62.9-2.72.02.0-2.82.9-3.0-2.9-2.72.6-3.0-2.8-2.82.82.82.62.6-2.62.7
Indifference point function log k2.37.18.8-1.62.9-2.72.02.0-2.82.9-3.0-2.9-2.72.6-3.0-2.8-2.82.82.82.62.6-2.62.7
Patch foraging total patch changes 0 sec0.20.66.4-2.5-0.50.6-0.8-0.80.5-0.20.20.50.8-0.30.20.10.5-0.7-0.6-0.6-0.60.7-0.5
Patch foraging total patch changes 12 sec2.83.75.8-1.2-1.81.9-1.9-1.91.8-1.51.61.91.8-1.51.61.62.0-2.2-2.4-2.3-2.32.4-2.4
Patch foraging total patch changes 18 sec3.48.010.5-2.6-3.12.6-1.9-1.82.7-2.83.02.93.2-3.03.03.03.1-3.1-2.9-2.9-2.92.8-2.5
Patch foraging total patch changes 24 sec0.72.43.9-2.0-1.61.4-1.0-1.01.4-1.51.61.51.9-1.61.61.51.7-1.8-1.5-1.5-1.51.4-1.3
Patch foraging total patch changes 6 sec1.42.43.8-0.9-1.81.7-1.5-1.41.7-1.51.61.81.9-1.41.61.41.5-1.6-1.5-1.3-1.31.5-1.4
Patch foraging time to switch 0 sec0.10.34.42.1-0.20.4-0.4-0.40.4-0.20.30.30.10.10.2-0.1-0.10.10.20.20.2-0.20.1
Patch foraging water rate 0 sec0.10.52.1-1.40.7-0.50.10.0-0.60.9-0.9-0.6-0.70.8-0.8-0.8-0.60.60.60.60.6-0.50.7
Patch foraging water rate 12 sec0.41.82.4-0.51.4-1.30.80.8-1.31.5-1.5-1.4-1.41.4-1.5-1.5-1.41.51.41.41.4-1.51.4
Patch foraging water rate 18 sec0.71.52.7-1.21.4-1.41.11.1-1.41.3-1.4-1.4-1.61.1-1.4-1.1-1.01.11.31.01.0-0.70.8
Patch foraging water rate 24 sec0.30.51.4-0.00.7-1.11.21.2-1.00.6-0.6-0.9-0.70.2-0.5-0.3-0.40.40.50.50.5-0.60.6
Patch foraging water rate 6 sec2.03.04.2-0.12.0-1.91.61.5-1.91.9-1.9-2.0-2.01.7-1.9-1.6-1.71.71.51.51.5-1.61.7
Seeking ratio, delayed vs. immediate footshock0.10.20.8-0.9-0.2-0.30.70.7-0.2-0.40.4-0.00.3-0.70.40.70.4-0.2-0.2-0.2-0.20.40.5
Distance traveled before self-admin0.40.93.61.90.7-0.1-0.6-0.6-0.10.9-0.8-0.3-1.31.5-0.9-1.1-1.00.90.70.80.8-0.90.9
Distance traveled after self-admin0.20.41.51.20.7-0.60.30.3-0.60.7-0.7-0.6-1.00.8-0.7-0.5-0.60.60.30.50.5-0.40.3
Extensor digitorum longus weight1.66.413.9-3.7-2.82.1-1.1-1.02.3-2.82.72.53.1-3.02.72.82.8-2.6-2.0-2.3-2.32.4-2.2
Bone: elastic displacement0.10.20.40.10.5-0.60.60.5-0.60.5-0.4-0.6-0.40.2-0.4-0.2-0.30.30.10.30.3-0.3-0.0
Bone: elastic work0.50.71.5-1.2-0.80.6-0.2-0.10.6-0.90.80.71.0-1.00.80.90.9-0.9-0.8-0.9-0.91.0-1.2
Bone: endosteal estimation0.30.83.1-1.30.10.8-1.7-1.80.60.6-0.70.2-0.41.3-0.7-1.2-0.70.60.50.50.5-0.40.6
Bone: endosteal perimeter0.20.52.9-1.0-0.10.9-1.7-1.70.70.3-0.30.40.10.9-0.4-0.8-0.40.40.40.40.4-0.30.2
Epididymis fat weight0.10.72.10.10.5-0.30.10.0-0.30.8-0.6-0.5-0.40.9-0.7-0.9-1.01.11.21.11.1-1.31.5
Delta time in closed arm before/after self-admin2.01.92.8-1.3-1.51.7-1.7-1.61.7-1.31.41.60.8-1.01.31.21.3-1.4-1.4-1.3-1.31.2-1.4
Delta time in open arm before/after self-admin4.24.97.3-0.32.5-2.62.32.2-2.72.4-2.4-2.7-1.81.8-2.4-2.2-2.22.32.12.12.1-2.02.1
Diff in mean of infusions in LGA sessions1.52.83.80.71.7-1.51.01.0-1.61.7-1.8-1.7-1.81.7-1.8-1.8-1.81.91.92.02.0-1.81.7
Delay discount exponential model param0.20.31.00.5-0.60.5-0.2-0.20.6-1.00.80.60.6-0.70.70.50.4-0.1-0.4-0.3-0.30.4-0.3
Extinction: sum of active levers before priming1.01.52.81.4-1.30.9-0.2-0.11.0-1.41.51.21.0-1.41.51.71.4-1.3-1.3-1.2-1.21.2-1.2
