Lmo1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_063280885.1 0.02 0.02 5.7e-03 0 0.01 0.01 0.01 1.3e-01 2.9e-03 1.1e-02 2.1e-02
2 NAcc alternative TSS NM_139112.3 0.02 0.01 7.7e-03 0 0.01 0.01 0 2.2e-01 9.3e-03 1.8e-02 9.9e-02
3 NAcc gene expression Lmo1 0.11 0.09 3.0e-11 0.06 0.07 0.06 0.08 1.7e-09 1.0e-10 3.3e-09 6.1e-12
4 pVTA intron excision ratio chr1_172598243_172602946 0.05 0.04 8.2e-04 0.01 0.02 0.02 0.01 5.2e-02 1.3e-02 1.3e-02 2.3e-02
5 pVTA isoform ratio XM_006229968.3 0.08 0.05 9.8e-06 0.04 0.06 0.08 0.08 1.9e-04 9.6e-06 7.8e-07 8.0e-07
6 PL gene expression Lmo1 0.05 0.04 8.8e-05 0.04 0.03 0.04 0.03 7.7e-05 1.1e-04 3.6e-05 1.4e-04
7 NAcc isoform ratio NM_139112.3 0.02 0.02 3.1e-03 0.01 0.01 0.01 0.01 2.6e-03 7.6e-03 4.7e-03 6.8e-03
8 NAcc intron excision ratio chr1_172572208_172602946 0.03 0.03 3.0e-04 0.03 0.03 0.02 0.03 5.6e-05 5.9e-05 7.5e-04 1.0e-04
9 Brain gene expression Lmo1 0.04 0.03 2.8e-03 0.03 0.02 0.02 0.02 1.2e-03 4.4e-03 5.2e-03 3.4e-03
10 Adipose gene expression Lmo1 0.06 0.04 7.7e-06 0.04 0.05 0.05 0.05 7.4e-05 2.9e-06 6.5e-06 3.6e-06
11 Liver alternative TSS NM_001402442.1 0.05 0.04 2.3e-04 0.03 0.03 0.03 0.03 5.5e-04 2.6e-04 1.4e-04 3.3e-04
12 IC intron excision ratio chr1_172598243_172602946 0.07 0.06 9.3e-03 0.01 0.03 0.02 0.02 1.0e-01 2.7e-02 3.7e-02 5.4e-02
13 BLA intron excision ratio chr1_172598243_172602946 0.1 0.07 1.3e-04 0.07 0.08 0.09 0.08 8.3e-05 7.3e-05 2.5e-05 7.5e-05
14 Brain mRNA stability Lmo1 0.05 0.04 4.0e-04 0.05 0.03 0.04 0.04 2.7e-05 3.9e-04 6.4e-05 9.4e-05
15 NAcc intron excision ratio chr1_172572208_172597984 0.02 0.02 3.0e-03 0.02 0.01 0.01 0.02 4.4e-04 3.2e-03 5.2e-03 1.2e-03
16 NAcc isoform ratio XM_006229968.3 0.03 0.02 9.8e-04 0.02 0.02 0.01 0.02 4.4e-04 1.1e-03 2.2e-03 8.6e-04
17 pVTA intron excision ratio chr1_172572208_172597984 0.04 0.03 3.8e-03 0.02 0.03 0.02 0.02 1.2e-02 3.2e-03 5.6e-03 8.2e-03
18 pVTA intron excision ratio chr1_172572208_172602946 0.08 0.05 7.8e-06 0.07 0.06 0.05 0.06 3.6e-06 7.3e-06 4.4e-05 9.0e-06
19 BLA mRNA stability Lmo1 0.09 0.06 9.3e-04 0.05 0.04 0.02 0.03 1.3e-03 5.9e-03 1.9e-02 6.2e-03
20 BLA isoform ratio XM_006229968.3 0.11 0.08 2.5e-04 0.06 0.07 0.05 0.07 4.4e-04 1.9e-04 7.9e-04 1.8e-04
21 BLA intron excision ratio chr1_172572208_172602946 0.09 0.08 1.2e-03 0.06 0.05 0.04 0.05 7.3e-04 7.8e-04 2.4e-03 1.0e-03
22 Liver alternative TSS XM_063280885.1 0.03 0.02 6.9e-03 0 0.01 0.02 0.01 1.1e-01 1.7e-02 3.8e-03 2.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.10.21.4-0.50.5-0.5-1.2-0.60.4-0.5-0.50.5-0.2-0.1-0.3-0.30.10.30.3-0.2-0.00.00.0-0.00.1
Area under the delay curve0.30.40.9-0.70.9-0.7-0.00.20.9-0.8-0.80.80.1-0.1-1.00.5-0.40.50.5-0.9-0.7-0.7-0.7-0.6-0.8
BMI with tail2.17.428.25.3-5.34.62.02.4-3.83.53.5-3.52.6-1.92.71.1-0.20.10.12.00.30.30.30.41.1
BMI without tail1.78.930.45.4-5.55.12.02.0-4.44.14.1-4.22.2-1.33.20.60.4-0.6-0.62.51.00.80.80.92.1
Body weight1.35.817.84.0-4.23.90.50.8-3.63.43.4-3.41.1-0.43.0-0.20.9-1.1-1.12.51.21.31.31.42.1
Weight adjusted by age0.30.93.31.8-1.81.60.10.5-1.41.41.4-1.40.8-0.51.00.20.2-0.3-0.30.80.30.20.30.30.2
Bone surface0.10.10.8-0.50.6-0.5-0.9-0.50.4-0.4-0.40.4-0.2-0.0-0.4-0.20.10.20.1-0.3-0.1-0.1-0.1-0.10.1
Bone volume0.00.00.20.00.0-0.1-0.5-0.10.1-0.2-0.20.20.2-0.4-0.20.1-0.10.20.2-0.3-0.2-0.3-0.3-0.20.1
Breakpoint value in progressive ratio session0.61.13.00.7-0.40.21.61.40.2-0.3-0.30.41.3-1.5-0.81.4-1.71.11.1-0.9-1.0-1.0-1.0-1.1-0.9
Number of licking bursts0.10.40.7-0.50.7-0.70.60.60.8-0.7-0.70.70.2-0.3-0.80.7-0.50.50.5-0.8-0.5-0.6-0.6-0.6-0.7
Context. condit. distance diff. score1.01.24.10.8-0.50.32.01.60.2-0.2-0.20.21.5-1.3-0.81.5-1.41.00.9-0.9-1.4-1.2-1.2-1.3-1.1
Locomotion velocity, session 10.80.81.6-0.00.2-0.80.91.01.0-1.2-1.21.20.6-0.8-0.80.9-1.11.21.3-0.8-0.8-0.8-0.8-0.8-0.8
Locomotion distance, session 10.60.81.90.7-0.5-0.11.21.30.4-0.7-0.70.71.1-1.2-0.51.1-1.11.21.4-0.6-1.0-0.8-0.8-0.8-0.8
Locomotion velocity, session 20.60.71.70.6-0.40.01.21.10.3-0.5-0.50.51.0-1.1-0.51.0-1.01.21.3-0.6-0.8-0.8-0.8-0.9-0.7
Locomotion distance, session 21.72.46.42.2-1.81.42.52.4-0.60.40.4-0.42.3-2.0-0.31.9-1.61.71.8-0.6-1.3-1.4-1.4-1.4-0.7
Locomotion velocity, session 30.10.20.60.8-0.80.50.70.6-0.40.30.3-0.40.3-0.10.50.3-0.10.10.20.40.20.10.10.10.3
Locomotion distance, session 30.20.21.30.7-0.70.81.10.5-0.60.60.6-0.70.20.10.40.2-0.0-0.20.00.30.10.20.10.2-0.0
Stereotopy head waving bouts, day 30.20.20.7-0.70.7-0.80.0-0.20.6-0.8-0.80.8-0.30.1-0.3-0.1-0.10.20.1-0.2-0.1-0.0-0.0-0.10.1
