Hub : Genes

LOC134485980

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	intron excision ratio	chr2_229434325_229435123	0.15	0.07	0.0e+00	0.15	0.16	0.15	0.16	3.1e-16	2.5e-17	3.5e-16	3.4e-17
2	Liver	intron excision ratio	chr2_229434325_229435405	0.15	0.07	0.0e+00	0.15	0.16	0.15	0.16	2.2e-16	2.3e-17	2.7e-16	2.8e-17
3	Liver	gene expression	LOC134485980	0.36	0.11	0.0e+00	0.19	0.3	0.3	0.3	2.4e-20	2.9e-33	1.4e-33	1.6e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.1	0.2	0.7	0.0	-0.0	-0.8
Area under the delay curve	0.1	0.2	0.2	-0.4	0.4	-0.4
BMI with tail	1.3	4.6	6.9	2.6	-2.6	0.1
BMI without tail	0.8	4.1	6.1	2.5	-2.5	0.3
Body weight	1.5	6.7	10.0	3.2	-3.1	0.5
Weight adjusted by age	0.0	0.1	0.3	0.0	-0.0	-0.5
Bone surface	0.0	0.1	0.1	-0.2	0.2	-0.4
Bone volume	0.0	0.1	0.1	-0.3	0.3	0.1
Breakpoint value in progressive ratio session	0.8	1.4	1.6	1.3	-1.3	-1.0
Number of licking bursts	0.4	1.1	1.5	1.2	-1.2	-0.6
Context. condit. distance diff. score	0.4	0.5	1.0	0.6	-0.6	-1.0
Locomotion velocity, session 1	0.2	0.2	0.6	0.2	-0.2	0.8
Locomotion distance, session 1	0.1	0.1	0.1	0.4	-0.4	0.3
Locomotion velocity, session 2	0.1	0.1	0.3	0.1	-0.1	-0.5
Locomotion distance, session 2	0.2	0.3	0.5	-0.5	0.5	0.7
Locomotion velocity, session 3	0.8	0.9	2.5	-0.3	0.3	1.6
Locomotion distance, session 3	0.0	0.0	0.0	-0.1	0.1	-0.0
Stereotopy head waving bouts, day 3	0.5	0.6	1.8	-0.1	0.1	1.4
Stereotopy head waving duration, day 3	0.6	0.7	1.7	0.5	-0.4	1.3
Locomotion velocity, session 7	0.6	0.7	1.0	1.0	-1.0	-0.2
Locomotion distance, session 7	1.1	1.4	1.6	1.1	-1.1	-1.3
Stereotopy head waving bouts, day 7	3.3	3.8	5.3	-1.7	1.8	2.3
Stereotopy head waving duration, day 7	4.2	5.2	7.2	-2.0	2.1	2.7
Locomotion velocity, session 8	0.0	0.0	0.0	-0.0	0.0	-0.1
Locomotion distance, session 8	0.3	0.4	0.5	0.7	-0.7	-0.5
Degree of sensitization distance	1.7	1.9	2.1	1.3	-1.3	-1.5
Degree of sensitization stereotypy	3.0	3.4	4.1	-1.7	1.7	2.0
Conditioned locomotion	1.4	1.6	2.0	-1.4	1.4	0.9
Cocaine response after cond. corrected	0.0	0.0	0.1	-0.1	0.1	0.3
Cocaine response after cond. not corrected	0.0	0.1	0.2	0.0	-0.1	-0.4
Cocaine response before conditioning	0.2	0.2	0.5	0.3	-0.3	-0.7
Saline control response	1.8	2.4	3.5	-1.4	1.4	1.9
Bone: connectivity density	0.5	0.8	2.2	-0.2	0.2	-1.5
Bone: cortical apparent density	0.2	0.4	0.5	0.7	-0.7	-0.3
Bone: cortical area	1.1	1.8	2.6	1.6	-1.6	0.3
