Hub : Genes

Lhfpl5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Lhfpl5 0.27 0.11 5.2e-14 0.28 0.3 0.31 0.31 1.9e-12 4.0e-13 1.3e-13 1.8e-13
2 Brain mRNA stability Lhfpl5 0.02 0.01 6.3e-03 0.01 0.01 0.01 0 3.7e-02 1.5e-02 4.5e-02 1.2e-01
3 OFC gene expression Lhfpl5 0.4 0.14 1.4e-09 0.35 0.39 0.39 0.39 2.8e-09 2.9e-10 3.5e-10 3.0e-10
4 IL gene expression Lhfpl5 0.4 0.13 6.5e-10 0.21 0.25 0.23 0.24 8.3e-06 8.8e-07 2.4e-06 1.5e-06
5 RMTg gene expression Lhfpl5 0.11 0.07 1.3e-03 0.09 0.09 0.08 0.07 2.2e-03 1.9e-03 4.2e-03 5.4e-03
6 Brain gene expression Lhfpl5 0.28 0.1 0.0e+00 0.29 0.27 0.29 0.29 1.0e-27 1.5e-25 1.6e-27 2.7e-27
7 PL gene expression Lhfpl5 0.33 0.11 0.0e+00 0.44 0.46 0.46 0.46 1.7e-52 2.5e-56 5.4e-56 1.6e-56
8 pVTA gene expression Lhfpl5 0.19 0.09 8.3e-16 0.15 0.16 0.16 0.16 3.1e-12 1.1e-12 7.1e-13 1.5e-12
9 BLA gene expression Lhfpl5 0.17 0.09 1.5e-07 0.12 0.11 0.1 0.1 5.8e-07 1.5e-06 3.7e-06 5.7e-06
10 NAcc gene expression Lhfpl5 0.28 0.11 0.0e+00 0.24 0.26 0.27 0.28 5.7e-36 1.9e-39 1.4e-40 4.6e-42
11 LHb gene expression Lhfpl5 0.29 0.16 1.6e-04 0.15 0.13 0.15 0.12 2.0e-04 4.9e-04 1.9e-04 7.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.40.71.1-0.60.60.90.60.6-1.00.9-0.9-1.00.9-0.8
Area under the delay curve0.20.30.60.7-0.7-0.6-0.4-0.70.4-0.70.50.4-0.5-0.2
BMI with tail1.96.514.22.3-2.2-2.3-2.6-2.82.2-2.42.52.3-2.23.8
BMI without tail1.15.86.42.2-2.2-2.4-2.4-2.52.5-2.52.52.4-2.32.5
Body weight4.720.625.34.8-5.0-5.0-4.2-4.74.6-5.04.74.6-4.81.4
Weight adjusted by age0.10.20.50.5-0.7-0.4-0.2-0.60.1-0.60.40.1-0.30.7
Bone surface0.20.43.70.2-0.3-0.10.10.0-0.2-0.1-0.1-0.2-0.0-1.9
Bone volume0.10.21.40.3-0.4-0.3-0.2-0.30.1-0.30.20.0-0.2-1.2
Breakpoint value in progressive ratio session0.00.00.30.4-0.1-0.0-0.5-0.20.10.10.10.10.00.1
Number of licking bursts0.10.30.7-0.80.70.40.70.8-0.30.5-0.6-0.50.40.1
Context. condit. distance diff. score0.80.93.0-0.80.60.61.01.0-0.80.8-1.0-0.90.7-1.7
Locomotion velocity, session 11.11.22.3-1.41.11.01.51.2-1.10.9-1.2-1.01.1-0.3
Locomotion distance, session 13.34.26.1-2.52.32.22.22.2-2.02.0-2.1-1.92.1-0.0
Locomotion velocity, session 20.30.30.5-0.60.50.40.60.7-0.60.6-0.7-0.50.60.2
Locomotion distance, session 21.11.51.9-1.31.31.21.31.2-1.41.2-1.3-1.31.3-0.3
Locomotion velocity, session 30.40.52.20.0-0.2-0.8-0.2-0.40.6-0.70.50.6-0.81.5
Locomotion distance, session 30.40.41.2-1.10.90.40.80.7-0.40.5-0.5-0.40.50.6
Stereotopy head waving bouts, day 31.92.33.51.5-1.6-1.7-1.1-1.21.9-1.71.51.9-1.60.3
Stereotopy head waving duration, day 30.10.10.20.4-0.4-0.3-0.0-0.10.4-0.30.20.4-0.30.2
Locomotion velocity, session 70.40.41.1-0.60.50.50.80.4-1.10.5-0.8-0.90.50.2
Locomotion distance, session 71.41.92.9-1.41.21.31.61.2-1.71.3-1.5-1.61.2-0.4
Stereotopy head waving bouts, day 71.31.52.80.7-0.8-1.4-0.7-0.91.7-1.41.31.6-1.41.1
Stereotopy head waving duration, day 71.51.93.10.9-1.0-1.4-1.0-1.01.8-1.51.41.7-1.41.5
Locomotion velocity, session 80.40.54.1-0.20.00.00.60.6-0.30.2-0.5-0.20.1-2.0