Stereotopy head waving duration, day 30.10.20.40.3-0.2-0.20.70.60.2-0.4-0.40.40.5-0.6-0.20.5-0.50.60.4-0.2-0.5-0.3-0.3-0.4-0.0
Locomotion velocity, session 73.53.86.90.20.3-0.62.22.21.3-1.2-1.21.22.1-2.2-2.22.4-2.32.12.1-2.3-2.6-2.5-2.5-2.4-2.1
Locomotion distance, session 71.01.22.5-0.30.6-0.71.61.21.0-0.9-0.90.90.8-0.9-1.31.3-1.31.01.0-1.3-1.4-1.3-1.3-1.3-1.3
Stereotopy head waving bouts, day 70.00.00.20.0-0.00.00.40.1-0.1-0.2-0.20.20.0-0.2-0.00.0-0.10.30.3-0.0-0.10.00.0-0.0-0.1
Stereotopy head waving duration, day 70.30.41.31.0-1.11.10.30.1-1.10.80.8-0.80.2-0.20.8-0.20.3-0.1-0.10.70.40.50.50.40.5
Locomotion velocity, session 82.53.14.4-0.20.7-1.01.51.61.6-1.7-1.71.71.5-1.8-2.01.9-2.02.12.1-2.0-2.1-2.0-2.0-2.1-1.8
Locomotion distance, session 81.82.68.81.8-1.41.23.02.5-0.30.30.3-0.32.3-2.0-0.72.2-1.81.51.6-1.0-1.7-1.7-1.7-1.8-1.0
Degree of sensitization distance1.01.01.90.4-0.1-0.21.01.20.5-0.5-0.50.51.2-1.4-1.01.3-1.21.21.0-1.1-1.3-1.3-1.3-1.3-0.9
Degree of sensitization stereotypy0.10.10.50.5-0.50.50.70.3-0.40.20.2-0.20.4-0.50.10.2-0.20.40.40.0-0.2-0.1-0.1-0.1-0.2
Conditioned locomotion0.60.71.7-1.00.8-0.7-0.5-0.90.2-0.2-0.20.3-1.31.30.4-1.00.8-0.9-1.00.60.91.01.01.00.3
Cocaine response after cond. corrected0.71.11.9-0.20.5-1.00.90.91.0-1.4-1.41.40.7-0.8-1.11.0-1.21.01.1-1.1-1.2-1.0-1.0-1.0-1.3
Cocaine response after cond. not corrected0.30.52.10.7-0.50.11.51.2-0.0-0.4-0.40.30.9-0.7-0.31.0-0.90.60.7-0.4-0.7-0.7-0.7-0.7-0.5
Cocaine response before conditioning0.70.82.41.4-1.51.61.10.7-1.41.41.4-1.40.6-0.20.80.30.2-0.3-0.30.60.30.10.10.10.9
Saline control response1.82.54.91.0-1.31.8-0.3-0.8-1.92.22.2-2.2-0.61.21.8-1.21.5-1.9-1.91.71.51.41.41.41.5
Bone: connectivity density0.10.11.1-0.30.3-0.3-1.0-0.30.3-0.3-0.30.30.0-0.3-0.3-0.1-0.00.40.4-0.3-0.2-0.2-0.2-0.2-0.0
Bone: cortical apparent density0.30.41.4-1.21.1-1.2-0.4-0.50.9-0.9-0.90.9-0.80.7-0.4-0.30.1-0.3-0.2-0.20.10.20.20.2-0.4
Bone: cortical area0.10.20.50.5-0.40.30.20.5-0.00.00.0-0.00.7-0.7-0.30.5-0.50.50.5-0.4-0.6-0.5-0.5-0.5-0.3
Bone: cortical porosity0.10.20.8-0.30.3-0.1-0.9-0.7-0.00.10.1-0.1-0.40.30.1-0.50.4-0.5-0.60.10.30.30.30.20.3
Bone: cortical porosity0.40.42.0-0.90.8-0.5-1.4-1.10.2-0.1-0.10.1-0.80.70.0-0.80.7-0.7-0.80.20.50.50.50.40.3
Bone: cortical thickness0.20.30.80.8-0.70.50.30.7-0.20.20.2-0.20.9-0.9-0.10.7-0.50.50.5-0.3-0.6-0.5-0.5-0.5-0.3
Bone: cortical thickness0.80.92.20.8-0.50.20.61.10.3-0.4-0.40.41.4-1.5-0.71.2-1.11.21.2-0.9-1.2-1.2-1.2-1.2-0.7
Bone: cortical tissue density0.30.41.3-1.11.1-1.1-0.4-0.50.8-0.8-0.80.8-0.80.8-0.3-0.40.1-0.3-0.2-0.10.20.30.30.3-0.3
Condit. Reinf. active minus inactive responses1.72.03.3-0.1-0.20.6-1.2-1.5-1.21.21.2-1.2-1.41.51.4-1.71.7-1.7-1.81.51.61.71.71.61.2
Condit. Reinf. active-inactive response ratio1.92.13.7-0.40.00.3-1.8-1.9-1.00.90.9-0.9-1.61.61.4-1.91.8-1.6-1.61.51.71.81.81.71.3
Condit. Reinf. active responses2.02.64.4-0.3-0.20.6-1.5-1.8-1.21.21.2-1.2-1.71.91.6-2.01.9-2.0-2.11.71.91.91.91.91.5
Condit. Reinf. inactive responses0.40.51.00.3-0.50.6-0.2-0.4-0.80.70.7-0.8-0.50.70.9-0.60.8-1.0-1.00.90.80.80.80.80.8
Incentive salience index mean1.51.93.3-0.70.30.0-1.6-1.8-0.70.60.6-0.7-1.71.81.2-1.81.7-1.7-1.81.41.61.71.71.71.1
Condit. Reinf. lever presses0.81.12.5-1.10.8-0.7-1.6-1.60.1-0.2-0.20.2-1.51.40.6-1.51.1-1.1-1.20.81.11.31.31.30.6
Condit. Reinf. active minus inactive responses0.20.30.70.5-0.60.7-0.2-0.2-0.80.70.7-0.8-0.10.30.7-0.40.5-0.6-0.50.60.50.50.50.50.4
Condit. Reinf. active-inactive response ratio0.10.20.4-0.0-0.10.3-0.1-0.3-0.50.50.5-0.5-0.30.50.4-0.40.5-0.6-0.50.40.40.40.40.40.3
Condit. Reinf. active responses0.20.31.10.9-0.91.0-0.00.1-0.90.90.9-0.90.3-0.10.6-0.10.3-0.3-0.20.50.30.20.20.20.3
Condit. Reinf. inactive responses0.40.62.31.5-1.41.40.40.7-0.91.01.0-0.90.9-0.70.50.4-0.20.20.20.3-0.1-0.1-0.1-0.10.1
Condit. Reinf. lever presses1.01.44.82.2-2.22.10.90.9-1.61.71.7-1.71.0-0.61.10.40.0-0.1-0.10.90.10.20.20.20.2
Condit. Reinf. lever reinforcers received0.20.30.70.6-0.70.8-0.10.0-0.80.80.8-0.80.10.10.5-0.10.3-0.4-0.30.50.30.30.30.30.2
Conditioned reinforcement - actives0.10.51.31.1-1.11.10.90.7-0.91.01.0-1.00.6-0.00.50.20.7-0.3-0.30.30.0-0.0-0.00.00.1
Conditioned reinforcement - inactives0.10.20.5-0.30.4-0.5-0.40.00.7-0.7-0.70.70.3-0.0-0.60.10.30.70.7-0.6-0.6-0.4-0.4-0.5-0.5
Conditioned locomotion1.01.53.40.1-0.40.7-0.9-1.1-1.21.11.1-1.1-1.11.41.4-1.31.9-1.4-1.41.41.41.41.41.31.5
