Hub : Genes

Lmo1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_063280885.1 0.02 0.02 5.7e-03 0 0.01 0.01 0.01 1.3e-01 2.9e-03 1.1e-02 2.1e-02
2 NAcc alternative TSS NM_139112.3 0.02 0.01 7.7e-03 0 0.01 0.01 0 2.2e-01 9.3e-03 1.8e-02 9.4e-02
3 NAcc gene expression Lmo1 0.11 0.09 3.0e-11 0.06 0.07 0.06 0.08 1.7e-09 1.0e-10 3.3e-09 6.3e-12
4 pVTA intron excision ratio chr1_172598243_172602946 0.05 0.04 8.2e-04 0.01 0.02 0.02 0.01 5.2e-02 1.3e-02 1.2e-02 1.9e-02
5 pVTA isoform ratio XM_006229968.3 0.08 0.05 9.8e-06 0.04 0.06 0.08 0.08 1.9e-04 9.6e-06 6.5e-07 8.0e-07
6 PL gene expression Lmo1 0.05 0.04 8.8e-05 0.04 0.03 0.04 0.03 7.7e-05 1.1e-04 3.6e-05 1.5e-04
7 NAcc isoform ratio NM_139112.3 0.02 0.02 3.1e-03 0.01 0.01 0.01 0.01 2.6e-03 7.6e-03 4.7e-03 6.9e-03
8 NAcc intron excision ratio chr1_172572208_172602946 0.03 0.03 3.0e-04 0.03 0.03 0.02 0.02 5.6e-05 5.9e-05 7.5e-04 1.1e-04
9 Brain gene expression Lmo1 0.04 0.03 2.8e-03 0.03 0.02 0.02 0.02 1.2e-03 4.4e-03 5.3e-03 3.2e-03
10 Adipose gene expression Lmo1 0.06 0.04 7.7e-06 0.04 0.05 0.05 0.05 7.4e-05 2.9e-06 6.5e-06 3.8e-06
11 Liver alternative TSS NM_001402442.1 0.05 0.04 2.3e-04 0.03 0.03 0.03 0.03 5.5e-04 2.6e-04 1.4e-04 3.0e-04
12 IC intron excision ratio chr1_172598243_172602946 0.07 0.06 9.3e-03 0.01 0.03 0.02 0.02 1.0e-01 2.7e-02 3.7e-02 5.2e-02
13 BLA intron excision ratio chr1_172598243_172602946 0.1 0.07 1.3e-04 0.07 0.08 0.09 0.08 8.3e-05 7.3e-05 2.8e-05 7.3e-05
14 Brain mRNA stability Lmo1 0.05 0.04 4.0e-04 0.05 0.03 0.04 0.04 2.7e-05 3.9e-04 6.4e-05 9.1e-05
15 NAcc intron excision ratio chr1_172572208_172597984 0.02 0.02 3.0e-03 0.02 0.01 0.01 0.02 4.4e-04 3.2e-03 5.2e-03 1.2e-03
16 NAcc isoform ratio XM_006229968.3 0.03 0.02 9.8e-04 0.02 0.02 0.01 0.02 4.4e-04 1.1e-03 2.2e-03 1.0e-03
17 pVTA intron excision ratio chr1_172572208_172597984 0.04 0.03 3.8e-03 0.02 0.03 0.02 0.02 1.2e-02 3.2e-03 5.6e-03 8.0e-03
18 pVTA intron excision ratio chr1_172572208_172602946 0.08 0.05 7.8e-06 0.07 0.06 0.05 0.06 3.6e-06 7.3e-06 4.4e-05 8.6e-06
19 BLA mRNA stability Lmo1 0.09 0.06 9.3e-04 0.05 0.04 0.02 0.04 1.3e-03 5.9e-03 1.9e-02 5.9e-03
20 BLA isoform ratio XM_006229968.3 0.11 0.08 2.5e-04 0.06 0.07 0.05 0.07 4.4e-04 1.9e-04 7.9e-04 1.8e-04
21 BLA intron excision ratio chr1_172572208_172602946 0.09 0.08 1.2e-03 0.06 0.05 0.04 0.05 7.3e-04 7.8e-04 2.3e-03 1.0e-03
22 Liver alternative TSS XM_063280885.1 0.03 0.02 6.9e-03 0 0.01 0.02 0.01 1.1e-01 1.7e-02 4.8e-03 2.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.10.21.4-0.50.5-0.51.20.6-0.40.50.5-0.5-0.20.1-0.30.3-0.1-0.3-0.3-0.20.0-0.00.00.0-0.1
Area under the delay curve0.40.40.9-0.70.9-0.70.0-0.2-0.90.80.8-0.80.10.1-1.0-0.50.4-0.5-0.5-0.90.70.7-0.70.60.8
BMI with tail2.17.428.25.3-5.34.6-2.0-2.43.8-3.5-3.53.52.61.92.7-1.10.2-0.1-0.12.0-0.3-0.30.4-0.4-1.1
BMI without tail2.98.930.45.4-5.55.1-2.0-2.04.4-4.1-4.14.22.21.33.2-0.6-0.40.60.62.5-1.0-0.80.8-0.9-2.1
Body weight1.35.817.84.0-4.23.9-0.5-0.83.6-3.4-3.43.41.10.43.00.2-0.91.11.12.5-1.2-1.31.3-1.4-2.1
Weight adjusted by age0.60.93.31.8-1.81.6-0.1-0.51.4-1.4-1.41.40.80.51.0-0.2-0.20.30.30.8-0.3-0.20.3-0.3-0.2
Bone surface0.10.10.8-0.50.6-0.50.90.5-0.40.40.4-0.4-0.20.0-0.40.2-0.1-0.2-0.1-0.30.10.1-0.10.1-0.1
Bone volume0.00.00.20.00.0-0.10.50.1-0.10.20.2-0.20.20.4-0.2-0.10.1-0.2-0.2-0.30.20.3-0.30.2-0.1
Breakpoint value in progressive ratio session0.91.13.00.7-0.40.2-1.6-1.4-0.20.30.3-0.41.31.5-0.8-1.41.7-1.1-1.1-0.91.01.0-1.01.10.9
Number of licking bursts0.20.40.7-0.50.7-0.7-0.6-0.6-0.80.70.7-0.70.20.3-0.8-0.70.5-0.5-0.5-0.80.50.6-0.60.60.7
Context. condit. distance diff. score1.01.24.10.8-0.50.3-2.0-1.6-0.20.20.2-0.21.51.3-0.8-1.51.4-1.0-0.9-0.91.41.2-1.21.31.1
Locomotion velocity, session 10.80.81.6-0.00.2-0.8-0.9-1.0-1.01.21.2-1.20.60.8-0.8-0.91.1-1.2-1.3-0.80.80.8-0.80.80.8
Locomotion distance, session 10.60.81.90.7-0.5-0.1-1.2-1.3-0.40.70.7-0.71.11.2-0.5-1.11.1-1.2-1.4-0.61.00.8-0.80.80.8
Locomotion velocity, session 20.60.71.70.6-0.40.0-1.2-1.1-0.30.50.5-0.51.01.1-0.5-1.01.0-1.2-1.3-0.60.80.8-0.80.90.7
Locomotion distance, session 21.72.46.42.2-1.81.4-2.5-2.40.6-0.4-0.40.42.32.0-0.3-1.91.6-1.7-1.8-0.61.31.4-1.41.40.7
Locomotion velocity, session 30.10.20.60.8-0.80.5-0.7-0.60.4-0.3-0.30.40.30.10.5-0.30.1-0.1-0.20.4-0.2-0.10.1-0.1-0.3
Locomotion distance, session 30.20.21.30.7-0.70.8-1.1-0.50.6-0.6-0.60.70.2-0.10.4-0.20.00.2-0.00.3-0.1-0.20.2-0.20.0
Stereotopy head waving bouts, day 30.20.20.7-0.70.7-0.8-0.00.2-0.60.80.8-0.8-0.3-0.1-0.30.10.1-0.2-0.1-0.20.10.0-0.00.1-0.1
