Hub : Genes

Lig1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Lig1 0.17 0.12 3.2e-03 0.07 0.09 0.09 0.07 1.1e-02 4.0e-03 3.4e-03 9.1e-03
2 NAcc mRNA stability Lig1 0.08 0.05 1.1e-08 0.04 0.07 0.06 0.06 2.3e-05 3.7e-08 3.8e-07 1.2e-07
3 OFC mRNA stability Lig1 0.23 0.15 1.4e-03 0.01 0.04 0.03 0.02 1.5e-01 3.9e-02 8.3e-02 9.5e-02
4 Adipose mRNA stability Lig1 0.04 0.03 1.8e-03 0.01 0.02 0.02 0.02 3.6e-02 3.0e-03 6.3e-03 5.8e-03
5 NAcc intron excision ratio chr1_74203426_74203983 0.03 0.02 2.0e-03 0.01 0.01 -0 0 5.7e-02 3.0e-02 9.7e-01 2.4e-01
6 pVTA mRNA stability Lig1 0.11 0.08 4.9e-04 0.01 0.04 0.03 0.01 8.8e-02 9.1e-03 1.6e-02 1.2e-01
7 Liver mRNA stability Lig1 0.03 0.02 5.0e-03 0.01 0.01 0.01 0.01 6.6e-02 9.5e-03 5.3e-02 3.2e-02
8 LHb mRNA stability Lig1 0.38 0.18 3.3e-06 0.07 0.11 0.11 0.11 1.0e-02 1.6e-03 1.6e-03 1.4e-03
9 pVTA gene expression Lig1 0.2 0.12 5.9e-06 0.12 0.11 0.12 0.11 9.9e-06 1.7e-05 7.7e-06 2.0e-05
10 NAcc intron excision ratio chr1_74202463_74203983 0.06 0.04 3.9e-06 0.03 0.04 0.04 0.03 6.1e-04 2.0e-05 4.3e-05 7.4e-05
11 Brain mRNA stability Lig1 0.17 0.09 1.8e-15 0.15 0.16 0.16 0.16 8.6e-14 1.5e-14 3.4e-15 7.7e-15
12 Brain intron excision ratio chr1_74202463_74203983 0.18 0.11 1.2e-14 0.17 0.15 0.17 0.17 2.3e-15 3.5e-14 3.1e-15 1.3e-15
13 BLA gene expression Lig1 0.29 0.13 4.2e-12 0.14 0.16 0.14 0.15 6.8e-08 7.0e-09 3.5e-08 3.0e-08
14 BLA mRNA stability Lig1 0.12 0.07 4.6e-05 0.05 0.04 0.03 0.04 9.6e-04 2.1e-03 1.2e-02 2.6e-03
15 OFC gene expression Lig1 0.16 0.12 6.4e-03 0.1 0.1 0.1 0.1 2.0e-03 2.2e-03 2.8e-03 2.5e-03
16 Brain intron excision ratio chr1_74203426_74203983 0.09 0.06 1.4e-07 0.1 0.07 0.09 0.09 2.2e-09 4.0e-07 1.7e-08 5.1e-09
17 NAcc gene expression Lig1 0.04 0.03 3.8e-04 0.03 0.02 0.01 0.02 4.5e-04 1.0e-03 2.8e-02 1.4e-03
18 PL intron excision ratio chr1_74203426_74203983 0.05 0.04 1.9e-05 0.04 0.03 0.03 0.03 6.5e-05 1.8e-04 3.6e-04 1.2e-04
19 PL mRNA stability Lig1 0.1 0.06 2.5e-09 0.08 0.07 0.07 0.07 3.3e-09 1.2e-08 1.8e-08 2.5e-08
20 PL intron excision ratio chr1_74202463_74203983 0.07 0.05 1.9e-07 0.05 0.05 0.04 0.04 4.4e-06 6.5e-06 1.3e-05 1.3e-05
21 Eye gene expression Lig1 0.36 0.21 3.9e-03 0.1 0.1 0.14 0.11 1.1e-02 1.3e-02 3.6e-03 1.0e-02
22 PL gene expression Lig1 0.17 0.09 0.0e+00 0.15 0.16 0.15 0.16 2.8e-16 7.3e-17 7.9e-16 3.5e-17
23 Adipose gene expression Lig1 0.12 0.07 5.4e-11 0.09 0.09 0.09 0.09 2.3e-10 2.4e-10 5.9e-10 8.0e-10
24 Brain gene expression Lig1 0.15 0.09 1.4e-11 0.14 0.12 0.12 0.12 1.2e-12 1.4e-11 2.2e-11 1.1e-11
25 IL mRNA stability Lig1 0.41 0.19 1.7e-07 0.37 0.34 0.37 0.36 7.5e-10 7.3e-09 1.1e-09 1.6e-09
26 Liver gene expression Lig1 0.1 0.06 1.5e-09 0.06 0.07 0.07 0.07 2.2e-07 3.2e-08 7.4e-08 5.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.20.31.10.50.20.20.3-0.40.50.50.40.50.50.3-0.5-0.30.20.6-0.60.4-0.20.40.40.7-0.50.80.7-0.6-1.0
Area under the delay curve1.31.42.21.3-1.4-1.4-1.41.4-1.3-1.4-1.31.4-1.31.1-1.0-1.21.21.0-1.01.2-1.31.11.10.7-1.00.70.81.50.0
BMI with tail0.41.45.5-1.3-0.5-0.6-0.81.0-1.1-1.1-1.1-1.1-1.3-0.50.90.7-0.9-0.90.9-0.91.0-0.9-0.9-1.51.2-2.0-1.81.82.4
BMI without tail1.12.36.5-1.8-0.0-0.1-0.40.6-0.7-0.7-0.6-1.9-0.9-1.01.61.2-1.5-1.61.6-1.41.5-1.4-1.4-2.31.6-2.6-2.41.92.5
Body weight1.14.89.0-3.01.51.41.2-1.00.80.80.8-2.80.6-2.32.62.4-2.6-2.62.6-2.52.6-2.4-2.5-2.82.6-2.9-2.6-0.12.2
Weight adjusted by age1.71.92.7-1.41.61.61.6-1.51.51.61.6-1.61.5-1.61.51.4-1.6-1.41.4-1.51.2-1.3-1.5-1.21.0-1.1-0.6-0.80.0
Bone surface1.73.06.9-1.22.42.42.5-2.62.62.62.5-1.02.6-1.61.01.5-1.5-1.01.0-1.31.2-1.3-1.3-0.51.00.10.1-2.6-1.3
Bone volume1.11.95.9-0.71.91.92.0-2.12.12.12.1-0.62.2-1.10.61.0-0.9-0.60.6-0.80.9-0.9-0.8-0.10.60.40.2-2.4-1.4
Breakpoint value in progressive ratio session6.47.010.72.9-3.3-3.3-3.23.2-3.1-3.1-3.12.6-3.12.9-2.5-2.82.72.5-2.52.5-2.72.72.41.9-2.31.51.22.50.2
Number of licking bursts1.41.62.9-1.60.80.70.6-0.40.40.40.4-1.70.2-1.41.61.4-1.5-1.61.6-1.51.2-1.4-1.5-1.71.6-1.7-1.70.21.5
Context. condit. distance diff. score0.10.10.3-0.20.40.40.4-0.30.30.30.3-0.40.3-0.40.30.4-0.5-0.30.3-0.40.3-0.5-0.4-0.40.4-0.3-0.10.10.2
Locomotion velocity, session 10.30.41.20.70.30.30.4-0.50.60.50.50.60.60.3-0.7-0.30.10.7-0.70.4-0.40.30.40.7-0.51.01.1-0.5-1.1
Locomotion distance, session 11.21.54.1-0.31.71.81.8-1.92.02.02.0-0.62.0-1.10.80.9-0.4-0.70.7-0.70.8-0.7-0.7-0.40.50.40.4-1.4-1.3
Locomotion velocity, session 21.01.21.7-1.11.21.21.1-1.11.11.11.0-1.11.0-1.21.11.3-0.8-1.01.0-1.31.3-1.3-1.3-1.11.3-0.9-0.7-0.40.4
Locomotion distance, session 22.53.45.0-1.82.22.22.2-2.22.12.22.2-1.82.1-2.02.01.9-1.3-2.02.0-1.82.0-1.8-1.8-1.61.6-1.0-1.2-1.6-0.1
Locomotion velocity, session 30.10.20.3-0.50.40.40.4-0.30.30.30.4-0.40.3-0.50.60.4-0.2-0.60.6-0.40.4-0.5-0.4-0.40.4-0.3-0.5-0.30.2
Locomotion distance, session 30.70.72.1-0.11.21.21.3-1.41.41.41.4-0.31.5-0.70.40.50.2-0.40.4-0.30.5-0.4-0.3-0.10.10.50.2-1.3-1.1
Stereotopy head waving bouts, day 30.30.41.40.1-0.7-0.7-0.80.9-0.9-0.9-1.00.2-1.00.4-0.2-0.20.10.2-0.20.1-0.40.10.1-0.10.1-0.4-0.31.20.9