Bone: cortical porosity	0.3	0.3	0.9	0.0	-0.0	1.0
Bone: cortical porosity	0.4	0.4	1.2	0.3	-0.2	1.1
Bone: cortical thickness	1.3	2.2	3.3	1.8	-1.8	0.1
Bone: cortical thickness	1.0	1.2	1.8	1.3	-1.3	-0.0
Bone: cortical tissue density	0.2	0.4	0.5	0.7	-0.7	-0.3
Condit. Reinf. active minus inactive responses	0.6	0.7	1.0	1.0	-1.0	0.3
Condit. Reinf. active-inactive response ratio	2.6	2.8	4.1	2.0	-2.0	0.3
Condit. Reinf. active responses	0.1	0.1	0.3	-0.1	0.1	0.5
Condit. Reinf. inactive responses	1.8	2.3	3.3	-1.8	1.8	0.7
Incentive salience index mean	0.5	0.7	1.0	1.0	-1.0	0.1
Condit. Reinf. lever presses	0.0	0.1	0.2	0.0	-0.0	0.4
Condit. Reinf. active minus inactive responses	0.1	0.1	0.1	0.3	-0.3	0.3
Condit. Reinf. active-inactive response ratio	0.3	0.4	0.6	0.8	-0.8	-0.1
Condit. Reinf. active responses	0.2	0.3	0.5	0.7	-0.7	-0.1
Condit. Reinf. inactive responses	0.1	0.1	0.2	0.5	-0.5	0.0
Condit. Reinf. lever presses	0.6	0.9	1.2	1.1	-1.1	-0.7
Condit. Reinf. lever reinforcers received	0.2	0.3	0.5	0.7	-0.7	-0.2
Conditioned reinforcement - actives	1.0	4.0	4.2	-2.0	2.0	2.0
Conditioned reinforcement - inactives	0.5	1.4	1.7	-1.3	1.3	0.9
Conditioned locomotion	1.9	2.8	4.2	-2.1	2.0	0.3
Patch foraging indifference point 0 sec	0.2	0.4	0.7	-0.5	0.5	-0.8
Patch foraging indifference point AUC	0.3	0.7	1.0	1.0	-1.0	-0.4
Delay disc. indifference point, 0s delay	0.9	1.1	1.6	-1.3	1.3	-0.1
Delay disc. indifference point, 16s delay	0.0	0.0	0.0	0.2	-0.2	-0.2
Delay disc. indifference point, 2s delay	1.9	2.1	3.2	-1.8	1.8	0.3
Delay disc. indifference point, 24s delay	0.2	0.3	0.4	-0.7	0.6	-0.3
Delay disc. indifference point, 4s delay	0.6	0.6	1.7	0.3	-0.3	-1.3
Delay disc. indifference point, 8s delay	0.2	0.3	0.4	-0.6	0.6	0.5
Indifference point function ln k	0.0	0.0	0.0	0.2	-0.2	0.1
Indifference point function log k	0.0	0.0	0.0	0.2	-0.2	0.1
Patch foraging total patch changes 0 sec	0.1	0.4	0.8	-0.3	0.3	-0.9
Patch foraging total patch changes 12 sec	0.6	0.8	1.0	0.9	-0.9	-1.0
Patch foraging total patch changes 18 sec	0.2	0.5	1.1	0.4	-0.4	-1.1
Patch foraging total patch changes 24 sec	0.0	0.1	0.2	-0.2	0.2	0.4
Patch foraging total patch changes 6 sec	1.7	2.8	4.2	1.5	-1.5	-2.1
Patch foraging time to switch 0 sec	0.3	1.2	1.7	-1.3	1.3	0.5
Patch foraging water rate 0 sec	0.2	0.9	1.2	1.1	-1.1	-0.5
Patch foraging water rate 12 sec	0.3	1.2	1.7	1.3	-1.3	0.6
Patch foraging water rate 18 sec	1.4	3.2	4.2	2.1	-2.1	-1.0