Stereotopy head waving duration, day 30.10.20.40.3-0.2-0.2-0.7-0.6-0.20.40.4-0.40.50.6-0.2-0.50.5-0.6-0.4-0.20.50.3-0.30.40.0
Locomotion velocity, session 73.53.86.90.20.3-0.6-2.2-2.2-1.31.21.2-1.22.12.2-2.2-2.42.3-2.1-2.1-2.32.62.5-2.52.42.1
Locomotion distance, session 71.01.22.5-0.30.6-0.7-1.6-1.2-1.00.90.9-0.90.80.9-1.3-1.31.3-1.0-1.0-1.31.41.3-1.31.31.3
Stereotopy head waving bouts, day 70.00.00.20.0-0.00.0-0.4-0.10.10.20.2-0.20.00.2-0.0-0.00.1-0.3-0.3-0.00.1-0.00.00.00.1
Stereotopy head waving duration, day 70.30.41.31.0-1.11.1-0.3-0.11.1-0.8-0.80.80.20.20.80.2-0.30.10.10.7-0.4-0.50.5-0.4-0.5
Locomotion velocity, session 82.63.14.4-0.20.7-1.0-1.5-1.6-1.61.71.7-1.71.51.8-2.0-1.92.0-2.1-2.1-2.02.12.0-2.02.11.8
Locomotion distance, session 81.82.68.81.8-1.41.2-3.0-2.50.3-0.3-0.30.32.32.0-0.7-2.21.8-1.5-1.6-1.01.71.7-1.71.81.0
Degree of sensitization distance1.01.01.90.4-0.1-0.2-1.0-1.2-0.50.50.5-0.51.21.4-1.0-1.31.2-1.2-1.0-1.11.31.3-1.31.30.9
Degree of sensitization stereotypy0.10.10.50.5-0.50.5-0.7-0.30.4-0.2-0.20.20.40.50.1-0.20.2-0.4-0.40.00.20.1-0.10.10.2
Conditioned locomotion0.60.71.7-1.00.8-0.70.50.9-0.20.20.2-0.3-1.3-1.30.41.0-0.80.91.00.6-0.9-1.01.0-1.0-0.3
Cocaine response after cond. corrected0.91.11.9-0.20.5-1.0-0.9-0.9-1.01.41.4-1.40.70.8-1.1-1.01.2-1.0-1.1-1.11.21.0-1.01.01.3
Cocaine response after cond. not corrected0.40.52.10.7-0.50.1-1.5-1.20.00.40.4-0.30.90.7-0.3-1.00.9-0.6-0.7-0.40.70.7-0.70.70.5
Cocaine response before conditioning0.70.82.41.4-1.51.6-1.1-0.71.4-1.4-1.41.40.60.20.8-0.3-0.20.30.30.6-0.3-0.10.1-0.1-0.9
Saline control response1.82.54.91.0-1.31.80.30.81.9-2.2-2.22.2-0.6-1.21.81.2-1.51.91.91.7-1.5-1.41.4-1.4-1.5
Bone: connectivity density0.10.11.1-0.30.3-0.31.00.3-0.30.30.3-0.30.00.3-0.30.10.0-0.4-0.4-0.30.20.2-0.20.20.0
Bone: cortical apparent density0.30.41.4-1.21.1-1.20.40.5-0.90.90.9-0.9-0.8-0.7-0.40.3-0.10.30.2-0.2-0.1-0.20.2-0.20.4
Bone: cortical area0.10.20.50.5-0.40.3-0.2-0.50.0-0.0-0.00.00.70.7-0.3-0.50.5-0.5-0.5-0.40.60.5-0.50.50.3
Bone: cortical porosity0.10.20.8-0.30.3-0.10.90.70.0-0.1-0.10.1-0.4-0.30.10.5-0.40.50.60.1-0.3-0.30.3-0.2-0.3
Bone: cortical porosity0.40.42.0-0.90.8-0.51.41.1-0.20.10.1-0.1-0.8-0.70.00.8-0.70.70.80.2-0.5-0.50.5-0.4-0.3
Bone: cortical thickness0.20.30.80.8-0.70.5-0.3-0.70.2-0.2-0.20.20.90.9-0.1-0.70.5-0.5-0.5-0.30.60.5-0.50.50.3
Bone: cortical thickness0.80.92.20.8-0.50.2-0.6-1.1-0.30.40.4-0.41.41.5-0.7-1.21.1-1.2-1.2-0.91.21.2-1.21.20.7
Bone: cortical tissue density0.30.41.3-1.11.1-1.10.40.5-0.80.80.8-0.8-0.8-0.8-0.30.4-0.10.30.2-0.1-0.2-0.30.3-0.30.3
Condit. Reinf. active minus inactive responses1.72.03.3-0.1-0.20.61.21.51.2-1.2-1.21.2-1.4-1.51.41.7-1.71.71.81.5-1.6-1.71.7-1.6-1.2
Condit. Reinf. active-inactive response ratio1.92.13.7-0.40.00.31.81.91.0-0.9-0.90.9-1.6-1.61.41.9-1.81.61.61.5-1.7-1.81.8-1.7-1.3
Condit. Reinf. active responses2.12.64.4-0.3-0.20.61.51.81.2-1.2-1.21.2-1.7-1.91.62.0-1.92.02.11.7-1.9-1.91.9-1.9-1.5
Condit. Reinf. inactive responses0.40.51.00.3-0.50.60.20.40.8-0.7-0.70.8-0.5-0.70.90.6-0.81.01.00.9-0.8-0.80.8-0.8-0.8
Incentive salience index mean1.61.93.3-0.70.30.01.61.80.7-0.6-0.60.7-1.7-1.81.21.8-1.71.71.81.4-1.6-1.71.7-1.7-1.1
Condit. Reinf. lever presses0.81.12.5-1.10.8-0.71.61.6-0.10.20.2-0.2-1.5-1.40.61.5-1.11.11.20.8-1.1-1.31.3-1.3-0.6
Condit. Reinf. active minus inactive responses0.20.30.70.5-0.60.70.20.20.8-0.7-0.70.8-0.1-0.30.70.4-0.50.60.50.6-0.5-0.50.5-0.5-0.4
Condit. Reinf. active-inactive response ratio0.10.20.4-0.0-0.10.30.10.30.5-0.5-0.50.5-0.3-0.50.40.4-0.50.60.50.4-0.4-0.40.4-0.4-0.3
Condit. Reinf. active responses0.20.31.10.9-0.91.00.0-0.10.9-0.9-0.90.90.30.10.60.1-0.30.30.20.5-0.3-0.20.2-0.2-0.3
Condit. Reinf. inactive responses0.40.62.31.5-1.41.4-0.4-0.70.9-1.0-1.00.90.90.70.5-0.40.2-0.2-0.20.30.10.1-0.10.1-0.1
Condit. Reinf. lever presses1.01.44.82.2-2.22.1-0.9-0.91.6-1.7-1.71.71.00.61.1-0.4-0.00.10.10.9-0.1-0.20.2-0.2-0.2
Condit. Reinf. lever reinforcers received0.20.30.70.6-0.70.80.1-0.00.8-0.8-0.80.80.1-0.10.50.1-0.30.40.30.5-0.3-0.30.3-0.3-0.2
Conditioned reinforcement - actives0.30.51.31.1-1.11.1-0.9-0.70.9-1.0-1.01.00.60.00.5-0.2-0.70.30.30.3-0.00.0-0.0-0.0-0.1
Conditioned reinforcement - inactives0.20.20.5-0.30.4-0.50.4-0.0-0.70.70.7-0.70.30.0-0.6-0.1-0.3-0.7-0.7-0.60.60.4-0.40.50.5
Conditioned locomotion1.21.53.40.1-0.40.70.91.11.2-1.1-1.11.1-1.1-1.41.41.3-1.91.41.41.4-1.4-1.41.4-1.3-1.5
