Hub : Genes

Lamb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Lamb3 0.06 0.04 1.3e-04 0.01 0.01 0.01 0.01 5.6e-02 2.5e-02 2.2e-02 4.3e-02
2 pVTA gene expression Lamb3 0.12 0.07 9.3e-07 0.09 0.07 0.08 0.09 2.0e-07 3.3e-06 4.8e-07 1.5e-07
3 NAcc gene expression Lamb3 0.04 0.03 3.6e-05 0.04 0.03 0.02 0.03 3.5e-06 1.7e-05 1.5e-04 1.7e-05
4 IL gene expression Lamb3 0.38 0.18 1.6e-03 0.1 0.06 0.04 0.08 2.2e-03 1.4e-02 3.1e-02 4.9e-03
5 Adipose gene expression Lamb3 0.17 0.08 0.0e+00 0.13 0.17 0.16 0.16 5.2e-14 4.5e-18 2.0e-17 2.9e-17
6 LHb gene expression Lamb3 0.2 0.12 4.4e-03 0.05 0.1 0.04 0.09 2.2e-02 3.0e-03 4.1e-02 4.8e-03
7 IC gene expression Lamb3 0.22 0.1 9.7e-09 0.19 0.16 0.18 0.19 2.4e-08 3.9e-07 3.5e-08 2.4e-08
8 OFC gene expression Lamb3 0.19 0.13 2.8e-03 0.1 0.08 0.06 0.07 2.9e-03 7.0e-03 1.9e-02 8.5e-03
9 PL gene expression Lamb3 0.1 0.06 5.8e-13 0.13 0.12 0.12 0.12 7.4e-14 3.2e-13 6.4e-13 3.6e-13
10 Eye gene expression Lamb3 0.39 0.17 2.8e-04 0.14 0.13 0.18 0.19 3.3e-03 4.7e-03 1.1e-03 7.3e-04
11 BLA gene expression Lamb3 0.06 0.04 8.2e-03 0.01 0.01 -0 0 1.4e-01 1.2e-01 3.9e-01 1.8e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.00.10.3-0.5-0.00.3-0.10.2-0.50.10.00.10.0-0.3
Area under the delay curve0.10.10.5-0.7-0.40.7-0.10.20.20.40.20.4-0.00.2
BMI with tail0.10.20.4-0.50.20.10.10.6-0.10.40.50.5-0.60.3
BMI without tail0.72.35.3-1.21.30.21.22.2-0.61.61.71.7-2.31.2
Body weight2.310.219.6-0.94.0-0.84.34.4-2.03.03.23.2-4.41.8
Weight adjusted by age0.81.33.3-0.11.7-0.51.81.4-1.30.90.80.9-1.30.1
Bone surface0.20.41.40.61.1-0.80.90.5-1.2-0.1-0.1-0.1-0.2-0.5
Bone volume0.10.20.5-0.50.50.20.60.7-0.50.50.40.5-0.50.1
Breakpoint value in progressive ratio session0.91.12.80.61.4-1.01.71.6-0.90.90.80.9-0.10.6
Number of licking bursts0.30.51.60.80.6-0.90.1-0.1-1.2-0.6-0.7-0.60.4-1.1
Context. condit. distance diff. score0.20.21.30.10.6-0.50.30.5-1.10.00.10.0-0.2-0.5
Locomotion velocity, session 11.81.95.02.11.8-2.21.30.2-1.7-0.9-0.8-0.9-0.1-1.0
Locomotion distance, session 11.01.23.60.91.7-1.41.31.1-1.90.10.10.1-0.7-0.6
Locomotion velocity, session 20.10.20.50.30.5-0.50.40.5-0.70.10.10.1-0.4-0.1
Locomotion distance, session 20.10.20.40.30.6-0.40.50.6-0.40.30.30.3-0.50.1
Locomotion velocity, session 31.92.24.2-1.11.10.31.51.9-0.11.81.71.8-2.01.4
Locomotion distance, session 32.32.55.2-2.3-1.02.0-0.41.01.61.71.81.7-1.21.9
Stereotopy head waving bouts, day 33.23.78.93.02.2-2.91.5-0.5-2.2-1.6-1.7-1.60.5-1.9
Stereotopy head waving duration, day 34.04.810.33.22.2-3.11.5-0.7-2.6-1.9-2.1-1.90.8-2.4
Locomotion velocity, session 72.32.54.7-1.9-0.81.8-0.10.92.01.81.81.8-1.12.2
Locomotion distance, session 72.73.56.6-2.4-2.22.6-1.60.32.61.61.61.5-0.22.1
Stereotopy head waving bouts, day 72.73.07.12.32.7-2.52.30.4-2.3-0.7-0.8-0.8-0.4-1.4
Stereotopy head waving duration, day 73.44.08.22.72.7-2.92.0-0.1-2.8-1.4-1.4-1.40.1-2.1
Locomotion velocity, session 81.51.83.31.70.9-1.80.0-0.6-1.7-1.4-1.3-1.40.8-1.7