Stereotopy head waving duration, day 30.40.51.30.4-1.0-1.0-1.01.1-1.1-1.1-1.10.5-1.10.7-0.6-0.50.30.6-0.60.4-0.70.40.40.3-0.2-0.00.01.00.7
Locomotion velocity, session 70.80.92.71.0-0.3-0.3-0.10.00.00.0-0.11.20.10.9-1.2-0.91.31.2-1.21.0-1.10.91.01.4-1.01.31.6-0.7-1.3
Locomotion distance, session 70.10.10.60.30.00.10.1-0.10.20.20.10.30.20.2-0.3-0.20.80.3-0.30.2-0.30.10.20.3-0.20.40.4-0.2-0.4
Stereotopy head waving bouts, day 70.30.40.7-0.70.70.80.8-0.70.70.70.6-0.40.7-0.60.40.7-0.6-0.40.4-0.70.5-0.7-0.7-0.20.6-0.30.1-0.90.0
Stereotopy head waving duration, day 70.30.40.6-0.80.60.70.7-0.60.60.60.5-0.50.5-0.70.60.7-0.8-0.60.6-0.70.6-0.7-0.7-0.50.7-0.5-0.3-0.70.3
Locomotion velocity, session 80.00.00.20.10.30.20.3-0.30.30.30.4-0.00.4-0.20.10.00.1-0.10.10.00.1-0.10.0-0.0-0.10.10.30.0-0.4
Locomotion distance, session 80.71.01.7-0.81.31.31.3-1.31.31.31.3-0.91.2-1.11.01.1-0.6-1.01.0-1.01.1-1.0-1.0-0.90.9-0.5-0.5-0.7-0.1
Degree of sensitization distance0.30.30.80.3-0.8-0.8-0.80.8-0.8-0.8-0.90.4-0.90.6-0.5-0.40.30.5-0.50.4-0.60.30.40.3-0.2-0.00.10.80.5
Degree of sensitization stereotypy1.31.52.0-1.31.41.41.4-1.31.31.31.2-1.11.2-1.31.11.4-1.3-1.21.2-1.41.3-1.4-1.4-1.01.3-0.9-0.6-1.00.3
Conditioned locomotion0.10.10.5-0.10.20.20.1-0.10.10.10.2-0.50.1-0.40.50.3-0.4-0.50.5-0.30.3-0.3-0.3-0.60.3-0.4-0.40.70.2
Cocaine response after cond. corrected0.60.72.0-0.0-1.2-1.2-1.21.3-1.4-1.4-1.40.5-1.40.8-0.6-0.50.70.6-0.60.5-0.60.50.50.4-0.3-0.3-0.10.30.9
Cocaine response after cond. not corrected0.30.41.1-1.00.40.40.4-0.30.20.30.2-0.70.2-0.60.70.7-0.6-0.70.7-0.70.6-0.7-0.7-0.50.7-0.7-0.6-0.80.6
Cocaine response before conditioning6.78.212.6-2.43.53.53.5-3.53.53.53.5-2.63.4-3.12.82.9-3.1-2.82.8-2.82.7-2.8-2.8-2.32.4-1.3-1.5-2.4-0.3
Saline control response1.92.43.3-1.31.81.81.7-1.71.71.71.8-1.71.7-1.81.81.6-1.6-1.81.8-1.51.5-1.5-1.5-1.61.4-0.9-1.1-0.70.0
Bone: connectivity density0.10.10.50.40.30.30.3-0.40.40.40.40.30.50.1-0.4-0.1-0.10.4-0.40.1-0.00.10.10.4-0.20.50.5-0.2-0.7
Bone: cortical apparent density0.40.51.10.3-1.0-1.0-1.01.0-1.0-1.0-1.00.5-1.00.7-0.5-0.61.00.5-0.50.6-0.50.60.60.4-0.40.1-0.00.30.4
Bone: cortical area0.91.41.9-1.01.41.41.3-1.31.31.31.3-1.31.2-1.31.31.3-1.3-1.31.3-1.21.0-1.3-1.2-1.11.2-0.8-1.0-0.70.1
Bone: cortical porosity0.40.40.90.2-0.9-0.9-0.90.9-0.9-1.0-1.00.4-1.00.6-0.6-0.50.30.6-0.60.4-0.40.50.40.4-0.3-0.1-0.00.50.5
Bone: cortical porosity0.10.10.6-0.4-0.3-0.3-0.40.5-0.5-0.5-0.5-0.2-0.50.00.10.1-0.2-0.10.1-0.20.2-0.1-0.2-0.20.3-0.6-0.50.20.8
Bone: cortical thickness0.30.51.20.5-0.9-0.9-1.01.0-1.0-1.0-0.90.4-1.00.6-0.4-0.60.50.3-0.30.5-0.70.50.50.1-0.4-0.0-0.41.10.5
Bone: cortical thickness0.30.30.6-0.60.60.60.6-0.50.50.50.5-0.50.5-0.60.60.6-0.8-0.60.6-0.60.5-0.6-0.6-0.50.5-0.4-0.5-0.60.1
Bone: cortical tissue density0.40.51.10.3-1.0-1.0-1.01.0-1.0-1.0-1.00.5-1.00.7-0.5-0.71.00.5-0.50.6-0.50.60.60.5-0.50.20.00.20.4
Condit. Reinf. active minus inactive responses0.40.51.6-0.9-0.0-0.1-0.20.3-0.3-0.3-0.2-0.8-0.4-0.60.80.5-0.6-0.80.8-0.60.6-0.5-0.6-0.90.7-1.2-1.30.51.1
Condit. Reinf. active-inactive response ratio0.60.62.3-0.7-0.5-0.5-0.60.8-0.8-0.8-0.7-0.7-0.9-0.30.70.3-0.6-0.70.7-0.50.4-0.4-0.5-1.00.6-1.3-1.41.21.5
Condit. Reinf. active responses0.40.51.0-1.00.50.50.5-0.40.40.40.5-0.80.3-0.90.90.7-0.7-0.90.9-0.70.8-0.7-0.7-0.80.6-0.9-1.0-0.40.4
Condit. Reinf. inactive responses0.70.93.3-0.31.21.21.3-1.41.41.41.5-0.31.5-0.70.40.4-0.3-0.40.4-0.20.4-0.3-0.20.1-0.00.50.5-1.8-1.3
Incentive salience index mean0.60.71.3-1.00.60.60.5-0.40.40.40.4-1.00.3-1.01.10.8-0.9-1.11.1-0.91.0-0.9-0.9-1.10.8-1.1-1.10.00.7
Condit. Reinf. lever presses0.50.71.3-0.70.90.90.8-0.80.80.80.9-0.90.8-1.01.00.8-0.7-1.01.0-0.81.1-0.8-0.8-0.90.7-0.6-0.7-0.30.1
Condit. Reinf. active minus inactive responses2.02.56.1-0.92.22.22.3-2.42.42.42.4-0.92.5-1.41.11.2-1.0-1.11.1-1.00.9-1.1-1.0-0.50.70.30.2-2.3-1.4
Condit. Reinf. active-inactive response ratio2.02.15.8-1.01.92.02.1-2.12.12.12.1-0.92.2-1.31.01.2-1.1-1.01.0-1.00.8-1.0-1.0-0.40.70.10.2-2.4-1.1
Condit. Reinf. active responses1.92.66.6-0.72.22.22.3-2.52.52.52.5-1.02.6-1.41.11.2-0.7-1.11.1-1.00.9-1.1-1.0-0.50.70.40.2-2.1-1.5
Condit. Reinf. inactive responses0.10.10.40.40.30.30.4-0.50.50.50.50.10.5-0.0-0.0-0.00.40.0-0.00.10.00.00.10.1-0.20.50.20.0-0.6
Condit. Reinf. lever presses0.81.11.9-1.01.11.11.0-1.00.91.01.0-1.30.9-1.21.41.1-0.9-1.31.3-1.11.1-1.2-1.1-1.31.1-0.9-0.9-0.20.4
Condit. Reinf. lever reinforcers received2.53.58.5-1.02.62.62.7-2.82.92.92.9-1.22.9-1.71.41.5-0.9-1.41.4-1.31.2-1.4-1.3-0.80.90.30.0-2.4-1.5
Conditioned reinforcement - actives0.70.72.9-1.7-0.2-0.2-0.30.5-0.6-0.5-0.4-0.7-0.6-0.40.90.7-0.7-1.01.0-0.70.4-0.6-0.8-1.01.0-1.5-1.30.01.6
Conditioned reinforcement - inactives2.62.95.2-2.31.91.91.9-1.81.81.81.8-2.01.7-1.82.01.8-1.6-1.91.9-1.61.6-1.7-1.6-1.61.7-1.0-1.2-1.40.2
Conditioned locomotion0.30.41.9-1.0-0.3-0.2-0.30.5-0.5-0.5-0.5-0.4-0.6-0.20.50.5-0.3-0.50.5-0.70.2-0.5-0.8-0.50.9-0.9-0.80.11.4