Patch foraging water rate 24 sec	1.5	2.1	2.9	1.7	-1.7	-0.7
Patch foraging water rate 6 sec	4.0	5.9	8.7	2.9	-2.9	-0.6
Seeking ratio, delayed vs. immediate footshock	0.9	1.2	1.4	-1.2	1.2	-1.0
Distance traveled before self-admin	0.4	0.9	1.2	-0.8	0.8	1.1
Distance traveled after self-admin	0.0	0.0	0.0	-0.1	0.1	-0.1
Extensor digitorum longus weight	1.6	6.5	9.2	2.3	-2.3	3.0
Bone: elastic displacement	0.4	0.5	0.6	0.8	-0.8	0.5
Bone: elastic work	1.9	2.5	3.8	1.9	-1.9	0.0
Bone: endosteal estimation	0.0	0.0	0.1	-0.0	0.0	0.3
Bone: endosteal perimeter	0.2	0.4	1.2	-0.2	0.2	1.1
Epididymis fat weight	0.2	1.1	1.6	1.2	-1.2	0.4
Delta time in closed arm before/after self-admin	0.4	0.4	0.8	-0.4	0.4	0.9
Delta time in open arm before/after self-admin	3.1	3.7	5.1	-1.7	1.7	2.3
Diff in mean of infusions in LGA sessions	1.9	3.4	5.7	1.5	-1.5	-2.4
Delay discount exponential model param	0.1	0.2	0.3	0.3	-0.3	0.5
Extinction: sum of active levers before priming	1.4	2.2	2.7	1.7	-1.7	-1.0
Active lever presses in extinction session 6	0.6	0.6	1.7	-0.1	0.1	-1.3
Bone: final force	0.5	0.8	1.2	1.1	-1.1	-0.1
Bone: final moment	0.6	1.0	1.4	1.2	-1.2	-0.3
Food consumed during 24 hour testing period	0.7	1.4	2.1	1.5	-1.5	-0.3
Glucose	2.3	3.6	5.0	2.2	-2.2	-0.9
Heart weight	0.4	0.6	0.6	0.7	-0.7	0.8
Delay discount hyperbolic model param	0.2	0.2	0.3	0.5	-0.5	0.5
Intermittent access intake day 1-15 change	0.1	0.4	0.6	-0.8	0.8	-0.1
Intermittent access intake escalation	0.1	0.5	0.5	-0.7	0.7	-0.6
Intermittent access intake escalation 2	0.1	0.2	0.7	-0.0	0.0	-0.8
Intermitt. access day 1 inactive lever presses	0.0	0.2	0.2	0.5	-0.5	-0.2
Intermitt. access day 15 inactive lever presses	0.0	0.2	0.5	0.3	-0.3	0.7
Intermitt. access escalation Index	0.2	0.7	1.5	-0.5	0.5	1.2
Intermittent access day 1 total infusions	0.5	1.4	2.1	1.5	-1.5	-0.2
Intermittent access day 15 total infusions	0.4	0.9	1.0	1.0	-1.0	-0.8
Intermittent access terminal intake (last 3 days)	0.6	1.0	1.3	1.2	-1.2	-0.5
Intermittent access total infusions	1.2	1.4	2.0	1.4	-1.4	-0.4
Intermittent access day 1 locomotion	0.3	0.5	0.8	0.9	-0.9	0.0
Intermittent access day 15 total locomotion	0.0	0.1	0.3	-0.3	0.3	-0.6
Intermittent access total locomotion	0.2	0.2	0.3	0.6	-0.6	-0.4
Intermittent access standard deviation	0.1	0.3	0.4	0.7	-0.6	-0.3
Left kidney weight	0.4	2.8	4.2	2.0	-2.0	0.4
Right kidney weight	0.3	2.1	2.8	1.7	-1.7	0.7
Cocaine induced anxiety	0.0	0.0	0.0	-0.1	0.1	-0.2