Locomotion distance, session 80.40.62.50.61.2-1.00.70.8-1.6-0.00.1-0.0-0.4-0.6
Degree of sensitization distance0.60.61.40.5-0.8-0.1-1.1-0.90.2-0.7-0.8-0.71.2-0.5
Degree of sensitization stereotypy0.50.61.50.91.2-1.01.10.2-1.0-0.3-0.2-0.3-0.2-0.6
Conditioned locomotion1.01.11.91.1-0.5-0.6-0.9-1.3-0.2-1.2-1.4-1.21.4-1.1
Cocaine response after cond. corrected0.70.81.51.20.3-0.9-0.1-0.8-0.7-1.2-1.1-1.20.8-1.1
Cocaine response after cond. not corrected1.61.93.21.80.7-1.60.0-0.9-1.5-1.7-1.5-1.71.0-1.8
Cocaine response before conditioning0.20.21.10.40.5-0.70.20.2-1.1-0.2-0.1-0.20.1-0.7
Saline control response0.91.13.4-1.8-1.41.5-1.40.40.60.90.90.9-0.00.6
Bone: connectivity density0.50.72.90.80.8-1.00.30.1-1.7-0.6-0.6-0.60.4-1.3
Bone: cortical apparent density0.10.10.4-0.3-0.40.3-0.4-0.00.70.20.10.2-0.20.5
Bone: cortical area0.81.22.7-0.51.2-0.11.31.6-0.81.21.21.2-1.40.6
Bone: cortical porosity0.80.91.80.9-0.1-0.7-0.4-0.9-0.8-1.1-1.2-1.10.9-1.4
Bone: cortical porosity0.60.71.40.6-0.3-0.4-0.6-0.9-0.6-1.0-1.1-1.01.0-1.2
Bone: cortical thickness0.30.51.30.61.1-0.90.90.6-1.2-0.00.0-0.0-0.4-0.4
Bone: cortical thickness0.81.03.00.71.5-1.31.21.0-1.70.10.20.1-0.6-0.5
Bone: cortical tissue density0.10.10.5-0.3-0.40.4-0.4-0.10.70.20.10.2-0.20.5
Condit. Reinf. active minus inactive responses1.01.11.9-1.4-0.41.20.10.90.81.31.31.3-0.81.3
Condit. Reinf. active-inactive response ratio0.30.41.0-0.7-1.00.9-0.8-0.30.70.20.20.20.40.3
Condit. Reinf. active responses2.43.05.0-2.0-0.01.50.61.90.82.22.22.2-1.72.0
Condit. Reinf. inactive responses1.31.63.1-1.20.80.51.11.8-0.21.61.61.6-1.61.1
Incentive salience index mean2.12.64.3-2.1-0.41.70.21.61.02.02.02.0-1.41.9
Condit. Reinf. lever presses2.53.66.0-2.3-0.01.60.62.20.72.42.42.4-2.02.1
Condit. Reinf. active minus inactive responses0.70.92.3-1.3-1.51.4-1.3-0.21.10.40.40.40.30.5
Condit. Reinf. active-inactive response ratio0.50.61.60.0-1.20.4-1.3-1.00.7-0.6-0.6-0.60.9-0.2
Condit. Reinf. active responses1.11.53.7-1.9-1.21.8-0.70.51.31.21.11.2-0.51.2
Condit. Reinf. inactive responses2.33.04.9-2.20.21.51.02.00.52.22.22.2-1.91.8
Condit. Reinf. lever presses1.11.53.6-1.9-0.51.50.01.00.91.41.41.4-1.11.3
Condit. Reinf. lever reinforcers received0.91.22.9-1.7-1.01.6-0.50.51.11.11.11.1-0.61.2
Conditioned reinforcement - actives0.30.51.50.71.0-1.00.80.5-1.2-0.1-0.2-0.00.2-0.6
Conditioned reinforcement - inactives1.01.54.21.12.1-1.51.81.3-1.80.30.20.5-0.7-0.3
Conditioned locomotion1.31.64.81.12.1-1.71.71.1-2.20.1-0.10.2-0.3-0.8
Patch foraging indifference point 0 sec0.40.83.10.61.2-1.01.00.5-1.7-0.3-0.1-0.2-0.1-1.0
Patch foraging indifference point AUC0.30.51.5-0.4-1.10.8-0.9-0.71.2-0.2-0.1-0.20.50.4
Delay disc. indifference point, 0s delay0.40.41.30.81.0-1.01.10.5-0.80.2-0.20.2-0.1-0.2
Delay disc. indifference point, 16s delay0.10.10.3-0.5-0.40.5-0.5-0.1-0.00.0-0.00.0-0.1-0.1
Delay disc. indifference point, 2s delay0.30.30.9-1.0-0.80.8-0.40.10.10.50.20.50.60.1