Active lever presses in extinction session 60.40.41.51.2-0.70.4-0.00.00.5-0.90.90.60.5-0.80.90.90.6-0.5-0.5-0.4-0.40.4-0.3
Bone: final force0.71.12.90.60.70.1-1.0-1.0-0.01.0-1.1-0.4-0.81.7-1.1-1.6-1.31.31.41.21.2-1.11.0
Bone: final moment1.01.54.00.70.90.0-1.0-1.1-0.11.3-1.3-0.5-1.12.0-1.4-1.8-1.51.41.51.31.3-1.31.2
Food consumed during 24 hour testing period0.40.71.7-0.0-0.80.10.50.50.3-0.91.00.50.6-1.31.01.31.1-1.0-1.1-0.9-0.90.9-0.7
Glucose1.93.124.24.91.5-1.61.51.5-1.51.2-1.1-1.5-1.31.2-1.1-1.0-1.51.71.31.61.6-1.51.3
Heart weight0.71.21.8-0.8-1.31.2-1.0-1.01.2-1.11.21.21.4-1.11.21.01.0-1.0-1.0-1.1-1.10.7-0.7
Delay discount hyperbolic model param0.30.41.10.2-0.70.6-0.3-0.20.6-1.10.80.60.7-0.80.80.50.5-0.3-0.5-0.5-0.50.5-0.4
Intermittent access intake day 1-15 change0.10.53.9-2.0-0.1-0.20.40.4-0.20.10.1-0.10.4-0.70.20.50.6-0.8-1.0-0.9-0.90.6-0.7
Intermittent access intake escalation0.10.65.3-2.3-0.2-0.00.20.2-0.1-0.00.20.10.4-0.70.30.50.7-0.9-1.0-0.9-0.90.7-0.9
Intermittent access intake escalation 20.40.63.6-1.90.0-0.30.60.6-0.4-0.00.0-0.2-0.1-0.70.20.60.7-0.8-1.1-1.0-1.00.9-1.1
Intermitt. access day 1 inactive lever presses0.00.51.41.20.5-0.91.21.2-0.80.3-0.3-0.70.1-0.0-0.3-0.1-0.40.40.80.70.7-0.70.4
Intermitt. access day 15 inactive lever presses0.31.73.3-1.0-1.20.60.00.10.7-1.31.30.91.1-1.71.41.71.7-1.5-1.5-1.5-1.51.6-1.8
Intermitt. access escalation Index0.92.83.9-2.0-1.71.9-2.0-1.91.9-1.31.51.81.5-1.21.51.31.6-1.6-1.9-1.8-1.81.5-1.1
Intermittent access day 1 total infusions0.10.30.80.90.3-0.50.80.8-0.4-0.0-0.0-0.4-0.2-0.0-0.1-0.2-0.40.50.80.80.8-0.70.6
Intermittent access day 15 total infusions0.10.31.1-1.1-0.3-0.00.40.5-0.0-0.40.50.10.4-0.80.50.60.5-0.5-0.6-0.5-0.50.3-0.4
Intermittent access terminal intake (last 3 days)0.10.20.9-0.9-0.2-0.10.30.4-0.0-0.30.30.1-0.1-0.60.30.40.4-0.4-0.5-0.5-0.50.4-0.4
Intermittent access total infusions0.10.10.2-0.10.2-0.30.40.4-0.30.2-0.1-0.3-0.40.1-0.1-0.2-0.30.30.40.40.4-0.50.4
Intermittent access day 1 locomotion0.20.41.10.50.4-0.30.30.3-0.30.3-0.3-0.4-0.30.4-0.4-0.6-0.70.71.00.90.9-1.00.9
Intermittent access day 15 total locomotion0.00.10.2-0.3-0.20.10.00.00.1-0.10.20.1-0.2-0.30.30.20.3-0.4-0.4-0.4-0.40.20.2
Intermittent access total locomotion0.20.20.50.70.3-0.30.30.3-0.30.3-0.2-0.3-0.70.3-0.3-0.4-0.50.40.70.70.7-0.60.5
Intermittent access standard deviation0.31.33.11.01.1-1.51.71.8-1.40.8-0.8-1.3-1.00.4-0.8-0.8-1.01.11.11.11.1-1.31.1
Left kidney weight0.11.213.3-3.6-0.80.8-0.9-0.90.7-0.40.50.71.0-0.60.50.50.8-0.8-0.6-0.7-0.70.6-0.7
Right kidney weight0.11.08.4-2.9-0.71.0-1.5-1.50.9-0.20.30.80.4-0.20.40.20.5-0.7-0.7-0.8-0.80.5-0.6
Cocaine induced anxiety0.71.83.9-2.01.3-0.8-0.0-0.1-1.01.7-1.6-1.2-0.91.6-1.6-1.7-1.51.21.41.51.5-1.41.1
Post-drug Anxiety0.30.42.1-1.40.4-0.2-0.2-0.3-0.30.6-0.6-0.40.00.6-0.6-0.7-0.60.40.70.70.7-0.70.2
Baseline Anxiety1.22.03.61.5-1.51.2-0.5-0.41.3-1.91.81.41.3-1.61.71.71.5-1.4-1.1-1.3-1.31.3-1.4
Tail length0.10.83.2-1.80.40.5-1.5-1.60.31.0-1.0-0.0-0.81.4-0.9-1.2-0.60.30.00.10.1-0.20.1