Post-drug Anxiety	0.2	0.2	0.4	-0.6	0.6	-0.1
Baseline Anxiety	0.0	0.1	0.1	0.3	-0.3	0.2
Tail length	0.0	0.3	0.7	0.3	-0.2	0.8
Length with tail	0.3	1.4	2.1	1.4	-1.4	0.5
Length without tail	0.1	0.3	0.5	0.7	-0.7	0.2
Times rat made contact with spout	2.3	2.7	3.6	1.5	-1.5	-1.9
Lifetime Intake	0.6	0.7	1.1	1.0	-1.0	-0.0
Liver weight, left	0.1	0.2	0.5	-0.1	0.1	0.7
Liver weight, right	0.2	0.3	0.5	0.7	-0.7	-0.0
Locomotor activity	0.4	0.5	0.8	0.7	-0.7	-0.9
Locomotor testing distance	0.3	0.8	0.8	0.9	-0.9	-0.9
Locomotor testing rearing	2.5	9.1	9.2	3.0	-3.0	-3.0
Locomotion in novel chamber	1.2	1.6	3.4	-0.9	0.9	-1.8
Locomotion in novel chamber post-restriction	0.0	0.0	0.0	-0.1	0.1	-0.2
Fecal boli incidents, locomotor time 1	0.3	0.9	0.9	-1.0	1.0	0.9
Change in fecal boli incidents, locomotor task	2.4	2.5	2.9	1.7	-1.7	-1.3
Time >=10cm from walls, locomotor time 1	2.0	2.5	4.9	1.1	-1.1	-2.2
Bouts of movement, locomotor time 1	0.7	0.9	1.1	0.9	-0.9	-1.0
Total resting periods, locomotor time 1	0.5	0.6	0.6	0.8	-0.8	-0.8
Rest time, locomotor task time 1	0.6	1.0	1.4	-0.9	0.9	1.2
Distance moved, locomotor task time 1	0.3	0.8	0.9	0.9	-0.9	-0.9
Vertical activity count, locomotor time 1	0.1	0.4	0.8	0.5	-0.5	-0.9
Time >=10cm from walls, locomotor time 2	0.1	0.4	0.9	0.3	-0.3	1.0
Bouts of movement, locomotor time 2	0.1	0.5	0.5	-0.7	0.7	-0.6
Total resting periods, locomotor time 2	0.1	0.5	0.5	-0.7	0.7	-0.7
Rest time, locomotor task time 2	0.1	0.2	0.4	-0.6	0.6	-0.0
Distance moved, locomotor task time 2	0.1	0.1	0.1	-0.3	0.3	0.2
Vertical activity count, locomotor time 2	0.0	0.1	0.1	-0.3	0.3	0.2
Light reinforcement 1	0.3	1.5	2.2	1.5	-1.5	-0.2
Light reinforcement 2	0.0	0.1	0.1	0.3	-0.3	-0.0
Bone: marrow area	0.0	0.0	0.0	-0.0	0.0	0.2
Bone: maximum diameter	0.1	0.3	0.4	0.6	-0.6	0.1
Bone: maximum force	0.3	0.5	0.8	0.9	-0.9	0.1
Bone: maximum moment	0.4	0.7	1.1	1.0	-1.0	-0.2
Mean time between licks in bursts	0.0	0.3	0.3	0.5	-0.5	-0.5
Mean num. licks in bursts	0.0	0.1	0.4	-0.0	0.0	-0.6
Cd content in liver	1.1	1.2	1.6	1.3	-1.3	-0.6
Co content in liver	0.8	1.0	1.3	0.9	-0.9	1.1
Cu content in liver	1.0	1.2	3.3	0.3	-0.3	-1.8
Fe content in liver	2.8	3.5	4.4	-2.1	2.1	1.3
K content in liver	0.5	0.5	1.3	-0.2	0.1	-1.1
Mg content in liver	0.5	0.5	1.3	0.3	-0.3	-1.1
Mn content in liver	1.0	1.1	1.1	1.0	-1.1	-1.1
Na content in liver	0.1	0.1	0.3	-0.2	0.2	-0.6
Rb content in liver	0.6	0.7	0.7	-0.8	0.8	0.9