Patch foraging indifference point 0 sec0.10.22.00.4-0.6-0.6-0.70.6-0.6-0.6-0.5-0.0-0.60.4-0.1-0.4-0.10.1-0.10.3-0.20.40.3-0.2-0.3-0.0-0.11.40.3
Patch foraging indifference point AUC1.82.04.8-1.50.80.70.5-0.30.30.30.3-1.50.1-1.51.71.6-1.4-1.71.7-1.71.8-1.6-1.7-1.91.8-2.2-2.00.61.9
Delay disc. indifference point, 0s delay0.30.41.21.00.70.70.7-0.91.00.90.90.51.0-0.2-0.20.0-0.00.2-0.20.1-0.2-0.0-0.00.2-0.10.80.40.1-1.1
Delay disc. indifference point, 16s delay2.02.13.71.2-1.9-1.9-1.81.9-1.9-1.9-1.91.6-1.91.4-1.4-1.41.41.3-1.31.3-1.41.21.11.1-1.10.50.30.80.5
Delay disc. indifference point, 2s delay0.70.81.81.0-0.9-0.9-0.90.8-0.8-0.8-0.81.4-0.80.8-1.0-0.90.91.0-1.00.9-1.00.80.80.8-0.90.70.90.7-0.3
Delay disc. indifference point, 24s delay0.70.71.80.5-1.2-1.2-1.21.3-1.3-1.3-1.30.7-1.30.4-0.4-0.60.50.4-0.40.8-0.60.30.70.2-0.2-0.2-0.11.10.8
Delay disc. indifference point, 4s delay0.10.10.4-0.60.50.50.5-0.40.40.40.4-0.30.4-0.40.40.5-0.4-0.40.4-0.50.1-0.4-0.4-0.30.4-0.30.0-0.30.1
Delay disc. indifference point, 8s delay1.31.42.01.2-1.4-1.4-1.41.3-1.3-1.3-1.11.0-1.21.2-0.7-1.41.30.7-0.71.4-1.41.31.30.6-1.21.00.81.4-0.3
Indifference point function ln k1.42.08.80.91.11.21.4-1.71.81.81.80.72.00.2-0.6-0.50.30.7-0.70.8-0.70.70.81.3-1.12.32.0-2.1-3.0
Indifference point function log k1.42.08.80.91.11.21.4-1.71.81.81.80.72.00.2-0.6-0.50.30.7-0.70.8-0.70.70.81.3-1.12.32.0-2.1-3.0
Patch foraging total patch changes 0 sec0.20.32.30.3-0.6-0.7-0.70.7-0.7-0.7-0.6-0.1-0.70.40.0-0.4-0.10.0-0.00.3-0.20.30.3-0.3-0.2-0.1-0.31.50.4
Patch foraging total patch changes 12 sec0.60.82.2-0.80.10.1-0.10.2-0.3-0.3-0.2-1.0-0.4-0.81.10.8-0.9-1.11.1-1.01.0-0.9-1.0-1.31.0-1.5-1.41.11.5
Patch foraging total patch changes 18 sec1.11.43.6-1.10.40.30.10.0-0.1-0.10.1-1.5-0.2-1.21.71.0-1.5-1.71.7-1.21.2-1.1-1.2-1.91.2-1.7-1.71.21.6
Patch foraging total patch changes 24 sec1.01.22.5-1.50.60.60.4-0.30.20.20.2-1.20.1-1.11.21.2-1.3-1.21.2-1.31.3-1.2-1.3-1.31.3-1.6-1.5-0.11.4
Patch foraging total patch changes 6 sec0.50.72.8-0.6-0.6-0.6-0.80.9-1.0-1.0-0.9-0.7-1.1-0.20.60.3-0.4-0.60.6-0.50.2-0.4-0.5-0.90.6-1.4-1.31.41.7
Patch foraging time to switch 0 sec5.38.113.01.8-3.6-3.6-3.53.5-3.5-3.5-3.62.6-3.43.3-2.9-2.92.72.9-2.92.8-3.02.82.82.6-2.41.41.51.50.4
Patch foraging water rate 0 sec2.74.35.8-1.72.42.42.3-2.22.22.22.2-2.12.1-2.42.12.3-2.4-2.12.1-2.22.2-2.2-2.2-2.12.0-1.6-1.6-0.80.4
Patch foraging water rate 12 sec1.01.53.80.11.71.71.7-1.91.91.91.9-0.61.9-1.20.90.9-0.8-0.90.9-0.80.9-0.8-0.8-0.70.50.3-0.4-0.7-1.1
Patch foraging water rate 18 sec0.10.20.50.40.60.60.6-0.70.70.70.7-0.00.7-0.30.10.2-0.2-0.10.1-0.1-0.2-0.2-0.10.00.10.3-0.0-0.3-0.6
Patch foraging water rate 24 sec0.40.51.60.01.01.01.0-1.21.21.21.3-0.41.3-0.40.50.2-0.4-0.40.4-0.10.2-0.2-0.1-0.2-0.00.60.2-0.9-1.1
Patch foraging water rate 6 sec6.49.414.4-2.83.83.83.8-3.73.73.73.6-2.73.6-3.32.93.2-3.1-2.82.8-3.03.1-3.0-3.0-2.42.7-1.6-1.8-2.7-0.3
Seeking ratio, delayed vs. immediate footshock0.60.62.31.30.00.00.1-0.30.40.40.40.60.50.7-0.7-0.80.60.8-0.80.9-0.80.80.90.7-1.11.51.10.5-1.5
Distance traveled before self-admin1.11.23.3-0.21.51.51.5-1.71.71.71.8-0.41.7-0.91.00.8-0.4-1.01.0-0.80.6-0.9-0.8-0.70.60.4-0.0-0.8-1.0
Distance traveled after self-admin0.60.72.61.50.70.70.8-1.01.11.11.20.71.1-0.1-0.2-0.30.80.2-0.20.3-0.20.20.30.2-0.51.31.10.0-1.6
Extensor digitorum longus weight1.35.38.3-2.62.01.91.7-1.61.51.51.6-2.81.3-2.62.92.5-2.6-2.82.8-2.62.7-2.5-2.6-2.92.6-2.4-2.5-0.41.6
Bone: elastic displacement2.93.34.72.2-1.8-1.8-1.71.6-1.5-1.5-1.52.1-1.42.0-2.2-2.11.52.1-2.12.1-2.02.12.12.0-2.01.61.71.0-0.9
Bone: elastic work0.10.20.50.60.10.10.1-0.20.20.20.10.60.20.3-0.6-0.3-0.20.6-0.60.3-0.20.30.30.5-0.40.50.7-0.1-0.7
Bone: endosteal estimation1.94.19.4-1.32.72.72.8-2.92.92.92.9-1.42.9-1.91.61.7-1.7-1.51.5-1.51.5-1.6-1.5-0.81.10.10.0-3.1-1.3
Bone: endosteal perimeter1.22.45.2-1.02.12.12.2-2.32.32.32.2-1.12.3-1.51.11.4-1.5-1.01.0-1.21.1-1.3-1.2-0.61.0-0.1-0.0-2.0-1.0
Epididymis fat weight1.43.34.81.3-2.2-2.2-2.12.1-2.1-2.1-2.11.7-2.02.1-1.9-2.01.61.9-1.91.9-1.81.91.91.7-1.71.01.11.2-0.1
Delta time in closed arm before/after self-admin0.10.10.4-0.40.30.30.3-0.30.30.30.2-0.70.2-0.30.40.3-0.5-0.40.4-0.40.5-0.4-0.3-0.40.4-0.4-0.20.10.1
Delta time in open arm before/after self-admin0.30.30.5-0.60.70.70.7-0.70.70.70.6-0.40.7-0.50.30.6-0.6-0.30.3-0.40.4-0.5-0.5-0.40.5-0.4-0.3-0.3-0.1
Diff in mean of infusions in LGA sessions1.11.22.71.6-1.0-1.0-0.90.8-0.8-0.8-0.61.3-0.71.2-1.3-1.21.51.3-1.31.2-1.41.21.21.1-1.11.01.10.9-0.6
Delay discount exponential model param1.11.12.2-1.11.31.31.3-1.31.31.31.2-1.21.3-0.90.81.1-1.1-0.70.7-1.11.2-0.9-1.0-0.50.9-0.5-0.7-1.5-0.1
Extinction: sum of active levers before priming0.30.31.41.2-0.2-0.2-0.20.10.00.00.10.60.00.5-0.7-0.60.70.7-0.70.4-0.50.70.30.5-0.60.80.70.6-0.7
Active lever presses in extinction session 60.70.62.6-1.2-0.2-0.2-0.30.6-0.6-0.6-0.7-0.9-0.7-0.10.40.6-0.5-0.40.4-0.90.7-0.7-0.8-0.71.1-1.3-1.60.21.6
Bone: final force2.03.24.4-1.62.12.12.1-2.12.02.02.1-1.82.0-1.91.91.8-2.1-1.81.8-1.71.5-1.8-1.7-1.51.6-0.8-1.0-1.8-0.1