Length with tail0.73.312.1-3.5-1.42.3-3.1-3.12.0-0.60.71.81.6-0.10.70.31.1-1.5-1.6-1.6-1.61.5-1.5
Length without tail0.84.110.3-1.8-2.12.8-3.2-3.22.6-1.41.62.42.2-0.81.50.91.5-1.8-2.0-1.7-1.71.7-1.5
Times rat made contact with spout0.10.10.40.40.2-0.40.70.7-0.40.1-0.0-0.3-0.1-0.2-0.00.1-0.10.00.10.20.2-0.20.2
Lifetime Intake0.00.00.1-0.1-0.1-0.00.30.3-0.0-0.20.30.0-0.1-0.40.30.20.1-0.1-0.0-0.0-0.0-0.1-0.0
Liver weight, left1.01.817.3-4.2-1.11.4-1.6-1.61.3-0.60.61.21.1-0.40.60.50.9-1.0-0.5-0.9-0.90.8-0.5
Liver weight, right0.50.95.0-2.2-0.90.9-0.8-0.80.8-0.50.70.81.3-0.70.70.60.8-1.2-0.8-0.9-0.90.7-0.4
Locomotor activity3.14.810.93.32.2-1.61.00.9-1.72.0-2.2-1.9-2.52.5-2.2-2.4-2.42.42.42.42.4-2.01.8
Locomotor testing distance1.53.815.13.91.9-1.50.90.9-1.51.6-1.8-1.6-2.32.1-1.8-1.9-2.02.22.02.02.0-1.61.4
Locomotor testing rearing0.51.925.35.01.0-1.01.21.2-1.00.4-0.6-0.9-1.20.6-0.6-0.5-0.81.00.70.80.8-0.40.3
Locomotion in novel chamber1.41.95.70.71.5-2.12.42.4-1.91.0-1.2-1.7-1.50.6-1.1-0.6-1.01.20.91.01.0-1.10.9
Locomotion in novel chamber post-restriction0.20.73.6-1.90.6-0.3-0.4-0.5-0.40.9-1.0-0.5-0.71.1-1.0-1.0-0.80.80.80.90.9-0.80.5
Fecal boli incidents, locomotor time 10.00.00.1-0.30.1-0.10.10.1-0.1-0.1-0.0-0.1-0.1-0.1-0.00.10.1-0.0-0.2-0.2-0.20.4-0.4
Change in fecal boli incidents, locomotor task0.20.21.1-0.1-0.40.6-0.6-0.60.5-0.30.40.50.5-0.20.40.30.4-0.4-0.4-0.3-0.30.4-1.0
Time >=10cm from walls, locomotor time 10.40.42.9-0.4-0.21.0-1.7-1.70.80.2-0.10.50.10.7-0.2-0.6-0.2-0.10.0-0.1-0.10.1-0.4
Bouts of movement, locomotor time 11.62.15.92.41.5-1.71.91.8-1.61.3-1.1-1.5-1.51.0-1.1-0.9-1.21.11.11.31.3-1.41.5
Total resting periods, locomotor time 12.22.67.52.71.5-1.92.12.1-1.81.2-1.1-1.6-1.50.9-1.1-0.9-1.31.31.41.51.5-1.51.6
Rest time, locomotor task time 12.64.18.62.12.2-2.72.92.9-2.61.7-1.7-2.4-1.81.1-1.7-1.3-1.71.91.71.81.8-1.71.7
Distance moved, locomotor task time 10.10.31.3-0.6-0.50.8-1.1-1.10.7-0.20.20.60.10.10.20.20.3-0.5-0.4-0.5-0.50.5-0.5
Vertical activity count, locomotor time 10.10.52.5-1.6-0.41.0-1.5-1.60.80.1-0.00.60.70.4-0.0-0.40.0-0.4-0.00.00.00.0-0.1
Time >=10cm from walls, locomotor time 20.41.13.3-1.5-1.01.5-1.8-1.81.4-0.60.71.21.1-0.30.70.30.6-0.8-0.7-0.8-0.80.6-0.3
Bouts of movement, locomotor time 20.20.62.01.10.7-0.70.50.5-0.60.7-0.6-0.6-1.40.8-0.6-0.6-0.80.90.70.70.7-0.80.9
Total resting periods, locomotor time 20.10.51.50.80.7-0.60.50.5-0.60.6-0.5-0.6-1.20.7-0.6-0.6-0.70.80.70.70.7-0.80.9
Rest time, locomotor task time 21.22.04.70.71.6-2.02.22.2-1.91.2-1.3-1.8-1.50.8-1.3-0.9-1.21.31.11.21.2-1.00.9
Distance moved, locomotor task time 20.10.20.9-0.9-0.40.4-0.4-0.40.4-0.20.30.40.7-0.30.30.30.3-0.4-0.4-0.4-0.40.2-0.1
Vertical activity count, locomotor time 20.20.42.6-1.6-0.50.8-1.2-1.20.70.10.10.61.00.10.1-0.20.1-0.4-0.4-0.2-0.20.1-0.0
Light reinforcement 10.20.82.0-1.4-0.60.10.40.40.2-0.70.70.50.4-1.10.81.11.1-1.1-1.3-1.3-1.31.1-0.9
Light reinforcement 20.10.31.3-1.10.4-0.81.11.1-0.70.3-0.3-0.5-0.3-0.1-0.20.10.00.10.1-0.1-0.1-0.20.3