Locomotion distance, session 81.31.92.9-1.41.21.11.51.5-1.31.3-1.5-1.31.2-1.7
Degree of sensitization distance0.30.31.90.5-0.40.30.0-0.0-0.60.3-0.3-0.60.2-1.4
Degree of sensitization stereotypy0.20.21.4-0.30.2-0.30.10.00.6-0.30.30.5-0.31.2
Conditioned locomotion3.03.54.92.2-2.1-2.0-2.1-1.91.8-1.81.91.8-1.8-0.3
Cocaine response after cond. corrected0.40.60.90.8-0.8-0.8-1.0-0.90.7-0.70.80.6-0.90.0
Cocaine response after cond. not corrected0.40.60.90.8-0.8-0.9-0.8-0.70.7-0.70.80.6-1.0-0.5
Cocaine response before conditioning0.10.10.90.0-0.1-0.10.30.20.0-0.1-0.10.1-0.1-1.0
Saline control response0.60.91.71.3-1.0-0.6-1.3-1.20.6-0.71.00.7-0.70.6
Bone: connectivity density0.40.71.4-0.40.40.70.50.5-1.10.9-0.9-1.20.8-0.9
Bone: cortical apparent density0.10.10.40.3-0.1-0.1-0.6-0.40.1-0.10.30.0-0.2-0.3
Bone: cortical area0.00.00.3-0.20.0-0.10.2-0.1-0.1-0.1-0.1-0.1-0.10.5
Bone: cortical porosity0.20.31.2-0.60.50.30.80.5-0.10.1-0.3-0.10.31.1
Bone: cortical porosity0.30.31.0-0.60.50.51.00.5-0.40.3-0.5-0.40.50.8
Bone: cortical thickness0.71.14.2-1.21.20.90.80.6-0.80.8-0.7-0.90.82.1
Bone: cortical thickness0.40.55.20.20.00.1-0.5-0.50.1-0.00.30.10.12.3
Bone: cortical tissue density0.10.10.40.4-0.2-0.2-0.6-0.50.2-0.20.30.1-0.3-0.4
Condit. Reinf. active minus inactive responses0.91.01.8-0.60.71.21.00.9-1.21.0-1.0-1.41.1-0.4
Condit. Reinf. active-inactive response ratio0.00.00.10.4-0.10.2-0.2-0.10.00.10.2-0.10.10.2
Condit. Reinf. active responses0.20.20.7-0.10.20.60.40.2-0.80.5-0.5-0.90.50.0
Condit. Reinf. inactive responses0.20.30.7-0.40.40.60.40.2-0.90.5-0.6-0.70.60.4
Incentive salience index mean0.40.50.9-0.50.50.70.90.7-0.80.6-0.7-0.90.6-0.3
Condit. Reinf. lever presses0.10.10.3-0.30.10.10.60.4-0.30.1-0.3-0.40.0-0.1
Condit. Reinf. active minus inactive responses0.30.51.1-0.50.60.80.80.9-0.50.7-0.7-0.70.7-1.1
Condit. Reinf. active-inactive response ratio0.10.21.3-0.10.20.40.40.5-0.10.2-0.2-0.20.3-1.2
Condit. Reinf. active responses0.50.70.9-0.70.71.01.01.0-0.90.9-0.9-0.70.8-0.4
Condit. Reinf. inactive responses0.00.10.60.1-0.1-0.1-0.0-0.1-0.10.0-0.10.0-0.10.8
Condit. Reinf. lever presses3.45.06.6-2.12.22.62.22.4-2.42.5-2.4-2.32.3-0.6
Condit. Reinf. lever reinforcers received1.11.52.0-1.21.21.41.41.4-1.31.3-1.3-1.11.2-0.2
Conditioned reinforcement - actives0.00.10.30.1-0.3-0.50.0-0.40.3-0.60.30.2-0.50.4
Conditioned reinforcement - inactives0.00.10.2-0.50.30.20.40.30.00.1-0.10.00.10.3
Conditioned locomotion0.40.61.10.9-1.1-0.9-0.5-1.00.4-0.90.70.6-0.9-0.2
Patch foraging indifference point 0 sec0.20.71.00.7-0.6-0.7-0.8-0.81.0-0.80.90.9-0.90.8
Patch foraging indifference point AUC0.10.20.7-0.40.40.30.50.7-0.30.3-0.5-0.10.4-0.8
Delay disc. indifference point, 0s delay0.10.10.3-0.10.00.00.2-0.0-0.50.2-0.3-0.50.20.1
Delay disc. indifference point, 16s delay0.10.10.50.1-0.3-0.30.1-0.20.3-0.50.30.2-0.4-0.7
Delay disc. indifference point, 2s delay0.40.51.0-0.40.40.70.60.5-1.00.6-0.8-0.80.9-0.7