Delay disc. indifference point, 24s delay0.50.61.8-1.3-1.01.3-1.0-0.10.60.30.30.3-0.50.3
Delay disc. indifference point, 4s delay0.90.91.7-1.20.10.90.81.00.41.31.11.3-0.61.0
Delay disc. indifference point, 8s delay0.20.20.40.0-0.60.4-0.4-0.70.4-0.4-0.6-0.40.6-0.2
Indifference point function ln k1.32.25.12.01.8-2.11.40.0-2.3-1.0-1.0-1.00.3-1.6
Indifference point function log k1.32.25.12.01.8-2.11.40.0-2.3-1.0-1.0-1.00.3-1.6
Patch foraging total patch changes 0 sec0.40.73.00.51.1-1.00.90.6-1.7-0.2-0.1-0.2-0.1-0.9
Patch foraging total patch changes 12 sec0.20.30.7-0.00.8-0.40.70.9-0.80.30.60.3-0.60.1
Patch foraging total patch changes 18 sec0.20.30.6-0.30.6-0.00.70.7-0.10.60.70.6-0.70.5
Patch foraging total patch changes 24 sec0.40.61.5-1.2-0.20.90.00.80.40.81.00.9-0.70.9
Patch foraging total patch changes 6 sec0.30.41.0-1.00.10.70.50.70.10.61.00.6-0.60.6
Patch foraging time to switch 0 sec0.51.02.40.11.5-0.71.51.2-0.50.81.00.8-1.30.6
Patch foraging water rate 0 sec1.02.13.90.9-1.0-0.5-1.5-1.5-0.8-1.7-1.8-1.72.0-1.8
Patch foraging water rate 12 sec0.61.33.00.5-1.40.1-1.5-1.50.4-1.2-1.2-1.21.7-0.9
Patch foraging water rate 18 sec0.20.30.50.70.1-0.5-0.1-0.4-0.4-0.6-0.7-0.70.5-0.5
Patch foraging water rate 24 sec0.30.40.91.00.2-0.80.1-0.5-0.6-0.8-0.8-0.70.6-0.8
Patch foraging water rate 6 sec0.20.30.80.3-0.6-0.2-0.9-0.4-0.5-0.4-0.8-0.40.7-0.7
Seeking ratio, delayed vs. immediate footshock1.31.64.2-2.0-1.61.9-1.10.11.51.00.81.0-0.21.0
Distance traveled before self-admin1.21.65.61.21.8-1.71.10.6-2.4-0.3-0.5-0.3-0.3-1.4
Distance traveled after self-admin1.72.15.31.92.1-2.31.40.6-2.3-0.5-0.6-0.5-0.1-1.2
Extensor digitorum longus weight0.62.24.1-1.6-0.01.20.71.31.41.71.81.7-1.62.0
Bone: elastic displacement1.72.03.41.80.8-1.50.2-0.9-1.5-1.6-1.6-1.61.1-1.9
Bone: elastic work1.11.52.61.61.1-1.60.6-0.5-1.5-1.2-1.2-1.20.7-1.5
Bone: endosteal estimation0.20.40.7-0.50.30.40.60.70.20.70.90.7-0.60.7
Bone: endosteal perimeter0.81.83.2-1.50.11.10.61.50.61.71.81.7-1.41.5
Epididymis fat weight0.51.64.21.32.0-1.61.70.5-2.0-0.4-0.5-0.3-0.6-1.2
Delta time in closed arm before/after self-admin0.00.00.10.3-0.1-0.1-0.1-0.20.3-0.2-0.3-0.2-0.30.1
Delta time in open arm before/after self-admin2.62.65.2-2.3-0.51.70.11.51.02.12.12.1-0.71.8
Diff in mean of infusions in LGA sessions0.10.10.5-0.1-0.0-0.3-0.10.6-0.70.40.20.40.1-0.1
Delay discount exponential model param0.20.20.70.90.5-0.90.2-0.2-0.3-0.4-0.3-0.40.0-0.2
Extinction: sum of active levers before priming1.92.16.0-0.61.2-0.21.62.4-0.91.81.81.8-0.51.2
Active lever presses in extinction session 63.73.79.10.93.0-1.63.02.5-2.01.31.21.3-1.90.5
Bone: final force0.71.13.30.91.8-1.31.70.8-1.30.00.00.0-0.7-0.4
Bone: final moment0.60.93.00.51.7-0.91.71.0-1.10.40.40.4-0.9-0.0
Food consumed during 24 hour testing period0.60.91.81.21.3-1.31.20.3-1.3-0.4-0.5-0.4-0.2-0.7
Glucose0.50.91.61.0-0.2-0.6-0.5-1.0-0.5-1.1-1.0-1.11.3-1.1
Heart weight0.60.91.7-0.90.50.40.61.3-0.11.21.31.2-1.30.9