Patch foraging indifference point 0 sec0.61.84.71.7-1.82.20.5-0.2-2.02.02.0-2.10.20.21.5-0.50.9-1.1-1.01.30.91.00.90.91.2
Patch foraging indifference point AUC0.10.20.4-0.00.1-0.30.30.40.4-0.6-0.60.60.3-0.5-0.40.4-0.50.60.6-0.4-0.4-0.3-0.3-0.4-0.6
Delay disc. indifference point, 0s delay0.10.10.40.6-0.50.4-0.40.3-0.10.10.1-0.10.5-0.4-0.00.3-0.10.30.3-0.1-0.2-0.1-0.1-0.2-0.4
Delay disc. indifference point, 16s delay0.81.12.3-0.60.9-1.00.10.31.3-1.2-1.21.20.7-0.7-1.50.9-0.81.11.1-1.5-1.3-1.3-1.3-1.2-1.0
Delay disc. indifference point, 2s delay0.20.31.0-1.00.9-0.5-0.3-0.40.3-0.4-0.40.2-0.90.8-0.1-0.30.6-0.4-0.40.00.30.40.40.4-0.1
Delay disc. indifference point, 24s delay0.10.10.5-0.10.10.40.2-0.2-0.40.70.7-0.6-0.10.4-0.0-0.10.4-0.7-0.70.00.0-0.2-0.10.1-0.2
Delay disc. indifference point, 4s delay0.70.72.4-1.41.4-1.2-0.1-0.11.2-1.5-1.51.3-0.80.5-0.70.1-0.00.40.5-0.5-0.1-0.1-0.1-0.0-0.2
Delay disc. indifference point, 8s delay0.20.41.2-0.00.2-0.20.10.70.7-0.4-0.40.40.6-0.5-0.80.8-0.50.50.5-0.8-0.8-0.8-0.8-0.7-1.1
Indifference point function ln k0.10.41.10.9-1.01.10.70.3-1.01.11.1-1.10.20.10.7-0.00.2-0.4-0.50.60.30.30.30.40.4
Indifference point function log k0.10.41.10.9-1.01.10.70.3-1.01.11.1-1.10.20.10.7-0.00.2-0.4-0.50.60.30.30.30.40.4
Patch foraging total patch changes 0 sec0.82.45.71.8-2.02.40.7-0.2-2.32.32.3-2.30.10.51.8-0.71.1-1.3-1.31.61.21.21.11.11.5
Patch foraging total patch changes 12 sec0.10.20.40.6-0.60.7-0.4-0.3-0.50.60.6-0.60.2-0.20.4-0.30.3-0.2-0.20.30.20.50.30.20.2
Patch foraging total patch changes 18 sec0.41.02.01.1-1.31.3-0.0-0.4-1.41.31.3-1.3-0.10.41.3-0.70.9-0.9-0.91.20.91.01.00.91.1
Patch foraging total patch changes 24 sec0.10.31.20.3-0.40.5-0.1-0.4-0.70.40.4-0.5-0.30.30.6-0.50.6-0.5-0.50.60.70.50.50.51.1
Patch foraging total patch changes 6 sec0.30.51.61.3-1.21.20.90.6-0.80.70.7-0.71.0-0.80.20.5-0.30.30.40.0-0.3-0.2-0.2-0.40.1
Patch foraging time to switch 0 sec0.20.82.4-1.51.5-1.5-0.9-0.61.4-1.3-1.31.4-0.60.2-0.9-0.1-0.20.30.3-0.7-0.2-0.3-0.3-0.3-0.3
Patch foraging water rate 0 sec0.10.20.50.6-0.60.70.60.2-0.70.70.7-0.70.10.10.5-0.10.3-0.5-0.50.50.20.40.30.30.3
Patch foraging water rate 12 sec0.52.07.32.7-2.62.31.91.8-1.61.61.6-1.61.8-1.30.91.1-0.60.30.30.5-0.4-0.3-0.3-0.30.1
Patch foraging water rate 18 sec0.30.82.91.4-1.21.11.71.3-0.70.80.8-0.81.2-0.80.11.0-0.70.40.4-0.1-0.6-0.7-0.6-0.5-0.1
Patch foraging water rate 24 sec0.60.82.61.3-1.11.01.61.5-0.60.60.6-0.61.3-1.0-0.11.1-0.80.70.7-0.3-0.8-0.6-0.7-0.6-0.3
Patch foraging water rate 6 sec0.10.10.6-0.0-0.10.30.70.1-0.30.40.4-0.4-0.20.40.2-0.10.2-0.3-0.30.20.10.30.20.20.4
Seeking ratio, delayed vs. immediate footshock0.50.72.9-1.71.7-1.50.4-0.41.0-1.1-1.11.1-0.80.4-0.8-0.1-0.60.10.1-0.5-0.3-0.3-0.3-0.20.1
Distance traveled before self-admin0.10.21.3-0.80.7-0.5-1.2-0.80.3-0.2-0.20.2-0.70.5-0.1-0.60.4-0.3-0.30.00.20.20.20.20.0
Distance traveled after self-admin0.40.71.20.4-0.60.7-1.0-0.4-1.00.90.9-0.9-0.60.61.1-0.51.1-0.9-0.91.11.00.80.81.00.3
Extensor digitorum longus weight0.31.02.91.3-1.10.60.61.3-0.00.10.1-0.01.5-1.7-0.41.2-1.11.41.4-0.6-1.1-1.0-1.0-1.0-0.7
Bone: elastic displacement0.10.10.20.2-0.10.3-0.30.1-0.10.30.3-0.30.4-0.3-0.30.2-0.1-0.0-0.1-0.3-0.3-0.4-0.4-0.4-0.1
Bone: elastic work0.10.20.40.5-0.30.40.20.4-0.20.30.3-0.30.6-0.5-0.30.5-0.30.20.2-0.3-0.4-0.5-0.5-0.5-0.1
Bone: endosteal estimation0.10.30.7-0.50.6-0.70.40.20.6-0.8-0.80.80.2-0.3-0.70.4-0.50.50.5-0.7-0.5-0.5-0.5-0.6-0.4
Bone: endosteal perimeter0.30.71.4-0.60.8-0.80.20.30.9-0.9-0.90.90.5-0.7-1.20.7-0.80.80.7-1.1-1.0-1.0-1.0-1.0-0.8
Epididymis fat weight0.10.41.51.2-1.21.00.50.4-0.90.80.8-0.70.5-0.40.70.10.00.0-0.00.50.20.20.20.10.6
Delta time in closed arm before/after self-admin1.91.73.40.20.2-0.31.41.51.0-0.6-0.60.71.6-1.3-1.51.5-1.61.41.4-1.7-1.7-1.8-1.8-1.8-0.9
Delta time in open arm before/after self-admin2.53.05.21.1-1.51.6-0.9-1.1-2.11.91.9-2.0-0.91.12.3-1.61.8-1.7-1.72.21.92.02.01.91.6
Diff in mean of infusions in LGA sessions0.10.21.0-0.10.2-0.40.20.60.4-0.6-0.60.60.3-0.3-0.50.6-0.20.60.6-0.5-0.4-0.3-0.3-0.4-1.0
Delay discount exponential model param0.30.40.90.8-0.90.6-0.0-0.2-0.90.80.8-0.7-0.0-0.00.9-0.50.3-0.4-0.40.90.60.60.60.50.7
Extinction: sum of active levers before priming0.10.10.3-0.20.3-0.20.00.10.3-0.4-0.40.40.1-0.3-0.40.2-0.50.40.4-0.4-0.3-0.3-0.3-0.2-0.0
Active lever presses in extinction session 61.21.23.10.6-0.30.11.11.70.3-0.5-0.50.51.3-1.6-0.91.8-1.41.31.3-1.1-1.2-1.2-1.2-1.2-1.3
Bone: final force0.30.51.4-0.30.1-0.0-1.2-1.0-0.30.30.3-0.3-0.90.80.7-1.00.9-0.7-0.70.80.91.01.00.90.7