Delay disc. indifference point, 24s delay0.50.91.51.0-1.1-1.0-0.6-1.10.7-1.20.90.8-1.1-0.3
Delay disc. indifference point, 4s delay0.80.81.31.1-1.1-1.0-0.9-1.00.8-0.90.90.7-0.80.5
Delay disc. indifference point, 8s delay0.60.91.51.2-1.2-1.1-0.8-1.10.7-1.10.90.8-0.90.5
Indifference point function ln k0.10.30.4-0.60.50.30.60.5-0.50.5-0.5-0.60.30.5
Indifference point function log k0.10.30.4-0.60.50.30.60.5-0.50.5-0.5-0.60.30.5
Patch foraging total patch changes 0 sec0.20.71.20.6-0.5-0.6-0.8-0.81.0-0.80.90.9-0.91.1
Patch foraging total patch changes 12 sec0.10.11.2-0.20.30.10.00.20.30.00.10.4-0.01.1
Patch foraging total patch changes 18 sec0.61.42.11.0-0.8-0.9-1.2-1.11.5-1.11.31.4-1.21.3
Patch foraging total patch changes 24 sec0.00.20.5-0.40.60.70.20.3-0.20.4-0.2-0.30.40.1
Patch foraging total patch changes 6 sec0.10.20.30.4-0.2-0.2-0.6-0.50.4-0.30.50.5-0.20.4
Patch foraging time to switch 0 sec0.51.83.11.5-1.3-1.1-1.8-1.71.0-1.01.30.8-1.11.7
Patch foraging water rate 0 sec0.10.42.5-0.50.50.40.60.6-0.10.2-0.3-0.10.1-1.6
Patch foraging water rate 12 sec0.00.10.5-0.70.60.30.40.5-0.20.2-0.2-0.10.2-0.3
Patch foraging water rate 18 sec0.20.43.8-0.10.30.60.20.3-0.20.2-0.1-0.20.3-2.0
Patch foraging water rate 24 sec0.20.31.3-0.70.80.50.40.70.20.2-0.10.20.1-1.2
Patch foraging water rate 6 sec0.20.42.1-0.70.60.40.50.6-0.20.3-0.3-0.20.2-1.4
Seeking ratio, delayed vs. immediate footshock0.30.41.10.5-0.5-0.7-0.8-0.41.0-0.50.70.8-0.7-0.6
Distance traveled before self-admin0.81.83.31.1-1.1-1.4-1.3-1.01.8-1.31.41.7-1.50.3
Distance traveled after self-admin0.61.01.91.0-0.9-1.0-1.1-0.71.4-0.91.11.2-1.1-0.0
Extensor digitorum longus weight0.20.81.6-0.70.70.81.01.1-0.70.8-1.0-0.70.9-1.3
Bone: elastic displacement0.10.20.6-0.40.50.40.70.3-0.10.0-0.1-0.10.10.8
Bone: elastic work0.00.00.20.00.10.20.2-0.00.1-0.20.10.0-0.10.4
Bone: endosteal estimation2.56.28.72.8-3.0-2.6-2.2-2.32.4-2.62.32.3-2.4-2.4
Bone: endosteal perimeter1.33.14.52.0-2.1-2.0-1.7-1.61.7-1.81.61.7-1.8-1.0
Epididymis fat weight1.15.427.41.5-1.0-1.2-2.6-2.41.7-1.52.21.7-1.55.2
Delta time in closed arm before/after self-admin1.31.21.81.1-1.1-1.2-1.0-1.31.1-1.31.21.1-1.40.5
Delta time in open arm before/after self-admin0.40.50.7-0.60.60.70.50.6-0.80.8-0.8-0.80.8-0.1
Diff in mean of infusions in LGA sessions0.10.30.6-0.20.50.70.20.5-0.50.6-0.4-0.30.6-0.8
Delay discount exponential model param0.20.30.5-0.70.70.60.40.6-0.40.7-0.5-0.50.50.4
Extinction: sum of active levers before priming0.10.10.4-0.40.40.20.20.3-0.20.3-0.3-0.20.30.6
Active lever presses in extinction session 60.10.10.5-0.00.00.40.2-0.1-0.50.2-0.2-0.70.2-0.3
Bone: final force3.35.36.52.4-2.3-2.3-2.4-2.62.3-2.42.52.2-2.41.3
Bone: final moment2.43.94.82.1-2.0-2.0-2.1-2.22.0-2.12.21.8-2.11.0
Food consumed during 24 hour testing period0.61.22.51.6-1.4-0.9-1.5-1.20.8-0.81.00.7-0.8-1.1
Glucose0.40.61.4-0.70.40.41.20.9-0.70.6-0.9-0.60.7-0.8
Heart weight2.13.45.1-2.01.82.02.31.9-1.91.7-1.9-1.81.9-0.8