Bone: marrow area0.30.83.1-1.20.20.7-1.7-1.80.60.6-0.70.2-0.41.4-0.7-1.2-0.70.60.60.60.6-0.50.6
Bone: maximum diameter0.51.02.7-0.50.40.5-1.6-1.60.40.9-0.9-0.0-0.51.6-1.0-1.5-1.11.00.90.90.9-0.91.0
Bone: maximum force0.61.12.90.50.80.0-0.9-1.0-0.11.1-1.1-0.4-0.81.7-1.2-1.6-1.31.21.31.11.1-1.11.1
Bone: maximum moment0.81.53.90.60.9-0.0-0.9-1.0-0.21.3-1.3-0.6-1.12.0-1.4-1.8-1.51.41.41.21.2-1.31.2
Mean time between licks in bursts0.31.83.51.21.5-1.81.91.9-1.81.3-1.3-1.6-1.30.8-1.3-0.9-1.11.10.91.01.0-1.00.9
Mean num. licks in bursts0.41.02.40.91.0-1.31.51.5-1.30.8-0.8-1.2-0.60.5-0.8-0.6-0.80.91.00.80.8-0.90.9
Cd content in liver1.92.211.8-3.41.2-2.12.62.6-2.00.8-1.0-1.6-0.9-0.1-1.0-0.1-0.30.70.90.60.6-0.20.4
Co content in liver0.20.21.00.6-0.00.3-0.6-0.70.2-0.1-0.00.2-0.40.2-0.0-0.00.1-0.2-0.5-0.3-0.30.7-1.0
Cu content in liver4.14.98.60.2-2.52.9-2.8-2.82.9-2.42.32.72.3-1.52.21.71.9-1.9-1.8-1.7-1.71.9-2.2
Fe content in liver0.40.42.40.4-0.51.1-1.5-1.61.0-0.10.30.80.40.40.2-0.3-0.0-0.1-0.1-0.1-0.1-0.20.1
K content in liver0.20.20.70.7-0.30.6-0.8-0.80.5-0.30.10.4-0.00.10.10.00.3-0.3-0.3-0.3-0.30.5-0.5
Mg content in liver1.11.28.02.8-0.80.40.20.20.4-1.21.10.60.8-1.31.11.20.9-0.8-1.1-0.8-0.81.0-1.3
Mn content in liver5.05.610.53.2-2.41.9-1.0-0.92.0-2.82.82.22.3-2.72.82.72.4-2.4-2.6-2.2-2.22.2-2.6
Na content in liver0.80.92.00.10.7-0.1-0.6-0.6-0.31.1-1.0-0.5-0.81.4-1.0-1.3-1.21.21.11.11.1-1.31.2
Rb content in liver0.70.810.83.30.20.5-1.1-1.20.40.2-0.20.2-0.60.9-0.3-0.6-0.50.2-0.10.30.30.1-0.4
Se content in liver4.45.29.43.1-2.41.9-1.0-0.92.0-2.52.72.22.3-2.52.72.52.4-2.2-2.4-2.2-2.22.1-2.4
Sr content in liver3.63.260.8-7.8-0.0-0.20.30.3-0.20.1-0.4-0.10.2-0.3-0.30.20.6-0.50.4-0.5-0.50.5-0.0
Zn content in liver1.11.32.00.3-1.20.9-0.3-0.20.9-1.41.21.11.4-1.41.31.41.4-1.3-1.1-1.2-1.21.4-1.3
Bone: minimum diameter0.10.20.7-0.60.20.3-0.8-0.80.20.4-0.50.0-0.40.8-0.5-0.7-0.40.40.50.40.4-0.10.0
Time in familiar zone, hab. session 10.20.21.4-0.1-0.40.8-1.1-1.20.7-0.10.10.50.20.30.1-0.20.0-0.1-0.1-0.1-0.10.0-0.1
Time in novel zone, hab. session 10.20.20.60.80.0-0.20.60.6-0.2-0.20.2-0.1-0.0-0.40.20.40.4-0.3-0.5-0.4-0.40.6-0.4
Total zone transitions, hab. session 10.10.10.20.20.1-0.30.40.4-0.30.1-0.1-0.20.2-0.0-0.1-0.1-0.20.30.40.40.4-0.50.3
Total locomotion distance, hab. session 10.30.40.8-0.10.6-0.70.60.6-0.70.7-0.6-0.7-0.50.5-0.6-0.6-0.70.80.60.70.7-0.90.8
Locomotion velocity, hab. session 10.30.41.0-0.20.5-0.60.50.5-0.60.7-0.5-0.6-0.30.5-0.5-0.6-0.70.80.70.70.7-1.00.9
Time in familiar zone, hab. session 20.60.61.6-0.90.8-0.4-0.3-0.3-0.51.0-1.0-0.6-1.31.2-1.0-1.0-0.80.70.60.60.6-0.60.8
Time in novel zone, hab. session 20.40.42.51.6-0.40.20.40.40.2-0.70.70.40.8-0.80.70.70.6-0.5-0.5-0.5-0.50.6-0.8
Total zone transitions, hab. session 21.82.22.90.41.6-1.61.51.5-1.71.5-1.5-1.6-1.01.2-1.5-1.4-1.61.61.61.71.7-1.71.7
Total locomotion distance, hab. session 21.11.52.20.31.2-1.41.41.4-1.41.1-1.1-1.3-0.60.8-1.1-1.0-1.21.31.31.31.3-1.41.5
Locomotion velocity, hab. session 20.81.11.80.41.0-1.21.41.4-1.20.9-0.8-1.1-0.40.6-0.8-0.8-1.01.11.11.11.1-1.31.4
