Hub : Genes

LOC134485978

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	IC	gene expression	LOC134485978	0.17	0.07	4.5e-05	0.03	0.09	0.1	0.08	1.8e-02	2.1e-04	8.0e-05	3.2e-04
2	PL	gene expression	LOC134485978	0.09	0.05	1.3e-06	0.07	0.06	0.06	0.06	7.2e-08	3.4e-07	4.5e-07	2.2e-07
3	Brain	gene expression	LOC134485978	0.07	0.04	1.4e-05	0.04	0.05	0.04	0.05	6.4e-05	1.1e-05	7.1e-05	2.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.2	0.3	0.6	-0.1	0.8	0.6
Area under the delay curve	0.0	0.0	0.1	-0.1	-0.2	0.3
BMI with tail	0.1	0.3	0.7	0.4	0.4	-0.9
BMI without tail	0.4	2.2	2.7	1.3	1.5	-1.6
Body weight	0.2	0.9	1.9	0.6	0.7	-1.4
Weight adjusted by age	0.0	0.1	0.1	0.0	0.4	-0.1
Bone surface	0.1	0.3	0.7	0.3	0.9	0.1
Bone volume	0.5	1.0	2.1	0.8	1.4	-0.4
Breakpoint value in progressive ratio session	0.7	1.3	2.0	-1.4	-0.8	1.1
Number of licking bursts	1.4	4.2	5.4	-2.3	-2.3	1.5
Context. condit. distance diff. score	2.6	3.2	4.6	-2.1	-1.3	1.8
Locomotion velocity, session 1	0.5	0.6	1.6	0.4	-0.2	-1.3
Locomotion distance, session 1	1.2	1.5	3.0	-1.2	-1.7	-0.0
Locomotion velocity, session 2	0.1	0.1	0.1	-0.3	-0.4	0.1
Locomotion distance, session 2	0.7	1.0	2.4	-0.6	-1.6	-0.6
Locomotion velocity, session 3	0.6	0.7	1.4	-0.4	-1.2	-0.7
Locomotion distance, session 3	0.6	0.7	0.9	-1.0	-0.9	0.4
Stereotopy head waving bouts, day 3	0.8	0.9	1.8	0.9	0.5	-1.3
Stereotopy head waving duration, day 3	0.4	0.5	1.1	0.5	0.2	-1.1
Locomotion velocity, session 7	0.2	0.3	0.5	-0.7	-0.5	0.2
Locomotion distance, session 7	3.0	3.8	4.5	-2.1	-2.1	1.6
Stereotopy head waving bouts, day 7	3.6	4.2	4.8	2.1	1.9	-2.2
Stereotopy head waving duration, day 7	3.4	4.2	5.5	2.0	1.7	-2.3
Locomotion velocity, session 8	0.2	0.2	0.5	-0.7	-0.2	0.2
Locomotion distance, session 8	3.1	4.5	6.5	-2.5	-2.4	1.1
Degree of sensitization distance	1.3	1.4	2.0	-1.2	-0.9	1.4
Degree of sensitization stereotypy	4.4	4.9	5.1	2.3	2.3	-2.1
Conditioned locomotion	3.7	4.4	6.0	2.1	2.5	-1.6
Cocaine response after cond. corrected	0.6	0.9	1.2	1.1	1.0	-0.6
Cocaine response after cond. not corrected	0.9	1.3	1.8	1.4	1.3	-0.5
Cocaine response before conditioning	0.0	0.0	0.1	0.2	0.2	0.0
Saline control response	0.7	0.9	2.0	0.9	0.2	-1.4
Bone: connectivity density	0.9	1.4	2.6	-1.2	-0.5	1.6
Bone: cortical apparent density	0.1	0.1	0.2	-0.5	-0.1	0.3
Bone: cortical area	0.5	0.8	1.4	0.8	1.2	-0.7
Bone: cortical porosity	0.8	0.9	1.4	1.1	0.5	-1.2
