Hub : Genes

LOC134486139

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC134486139 0.5 0.12 0.0e+00 0.42 0.42 0.45 0.44 5.6e-24 2.3e-24 4.5e-26 8.6e-26
2 NAcc intron excision ratio chr3_125821191_125825289 0.07 0.04 5.3e-09 0.06 0.06 0.05 0.05 8.8e-09 4.4e-09 6.6e-08 2.1e-08
3 PL gene expression LOC134486139 0.52 0.1 0.0e+00 0.5 0.51 0.51 0.51 1.7e-62 1.9e-64 3.6e-64 5.9e-64
4 IC gene expression LOC134486139 0.67 0.11 0.0e+00 0.29 0.28 0.3 0.19 9.7e-13 5.5e-12 2.6e-13 1.7e-08
5 Adipose gene expression LOC134486139 0.11 0.05 2.2e-12 0.09 0.08 0.07 0.08 3.4e-10 2.0e-09 2.3e-08 2.1e-09
6 NAcc gene expression LOC134486139 0.57 0.08 0.0e+00 0.64 0.64 0.65 0.65 1.2e-127 2.5e-129 8.4e-131 2.7e-130
7 Brain gene expression LOC134486139 0.55 0.12 0.0e+00 0.6 0.59 0.6 0.6 4.1e-69 2.6e-67 9.2e-69 8.2e-69
8 BLA mRNA stability LOC134486139 0.19 0.08 4.4e-10 0.2 0.18 0.17 0.19 1.2e-10 8.4e-10 1.4e-09 3.0e-10
9 pVTA mRNA stability LOC134486139 0.13 0.06 5.1e-09 0.11 0.11 0.13 0.12 3.5e-09 2.2e-09 1.2e-10 6.6e-10
10 pVTA gene expression LOC134486139 0.59 0.08 0.0e+00 0.56 0.55 0.57 0.57 1.7e-53 2.1e-52 1.0e-54 1.4e-55
11 NAcc intron excision ratio chr3_125793492_125804956 0.31 0.08 0.0e+00 0.36 0.35 0.36 0.36 1.0e-57 9.5e-55 4.4e-58 7.7e-57
12 Brain mRNA stability LOC134486139 0.32 0.1 0.0e+00 0.26 0.3 0.3 0.3 1.2e-24 1.6e-28 2.0e-28 1.1e-28
13 NAcc mRNA stability LOC134486139 0.23 0.07 0.0e+00 0.24 0.28 0.29 0.29 1.0e-36 3.4e-42 1.5e-44 7.3e-44
14 NAcc intron excision ratio chr3_125810442_125821079 0.04 0.02 6.0e-07 0.05 0.05 0.04 0.05 5.7e-08 4.3e-08 3.1e-06 6.2e-08
15 RMTg gene expression LOC134486139 0.29 0.13 7.8e-05 0.14 0.09 0.09 0.04 1.3e-04 2.9e-03 2.5e-03 3.4e-02
16 OFC gene expression LOC134486139 0.55 0.13 3.9e-10 0.33 0.27 0.35 0.33 1.1e-08 4.0e-07 4.5e-09 1.0e-08
17 LHb gene expression LOC134486139 0.66 0.11 2.4e-15 0.4 0.46 0.45 0.47 1.6e-10 2.3e-12 3.4e-12 9.3e-13
18 IL gene expression LOC134486139 0.64 0.12 1.7e-13 0.48 0.44 0.42 0.48 2.5e-13 7.8e-12 3.3e-11 3.9e-13
19 Eye gene expression LOC134486139 0.67 0.14 6.2e-05 0.06 0.09 -0.02 0.04 3.8e-02 1.8e-02 6.7e-01 8.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.01.82.2-1.2-1.41.3-1.3-1.3-1.4-1.5-1.4-1.51.4-1.21.4-1.2-1.2-1.4-1.41.4-1.41.2
Area under the delay curve1.32.05.4-0.9-1.61.7-1.4-1.3-1.5-1.4-1.3-2.01.2-1.21.3-2.3-1.3-1.4-0.91.3-1.30.6
BMI with tail2.89.713.9-3.7-3.53.3-3.2-3.4-3.4-3.3-3.4-3.23.4-3.03.3-2.6-2.5-3.2-2.53.0-3.11.9
BMI without tail3.317.629.6-5.4-4.24.4-4.5-4.5-4.5-4.7-4.6-4.14.6-4.04.2-3.3-3.7-4.0-3.43.8-3.93.2
Body weight3.013.218.6-4.3-4.23.8-3.8-3.9-3.9-3.9-3.9-3.63.9-3.43.8-3.2-2.8-3.7-2.93.6-3.72.3
Weight adjusted by age0.10.20.8-0.9-0.60.4-0.4-0.4-0.4-0.2-0.3-0.40.3-0.50.5-0.6-0.1-0.6-0.30.5-0.5-0.2
Bone surface0.40.91.4-1.1-0.90.8-0.8-1.0-0.9-1.0-0.9-0.71.0-0.81.0-0.5-0.7-1.2-0.91.1-1.11.0
Bone volume0.61.11.7-1.3-1.10.9-0.9-1.1-1.1-1.1-1.1-0.91.2-0.81.2-0.6-0.9-1.3-1.01.2-1.21.1
Breakpoint value in progressive ratio session0.10.10.40.3-0.10.00.10.1-0.10.10.1-0.10.0-0.00.2-0.4-0.3-0.4-0.40.6-0.60.5
Number of licking bursts0.00.10.70.0-0.40.2-0.0-0.0-0.2-0.1-0.2-0.00.2-0.10.2-0.2-0.4-0.4-0.40.3-0.30.8
Context. condit. distance diff. score1.82.23.7-1.7-1.51.4-1.4-1.9-1.5-1.6-1.6-1.01.7-1.41.7-0.8-1.4-1.4-1.21.5-1.51.6
Locomotion velocity, session 11.51.75.12.31.1-1.21.21.61.41.51.40.8-1.51.1-1.40.50.91.20.9-1.21.2-1.1
Locomotion distance, session 10.60.72.51.60.9-0.70.61.00.90.90.90.3-1.00.4-1.00.40.50.80.6-1.00.9-0.7
Locomotion velocity, session 22.02.44.5-0.5-1.61.6-1.7-1.2-1.5-1.4-1.4-2.11.3-1.81.3-1.9-1.7-1.6-1.81.4-1.51.1
Locomotion distance, session 20.00.10.50.70.3-0.1-0.10.30.20.20.2-0.1-0.3-0.3-0.3-0.0-0.20.1-0.1-0.30.20.2
Locomotion velocity, session 30.40.40.8-0.2-0.70.6-0.6-0.5-0.5-0.4-0.5-0.80.5-0.70.6-0.8-0.8-0.8-0.80.9-0.80.6
Locomotion distance, session 31.11.32.5-0.8-1.00.9-1.0-0.9-0.9-1.0-1.0-1.01.0-1.21.1-0.6-1.3-1.4-1.51.5-1.41.6
Stereotopy head waving bouts, day 30.81.01.8-1.2-1.31.0-0.9-1.1-1.1-1.1-1.1-1.11.1-0.51.0-1.1-0.6-1.0-0.71.0-0.90.4