Delay discount hyperbolic model param0.10.10.2-0.50.50.40.20.4-0.20.4-0.2-0.20.20.3
Intermittent access intake day 1-15 change0.31.41.91.4-1.2-1.3-1.4-1.31.2-1.21.21.1-1.20.4
Intermittent access intake escalation0.31.52.21.4-1.2-1.3-1.5-1.41.2-1.21.21.0-1.20.5
Intermittent access intake escalation 20.10.20.40.6-0.6-0.6-0.5-0.60.3-0.50.40.2-0.4-0.5
Intermitt. access day 1 inactive lever presses0.10.91.7-1.21.20.80.81.3-0.51.0-0.9-0.40.9-1.0
Intermitt. access day 15 inactive lever presses0.10.81.30.7-0.9-1.1-0.7-0.71.1-1.00.91.1-1.0-0.3
Intermitt. access escalation Index0.10.40.8-0.70.90.60.40.8-0.40.8-0.7-0.40.70.3
Intermittent access day 1 total infusions0.72.13.7-1.71.41.41.91.3-1.71.2-1.5-1.51.20.8
Intermittent access day 15 total infusions0.10.11.1-0.20.10.00.3-0.1-0.3-0.0-0.1-0.30.01.1
Intermittent access terminal intake (last 3 days)0.10.22.1-0.20.1-0.00.3-0.1-0.3-0.1-0.1-0.3-0.01.4
Intermittent access total infusions0.40.40.8-0.80.60.50.90.5-0.80.5-0.6-0.80.50.7
Intermittent access day 1 locomotion0.00.10.20.0-0.2-0.20.1-0.10.2-0.30.20.4-0.30.2
Intermittent access day 15 total locomotion1.45.66.82.4-2.6-2.5-2.2-2.42.5-2.62.52.6-2.60.3
Intermittent access total locomotion0.91.11.41.0-1.2-1.1-0.8-1.01.1-1.21.11.2-1.1-0.1
Intermittent access standard deviation0.42.12.81.6-1.5-1.5-1.7-1.61.5-1.51.61.4-1.5-0.2
Left kidney weight1.612.715.73.6-3.7-4.0-3.2-3.63.8-3.93.73.8-3.81.1
Right kidney weight2.819.424.94.6-4.8-5.0-4.3-4.74.3-4.84.44.5-4.61.2
Cocaine induced anxiety0.00.00.3-0.1-0.0-0.1-0.00.2-0.10.1-0.2-0.10.1-0.6
Post-drug Anxiety0.10.10.40.2-0.10.1-0.20.0-0.20.2-0.1-0.20.2-0.6
Baseline Anxiety0.00.10.20.5-0.10.2-0.4-0.30.1-0.00.30.1-0.10.5
Tail length0.84.56.02.0-2.3-2.5-1.3-1.62.2-2.31.92.2-2.3-2.3
Length with tail2.19.512.83.2-3.6-3.5-2.1-2.63.1-3.42.93.1-3.4-2.6
Length without tail1.58.111.13.2-3.3-3.1-2.4-2.82.8-3.22.82.8-3.1-0.7
Times rat made contact with spout1.82.13.1-1.41.61.81.21.4-1.51.6-1.4-1.51.70.2
Lifetime Intake0.10.20.6-0.40.20.20.60.2-0.60.2-0.4-0.50.20.7
Liver weight, left1.72.93.91.9-2.0-1.8-1.6-1.51.7-1.71.61.7-1.6-1.6
Liver weight, right3.15.47.02.2-2.4-2.5-1.7-1.62.6-2.42.22.6-2.4-2.6
Locomotor activity0.30.41.00.3-0.3-0.7-0.5-0.21.0-0.60.71.0-0.80.2
Locomotor testing distance0.10.20.70.1-0.0-0.2-0.5-0.10.5-0.20.40.5-0.40.8
Locomotor testing rearing0.51.82.41.4-1.3-1.4-1.5-1.31.5-1.41.41.5-1.40.5
Locomotion in novel chamber0.60.81.4-1.01.01.01.01.0-0.60.7-0.7-0.40.91.2
Locomotion in novel chamber post-restriction0.82.53.01.7-1.6-1.5-1.7-1.71.6-1.71.71.6-1.41.1
Fecal boli incidents, locomotor time 10.00.10.40.3-0.30.1-0.1-0.2-0.50.0-0.1-0.30.2-0.6
Change in fecal boli incidents, locomotor task1.01.06.50.6-0.5-0.6-0.7-0.60.9-0.50.71.1-0.62.6
Time >=10cm from walls, locomotor time 12.32.84.62.1-1.7-1.6-2.1-1.71.7-1.51.71.8-1.5-0.1
Bouts of movement, locomotor time 10.00.00.2-0.10.20.1-0.00.30.10.2-0.10.20.2-0.4
Total resting periods, locomotor time 10.10.10.50.1-0.2-0.1-0.20.00.3-0.00.10.4-0.0-0.7