Bone: cortical porosity	1.2	1.4	2.0	1.3	0.7	-1.4
Bone: cortical thickness	0.3	0.5	1.1	0.5	1.1	-0.3
Bone: cortical thickness	1.8	2.2	3.1	1.5	1.8	-1.1
Bone: cortical tissue density	0.1	0.1	0.3	-0.5	-0.2	0.3
Condit. Reinf. active minus inactive responses	0.5	0.5	0.8	-0.9	-0.9	-0.1
Condit. Reinf. active-inactive response ratio	0.6	0.7	1.2	-0.9	-1.1	-0.1
Condit. Reinf. active responses	0.2	0.2	0.5	-0.4	-0.7	-0.3
Condit. Reinf. inactive responses	0.6	0.8	1.0	1.0	0.8	-0.8
Incentive salience index mean	0.3	0.3	0.5	-0.7	-0.7	-0.0
Condit. Reinf. lever presses	0.0	0.0	0.1	-0.2	-0.1	-0.1
Condit. Reinf. active minus inactive responses	0.4	0.6	1.3	0.5	1.1	-0.4
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	-0.4	0.1	0.4
Condit. Reinf. active responses	0.8	1.1	2.3	0.8	1.5	-0.6
Condit. Reinf. inactive responses	0.5	0.8	1.0	0.7	1.0	-0.9
Condit. Reinf. lever presses	0.3	0.4	1.1	0.5	1.0	-0.0
Condit. Reinf. lever reinforcers received	0.7	1.0	2.2	0.8	1.5	-0.6
Conditioned reinforcement - actives	0.1	0.4	0.8	-0.6	-0.9	-0.2
Conditioned reinforcement - inactives	0.0	0.1	0.2	0.1	0.4	-0.3
Conditioned locomotion	0.5	0.7	1.0	-0.9	-0.5	1.0
Patch foraging indifference point 0 sec	1.0	2.7	3.0	-1.7	-1.6	1.6
Patch foraging indifference point AUC	0.1	0.2	0.3	-0.6	0.1	0.4
Delay disc. indifference point, 0s delay	0.5	0.5	0.8	-0.8	-0.4	0.9
Delay disc. indifference point, 16s delay	0.4	0.6	1.2	-0.6	-1.1	0.4
Delay disc. indifference point, 2s delay	0.1	0.1	0.3	0.6	0.3	-0.0
Delay disc. indifference point, 24s delay	0.1	0.1	0.3	0.1	0.5	0.2
Delay disc. indifference point, 4s delay	0.1	0.2	0.3	-0.3	0.1	0.6
Delay disc. indifference point, 8s delay	0.2	0.3	0.5	0.5	0.3	-0.7
Indifference point function ln k	0.2	0.6	1.7	-0.5	-1.3	0.1
Indifference point function log k	0.2	0.6	1.7	-0.5	-1.3	0.1
Patch foraging total patch changes 0 sec	1.0	2.9	3.3	-1.8	-1.7	1.6
Patch foraging total patch changes 12 sec	0.7	0.9	1.4	-1.2	-0.6	1.0
Patch foraging total patch changes 18 sec	1.3	3.0	3.8	-2.0	-1.6	1.6
Patch foraging total patch changes 24 sec	0.1	0.4	1.0	-1.0	-0.6	0.1
Patch foraging total patch changes 6 sec	2.7	4.5	5.9	-2.3	-1.6	2.4
Patch foraging time to switch 0 sec	0.1	0.2	0.4	0.5	0.6	-0.2
Patch foraging water rate 0 sec	0.1	0.4	0.5	-0.6	-0.7	0.5
Patch foraging water rate 12 sec	0.1	0.3	0.6	0.4	-0.4	-0.8
Patch foraging water rate 18 sec	0.3	0.7	1.0	-0.7	-1.0	0.8