Patch foraging indifference point 0 sec1.01.84.71.7-1.82.2-0.50.22.0-2.0-2.02.10.2-0.21.50.6-0.91.11.01.3-0.9-1.00.9-0.9-1.2
Patch foraging indifference point AUC0.10.20.4-0.00.1-0.3-0.3-0.4-0.40.60.6-0.60.30.5-0.4-0.40.5-0.6-0.6-0.40.40.3-0.30.40.6
Delay disc. indifference point, 0s delay0.10.10.40.6-0.50.40.4-0.30.1-0.1-0.10.10.50.4-0.0-0.30.1-0.3-0.3-0.10.20.1-0.10.20.4
Delay disc. indifference point, 16s delay1.01.12.3-0.60.9-1.0-0.1-0.3-1.31.21.2-1.20.70.7-1.5-0.90.8-1.1-1.1-1.51.31.3-1.31.21.0
Delay disc. indifference point, 2s delay0.20.31.0-1.00.9-0.50.30.4-0.30.40.4-0.2-0.9-0.8-0.10.3-0.60.40.40.0-0.3-0.40.4-0.40.1
Delay disc. indifference point, 24s delay0.10.10.5-0.10.10.4-0.20.20.4-0.7-0.70.6-0.1-0.4-0.00.1-0.40.70.70.0-0.00.2-0.2-0.10.2
Delay disc. indifference point, 4s delay0.70.72.4-1.41.4-1.20.10.1-1.21.51.5-1.3-0.8-0.5-0.7-0.10.0-0.4-0.5-0.50.10.1-0.10.00.2
Delay disc. indifference point, 8s delay0.30.41.2-0.00.2-0.2-0.1-0.7-0.70.40.4-0.40.60.5-0.8-0.80.5-0.5-0.5-0.80.80.8-0.80.71.1
Indifference point function ln k0.30.41.10.9-1.01.1-0.7-0.31.0-1.1-1.11.10.2-0.10.70.0-0.20.40.50.6-0.3-0.30.3-0.4-0.4
Indifference point function log k0.30.41.10.9-1.01.1-0.7-0.31.0-1.1-1.11.10.2-0.10.70.0-0.20.40.50.6-0.3-0.30.3-0.4-0.4
Patch foraging total patch changes 0 sec1.32.45.71.8-2.02.4-0.70.22.3-2.3-2.32.30.1-0.51.80.7-1.11.31.31.6-1.2-1.21.1-1.1-1.5
Patch foraging total patch changes 12 sec0.10.20.40.6-0.60.70.40.30.5-0.6-0.60.60.20.20.40.3-0.30.20.20.3-0.2-0.50.3-0.2-0.2
Patch foraging total patch changes 18 sec0.71.02.01.1-1.31.30.00.41.4-1.3-1.31.3-0.1-0.41.30.7-0.90.90.91.2-0.9-1.01.0-0.9-1.1
Patch foraging total patch changes 24 sec0.20.31.20.3-0.40.50.10.40.7-0.4-0.40.5-0.3-0.30.60.5-0.60.50.50.6-0.7-0.50.5-0.5-1.1
Patch foraging total patch changes 6 sec0.30.51.61.3-1.21.2-0.9-0.60.8-0.7-0.70.71.00.80.2-0.50.3-0.3-0.40.00.30.2-0.20.4-0.1
Patch foraging time to switch 0 sec0.40.82.4-1.51.5-1.50.90.6-1.41.31.3-1.4-0.6-0.2-0.90.10.2-0.3-0.3-0.70.20.3-0.30.30.3
Patch foraging water rate 0 sec0.10.20.50.6-0.60.7-0.6-0.20.7-0.7-0.70.70.1-0.10.50.1-0.30.50.50.5-0.2-0.40.3-0.3-0.3
Patch foraging water rate 12 sec1.02.07.32.7-2.62.3-1.9-1.81.6-1.6-1.61.61.81.30.9-1.10.6-0.3-0.30.50.40.3-0.30.3-0.1
Patch foraging water rate 18 sec0.50.82.91.4-1.21.1-1.7-1.30.7-0.8-0.80.81.20.80.1-1.00.7-0.4-0.4-0.10.60.7-0.60.50.1
Patch foraging water rate 24 sec0.60.82.61.3-1.11.0-1.6-1.50.6-0.6-0.60.61.31.0-0.1-1.10.8-0.7-0.7-0.30.80.6-0.70.60.3
Patch foraging water rate 6 sec0.10.10.6-0.0-0.10.3-0.7-0.10.3-0.4-0.40.4-0.2-0.40.20.1-0.20.30.30.2-0.1-0.30.2-0.2-0.4
Seeking ratio, delayed vs. immediate footshock0.60.72.9-1.71.7-1.5-0.40.4-1.01.11.1-1.1-0.8-0.4-0.80.10.6-0.1-0.1-0.50.30.3-0.20.2-0.1
Distance traveled before self-admin0.20.21.3-0.80.7-0.51.20.8-0.30.20.2-0.2-0.7-0.5-0.10.6-0.40.30.30.0-0.2-0.20.2-0.2-0.0
Distance traveled after self-admin0.60.71.20.4-0.60.71.00.41.0-0.9-0.90.9-0.6-0.61.10.5-1.10.90.91.1-1.0-0.80.8-1.0-0.3
Extensor digitorum longus weight0.31.02.91.3-1.10.6-0.6-1.30.0-0.1-0.10.01.51.7-0.4-1.21.1-1.4-1.4-0.61.11.0-1.01.00.7
Bone: elastic displacement0.10.10.20.2-0.10.30.2-0.10.1-0.3-0.30.30.40.3-0.3-0.20.10.00.1-0.30.30.4-0.40.40.1
Bone: elastic work0.10.20.40.5-0.30.4-0.2-0.40.2-0.3-0.30.30.60.5-0.3-0.50.3-0.2-0.2-0.30.40.5-0.50.50.1
Bone: endosteal estimation0.10.30.7-0.50.6-0.7-0.4-0.2-0.60.80.8-0.80.20.3-0.7-0.40.5-0.5-0.5-0.70.50.5-0.50.60.4
Bone: endosteal perimeter0.30.71.4-0.60.8-0.8-0.2-0.3-0.90.90.9-0.90.50.7-1.2-0.70.8-0.8-0.7-1.11.01.0-1.01.00.8
Epididymis fat weight0.10.41.51.2-1.21.0-0.5-0.40.9-0.8-0.80.70.50.40.7-0.1-0.0-0.00.00.5-0.2-0.20.2-0.1-0.6
Delta time in closed arm before/after self-admin1.91.73.40.20.2-0.3-1.4-1.5-1.00.60.6-0.71.61.3-1.5-1.51.6-1.4-1.4-1.71.71.8-1.81.80.9
Delta time in open arm before/after self-admin3.03.05.21.1-1.51.60.91.12.1-1.9-1.92.0-0.9-1.12.31.6-1.81.71.72.2-1.9-2.02.0-1.9-1.6
Diff in mean of infusions in LGA sessions0.20.21.0-0.10.2-0.4-0.2-0.6-0.40.60.6-0.60.30.3-0.5-0.60.2-0.6-0.6-0.50.40.3-0.30.41.0
Delay discount exponential model param0.40.40.90.8-0.90.60.00.20.9-0.8-0.80.7-0.00.00.90.5-0.30.40.40.9-0.6-0.60.6-0.5-0.7
Extinction: sum of active levers before priming0.10.10.3-0.20.3-0.2-0.0-0.1-0.30.40.4-0.40.10.3-0.4-0.20.5-0.4-0.4-0.40.30.3-0.30.20.0
Active lever presses in extinction session 61.21.23.10.6-0.30.1-1.1-1.7-0.30.50.5-0.51.31.6-0.9-1.81.4-1.3-1.3-1.11.21.2-1.21.21.3