Delay discount hyperbolic model param0.30.31.01.00.5-0.90.1-0.3-0.2-0.6-0.4-0.60.1-0.3
Intermittent access intake day 1-15 change1.22.55.82.40.7-1.90.2-1.6-0.6-2.0-2.1-1.90.7-1.5
Intermittent access intake escalation1.53.26.62.60.6-2.0-0.1-1.8-0.7-2.3-2.3-2.21.0-1.8
Intermittent access intake escalation 22.02.35.02.20.7-1.80.1-1.4-0.7-1.9-1.9-1.80.9-1.5
Intermitt. access day 1 inactive lever presses0.10.30.7-0.00.6-0.20.60.60.10.60.50.6-0.80.5
Intermitt. access day 15 inactive lever presses0.40.92.8-0.60.70.40.70.90.41.11.11.0-1.71.0
Intermitt. access escalation Index0.30.41.0-0.8-0.60.8-0.50.21.00.60.60.5-0.60.9
Intermittent access day 1 total infusions0.61.02.1-0.01.4-0.41.41.4-1.10.80.90.9-1.10.3
Intermittent access day 15 total infusions2.03.07.02.61.6-2.40.9-0.9-1.8-1.9-1.8-1.70.6-1.9
Intermittent access terminal intake (last 3 days)1.31.85.02.21.7-2.11.2-0.3-1.2-1.1-1.1-1.00.2-1.0
Intermittent access total infusions0.91.12.51.61.3-1.60.8-0.1-1.4-0.8-0.8-0.70.3-1.1
Intermittent access day 1 locomotion1.31.74.40.52.1-1.02.01.6-1.60.80.70.8-1.3-0.1
Intermittent access day 15 total locomotion1.62.87.52.02.7-2.42.30.8-2.4-0.6-0.5-0.5-0.6-1.2
Intermittent access total locomotion1.11.33.80.82.0-1.31.61.0-1.90.20.10.3-0.9-0.6
Intermittent access standard deviation0.20.31.21.10.6-0.70.5-0.50.1-0.5-0.7-0.3-0.3-0.2
Left kidney weight1.15.012.50.33.5-1.33.52.9-2.11.61.61.7-2.90.6
Right kidney weight1.67.320.61.14.5-2.34.53.0-2.81.41.31.5-3.20.2
Cocaine induced anxiety1.42.03.7-1.20.50.81.01.70.81.91.81.9-1.31.9
Post-drug Anxiety0.20.20.40.20.5-0.20.50.50.30.50.40.5-0.60.7
Baseline Anxiety4.45.18.72.6-0.3-1.8-1.2-2.6-1.0-2.9-2.9-2.91.9-2.7
Tail length2.38.918.5-1.92.90.33.44.1-1.03.23.33.4-4.32.3
Length with tail3.515.029.1-1.04.9-0.95.45.3-2.33.83.93.9-5.22.3
Length without tail1.65.114.70.83.6-1.73.82.7-2.41.51.41.4-2.40.3
Times rat made contact with spout0.20.20.40.40.6-0.60.60.2-0.6-0.1-0.3-0.1-0.2-0.3
Lifetime Intake0.91.12.61.51.4-1.61.00.2-1.6-0.6-0.6-0.50.0-1.0
Liver weight, left0.30.51.60.41.3-0.71.20.8-0.90.30.30.3-0.8-0.1
Liver weight, right0.91.63.01.61.4-1.70.8-0.3-1.7-1.2-1.1-1.20.4-1.5
Locomotor activity1.01.63.81.92.0-1.81.60.2-1.3-0.5-0.7-0.6-0.6-0.8
Locomotor testing distance0.30.51.21.01.1-1.10.90.3-0.80.0-0.1-0.0-0.5-0.2
Locomotor testing rearing0.10.10.8-0.1-0.70.2-0.9-0.20.30.2-0.00.10.30.1
Locomotion in novel chamber0.10.20.6-0.5-0.40.6-0.0-0.20.80.10.30.1-0.00.4
Locomotion in novel chamber post-restriction0.10.20.7-0.2-0.70.4-0.8-0.30.30.0-0.10.00.6-0.1
Fecal boli incidents, locomotor time 10.00.10.10.1-0.30.1-0.4-0.30.2-0.1-0.2-0.10.3-0.0
Change in fecal boli incidents, locomotor task0.40.40.80.90.5-0.70.5-0.5-0.5-0.8-0.7-0.80.2-0.7
Time >=10cm from walls, locomotor time 10.30.30.90.80.5-1.00.20.1-0.7-0.3-0.4-0.30.2-0.4
Bouts of movement, locomotor time 11.01.12.21.2-0.0-0.8-0.3-1.1-0.6-1.3-1.5-1.31.2-1.2
Total resting periods, locomotor time 10.60.61.30.7-0.4-0.3-0.4-1.0-0.2-0.9-1.1-0.91.1-0.9