Patch foraging water rate 24 sec	1.8	2.5	4.0	-1.6	-2.0	1.0
Patch foraging water rate 6 sec	0.3	0.5	1.2	-0.5	-1.1	-0.2
Seeking ratio, delayed vs. immediate footshock	0.4	0.5	0.9	0.7	0.9	0.4
Distance traveled before self-admin	0.2	0.4	0.5	0.6	0.7	-0.7
Distance traveled after self-admin	0.2	0.3	0.4	-0.6	-0.6	0.4
Extensor digitorum longus weight	3.9	15.7	19.9	3.9	3.5	-4.5
Bone: elastic displacement	0.2	0.2	0.3	0.5	0.2	-0.6
Bone: elastic work	0.2	0.2	0.3	0.4	0.5	-0.5
Bone: endosteal estimation	0.1	0.1	0.3	0.4	0.1	-0.5
Bone: endosteal perimeter	0.2	0.4	0.8	0.7	0.2	-0.9
Epididymis fat weight	0.1	0.3	0.6	-0.1	-0.8	-0.4
Delta time in closed arm before/after self-admin	0.3	0.2	0.5	-0.2	-0.4	-0.7
Delta time in open arm before/after self-admin	1.0	1.1	1.8	1.2	0.5	-1.4
Diff in mean of infusions in LGA sessions	1.9	3.3	4.1	-2.0	-1.4	2.0
Delay discount exponential model param	0.0	0.0	0.1	0.1	0.0	-0.3
Extinction: sum of active levers before priming	0.1	0.1	0.3	-0.0	0.5	0.4
Active lever presses in extinction session 6	4.2	4.2	5.0	-2.2	-1.9	2.0
Bone: final force	0.0	0.1	0.1	-0.4	-0.1	0.2
Bone: final moment	0.0	0.0	0.0	-0.2	-0.0	0.2
Food consumed during 24 hour testing period	0.1	0.2	0.5	0.3	0.3	-0.7
Glucose	0.0	0.0	0.0	-0.1	0.2	0.1
Heart weight	0.8	1.3	1.4	1.1	1.2	-1.1
Delay discount hyperbolic model param	0.0	0.0	0.1	0.0	0.0	-0.3
Intermittent access intake day 1-15 change	0.0	0.0	0.1	0.3	0.2	0.1
Intermittent access intake escalation	0.0	0.1	0.4	-0.1	0.0	0.6
Intermittent access intake escalation 2	0.1	0.2	0.6	-0.1	0.1	0.8
Intermitt. access day 1 inactive lever presses	0.0	0.1	0.1	0.2	0.2	-0.4
Intermitt. access day 15 inactive lever presses	0.3	1.5	1.8	1.1	1.2	-1.3
Intermitt. access escalation Index	0.6	1.8	2.1	1.5	1.2	-1.3
Intermittent access day 1 total infusions	0.1	0.2	0.3	-0.2	0.4	-0.5
Intermittent access day 15 total infusions	0.0	0.1	0.1	-0.3	0.1	0.3
Intermittent access terminal intake (last 3 days)	0.1	0.3	0.4	-0.7	-0.5	0.3
Intermittent access total infusions	0.1	0.2	0.4	-0.7	-0.3	0.1
Intermittent access day 1 locomotion	0.1	0.1	0.3	-0.5	0.1	-0.1
Intermittent access day 15 total locomotion	0.1	0.4	0.6	-0.8	-0.2	0.7
Intermittent access total locomotion	0.2	0.2	0.4	-0.6	0.3	0.3
Intermittent access standard deviation	0.0	0.1	0.1	-0.2	-0.2	0.3
Left kidney weight	0.2	1.3	1.6	1.0	1.3	-1.2