Se content in liver	0.3	0.3	0.5	-0.7	0.7	0.3
Sr content in liver	0.1	0.1	0.2	0.4	-0.4	-0.3
Zn content in liver	7.8	9.1	27.2	0.2	-0.2	-5.2
Bone: minimum diameter	1.0	1.9	2.4	1.5	-1.5	0.9
Time in familiar zone, hab. session 1	0.8	0.9	1.0	-0.9	0.9	1.0
Time in novel zone, hab. session 1	0.0	0.0	0.0	0.1	-0.1	-0.2
Total zone transitions, hab. session 1	0.9	1.3	2.9	-0.7	0.7	1.7
Total locomotion distance, hab. session 1	0.2	0.2	0.3	-0.5	0.5	0.5
Locomotion velocity, hab. session 1	0.0	0.0	0.0	0.1	-0.1	0.1
Time in familiar zone, hab. session 2	0.5	0.6	0.8	0.9	-0.9	-0.5
Time in novel zone, hab. session 2	0.5	0.6	0.8	-0.9	0.9	0.2
Total zone transitions, hab. session 2	0.2	0.2	0.7	-0.1	0.1	0.8
Total locomotion distance, hab. session 2	0.4	0.5	0.6	0.8	-0.8	-0.4
Locomotion velocity, hab. session 2	0.2	0.3	0.3	0.6	-0.6	-0.4
Novel to familiar place preference ratio	0.4	0.5	0.8	0.6	-0.6	-0.9
Novelty place preference	0.7	0.9	1.3	0.9	-0.9	-1.1
Time in novel zone, NPP test	0.9	1.0	1.4	0.9	-0.9	-1.2
Total zone transitions, NPP test	0.3	0.5	0.6	0.8	-0.8	0.5
Total locomotion distance, NPP test	0.7	1.0	1.3	1.1	-1.1	-0.7
Locomotion velocity, NPP test	1.1	1.6	2.0	1.4	-1.4	-0.9
Intraocular pressure	0.8	1.4	1.4	-1.2	1.2	1.2
Delta distance traveled before/after self-admin	0.6	0.7	1.0	0.7	-0.7	-1.0
Delta ambulatory time before/after self-admin	0.7	1.2	1.6	1.0	-1.0	-1.3
Parametrial fat weight	0.1	0.2	0.4	0.2	-0.2	-0.6
Pavlov. Cond. lever latency	0.4	0.5	0.7	0.9	-0.9	0.3
Pavlov. Cond. magazine entry latency	0.5	0.6	0.9	-0.7	0.7	0.9
Pavlov. Cond. change in total contacts	0.4	0.4	0.6	-0.8	0.8	0.0
Pavlov. Cond. index score	0.1	0.2	0.2	-0.5	0.5	-0.2
Pavlov. Cond. latency score	0.2	0.3	0.4	-0.6	0.6	-0.3
Pavlov. Cond. lever contacts	0.1	0.1	0.2	-0.3	0.3	-0.4
Pavlov. Cond. magazine entry number	0.3	0.3	0.7	0.4	-0.4	-0.8
Pavlov. Cond. intertrial magazine entries	0.0	0.1	0.1	-0.3	0.3	-0.0
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	-0.2	0.2	-0.6
Pavlov. Cond. response bias	0.4	0.5	0.5	-0.7	0.7	0.7
Pavlov. Cond. lever latency	0.5	0.7	1.1	-1.0	1.0	-0.1
Pavlov. Cond. magazine entry latency	0.2	0.2	0.3	-0.6	0.6	0.3
Pavlov. Cond. change in total contacts	0.2	0.5	0.5	0.7	-0.7	-0.6
Pavlov. Cond. index score	0.0	0.0	0.0	-0.1	0.1	0.1
Pavlov. Cond. latency score	0.0	0.0	0.1	-0.2	0.2	-0.1
Pavlov. Cond. lever contacts	0.5	0.7	1.0	1.0	-1.0	0.3
Pavlov. Cond. magazine entry number	0.1	0.2	0.2	0.5	-0.5	-0.3