Bone: final moment2.54.15.9-1.82.42.42.4-2.42.42.42.4-2.02.3-2.22.12.0-2.3-2.02.0-1.91.7-2.0-1.9-1.61.7-0.9-1.0-2.0-0.2
Food consumed during 24 hour testing period1.41.63.51.6-0.7-0.7-0.50.3-0.3-0.2-0.21.5-0.11.2-1.3-1.51.81.3-1.31.6-1.71.51.61.6-1.61.91.6-0.5-1.6
Glucose1.82.74.22.0-1.6-1.6-1.51.4-1.4-1.4-1.41.9-1.31.9-2.0-1.91.32.0-2.01.8-1.91.81.81.7-1.71.51.51.2-0.8
Heart weight0.71.11.6-0.81.21.21.1-1.11.11.11.1-1.21.0-1.21.11.1-1.2-1.11.1-1.01.1-1.0-1.0-1.10.9-0.7-1.0-0.30.1
Delay discount hyperbolic model param0.60.71.4-0.81.01.01.0-1.01.01.00.9-0.91.0-0.70.60.8-0.8-0.50.5-0.81.0-0.7-0.8-0.30.7-0.4-0.5-1.2-0.1
Intermittent access intake day 1-15 change0.20.20.6-0.70.40.40.4-0.40.30.30.4-0.50.3-0.60.70.5-0.4-0.70.7-0.40.6-0.4-0.4-0.70.4-0.6-0.1-0.30.2
Intermittent access intake escalation0.10.10.4-0.60.10.10.1-0.0-0.0-0.00.1-0.4-0.0-0.30.60.2-0.2-0.60.6-0.10.3-0.2-0.2-0.50.1-0.5-0.0-0.20.3
Intermittent access intake escalation 20.30.31.0-0.70.60.50.5-0.50.50.50.6-0.60.5-0.61.00.5-0.6-1.01.0-0.50.4-0.4-0.6-0.80.3-0.3-0.0-0.40.0
Intermitt. access day 1 inactive lever presses0.30.31.1-0.90.40.50.5-0.30.30.3-0.0-0.20.2-0.3-0.10.9-0.50.1-0.1-0.70.9-0.8-0.70.10.8-0.5-0.9-1.00.7
Intermitt. access day 15 inactive lever presses2.52.86.9-2.61.51.51.5-1.31.11.11.1-2.01.0-1.61.62.0-1.9-1.61.6-1.62.0-2.0-1.7-1.42.2-1.9-1.7-1.51.2
Intermitt. access escalation Index0.80.72.20.4-1.1-1.1-1.21.2-1.3-1.3-1.20.2-1.30.6-0.3-0.60.50.3-0.30.5-0.40.40.50.0-0.4-0.3-0.51.50.8
Intermittent access day 1 total infusions0.70.82.3-1.50.80.80.8-0.70.60.70.6-1.40.6-0.50.81.0-0.9-0.70.7-1.00.8-1.0-0.9-0.71.0-0.7-1.2-0.60.6
Intermittent access day 15 total infusions0.20.21.6-1.2-0.2-0.2-0.20.3-0.4-0.3-0.3-0.7-0.40.10.40.3-0.3-0.30.3-0.20.2-0.2-0.2-0.30.3-0.7-0.7-0.20.8
Intermittent access terminal intake (last 3 days)0.10.21.4-1.20.20.20.2-0.10.00.10.1-0.60.1-0.10.30.4-0.4-0.30.3-0.40.3-0.3-0.4-0.20.4-0.5-0.5-0.60.4
Intermittent access total infusions0.40.42.6-1.60.40.50.5-0.40.30.30.2-1.00.3-0.30.50.8-0.8-0.40.4-0.70.6-0.7-0.7-0.40.8-0.8-0.9-0.70.6
Intermittent access day 1 locomotion0.20.20.70.2-0.2-0.2-0.10.0-0.0-0.0-0.10.40.00.5-0.5-0.40.50.5-0.50.5-0.70.40.50.7-0.40.80.7-0.6-0.5
Intermittent access day 15 total locomotion0.40.40.70.4-0.8-0.7-0.70.7-0.7-0.7-0.70.5-0.70.8-0.5-0.60.70.5-0.50.7-0.90.60.70.5-0.40.60.70.20.0
Intermittent access total locomotion0.10.10.5-0.20.20.20.3-0.20.20.30.20.00.30.2-0.10.10.10.2-0.2-0.1-0.1-0.1-0.10.30.20.50.4-0.7-0.1
Intermittent access standard deviation0.60.73.3-1.0-0.5-0.5-0.60.8-0.9-0.8-0.9-0.6-1.0-0.00.50.5-0.2-0.50.5-0.70.7-0.5-0.8-0.70.8-1.4-1.30.51.8
Left kidney weight8.724.331.3-5.65.15.04.7-4.44.34.34.3-5.44.0-5.65.55.6-5.6-5.45.4-5.55.6-5.4-5.5-5.15.3-4.4-4.5-2.62.2
Right kidney weight4.813.418.7-4.33.63.63.3-3.02.92.92.9-4.12.7-4.14.04.2-4.2-3.93.9-4.24.2-4.1-4.2-3.84.1-3.5-3.5-1.92.0
Cocaine induced anxiety0.80.94.30.60.80.81.0-1.21.31.31.40.21.5-0.20.1-0.30.1-0.00.00.4-0.30.50.30.5-0.91.61.4-1.4-2.1
Post-drug Anxiety0.10.11.5-0.50.30.30.4-0.40.30.40.4-0.40.4-0.10.2-0.1-0.1-0.10.10.10.20.20.10.2-0.30.20.2-1.2-0.5
Baseline Anxiety0.50.51.4-0.4-1.0-1.0-1.01.1-1.2-1.2-1.10.0-1.20.6-0.3-0.30.40.3-0.30.4-0.30.20.40.2-0.0-0.7-0.30.21.0
Tail length0.82.54.1-1.71.61.51.4-1.41.31.31.4-2.01.3-1.82.01.6-1.8-1.91.9-1.61.5-1.6-1.6-1.91.5-1.4-1.6-0.20.5
Length with tail1.45.27.1-2.42.72.72.6-2.62.52.52.5-2.42.5-2.52.52.4-2.2-2.42.4-2.32.2-2.2-2.3-1.92.1-1.3-1.5-2.10.1
Length without tail0.92.03.5-1.51.71.71.8-1.71.71.71.6-1.31.6-1.41.31.5-1.3-1.21.2-1.41.4-1.3-1.4-0.81.2-0.6-0.4-1.9-0.1
Times rat made contact with spout0.30.40.80.9-0.5-0.5-0.40.4-0.3-0.3-0.30.7-0.30.6-0.7-0.70.80.7-0.70.7-0.70.70.70.6-0.70.70.50.7-0.5
Lifetime Intake0.30.42.4-1.60.30.30.3-0.20.10.10.1-1.10.1-0.20.50.6-0.7-0.30.3-0.60.6-0.6-0.6-0.50.6-0.8-0.9-0.40.6
Liver weight, left7.812.522.5-4.72.22.21.8-1.31.11.21.2-4.40.8-3.84.34.0-3.7-4.34.3-4.14.0-4.0-4.1-4.54.3-4.7-4.6-0.33.9
Liver weight, right2.03.36.2-2.40.90.90.7-0.50.40.40.5-2.40.2-1.82.41.9-2.1-2.32.3-2.02.1-2.0-2.0-2.52.1-2.4-2.50.12.1
Locomotor activity0.91.53.8-1.60.50.40.3-0.10.00.10.2-1.7-0.0-1.11.61.1-1.5-1.61.6-1.21.2-1.2-1.2-1.81.4-1.6-2.00.41.5
Locomotor testing distance0.50.82.0-1.20.50.50.4-0.40.30.30.4-1.20.3-0.91.30.9-1.2-1.21.2-0.90.7-0.8-0.9-1.20.9-0.9-1.4-0.40.8
Locomotor testing rearing5.48.312.8-3.52.62.52.3-2.12.02.02.1-3.51.8-3.23.63.2-3.3-3.53.5-3.23.0-3.1-3.2-3.53.1-2.8-3.5-1.11.8
Locomotion in novel chamber3.54.36.52.1-2.1-2.1-2.01.8-1.7-1.7-1.62.2-1.62.5-2.0-2.52.12.0-2.02.4-2.52.42.31.9-2.62.41.61.3-1.2
Locomotion in novel chamber post-restriction0.91.11.91.1-1.0-1.0-1.00.9-0.8-0.8-0.81.1-0.71.4-1.2-1.20.81.2-1.21.1-1.41.21.11.1-1.31.11.01.0-0.6
Fecal boli incidents, locomotor time 10.10.10.40.50.40.40.4-0.50.50.50.60.30.5-0.50.30.1-0.1-0.40.4-0.10.10.10.0-0.1-0.20.20.2-0.4-0.5
Change in fecal boli incidents, locomotor task2.01.93.20.8-1.7-1.8-1.81.7-1.7-1.7-1.70.9-1.71.7-1.3-1.51.01.4-1.41.5-1.31.31.30.8-1.10.60.71.60.2