Novel to familiar place preference ratio1.11.42.90.81.2-1.51.71.7-1.51.1-1.0-1.4-0.80.6-1.0-0.8-1.01.11.21.21.2-1.21.1
Novelty place preference1.31.74.41.11.3-1.82.12.1-1.71.1-1.0-1.5-0.90.5-1.0-0.7-1.01.11.21.21.2-1.21.0
Time in novel zone, NPP test1.41.74.01.31.4-1.72.02.0-1.71.2-1.1-1.5-0.90.7-1.1-0.8-1.11.11.21.21.2-1.21.1
Total zone transitions, NPP test0.60.81.70.20.7-0.4-0.0-0.1-0.50.9-0.9-0.7-0.61.1-0.9-1.2-1.11.11.11.21.2-1.21.3
Total locomotion distance, NPP test0.30.41.00.40.5-0.40.10.1-0.40.6-0.6-0.5-0.30.7-0.6-0.8-0.80.80.80.80.8-0.91.0
Locomotion velocity, NPP test0.10.20.6-0.20.2-0.1-0.2-0.2-0.10.4-0.3-0.2-0.00.4-0.3-0.5-0.50.60.60.60.6-0.70.8
Intraocular pressure1.11.83.5-1.5-1.20.60.30.40.7-1.31.30.91.7-1.91.41.71.6-1.5-1.4-1.5-1.51.6-1.3
Delta distance traveled before/after self-admin0.40.42.9-1.7-0.40.10.10.10.1-0.40.40.20.7-0.80.40.60.7-0.6-0.7-0.7-0.70.7-0.7
Delta ambulatory time before/after self-admin0.30.51.7-1.3-0.70.30.00.10.3-0.70.70.51.0-1.00.70.80.8-0.7-0.7-0.7-0.70.6-0.6
Parametrial fat weight0.20.41.00.60.6-0.70.60.6-0.60.5-0.6-0.6-1.00.6-0.6-0.5-0.50.70.50.50.5-0.70.9
Pavlov. Cond. lever latency0.50.611.03.3-0.10.4-0.7-0.70.3-0.00.10.2-0.30.30.1-0.10.0-0.1-0.3-0.1-0.10.0-0.2
Pavlov. Cond. magazine entry latency0.30.46.9-2.6-0.30.20.00.00.2-0.40.20.20.6-0.40.20.30.3-0.30.0-0.2-0.20.4-0.1
Pavlov. Cond. change in total contacts0.70.79.4-3.10.5-0.81.11.1-0.80.3-0.5-0.6-0.0-0.0-0.5-0.1-0.20.20.50.20.2-0.00.2
Pavlov. Cond. index score0.50.610.0-3.2-0.30.10.20.20.1-0.40.20.20.6-0.50.20.40.3-0.30.1-0.2-0.20.3-0.1
Pavlov. Cond. latency score0.40.48.0-2.8-0.1-0.20.50.5-0.1-0.10.0-0.10.4-0.30.00.20.1-0.00.30.10.10.00.1
Pavlov. Cond. lever contacts0.80.913.5-3.7-0.50.10.40.50.1-0.60.50.30.9-0.90.50.80.6-0.5-0.2-0.5-0.50.6-0.4
Pavlov. Cond. magazine entry number0.20.23.51.9-0.10.3-0.5-0.50.30.00.10.2-0.20.20.1-0.1-0.00.0-0.2-0.1-0.1-0.1-0.1
Pavlov. Cond. intertrial magazine entries1.41.76.62.61.4-1.51.51.5-1.61.2-1.2-1.5-1.20.9-1.2-0.9-1.11.20.81.01.0-0.80.5
Pavlov. Cond. lever-magazine prob. diff.0.70.911.1-3.3-0.70.4-0.00.00.5-0.70.60.51.0-0.80.60.70.6-0.6-0.2-0.4-0.40.5-0.3
Pavlov. Cond. response bias0.50.711.6-3.4-0.2-0.10.50.5-0.1-0.30.20.00.4-0.50.20.40.3-0.3-0.0-0.3-0.30.4-0.1
Pavlov. Cond. lever latency0.20.31.51.2-0.00.3-0.7-0.70.20.1-0.10.10.30.4-0.1-0.5-0.50.50.40.60.6-0.60.5
Pavlov. Cond. magazine entry latency0.50.71.7-1.3-0.60.7-0.7-0.70.7-0.70.50.70.1-0.60.60.70.8-0.9-0.9-1.0-1.01.1-1.2
Pavlov. Cond. change in total contacts0.41.03.0-0.11.2-1.51.71.7-1.41.0-1.0-1.3-1.20.5-0.9-0.5-0.60.60.60.60.6-0.70.7
Pavlov. Cond. index score0.20.31.9-1.4-0.1-0.10.30.3-0.0-0.20.10.1-0.2-0.40.20.50.6-0.6-0.5-0.7-0.70.8-0.9
Pavlov. Cond. latency score0.60.92.0-1.4-0.60.4-0.0-0.00.5-0.80.70.60.3-1.00.71.11.1-1.1-1.1-1.3-1.31.4-1.4
Pavlov. Cond. lever contacts0.20.21.6-1.20.0-0.20.50.5-0.2-0.10.0-0.1-0.4-0.30.10.40.5-0.5-0.5-0.6-0.60.6-0.6
Pavlov. Cond. magazine entry number0.10.22.21.5-0.0-0.10.20.2-0.1-0.00.1-0.10.5-0.00.1-0.1-0.20.30.40.40.4-0.50.5