Stereotopy head waving duration, day 31.41.73.1-1.1-1.71.5-1.3-1.4-1.4-1.4-1.3-1.71.3-1.01.2-1.7-1.0-1.2-1.11.3-1.20.5
Locomotion velocity, session 71.11.21.4-0.9-1.11.1-1.0-1.1-1.0-1.0-1.0-1.01.1-1.11.1-0.8-1.1-1.2-1.11.2-1.11.2
Locomotion distance, session 70.20.20.7-0.8-0.20.3-0.4-0.5-0.3-0.5-0.4-0.00.5-0.40.40.2-0.5-0.4-0.30.4-0.40.8
Stereotopy head waving bouts, day 70.40.40.90.70.5-0.80.80.60.70.60.70.6-0.61.0-0.60.50.70.60.6-0.40.4-0.6
Stereotopy head waving duration, day 70.50.61.20.60.5-0.90.90.70.70.80.80.8-0.71.1-0.70.61.00.70.8-0.50.5-0.9
Locomotion velocity, session 82.73.34.4-1.0-1.92.0-2.0-2.1-1.9-1.7-1.8-2.01.9-2.01.8-2.1-1.8-1.7-1.81.6-1.61.4
Locomotion distance, session 81.11.72.4-1.0-1.21.4-1.4-1.5-1.3-1.3-1.4-1.11.3-1.61.3-0.8-1.4-1.3-1.11.2-1.21.5
Degree of sensitization distance1.61.72.50.71.3-1.31.31.11.21.21.11.6-1.11.5-1.31.41.41.51.6-1.51.5-1.2
Degree of sensitization stereotypy0.91.01.80.70.9-1.21.21.01.00.91.01.2-0.91.4-0.91.21.10.91.1-0.70.8-0.8
Conditioned locomotion1.82.13.1-1.6-1.61.4-1.4-1.6-1.7-1.8-1.6-1.31.6-1.11.5-1.3-1.3-1.4-1.21.4-1.31.4
Cocaine response after cond. corrected0.10.10.80.4-0.30.2-0.1-0.3-0.1-0.1-0.2-0.20.2-0.30.2-0.4-0.7-0.2-0.70.4-0.30.9
Cocaine response after cond. not corrected0.10.11.01.0-0.10.1-0.1-0.10.10.2-0.0-0.2-0.0-0.30.1-0.3-0.6-0.0-0.60.2-0.10.7
Cocaine response before conditioning0.20.31.41.20.5-0.40.30.60.60.60.60.0-0.60.1-0.50.30.40.40.3-0.60.5-0.8
Saline control response0.10.10.6-0.7-0.2-0.20.2-0.00.1-0.2-0.00.10.00.7-0.00.60.70.10.5-0.10.1-0.8
Bone: connectivity density0.00.00.20.30.0-0.10.10.10.0-0.10.1-0.1-0.10.3-0.00.10.30.10.1-0.10.0-0.4
Bone: cortical apparent density0.91.42.7-0.11.2-1.41.41.21.21.01.11.6-1.11.4-1.11.61.21.01.2-0.80.9-0.4
Bone: cortical area1.11.72.4-1.5-1.41.4-1.4-1.3-1.4-1.3-1.3-1.31.3-1.41.4-1.1-1.1-1.5-1.11.4-1.40.9
Bone: cortical porosity1.11.22.80.4-0.91.2-1.3-0.8-0.9-0.9-0.8-1.60.8-1.50.9-1.7-1.5-0.9-1.50.8-0.81.0
Bone: cortical porosity1.41.63.1-0.0-1.21.4-1.4-1.1-1.1-1.1-1.0-1.71.0-1.61.1-1.8-1.5-1.2-1.61.1-1.11.0
Bone: cortical thickness1.11.92.6-1.2-1.41.4-1.5-1.3-1.4-1.3-1.3-1.61.3-1.51.4-1.4-1.3-1.5-1.31.4-1.50.9
Bone: cortical thickness0.40.51.3-0.5-0.80.4-0.4-0.6-0.5-0.6-0.5-0.50.6-0.50.7-0.5-0.7-0.8-0.90.9-0.81.1
Bone: cortical tissue density0.81.32.5-0.11.1-1.41.41.21.21.01.11.6-1.11.4-1.11.61.21.01.2-0.80.9-0.5
Condit. Reinf. active minus inactive responses3.13.54.91.41.7-2.02.01.81.81.91.92.0-1.82.0-1.72.02.21.62.0-1.71.7-1.9
Condit. Reinf. active-inactive response ratio0.20.30.7-0.10.3-0.50.60.30.40.50.50.6-0.40.6-0.30.50.80.40.8-0.40.4-0.8
Condit. Reinf. active responses5.46.98.92.22.4-2.92.82.62.52.52.52.8-2.43.0-2.53.03.02.42.7-2.42.4-2.5
Condit. Reinf. inactive responses2.83.75.82.01.9-2.22.12.01.91.81.82.1-1.72.2-1.92.42.01.81.6-1.71.7-1.4
Incentive salience index mean5.06.47.92.32.4-2.72.72.62.52.62.62.5-2.52.6-2.52.62.82.32.6-2.52.4-2.6
Condit. Reinf. lever presses4.26.27.12.52.4-2.62.52.62.52.52.62.3-2.52.4-2.52.62.72.42.5-2.52.4-2.5
Condit. Reinf. active minus inactive responses0.40.62.2-0.10.5-0.80.90.30.70.60.61.1-0.51.0-0.51.51.10.61.0-0.60.6-0.7
Condit. Reinf. active-inactive response ratio0.10.21.1-0.10.4-0.50.50.10.30.30.30.7-0.20.5-0.21.00.60.30.6-0.30.2-0.4
Condit. Reinf. active responses0.50.72.9-0.30.5-0.90.90.40.60.50.51.1-0.41.2-0.41.71.20.41.2-0.50.5-0.9
Condit. Reinf. inactive responses0.40.61.4-0.00.4-0.80.80.70.60.40.50.8-0.51.2-0.51.21.20.41.1-0.50.5-1.0
Condit. Reinf. lever presses0.71.12.60.50.6-1.11.20.90.90.70.90.9-0.81.5-0.81.51.60.61.3-0.70.7-1.5
Condit. Reinf. lever reinforcers received1.01.44.20.20.8-1.21.30.81.10.90.91.4-0.91.6-0.82.01.70.81.6-0.90.8-1.3
Conditioned reinforcement - actives0.00.10.20.50.1-0.10.10.20.20.40.3-0.3-0.30.1-0.1-0.20.00.4-0.0-0.10.1-0.3
Conditioned reinforcement - inactives0.30.91.5-0.5-1.00.9-0.8-0.9-0.9-0.8-0.9-1.11.0-0.81.0-0.7-1.0-0.8-1.21.1-1.11.2
Conditioned locomotion0.30.51.71.00.4-0.40.40.60.60.80.7-0.1-0.70.5-0.6-0.10.80.90.7-0.60.7-1.3
Patch foraging indifference point 0 sec0.10.22.5-0.10.0-0.20.10.20.20.20.4-0.4-0.30.4-0.20.10.80.10.4-0.10.1-1.6