Time >=10cm from walls, locomotor time 10.60.61.20.3-1.1-1.1-1.11.0-1.1-1.1-1.00.4-1.00.9-0.4-0.80.60.4-0.40.9-0.81.10.80.4-0.60.60.20.80.2
Bouts of movement, locomotor time 10.60.72.81.50.10.20.2-0.40.50.50.61.00.60.3-0.4-0.61.20.3-0.30.6-1.20.80.80.6-0.81.31.70.3-1.4
Total resting periods, locomotor time 11.41.54.42.1-0.6-0.5-0.40.3-0.1-0.1-0.11.7-0.10.9-1.1-1.21.81.0-1.01.2-1.81.41.31.3-1.41.62.10.3-1.5
Rest time, locomotor task time 10.91.03.90.41.11.21.3-1.41.51.51.60.21.5-0.80.60.30.2-0.70.7-0.1-0.2-0.1-0.20.2-0.00.70.9-2.0-1.3
Distance moved, locomotor task time 10.30.31.4-0.4-0.5-0.6-0.70.7-0.8-0.8-0.7-0.5-0.80.20.1-0.1-0.1-0.10.1-0.00.4-0.30.1-0.60.2-0.6-0.51.20.9
Vertical activity count, locomotor time 10.60.63.80.2-0.9-1.0-1.11.0-1.1-1.1-1.0-0.6-1.10.6-0.2-0.50.20.3-0.30.3-0.10.20.4-0.4-0.3-0.3-0.71.90.7
Time >=10cm from walls, locomotor time 20.40.41.00.5-0.9-0.9-0.90.9-1.0-0.9-1.00.7-1.00.5-0.6-0.50.40.5-0.50.5-0.60.70.50.4-0.30.00.00.70.5
Bouts of movement, locomotor time 21.41.55.11.6-0.7-0.7-0.60.4-0.3-0.3-0.31.4-0.21.3-1.2-1.31.51.2-1.21.4-1.51.31.31.4-1.31.82.30.1-1.3
Total resting periods, locomotor time 21.61.75.91.8-0.6-0.6-0.40.2-0.1-0.1-0.11.5-0.01.3-1.3-1.41.61.3-1.31.5-1.61.31.41.5-1.42.12.40.1-1.6
Rest time, locomotor task time 20.91.03.61.8-0.2-0.2-0.0-0.20.20.20.31.30.30.6-0.7-1.01.10.7-0.71.2-1.41.11.11.0-1.01.61.9-0.1-1.6
Distance moved, locomotor task time 21.01.12.7-1.10.80.80.6-0.50.50.50.4-1.20.3-1.31.11.2-1.1-1.11.1-1.41.6-1.3-1.1-1.41.2-1.7-1.00.21.1
Vertical activity count, locomotor time 20.70.72.0-0.70.60.50.4-0.30.30.30.2-1.40.2-1.00.80.9-0.9-0.80.8-1.01.1-0.9-0.9-1.10.8-1.4-1.30.70.9
Light reinforcement 10.61.01.4-0.61.21.21.1-1.11.11.11.1-1.01.0-1.21.11.1-1.1-1.11.1-1.11.1-1.2-1.1-1.11.1-0.6-0.5-0.00.2
Light reinforcement 20.40.52.0-0.8-0.2-0.2-0.30.4-0.5-0.5-0.5-0.6-0.6-0.40.50.6-0.9-0.50.5-0.70.5-0.7-0.7-0.80.9-1.2-1.10.61.4
Bone: marrow area2.04.39.7-1.42.72.82.9-2.93.03.02.9-1.53.0-2.01.61.8-1.8-1.61.6-1.51.6-1.6-1.5-0.91.20.0-0.0-3.1-1.3
Bone: maximum diameter2.75.17.7-2.32.32.32.2-2.02.02.02.0-2.51.8-2.52.52.5-2.8-2.52.5-2.52.3-2.5-2.5-2.42.4-2.0-2.1-1.01.0
Bone: maximum force1.62.74.1-1.42.02.02.0-2.02.02.02.0-1.52.0-1.81.71.6-1.8-1.61.6-1.51.3-1.5-1.5-1.21.3-0.6-0.7-1.9-0.3
Bone: maximum moment2.03.45.5-1.52.32.32.3-2.32.32.32.3-1.72.3-2.01.81.8-2.0-1.81.8-1.61.5-1.7-1.6-1.41.4-0.6-0.7-2.1-0.5
Mean time between licks in bursts0.20.30.90.3-0.6-0.7-0.70.7-0.8-0.7-0.7-0.0-0.80.20.0-0.30.5-0.00.00.2-0.60.20.2-0.3-0.1-0.3-0.30.90.6
Mean num. licks in bursts2.22.64.62.1-1.0-1.0-0.80.6-0.5-0.5-0.52.1-0.41.7-2.0-1.81.92.0-2.01.9-1.61.81.92.1-2.02.12.00.1-1.8
Cd content in liver0.10.10.40.20.50.50.5-0.60.60.60.60.00.6-0.1-0.00.1-0.10.0-0.0-0.00.10.0-0.00.1-0.10.30.5-0.1-0.6
Co content in liver0.80.91.90.9-0.6-0.6-0.50.4-0.3-0.3-0.41.3-0.31.1-1.3-1.01.21.3-1.31.0-1.21.11.01.4-1.01.11.3-0.1-0.9
Cu content in liver0.81.01.4-1.21.21.21.2-1.11.11.11.0-0.91.0-1.10.91.1-0.8-0.90.9-1.11.1-1.2-1.1-0.71.0-0.7-0.5-1.10.1
Fe content in liver0.30.40.7-0.80.50.50.4-0.30.30.30.3-0.80.3-0.70.70.7-0.5-0.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.7-0.30.6
K content in liver1.61.52.6-1.31.21.21.1-1.01.01.00.9-1.20.8-1.41.21.5-1.5-1.21.2-1.51.6-1.6-1.5-1.31.5-1.3-1.0-0.30.8
Mg content in liver0.80.81.6-1.10.50.40.3-0.20.10.10.1-1.00.0-0.91.01.0-1.0-1.01.0-1.11.2-1.2-1.1-1.21.1-1.3-1.30.21.2
Mn content in liver0.50.51.8-0.90.00.0-0.10.3-0.3-0.3-0.4-0.6-0.4-0.60.50.7-0.8-0.60.6-0.80.9-0.8-0.8-0.81.0-1.3-1.00.51.3
Na content in liver0.40.41.40.4-0.9-0.9-0.91.0-1.0-1.0-0.90.4-1.00.5-0.4-0.50.50.3-0.30.4-0.30.40.40.1-0.3-0.2-0.11.20.6
Rb content in liver0.60.71.2-0.80.91.00.9-0.90.90.90.8-0.70.8-0.90.70.9-0.9-0.70.7-0.91.1-1.0-0.9-0.70.8-0.6-0.4-0.90.2
Se content in liver2.22.78.7-1.90.10.1-0.20.5-0.6-0.6-0.7-1.7-0.9-1.31.61.6-1.5-1.61.6-1.81.8-1.8-1.8-2.22.1-2.8-2.51.72.9
Sr content in liver1.91.77.21.1-1.6-1.6-1.81.8-1.8-1.8-1.70.7-1.81.1-0.8-1.01.30.8-0.80.8-1.21.10.80.1-0.6-0.2-0.12.70.9
Zn content in liver0.20.31.2-0.8-0.1-0.1-0.20.4-0.4-0.4-0.5-0.5-0.5-0.30.40.5-0.3-0.40.4-0.50.3-0.4-0.5-0.60.7-1.0-0.70.31.1
Bone: minimum diameter2.64.99.5-1.52.93.03.0-3.13.13.13.0-1.73.1-2.31.82.1-2.2-1.81.8-1.91.6-1.9-1.9-1.31.5-0.4-0.5-2.4-1.1
Time in familiar zone, hab. session 11.81.74.4-0.31.81.81.9-2.02.12.12.0-0.62.1-1.10.70.9-0.4-0.70.7-0.81.0-0.8-0.8-0.40.60.50.6-1.6-1.3
Time in novel zone, hab. session 10.70.73.0-0.9-0.8-0.8-0.91.1-1.2-1.2-1.2-0.5-1.3-0.00.30.2-0.6-0.30.3-0.30.1-0.3-0.3-0.60.5-1.3-1.40.71.7
Total zone transitions, hab. session 11.31.84.2-0.81.81.81.9-2.02.02.02.1-0.92.1-1.31.11.1-0.5-1.01.0-0.91.1-0.9-0.9-0.60.70.1-0.1-1.6-1.1
Total locomotion distance, hab. session 10.20.31.40.50.60.60.7-0.80.90.90.90.20.9-0.1-0.1-0.10.40.1-0.10.2-0.00.20.20.2-0.30.80.6-0.2-1.2
Locomotion velocity, hab. session 10.40.52.11.00.10.10.2-0.40.40.40.50.80.50.5-0.6-0.70.90.6-0.60.8-0.60.80.80.8-0.91.31.0-0.1-1.4
Time in familiar zone, hab. session 20.50.52.0-0.40.80.91.0-1.01.01.01.0-0.21.1-0.50.30.4-0.6-0.30.3-0.30.4-0.3-0.30.10.30.40.5-1.4-0.7