Pavlov. Cond. intertrial magazine entries0.10.30.90.40.6-0.71.00.9-0.70.4-0.5-0.7-0.20.3-0.5-0.3-0.40.30.50.40.4-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.20.31.9-1.40.0-0.20.50.5-0.2-0.10.0-0.1-0.3-0.40.10.40.5-0.5-0.4-0.6-0.60.7-0.7
Pavlov. Cond. response bias0.20.22.0-1.40.4-0.50.60.6-0.50.3-0.3-0.4-0.70.0-0.30.10.1-0.2-0.2-0.3-0.30.3-0.2
Time in closed arm before self-admin0.00.00.20.3-0.20.3-0.4-0.40.3-0.30.20.2-0.10.10.10.00.00.10.1-0.0-0.00.10.1
Time in closed arm after self-admin1.61.92.9-1.1-1.61.2-0.8-0.71.4-1.71.61.41.0-1.61.61.71.5-1.4-1.2-1.3-1.31.2-1.2
Time in open arm before self-admin0.00.00.20.4-0.20.2-0.0-0.00.2-0.20.30.20.4-0.20.30.30.2-0.4-0.2-0.1-0.1-0.1-0.2
Time in open arm after self-admin4.85.37.20.12.6-2.62.12.1-2.72.6-2.6-2.7-1.92.1-2.6-2.3-2.42.32.22.32.3-2.12.1
Bone: periosteal estimation0.40.92.5-0.20.30.6-1.5-1.60.40.8-0.80.0-0.51.6-0.9-1.4-1.00.90.90.90.9-0.81.0
Bone: periosteal perimeter0.61.12.8-1.10.50.4-1.4-1.50.21.0-1.0-0.1-0.51.7-1.1-1.5-1.11.01.11.11.1-0.90.9
Bone: post-yield work0.30.57.52.70.20.2-0.6-0.60.20.3-0.20.0-0.30.7-0.2-0.6-0.50.50.20.30.3-0.40.3
Progressive ratio test 1 active lever presses0.10.10.2-0.5-0.50.5-0.4-0.40.5-0.50.50.40.4-0.40.50.20.3-0.3-0.1-0.1-0.1-0.1-0.3
Progressive ratio test 1 breakpoint0.00.10.2-0.4-0.40.3-0.2-0.20.3-0.40.40.30.3-0.30.40.10.2-0.10.0-0.0-0.0-0.2-0.2
Progressive ratio test 1 inactive lever presses0.10.20.90.40.0-0.40.91.0-0.4-0.20.3-0.20.2-0.60.30.30.1-0.20.50.30.3-0.2-0.3
Progressive ratio test 2 active lever presses0.00.00.20.4-0.10.2-0.2-0.20.2-0.10.20.2-0.3-0.00.20.00.0-0.0-0.1-0.1-0.1-0.2-0.2
Progressive ratio test 2 breakpoint0.00.00.10.4-0.20.2-0.2-0.20.3-0.20.30.2-0.2-0.10.20.10.1-0.1-0.2-0.2-0.2-0.1-0.4
Progressive ratio test 2 inactive lever presses0.00.00.10.4-0.1-0.10.30.3-0.1-0.20.20.00.1-0.30.20.20.2-0.1-0.1-0.1-0.1-0.0-0.4
Incentive Sensitization - Responses0.10.30.60.3-0.50.7-0.7-0.70.7-0.30.40.6-0.2-0.20.40.30.4-0.4-0.7-0.7-0.70.3-0.6
Incentive Sensitization - Breakpoint0.10.20.50.4-0.30.5-0.6-0.60.5-0.20.30.5-0.3-0.10.30.20.3-0.3-0.7-0.6-0.60.3-0.5
Sum of active levers in priming session hrs 5-64.84.56.50.2-2.42.1-1.5-1.42.2-2.52.42.32.0-2.22.42.42.3-2.2-2.1-2.0-2.02.4-2.4
Progressive ratio0.30.82.21.5-0.80.8-0.5-0.50.8-1.00.90.90.3-0.70.90.90.9-0.7-1.2-1.2-1.21.2-0.6
Food seeking constrained by brief footshock1.41.73.3-0.7-1.21.5-1.7-1.71.5-0.91.01.40.7-0.71.00.81.2-1.2-1.8-1.7-1.71.3-1.4
Seeking ratio, punishment vs. effort0.10.33.4-1.80.20.1-0.6-0.6-0.00.7-0.5-0.10.10.6-0.5-0.6-0.40.20.30.30.3-0.60.0
Retroperitoneal fat weight0.00.20.70.2-0.40.7-0.8-0.80.6-0.00.30.50.60.10.3-0.10.0-0.0-0.10.00.0-0.60.7
Reaction time number correct0.41.210.2-3.21.0-0.70.0-0.0-0.81.4-1.3-0.9-0.91.2-1.3-1.1-0.80.60.80.50.5-0.60.8
Reaction time mean minus median0.00.10.50.50.0-0.30.70.7-0.2-0.00.2-0.10.1-0.30.20.30.00.0-0.1-0.1-0.1-0.30.1
Reaction time mean minus median AUC0.00.10.70.5-0.0-0.40.80.9-0.3-0.20.2-0.10.3-0.50.20.40.1-0.0-0.0-0.1-0.1-0.2-0.1