Rest time, locomotor task time 10.00.10.3-0.3-0.1-0.20.30.1-0.3-0.2-0.20.1-0.0-0.5
Distance moved, locomotor task time 10.20.72.80.8-0.6-0.5-0.8-0.61.0-0.50.80.5-0.71.7
Vertical activity count, locomotor time 10.31.73.91.7-1.3-0.9-1.6-1.31.2-0.91.30.9-1.02.0
Time >=10cm from walls, locomotor time 21.23.56.02.4-2.3-1.9-2.2-2.41.1-1.81.71.2-1.61.4
Bouts of movement, locomotor time 20.20.61.70.8-0.7-0.6-0.7-0.40.9-0.60.70.9-0.6-1.3
Total resting periods, locomotor time 20.00.21.30.2-0.2-0.2-0.20.10.5-0.20.20.4-0.1-1.1
Rest time, locomotor task time 20.10.20.9-0.20.0-0.2-0.00.20.4-0.20.10.7-0.1-0.9
Distance moved, locomotor task time 21.92.53.71.9-1.8-1.4-1.6-1.91.2-1.51.60.9-1.51.9
Vertical activity count, locomotor time 20.51.32.51.6-1.5-1.0-1.2-1.50.6-1.01.00.3-1.00.9
Light reinforcement 10.93.95.42.0-1.9-2.0-2.3-2.02.1-1.92.12.2-2.00.6
Light reinforcement 21.63.54.92.2-2.1-1.9-2.2-2.01.7-1.81.91.8-1.8-1.2
Bone: marrow area2.76.59.22.9-3.0-2.7-2.3-2.42.4-2.62.42.4-2.5-2.4
Bone: maximum diameter0.10.21.40.3-0.6-0.60.1-0.10.2-0.40.10.2-0.3-1.2
Bone: maximum force0.71.41.91.1-1.2-1.2-1.1-1.31.2-1.41.31.0-1.40.1
Bone: maximum moment0.40.71.10.8-0.9-0.9-0.7-1.00.8-1.00.90.7-1.0-0.3
Mean time between licks in bursts0.21.12.2-1.10.80.71.31.5-0.81.0-1.2-0.80.9-1.1
Mean num. licks in bursts0.10.30.6-0.20.40.70.20.2-0.70.6-0.5-0.60.8-0.1
Cd content in liver0.20.20.80.5-0.30.2-0.2-0.4-0.50.0-0.0-0.50.1-0.9
Co content in liver1.92.33.41.8-1.5-1.3-1.7-1.81.1-1.41.51.1-1.41.8
Cu content in liver2.63.03.7-1.91.91.91.31.5-1.91.9-1.7-1.91.71.3
Fe content in liver1.72.12.71.4-1.5-1.7-1.3-1.51.5-1.61.51.6-1.60.7
K content in liver0.80.81.3-1.10.90.81.21.1-0.50.8-0.8-0.50.90.6
Mg content in liver0.80.91.7-1.00.90.91.11.3-0.81.0-1.1-0.81.1-0.1
Mn content in liver0.20.21.50.2-0.3-0.40.30.40.4-0.2-0.00.5-0.2-1.2
Na content in liver0.30.32.4-0.30.3-0.10.10.20.6-0.20.30.6-0.11.6
Rb content in liver0.00.10.10.3-0.10.3-0.0-0.0-0.30.2-0.1-0.30.20.4
Se content in liver1.61.93.4-1.51.31.21.91.8-1.01.2-1.4-0.91.3-1.2
Sr content in liver0.20.21.90.1-0.00.30.1-0.0-0.30.1-0.1-0.30.2-1.4
Zn content in liver1.21.41.7-1.11.01.21.31.2-1.31.2-1.3-1.31.1-0.9
Bone: minimum diameter0.61.21.91.3-1.4-1.2-0.9-1.01.0-1.11.01.0-1.2-0.7
Time in familiar zone, hab. session 10.10.10.4-0.30.30.30.30.1-0.40.3-0.3-0.50.20.6
Time in novel zone, hab. session 10.20.30.60.5-0.6-0.6-0.4-0.40.6-0.50.50.8-0.50.1
Total zone transitions, hab. session 12.53.55.9-2.42.31.81.92.0-1.61.8-1.8-1.81.90.7
Total locomotion distance, hab. session 11.82.54.3-2.11.91.51.81.8-1.31.5-1.5-1.51.50.7
Locomotion velocity, hab. session 11.82.54.5-2.11.91.51.81.8-1.31.4-1.5-1.51.50.5
Time in familiar zone, hab. session 20.60.71.2-0.90.90.90.41.0-0.71.1-0.8-0.80.8-0.9
Time in novel zone, hab. session 20.80.91.31.1-1.1-0.8-0.6-1.10.7-1.10.90.9-0.80.9
Total zone transitions, hab. session 20.20.30.9-1.00.90.40.50.7-0.00.3-0.3-0.20.4-0.1