Time in novel zone, hab. session 20.20.20.7-0.1-0.5-0.5-0.60.7-0.7-0.7-0.7-0.1-0.80.2-0.1-0.00.30.0-0.0-0.1-0.1-0.1-0.1-0.30.1-0.6-0.60.80.8
Total zone transitions, hab. session 22.53.36.3-1.22.42.42.4-2.42.52.52.5-1.62.4-2.01.81.7-1.3-1.71.7-1.51.8-1.5-1.5-1.41.3-0.4-0.6-1.5-0.8
Total locomotion distance, hab. session 20.20.20.80.90.10.10.1-0.30.30.30.40.40.40.2-0.3-0.40.50.3-0.30.4-0.30.40.40.3-0.50.90.60.3-0.9
Locomotion velocity, hab. session 20.10.10.60.80.20.20.2-0.30.40.30.40.30.40.1-0.2-0.30.40.2-0.20.3-0.10.30.30.1-0.40.70.40.4-0.7
Novel to familiar place preference ratio0.50.51.0-0.70.70.60.6-0.50.50.50.5-0.80.4-0.80.80.8-1.0-0.80.8-0.90.6-0.9-0.9-0.90.9-0.8-0.90.20.5
Novelty place preference0.60.61.0-0.80.80.80.7-0.70.70.70.6-0.70.6-0.80.70.9-1.0-0.70.7-0.90.6-0.9-0.9-0.80.9-0.7-0.8-0.20.3
Time in novel zone, NPP test0.60.61.2-0.80.80.80.8-0.70.70.70.7-0.80.6-0.90.80.9-1.1-0.80.8-0.90.6-0.9-0.9-0.80.9-0.7-0.8-0.20.4
Total zone transitions, NPP test0.50.71.1-0.70.90.90.9-0.90.90.90.9-0.90.8-1.01.00.9-0.6-1.01.0-0.90.9-0.8-0.9-1.00.8-0.6-0.7-0.20.2
Total locomotion distance, NPP test0.10.20.5-0.10.40.30.3-0.30.30.30.4-0.50.3-0.50.60.4-0.3-0.60.6-0.40.5-0.4-0.4-0.70.4-0.3-0.60.60.2
Locomotion velocity, NPP test0.20.30.6-0.20.60.50.5-0.50.50.50.6-0.60.5-0.60.70.5-0.3-0.70.7-0.50.7-0.5-0.5-0.80.5-0.3-0.60.50.1
Intraocular pressure0.00.10.30.10.20.20.2-0.30.30.30.20.10.30.0-0.1-0.10.10.0-0.00.2-0.10.30.20.2-0.30.40.2-0.5-0.5
Delta distance traveled before/after self-admin0.60.61.91.4-0.8-0.8-0.80.7-0.7-0.7-0.70.9-0.70.5-0.9-0.90.90.8-0.80.8-0.60.90.90.5-0.80.50.71.0-0.3
Delta ambulatory time before/after self-admin0.80.91.91.4-0.9-1.0-1.00.9-0.8-0.9-0.90.9-0.80.8-1.1-1.11.01.1-1.11.0-0.81.11.10.8-1.00.71.01.1-0.3
Parametrial fat weight3.56.813.21.9-3.4-3.4-3.53.6-3.6-3.6-3.62.0-3.62.6-2.2-2.32.42.2-2.22.1-1.92.12.11.4-1.70.30.53.41.3
Pavlov. Cond. lever latency0.50.71.30.9-0.6-0.6-0.50.5-0.4-0.4-0.50.9-0.41.0-1.0-0.91.11.0-1.00.9-1.10.90.91.1-0.81.00.8-0.3-0.6
Pavlov. Cond. magazine entry latency0.60.71.9-0.90.10.1-0.10.2-0.2-0.2-0.1-1.0-0.3-0.81.10.7-1.0-1.11.1-0.80.8-0.8-0.8-1.30.9-1.4-1.41.01.3
Pavlov. Cond. change in total contacts0.10.10.40.3-0.3-0.3-0.30.3-0.3-0.3-0.20.2-0.30.1-0.1-0.30.10.1-0.10.3-0.20.30.30.0-0.3-0.10.10.7-0.0
Pavlov. Cond. index score0.81.02.3-1.10.40.40.2-0.10.10.10.2-1.2-0.0-1.11.41.0-1.2-1.41.4-1.01.1-1.0-1.0-1.51.0-1.5-1.50.91.2
Pavlov. Cond. latency score0.40.51.2-0.70.10.1-0.00.1-0.1-0.1-0.0-0.8-0.2-0.70.90.6-0.9-0.90.9-0.60.7-0.6-0.6-1.10.6-1.1-1.01.00.9
Pavlov. Cond. lever contacts0.80.91.7-1.10.60.60.4-0.40.30.30.4-1.10.2-1.11.21.0-1.2-1.21.2-1.01.2-0.9-1.0-1.31.0-1.3-1.20.40.9
Pavlov. Cond. magazine entry number0.60.71.60.8-0.5-0.4-0.30.2-0.2-0.2-0.31.0-0.11.0-1.1-0.81.01.1-1.10.9-0.90.80.91.3-0.91.21.1-0.6-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.80.50.10.10.2-0.30.30.30.30.40.40.3-0.4-0.40.50.4-0.40.4-0.40.50.40.6-0.50.70.6-0.5-0.9
Pavlov. Cond. lever-magazine prob. diff.1.01.22.7-1.20.50.40.2-0.10.10.10.2-1.3-0.0-1.21.41.0-1.3-1.51.5-1.11.2-1.0-1.1-1.61.2-1.6-1.60.81.3
Pavlov. Cond. response bias2.22.65.0-1.91.01.00.8-0.60.50.50.7-2.00.4-1.82.21.7-1.8-2.22.2-1.81.9-1.7-1.8-2.21.8-2.1-2.20.41.7
Pavlov. Cond. lever latency0.10.21.7-0.20.20.30.4-0.40.40.40.30.50.40.2-0.5-0.0-0.20.5-0.50.1-0.00.10.10.7-0.20.40.5-1.3-0.6
Pavlov. Cond. magazine entry latency0.40.52.10.5-0.9-0.9-1.01.0-1.0-1.0-1.00.1-1.10.4-0.1-0.50.40.1-0.10.4-0.40.40.4-0.1-0.2-0.2-0.21.40.7
Pavlov. Cond. change in total contacts0.20.20.90.50.50.50.6-0.70.70.70.80.00.8-0.20.1-0.10.2-0.10.10.1-0.20.10.10.1-0.30.70.6-0.2-1.0
Pavlov. Cond. index score0.10.10.70.1-0.1-0.1-0.20.2-0.2-0.2-0.1-0.4-0.2-0.20.50.10.0-0.50.5-0.10.0-0.1-0.1-0.60.1-0.3-0.40.80.4
Pavlov. Cond. latency score0.20.21.50.6-0.6-0.6-0.70.6-0.6-0.6-0.5-0.0-0.60.20.1-0.40.4-0.10.10.3-0.40.30.3-0.2-0.2-0.0-0.11.20.3
Pavlov. Cond. lever contacts0.40.51.3-0.40.50.50.4-0.40.40.40.5-1.00.3-0.81.10.6-0.4-1.11.1-0.70.7-0.7-0.7-1.10.7-0.7-0.80.60.5
Pavlov. Cond. magazine entry number0.30.40.6-0.80.70.70.7-0.70.60.60.6-0.50.6-0.60.50.7-0.7-0.50.5-0.60.8-0.7-0.6-0.40.6-0.4-0.5-0.80.1
Pavlov. Cond. intertrial magazine entries2.12.77.1-1.22.22.22.3-2.42.42.42.4-1.02.4-1.51.21.3-1.1-1.11.1-1.11.2-1.2-1.1-0.50.80.1-0.1-2.7-1.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.00.10.1-0.00.0-0.0-0.00.1-0.5-0.0-0.40.60.2-0.1-0.60.6-0.30.2-0.3-0.3-0.70.3-0.4-0.50.70.4
Pavlov. Cond. response bias0.40.61.0-0.40.90.80.8-0.80.80.80.9-0.90.8-0.91.00.7-0.5-1.01.0-0.70.7-0.7-0.7-0.90.6-0.4-0.4-0.1-0.0
Time in closed arm before self-admin0.10.10.5-0.7-0.1-0.1-0.10.2-0.2-0.2-0.2-0.2-0.2-0.10.20.3-0.2-0.20.2-0.2-0.1-0.2-0.2-0.10.3-0.5-0.5-0.30.5
Time in closed arm after self-admin0.00.00.1-0.4-0.2-0.2-0.20.2-0.3-0.3-0.2-0.2-0.30.10.3-0.0-0.0-0.30.30.0-0.20.00.1-0.0-0.1-0.2-0.2-0.20.3
Time in open arm before self-admin0.10.10.70.90.30.30.3-0.40.50.50.50.20.5-0.40.3-0.10.1-0.30.30.10.1-0.00.1-0.2-0.10.50.50.1-0.6