Pavlov. Cond. intertrial magazine entries	0.5	1.1	1.4	1.2	-1.2	-0.8
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.0	-0.1	0.1	0.1
Pavlov. Cond. response bias	0.3	0.5	0.5	0.7	-0.7	0.7
Time in closed arm before self-admin	0.0	0.1	0.2	0.1	-0.1	-0.5
Time in closed arm after self-admin	0.6	0.7	1.6	0.5	-0.5	-1.3
Time in open arm before self-admin	2.2	2.7	3.2	1.8	-1.8	-1.3
Time in open arm after self-admin	1.0	1.1	2.2	-0.8	0.8	1.5
Bone: periosteal estimation	0.3	0.8	1.1	1.0	-1.0	0.5
Bone: periosteal perimeter	0.3	0.6	1.4	0.4	-0.4	1.2
Bone: post-yield work	0.7	1.2	1.8	-1.3	1.3	0.3
Progressive ratio test 1 active lever presses	0.7	1.1	1.7	1.3	-1.3	0.4
Progressive ratio test 1 breakpoint	0.7	1.3	1.9	1.4	-1.4	0.2
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.2	0.4	-0.4	-0.0
Progressive ratio test 2 active lever presses	0.5	0.8	0.9	0.9	-0.9	0.7
Progressive ratio test 2 breakpoint	0.6	0.8	1.1	1.0	-1.0	0.5
Progressive ratio test 2 inactive lever presses	0.3	0.8	1.7	-0.6	0.6	1.3
Incentive Sensitization - Responses	0.5	1.3	1.4	-1.2	1.2	1.0
Incentive Sensitization - Breakpoint	0.4	0.9	1.0	-1.0	1.0	0.9
Sum of active levers in priming session hrs 5-6	2.8	2.7	4.3	1.4	-1.4	-2.1
Progressive ratio	0.0	0.1	0.3	0.0	-0.0	0.5
Food seeking constrained by brief footshock	1.8	2.3	3.3	1.8	-1.8	-0.5
Seeking ratio, punishment vs. effort	0.5	1.2	1.2	1.1	-1.1	-1.1
Retroperitoneal fat weight	0.4	1.8	2.7	1.6	-1.6	-0.2
Reaction time number correct	0.2	0.6	0.7	0.9	-0.9	-0.5
Reaction time mean minus median	0.3	1.9	2.3	-1.5	1.5	1.1
Reaction time mean minus median AUC	0.2	1.0	1.3	-1.2	1.1	0.7
Reaction time num false alarms	2.4	4.1	4.3	-2.1	2.1	1.9
Reaction time num false alarms AUC	2.1	4.8	5.9	-2.1	2.1	2.4
Reaction time trials correct on left	0.2	0.6	0.7	0.9	-0.9	-0.5
Reaction time trials on left	0.1	0.4	0.6	0.7	-0.7	-0.5
Reaction time mean	0.1	0.3	0.3	-0.6	0.6	0.5
Reaction time mean AUC	0.1	0.2	0.3	-0.4	0.4	0.6
Median of all reaction times	0.0	0.0	0.0	0.1	-0.1	0.2
Reaction time omissions	2.1	3.4	4.8	-2.2	2.2	0.9
Reaction time false alarm rate	3.0	4.2	4.3	-2.1	2.1	2.0
Reaction time premature initiation rate	0.5	0.7	2.1	0.1	-0.1	1.5
Reaction time premature initiations	0.3	0.8	2.3	0.3	-0.3	1.5
Std. dev. reaction times	0.7	2.3	3.0	-1.7	1.7	0.9
Reaction time trials completed	0.1	0.4	0.6	0.7	-0.7	-0.5
Reaction time trials AUC	0.1	0.5	0.7	0.8	-0.8	-0.4