Bone: final moment0.40.61.4-0.1-0.10.2-1.2-0.9-0.50.40.4-0.4-0.80.70.8-1.00.9-0.8-0.80.90.91.01.01.00.8
Food consumed during 24 hour testing period0.20.43.50.6-0.60.8-0.6-0.9-0.70.70.7-0.80.4-0.20.2-0.8-0.0-0.10.00.10.1-0.2-0.2-0.21.9
Glucose0.10.20.5-0.40.5-0.5-0.1-0.10.4-0.7-0.70.7-0.0-0.1-0.40.1-0.20.40.3-0.4-0.2-0.2-0.2-0.2-0.5
Heart weight0.30.51.91.3-1.41.10.60.6-1.10.90.9-0.90.6-0.40.80.20.1-0.1-0.10.60.20.10.20.20.6
Delay discount hyperbolic model param0.20.30.90.9-1.00.60.1-0.1-0.80.80.8-0.70.2-0.20.8-0.30.1-0.2-0.20.70.40.40.40.30.6
Intermittent access intake day 1-15 change0.10.40.9-0.70.8-0.9-0.40.01.0-0.9-0.90.90.10.0-0.80.10.10.70.7-0.7-0.6-0.6-0.5-0.6-0.1
Intermittent access intake escalation0.10.41.0-0.80.9-1.0-0.6-0.21.0-0.9-0.90.9-0.00.1-0.8-0.10.20.60.6-0.7-0.5-0.5-0.5-0.50.1
Intermittent access intake escalation 20.10.20.4-0.30.4-0.6-0.20.00.6-0.5-0.50.50.2-0.1-0.5-0.0-0.20.50.5-0.5-0.5-0.4-0.4-0.50.3
Intermitt. access day 1 inactive lever presses0.00.41.1-1.01.1-1.0-0.1-0.20.9-0.9-0.90.8-0.30.4-0.7-0.20.20.40.4-0.6-0.3-0.2-0.2-0.4-0.1
Intermitt. access day 15 inactive lever presses0.10.40.80.00.1-0.4-0.5-0.10.7-0.7-0.70.70.6-0.2-0.70.0-0.00.90.9-0.8-0.8-0.8-0.7-0.8-0.2
Intermitt. access escalation Index0.20.61.40.2-0.50.60.1-0.7-0.80.70.7-0.7-0.60.61.0-0.90.5-0.9-0.91.00.90.90.90.91.2
Intermittent access day 1 total infusions0.00.10.5-0.0-0.10.2-0.10.0-0.40.40.4-0.5-0.40.40.4-0.00.2-0.7-0.70.40.50.50.50.40.1
Intermittent access day 15 total infusions0.10.20.7-0.80.8-0.8-0.6-0.10.6-0.6-0.60.6-0.40.5-0.4-0.10.5-0.1-0.1-0.3-0.1-0.1-0.1-0.20.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.20.2-0.2-0.20.10.10.00.0-0.0-0.10.3-0.1-0.10.3-0.3-0.3-0.00.00.10.1-0.10.3
Intermittent access total infusions0.20.20.6-0.30.20.0-0.2-0.3-0.20.30.3-0.3-0.50.70.3-0.30.6-0.7-0.70.30.50.50.50.40.3
Intermittent access day 1 locomotion0.50.81.9-1.10.8-0.5-1.2-1.10.0-0.0-0.0-0.0-1.41.20.4-1.01.3-1.1-1.10.61.01.11.10.90.7
Intermittent access day 15 total locomotion0.31.02.4-0.40.10.0-1.4-1.2-0.40.50.5-0.5-1.11.20.9-1.21.6-1.1-1.11.01.11.11.11.11.2
Intermittent access total locomotion0.70.82.1-0.60.4-0.1-1.2-1.1-0.30.40.4-0.4-1.11.20.7-1.11.5-1.1-1.10.81.01.11.10.90.9
Intermittent access standard deviation0.10.61.30.4-0.10.00.90.80.3-0.2-0.20.21.1-0.7-0.80.9-0.50.80.8-0.9-1.1-1.1-1.1-1.1-0.7
Left kidney weight0.21.55.22.1-2.31.90.40.5-1.81.51.5-1.50.6-0.31.6-0.10.3-0.2-0.21.40.70.80.80.81.4
Right kidney weight0.32.17.72.8-2.82.60.91.0-2.12.02.0-1.91.2-0.81.50.30.10.00.11.10.30.40.40.40.9
Cocaine induced anxiety0.10.21.0-0.50.4-0.3-1.0-1.0-0.00.00.0-0.0-0.60.60.1-0.70.4-0.6-0.60.20.40.30.30.30.4
Post-drug Anxiety1.01.13.1-1.51.6-1.8-0.9-0.41.6-1.6-1.61.6-0.4-0.1-1.20.1-0.80.50.5-1.0-0.6-0.5-0.5-0.5-1.1
Baseline Anxiety0.61.02.0-1.01.1-1.30.40.71.4-1.4-1.41.40.0-0.6-1.10.7-1.01.11.1-1.0-0.9-0.7-0.7-0.7-1.3
Tail length0.52.86.4-0.4-0.00.6-1.3-1.9-1.31.31.3-1.3-1.82.01.6-2.02.1-2.1-2.01.72.11.81.81.92.5
Length with tail0.20.81.6-0.60.4-0.2-1.1-1.2-0.40.40.4-0.4-1.21.30.6-1.11.1-1.2-1.20.81.11.01.01.01.3
Length without tail0.10.71.7-1.31.1-1.0-1.3-1.10.6-0.5-0.50.5-1.21.1-0.0-0.90.6-0.7-0.70.20.50.60.60.70.3
Times rat made contact with spout0.20.21.2-0.30.3-0.3-1.1-1.00.3-0.4-0.40.3-0.20.1-0.1-0.80.00.00.1-0.10.10.10.10.00.8
Lifetime Intake0.10.10.50.1-0.20.40.1-0.1-0.40.50.5-0.5-0.20.40.3-0.10.6-0.7-0.70.30.30.30.30.20.0
Liver weight, left0.50.82.30.1-0.30.2-1.3-1.0-0.50.40.4-0.3-0.80.81.0-1.11.0-0.8-0.81.01.11.11.11.11.5
Liver weight, right0.20.42.6-0.30.1-0.3-1.6-0.9-0.0-0.1-0.10.1-0.60.40.4-0.80.6-0.4-0.40.50.60.60.60.61.1
Locomotor activity0.91.44.72.2-1.91.20.51.6-0.70.40.4-0.41.9-1.90.21.3-1.01.21.2-0.2-0.7-1.0-0.9-0.8-0.6
Locomotor testing distance0.71.87.42.7-2.51.90.81.7-1.31.11.1-1.12.0-1.80.61.2-0.80.90.80.2-0.5-0.7-0.7-0.6-0.5
Locomotor testing rearing0.20.62.51.6-1.51.00.41.0-0.80.70.7-0.71.1-0.90.50.7-0.40.40.40.2-0.2-0.3-0.3-0.2-0.4
Locomotion in novel chamber0.10.10.40.3-0.40.20.50.1-0.2-0.2-0.20.2-0.1-0.30.4-0.0-0.50.20.20.40.30.60.50.40.1
Locomotion in novel chamber post-restriction0.10.31.1-1.01.0-1.00.3-0.10.9-0.9-0.90.9-0.60.3-0.40.0-0.30.10.1-0.3-0.10.10.00.0-0.1
Fecal boli incidents, locomotor time 10.71.86.5-2.62.4-1.9-2.4-1.61.2-1.0-1.01.0-1.91.4-0.5-1.11.2-0.7-0.7-0.10.50.70.70.5-0.2
Change in fecal boli incidents, locomotor task3.63.86.60.30.3-0.71.71.91.4-1.6-1.61.62.0-2.1-2.12.2-2.32.52.5-2.2-2.3-2.6-2.5-2.3-1.9