Time in open arm after self-admin0.10.10.40.30.50.50.5-0.60.60.60.50.00.6-0.40.10.2-0.1-0.10.1-0.20.3-0.1-0.2-0.10.20.10.10.0-0.4
Bone: periosteal estimation2.04.27.3-1.52.62.62.7-2.72.72.72.7-1.82.7-2.11.81.9-1.9-1.81.8-1.81.6-1.8-1.8-1.31.5-0.5-0.6-2.5-0.8
Bone: periosteal perimeter2.13.46.5-1.42.42.52.5-2.52.52.52.5-1.52.6-1.91.51.7-1.8-1.51.5-1.61.4-1.6-1.6-1.01.3-0.4-0.5-2.2-0.8
Bone: post-yield work0.91.34.7-0.91.41.41.5-1.51.51.51.6-0.91.6-1.11.00.8-0.8-1.01.0-0.70.7-0.7-0.7-0.40.50.1-0.2-2.2-0.8
Progressive ratio test 1 active lever presses1.31.42.9-1.31.61.61.6-1.71.71.71.6-1.31.7-0.80.81.1-0.9-0.70.7-1.01.0-1.1-0.9-0.60.9-0.0-0.3-1.3-0.6
Progressive ratio test 1 breakpoint1.11.12.4-1.11.41.51.5-1.51.51.51.5-1.11.6-0.70.71.0-0.7-0.50.5-1.00.9-0.9-0.9-0.40.80.0-0.2-1.2-0.6
Progressive ratio test 1 inactive lever presses3.94.36.3-2.52.52.52.5-2.42.32.42.2-2.32.3-1.91.92.4-2.0-1.81.8-2.22.0-2.3-2.2-1.52.1-1.0-1.1-1.90.2
Progressive ratio test 2 active lever presses0.30.41.9-1.40.30.30.3-0.20.10.20.2-1.00.2-0.40.80.6-0.5-0.70.7-0.40.5-0.6-0.3-0.70.8-0.7-0.9-0.40.5
Progressive ratio test 2 breakpoint0.30.41.9-1.40.40.40.4-0.40.30.30.3-1.00.3-0.40.70.6-0.5-0.70.7-0.40.5-0.7-0.4-0.60.8-0.6-0.8-0.60.5
Progressive ratio test 2 inactive lever presses1.72.04.8-2.21.41.41.4-1.31.21.31.3-1.91.2-1.31.71.5-1.4-1.61.6-1.21.3-1.5-1.2-1.41.4-1.0-1.2-1.20.4
Incentive Sensitization - Responses0.40.41.6-1.20.50.50.5-0.40.40.40.4-0.70.4-0.50.70.7-0.4-0.70.7-0.50.5-0.6-0.5-0.50.8-0.6-0.6-1.10.4
Incentive Sensitization - Breakpoint0.30.31.6-1.30.30.30.3-0.20.10.10.2-0.60.1-0.40.60.6-0.4-0.60.6-0.40.5-0.6-0.4-0.50.7-0.7-0.7-0.90.6
Sum of active levers in priming session hrs 5-62.52.44.22.0-1.7-1.7-1.61.5-1.4-1.5-1.41.6-1.41.8-1.7-1.82.01.6-1.61.4-1.51.71.51.4-1.61.51.21.3-0.5
Progressive ratio0.20.20.80.70.10.10.0-0.10.20.20.10.50.20.3-0.8-0.20.40.8-0.80.10.20.10.00.5-0.30.40.90.6-0.5
Food seeking constrained by brief footshock1.11.46.91.80.50.40.5-1.01.11.01.30.31.30.3-0.3-1.10.60.4-0.41.3-0.81.11.30.3-1.42.02.00.9-2.6
Seeking ratio, punishment vs. effort0.30.31.60.50.40.30.4-0.60.60.60.8-0.20.8-0.10.5-0.40.1-0.40.40.7-0.70.50.8-0.1-0.50.90.5-0.3-1.2
Retroperitoneal fat weight3.511.522.32.4-4.5-4.5-4.64.7-4.7-4.7-4.72.2-4.73.5-2.7-3.12.72.7-2.72.8-2.92.92.81.7-2.30.70.84.41.7
Reaction time number correct1.42.03.6-1.21.21.21.0-0.90.80.80.8-1.70.7-1.61.51.6-1.8-1.51.5-1.71.7-1.7-1.7-1.91.7-1.7-1.70.51.2
Reaction time mean minus median0.30.40.80.5-0.5-0.5-0.40.3-0.3-0.3-0.30.6-0.30.6-0.6-0.70.60.6-0.60.7-0.70.80.70.8-0.80.80.9-0.2-0.6
Reaction time mean minus median AUC0.00.00.1-0.20.10.10.1-0.10.10.10.1-0.20.1-0.00.1-0.0-0.1-0.10.10.10.00.10.10.1-0.10.10.2-0.4-0.2
Reaction time num false alarms3.44.68.9-2.71.31.31.0-0.80.60.70.8-2.90.5-2.22.82.3-2.2-2.82.8-2.52.0-2.3-2.5-3.02.5-2.8-2.90.62.4
Reaction time num false alarms AUC2.73.77.6-2.31.11.10.8-0.60.50.60.7-2.60.4-2.02.52.1-2.0-2.52.5-2.21.8-2.1-2.2-2.72.2-2.5-2.70.92.2
Reaction time trials correct on left1.42.03.6-1.21.21.21.0-0.90.80.80.8-1.70.7-1.61.51.6-1.8-1.51.5-1.71.7-1.7-1.7-1.91.7-1.7-1.70.51.2
Reaction time trials on left1.42.13.7-1.31.21.21.0-0.90.80.80.8-1.80.7-1.61.61.6-1.8-1.61.6-1.71.8-1.7-1.7-1.91.7-1.8-1.70.51.2
Reaction time mean0.81.22.30.9-0.8-0.8-0.60.5-0.5-0.5-0.41.2-0.31.1-1.1-1.31.41.1-1.11.4-1.21.31.41.5-1.41.51.5-0.8-1.1
Reaction time mean AUC1.01.42.20.9-1.2-1.2-1.00.9-0.9-0.9-0.91.2-0.81.4-1.2-1.41.51.2-1.21.5-1.31.41.51.5-1.41.31.3-0.4-0.8
Median of all reaction times0.81.12.00.9-0.8-0.8-0.60.5-0.5-0.5-0.51.1-0.41.1-1.0-1.21.41.0-1.01.3-1.21.31.31.4-1.31.41.4-0.6-1.0
Reaction time omissions0.20.20.7-0.70.10.10.00.0-0.1-0.00.1-0.8-0.1-0.40.80.3-0.5-0.80.8-0.40.5-0.3-0.4-0.80.4-0.5-0.50.10.5
Reaction time false alarm rate0.40.61.4-1.10.10.10.00.1-0.2-0.1-0.0-1.1-0.2-0.61.10.7-0.5-1.11.1-0.70.4-0.7-0.7-1.10.8-1.0-1.20.61.1
Reaction time premature initiation rate1.92.54.82.2-1.4-1.3-1.21.1-1.0-1.0-1.02.0-0.91.7-1.9-1.81.71.9-1.91.8-1.71.71.81.9-1.81.81.70.3-1.1
Reaction time premature initiations0.50.82.31.5-0.8-0.8-0.80.7-0.6-0.6-0.71.1-0.60.9-1.1-1.00.71.1-1.10.9-0.80.90.90.9-0.90.90.80.6-0.5
Std. dev. reaction times0.40.61.10.6-0.7-0.7-0.50.5-0.5-0.5-0.40.8-0.40.9-0.7-0.91.00.7-0.71.0-1.01.01.01.0-1.01.01.0-0.4-0.7
Reaction time trials completed1.42.13.7-1.31.21.21.0-0.90.80.80.8-1.80.7-1.61.61.6-1.8-1.61.6-1.71.8-1.7-1.7-1.91.7-1.8-1.70.51.2
Reaction time trials AUC1.72.54.6-1.41.31.21.0-0.90.90.80.9-2.00.7-1.81.81.8-2.0-1.81.8-1.91.9-1.8-1.9-2.11.9-2.0-1.90.51.4
Run reversals in cocaine runway, females2.01.92.91.2-1.6-1.6-1.51.4-1.4-1.4-1.31.5-1.31.4-1.4-1.71.51.3-1.31.5-1.71.61.51.4-1.61.11.00.4-0.5
Run reversals in cocaine runway, males1.41.43.2-1.81.11.11.0-0.90.80.80.9-1.50.8-1.41.51.3-1.3-1.41.4-1.11.1-1.3-1.1-1.31.4-1.3-0.8-0.80.6
Latency to leave start box in cocaine runway0.40.41.50.7-0.4-0.4-0.30.4-0.3-0.4-0.51.0-0.30.5-1.2-0.60.51.2-1.20.4-0.50.60.31.1-0.60.10.6-0.1-0.4