Patch foraging indifference point AUC0.71.73.11.81.1-1.51.41.51.51.51.61.2-1.51.4-1.31.01.21.10.9-1.01.0-1.0
Delay disc. indifference point, 0s delay0.30.31.40.40.4-0.50.40.60.50.50.60.0-0.60.5-0.5-0.20.70.40.6-0.60.6-1.2
Delay disc. indifference point, 16s delay0.50.82.7-0.3-1.10.9-0.8-0.7-0.8-0.6-0.6-1.20.5-0.80.8-1.6-0.9-0.9-0.71.0-1.00.4
Delay disc. indifference point, 2s delay0.30.40.8-0.8-0.60.7-0.7-0.7-0.7-0.9-0.6-0.60.7-0.50.6-0.5-0.3-0.6-0.20.5-0.60.2
Delay disc. indifference point, 24s delay0.61.03.11.81.0-0.81.01.01.01.01.10.5-1.21.0-1.00.20.81.01.2-1.01.0-1.1
Delay disc. indifference point, 4s delay0.80.92.5-0.1-1.01.1-0.9-0.9-1.0-0.9-0.8-1.50.8-0.80.8-1.6-0.9-0.9-0.80.7-0.70.4
Delay disc. indifference point, 8s delay2.13.57.7-1.4-2.12.1-1.9-1.8-2.0-1.8-1.8-2.41.7-1.71.8-2.8-1.6-1.9-1.41.9-1.90.9
Indifference point function ln k2.06.18.3-2.9-2.22.7-2.7-2.7-2.7-2.7-2.7-2.42.7-2.72.5-1.9-2.4-2.3-2.12.2-2.22.2
Indifference point function log k2.06.18.3-2.9-2.22.7-2.7-2.7-2.7-2.7-2.7-2.42.7-2.72.5-1.9-2.4-2.3-2.12.2-2.22.2
Patch foraging total patch changes 0 sec0.10.22.1-0.00.0-0.30.20.20.30.20.4-0.3-0.30.4-0.20.10.80.10.4-0.10.1-1.5
Patch foraging total patch changes 12 sec1.01.32.70.91.0-1.31.11.41.31.11.30.8-1.31.2-1.10.91.40.90.9-0.80.7-1.6
Patch foraging total patch changes 18 sec0.61.31.81.20.9-1.31.11.21.31.31.31.1-1.21.3-1.10.91.31.01.0-1.11.1-1.3
Patch foraging total patch changes 24 sec0.00.20.5-0.2-0.70.4-0.3-0.5-0.3-0.2-0.2-0.60.2-0.20.4-0.7-0.0-0.3-0.20.4-0.4-0.5
Patch foraging total patch changes 6 sec0.50.81.70.90.8-0.90.91.00.90.81.00.4-0.91.0-0.80.71.10.70.8-0.70.7-1.3
Patch foraging time to switch 0 sec1.03.74.81.21.9-2.01.91.92.02.01.91.9-1.91.9-2.01.72.21.81.9-1.92.0-2.2
Patch foraging water rate 0 sec0.41.52.1-1.3-1.31.2-1.0-1.3-1.4-1.5-1.3-0.91.4-0.91.4-0.7-1.1-1.3-1.01.3-1.31.4
Patch foraging water rate 12 sec0.52.14.9-0.8-1.31.4-1.2-1.5-1.4-1.5-1.5-1.21.5-1.31.5-0.8-1.7-1.5-1.71.5-1.52.2
Patch foraging water rate 18 sec1.43.14.0-1.1-1.61.9-1.7-1.7-1.7-1.8-1.8-1.81.8-1.71.8-1.5-2.0-1.9-1.91.8-1.81.9
Patch foraging water rate 24 sec1.01.42.8-1.4-0.90.8-0.9-1.1-1.2-1.5-1.2-0.71.4-0.81.2-0.2-1.1-1.4-1.21.3-1.31.7
Patch foraging water rate 6 sec0.10.21.70.4-0.20.10.0-0.3-0.3-0.3-0.20.20.3-0.10.40.2-0.5-0.4-0.50.5-0.51.3
Seeking ratio, delayed vs. immediate footshock0.20.20.6-0.4-0.50.4-0.4-0.6-0.5-0.6-0.6-0.20.6-0.30.60.2-0.4-0.6-0.60.3-0.40.8
Distance traveled before self-admin0.41.01.3-0.5-1.01.1-1.1-0.9-1.1-1.2-1.1-1.21.1-0.90.9-0.9-1.0-1.1-0.80.9-0.90.6
Distance traveled after self-admin0.00.00.10.1-0.20.1-0.3-0.0-0.2-0.3-0.2-0.10.2-0.00.10.0-0.1-0.3-0.30.2-0.30.1
Extensor digitorum longus weight0.51.92.4-1.4-1.31.4-1.5-1.3-1.3-1.5-1.3-1.41.4-1.41.3-1.3-1.4-1.4-1.41.5-1.41.2
Bone: elastic displacement0.00.00.20.40.1-0.1-0.10.30.1-0.10.1-0.3-0.2-0.0-0.1-0.10.1-0.1-0.1-0.00.0-0.4
Bone: elastic work0.10.10.2-0.3-0.30.2-0.3-0.0-0.3-0.4-0.2-0.50.3-0.10.3-0.20.1-0.4-0.30.5-0.4-0.2
Bone: endosteal estimation0.20.61.3-1.0-0.70.8-0.7-0.8-0.8-0.8-0.8-0.30.8-0.80.8-0.4-0.8-0.9-0.50.7-0.61.1
Bone: endosteal perimeter0.10.10.3-0.5-0.20.4-0.4-0.3-0.4-0.4-0.4-0.00.4-0.60.4-0.2-0.4-0.4-0.10.2-0.20.5
Epididymis fat weight0.62.94.5-1.5-1.51.9-2.0-1.6-1.7-1.8-1.6-2.11.5-2.11.5-1.9-1.8-1.6-1.91.4-1.51.1
Delta time in closed arm before/after self-admin0.10.10.3-0.50.20.4-0.1-0.5-0.3-0.2-0.3-0.10.3-0.30.20.3-0.40.0-0.10.0-0.10.6
Delta time in open arm before/after self-admin2.42.84.0-1.9-2.01.4-1.5-1.7-1.7-2.0-1.8-1.31.8-1.11.8-1.3-1.4-1.7-1.61.8-1.81.9
Diff in mean of infusions in LGA sessions0.71.32.31.01.4-1.11.31.01.01.11.01.1-1.01.5-1.11.11.21.11.5-1.01.0-1.2
Delay discount exponential model param1.31.84.80.71.5-1.61.31.31.41.31.21.9-1.21.2-1.22.21.31.20.9-1.21.2-0.6
Extinction: sum of active levers before priming0.30.52.01.40.8-0.60.60.70.81.20.70.4-0.80.5-0.70.50.40.70.4-0.50.5-0.6
Active lever presses in extinction session 60.10.10.50.5-0.10.2-0.20.2-0.00.00.1-0.5-0.2-0.3-0.0-0.7-0.3-0.0-0.20.1-0.1-0.1
Bone: final force0.61.11.9-1.2-1.00.9-1.0-0.9-1.1-1.1-1.1-0.81.1-1.01.2-0.3-0.8-1.2-0.91.3-1.41.0