Total locomotion distance, hab. session 21.52.04.0-2.01.91.41.41.8-0.91.4-1.3-1.11.3-0.4
Locomotion velocity, hab. session 22.02.65.2-2.32.21.61.72.0-1.11.5-1.5-1.31.5-0.6
Novel to familiar place preference ratio0.10.21.10.0-0.1-0.3-0.0-0.30.3-0.40.30.3-0.21.1
Novelty place preference0.10.10.80.0-0.1-0.30.0-0.30.2-0.40.30.3-0.20.9
Time in novel zone, NPP test0.10.20.70.2-0.3-0.3-0.1-0.40.3-0.50.30.4-0.30.8
Total zone transitions, NPP test1.62.33.9-2.01.81.51.71.7-1.41.4-1.6-1.31.6-0.2
Total locomotion distance, NPP test1.31.82.6-1.61.61.51.41.4-1.41.3-1.3-1.31.4-0.3
Locomotion velocity, NPP test1.82.63.9-2.01.91.71.61.7-1.61.6-1.6-1.51.7-0.3
Intraocular pressure0.81.21.71.0-1.1-1.2-0.9-1.01.2-1.31.11.3-1.20.9
Delta distance traveled before/after self-admin0.40.51.0-0.30.40.70.40.4-0.90.7-0.7-1.00.7-0.8
Delta ambulatory time before/after self-admin0.10.20.7-0.10.20.50.20.3-0.80.5-0.5-0.80.6-0.2
Parametrial fat weight4.811.313.43.5-3.3-3.4-3.7-3.43.6-3.43.63.7-3.41.7
Pavlov. Cond. lever latency1.21.63.91.7-1.3-0.9-2.0-1.51.1-0.91.31.1-0.9-0.3
Pavlov. Cond. magazine entry latency1.11.42.7-1.31.10.91.71.4-1.01.0-1.2-1.10.9-0.9
Pavlov. Cond. change in total contacts0.30.31.90.1-0.3-0.60.2-0.20.4-0.60.30.4-0.61.4
Pavlov. Cond. index score0.91.13.1-1.41.00.71.81.3-0.90.7-1.1-0.90.7-0.3
Pavlov. Cond. latency score0.70.92.7-1.30.90.61.71.2-0.80.6-1.0-0.80.6-0.2
Pavlov. Cond. lever contacts0.60.72.3-1.20.80.61.51.0-0.70.5-0.9-0.70.50.3
Pavlov. Cond. magazine entry number1.51.93.21.6-1.4-1.2-1.8-1.61.2-1.21.41.3-1.30.5
Pavlov. Cond. intertrial magazine entries0.10.10.20.3-0.20.2-0.2-0.4-0.40.00.1-0.40.00.2
Pavlov. Cond. lever-magazine prob. diff.0.81.03.1-1.41.00.71.81.3-0.80.6-1.0-0.90.70.0
Pavlov. Cond. response bias1.51.83.9-1.71.31.12.01.7-1.21.1-1.4-1.21.1-0.3
Pavlov. Cond. lever latency1.92.63.61.6-1.7-1.9-1.7-1.71.7-1.71.71.5-1.7-0.2
Pavlov. Cond. magazine entry latency0.20.31.30.7-0.7-0.3-0.3-0.40.2-0.40.30.3-0.3-1.1
Pavlov. Cond. change in total contacts0.51.21.8-0.91.01.31.11.1-1.21.2-1.1-1.11.2-0.2
Pavlov. Cond. index score0.30.50.7-0.50.60.80.80.7-0.80.7-0.7-0.60.7-0.4
Pavlov. Cond. latency score0.20.30.4-0.40.40.70.70.6-0.60.6-0.6-0.40.6-0.3
Pavlov. Cond. lever contacts1.42.13.0-1.41.51.71.51.5-1.61.5-1.5-1.41.50.4
Pavlov. Cond. magazine entry number0.10.10.3-0.50.40.10.20.3-0.10.2-0.2-0.20.10.3
Pavlov. Cond. intertrial magazine entries0.10.30.7-0.60.50.40.40.8-0.40.7-0.7-0.30.60.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.5-0.40.40.70.70.6-0.70.6-0.6-0.50.6-0.4
Pavlov. Cond. response bias0.91.21.7-0.91.01.31.31.1-1.31.1-1.1-1.11.1-0.1
Time in closed arm before self-admin0.20.40.6-0.40.50.80.60.6-0.60.6-0.5-0.60.6-0.7
Time in closed arm after self-admin0.20.20.8-0.40.50.50.60.3-0.50.3-0.3-0.40.20.9
Time in open arm before self-admin0.20.20.4-0.70.50.30.60.5-0.50.4-0.5-0.50.40.0
Time in open arm after self-admin0.60.71.4-0.70.60.60.60.7-0.80.8-0.9-0.90.9-1.2
Bone: periosteal estimation1.02.43.41.7-1.9-1.8-1.3-1.51.5-1.71.51.4-1.6-1.3