Right kidney weight	0.2	1.3	1.5	1.0	1.1	-1.2
Cocaine induced anxiety	0.3	0.8	1.2	-0.9	-1.1	0.7
Post-drug Anxiety	0.6	0.6	1.0	-0.7	-1.0	0.7
Baseline Anxiety	0.1	0.2	0.3	0.5	0.4	-0.5
Tail length	0.2	1.2	1.5	0.9	1.2	-1.1
Length with tail	0.1	0.6	0.9	0.7	0.6	-0.9
Length without tail	0.1	0.3	0.6	-0.5	-0.8	0.1
Times rat made contact with spout	0.4	0.5	0.9	-0.7	0.1	0.9
Lifetime Intake	0.1	0.2	0.4	-0.6	-0.4	-0.1
Liver weight, left	0.2	0.3	0.7	-0.5	-0.8	0.2
Liver weight, right	0.7	1.3	2.1	-1.5	-0.9	1.0
Locomotor activity	0.0	0.0	0.1	-0.2	0.1	0.3
Locomotor testing distance	0.1	0.2	0.3	0.4	0.6	-0.3
Locomotor testing rearing	0.2	0.6	1.1	-0.9	0.0	1.1
Locomotion in novel chamber	1.0	1.3	3.4	-0.5	0.5	1.9
Locomotion in novel chamber post-restriction	0.5	1.5	2.2	1.3	1.5	-0.7
Fecal boli incidents, locomotor time 1	0.2	0.6	1.3	0.4	1.1	-0.6
Change in fecal boli incidents, locomotor task	0.0	0.1	0.1	0.1	0.3	0.2
Time >=10cm from walls, locomotor time 1	2.1	2.6	4.8	-1.7	-0.5	2.2
Bouts of movement, locomotor time 1	0.3	0.3	0.8	-0.4	-0.1	0.9
Total resting periods, locomotor time 1	0.2	0.2	0.4	-0.5	-0.2	0.6
Rest time, locomotor task time 1	1.1	1.8	2.4	1.6	1.2	-1.3
Distance moved, locomotor task time 1	0.2	0.6	0.8	-0.8	-0.9	0.6
Vertical activity count, locomotor time 1	0.1	1.0	1.0	-1.0	-1.0	1.0
Time >=10cm from walls, locomotor time 2	0.2	0.6	1.3	0.8	0.0	-1.1
Bouts of movement, locomotor time 2	0.1	0.3	0.5	-0.3	-0.5	0.7
Total resting periods, locomotor time 2	0.1	0.3	0.5	-0.2	-0.5	0.7
Rest time, locomotor task time 2	0.7	1.3	1.9	1.3	1.4	-0.4
Distance moved, locomotor task time 2	0.8	1.1	2.8	-0.7	-1.7	0.2
Vertical activity count, locomotor time 2	0.1	0.2	0.6	-0.2	-0.8	0.1
Light reinforcement 1	0.0	0.2	0.3	-0.4	-0.5	-0.3
Light reinforcement 2	0.1	0.3	0.4	0.5	0.6	-0.5
Bone: marrow area	0.0	0.1	0.2	0.3	0.1	-0.4
Bone: maximum diameter	0.1	0.2	0.4	0.4	0.7	-0.3
Bone: maximum force	0.2	0.4	0.6	-0.8	-0.6	0.4
Bone: maximum moment	0.1	0.2	0.3	-0.6	-0.4	0.4
Mean time between licks in bursts	0.4	2.4	2.9	-1.6	-1.7	1.3
Mean num. licks in bursts	1.1	2.9	4.8	1.8	2.2	-0.8
Cd content in liver	1.0	1.1	1.5	-1.2	-0.9	0.9
Co content in liver	0.4	0.5	1.2	-0.1	-0.5	-1.1
Cu content in liver	3.0	3.5	4.3	-1.9	-1.6	2.1
Fe content in liver	0.4	0.5	0.8	0.7	0.9	-0.5
K content in liver	0.4	0.4	0.8	-0.5	0.2	0.9
Mg content in liver	1.0	1.1	1.6	-1.3	-0.7	1.1
Mn content in liver	0.3	0.3	0.8	0.3	0.9	0.2