Bone: final moment0.71.11.9-1.3-1.00.9-1.0-0.9-1.1-1.1-1.1-0.81.1-1.01.2-0.3-0.8-1.2-0.91.3-1.41.0
Food consumed during 24 hour testing period0.10.20.70.7-0.40.3-0.2-0.3-0.2-0.1-0.2-0.40.3-0.30.3-0.2-0.5-0.4-0.80.5-0.50.7
Glucose2.43.85.4-2.3-1.81.9-2.0-1.9-1.9-2.0-1.9-1.81.9-2.01.9-1.4-1.9-2.1-2.02.0-2.01.9
Heart weight2.43.95.7-2.4-2.22.2-2.0-2.3-2.1-1.9-2.0-1.92.0-2.02.1-1.8-1.7-1.9-1.51.9-2.01.4
Delay discount hyperbolic model param1.31.64.10.71.5-1.51.31.31.41.31.21.7-1.11.1-1.22.01.11.20.8-1.11.1-0.6
Intermittent access intake day 1-15 change0.84.57.5-2.0-2.51.7-1.9-1.8-1.9-2.0-1.9-1.72.0-2.02.2-1.7-2.1-2.3-2.72.4-2.42.6
Intermittent access intake escalation0.84.57.7-2.1-2.61.7-1.9-1.8-1.9-1.9-1.9-1.72.0-1.92.2-1.8-2.0-2.4-2.82.5-2.52.4
Intermittent access intake escalation 23.25.49.8-1.6-2.62.0-2.1-2.0-2.1-2.1-2.1-2.02.1-2.12.3-2.3-2.5-2.5-3.12.5-2.52.9
Intermitt. access day 1 inactive lever presses0.00.42.6-1.6-0.10.8-0.5-0.7-0.7-0.8-0.7-0.30.6-0.50.4-0.2-0.4-0.20.20.2-0.20.1
Intermitt. access day 15 inactive lever presses0.21.02.9-1.7-0.81.0-1.1-1.0-1.0-1.1-1.1-0.91.1-1.11.0-0.6-1.0-0.8-0.90.9-0.91.1
Intermitt. access escalation Index0.20.51.5-0.50.7-0.70.60.40.60.40.51.0-0.40.7-0.61.21.00.31.1-0.60.6-0.8
Intermittent access day 1 total infusions0.10.30.80.60.6-0.50.60.60.50.80.60.1-0.60.6-0.50.30.50.60.3-0.50.5-0.9
Intermittent access day 15 total infusions0.51.22.3-1.4-1.30.8-0.9-0.9-1.0-0.8-0.9-1.01.0-0.81.1-0.9-0.9-1.1-1.51.3-1.31.0
Intermittent access terminal intake (last 3 days)1.42.54.4-1.6-1.71.3-1.4-1.4-1.4-1.2-1.4-1.41.5-1.41.6-1.4-1.6-1.7-2.11.9-1.91.8
Intermittent access total infusions0.30.30.8-0.7-0.70.4-0.5-0.5-0.5-0.3-0.5-0.60.5-0.40.6-0.5-0.5-0.5-0.90.8-0.80.5
Intermittent access day 1 locomotion0.10.10.60.0-0.10.4-0.3-0.1-0.20.1-0.1-0.80.1-0.30.1-0.7-0.00.1-0.00.0-0.0-0.7
Intermittent access day 15 total locomotion0.62.53.5-1.5-1.91.6-1.5-1.7-1.6-1.5-1.6-1.51.6-1.41.6-1.5-1.5-1.5-1.71.6-1.51.6
Intermittent access total locomotion0.40.41.1-0.6-0.90.7-0.7-0.7-0.6-0.5-0.6-0.90.6-0.70.6-1.0-0.5-0.4-0.60.6-0.60.3
Intermittent access standard deviation0.63.05.2-1.3-2.01.4-1.7-1.4-1.5-1.4-1.5-1.31.6-1.81.7-1.6-1.8-1.8-2.32.0-2.02.2
Left kidney weight1.512.216.3-3.2-3.74.0-4.0-3.8-3.8-4.0-3.8-4.03.7-3.63.5-3.5-3.2-3.1-2.72.8-2.92.4
Right kidney weight2.416.623.3-3.7-4.54.6-4.6-4.3-4.4-4.4-4.3-4.84.3-4.34.1-4.3-3.7-3.5-3.63.5-3.62.5
Cocaine induced anxiety0.10.31.4-1.20.20.7-0.7-0.5-0.4-0.5-0.5-0.60.3-0.90.1-0.4-0.20.40.6-0.40.4-0.6
Post-drug Anxiety0.60.73.5-1.9-0.21.2-1.1-1.0-0.9-1.0-1.0-0.70.9-1.10.6-0.5-0.70.10.2-0.00.00.2
Baseline Anxiety0.00.10.2-0.4-0.20.2-0.0-0.3-0.2-0.3-0.30.30.30.10.20.3-0.2-0.2-0.10.2-0.20.5
Tail length1.79.413.0-3.6-3.13.2-3.3-3.2-3.2-3.3-3.3-2.83.3-3.03.1-2.5-2.8-2.9-2.72.9-3.02.7
Length with tail0.94.05.3-2.0-2.32.0-2.1-2.0-2.1-2.1-2.0-1.92.0-1.92.1-1.9-1.6-2.1-1.72.2-2.21.5
Length without tail0.31.42.6-0.2-1.61.1-1.0-1.1-1.1-0.9-1.0-1.31.0-1.21.3-1.3-0.9-1.5-1.21.6-1.60.9
Times rat made contact with spout0.10.10.30.20.2-0.20.30.40.20.30.20.2-0.30.6-0.3-0.10.40.30.4-0.30.3-0.5
Lifetime Intake0.10.20.5-0.2-0.50.3-0.3-0.2-0.3-0.1-0.2-0.60.3-0.30.4-0.5-0.4-0.4-0.70.6-0.60.3
Liver weight, left1.93.34.7-2.1-2.21.7-1.7-1.7-1.9-2.0-1.8-1.91.9-1.41.9-1.2-1.3-2.1-1.62.1-2.21.2
Liver weight, right1.32.23.3-1.8-1.81.4-1.4-1.4-1.5-1.5-1.5-1.71.6-1.21.5-1.3-1.0-1.7-1.41.7-1.70.8
Locomotor activity0.20.30.50.60.7-0.40.50.50.60.60.60.3-0.60.3-0.50.50.30.60.6-0.60.6-0.5
Locomotor testing distance0.20.41.00.81.0-0.50.60.60.70.80.70.3-0.70.3-0.70.70.40.70.6-0.80.8-0.6
Locomotor testing rearing0.51.93.21.41.8-1.41.31.41.41.31.41.3-1.41.1-1.51.51.11.51.2-1.61.6-1.0
Locomotion in novel chamber0.10.10.3-0.40.10.3-0.4-0.2-0.3-0.2-0.2-0.20.2-0.50.30.1-0.3-0.3-0.40.4-0.40.1
Locomotion in novel chamber post-restriction0.72.23.1-1.2-1.81.5-1.5-1.8-1.6-1.6-1.8-1.21.7-1.21.6-1.3-1.3-1.3-1.41.4-1.41.4
Fecal boli incidents, locomotor time 10.00.10.20.40.3-0.30.00.20.30.30.40.0-0.3-0.1-0.1-0.3-0.10.3-0.10.1-0.0-0.1
Change in fecal boli incidents, locomotor task1.92.02.5-1.1-1.41.5-1.4-1.5-1.5-1.4-1.6-1.31.6-1.41.5-0.9-1.3-1.5-1.31.4-1.51.3