Rest time, locomotor task time 10.81.01.91.0-0.2-0.4-0.2-1.4-0.1-1.3-1.4-1.30.9-1.1
Distance moved, locomotor task time 10.71.02.20.51.5-1.21.51.4-1.00.70.70.7-0.90.3
Vertical activity count, locomotor time 10.10.10.50.30.2-0.6-0.20.2-0.7-0.2-0.2-0.2-0.0-0.4
Time >=10cm from walls, locomotor time 20.91.42.3-0.41.2-0.11.41.5-0.01.41.41.4-1.51.1
Bouts of movement, locomotor time 20.20.31.0-0.3-1.00.4-1.0-0.50.2-0.3-0.3-0.31.0-0.3
Total resting periods, locomotor time 20.10.20.5-0.2-0.70.3-0.6-0.30.0-0.2-0.2-0.20.7-0.2
Rest time, locomotor task time 20.60.81.41.1-0.4-0.5-0.7-1.20.3-1.1-1.1-1.10.8-0.6
Distance moved, locomotor task time 21.61.95.10.42.2-1.32.31.7-1.50.90.80.9-1.40.2
Vertical activity count, locomotor time 20.10.20.60.20.7-0.50.60.2-0.7-0.0-0.0-0.0-0.3-0.4
Light reinforcement 10.71.62.61.60.5-1.20.2-1.2-0.9-1.6-1.6-1.60.9-1.6
Light reinforcement 22.33.57.32.71.5-2.40.9-1.2-1.8-2.0-2.0-2.01.0-2.2
Bone: marrow area0.10.30.6-0.50.20.40.50.60.20.60.70.6-0.50.6
Bone: maximum diameter0.51.01.8-0.80.70.30.91.3-0.11.21.31.2-1.20.9
Bone: maximum force1.22.05.81.62.4-1.92.10.8-2.1-0.4-0.2-0.4-0.5-0.9
Bone: maximum moment1.01.85.31.22.3-1.62.11.1-1.80.00.20.0-0.8-0.6
Mean time between licks in bursts0.30.91.8-1.1-0.51.1-0.10.51.20.91.10.9-0.61.3
Mean num. licks in bursts0.30.41.0-0.6-0.20.70.10.31.00.70.70.7-0.61.0
Cd content in liver5.35.911.8-2.21.60.82.03.4-0.73.02.93.0-3.21.9
Co content in liver1.61.83.21.81.0-1.80.5-0.5-1.8-1.3-1.3-1.30.8-1.7
Cu content in liver1.72.04.30.2-1.90.7-1.9-2.11.6-1.3-1.3-1.31.7-0.3
Fe content in liver1.31.63.9-0.2-2.01.0-1.9-1.61.7-0.7-0.8-0.71.40.1
K content in liver0.40.30.70.3-0.70.0-0.8-0.80.6-0.6-0.6-0.60.6-0.1
Mg content in liver0.50.51.10.80.5-1.00.1-0.2-1.1-0.6-0.7-0.60.2-0.9
Mn content in liver0.20.30.7-0.8-0.60.5-0.70.40.10.50.40.5-0.20.4
Na content in liver1.01.12.20.2-1.40.5-1.4-1.51.2-0.9-0.9-0.91.3-0.2
Rb content in liver0.60.71.6-0.1-1.30.6-1.2-1.11.2-0.5-0.5-0.50.80.1
Se content in liver0.30.41.20.70.7-0.90.40.2-1.1-0.3-0.3-0.3-0.0-0.6
Sr content in liver2.32.04.4-2.1-1.22.0-0.50.61.61.41.41.4-0.81.6
Zn content in liver2.83.19.91.62.7-2.42.01.1-3.2-0.4-0.4-0.4-0.8-1.5
Bone: minimum diameter2.13.97.8-2.8-0.92.3-0.11.61.52.32.42.3-1.62.3
Time in familiar zone, hab. session 11.31.32.3-1.4-0.91.3-0.40.51.51.21.21.2-0.61.5
Time in novel zone, hab. session 11.01.02.90.71.7-1.11.51.0-1.30.20.20.2-1.0-0.2
Total zone transitions, hab. session 11.21.64.30.72.0-1.22.11.5-1.50.70.70.7-1.30.0
Total locomotion distance, hab. session 11.82.56.72.02.6-2.32.30.8-2.0-0.3-0.3-0.4-0.7-0.8
Locomotion velocity, hab. session 11.62.34.82.12.2-2.21.80.3-2.1-0.7-0.7-0.7-0.1-1.2
Time in familiar zone, hab. session 20.30.30.7-0.50.10.20.30.8-0.00.80.80.8-0.60.6
Time in novel zone, hab. session 20.20.20.5-0.40.40.10.50.50.10.50.50.5-0.70.4
Total zone transitions, hab. session 20.91.22.5-0.31.3-0.31.41.6-1.01.01.11.0-1.40.4