Latency to leave start box in cocaine runway, F0.20.20.40.6-0.4-0.4-0.40.4-0.4-0.4-0.40.6-0.40.3-0.6-0.40.60.6-0.60.1-0.40.50.10.5-0.50.10.40.2-0.1
Latency to leave start box in cocaine runway, M0.40.40.8-0.70.70.70.7-0.70.70.60.4-0.30.6-0.5-0.40.7-0.70.4-0.4-0.50.7-0.6-0.50.30.7-0.8-0.2-0.9-0.0
Std. dev. time between licks in bursts0.81.01.9-0.90.90.90.8-0.80.70.70.8-1.30.7-1.21.41.1-0.8-1.41.4-1.11.0-1.1-1.1-1.41.1-1.0-1.0-0.00.6
Total sessions with >9 infusions2.52.85.1-2.21.81.81.8-1.61.51.51.5-2.11.5-1.81.71.9-1.8-1.61.6-1.81.9-1.9-1.7-1.41.8-1.6-0.7-1.50.6
Short access day 1 total inactive lever presses0.80.92.4-1.60.70.70.6-0.40.40.40.3-1.00.3-1.00.91.2-1.0-0.90.9-1.11.1-1.2-1.1-0.81.0-1.4-1.5-0.81.0
Short access day 10 total inactive lever presses0.50.51.50.8-0.4-0.3-0.20.2-0.2-0.2-0.41.1-0.20.8-1.1-0.60.71.1-1.10.6-0.40.50.71.2-0.61.01.2-0.6-0.5
Short access day 1 total infusions0.40.41.1-0.90.70.70.7-0.70.60.60.7-1.00.6-0.60.60.6-0.6-0.50.5-0.60.6-0.7-0.7-0.50.4-0.4-0.3-0.30.0
Short access day 10 total infusions1.01.14.7-2.20.50.50.4-0.20.10.10.0-1.60.0-0.40.81.2-1.3-0.60.6-1.31.2-1.3-1.3-1.01.3-1.5-1.8-0.21.4
Short access total infusions0.20.20.8-0.9-0.2-0.2-0.30.3-0.4-0.4-0.4-0.9-0.40.30.10.1-0.40.1-0.1-0.20.2-0.3-0.1-0.30.2-0.6-0.60.60.6
Short access day 1 locomotion0.50.51.5-1.00.80.80.9-0.80.80.80.8-0.70.8-0.60.50.8-0.5-0.50.5-0.70.6-0.7-0.7-0.30.7-0.3-0.3-1.2-0.0
Short access day 10 total locomotion0.80.82.61.1-0.4-0.3-0.20.1-0.1-0.1-0.21.3-0.00.9-1.3-0.90.91.3-1.30.9-1.00.81.11.3-0.81.31.6-0.3-1.1
Short access total locomotion0.30.30.80.5-0.4-0.3-0.30.3-0.3-0.3-0.40.5-0.20.7-0.8-0.50.40.9-0.90.5-0.60.40.70.7-0.30.50.80.4-0.4
One hour access (0.3 mA shock)0.20.21.5-1.10.30.30.4-0.40.40.40.5-0.60.50.10.30.1-0.1-0.20.2-0.00.0-0.0-0.10.1-0.00.3-0.1-1.2-0.3
Compulsive drug intake0.20.20.40.30.50.60.6-0.60.60.60.40.50.6-0.3-0.50.2-0.20.4-0.40.10.4-0.1-0.00.50.00.20.1-0.6-0.5
One hour access (shock baseline)0.70.84.9-2.20.10.10.00.1-0.3-0.2-0.1-1.5-0.3-0.31.10.8-0.8-1.01.0-0.80.5-0.7-0.9-0.90.9-1.2-1.3-0.71.3
Social response proportion0.60.61.6-1.20.40.40.3-0.20.10.10.1-0.90.1-0.80.90.8-1.1-0.90.9-0.90.6-0.8-0.9-0.91.0-1.2-1.2-0.21.0
Social responses2.83.64.9-2.22.12.12.0-1.91.81.91.8-1.91.8-2.12.02.2-2.0-1.91.9-2.11.7-2.1-2.1-1.62.1-1.5-1.7-1.60.6
Social time1.31.74.9-0.31.81.81.9-2.12.22.22.2-0.62.2-1.10.80.8-0.7-0.80.8-0.60.6-0.7-0.6-0.40.30.60.2-1.4-1.5
Soleus weight0.10.41.0-0.80.40.40.3-0.20.20.20.1-0.80.1-0.60.60.8-0.6-0.60.6-0.80.9-0.8-0.8-0.80.9-1.0-0.80.40.8
Bone: stiffness2.64.25.9-2.22.22.22.2-2.12.02.02.1-2.32.0-2.32.32.2-2.4-2.32.3-2.11.9-2.1-2.1-1.92.0-1.4-1.4-1.80.4
Tibialis anterior weight1.24.010.7-2.10.30.2-0.20.4-0.6-0.6-0.5-2.4-0.8-1.62.31.9-1.9-2.32.3-2.12.1-1.9-2.1-3.02.4-3.2-3.12.03.3
Time to tail flick, vehicle, before self-admin0.20.20.40.10.50.50.5-0.50.60.60.6-0.10.6-0.50.30.1-0.3-0.40.4-0.3-0.00.1-0.2-0.1-0.20.10.4-0.5-0.5
Time to tail flick, vehicle, after self-admin0.20.20.5-0.1-0.5-0.5-0.40.4-0.5-0.5-0.30.4-0.40.3-0.2-0.40.20.2-0.20.7-0.60.30.70.4-0.30.10.5-0.7-0.0
Time to tail flick, test, before self-admin0.80.83.91.30.80.70.8-1.11.21.21.20.51.30.1-0.4-0.40.20.4-0.40.4-0.40.50.40.5-0.71.51.50.0-2.0
Time to tail flick, test, after self-admin0.00.00.10.1-0.0-0.0-0.00.1-0.1-0.1-0.10.1-0.1-0.40.20.0-0.1-0.20.2-0.0-0.1-0.10.0-0.3-0.0-0.30.10.10.1
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.1-0.7-0.7-0.70.8-0.9-0.8-0.80.4-0.90.5-0.5-0.20.20.6-0.60.4-0.20.00.40.40.1-0.3-0.20.00.7
Delta time to tail flick, test, before/after SA0.40.31.4-0.6-0.6-0.6-0.70.8-0.9-0.9-0.9-0.2-0.90.00.10.10.0-0.10.1-0.1-0.0-0.1-0.0-0.10.3-0.9-0.7-0.01.2
Tibia length4.111.616.6-3.04.14.14.0-3.93.93.93.9-3.33.8-3.83.53.6-3.9-3.43.4-3.43.4-3.5-3.4-2.93.1-1.9-1.9-2.7-0.1
Ambulatory time before self-admin1.31.43.7-0.21.61.61.6-1.71.81.81.9-0.71.8-1.11.10.8-0.7-1.11.1-0.80.7-0.8-0.9-0.80.50.3-0.2-0.9-1.0
Ambulatory time after self-admin0.70.83.41.20.70.60.7-1.01.11.11.30.51.20.1-0.2-0.50.80.2-0.20.5-0.30.50.50.3-0.81.51.4-0.2-1.8
Bone: tissue strength0.10.11.00.7-0.2-0.2-0.20.2-0.1-0.1-0.10.1-0.10.2-0.1-0.30.30.1-0.10.2-0.40.20.2-0.0-0.20.20.21.0-0.2
Total heroin consumption0.60.72.40.2-1.1-1.1-1.21.2-1.2-1.2-1.10.0-1.21.1-0.3-0.70.30.4-0.40.5-0.70.60.60.1-0.40.1-0.41.60.6
Bone: trabecular number0.20.31.10.80.10.10.2-0.30.30.30.30.70.40.4-0.7-0.50.40.7-0.70.5-0.40.50.50.7-0.60.90.8-0.0-1.0
Bone: trabecular spacing0.10.20.4-0.30.00.0-0.00.1-0.1-0.1-0.0-0.5-0.1-0.30.60.30.2-0.60.6-0.40.3-0.3-0.4-0.60.4-0.5-0.60.30.6
Bone: trabecular thickness0.10.10.4-0.50.20.20.2-0.10.10.10.0-0.30.0-0.20.10.4-0.7-0.10.1-0.40.5-0.4-0.4-0.20.4-0.5-0.6-0.30.4
Bone: trabecular tissue density0.91.34.1-0.2-1.6-1.6-1.71.9-2.0-1.9-1.90.2-2.00.8-0.3-0.50.60.3-0.30.4-0.50.50.40.1-0.1-0.8-0.61.01.7
Water consumed over 24 hours0.30.31.20.30.60.60.7-0.80.80.80.90.10.9-0.20.1-0.10.4-0.00.00.2-0.30.10.20.3-0.30.70.5-0.8-1.1
Number of responses in last shaping day0.30.31.9-1.40.10.10.00.1-0.2-0.2-0.1-0.8-0.2-0.50.60.5-0.6-0.60.6-0.40.5-0.5-0.5-0.50.6-1.0-0.6-0.60.8