Time >=10cm from walls, locomotor time 10.10.10.4-0.0-0.10.2-0.6-0.4-0.30.50.5-0.4-0.30.30.4-0.40.6-0.5-0.50.40.40.20.30.40.0
Bouts of movement, locomotor time 10.00.00.1-0.10.2-0.10.30.20.1-0.1-0.10.20.0-0.1-0.20.1-0.10.00.0-0.2-0.1-0.3-0.2-0.1-0.2
Total resting periods, locomotor time 10.30.40.7-0.50.6-0.60.40.40.7-0.7-0.70.80.2-0.4-0.80.5-0.50.50.5-0.8-0.5-0.7-0.7-0.5-0.7
Rest time, locomotor task time 13.15.09.2-2.32.7-2.8-0.50.43.0-2.9-2.93.00.3-1.0-2.91.5-1.42.22.1-2.7-2.2-2.0-1.9-2.1-2.6
Distance moved, locomotor task time 11.33.86.71.6-2.12.1-0.0-0.7-2.42.32.3-2.4-0.71.12.6-1.61.3-2.0-1.92.42.12.22.12.02.4
Vertical activity count, locomotor time 10.53.26.01.8-2.22.3-0.4-0.5-2.32.42.4-2.4-0.30.82.3-1.31.2-1.7-1.72.11.81.71.61.72.0
Time >=10cm from walls, locomotor time 20.30.93.01.3-1.10.81.41.7-0.30.40.4-0.31.3-1.2-0.11.2-1.00.60.6-0.3-0.6-0.7-0.6-0.7-1.3
Bouts of movement, locomotor time 20.00.10.3-0.20.10.1-0.4-0.4-0.1-0.0-0.0-0.2-0.30.40.2-0.50.2-0.3-0.30.20.30.30.30.30.5
Total resting periods, locomotor time 20.00.10.2-0.40.4-0.2-0.4-0.40.3-0.4-0.40.2-0.20.2-0.2-0.3-0.00.10.1-0.2-0.0-0.00.0-0.00.4
Rest time, locomotor task time 21.01.83.3-0.91.2-1.20.40.91.5-1.5-1.51.30.6-0.8-1.71.3-1.11.51.5-1.6-1.4-1.5-1.4-1.4-1.8
Distance moved, locomotor task time 21.01.33.61.7-1.91.60.60.5-1.61.51.5-1.40.3-0.21.5-0.20.2-0.7-0.71.30.81.21.00.80.6
Vertical activity count, locomotor time 20.10.10.40.6-0.60.4-0.40.2-0.40.60.6-0.40.2-0.10.4-0.2-0.1-0.3-0.30.30.20.30.20.10.1
Light reinforcement 10.00.10.80.0-0.10.2-0.9-0.6-0.10.10.1-0.2-0.2-0.00.2-0.50.4-0.1-0.00.30.20.30.40.2-0.0
Light reinforcement 20.20.31.21.1-1.01.1-0.20.3-0.60.70.7-0.70.9-0.90.10.3-0.20.50.5-0.0-0.2-0.3-0.3-0.40.3
Bone: marrow area0.10.30.7-0.60.7-0.80.30.10.6-0.9-0.90.90.1-0.3-0.70.3-0.50.50.5-0.7-0.5-0.5-0.5-0.5-0.4
Bone: maximum diameter0.20.30.80.8-0.60.50.70.7-0.20.20.2-0.20.9-0.9-0.20.7-0.60.70.7-0.4-0.7-0.6-0.6-0.6-0.3
Bone: maximum force0.10.20.7-0.50.4-0.2-0.8-0.8-0.10.00.0-0.0-0.70.50.2-0.70.6-0.4-0.40.30.50.50.50.50.4
Bone: maximum moment0.10.20.5-0.20.10.1-0.7-0.7-0.40.30.3-0.3-0.50.40.4-0.60.6-0.5-0.50.40.50.50.50.50.4
Mean time between licks in bursts0.00.20.6-0.40.3-0.1-0.8-0.20.00.20.2-0.2-0.60.40.2-0.20.6-0.5-0.60.30.40.40.40.5-0.5
Mean num. licks in bursts0.20.51.50.2-0.40.4-1.2-1.2-0.50.40.4-0.4-0.40.40.7-1.20.5-0.4-0.40.70.60.60.60.61.2
Cd content in liver1.11.24.2-2.01.9-1.5-1.4-1.11.2-0.9-0.90.9-1.61.3-0.4-0.70.8-0.8-0.8-0.10.70.70.70.7-0.6
Co content in liver0.40.51.0-0.20.4-0.4-0.1-0.40.8-0.7-0.70.70.6-0.7-0.9-0.0-0.90.70.7-0.9-1.0-0.8-0.8-0.80.4
Cu content in liver3.03.55.50.8-1.31.6-1.5-1.2-2.02.12.1-2.1-1.31.42.3-1.62.2-2.1-2.12.32.12.22.22.21.6
Fe content in liver0.00.00.1-0.10.10.10.20.1-0.00.20.2-0.2-0.30.40.2-0.00.2-0.3-0.30.20.20.30.30.20.1
K content in liver1.11.11.60.3-0.60.8-1.1-0.7-1.11.31.3-1.3-0.70.81.2-0.91.2-1.2-1.21.21.11.31.31.20.6
Mg content in liver2.62.87.32.0-2.32.5-0.8-0.2-2.32.72.7-2.70.20.22.0-0.71.2-1.2-1.21.71.11.11.11.11.3
Mn content in liver1.61.72.90.3-0.71.0-0.4-0.8-1.51.31.3-1.3-1.01.41.6-1.11.6-1.7-1.71.61.51.51.51.51.2
Na content in liver0.10.20.40.6-0.50.50.50.6-0.10.30.3-0.30.6-0.5-0.10.5-0.40.30.3-0.2-0.4-0.4-0.4-0.4-0.2
Rb content in liver3.84.58.0-0.80.10.4-1.5-1.5-1.41.41.4-1.4-2.62.82.2-1.92.8-2.8-2.82.52.82.82.82.81.1
Se content in liver0.81.02.1-0.50.20.2-0.3-0.8-0.70.70.7-0.7-1.21.50.9-1.01.2-1.4-1.41.01.21.21.21.20.5
Sr content in liver1.51.35.51.2-0.90.72.41.5-0.0-0.1-0.10.11.6-1.3-0.61.3-1.41.21.2-0.8-1.2-1.2-1.2-1.2-0.6
Zn content in liver1.51.75.72.4-2.42.30.40.6-1.82.02.0-2.01.1-0.91.20.20.1-0.2-0.20.90.10.20.20.20.8
Bone: minimum diameter0.50.91.6-0.40.7-0.80.70.70.9-1.0-1.01.00.7-0.8-1.21.0-1.01.01.1-1.2-1.1-1.1-1.1-1.1-1.0
Time in familiar zone, hab. session 11.61.73.70.20.2-0.21.91.70.8-0.5-0.50.51.4-1.1-1.51.7-1.51.21.2-1.6-1.7-1.7-1.7-1.7-1.4
Time in novel zone, hab. session 10.20.21.3-0.40.3-0.6-1.1-0.60.3-0.6-0.60.6-0.3-0.10.0-0.40.20.10.10.10.20.20.20.20.2
Total zone transitions, hab. session 10.40.51.50.9-1.01.20.80.1-1.21.01.0-1.00.20.10.7-0.20.3-0.4-0.30.60.50.40.40.30.6
Total locomotion distance, hab. session 10.30.51.30.3-0.41.00.5-0.2-1.01.11.1-1.1-0.20.60.5-0.30.6-0.7-0.60.50.70.40.40.40.7
Locomotion velocity, hab. session 10.81.12.60.6-0.81.40.3-0.5-1.51.61.6-1.6-0.40.91.1-0.71.1-1.1-1.01.01.10.80.80.81.2
Time in familiar zone, hab. session 20.70.83.01.4-1.41.61.71.1-1.11.31.3-1.30.8-0.20.50.6-0.20.00.00.3-0.1-0.1-0.1-0.10.1