Time >=10cm from walls, locomotor time 10.10.10.40.2-0.30.00.0-0.2-0.2-0.4-0.20.00.30.30.40.3-0.2-0.1-0.50.5-0.50.7
Bouts of movement, locomotor time 12.53.35.22.31.8-1.91.82.01.91.92.01.5-2.01.7-2.01.11.52.01.5-1.92.0-1.3
Total resting periods, locomotor time 13.54.15.32.32.1-2.12.02.22.12.12.11.8-2.11.9-2.21.51.72.21.8-2.12.2-1.5
Rest time, locomotor task time 10.30.40.70.80.6-0.70.50.70.60.70.60.6-0.50.6-0.70.60.70.80.6-0.60.6-0.6
Distance moved, locomotor task time 10.10.30.80.00.4-0.60.80.60.50.50.60.7-0.60.9-0.50.50.70.20.6-0.50.5-0.5
Vertical activity count, locomotor time 10.00.00.3-0.6-0.20.1-0.0-0.1-0.2-0.3-0.10.20.20.10.20.00.0-0.3-0.00.1-0.10.2
Time >=10cm from walls, locomotor time 21.02.77.8-2.8-2.01.6-1.6-1.9-1.9-2.0-1.9-1.31.9-0.81.8-1.3-0.9-1.4-0.91.7-1.70.7
Bouts of movement, locomotor time 20.10.20.70.30.2-0.50.60.30.40.30.40.5-0.20.9-0.20.70.60.00.40.1-0.1-0.2
Total resting periods, locomotor time 20.10.20.60.40.3-0.60.50.40.40.40.50.6-0.30.8-0.30.70.60.10.40.0-0.0-0.2
Rest time, locomotor task time 21.42.45.02.21.7-1.51.31.81.61.71.61.4-1.71.0-1.71.11.11.71.3-1.71.6-1.1
Distance moved, locomotor task time 20.30.42.6-1.6-0.70.6-0.4-0.6-0.7-0.8-0.6-0.50.7-0.10.6-0.5-0.2-0.8-0.20.4-0.4-0.0
Vertical activity count, locomotor time 20.41.03.1-1.7-1.10.8-0.7-0.9-1.1-1.2-1.1-0.71.1-0.41.1-0.4-0.4-1.4-0.71.1-1.10.6
Light reinforcement 11.15.210.21.32.0-2.32.32.22.22.12.22.0-2.12.7-2.12.43.02.02.4-2.12.0-3.2
Light reinforcement 21.22.75.52.31.6-1.81.62.01.71.51.71.4-1.71.7-1.71.61.61.41.1-1.31.3-1.5
Bone: marrow area0.20.61.2-1.0-0.70.8-0.7-0.9-0.8-0.8-0.8-0.30.8-0.80.8-0.5-0.8-0.9-0.50.7-0.71.1
Bone: maximum diameter0.30.51.5-1.2-0.70.8-0.7-0.7-0.7-0.6-0.7-0.40.8-0.80.8-0.3-0.5-0.9-0.40.8-0.70.5
Bone: maximum force0.81.72.5-1.5-1.31.3-1.3-1.2-1.3-1.4-1.4-1.31.3-1.21.4-0.8-0.9-1.4-1.11.5-1.60.8
Bone: maximum moment0.81.52.3-1.5-1.31.2-1.3-1.2-1.3-1.3-1.3-1.21.3-1.21.4-0.7-0.9-1.3-1.11.4-1.50.8
Mean time between licks in bursts0.00.20.70.8-0.20.2-0.20.0-0.1-0.0-0.0-0.70.0-0.30.1-0.7-0.6-0.3-0.80.3-0.40.5
Mean num. licks in bursts0.10.20.9-0.10.4-0.30.20.20.30.20.20.2-0.30.4-0.30.30.60.50.5-0.30.3-0.9
Cd content in liver0.10.10.4-0.6-0.40.3-0.3-0.5-0.4-0.3-0.4-0.30.4-0.20.4-0.4-0.3-0.4-0.40.5-0.40.3
Co content in liver0.60.71.9-0.7-0.80.9-1.0-0.8-0.8-0.7-0.8-0.90.7-0.90.8-1.4-1.0-0.7-0.80.8-0.70.7
Cu content in liver0.10.10.60.0-0.20.2-0.1-0.3-0.3-0.1-0.40.10.3-0.30.3-0.2-0.4-0.1-0.20.2-0.20.8
Fe content in liver3.74.57.30.92.2-2.42.42.22.12.12.22.7-2.02.3-2.12.42.21.92.2-1.91.9-1.5
K content in liver0.60.60.9-0.7-0.80.8-0.7-0.9-0.9-0.7-1.0-0.60.9-0.80.9-0.6-0.8-0.8-0.70.7-0.71.0
Mg content in liver2.22.43.6-1.7-1.61.5-1.4-1.7-1.6-1.6-1.7-1.11.7-1.41.6-1.1-1.5-1.6-1.31.6-1.51.9
Mn content in liver0.91.02.6-1.6-1.21.1-1.0-1.1-1.1-1.2-1.1-1.01.1-0.71.0-0.7-0.7-0.9-0.60.9-0.90.6
Na content in liver0.20.20.50.70.5-0.50.50.40.40.40.30.4-0.40.3-0.40.70.20.40.1-0.50.40.1
Rb content in liver4.75.56.6-2.3-2.52.5-2.4-2.6-2.5-2.4-2.5-2.32.4-2.32.4-2.4-2.2-2.2-2.02.3-2.31.9
Se content in liver0.10.10.2-0.4-0.50.10.0-0.3-0.3-0.2-0.30.00.30.20.3-0.0-0.1-0.2-0.10.3-0.20.4
Sr content in liver0.10.10.30.2-0.10.2-0.20.1-0.1-0.20.1-0.50.0-0.20.0-0.4-0.3-0.2-0.40.2-0.20.1
Zn content in liver0.10.10.6-0.20.4-0.40.40.20.20.40.10.8-0.20.2-0.20.50.10.20.3-0.20.20.5
Bone: minimum diameter1.12.13.0-1.6-1.51.7-1.6-1.5-1.5-1.5-1.4-1.61.4-1.71.4-1.7-1.3-1.5-1.11.4-1.30.8
Time in familiar zone, hab. session 10.40.51.11.00.8-0.80.70.90.70.80.80.7-0.80.7-0.80.40.40.80.3-0.60.6-0.2
Time in novel zone, hab. session 10.70.82.6-1.6-1.00.9-0.8-1.1-1.0-0.9-1.0-0.61.0-0.71.1-0.6-0.5-0.9-0.31.0-1.00.4
Total zone transitions, hab. session 10.30.51.11.00.8-0.60.60.80.80.90.90.3-0.90.4-0.80.30.40.70.4-0.70.6-0.7
Total locomotion distance, hab. session 10.50.72.01.40.9-0.70.70.81.00.91.00.5-1.00.4-0.90.50.61.00.8-0.90.9-0.9
Locomotion velocity, hab. session 11.01.53.31.81.3-1.01.01.21.31.31.40.7-1.50.7-1.30.80.91.31.1-1.31.2-1.3
Time in familiar zone, hab. session 20.10.10.4-0.00.3-0.40.50.20.40.40.30.6-0.30.6-0.30.60.40.30.4-0.20.3-0.2