Bone: final force0.30.51.4-0.30.1-0.01.21.00.3-0.3-0.30.3-0.9-0.80.71.0-0.90.70.70.8-0.9-1.01.0-0.9-0.7
Bone: final moment0.40.61.4-0.1-0.10.21.20.90.5-0.4-0.40.4-0.8-0.70.81.0-0.90.80.80.9-0.9-1.01.0-1.0-0.8
Food consumed during 24 hour testing period0.30.43.50.6-0.60.80.60.90.7-0.7-0.70.80.40.20.20.80.00.1-0.00.1-0.10.2-0.20.2-1.9
Glucose0.10.20.5-0.40.5-0.50.10.1-0.40.70.7-0.7-0.00.1-0.4-0.10.2-0.4-0.3-0.40.20.2-0.20.20.5
Heart weight0.30.51.91.3-1.41.1-0.6-0.61.1-0.9-0.90.90.60.40.8-0.2-0.10.10.10.6-0.2-0.10.2-0.2-0.6
Delay discount hyperbolic model param0.30.30.90.9-1.00.6-0.10.10.8-0.8-0.80.70.20.20.80.3-0.10.20.20.7-0.4-0.40.4-0.3-0.6
Intermittent access intake day 1-15 change0.20.40.9-0.70.8-0.90.4-0.0-1.00.90.9-0.90.1-0.0-0.8-0.1-0.1-0.7-0.7-0.70.60.6-0.60.60.1
Intermittent access intake escalation0.20.41.0-0.80.9-1.00.60.2-1.00.90.9-0.9-0.0-0.1-0.80.1-0.2-0.6-0.6-0.70.50.5-0.50.5-0.1
Intermittent access intake escalation 20.20.20.4-0.30.4-0.60.2-0.0-0.60.50.5-0.50.20.1-0.50.00.2-0.5-0.5-0.50.50.4-0.40.5-0.3
Intermitt. access day 1 inactive lever presses0.10.41.1-1.01.1-1.00.10.2-0.90.90.9-0.8-0.3-0.4-0.70.2-0.2-0.4-0.4-0.60.30.2-0.20.40.1
Intermitt. access day 15 inactive lever presses0.20.40.80.00.1-0.40.50.1-0.70.70.7-0.70.60.2-0.7-0.00.0-0.9-0.9-0.80.80.8-0.80.80.2
Intermitt. access escalation Index0.40.61.40.2-0.50.6-0.10.70.8-0.7-0.70.7-0.6-0.61.00.9-0.50.90.91.0-0.9-0.90.9-0.9-1.2
Intermittent access day 1 total infusions0.10.10.5-0.0-0.10.20.1-0.00.4-0.4-0.40.5-0.4-0.40.40.0-0.20.70.70.4-0.5-0.50.5-0.4-0.1
Intermittent access day 15 total infusions0.10.20.7-0.80.8-0.80.60.1-0.60.60.6-0.6-0.4-0.5-0.40.1-0.50.10.1-0.30.10.1-0.10.2-0.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.20.2-0.20.2-0.1-0.1-0.0-0.00.0-0.1-0.3-0.10.1-0.30.30.3-0.0-0.0-0.10.10.1-0.3
Intermittent access total infusions0.20.20.6-0.30.20.00.20.30.2-0.3-0.30.3-0.5-0.70.30.3-0.60.70.70.3-0.5-0.50.5-0.4-0.3
Intermittent access day 1 locomotion0.70.81.9-1.10.8-0.51.21.1-0.00.00.00.0-1.4-1.20.41.0-1.31.11.10.6-1.0-1.11.1-0.9-0.7
Intermittent access day 15 total locomotion0.51.02.4-0.40.10.01.41.20.4-0.5-0.50.5-1.1-1.20.91.2-1.61.11.11.0-1.1-1.11.1-1.1-1.2
Intermittent access total locomotion0.70.82.1-0.60.4-0.11.21.10.3-0.4-0.40.4-1.1-1.20.71.1-1.51.11.10.8-1.0-1.11.1-0.9-0.9
Intermittent access standard deviation0.30.61.30.4-0.10.0-0.9-0.8-0.30.20.2-0.21.10.7-0.8-0.90.5-0.8-0.8-0.91.11.1-1.11.10.7
Left kidney weight0.31.55.22.1-2.31.9-0.4-0.51.8-1.5-1.51.50.60.31.60.1-0.30.20.21.4-0.7-0.80.8-0.8-1.4
Right kidney weight0.52.17.72.8-2.82.6-0.9-1.02.1-2.0-2.01.91.20.81.5-0.3-0.1-0.0-0.11.1-0.3-0.40.4-0.4-0.9
Cocaine induced anxiety0.20.21.0-0.50.4-0.31.01.00.0-0.0-0.00.0-0.6-0.60.10.7-0.40.60.60.2-0.4-0.30.3-0.3-0.4
Post-drug Anxiety1.11.13.1-1.51.6-1.80.90.4-1.61.61.6-1.6-0.40.1-1.2-0.10.8-0.5-0.5-1.00.60.5-0.50.51.1
Baseline Anxiety0.91.02.0-1.01.1-1.3-0.4-0.7-1.41.41.4-1.40.00.6-1.1-0.71.0-1.1-1.1-1.00.90.7-0.70.71.3
Tail length0.72.86.4-0.4-0.00.61.31.91.3-1.3-1.31.3-1.8-2.01.62.0-2.12.12.01.7-2.1-1.81.8-1.9-2.5
Length with tail0.20.81.6-0.60.4-0.21.11.20.4-0.4-0.40.4-1.2-1.30.61.1-1.11.21.20.8-1.1-1.01.0-1.0-1.3
Length without tail0.20.71.7-1.31.1-1.01.31.1-0.60.50.5-0.5-1.2-1.1-0.00.9-0.60.70.70.2-0.5-0.60.6-0.7-0.3
Times rat made contact with spout0.20.21.2-0.30.3-0.31.11.0-0.30.40.4-0.3-0.2-0.1-0.10.8-0.0-0.0-0.1-0.1-0.1-0.10.1-0.0-0.8
Lifetime Intake0.10.10.50.1-0.20.4-0.10.10.4-0.5-0.50.5-0.2-0.40.30.1-0.60.70.70.3-0.3-0.30.3-0.2-0.0
Liver weight, left0.50.82.30.1-0.30.21.31.00.5-0.4-0.40.3-0.8-0.81.01.1-1.00.80.81.0-1.1-1.11.1-1.1-1.5
Liver weight, right0.20.42.5-0.30.1-0.31.60.90.00.10.1-0.1-0.6-0.40.40.8-0.60.40.40.5-0.6-0.60.6-0.6-1.1
Locomotor activity0.91.44.72.2-1.91.2-0.5-1.60.7-0.4-0.40.41.91.90.2-1.31.0-1.2-1.2-0.20.71.0-0.90.80.6
Locomotor testing distance1.01.87.42.7-2.51.9-0.8-1.71.3-1.1-1.11.12.01.80.6-1.20.8-0.9-0.80.20.50.7-0.70.60.5
Locomotor testing rearing0.30.62.51.6-1.51.0-0.4-1.00.8-0.7-0.70.71.10.90.5-0.70.4-0.4-0.40.20.20.3-0.30.20.4
Locomotion in novel chamber0.10.10.40.3-0.40.2-0.5-0.10.20.20.2-0.2-0.10.30.40.00.5-0.2-0.20.4-0.3-0.60.6-0.4-0.1
Locomotion in novel chamber post-restriction0.20.31.1-1.01.0-1.0-0.30.1-0.90.90.9-0.9-0.6-0.3-0.4-0.00.3-0.1-0.1-0.30.1-0.10.0-0.00.1
Fecal boli incidents, locomotor time 11.21.86.5-2.62.4-1.92.41.6-1.21.01.0-1.0-1.9-1.4-0.51.1-1.20.70.7-0.1-0.5-0.70.6-0.50.2
Change in fecal boli incidents, locomotor task3.83.86.60.30.3-0.7-1.7-1.9-1.41.61.6-1.62.02.1-2.1-2.22.3-2.5-2.5-2.22.32.6-2.52.31.9