Time in novel zone, hab. session 20.00.10.50.1-0.0-0.2-0.7-0.20.2-0.3-0.30.30.1-0.5-0.1-0.0-0.10.10.1-0.1-0.1-0.1-0.1-0.10.1
Total zone transitions, hab. session 20.70.93.21.7-1.81.50.90.7-1.41.11.1-1.10.7-0.41.10.20.1-0.10.00.80.20.30.30.30.6
Total locomotion distance, hab. session 20.60.82.81.7-1.71.70.60.6-1.41.31.3-1.30.8-0.60.80.30.1-0.00.00.60.10.10.10.00.6
Locomotion velocity, hab. session 20.60.92.71.6-1.61.60.40.4-1.51.31.3-1.30.6-0.31.00.00.3-0.3-0.20.80.30.30.30.30.8
Novel to familiar place preference ratio2.22.85.4-0.60.20.2-2.3-2.2-1.01.01.0-1.0-1.91.81.5-2.12.1-2.0-1.91.72.01.91.91.92.0
Novelty place preference1.31.73.8-0.60.20.0-1.9-1.8-0.80.70.7-0.7-1.51.41.1-1.71.6-1.5-1.41.31.61.41.41.41.6
Time in novel zone, NPP test1.01.33.2-0.50.10.1-1.8-1.6-0.70.70.7-0.7-1.21.11.0-1.51.4-1.3-1.21.11.41.21.21.21.4
Total zone transitions, NPP test0.30.41.20.9-0.80.51.10.9-0.30.10.1-0.10.9-0.8-0.10.7-0.60.50.6-0.3-0.6-0.5-0.5-0.6-0.3
Total locomotion distance, NPP test1.11.53.71.8-1.51.41.91.8-0.70.70.7-0.71.9-1.5-0.31.5-1.11.01.1-0.5-1.0-1.2-1.2-1.2-0.3
Locomotion velocity, NPP test1.01.43.41.8-1.51.41.81.7-0.80.80.8-0.81.8-1.4-0.21.4-1.00.80.9-0.4-0.9-1.1-1.1-1.1-0.2
Intraocular pressure0.10.20.7-0.60.5-0.4-0.9-0.70.3-0.1-0.10.1-0.50.30.0-0.50.4-0.3-0.30.10.30.20.20.30.6
Delta distance traveled before/after self-admin0.70.81.71.2-1.31.20.10.3-1.31.21.2-1.20.10.21.2-0.20.8-0.6-0.61.10.80.70.70.80.7
Delta ambulatory time before/after self-admin0.30.51.00.5-0.70.6-0.0-0.0-1.00.80.8-0.8-0.40.41.0-0.30.7-0.7-0.71.00.90.90.90.90.8
Parametrial fat weight0.71.62.71.3-1.51.6-1.3-0.7-1.61.61.6-1.6-0.30.51.6-1.01.1-1.1-1.11.51.11.11.21.21.6
Pavlov. Cond. lever latency0.60.74.60.9-0.70.52.11.4-0.20.10.1-0.11.0-0.7-0.21.1-0.90.70.7-0.4-0.7-0.8-0.8-0.7-0.6
Pavlov. Cond. magazine entry latency0.10.10.30.3-0.20.1-0.10.2-0.1-0.0-0.0-0.00.4-0.6-0.20.3-0.30.30.3-0.3-0.4-0.3-0.3-0.4-0.4
Pavlov. Cond. change in total contacts0.91.03.3-1.81.8-1.5-1.8-1.41.1-1.1-1.11.1-1.10.6-0.7-0.80.4-0.2-0.2-0.40.10.20.20.2-0.3
Pavlov. Cond. index score0.10.11.4-0.40.4-0.3-1.2-0.60.2-0.2-0.20.1-0.2-0.1-0.2-0.30.2-0.0-0.0-0.1-0.10.10.10.0-0.1
Pavlov. Cond. latency score0.10.21.9-0.40.4-0.3-1.4-0.80.1-0.1-0.10.1-0.40.10.0-0.50.4-0.2-0.20.10.10.30.30.20.1
Pavlov. Cond. lever contacts0.30.43.3-0.30.1-0.0-1.8-1.1-0.20.20.2-0.2-0.60.40.4-0.90.7-0.5-0.50.50.60.70.70.60.6
Pavlov. Cond. magazine entry number0.00.00.40.3-0.30.20.60.4-0.10.10.1-0.00.10.10.20.2-0.10.10.00.20.1-0.0-0.00.10.2
Pavlov. Cond. intertrial magazine entries0.20.30.9-0.1-0.00.2-0.1-0.4-0.50.30.3-0.3-0.50.80.5-0.50.6-0.8-0.80.50.70.50.50.61.0
Pavlov. Cond. lever-magazine prob. diff.0.20.21.7-0.60.6-0.5-1.3-0.80.3-0.3-0.30.3-0.40.1-0.3-0.40.3-0.1-0.1-0.20.00.10.10.1-0.1
Pavlov. Cond. response bias0.10.21.3-0.60.6-0.5-1.1-0.60.4-0.3-0.30.3-0.2-0.1-0.4-0.30.10.10.1-0.3-0.10.00.0-0.1-0.3
Pavlov. Cond. lever latency2.02.88.0-2.82.6-2.2-2.2-2.41.2-1.4-1.41.4-2.42.0-0.3-1.81.3-1.2-1.20.21.21.01.11.00.8
Pavlov. Cond. magazine entry latency0.91.34.52.1-2.01.81.31.3-1.21.31.3-1.31.5-1.10.60.9-0.60.50.50.3-0.5-0.4-0.4-0.4-0.2
Pavlov. Cond. change in total contacts0.71.86.02.4-2.31.91.81.9-1.11.31.3-1.21.8-1.50.51.3-1.00.90.80.1-0.8-0.6-0.6-0.6-0.7
Pavlov. Cond. index score1.42.27.52.7-2.62.21.82.0-1.31.51.5-1.52.0-1.70.61.4-1.00.90.90.2-0.8-0.6-0.6-0.6-0.6
Pavlov. Cond. latency score1.52.37.42.7-2.52.21.92.1-1.21.41.4-1.32.2-1.80.41.5-1.11.11.10.0-1.0-0.8-0.8-0.8-0.8
Pavlov. Cond. lever contacts1.72.57.72.8-2.52.22.02.2-1.21.41.4-1.42.3-1.90.31.6-1.21.11.1-0.1-1.1-0.9-0.9-0.9-0.7
Pavlov. Cond. magazine entry number1.11.43.6-1.91.6-1.4-1.5-1.70.6-0.7-0.70.7-1.81.60.1-1.41.1-1.2-1.20.41.11.01.00.90.7
Pavlov. Cond. intertrial magazine entries0.81.92.90.7-1.01.4-0.7-0.9-1.61.71.7-1.7-0.71.11.6-1.21.5-1.5-1.61.61.51.41.41.31.5
Pavlov. Cond. lever-magazine prob. diff.1.52.37.62.8-2.52.21.92.1-1.31.51.5-1.52.1-1.80.51.5-1.01.01.00.1-0.9-0.8-0.8-0.7-0.7
Pavlov. Cond. response bias1.82.57.62.8-2.52.21.92.2-1.21.41.4-1.42.3-1.90.31.6-1.21.11.1-0.1-1.1-1.0-1.0-0.9-0.7
Time in closed arm before self-admin0.40.72.31.5-1.51.4-0.5-0.3-1.21.11.1-1.10.5-0.41.0-0.40.1-0.3-0.30.80.40.40.40.50.6
Time in closed arm after self-admin1.31.53.00.20.2-0.40.80.81.0-0.9-0.90.91.4-1.5-1.41.1-1.71.51.5-1.5-1.6-1.6-1.6-1.6-0.9
Time in open arm before self-admin0.50.72.3-1.51.5-1.50.30.31.1-1.2-1.21.2-0.70.6-0.80.4-0.10.20.2-0.6-0.1-0.3-0.3-0.3-0.4