Bone: periosteal perimeter0.30.70.90.9-1.0-1.0-0.8-0.70.8-0.80.80.8-0.9-0.0
Bone: post-yield work0.20.32.40.4-0.6-0.4-0.0-0.40.1-0.40.2-0.0-0.4-1.5
Progressive ratio test 1 active lever presses0.00.10.1-0.30.20.30.40.2-0.40.2-0.2-0.30.20.3
Progressive ratio test 1 breakpoint0.10.20.3-0.50.30.50.50.3-0.50.3-0.3-0.40.40.3
Progressive ratio test 1 inactive lever presses0.30.92.30.7-0.7-0.9-0.9-0.91.0-0.91.01.0-0.91.5
Progressive ratio test 2 active lever presses0.10.10.7-0.30.20.10.20.1-0.20.1-0.1-0.20.00.8
Progressive ratio test 2 breakpoint0.10.10.7-0.40.30.20.30.1-0.30.2-0.2-0.20.10.9
Progressive ratio test 2 inactive lever presses0.00.10.5-0.50.30.20.50.3-0.20.1-0.2-0.10.10.7
Incentive Sensitization - Responses0.30.71.3-1.11.10.80.91.0-0.60.8-0.8-0.60.70.4
Incentive Sensitization - Breakpoint0.20.40.8-0.90.80.50.60.7-0.40.6-0.5-0.40.50.6
Sum of active levers in priming session hrs 5-60.20.20.5-0.40.30.30.50.3-0.60.3-0.5-0.70.4-0.1
Progressive ratio1.85.46.92.5-2.3-2.4-2.6-2.42.5-2.32.52.4-2.40.9
Food seeking constrained by brief footshock0.30.43.2-0.20.30.60.30.2-0.50.4-0.3-0.70.3-1.8
Seeking ratio, punishment vs. effort1.94.15.1-2.12.02.12.22.0-2.22.0-2.1-2.31.9-1.4
Retroperitoneal fat weight1.14.76.52.0-2.0-2.2-2.0-2.02.6-2.32.42.5-2.21.4
Reaction time number correct0.31.12.01.1-1.0-1.0-1.4-1.31.0-1.01.21.0-1.00.2
Reaction time mean minus median0.10.41.40.5-0.7-0.7-0.1-0.20.4-0.60.30.6-0.4-1.2
Reaction time mean minus median AUC0.00.31.80.5-0.7-0.40.1-0.10.2-0.40.20.4-0.3-1.4
Reaction time num false alarms0.10.10.3-0.30.3-0.00.30.60.5-0.00.00.50.0-0.5
Reaction time num false alarms AUC0.20.51.4-0.90.80.60.91.20.00.5-0.50.00.6-0.8
Reaction time trials correct on left0.31.12.01.1-1.0-1.0-1.4-1.31.0-1.01.21.0-1.00.2
Reaction time trials on left0.31.11.91.1-1.0-1.0-1.4-1.21.0-1.01.21.1-1.00.1
Reaction time mean0.10.20.70.6-0.7-0.4-0.1-0.30.0-0.30.10.1-0.1-0.8
Reaction time mean AUC0.20.41.11.0-1.0-0.7-0.4-0.60.3-0.60.40.4-0.4-0.8
Median of all reaction times0.10.10.40.6-0.6-0.3-0.2-0.4-0.0-0.20.1-0.0-0.1-0.3
Reaction time omissions0.30.51.00.8-0.7-0.7-0.6-0.30.8-0.60.61.0-0.5-0.5
Reaction time false alarm rate1.11.53.2-1.51.41.11.71.8-0.71.1-1.2-0.71.1-0.8
Reaction time premature initiation rate0.10.10.8-0.20.30.30.20.3-0.30.4-0.3-0.20.30.9
Reaction time premature initiations0.10.31.10.6-0.4-0.3-0.7-0.60.4-0.30.50.5-0.41.1
Std. dev. reaction times0.10.32.80.3-0.5-0.30.30.1-0.1-0.1-0.20.10.0-1.7
Reaction time trials completed0.31.11.91.1-1.0-1.0-1.4-1.21.0-1.01.21.1-1.00.1
Reaction time trials AUC0.31.12.01.2-1.0-1.0-1.4-1.31.0-1.01.21.1-1.00.1
Run reversals in cocaine runway, females0.20.21.3-0.2-0.00.20.3-0.1-0.60.1-0.2-0.50.31.1
Run reversals in cocaine runway, males0.30.41.10.4-0.7-0.9-0.0-0.30.5-0.60.30.5-0.6-1.0
Latency to leave start box in cocaine runway0.71.01.2-0.91.11.11.01.0-1.11.1-1.1-1.11.0-0.3
Latency to leave start box in cocaine runway, F0.70.91.2-0.91.01.00.90.9-1.11.0-1.0-1.10.9-0.6