Run reversals in cocaine runway, females	0.9	1.0	1.5	0.8	-0.8	-1.2
Run reversals in cocaine runway, males	1.1	1.2	1.4	1.2	-1.2	-1.0
Latency to leave start box in cocaine runway	0.5	0.6	1.8	0.3	-0.3	-1.3
Latency to leave start box in cocaine runway, F	0.0	0.1	0.1	-0.2	0.2	-0.3
Latency to leave start box in cocaine runway, M	1.8	1.7	4.1	0.7	-0.7	-2.0
Std. dev. time between licks in bursts	0.3	0.5	1.1	0.5	-0.5	-1.1
Total sessions with >9 infusions	0.1	0.1	0.2	-0.0	0.0	0.5
Short access day 1 total inactive lever presses	0.2	0.3	0.4	0.6	-0.6	-0.4
Short access day 10 total inactive lever presses	0.2	1.6	2.4	-1.5	1.5	0.1
Short access day 1 total infusions	0.4	0.7	1.0	-0.8	0.8	1.0
Short access day 10 total infusions	0.2	0.3	0.4	0.6	-0.6	-0.2
Short access total infusions	0.1	0.1	0.2	0.5	-0.5	0.1
Short access day 1 locomotion	0.0	0.0	0.1	-0.1	0.1	0.3
Short access day 10 total locomotion	0.1	0.5	0.8	0.6	-0.6	-0.9
Short access total locomotion	0.2	0.3	0.7	0.3	-0.3	-0.8
One hour access (0.3 mA shock)	0.4	0.5	0.5	0.7	-0.7	-0.6
Compulsive drug intake	0.3	0.4	0.4	0.7	-0.7	-0.6
One hour access (shock baseline)	0.1	0.2	0.3	0.5	-0.5	-0.2
Social response proportion	0.9	1.2	1.6	-1.3	1.3	0.6
Social responses	0.6	0.8	1.2	0.8	-0.8	-1.1
Social time	0.6	1.0	1.5	-1.2	1.2	-0.0
Soleus weight	0.3	0.8	2.0	0.5	-0.5	1.4
Bone: stiffness	0.5	0.9	1.3	1.1	-1.1	-0.2
Tibialis anterior weight	2.2	7.6	8.8	3.0	-2.9	2.3
Time to tail flick, vehicle, before self-admin	1.3	1.6	2.1	-1.4	1.4	0.9
Time to tail flick, vehicle, after self-admin	1.7	3.4	3.7	-1.9	1.9	1.7
Time to tail flick, test, before self-admin	0.7	0.8	1.1	-1.1	1.1	0.2
Time to tail flick, test, after self-admin	0.3	0.3	0.3	-0.5	0.5	0.5
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.2	-0.1	0.1	0.5
Delta time to tail flick, test, before/after SA	0.2	0.3	0.4	0.6	-0.6	0.2
Tibia length	0.3	0.9	1.2	1.1	-1.1	0.6
Ambulatory time before self-admin	0.4	1.1	1.5	-1.0	1.0	1.2
Ambulatory time after self-admin	0.5	0.7	1.0	-1.0	1.0	0.5
Bone: tissue strength	0.9	0.9	1.3	1.1	-1.1	-0.4
Total heroin consumption	0.1	0.2	0.2	0.4	-0.4	-0.4
Bone: trabecular number	1.0	1.8	2.5	-1.6	1.6	0.5
Bone: trabecular spacing	2.1	3.0	3.1	1.7	-1.7	-1.8
Bone: trabecular thickness	0.3	0.4	0.6	-0.5	0.5	0.8
Bone: trabecular tissue density	0.2	0.3	0.6	-0.4	0.4	0.8
Water consumed over 24 hours	0.3	0.5	0.7	0.8	-0.8	-0.4
Number of responses in last shaping day	1.8	2.3	5.0	-1.0	1.0	2.2