Time in open arm after self-admin1.82.03.50.4-0.81.0-0.5-0.5-1.61.41.4-1.5-1.11.41.8-1.01.9-1.6-1.61.81.81.71.81.71.3
Bone: periosteal estimation0.20.50.80.20.0-0.20.70.70.3-0.5-0.50.50.8-0.9-0.70.8-0.80.80.8-0.8-0.9-0.8-0.8-0.9-0.6
Bone: periosteal perimeter0.10.30.70.2-0.0-0.00.20.50.2-0.1-0.10.10.7-0.8-0.60.6-0.60.50.5-0.7-0.8-0.7-0.7-0.8-0.5
Bone: post-yield work0.30.51.3-0.20.00.2-1.1-1.1-0.50.40.4-0.4-0.70.60.6-0.90.9-0.6-0.60.70.80.70.70.80.9
Progressive ratio test 1 active lever presses0.10.20.7-0.80.8-0.7-0.1-0.10.5-0.4-0.40.4-0.40.4-0.50.10.2-0.4-0.4-0.3-0.1-0.0-0.0-0.1-0.4
Progressive ratio test 1 breakpoint0.10.21.0-1.01.0-0.8-0.1-0.20.6-0.5-0.50.5-0.50.5-0.5-0.00.3-0.4-0.4-0.3-0.10.00.0-0.1-0.4
Progressive ratio test 1 inactive lever presses0.00.10.4-0.10.00.10.50.4-0.20.10.1-0.1-0.30.50.20.10.6-0.3-0.30.20.30.30.30.2-0.2
Progressive ratio test 2 active lever presses0.10.10.4-0.40.3-0.10.3-0.1-0.10.10.1-0.1-0.40.50.1-0.30.5-0.3-0.30.20.30.30.30.20.7
Progressive ratio test 2 breakpoint0.10.10.4-0.40.3-0.10.3-0.1-0.10.00.0-0.0-0.40.50.1-0.30.5-0.3-0.30.20.30.30.30.20.7
Progressive ratio test 2 inactive lever presses0.00.00.20.1-0.10.20.40.2-0.10.10.1-0.10.20.2-0.0-0.10.40.10.1-0.0-0.1-0.0-0.0-0.20.4
Incentive Sensitization - Responses0.10.21.20.7-0.70.71.10.8-0.50.40.4-0.40.5-0.30.20.4-0.10.40.40.1-0.1-0.1-0.1-0.20.6
Incentive Sensitization - Breakpoint0.10.31.20.9-0.80.81.10.8-0.60.50.5-0.50.6-0.30.30.3-0.10.30.30.2-0.0-0.1-0.1-0.20.7
Sum of active levers in priming session hrs 5-60.30.22.00.8-0.80.51.40.7-0.40.20.2-0.20.6-0.40.20.4-0.20.30.30.1-0.2-0.0-0.0-0.1-0.1
Progressive ratio1.13.46.20.5-1.01.4-1.0-1.9-1.81.71.7-1.7-1.42.02.1-2.22.5-2.1-2.12.11.92.02.02.11.9
Food seeking constrained by brief footshock0.10.10.5-0.50.5-0.4-0.6-0.70.3-0.2-0.20.2-0.40.4-0.2-0.60.5-0.1-0.1-0.10.10.10.10.10.6
Seeking ratio, punishment vs. effort0.71.53.1-0.10.4-0.70.21.21.2-1.0-1.01.01.1-1.6-1.41.4-1.81.51.5-1.4-1.3-1.4-1.4-1.5-1.0
Retroperitoneal fat weight0.52.13.71.3-1.61.6-1.3-0.9-1.71.61.6-1.6-0.50.71.9-1.31.4-1.2-1.31.81.41.61.61.51.7
Reaction time number correct0.20.71.50.6-0.40.31.11.00.3-0.2-0.20.21.1-1.2-0.71.1-1.01.11.1-0.8-1.1-1.0-1.0-1.0-0.6
Reaction time mean minus median0.42.77.72.6-2.31.72.82.6-1.00.90.9-0.82.4-2.00.12.0-1.51.41.4-0.3-1.2-1.0-1.2-1.2-1.1
Reaction time mean minus median AUC0.32.26.52.5-2.31.72.52.3-1.11.11.1-1.02.1-1.70.21.7-1.31.01.0-0.1-0.9-0.9-1.0-0.9-0.7
Reaction time num false alarms0.61.01.30.3-0.50.8-0.7-1.0-1.21.01.0-1.0-0.70.91.1-1.01.1-1.1-1.11.11.21.01.01.10.9
Reaction time num false alarms AUC0.51.22.00.5-0.71.1-0.6-0.9-1.41.21.2-1.3-0.71.01.3-1.11.2-1.2-1.21.31.31.11.11.21.2
Reaction time trials correct on left0.20.71.50.6-0.40.31.11.00.3-0.2-0.20.21.1-1.2-0.71.1-1.01.11.1-0.8-1.1-1.0-1.0-1.0-0.6
Reaction time trials on left0.30.91.80.7-0.50.31.21.20.3-0.2-0.20.21.3-1.4-0.71.2-1.11.31.2-0.9-1.2-1.1-1.1-1.1-0.7
Reaction time mean0.30.62.41.5-1.51.20.40.7-1.01.11.1-1.10.7-0.50.90.2-0.10.00.00.70.10.40.30.20.0
Reaction time mean AUC0.20.41.11.0-1.10.80.00.2-0.80.90.9-0.90.2-0.10.9-0.20.2-0.2-0.20.80.40.60.50.40.1
Median of all reaction times0.40.71.41.0-1.21.0-0.4-0.1-1.01.21.2-1.10.00.11.1-0.40.5-0.5-0.51.00.60.80.80.70.5
Reaction time omissions1.82.96.31.4-0.90.21.22.20.6-0.6-0.60.72.3-2.5-1.12.2-2.12.22.2-1.4-2.1-1.9-2.0-1.8-2.1
Reaction time false alarm rate1.31.72.70.3-0.71.0-0.9-1.2-1.51.31.3-1.3-1.01.31.5-1.31.5-1.6-1.61.51.61.41.41.51.4
Reaction time premature initiation rate0.50.72.51.6-1.41.00.61.2-0.70.60.6-0.61.4-1.30.11.0-0.70.70.7-0.1-0.6-0.5-0.5-0.5-0.4
Reaction time premature initiations0.51.63.81.6-1.30.91.31.8-0.30.10.1-0.22.0-1.9-0.51.6-1.41.51.4-0.8-1.3-1.2-1.3-1.2-0.8
Std. dev. reaction times0.41.44.42.1-1.91.31.71.8-0.90.90.9-0.81.7-1.40.31.3-1.00.90.90.0-0.7-0.5-0.6-0.7-0.7
Reaction time trials completed0.30.91.80.7-0.50.31.21.20.3-0.2-0.20.21.3-1.4-0.71.2-1.11.31.2-0.9-1.2-1.1-1.1-1.1-0.7
Reaction time trials AUC0.20.91.80.7-0.50.41.21.10.2-0.2-0.20.21.3-1.4-0.71.1-1.11.21.2-0.8-1.1-1.0-1.1-1.0-0.6
Run reversals in cocaine runway, females0.20.23.3-0.40.4-0.4-1.8-0.50.4-0.3-0.30.3-0.2-0.1-0.2-0.10.10.10.1-0.2-0.10.00.00.1-0.5
Run reversals in cocaine runway, males0.20.20.9-1.00.9-0.60.4-0.10.3-0.2-0.20.2-0.50.6-0.40.10.5-0.2-0.2-0.2-0.0-0.1-0.1-0.1-0.8
Latency to leave start box in cocaine runway1.11.52.2-0.71.0-1.11.41.41.3-1.3-1.31.30.6-0.6-1.51.4-0.71.21.2-1.4-1.3-1.4-1.3-1.2-1.5