Time >=10cm from walls, locomotor time 10.10.10.4-0.0-0.10.20.60.40.3-0.5-0.50.4-0.3-0.30.40.4-0.60.50.50.4-0.4-0.20.3-0.4-0.0
Bouts of movement, locomotor time 10.00.00.1-0.10.2-0.1-0.3-0.2-0.10.10.1-0.20.00.1-0.2-0.10.1-0.0-0.0-0.20.10.3-0.20.10.2
Total resting periods, locomotor time 10.30.40.7-0.50.6-0.6-0.4-0.4-0.70.70.7-0.80.20.4-0.8-0.50.5-0.5-0.5-0.80.50.7-0.70.50.7
Rest time, locomotor task time 14.05.09.2-2.32.7-2.80.5-0.4-3.02.92.9-3.00.31.0-2.9-1.51.4-2.2-2.1-2.72.22.0-1.92.12.6
Distance moved, locomotor task time 12.53.86.71.6-2.12.10.00.72.4-2.3-2.32.4-0.7-1.12.61.6-1.32.01.92.4-2.1-2.22.1-2.0-2.4
Vertical activity count, locomotor time 11.33.26.01.8-2.22.30.40.52.3-2.4-2.42.4-0.3-0.82.31.3-1.21.71.72.1-1.8-1.71.6-1.7-2.0
Time >=10cm from walls, locomotor time 20.60.93.01.3-1.10.8-1.4-1.70.3-0.4-0.40.31.31.2-0.1-1.21.0-0.6-0.6-0.30.60.7-0.60.71.3
Bouts of movement, locomotor time 20.10.10.3-0.20.10.10.40.40.10.00.00.2-0.3-0.40.20.5-0.20.30.30.2-0.3-0.30.3-0.3-0.5
Total resting periods, locomotor time 20.00.10.2-0.40.4-0.20.40.4-0.30.40.4-0.2-0.2-0.2-0.20.30.0-0.1-0.1-0.20.00.00.00.0-0.4
Rest time, locomotor task time 21.41.83.3-0.91.2-1.2-0.4-0.9-1.51.51.5-1.30.60.8-1.7-1.31.1-1.5-1.5-1.61.41.5-1.41.41.8
Distance moved, locomotor task time 21.11.33.61.7-1.91.6-0.6-0.51.6-1.5-1.51.40.30.21.50.2-0.20.70.71.3-0.8-1.21.0-0.8-0.6
Vertical activity count, locomotor time 20.10.10.40.6-0.60.40.4-0.20.4-0.6-0.60.40.20.10.40.20.10.30.30.3-0.2-0.30.2-0.1-0.1
Light reinforcement 10.00.10.80.0-0.10.20.90.60.1-0.1-0.10.2-0.20.00.20.5-0.40.10.00.3-0.2-0.30.4-0.20.0
Light reinforcement 20.20.31.21.1-1.01.10.2-0.30.6-0.7-0.70.70.90.90.1-0.30.2-0.5-0.5-0.00.20.3-0.30.4-0.3
Bone: marrow area0.20.30.7-0.60.7-0.8-0.3-0.1-0.60.90.9-0.90.10.3-0.7-0.30.5-0.5-0.5-0.70.50.5-0.50.50.4
Bone: maximum diameter0.20.30.80.8-0.60.5-0.7-0.70.2-0.2-0.20.20.90.9-0.2-0.70.6-0.7-0.7-0.40.70.6-0.60.60.3
Bone: maximum force0.10.20.7-0.50.4-0.20.80.80.1-0.0-0.00.0-0.7-0.50.20.7-0.60.40.40.3-0.5-0.50.5-0.5-0.4
Bone: maximum moment0.10.20.5-0.20.10.10.70.70.4-0.3-0.30.3-0.5-0.40.40.6-0.60.50.50.4-0.5-0.50.5-0.5-0.4
Mean time between licks in bursts0.10.20.6-0.40.3-0.10.80.2-0.0-0.2-0.20.2-0.6-0.40.20.2-0.60.50.60.3-0.4-0.40.4-0.50.5
Mean num. licks in bursts0.30.51.50.2-0.40.41.21.20.5-0.4-0.40.4-0.4-0.40.71.2-0.50.40.40.7-0.6-0.60.6-0.6-1.2
Cd content in liver1.11.24.2-2.01.9-1.51.41.1-1.20.90.9-0.9-1.6-1.3-0.40.7-0.80.80.8-0.1-0.7-0.70.7-0.70.6
Co content in liver0.40.51.0-0.20.4-0.40.10.4-0.80.70.7-0.70.60.7-0.90.00.9-0.7-0.7-0.91.00.8-0.80.8-0.4
Cu content in liver3.03.55.50.8-1.31.61.51.22.0-2.1-2.12.1-1.3-1.42.31.6-2.22.12.12.3-2.1-2.22.2-2.2-1.6
Fe content in liver0.00.00.1-0.10.10.1-0.2-0.10.0-0.2-0.20.2-0.3-0.40.20.0-0.20.30.30.2-0.2-0.30.3-0.2-0.1
K content in liver1.11.11.60.3-0.60.81.10.71.1-1.3-1.31.3-0.7-0.81.20.9-1.21.21.21.2-1.1-1.31.3-1.2-0.6
Mg content in liver2.82.87.32.0-2.32.50.80.22.3-2.7-2.72.70.2-0.22.00.7-1.21.21.21.7-1.1-1.11.1-1.1-1.3
Mn content in liver1.61.72.90.3-0.71.00.40.81.5-1.3-1.31.3-1.0-1.41.61.1-1.61.71.71.6-1.5-1.51.5-1.5-1.2
Na content in liver0.10.20.40.6-0.50.5-0.5-0.60.1-0.3-0.30.30.60.5-0.1-0.50.4-0.3-0.3-0.20.40.4-0.40.40.2
Rb content in liver3.84.58.0-0.80.10.41.51.51.4-1.4-1.41.4-2.6-2.82.21.9-2.82.82.82.5-2.8-2.82.8-2.8-1.1
Se content in liver0.81.02.1-0.50.20.20.30.80.7-0.7-0.70.7-1.2-1.50.91.0-1.21.41.41.0-1.2-1.21.2-1.2-0.5
Sr content in liver1.51.35.51.2-0.90.7-2.4-1.50.00.10.1-0.11.61.3-0.6-1.31.4-1.2-1.2-0.81.21.2-1.21.20.6
Zn content in liver1.61.75.72.4-2.42.3-0.4-0.61.8-2.0-2.02.01.10.91.2-0.2-0.10.20.20.9-0.1-0.20.2-0.2-0.8
Bone: minimum diameter0.50.91.6-0.40.7-0.8-0.7-0.7-0.91.01.0-1.00.70.8-1.2-1.01.0-1.0-1.1-1.21.11.1-1.11.11.0
Time in familiar zone, hab. session 11.81.73.70.20.2-0.2-1.9-1.7-0.80.50.5-0.51.41.1-1.5-1.71.5-1.2-1.2-1.61.71.7-1.71.71.4
Time in novel zone, hab. session 10.20.21.3-0.40.3-0.61.10.6-0.30.60.6-0.6-0.30.10.00.4-0.2-0.1-0.10.1-0.2-0.20.2-0.2-0.2
Total zone transitions, hab. session 10.40.51.50.9-1.01.2-0.8-0.11.2-1.0-1.01.00.2-0.10.70.2-0.30.40.30.6-0.5-0.40.4-0.3-0.6
Total locomotion distance, hab. session 10.30.51.30.3-0.41.0-0.50.21.0-1.1-1.11.1-0.2-0.60.50.3-0.60.70.60.5-0.7-0.40.4-0.4-0.7
Locomotion velocity, hab. session 10.81.12.60.6-0.81.4-0.30.51.5-1.6-1.61.6-0.4-0.91.10.7-1.11.11.01.0-1.1-0.80.8-0.8-1.2
Time in familiar zone, hab. session 20.80.83.01.4-1.41.6-1.7-1.11.1-1.3-1.31.30.80.20.5-0.60.2-0.0-0.00.30.10.1-0.10.1-0.1