Na content in liver	0.1	0.1	0.2	-0.3	0.2	0.4
Rb content in liver	0.2	0.2	0.5	-0.7	-0.4	-0.0
Se content in liver	0.5	0.6	0.8	0.8	0.9	-0.5
Sr content in liver	1.8	1.5	2.2	1.3	1.5	-0.8
Zn content in liver	21.9	25.5	37.8	-4.9	-3.8	6.1
Bone: minimum diameter	0.6	1.1	1.9	1.0	0.5	-1.4
Time in familiar zone, hab. session 1	0.0	0.0	0.1	0.0	-0.1	-0.3
Time in novel zone, hab. session 1	0.2	0.2	0.3	0.6	0.4	-0.3
Total zone transitions, hab. session 1	0.5	0.7	1.5	0.0	-0.8	-1.2
Total locomotion distance, hab. session 1	0.4	0.6	1.2	-0.8	-1.1	0.1
Locomotion velocity, hab. session 1	0.4	0.6	1.1	-0.9	-1.0	0.3
Time in familiar zone, hab. session 2	1.9	2.2	4.1	1.5	2.0	-0.6
Time in novel zone, hab. session 2	1.3	1.4	1.9	-1.4	-1.4	0.7
Total zone transitions, hab. session 2	0.6	0.8	1.6	-0.8	-1.3	-0.3
Total locomotion distance, hab. session 2	0.3	0.4	0.5	-0.7	-0.7	0.2
Locomotion velocity, hab. session 2	0.4	0.5	0.7	-0.9	-0.8	0.4
Novel to familiar place preference ratio	0.1	0.1	0.2	-0.4	-0.4	0.4
Novelty place preference	0.1	0.1	0.2	-0.3	-0.3	0.4
Time in novel zone, NPP test	0.1	0.1	0.1	-0.2	-0.2	0.4
Total zone transitions, NPP test	0.3	0.5	0.8	-0.6	-0.9	-0.4
Total locomotion distance, NPP test	0.9	1.3	1.9	-1.4	-1.2	0.9
Locomotion velocity, NPP test	0.9	1.2	1.8	-1.4	-1.0	0.9
Intraocular pressure	0.5	0.8	1.3	1.1	0.7	-0.7
Delta distance traveled before/after self-admin	1.6	1.8	2.6	-1.3	-1.6	1.0
Delta ambulatory time before/after self-admin	1.2	2.2	2.7	-1.5	-1.6	1.2
Parametrial fat weight	0.4	1.0	1.2	-0.9	-1.1	0.9
Pavlov. Cond. lever latency	0.4	0.5	0.8	0.8	0.4	-0.9
Pavlov. Cond. magazine entry latency	0.1	0.2	0.4	0.4	0.2	-0.6
Pavlov. Cond. change in total contacts	0.6	0.6	1.1	-1.1	-0.7	0.5
Pavlov. Cond. index score	0.1	0.1	0.2	-0.4	-0.0	0.5
Pavlov. Cond. latency score	0.2	0.3	0.5	-0.6	-0.1	0.7
Pavlov. Cond. lever contacts	0.4	0.5	0.7	-0.8	-0.4	0.9
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	0.0	0.1	0.5
Pavlov. Cond. intertrial magazine entries	0.4	0.5	0.6	-0.7	-0.7	0.6
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.3	-0.4	-0.0	0.6
Pavlov. Cond. response bias	0.1	0.1	0.2	-0.5	-0.5	0.0
Pavlov. Cond. lever latency	0.0	0.1	0.1	0.3	0.3	0.2
Pavlov. Cond. magazine entry latency	0.0	0.1	0.1	0.2	0.4	-0.2
Pavlov. Cond. change in total contacts	0.2	0.5	0.7	-0.9	-0.5	0.6
Pavlov. Cond. index score	0.0	0.0	0.1	0.0	0.3	0.0