Time in novel zone, hab. session 20.70.81.3-0.8-0.91.0-1.0-0.8-1.0-0.9-0.9-1.20.9-1.00.8-1.1-0.8-0.9-0.90.8-0.90.5
Total zone transitions, hab. session 20.10.10.60.6-0.20.3-0.40.0-0.1-0.2-0.1-0.80.0-0.60.1-0.4-0.5-0.3-0.60.2-0.30.3
Total locomotion distance, hab. session 20.10.10.40.60.3-0.20.20.40.40.20.3-0.0-0.40.2-0.30.40.30.30.3-0.30.2-0.4
Locomotion velocity, hab. session 20.20.30.80.90.6-0.40.40.70.60.40.60.2-0.70.4-0.60.60.50.50.5-0.60.5-0.7
Novel to familiar place preference ratio0.10.21.3-1.1-0.30.4-0.3-0.3-0.4-0.6-0.6-0.10.40.00.3-0.10.1-0.10.30.1-0.1-0.3
Novelty place preference0.10.21.4-1.2-0.30.4-0.4-0.4-0.5-0.6-0.6-0.10.4-0.00.3-0.20.1-0.10.30.1-0.1-0.3
Time in novel zone, NPP test0.10.21.3-1.2-0.30.4-0.3-0.4-0.4-0.5-0.5-0.00.40.00.3-0.20.1-0.10.40.1-0.1-0.3
Total zone transitions, NPP test0.10.21.91.40.00.2-0.2-0.10.10.00.1-0.5-0.1-0.6-0.0-0.5-0.6-0.1-0.6-0.0-0.00.6
Total locomotion distance, NPP test0.20.30.70.7-0.40.7-0.6-0.5-0.4-0.4-0.4-0.80.3-0.90.4-0.8-0.8-0.2-0.60.2-0.20.5
Locomotion velocity, NPP test0.30.41.00.7-0.30.7-0.7-0.5-0.4-0.5-0.4-1.00.3-1.00.3-0.9-0.9-0.2-0.80.2-0.20.5
Intraocular pressure0.91.42.31.31.4-1.31.31.41.41.41.51.1-1.40.9-1.30.91.00.80.8-1.01.0-1.2
Delta distance traveled before/after self-admin0.60.71.00.60.8-1.00.80.90.90.80.80.9-0.80.9-0.90.70.90.80.6-0.80.8-0.7
Delta ambulatory time before/after self-admin1.22.02.51.11.3-1.61.41.41.41.51.41.5-1.51.5-1.51.21.61.51.4-1.41.5-1.4
Parametrial fat weight0.20.51.50.90.9-0.30.30.70.50.50.60.4-0.70.2-0.80.30.61.01.0-0.90.8-1.2
Pavlov. Cond. lever latency0.70.91.7-1.3-0.90.8-0.8-0.8-1.0-1.0-1.0-0.51.0-0.50.9-0.7-0.9-1.0-0.91.2-1.11.2
Pavlov. Cond. magazine entry latency1.92.44.51.41.5-1.41.41.31.51.51.51.3-1.41.3-1.41.91.91.61.8-1.61.5-2.1
Pavlov. Cond. change in total contacts0.00.00.30.30.2-0.0-0.00.00.10.10.20.1-0.1-0.3-0.10.50.10.20.1-0.30.1-0.1
Pavlov. Cond. index score1.82.33.51.71.5-1.41.31.31.51.51.61.1-1.51.1-1.41.51.61.61.6-1.71.5-1.9
Pavlov. Cond. latency score1.82.33.91.71.5-1.31.31.31.51.51.61.1-1.51.0-1.41.41.61.61.6-1.71.6-2.0
Pavlov. Cond. lever contacts1.21.52.61.61.2-1.01.01.11.31.21.30.8-1.30.8-1.21.11.11.31.2-1.51.4-1.5
Pavlov. Cond. magazine entry number0.81.12.4-1.1-0.90.9-0.9-0.8-1.0-1.0-1.0-0.71.0-0.70.8-1.3-1.3-1.0-1.21.1-0.91.6
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.5-0.40.1-0.1-0.2-0.3-0.4-0.30.00.5-0.00.40.1-0.4-0.6-0.60.7-0.61.1
Pavlov. Cond. lever-magazine prob. diff.1.41.83.01.71.4-1.21.11.21.41.41.40.9-1.40.8-1.21.41.31.41.3-1.51.4-1.6
Pavlov. Cond. response bias1.31.62.51.51.3-1.21.21.11.31.31.31.1-1.20.9-1.11.61.31.31.3-1.41.2-1.4
Pavlov. Cond. lever latency0.10.20.70.50.20.2-0.3-0.1-0.10.0-0.1-0.2-0.1-0.6-0.0-0.8-0.80.2-0.6-0.10.10.8
Pavlov. Cond. magazine entry latency0.91.32.80.00.9-1.31.41.01.00.90.91.3-0.81.6-0.91.71.70.81.3-0.80.7-1.3
Pavlov. Cond. change in total contacts0.30.72.5-0.00.6-0.90.90.60.70.60.61.0-0.51.0-0.61.61.20.51.0-0.60.5-0.9
Pavlov. Cond. index score0.40.72.5-0.30.5-0.90.90.70.60.50.50.9-0.41.2-0.51.61.30.41.0-0.40.3-1.0
Pavlov. Cond. latency score0.30.41.9-0.20.3-0.70.70.50.40.30.40.7-0.21.0-0.41.41.10.20.7-0.20.2-0.7
Pavlov. Cond. lever contacts0.20.41.4-0.50.0-0.50.60.30.30.30.30.5-0.11.0-0.21.11.20.00.9-0.20.1-1.1
Pavlov. Cond. magazine entry number0.60.72.20.2-0.60.9-1.1-0.6-0.6-0.6-0.6-1.10.5-1.20.6-1.5-1.3-0.6-1.10.6-0.50.9
Pavlov. Cond. intertrial magazine entries0.40.92.2-0.6-1.11.1-1.0-0.9-0.9-0.8-0.8-1.20.8-0.90.9-1.5-1.0-0.9-0.90.9-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.50.72.5-0.20.5-0.91.00.70.60.60.61.0-0.41.3-0.61.61.40.51.0-0.50.5-1.0
Pavlov. Cond. response bias0.50.72.2-0.60.2-0.80.90.50.50.40.50.9-0.31.3-0.41.51.50.31.2-0.30.3-1.2
Time in closed arm before self-admin2.03.54.51.91.9-2.02.02.11.91.81.92.1-1.92.1-1.81.81.81.71.9-1.61.6-1.5
Time in closed arm after self-admin2.52.94.21.61.9-1.71.91.61.71.51.71.9-1.61.8-1.62.11.61.81.7-1.61.6-1.2
Time in open arm before self-admin0.00.10.2-0.1-0.20.3-0.3-0.3-0.2-0.0-0.1-0.30.2-0.30.1-0.3-0.1-0.4-0.20.1-0.1-0.1