Time in novel zone, hab. session 20.10.10.50.1-0.0-0.20.70.2-0.20.30.3-0.30.10.5-0.10.00.1-0.1-0.1-0.10.10.1-0.10.1-0.1
Total zone transitions, hab. session 20.70.93.21.7-1.81.5-0.9-0.71.4-1.1-1.11.10.70.41.1-0.2-0.10.1-0.00.8-0.2-0.30.3-0.3-0.6
Total locomotion distance, hab. session 20.60.82.81.7-1.71.7-0.6-0.61.4-1.3-1.31.30.80.60.8-0.3-0.10.0-0.00.6-0.1-0.10.1-0.0-0.6
Locomotion velocity, hab. session 20.60.92.71.6-1.61.6-0.4-0.41.5-1.3-1.31.30.60.31.0-0.0-0.30.30.20.8-0.3-0.30.3-0.3-0.8
Novel to familiar place preference ratio2.62.85.4-0.60.20.22.32.21.0-1.0-1.01.0-1.9-1.81.52.1-2.12.01.91.7-2.0-1.91.9-1.9-2.0
Novelty place preference1.61.73.8-0.60.20.01.91.80.8-0.7-0.70.7-1.5-1.41.11.7-1.61.51.41.3-1.6-1.41.4-1.4-1.6
Time in novel zone, NPP test1.21.33.2-0.50.10.11.81.60.7-0.7-0.70.7-1.2-1.11.01.5-1.41.31.21.1-1.4-1.21.2-1.2-1.4
Total zone transitions, NPP test0.30.41.20.9-0.80.5-1.1-0.90.3-0.1-0.10.10.90.8-0.1-0.70.6-0.5-0.6-0.30.60.5-0.50.60.3
Total locomotion distance, NPP test1.11.53.71.8-1.51.4-1.9-1.80.7-0.7-0.70.71.91.5-0.3-1.51.1-1.0-1.1-0.51.01.2-1.21.20.3
Locomotion velocity, NPP test1.01.43.41.8-1.51.4-1.8-1.70.8-0.8-0.80.81.81.4-0.2-1.41.0-0.8-0.9-0.40.91.1-1.11.10.2
Intraocular pressure0.10.20.7-0.60.5-0.40.90.7-0.30.10.1-0.1-0.5-0.30.00.5-0.40.30.30.1-0.3-0.20.2-0.3-0.6
Delta distance traveled before/after self-admin0.70.81.71.2-1.31.2-0.1-0.31.3-1.2-1.21.20.1-0.21.20.1-0.80.60.61.1-0.8-0.70.7-0.8-0.7
Delta ambulatory time before/after self-admin0.40.51.00.5-0.70.60.00.01.0-0.8-0.80.8-0.4-0.41.00.3-0.70.70.71.0-0.9-0.90.9-0.9-0.8
Parametrial fat weight0.71.62.71.3-1.51.61.30.71.6-1.6-1.61.6-0.3-0.51.61.0-1.11.11.11.5-1.1-1.11.2-1.2-1.6
Pavlov. Cond. lever latency0.60.74.60.9-0.70.5-2.1-1.40.2-0.1-0.10.11.00.7-0.2-1.10.9-0.7-0.7-0.40.70.8-0.80.70.6
Pavlov. Cond. magazine entry latency0.10.10.30.3-0.20.10.1-0.20.10.00.00.00.40.6-0.2-0.30.3-0.3-0.3-0.30.40.3-0.30.40.4
Pavlov. Cond. change in total contacts0.91.03.3-1.81.8-1.51.81.4-1.11.11.1-1.1-1.1-0.6-0.70.8-0.40.20.2-0.4-0.1-0.20.2-0.20.3
Pavlov. Cond. index score0.10.11.3-0.40.4-0.31.20.6-0.20.20.2-0.1-0.20.1-0.20.3-0.20.00.0-0.10.1-0.10.1-0.00.1
Pavlov. Cond. latency score0.10.21.9-0.40.4-0.31.40.8-0.10.10.1-0.1-0.4-0.10.00.5-0.40.20.20.1-0.1-0.30.3-0.2-0.1
Pavlov. Cond. lever contacts0.30.43.2-0.30.1-0.01.81.10.2-0.2-0.20.2-0.6-0.40.40.9-0.70.50.50.5-0.6-0.70.7-0.6-0.6
Pavlov. Cond. magazine entry number0.00.00.40.3-0.30.2-0.6-0.40.1-0.1-0.10.00.1-0.10.2-0.20.1-0.1-0.00.2-0.10.0-0.0-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.20.30.9-0.1-0.00.20.10.40.5-0.3-0.30.3-0.5-0.80.50.5-0.60.80.80.5-0.7-0.50.5-0.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.21.7-0.60.6-0.51.30.8-0.30.30.3-0.3-0.4-0.1-0.30.4-0.30.10.1-0.2-0.0-0.10.1-0.10.1
Pavlov. Cond. response bias0.10.21.3-0.60.6-0.51.10.6-0.40.30.3-0.3-0.20.1-0.40.3-0.1-0.1-0.1-0.30.1-0.00.00.10.3
Pavlov. Cond. lever latency2.02.88.0-2.82.6-2.32.22.4-1.21.41.4-1.4-2.4-2.0-0.31.8-1.31.21.20.2-1.2-1.01.0-1.0-0.8
Pavlov. Cond. magazine entry latency1.11.34.52.1-2.01.8-1.3-1.31.2-1.3-1.31.31.51.10.6-0.90.6-0.5-0.50.30.50.4-0.40.40.2
Pavlov. Cond. change in total contacts1.11.86.02.4-2.31.9-1.8-1.91.1-1.3-1.31.21.81.50.5-1.31.0-0.9-0.80.10.80.6-0.60.60.7
Pavlov. Cond. index score1.72.27.52.7-2.62.2-1.8-2.01.3-1.5-1.51.52.01.70.6-1.41.0-0.9-0.90.20.80.6-0.60.60.6
Pavlov. Cond. latency score1.82.37.42.7-2.52.2-1.9-2.11.2-1.4-1.41.32.21.80.4-1.51.1-1.1-1.10.01.00.8-0.80.80.8
Pavlov. Cond. lever contacts1.82.57.72.8-2.52.2-2.0-2.21.2-1.4-1.41.42.31.90.3-1.61.2-1.1-1.1-0.11.10.9-0.90.90.7
Pavlov. Cond. magazine entry number1.21.43.6-1.91.6-1.41.51.7-0.60.70.7-0.7-1.8-1.60.11.4-1.11.21.20.4-1.1-1.01.0-0.9-0.7
Pavlov. Cond. intertrial magazine entries1.21.92.90.7-1.01.40.70.91.6-1.7-1.71.7-0.7-1.11.61.2-1.51.51.61.6-1.5-1.41.4-1.3-1.5
Pavlov. Cond. lever-magazine prob. diff.1.82.37.62.8-2.52.2-1.9-2.11.3-1.5-1.51.52.11.80.5-1.51.0-1.0-1.00.10.90.8-0.80.70.7
Pavlov. Cond. response bias1.82.57.62.8-2.52.2-1.9-2.21.2-1.4-1.41.42.31.90.3-1.61.2-1.1-1.1-0.11.11.0-1.00.90.7
Time in closed arm before self-admin0.50.72.31.5-1.51.40.50.31.2-1.1-1.11.10.50.41.00.4-0.10.30.30.8-0.4-0.40.4-0.5-0.6
Time in closed arm after self-admin1.41.53.00.20.2-0.4-0.8-0.8-1.00.90.9-0.91.41.5-1.4-1.11.7-1.5-1.5-1.51.61.6-1.61.60.9
Time in open arm before self-admin0.60.72.3-1.51.5-1.5-0.3-0.3-1.11.21.2-1.2-0.7-0.6-0.8-0.40.1-0.2-0.2-0.60.10.3-0.30.30.4