Latency to leave start box in cocaine runway, F0.30.40.9-0.80.9-0.80.20.20.8-0.8-0.80.8-0.10.0-0.80.40.00.50.5-0.7-0.5-0.6-0.5-0.5-0.6
Latency to leave start box in cocaine runway, M1.51.43.60.20.1-0.31.91.90.9-0.7-0.70.71.3-1.0-1.21.8-1.01.21.2-1.2-1.4-1.4-1.4-1.4-1.5
Std. dev. time between licks in bursts0.40.71.4-0.1-0.10.3-0.7-1.0-0.70.50.5-0.4-0.80.90.8-1.01.0-1.1-1.20.91.00.90.90.91.1
Total sessions with >9 infusions0.20.20.60.7-0.70.70.80.7-0.50.50.5-0.60.5-0.10.20.60.3-0.3-0.30.1-0.1-0.2-0.2-0.1-0.6
Short access day 1 total inactive lever presses0.30.72.3-1.51.5-1.2-0.8-0.90.9-0.9-0.90.9-1.01.1-0.5-0.60.9-0.2-0.2-0.30.10.30.30.2-0.1
Short access day 10 total inactive lever presses0.10.71.40.3-0.50.5-1.1-1.2-0.70.70.7-0.8-0.40.90.8-1.10.9-0.7-0.70.80.70.80.80.71.1
Short access day 1 total infusions0.40.72.11.2-1.31.50.90.4-1.31.31.3-1.40.40.10.80.20.5-0.6-0.60.60.30.30.30.30.3
Short access day 10 total infusions0.20.31.00.9-0.91.00.70.4-0.80.90.9-0.90.5-0.00.30.30.5-0.4-0.40.2-0.0-0.00.0-0.1-0.4
Short access total infusions0.10.20.50.4-0.40.60.3-0.1-0.50.60.6-0.70.20.30.20.00.7-0.6-0.60.10.10.00.0-0.0-0.2
Short access day 1 locomotion0.10.21.2-0.50.4-0.1-0.0-0.1-0.10.10.1-0.2-0.50.80.0-0.31.1-0.5-0.50.10.40.10.10.30.2
Short access day 10 total locomotion0.20.62.21.1-0.90.71.21.5-0.20.30.3-0.31.1-0.8-0.21.2-0.10.60.6-0.4-0.7-0.8-0.8-0.7-1.0
Short access total locomotion0.30.41.8-0.1-0.00.2-0.6-0.5-0.50.50.5-0.6-0.70.90.6-0.51.3-1.0-1.00.60.80.70.70.70.0
One hour access (0.3 mA shock)0.80.91.70.6-0.30.01.31.30.4-0.4-0.40.41.3-1.0-0.91.2-0.81.11.1-1.0-1.1-1.2-1.1-1.3-1.1
Compulsive drug intake0.30.40.9-0.70.8-0.9-0.30.10.9-1.0-1.01.0-0.1-0.2-0.60.1-0.70.60.6-0.5-0.3-0.3-0.3-0.4-0.6
One hour access (shock baseline)0.30.72.00.5-0.30.11.41.30.3-0.2-0.20.21.1-0.7-0.71.2-0.40.70.7-0.8-1.0-1.0-1.0-1.0-1.0
Social response proportion0.30.40.80.7-0.80.7-0.3-0.1-0.60.90.9-0.9-0.00.10.8-0.40.4-0.4-0.40.80.30.70.60.6-0.2
Social responses0.40.51.50.4-0.2-0.00.70.90.4-0.2-0.20.20.9-0.9-0.60.9-0.90.80.8-0.7-0.9-0.8-0.8-0.8-1.2
Social time0.30.51.71.3-1.20.90.50.9-0.70.70.7-0.61.0-0.80.20.7-0.40.30.20.0-0.4-0.4-0.5-0.4-0.6
Soleus weight0.00.10.30.2-0.30.0-0.5-0.2-0.1-0.2-0.20.2-0.0-0.20.3-0.20.10.20.20.30.20.20.20.20.3
Bone: stiffness0.71.44.9-2.22.1-1.8-1.5-1.61.2-1.2-1.21.2-1.51.2-0.6-1.00.6-0.4-0.3-0.30.50.50.50.5-0.0
Tibialis anterior weight0.20.62.41.6-1.41.00.41.0-0.50.40.4-0.41.3-1.30.20.7-0.60.80.9-0.0-0.5-0.5-0.5-0.5-0.2
Time to tail flick, vehicle, before self-admin1.11.42.60.4-0.70.80.9-0.6-1.20.90.9-0.9-0.91.31.5-1.21.6-1.2-1.21.61.31.61.61.61.1
Time to tail flick, vehicle, after self-admin0.40.83.1-0.60.8-0.80.91.10.9-0.9-0.90.90.2-0.4-0.91.2-0.60.70.7-0.8-0.7-0.8-0.8-0.7-1.8
Time to tail flick, test, before self-admin1.82.04.1-0.0-0.30.5-1.7-1.7-1.11.01.0-1.0-1.21.71.4-1.92.0-1.4-1.41.51.51.61.61.62.0
Time to tail flick, test, after self-admin0.70.81.30.4-0.60.6-0.3-0.6-1.01.11.1-1.1-0.50.51.1-0.90.8-1.0-1.01.11.01.11.10.90.9
Delta time to tail flick, vehicle, before/after SA2.42.64.4-1.21.6-1.60.01.01.9-1.7-1.71.70.7-1.1-2.11.6-1.41.61.6-2.0-1.7-2.0-2.0-1.8-2.1
Delta time to tail flick, test, before/after SA0.20.20.70.5-0.40.30.70.8-0.20.20.2-0.20.5-0.8-0.00.7-0.70.20.2-0.1-0.3-0.3-0.3-0.4-0.6
Tibia length0.92.44.20.9-1.31.5-0.4-0.9-2.01.91.9-1.9-0.71.21.9-1.31.6-1.7-1.71.81.71.51.51.51.9
Ambulatory time before self-admin0.20.51.5-1.21.2-1.0-1.2-0.71.0-0.8-0.80.8-0.40.2-0.8-0.2-0.20.20.2-0.6-0.4-0.4-0.4-0.4-0.5
Ambulatory time after self-admin0.50.81.3-0.2-0.10.3-1.2-0.8-0.70.70.7-0.7-1.01.00.9-0.81.1-1.0-1.01.01.11.01.01.10.5
Bone: tissue strength0.90.92.91.7-1.61.31.21.3-0.80.90.9-0.91.4-1.10.30.9-0.70.50.60.0-0.5-0.5-0.6-0.6-0.2
Total heroin consumption0.20.20.80.9-0.80.5-0.30.2-0.40.30.3-0.20.8-0.7-0.00.2-0.10.50.5-0.1-0.3-0.2-0.2-0.50.2
Bone: trabecular number0.20.41.5-0.91.0-1.1-1.2-0.50.9-0.9-0.90.9-0.3-0.1-0.7-0.1-0.10.30.3-0.6-0.3-0.2-0.2-0.3-0.3
Bone: trabecular spacing0.81.12.61.4-1.61.50.30.1-1.51.51.5-1.50.10.21.4-0.40.7-0.9-0.91.20.80.80.80.80.9
Bone: trabecular thickness0.30.40.7-0.30.4-0.50.20.40.6-0.7-0.70.70.4-0.6-0.80.6-0.60.80.8-0.8-0.7-0.7-0.7-0.7-0.5
Bone: trabecular tissue density1.62.85.9-1.61.2-0.7-1.8-2.4-0.20.10.1-0.1-2.42.41.0-2.22.0-2.1-1.91.31.92.02.01.91.1
Water consumed over 24 hours0.61.22.2-0.71.0-1.10.70.41.3-1.5-1.51.40.6-0.7-1.50.7-1.21.21.3-1.4-1.0-1.3-1.3-1.3-0.2
Number of responses in last shaping day0.10.10.60.2-0.30.2-0.50.1-0.10.20.2-0.20.00.20.2-0.00.80.00.00.20.10.30.30.1-0.7