Reaction time num false alarms0.20.43.9-2.0-0.3-0.00.40.40.0-0.30.30.20.4-0.60.30.70.6-0.5-0.0-0.6-0.60.6-0.5
Reaction time num false alarms AUC0.20.57.5-2.7-0.30.2-0.0-0.00.2-0.20.10.30.2-0.30.20.50.5-0.50.1-0.5-0.50.7-0.6
Reaction time trials correct on left0.41.210.2-3.21.0-0.70.0-0.0-0.81.4-1.3-0.9-0.91.2-1.3-1.1-0.80.60.80.50.5-0.60.8
Reaction time trials on left0.41.210.6-3.31.0-0.60.0-0.1-0.81.4-1.3-0.8-0.91.1-1.2-1.1-0.70.60.80.40.4-0.60.7
Reaction time mean0.10.24.52.10.00.00.10.20.1-0.20.20.1-0.40.10.20.1-0.10.2-0.10.00.0-0.1-0.1
Reaction time mean AUC0.10.33.51.9-0.40.4-0.1-0.10.5-0.60.60.5-0.0-0.30.60.40.3-0.3-0.5-0.4-0.40.3-0.4
Median of all reaction times0.30.47.52.7-0.00.2-0.1-0.10.2-0.30.30.2-0.40.10.20.0-0.10.2-0.20.00.00.0-0.2
Reaction time omissions0.00.00.10.4-0.0-0.10.30.4-0.0-0.30.20.00.0-0.20.20.20.1-0.00.0-0.1-0.10.1-0.1
Reaction time false alarm rate0.20.30.7-0.4-0.50.20.30.30.3-0.70.60.40.5-0.80.60.80.6-0.5-0.1-0.4-0.40.7-0.7
Reaction time premature initiation rate0.10.10.60.8-0.20.4-0.5-0.50.4-0.00.10.30.20.20.0-0.1-0.1-0.00.10.10.1-0.1-0.1
Reaction time premature initiations0.10.22.3-1.50.20.1-0.4-0.50.00.5-0.4-0.0-0.10.5-0.4-0.4-0.20.10.40.10.1-0.10.1
Std. dev. reaction times0.00.10.30.50.1-0.30.50.5-0.20.1-0.0-0.1-0.30.1-0.00.0-0.20.30.30.20.2-0.40.3
Reaction time trials completed0.41.210.6-3.31.0-0.60.0-0.1-0.81.4-1.3-0.8-0.91.1-1.2-1.1-0.70.60.80.40.4-0.60.7
Reaction time trials AUC0.31.112.8-3.60.8-0.5-0.1-0.1-0.61.2-1.1-0.7-0.70.9-1.1-0.9-0.60.40.60.30.3-0.40.6
Run reversals in cocaine runway, females4.14.67.51.72.5-2.31.71.6-2.32.4-2.4-2.4-2.72.3-2.4-2.1-2.12.11.91.91.9-1.81.7
Run reversals in cocaine runway, males0.80.91.5-0.8-0.90.5-0.0-0.00.6-0.81.00.71.2-1.21.01.21.1-1.1-1.1-1.0-1.01.0-1.1
Latency to leave start box in cocaine runway0.30.52.00.8-0.2-0.51.31.4-0.4-0.70.6-0.10.1-1.10.61.00.6-0.4-0.2-0.4-0.40.4-0.4
Latency to leave start box in cocaine runway, F0.50.64.62.1-0.3-0.41.31.4-0.2-0.90.80.00.4-1.00.80.90.5-0.20.2-0.0-0.00.10.2
Latency to leave start box in cocaine runway, M0.20.22.1-1.40.0-0.10.00.0-0.10.0-0.1-0.1-0.4-0.1-0.00.20.3-0.3-0.4-0.5-0.50.5-0.6
Std. dev. time between licks in bursts0.00.10.80.90.1-0.0-0.1-0.1-0.00.2-0.1-0.0-0.40.2-0.1-0.1-0.0-0.1-0.4-0.1-0.10.1-0.1
Total sessions with >9 infusions1.31.62.5-0.6-1.51.1-0.6-0.61.2-1.51.61.31.2-1.51.61.51.4-1.5-1.2-1.2-1.21.0-1.2
Short access day 1 total inactive lever presses0.30.51.11.00.6-0.70.70.7-0.60.3-0.4-0.6-0.70.3-0.4-0.5-0.60.71.01.01.0-0.80.6
Short access day 10 total inactive lever presses0.96.313.23.62.6-2.62.42.3-2.62.4-2.3-2.6-2.42.1-2.3-2.2-2.42.62.62.72.7-2.51.9
Short access day 1 total infusions0.40.71.60.5-1.10.7-0.2-0.20.8-1.11.30.90.9-1.21.31.00.9-0.9-0.6-0.6-0.60.3-0.8
Short access day 10 total infusions0.10.10.80.9-0.20.10.20.20.1-0.40.40.2-0.1-0.40.40.30.2-0.10.0-0.0-0.0-0.0-0.4
Short access total infusions1.21.73.0-0.0-1.61.3-0.7-0.61.3-1.71.71.41.2-1.61.71.51.4-1.4-1.2-1.2-1.21.1-1.3
Short access day 1 locomotion0.40.62.91.70.5-0.81.01.0-0.70.4-0.3-0.6-0.60.3-0.3-0.4-0.60.60.91.11.1-1.10.4