Total locomotion distance, hab. session 20.81.02.60.41.6-0.81.61.3-1.20.60.60.6-1.10.1
Locomotion velocity, hab. session 20.50.71.90.61.4-0.91.30.9-1.20.20.30.2-0.7-0.2
Novel to familiar place preference ratio0.00.00.10.10.1-0.2-0.1-0.2-0.2-0.2-0.2-0.20.1-0.3
Novelty place preference0.10.10.20.20.4-0.40.10.0-0.4-0.2-0.1-0.2-0.1-0.3
Time in novel zone, NPP test0.00.00.10.10.4-0.40.20.1-0.3-0.00.0-0.0-0.2-0.1
Total zone transitions, NPP test1.11.73.90.72.0-1.41.71.6-2.00.60.60.6-1.2-0.3
Total locomotion distance, NPP test0.71.02.30.51.5-1.01.41.3-1.40.50.60.5-1.0-0.1
Locomotion velocity, NPP test0.81.12.60.61.6-1.11.41.3-1.50.50.60.5-1.0-0.1
Intraocular pressure0.30.50.80.80.2-0.50.3-0.7-0.5-0.8-0.8-0.80.9-0.9
Delta distance traveled before/after self-admin0.10.10.40.10.2-0.10.40.30.40.30.40.3-0.10.6
Delta ambulatory time before/after self-admin0.10.10.30.2-0.4-0.0-0.3-0.30.3-0.2-0.1-0.20.60.1
Parametrial fat weight0.51.22.3-0.60.70.31.01.20.51.31.21.3-1.51.4
Pavlov. Cond. lever latency2.93.77.02.60.3-2.0-0.3-2.1-0.6-2.4-2.4-2.41.9-1.9
Pavlov. Cond. magazine entry latency4.65.99.5-2.80.22.11.22.71.13.13.03.1-2.72.8
Pavlov. Cond. change in total contacts4.24.49.0-3.0-0.62.30.02.20.92.62.62.6-2.02.2
Pavlov. Cond. index score3.94.99.2-3.0-0.82.50.12.11.42.72.72.7-1.92.5
Pavlov. Cond. latency score4.25.310.2-3.2-0.72.60.12.21.32.82.82.8-2.02.5
Pavlov. Cond. lever contacts1.92.24.2-2.0-0.31.60.21.60.61.91.81.9-1.41.5
Pavlov. Cond. magazine entry number4.45.58.82.7-0.0-2.1-1.0-2.5-1.2-2.9-2.9-3.02.6-2.8
Pavlov. Cond. intertrial magazine entries0.91.12.11.10.2-0.9-0.4-0.9-1.0-1.2-1.2-1.21.2-1.4
Pavlov. Cond. lever-magazine prob. diff.3.34.16.9-2.6-0.32.10.52.11.02.52.52.5-2.02.3
Pavlov. Cond. response bias3.74.57.2-2.30.31.71.12.50.82.72.72.7-2.52.4
Pavlov. Cond. lever latency0.81.11.81.3-0.2-0.8-0.6-1.4-0.0-1.3-1.3-1.31.2-1.0
Pavlov. Cond. magazine entry latency0.30.40.9-0.60.50.10.51.0-0.60.70.70.7-0.80.3
Pavlov. Cond. change in total contacts0.20.41.1-0.6-1.00.8-0.9-0.40.80.00.00.00.40.3
Pavlov. Cond. index score0.60.71.5-1.00.40.50.61.2-0.31.11.01.1-1.10.6
Pavlov. Cond. latency score0.60.81.4-1.20.20.60.41.1-0.21.11.01.1-1.10.7
Pavlov. Cond. lever contacts0.60.81.4-1.10.30.60.61.2-0.01.11.11.1-1.10.8
Pavlov. Cond. magazine entry number0.00.10.20.3-0.2-0.0-0.0-0.40.4-0.2-0.3-0.20.30.0
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.8-0.20.90.40.20.70.70.70.7-0.40.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.0-0.90.30.40.41.0-0.30.90.90.9-0.90.5
Pavlov. Cond. response bias0.81.12.3-1.00.60.40.91.5-0.31.31.31.3-1.30.9
Time in closed arm before self-admin0.10.10.30.1-0.00.0-0.3-0.5-0.1-0.4-0.4-0.4-0.1-0.5
Time in closed arm after self-admin1.31.43.61.90.8-1.50.2-1.1-0.7-1.3-1.5-1.40.1-1.3
Time in open arm before self-admin0.30.30.9-0.00.6-0.21.00.8-0.50.50.40.4-0.60.3
Time in open arm after self-admin2.83.05.6-2.4-0.51.80.41.71.12.22.22.2-0.92.1
Bone: periosteal estimation0.61.32.5-0.71.10.21.41.6-0.41.31.41.3-1.40.9