Latency to leave start box in cocaine runway, M0.10.10.6-0.10.20.10.10.1-0.10.1-0.10.00.10.8
Std. dev. time between licks in bursts0.10.20.4-0.3-0.0-0.50.50.50.5-0.30.00.7-0.4-0.4
Total sessions with >9 infusions0.20.20.4-0.60.40.40.60.4-0.50.4-0.5-0.50.4-0.0
Short access day 1 total inactive lever presses0.00.00.10.0-0.3-0.30.3-0.1-0.2-0.3-0.1-0.2-0.1-0.3
Short access day 10 total inactive lever presses0.00.20.7-0.10.3-0.2-0.40.30.8-0.00.30.8-0.2-0.1
Short access day 1 total infusions0.40.71.2-1.00.80.81.10.9-1.00.8-0.9-0.90.80.2
Short access day 10 total infusions0.00.10.1-0.30.30.30.30.3-0.20.2-0.2-0.10.2-0.1
Short access total infusions0.10.20.4-0.50.30.30.60.3-0.60.3-0.4-0.50.30.6
Short access day 1 locomotion0.10.20.4-0.70.50.30.40.6-0.10.4-0.30.10.3-0.4
Short access day 10 total locomotion0.10.32.7-0.20.20.10.00.50.50.10.10.6-0.1-1.6
Short access total locomotion0.20.22.2-0.0-0.00.0-0.10.20.3-0.00.10.5-0.1-1.5
One hour access (0.3 mA shock)2.53.04.0-2.01.91.61.81.8-1.81.8-1.9-1.91.7-0.2
Compulsive drug intake1.82.73.3-1.41.51.51.31.6-1.71.7-1.8-1.81.8-1.8
One hour access (shock baseline)0.00.10.6-0.30.20.20.50.2-0.20.0-0.1-0.10.00.8
Social response proportion0.10.20.4-0.20.10.20.30.2-0.60.4-0.5-0.50.4-0.6
Social responses0.00.00.1-0.10.20.10.00.30.10.2-0.10.00.1-0.4
Social time0.10.21.4-0.20.1-0.20.10.60.30.1-0.10.30.1-1.2
Soleus weight0.41.15.80.7-1.0-1.10.1-0.11.0-1.00.51.0-0.9-2.4
Bone: stiffness0.50.91.50.9-1.0-1.1-1.1-1.20.8-1.01.00.7-1.00.4
Tibialis anterior weight0.41.52.0-1.11.31.41.01.2-1.31.4-1.3-1.31.40.1
Time to tail flick, vehicle, before self-admin3.74.66.62.0-1.8-2.3-2.1-1.72.5-2.02.12.6-2.12.1
Time to tail flick, vehicle, after self-admin0.30.61.0-0.70.70.90.60.7-1.00.9-0.9-0.81.0-0.3
Time to tail flick, test, before self-admin0.10.10.4-0.50.60.20.10.50.60.10.10.5-0.20.2
Time to tail flick, test, after self-admin0.10.11.2-0.10.0-0.10.10.10.0-0.1-0.10.0-0.11.1
Delta time to tail flick, vehicle, before/after SA4.44.77.4-2.01.92.42.01.7-2.72.2-2.2-2.72.3-1.3
Delta time to tail flick, test, before/after SA0.40.52.10.8-0.9-0.7-0.7-0.90.1-0.60.40.1-0.31.4
Tibia length2.57.09.23.0-3.0-3.0-2.5-2.62.6-2.82.62.6-2.7-0.9
Ambulatory time before self-admin0.20.61.60.5-0.5-0.7-0.6-0.41.3-0.70.91.2-0.9-0.4
Ambulatory time after self-admin0.20.30.60.5-0.4-0.4-0.6-0.20.8-0.40.60.7-0.5-0.7
Bone: tissue strength0.10.10.30.2-0.10.0-0.2-0.20.1-0.20.30.1-0.3-0.6
Total heroin consumption0.10.10.6-0.20.40.40.10.5-0.10.5-0.3-0.00.3-0.8
Bone: trabecular number0.81.52.9-1.11.01.21.00.9-1.71.4-1.4-1.71.4-0.3
Bone: trabecular spacing1.62.33.01.6-1.6-1.6-1.5-1.41.7-1.61.61.7-1.70.1
Bone: trabecular thickness0.20.30.50.7-0.7-0.6-0.4-0.70.4-0.70.60.4-0.6-0.2
Bone: trabecular tissue density0.10.10.6-0.0-0.1-0.20.30.10.2-0.30.20.2-0.4-0.8
Water consumed over 24 hours0.40.81.3-0.70.91.10.60.9-0.91.1-0.9-1.11.1-0.5
Number of responses in last shaping day1.72.23.5-1.81.41.31.91.4-1.81.3-1.7-1.71.5-0.1