Time in open arm after self-admin1.82.03.50.4-0.81.00.50.51.6-1.4-1.41.5-1.1-1.41.81.0-1.91.61.61.8-1.8-1.71.7-1.7-1.3
Bone: periosteal estimation0.20.40.80.20.0-0.2-0.7-0.7-0.30.50.5-0.50.80.9-0.7-0.80.8-0.8-0.8-0.80.90.8-0.80.90.6
Bone: periosteal perimeter0.20.30.70.2-0.0-0.0-0.2-0.5-0.20.10.1-0.10.70.8-0.6-0.60.6-0.5-0.5-0.70.80.7-0.70.80.5
Bone: post-yield work0.30.51.3-0.20.00.21.11.10.5-0.4-0.40.4-0.7-0.60.60.9-0.90.60.60.7-0.8-0.70.7-0.8-0.9
Progressive ratio test 1 active lever presses0.10.20.7-0.80.8-0.70.10.1-0.50.40.4-0.4-0.4-0.4-0.5-0.1-0.20.40.4-0.30.10.0-0.00.10.4
Progressive ratio test 1 breakpoint0.20.21.0-1.01.0-0.80.10.2-0.60.50.5-0.5-0.5-0.5-0.50.0-0.30.40.4-0.30.1-0.00.00.10.4
Progressive ratio test 1 inactive lever presses0.10.10.4-0.10.00.1-0.5-0.40.2-0.1-0.10.1-0.3-0.50.2-0.1-0.60.30.30.2-0.3-0.30.3-0.20.2
Progressive ratio test 2 active lever presses0.10.10.4-0.40.3-0.1-0.30.10.1-0.1-0.10.1-0.4-0.50.10.3-0.50.30.30.2-0.3-0.30.3-0.2-0.7
Progressive ratio test 2 breakpoint0.10.10.4-0.40.3-0.1-0.30.10.1-0.0-0.00.0-0.4-0.50.10.3-0.50.30.30.2-0.3-0.30.3-0.2-0.7
Progressive ratio test 2 inactive lever presses0.00.00.20.1-0.10.2-0.4-0.20.1-0.1-0.10.10.2-0.2-0.00.1-0.4-0.1-0.1-0.00.10.0-0.00.2-0.4
Incentive Sensitization - Responses0.20.21.20.7-0.70.7-1.1-0.80.5-0.4-0.40.40.50.30.2-0.40.1-0.4-0.40.10.10.1-0.10.2-0.6
Incentive Sensitization - Breakpoint0.20.31.20.9-0.80.8-1.1-0.80.6-0.5-0.50.50.60.30.3-0.30.1-0.3-0.30.20.00.1-0.10.2-0.7
Sum of active levers in priming session hrs 5-60.30.22.00.8-0.80.5-1.4-0.70.4-0.2-0.20.20.60.40.2-0.40.2-0.3-0.30.10.20.0-0.00.10.1
Progressive ratio2.23.46.20.5-1.01.41.01.91.8-1.7-1.71.7-1.4-2.02.12.2-2.52.12.12.1-1.9-2.02.0-2.1-1.9
Food seeking constrained by brief footshock0.10.10.5-0.50.5-0.40.60.7-0.30.20.2-0.2-0.4-0.4-0.20.6-0.50.10.1-0.1-0.1-0.10.1-0.1-0.6
Seeking ratio, punishment vs. effort1.01.53.1-0.10.4-0.7-0.3-1.2-1.21.01.0-1.01.11.6-1.4-1.41.8-1.5-1.5-1.41.31.4-1.41.51.0
Retroperitoneal fat weight0.52.13.71.3-1.61.61.30.91.7-1.6-1.61.6-0.5-0.71.91.3-1.41.21.31.8-1.4-1.61.6-1.5-1.7
Reaction time number correct0.40.71.50.6-0.40.3-1.1-1.0-0.30.20.2-0.21.11.2-0.7-1.11.0-1.1-1.1-0.81.11.0-1.01.00.6
Reaction time mean minus median1.12.77.72.6-2.31.7-2.8-2.61.0-0.9-0.90.82.42.00.1-2.01.5-1.4-1.4-0.31.21.0-1.11.21.1
Reaction time mean minus median AUC0.92.26.42.5-2.31.7-2.5-2.31.1-1.1-1.11.02.11.70.2-1.71.3-1.0-1.0-0.10.90.9-1.00.90.7
Reaction time num false alarms0.70.91.30.3-0.50.80.71.01.2-1.0-1.01.0-0.7-0.91.11.0-1.11.11.11.1-1.2-1.01.0-1.1-0.9
Reaction time num false alarms AUC0.81.22.00.5-0.71.10.60.91.4-1.2-1.21.3-0.7-1.01.31.1-1.21.21.21.3-1.3-1.11.1-1.2-1.2
Reaction time trials correct on left0.40.71.50.6-0.40.3-1.1-1.0-0.30.20.2-0.21.11.2-0.7-1.11.0-1.1-1.1-0.81.11.0-1.01.00.6
Reaction time trials on left0.50.91.80.7-0.50.3-1.2-1.2-0.30.20.2-0.21.31.4-0.7-1.21.1-1.3-1.2-0.91.21.1-1.11.10.7
Reaction time mean0.40.62.41.5-1.51.2-0.4-0.71.0-1.1-1.11.10.70.50.9-0.20.1-0.0-0.00.7-0.1-0.40.3-0.2-0.0
Reaction time mean AUC0.20.41.11.0-1.10.8-0.0-0.20.8-0.9-0.90.90.20.10.90.2-0.20.20.20.8-0.4-0.60.5-0.4-0.1
Median of all reaction times0.50.71.41.0-1.21.00.40.11.0-1.2-1.21.10.0-0.11.10.4-0.50.50.51.0-0.6-0.80.8-0.7-0.5
Reaction time omissions2.02.96.31.4-0.90.2-1.2-2.2-0.60.60.6-0.72.32.5-1.1-2.22.1-2.2-2.2-1.42.11.9-2.01.82.1
Reaction time false alarm rate1.31.72.70.3-0.71.00.91.21.5-1.3-1.31.3-1.0-1.31.51.3-1.51.61.61.5-1.6-1.41.4-1.5-1.4
Reaction time premature initiation rate0.50.72.51.6-1.41.0-0.6-1.20.7-0.6-0.60.61.41.30.1-1.00.7-0.7-0.7-0.10.60.5-0.50.50.4
Reaction time premature initiations0.91.63.81.6-1.30.9-1.3-1.80.3-0.1-0.10.22.01.9-0.5-1.61.4-1.5-1.4-0.81.31.2-1.31.20.8
Std. dev. reaction times0.81.44.42.1-1.91.3-1.7-1.80.9-0.9-0.90.81.71.40.3-1.31.0-0.9-0.90.00.70.5-0.60.70.7
Reaction time trials completed0.50.91.80.7-0.50.3-1.2-1.2-0.30.20.2-0.21.31.4-0.7-1.21.1-1.3-1.2-0.91.21.1-1.11.10.7
Reaction time trials AUC0.40.91.80.7-0.50.4-1.2-1.1-0.20.20.2-0.21.31.4-0.7-1.11.1-1.2-1.2-0.81.11.0-1.11.00.6
Run reversals in cocaine runway, females0.20.23.3-0.40.4-0.41.80.5-0.40.30.3-0.3-0.20.1-0.20.1-0.1-0.1-0.1-0.20.1-0.00.0-0.10.5
Run reversals in cocaine runway, males0.20.20.9-1.00.9-0.6-0.40.1-0.30.20.2-0.2-0.5-0.6-0.4-0.1-0.50.20.2-0.20.00.1-0.10.10.8
Latency to leave start box in cocaine runway1.31.52.2-0.71.0-1.1-1.4-1.4-1.31.31.3-1.30.60.6-1.5-1.40.7-1.2-1.2-1.41.31.4-1.31.21.5