Bone: periosteal perimeter0.91.52.8-1.00.90.31.21.7-0.21.51.61.5-1.51.0
Bone: post-yield work0.20.30.50.70.3-0.60.0-0.4-0.5-0.7-0.5-0.70.6-0.7
Progressive ratio test 1 active lever presses0.81.02.0-0.21.1-0.21.41.3-0.41.01.01.1-1.20.7
Progressive ratio test 1 breakpoint0.70.92.1-0.01.2-0.31.41.3-0.50.90.91.0-1.10.6
Progressive ratio test 1 inactive lever presses1.31.93.0-0.81.10.41.51.70.21.71.61.7-1.71.4
Progressive ratio test 2 active lever presses0.20.30.80.30.8-0.40.90.7-0.30.40.30.50.00.3
Progressive ratio test 2 breakpoint0.20.20.80.40.8-0.50.90.6-0.40.30.20.40.10.2
Progressive ratio test 2 inactive lever presses1.11.85.31.02.3-1.42.21.4-1.70.50.40.5-0.9-0.2
Incentive Sensitization - Responses0.20.30.80.80.9-0.90.80.5-0.60.1-0.10.1-0.1-0.0
Incentive Sensitization - Breakpoint0.20.30.70.70.8-0.80.80.4-0.50.1-0.00.1-0.00.1
Sum of active levers in priming session hrs 5-62.62.45.9-0.12.1-0.72.42.3-1.41.31.61.3-1.20.7
Progressive ratio1.42.16.61.20.5-1.5-0.3-0.4-2.6-1.4-1.4-1.41.1-2.3
Food seeking constrained by brief footshock0.50.61.8-1.0-1.41.1-0.9-0.31.20.30.20.30.40.6
Seeking ratio, punishment vs. effort1.31.96.0-1.3-0.81.60.10.32.41.31.21.3-0.92.1
Retroperitoneal fat weight0.93.79.20.43.0-1.42.82.5-2.21.21.21.3-2.40.2
Reaction time number correct1.12.05.6-2.1-2.22.4-1.6-0.21.50.90.60.80.40.8
Reaction time mean minus median1.43.56.92.61.1-2.20.4-1.6-1.5-2.2-2.1-2.21.4-2.2
Reaction time mean minus median AUC0.92.34.72.20.6-1.60.2-1.6-0.7-1.9-1.8-1.81.4-1.6
Reaction time num false alarms1.72.46.0-0.5-2.51.3-2.1-2.01.9-0.9-0.8-0.91.8-0.1
Reaction time num false alarms AUC1.11.83.8-0.1-2.00.9-1.7-1.91.5-1.0-1.0-1.01.8-0.3
Reaction time trials correct on left1.12.05.6-2.1-2.22.4-1.6-0.21.50.90.60.80.40.8
Reaction time trials on left1.01.95.2-2.0-2.22.3-1.6-0.21.40.80.50.70.40.7
Reaction time mean1.72.86.62.61.5-2.20.8-1.1-1.4-1.8-1.7-1.70.9-1.8
Reaction time mean AUC1.93.06.72.61.1-2.10.4-1.5-1.3-2.0-2.0-2.01.3-2.0
Median of all reaction times1.01.43.71.91.2-1.60.7-0.8-0.9-1.2-1.2-1.10.5-1.1
Reaction time omissions1.92.85.71.70.5-1.5-0.3-1.4-1.7-2.1-1.8-2.11.7-2.4
Reaction time false alarm rate0.50.71.50.9-0.4-0.4-0.5-1.20.6-1.1-0.9-1.01.0-0.4
Reaction time premature initiation rate0.30.41.20.30.8-0.21.10.50.20.50.30.5-0.90.6
Reaction time premature initiations0.20.30.7-0.6-0.40.80.10.00.90.60.20.6-0.30.7
Std. dev. reaction times3.36.112.93.62.1-3.21.2-1.6-2.4-2.6-2.5-2.61.4-2.8
Reaction time trials completed1.01.95.2-2.0-2.22.3-1.6-0.21.40.80.50.70.40.7
Reaction time trials AUC1.22.36.3-2.3-2.32.5-1.7-0.21.60.90.60.90.40.8
Run reversals in cocaine runway, females0.10.10.20.40.3-0.40.40.10.30.10.10.1-0.10.3
Run reversals in cocaine runway, males0.50.51.41.20.5-0.80.3-0.7-0.2-0.8-0.8-0.80.4-0.6
Latency to leave start box in cocaine runway1.11.33.5-0.5-1.90.9-1.7-1.41.1-0.7-0.7-0.71.4-0.2
Latency to leave start box in cocaine runway, F0.80.92.20.4-1.1-0.1-1.2-1.20.1-1.0-1.0-1.01.5-0.9