Time in open arm after self-admin5.25.77.3-2.3-2.72.2-2.3-2.4-2.4-2.5-2.5-2.32.4-2.12.4-2.3-2.3-2.6-2.52.4-2.42.4
Bone: periosteal estimation0.61.31.8-1.3-1.21.2-1.2-1.2-1.2-1.2-1.2-0.91.2-1.21.2-1.0-1.0-1.3-0.91.2-1.11.1
Bone: periosteal perimeter0.71.32.0-1.0-1.11.3-1.4-1.1-1.2-1.1-1.1-1.21.1-1.41.2-1.3-1.1-1.2-0.91.1-1.10.7
Bone: post-yield work0.40.71.1-0.3-0.60.9-0.9-0.8-0.7-0.7-0.8-0.90.7-1.10.8-0.7-1.1-0.8-0.90.7-0.81.0
Progressive ratio test 1 active lever presses0.20.30.50.50.6-0.60.70.50.50.70.60.3-0.50.6-0.50.60.60.40.4-0.40.4-0.5
Progressive ratio test 1 breakpoint0.20.30.40.50.6-0.60.70.50.50.70.50.3-0.50.6-0.50.60.60.40.4-0.40.4-0.5
Progressive ratio test 1 inactive lever presses0.00.10.30.10.6-0.30.30.20.20.30.20.3-0.20.3-0.30.60.30.40.3-0.40.4-0.2
Progressive ratio test 2 active lever presses0.10.10.30.10.2-0.40.50.20.30.40.20.2-0.20.5-0.10.50.40.1-0.00.0-0.0-0.2
Progressive ratio test 2 breakpoint0.00.00.2-0.10.0-0.30.40.10.20.30.10.1-0.10.40.00.40.30.0-0.20.1-0.1-0.1
Progressive ratio test 2 inactive lever presses0.10.20.8-0.9-0.40.4-0.4-0.5-0.4-0.3-0.5-0.50.5-0.40.5-0.2-0.4-0.3-0.50.5-0.50.4
Incentive Sensitization - Responses0.00.10.3-0.2-0.40.2-0.2-0.3-0.2-0.1-0.3-0.40.3-0.20.4-0.2-0.3-0.4-0.50.5-0.50.3
Incentive Sensitization - Breakpoint0.00.10.2-0.2-0.30.1-0.1-0.2-0.1-0.0-0.2-0.30.2-0.10.3-0.1-0.1-0.3-0.40.4-0.40.2
Sum of active levers in priming session hrs 5-60.30.30.90.1-0.60.3-0.3-0.3-0.40.0-0.3-0.40.3-0.50.4-0.7-0.7-0.3-1.00.7-0.71.0
Progressive ratio0.10.31.31.20.6-0.50.70.70.50.50.60.4-0.50.6-0.50.70.50.30.4-0.30.3-0.3
Food seeking constrained by brief footshock0.00.00.10.1-0.10.2-0.0-0.1-0.3-0.3-0.2-0.40.2-0.00.0-0.3-0.10.1-0.00.1-0.20.1
Seeking ratio, punishment vs. effort0.00.00.1-0.3-0.10.1-0.2-0.2-0.1-0.1-0.2-0.10.1-0.10.1-0.2-0.00.1-0.00.0-0.0-0.0
Retroperitoneal fat weight0.31.45.0-2.2-1.21.3-1.3-1.3-1.4-1.5-1.3-1.21.3-1.01.1-0.6-0.3-1.3-0.31.0-1.0-0.4
Reaction time number correct1.86.37.6-2.4-2.72.4-2.4-2.7-2.5-2.6-2.5-2.32.6-2.32.7-1.8-2.4-2.8-2.62.5-2.62.7
Reaction time mean minus median0.00.22.3-1.5-0.60.3-0.3-0.4-0.3-0.4-0.4-0.30.3-0.20.4-0.3-0.1-0.5-0.30.4-0.50.2
Reaction time mean minus median AUC0.21.45.7-2.4-1.41.1-1.1-1.2-1.2-1.1-1.2-1.01.1-1.01.1-0.9-0.7-1.1-0.71.1-1.00.6
Reaction time num false alarms0.00.00.3-0.5-0.10.3-0.1-0.1-0.1-0.1-0.2-0.10.1-0.10.10.0-0.00.20.2-0.20.2-0.1
Reaction time num false alarms AUC0.10.10.3-0.30.3-0.20.20.20.30.20.10.4-0.20.3-0.30.50.30.50.6-0.50.5-0.3
Reaction time trials correct on left1.86.37.6-2.4-2.72.4-2.4-2.7-2.5-2.6-2.5-2.32.6-2.32.7-1.8-2.4-2.8-2.62.5-2.62.7
Reaction time trials on left1.86.07.3-2.3-2.62.3-2.3-2.6-2.5-2.6-2.4-2.22.6-2.22.7-1.8-2.3-2.7-2.52.5-2.52.6
Reaction time mean0.71.62.80.41.2-1.61.51.41.31.11.21.6-1.21.7-1.31.61.41.01.2-1.01.1-0.8
Reaction time mean AUC0.30.81.60.00.9-1.11.01.00.90.70.81.2-0.81.3-0.91.11.00.70.9-0.70.7-0.6
Median of all reaction times2.13.34.81.31.9-2.12.02.01.81.71.82.1-1.72.2-1.82.01.91.61.6-1.61.6-1.2
Reaction time omissions0.30.41.0-0.70.1-0.60.60.30.50.40.40.6-0.50.8-0.50.51.00.41.0-0.70.7-1.0
Reaction time false alarm rate1.41.92.90.81.5-1.21.21.41.31.31.21.4-1.31.3-1.41.21.41.71.7-1.61.6-1.5
Reaction time premature initiation rate3.65.67.81.42.8-2.32.22.42.31.92.22.4-2.32.3-2.42.52.52.62.7-2.42.4-2.5
Reaction time premature initiations0.30.92.20.11.3-1.00.90.80.90.50.81.1-0.81.0-0.91.51.11.01.3-0.90.9-0.9
Std. dev. reaction times0.00.11.9-1.4-0.2-0.20.10.00.1-0.0-0.00.20.00.3-0.00.30.4-0.20.30.1-0.1-0.3
Reaction time trials completed1.86.07.3-2.3-2.62.3-2.3-2.6-2.5-2.6-2.4-2.22.6-2.22.7-1.8-2.3-2.7-2.52.5-2.52.6
Reaction time trials AUC1.55.36.7-2.3-2.42.1-2.1-2.5-2.3-2.4-2.3-2.02.4-2.02.5-1.5-2.2-2.6-2.42.4-2.42.6
Run reversals in cocaine runway, females1.41.62.9-1.2-1.01.4-1.3-1.2-1.3-1.2-1.1-1.21.1-1.71.1-1.1-1.6-1.4-1.21.1-1.11.6
Run reversals in cocaine runway, males0.10.10.20.50.3-0.30.30.20.30.30.30.3-0.30.1-0.30.20.20.30.3-0.50.5-0.1
Latency to leave start box in cocaine runway0.40.51.50.20.8-0.70.70.40.60.60.50.9-0.50.8-0.61.20.80.60.9-0.80.8-0.5