Short access day 10 total locomotion0.83.16.32.51.5-2.12.52.5-1.91.1-1.1-1.8-1.20.7-1.1-1.0-1.51.62.01.91.9-2.02.2
Short access total locomotion0.20.41.71.30.2-0.61.01.0-0.50.00.1-0.4-0.2-0.20.10.0-0.30.30.70.70.7-0.70.7
One hour access (0.3 mA shock)0.20.30.7-0.90.5-0.70.70.7-0.70.5-0.5-0.6-0.70.2-0.5-0.4-0.40.40.50.40.4-0.50.3
Compulsive drug intake0.20.22.7-1.70.1-0.40.60.6-0.40.1-0.1-0.30.5-0.4-0.00.10.1-0.30.20.10.10.0-0.1
One hour access (shock baseline)0.10.20.50.10.4-0.50.50.5-0.50.4-0.3-0.5-0.60.3-0.3-0.4-0.50.50.50.60.6-0.70.6
Social response proportion0.50.61.41.0-0.70.6-0.3-0.20.6-0.70.80.70.7-0.80.80.90.8-0.8-1.2-0.8-0.80.8-1.0
Social responses0.50.71.7-0.7-0.70.5-0.2-0.20.5-0.70.70.60.5-0.90.70.91.0-0.9-1.3-1.0-1.01.2-1.1
Social time2.03.15.1-0.9-1.71.6-0.9-0.91.5-1.91.81.72.0-1.91.81.82.0-2.0-1.9-1.9-1.92.2-2.2
Soleus weight0.82.423.7-4.9-1.41.6-1.6-1.61.6-1.00.91.41.3-0.70.90.70.9-0.9-0.6-0.9-0.90.5-0.3
Bone: stiffness0.50.92.01.40.6-0.0-0.6-0.7-0.10.9-0.9-0.4-0.71.4-0.9-1.3-1.11.11.11.01.0-1.21.2
Tibialis anterior weight1.24.39.7-1.9-2.62.1-1.2-1.12.2-2.52.62.33.1-2.52.52.32.1-2.0-1.4-1.6-1.61.3-1.1
Time to tail flick, vehicle, before self-admin1.51.83.11.01.2-1.00.70.6-1.11.3-1.3-1.2-0.81.4-1.3-1.4-1.51.51.81.81.8-1.71.8
Time to tail flick, vehicle, after self-admin2.44.86.81.72.2-2.01.61.6-2.12.1-2.1-2.2-1.82.1-2.2-2.3-2.42.52.42.52.5-2.62.6
Time to tail flick, test, before self-admin0.50.60.90.9-0.90.9-0.7-0.70.9-0.80.90.90.5-0.60.90.80.7-0.8-0.6-0.7-0.70.6-0.6
Time to tail flick, test, after self-admin0.50.61.8-1.2-0.91.1-1.4-1.31.1-0.60.60.91.0-0.20.60.10.2-0.40.00.00.00.00.1
Delta time to tail flick, vehicle, before/after SA0.10.10.20.20.3-0.1-0.1-0.1-0.10.3-0.3-0.2-0.30.4-0.4-0.5-0.30.30.10.20.2-0.20.2
Delta time to tail flick, test, before/after SA0.20.32.6-1.6-0.00.4-0.7-0.80.20.1-0.20.10.20.4-0.2-0.5-0.30.20.40.40.4-0.20.3
Tibia length0.71.94.20.21.1-0.3-0.8-0.9-0.41.6-1.4-0.8-1.22.0-1.5-2.0-1.81.51.31.61.6-1.71.6
Ambulatory time before self-admin0.41.14.72.20.9-0.3-0.3-0.3-0.31.1-1.0-0.6-1.31.5-1.0-1.2-1.21.00.91.01.0-1.11.1
Ambulatory time after self-admin0.10.10.40.60.20.0-0.4-0.40.00.4-0.3-0.1-0.50.6-0.3-0.4-0.30.30.00.20.2-0.20.1
Bone: tissue strength3.03.26.90.11.8-0.9-0.3-0.4-1.12.2-2.2-1.5-2.02.6-2.2-2.4-2.11.91.91.81.8-1.71.4
Total heroin consumption0.80.91.90.3-1.21.2-0.9-0.91.2-1.41.31.20.7-0.91.21.00.9-0.7-0.7-0.6-0.60.6-0.7
Bone: trabecular number0.71.32.7-0.2-1.41.6-1.5-1.51.6-1.11.21.51.5-0.71.20.80.9-0.9-0.8-1.0-1.00.6-0.6
Bone: trabecular spacing0.71.02.50.61.2-1.51.61.6-1.40.9-0.9-1.3-1.40.5-0.9-0.5-0.70.70.60.60.6-0.50.7
Bone: trabecular thickness2.02.83.5-1.6-1.81.7-1.3-1.31.8-1.81.71.81.9-1.61.71.71.8-1.7-1.5-1.7-1.71.7-1.6
Bone: trabecular tissue density0.10.20.70.80.10.2-0.7-0.70.20.2-0.20.0-0.30.5-0.2-0.5-0.40.40.10.40.4-0.50.5
Water consumed over 24 hours0.00.00.10.1-0.30.3-0.3-0.30.3-0.10.20.30.2-0.10.20.10.1-0.1-0.00.00.0-0.10.0
Number of responses in last shaping day0.50.63.3-0.1-0.71.3-1.8-1.81.2-0.40.40.90.30.30.3-0.4-0.10.1-0.10.20.2-0.30.3