Latency to leave start box in cocaine runway, M0.70.61.9-0.9-1.21.2-0.8-0.51.40.10.10.10.20.6
Std. dev. time between licks in bursts0.71.01.9-1.4-0.21.10.10.90.81.11.31.1-0.81.3
Total sessions with >9 infusions0.81.02.10.11.4-0.71.41.4-1.00.90.81.0-1.10.3
Short access day 1 total inactive lever presses0.81.13.20.91.8-1.31.71.0-1.10.50.30.4-1.0-0.0
Short access day 10 total inactive lever presses0.71.73.0-1.6-0.31.30.11.01.31.61.51.4-1.31.7
Short access day 1 total infusions0.40.61.1-0.00.9-0.41.01.0-0.70.80.60.8-1.10.2
Short access day 10 total infusions0.30.41.00.20.9-0.60.80.8-1.00.40.30.4-0.7-0.2
Short access total infusions0.70.92.30.71.5-1.21.20.8-1.50.20.10.2-0.8-0.5
Short access day 1 locomotion0.50.61.5-0.80.50.20.71.2-0.80.91.00.9-0.50.2
Short access day 10 total locomotion0.00.00.10.10.2-0.20.4-0.1-0.2-0.1-0.1-0.1-0.0-0.2
Short access total locomotion0.40.51.40.41.1-0.71.00.7-1.20.30.20.3-0.5-0.4
One hour access (0.3 mA shock)0.30.30.80.30.9-0.60.80.8-0.40.50.40.6-0.50.3
Compulsive drug intake1.82.13.8-2.0-1.11.9-0.50.61.91.51.41.4-0.91.9
One hour access (shock baseline)1.21.84.02.01.4-2.00.9-0.3-1.7-1.2-1.1-1.00.6-1.5
Social response proportion0.20.31.0-0.7-0.80.7-1.0-0.20.50.10.20.00.40.2
Social responses1.11.53.7-1.9-1.71.8-1.60.11.10.90.80.90.10.8
Social time0.20.30.9-0.7-0.90.7-1.0-0.20.40.10.10.10.20.1
Soleus weight1.95.59.71.8-1.0-1.1-1.8-2.7-1.1-2.9-2.8-2.93.1-2.9
Bone: stiffness0.81.33.70.61.9-1.11.81.2-1.20.50.60.5-1.10.0
Tibialis anterior weight0.82.64.2-1.80.11.20.81.61.22.02.02.0-1.82.0
Time to tail flick, vehicle, before self-admin0.40.51.10.80.1-0.6-0.2-0.7-0.2-1.0-0.9-1.00.2-0.6
Time to tail flick, vehicle, after self-admin0.50.72.10.61.4-0.91.20.9-1.10.30.30.3-0.7-0.2
Time to tail flick, test, before self-admin3.03.16.52.51.9-2.51.1-0.3-2.4-1.6-1.5-1.5-0.0-1.9
Time to tail flick, test, after self-admin1.81.95.31.62.3-1.72.10.6-1.8-0.5-0.4-0.4-1.1-0.9
Delta time to tail flick, vehicle, before/after SA0.50.51.10.11.0-0.51.11.0-0.80.70.60.7-0.50.1
Delta time to tail flick, test, before/after SA0.50.50.8-0.70.40.40.90.70.10.80.80.8-0.90.6
Tibia length1.13.15.7-1.31.30.51.92.3-0.02.02.12.0-2.41.7
Ambulatory time before self-admin0.81.24.21.11.3-1.40.60.1-2.0-0.5-0.7-0.50.2-1.5
Ambulatory time after self-admin1.01.22.31.50.8-1.50.2-0.4-1.5-1.0-1.0-1.01.0-1.4
Bone: tissue strength1.51.54.11.92.0-1.72.00.1-0.9-0.5-0.7-0.5-0.5-0.4
Total heroin consumption1.82.15.4-0.11.9-0.62.32.3-1.51.41.41.4-0.70.6
Bone: trabecular number0.20.40.90.1-0.4-0.0-0.6-0.5-0.6-0.6-0.7-0.60.8-0.9
Bone: trabecular spacing1.11.54.30.21.6-0.52.11.4-0.31.01.01.0-1.70.9
Bone: trabecular thickness0.20.20.8-0.5-0.90.6-0.9-0.40.3-0.1-0.2-0.10.4-0.1
Bone: trabecular tissue density0.30.41.5-0.20.00.30.30.21.20.60.60.6-0.71.2
Water consumed over 24 hours0.10.20.50.50.4-0.50.3-0.0-0.7-0.3-0.5-0.30.1-0.6
Number of responses in last shaping day0.30.30.60.80.2-0.4-0.3-0.6-0.3-0.6-0.8-0.50.5-0.7