Latency to leave start box in cocaine runway, F0.20.20.50.60.5-0.40.40.40.40.40.40.3-0.40.5-0.50.40.30.40.6-0.70.7-0.3
Latency to leave start box in cocaine runway, M0.40.42.7-0.30.6-0.60.60.10.40.30.21.0-0.10.8-0.31.60.90.50.7-0.40.4-0.4
Std. dev. time between licks in bursts0.61.22.0-1.4-1.21.2-1.1-1.1-1.1-1.0-1.0-1.30.9-1.01.0-1.4-0.9-1.3-0.81.0-1.00.5
Total sessions with >9 infusions0.40.61.71.30.7-0.70.70.90.71.00.9-0.1-0.90.6-0.70.10.60.50.4-0.50.5-1.0
Short access day 1 total inactive lever presses1.02.03.9-2.0-1.41.6-1.7-1.3-1.3-1.4-1.4-1.41.3-1.71.2-1.6-1.4-1.1-1.21.1-1.10.9
Short access day 10 total inactive lever presses0.21.74.7-2.2-0.81.6-1.5-1.6-1.5-1.6-1.6-0.81.5-1.31.2-0.7-1.4-0.7-0.60.6-0.61.3
Short access day 1 total infusions0.00.10.80.90.2-0.00.20.30.10.30.3-0.5-0.30.1-0.2-0.5-0.10.10.1-0.10.1-0.3
Short access day 10 total infusions0.50.81.50.70.9-0.90.80.90.91.21.00.5-0.90.9-0.90.60.90.80.6-0.80.8-1.1
Short access total infusions0.10.20.90.90.3-0.40.40.50.40.60.6-0.2-0.50.3-0.4-0.10.30.2-0.1-0.10.1-0.5
Short access day 1 locomotion0.81.33.41.81.3-1.21.21.41.21.41.30.6-1.31.1-1.10.71.01.10.6-0.70.7-1.2
Short access day 10 total locomotion0.73.06.4-0.7-1.91.9-1.9-1.7-1.7-1.6-1.6-2.41.5-2.11.5-2.5-1.8-1.5-1.71.5-1.51.0
Short access total locomotion0.10.10.70.4-0.10.2-0.20.1-0.00.10.1-0.8-0.2-0.3-0.1-0.80.10.2-0.10.0-0.0-0.8
One hour access (0.3 mA shock)1.21.43.6-0.7-1.50.8-0.9-1.1-1.0-1.0-1.1-0.71.2-0.91.3-0.5-1.1-1.5-1.61.4-1.41.9
Compulsive drug intake0.60.81.80.0-1.10.6-1.0-0.8-0.7-1.0-0.9-0.60.9-1.10.9-0.4-0.9-1.1-1.21.0-1.01.3
One hour access (shock baseline)0.10.20.5-0.50.2-0.50.60.40.40.60.40.5-0.40.7-0.40.50.70.40.4-0.40.4-0.6
Social response proportion2.12.76.20.11.6-1.71.71.21.31.01.12.2-1.02.2-1.42.52.01.62.0-1.81.8-1.4
Social responses4.66.19.51.62.4-2.82.72.42.42.32.32.9-2.22.9-2.23.12.82.22.5-2.42.3-2.1
Social time0.20.31.2-0.40.5-0.70.50.50.50.10.30.9-0.10.8-0.41.10.70.20.4-0.30.4-0.2
Soleus weight0.20.71.40.10.9-0.90.90.70.80.60.81.1-0.80.9-0.81.20.90.80.9-0.70.7-0.5
Bone: stiffness0.40.71.1-0.9-0.90.8-0.8-0.8-0.9-0.8-0.8-0.80.8-0.90.9-0.3-0.5-0.9-0.60.9-1.10.5
Tibialis anterior weight0.10.41.4-0.90.4-0.70.70.30.40.30.41.1-0.20.9-0.41.20.70.40.8-0.30.4-0.1
Time to tail flick, vehicle, before self-admin0.20.20.70.3-0.20.3-0.1-0.1-0.30.1-0.0-0.40.1-0.50.4-0.6-0.4-0.6-0.70.8-0.80.2
Time to tail flick, vehicle, after self-admin0.61.32.5-0.4-1.01.0-1.0-0.9-1.0-0.9-0.9-1.21.0-1.11.2-0.8-1.2-1.6-1.41.5-1.51.3
Time to tail flick, test, before self-admin0.30.30.70.50.6-0.60.70.70.60.30.80.4-0.70.7-0.50.50.70.50.4-0.40.4-0.7
Time to tail flick, test, after self-admin0.10.10.4-0.3-0.60.3-0.2-0.2-0.3-0.3-0.2-0.40.3-0.20.4-0.6-0.1-0.3-0.50.6-0.60.0
Delta time to tail flick, vehicle, before/after SA2.02.23.1-1.5-1.71.4-1.5-1.6-1.5-1.7-1.6-1.31.6-1.31.5-1.0-1.3-1.6-1.31.4-1.41.6
Delta time to tail flick, test, before/after SA0.00.10.2-0.2-0.30.2-0.2-0.1-0.2-0.0-0.2-0.20.2-0.20.2-0.5-0.2-0.2-0.20.4-0.4-0.0
Tibia length0.10.31.40.3-0.40.7-0.9-0.2-0.4-0.5-0.3-1.20.3-0.90.3-0.5-0.2-0.5-0.40.3-0.5-0.8
Ambulatory time before self-admin0.30.91.5-0.2-0.91.1-1.1-0.8-1.0-1.1-0.9-1.21.0-0.80.9-0.9-0.9-1.1-0.91.0-1.00.4
Ambulatory time after self-admin0.10.10.80.90.4-0.30.30.50.30.20.30.4-0.30.4-0.30.50.30.20.3-0.10.0-0.2
Bone: tissue strength0.60.61.0-0.4-0.71.0-0.9-0.7-0.7-0.8-0.8-1.00.7-0.90.8-0.8-0.8-0.5-0.90.7-0.80.5
Total heroin consumption0.10.21.11.1-0.10.4-0.2-0.1-0.3-0.1-0.1-0.70.2-0.10.2-0.7-0.6-0.0-0.30.3-0.30.4
Bone: trabecular number1.73.34.2-1.7-1.91.7-1.7-2.0-1.9-2.1-2.0-1.72.0-1.51.9-1.3-1.7-1.8-1.81.8-1.91.9
Bone: trabecular spacing3.04.46.31.72.0-2.12.22.12.22.12.31.8-2.22.1-2.11.62.32.12.2-2.02.1-2.5
Bone: trabecular thickness0.00.00.5-0.10.1-0.1-0.00.1-0.1-0.1-0.10.10.20.00.00.3-0.2-0.2-0.20.2-0.10.7
Bone: trabecular tissue density0.20.42.00.6-0.20.5-0.4-0.4-0.3-0.2-0.4-0.30.2-1.00.3-0.3-1.1-0.4-0.80.3-0.41.4
Water consumed over 24 hours0.40.81.80.70.7-1.01.01.20.80.80.81.0-0.71.3-0.91.01.00.80.8-0.70.7-0.6
Number of responses in last shaping day1.01.31.81.21.0-1.11.11.21.11.21.20.9-1.31.1-1.20.81.21.21.2-1.11.1-1.4