Latency to leave start box in cocaine runway, F0.30.40.9-0.80.9-0.8-0.2-0.2-0.80.80.8-0.8-0.1-0.0-0.8-0.4-0.0-0.5-0.5-0.70.50.6-0.50.50.6
Latency to leave start box in cocaine runway, M1.51.43.60.20.1-0.3-1.9-1.9-0.90.70.7-0.71.31.0-1.2-1.81.0-1.2-1.2-1.21.41.4-1.41.41.5
Std. dev. time between licks in bursts0.50.71.4-0.1-0.10.30.71.00.7-0.5-0.50.4-0.8-0.90.81.0-1.01.11.20.9-1.0-0.90.9-0.9-1.1
Total sessions with >9 infusions0.20.20.60.7-0.70.7-0.8-0.70.5-0.5-0.50.60.50.10.2-0.6-0.30.30.30.10.10.2-0.20.10.6
Short access day 1 total inactive lever presses0.50.72.3-1.51.5-1.20.80.9-0.90.90.9-0.9-1.0-1.1-0.50.6-0.90.20.2-0.3-0.1-0.30.3-0.20.1
Short access day 10 total inactive lever presses0.30.71.40.3-0.50.51.11.20.7-0.7-0.70.8-0.4-0.90.81.1-0.90.70.70.8-0.7-0.80.8-0.7-1.1
Short access day 1 total infusions0.50.72.11.2-1.31.5-0.8-0.41.3-1.3-1.31.40.4-0.10.8-0.2-0.50.60.60.6-0.3-0.30.3-0.3-0.3
Short access day 10 total infusions0.30.31.00.9-0.91.0-0.7-0.40.8-0.9-0.90.90.50.00.3-0.3-0.50.40.40.20.00.0-0.00.10.4
Short access total infusions0.10.20.50.4-0.40.6-0.30.10.5-0.6-0.60.70.2-0.30.2-0.0-0.70.60.60.1-0.1-0.00.00.00.2
Short access day 1 locomotion0.10.21.2-0.50.4-0.10.00.10.1-0.1-0.10.2-0.5-0.80.00.2-1.10.50.50.1-0.4-0.10.1-0.3-0.2
Short access day 10 total locomotion0.30.62.21.1-0.90.7-1.2-1.50.2-0.3-0.30.31.10.8-0.2-1.20.1-0.6-0.6-0.40.70.8-0.80.71.0
Short access total locomotion0.40.41.8-0.1-0.00.20.60.50.5-0.5-0.50.6-0.7-0.90.60.5-1.31.01.00.6-0.8-0.70.7-0.7-0.0
One hour access (0.3 mA shock)0.80.91.70.6-0.30.1-1.3-1.3-0.40.40.4-0.41.31.0-0.9-1.20.8-1.1-1.1-1.01.11.2-1.21.31.1
Compulsive drug intake0.30.40.9-0.70.8-0.90.3-0.1-0.91.01.0-1.0-0.10.2-0.6-0.10.7-0.6-0.6-0.50.30.3-0.30.40.6
One hour access (shock baseline)0.40.72.00.5-0.30.1-1.4-1.3-0.30.20.2-0.21.10.7-0.7-1.20.4-0.7-0.7-0.81.01.0-1.01.01.0
Social response proportion0.30.40.80.7-0.80.70.30.10.6-0.9-0.90.9-0.0-0.10.80.4-0.40.40.40.8-0.3-0.70.6-0.60.2
Social responses0.40.51.50.4-0.2-0.0-0.7-0.9-0.40.20.2-0.20.90.9-0.6-0.90.9-0.8-0.8-0.70.90.8-0.80.81.2
Social time0.30.51.71.3-1.20.9-0.5-0.90.7-0.7-0.70.61.00.80.2-0.70.4-0.3-0.20.00.40.4-0.50.40.6
Soleus weight0.00.00.30.2-0.30.00.50.20.10.20.2-0.2-0.00.20.30.2-0.1-0.2-0.20.3-0.2-0.20.2-0.2-0.3
Bone: stiffness0.81.44.9-2.22.1-1.81.51.6-1.21.21.2-1.2-1.5-1.2-0.61.0-0.60.40.3-0.3-0.5-0.50.5-0.50.0
Tibialis anterior weight0.20.62.41.6-1.41.0-0.4-1.00.5-0.4-0.40.41.31.30.2-0.70.6-0.8-0.9-0.00.50.5-0.50.50.2
Time to tail flick, vehicle, before self-admin1.41.42.60.4-0.70.8-0.90.61.2-0.9-0.90.9-0.9-1.31.51.2-1.61.21.21.6-1.3-1.61.6-1.6-1.1
Time to tail flick, vehicle, after self-admin0.60.83.1-0.60.8-0.8-0.9-1.1-0.90.90.9-0.90.20.4-0.9-1.20.6-0.7-0.7-0.80.70.8-0.80.71.8
Time to tail flick, test, before self-admin1.92.04.1-0.0-0.30.51.71.71.1-1.0-1.01.0-1.2-1.71.41.9-2.01.41.41.5-1.5-1.61.6-1.6-2.0
Time to tail flick, test, after self-admin0.80.81.30.4-0.60.60.30.61.0-1.1-1.11.1-0.5-0.51.10.9-0.81.01.01.1-1.0-1.11.1-0.9-0.9
Delta time to tail flick, vehicle, before/after SA2.72.64.4-1.21.6-1.6-0.0-1.0-1.91.71.7-1.70.71.1-2.1-1.61.4-1.6-1.6-2.01.72.0-2.01.82.1
Delta time to tail flick, test, before/after SA0.20.20.70.5-0.40.3-0.7-0.80.2-0.2-0.20.20.50.8-0.0-0.70.7-0.2-0.2-0.10.30.3-0.30.40.6
Tibia length0.92.44.20.9-1.31.50.40.92.0-1.9-1.91.9-0.7-1.21.91.3-1.61.71.71.8-1.7-1.51.5-1.5-1.9
Ambulatory time before self-admin0.30.51.5-1.21.2-1.01.20.7-1.00.80.8-0.8-0.4-0.2-0.80.20.2-0.2-0.2-0.60.40.4-0.40.40.5
Ambulatory time after self-admin0.60.81.3-0.2-0.10.31.20.80.7-0.7-0.70.7-1.0-1.00.90.8-1.11.01.01.0-1.1-1.01.0-1.1-0.5
Bone: tissue strength0.90.92.91.7-1.61.3-1.2-1.30.8-0.9-0.90.91.41.10.3-0.90.7-0.5-0.60.00.50.5-0.50.60.2
Total heroin consumption0.20.20.80.9-0.80.50.3-0.20.4-0.3-0.30.20.80.7-0.0-0.20.1-0.5-0.5-0.10.30.2-0.20.5-0.2
Bone: trabecular number0.30.41.5-0.91.0-1.11.20.5-0.90.90.9-0.9-0.30.1-0.70.10.1-0.3-0.3-0.60.30.2-0.20.30.3
Bone: trabecular spacing0.81.12.61.4-1.61.5-0.3-0.11.5-1.5-1.51.50.1-0.21.40.4-0.70.90.91.2-0.8-0.80.8-0.8-0.9
Bone: trabecular thickness0.30.40.7-0.30.4-0.5-0.2-0.4-0.60.70.7-0.70.40.6-0.8-0.60.6-0.8-0.8-0.80.70.7-0.70.70.5
Bone: trabecular tissue density1.92.85.9-1.61.2-0.71.82.40.2-0.1-0.10.1-2.4-2.41.02.2-2.02.11.91.3-1.9-2.02.0-1.9-1.1
Water consumed over 24 hours0.91.22.2-0.71.0-1.1-0.7-0.4-1.31.51.5-1.40.60.7-1.5-0.71.2-1.2-1.3-1.41.01.3-1.31.30.2
Number of responses in last shaping day0.10.10.60.2-0.30.20.5-0.10.1-0.2-0.20.20.0-0.20.20.0-0.8-0.0-0.00.2-0.1-0.30.3-0.10.7