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.4	-0.1	0.4
Pavlov. Cond. lever contacts	0.0	0.1	0.2	0.1	0.1	-0.4
Pavlov. Cond. magazine entry number	0.0	0.1	0.2	-0.0	-0.4	0.1
Pavlov. Cond. intertrial magazine entries	0.2	0.4	0.8	0.6	0.9	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.1	-0.1	0.3	0.1
Pavlov. Cond. response bias	0.4	0.6	1.0	0.6	0.6	-1.0
Time in closed arm before self-admin	0.9	1.5	1.7	-1.3	-1.3	1.1
Time in closed arm after self-admin	3.2	3.6	4.5	-2.1	-1.8	1.8
Time in open arm before self-admin	0.5	0.6	1.4	0.7	1.2	-0.2
Time in open arm after self-admin	1.7	1.8	2.2	1.5	1.2	-1.4
Bone: periosteal estimation	0.4	0.9	0.9	0.9	0.9	-1.0
Bone: periosteal perimeter	0.9	1.7	2.0	1.3	1.2	-1.4
Bone: post-yield work	1.5	2.5	3.8	-1.5	-1.9	1.2
Progressive ratio test 1 active lever presses	0.2	0.4	1.1	0.2	-0.2	-1.1
Progressive ratio test 1 breakpoint	0.2	0.3	0.7	-0.0	-0.3	-0.8
Progressive ratio test 1 inactive lever presses	0.3	0.9	1.3	0.7	1.2	-0.9
Progressive ratio test 2 active lever presses	0.6	0.9	1.4	0.8	0.8	-1.2
Progressive ratio test 2 breakpoint	0.6	0.8	1.1	0.8	0.8	-1.0
Progressive ratio test 2 inactive lever presses	0.2	0.8	1.2	0.8	0.7	-1.1
Incentive Sensitization - Responses	0.1	0.2	0.3	0.4	0.5	-0.2
Incentive Sensitization - Breakpoint	0.1	0.3	0.5	0.6	0.7	-0.3
Sum of active levers in priming session hrs 5-6	1.0	1.0	2.3	-0.8	0.1	1.5
Progressive ratio	1.3	3.9	5.1	2.2	2.3	-1.3
Food seeking constrained by brief footshock	0.0	0.0	0.1	-0.3	0.1	0.0
Seeking ratio, punishment vs. effort	1.3	2.8	3.6	-1.9	-1.9	1.2
Retroperitoneal fat weight	0.1	0.3	0.4	0.5	0.7	-0.5
Reaction time number correct	0.0	0.2	0.2	0.5	0.4	-0.3
Reaction time mean minus median	0.2	1.4	2.1	1.2	1.5	-0.8
Reaction time mean minus median AUC	0.1	0.8	1.3	0.9	1.2	-0.5
Reaction time num false alarms	0.7	1.1	2.0	1.2	0.2	-1.4
Reaction time num false alarms AUC	0.9	2.1	3.6	1.6	0.5	-1.9
Reaction time trials correct on left	0.0	0.2	0.2	0.5	0.4	-0.3
Reaction time trials on left	0.1	0.2	0.3	0.6	0.5	-0.3
Reaction time mean	1.3	3.0	4.8	1.7	2.2	-1.1
Reaction time mean AUC	1.5	3.5	5.3	1.9	2.3	-1.3
Median of all reaction times	1.8	2.8	4.4	1.6	2.1	-1.1
Reaction time omissions	1.0	1.6	2.6	1.6	1.3	-0.6
Reaction time false alarm rate	0.6	0.8	1.5	1.0	0.2	-1.2
Reaction time premature initiation rate	0.8	1.2	2.4	1.0	0.5	-1.6
Reaction time premature initiations	0.7	2.2	3.8	1.4	0.9	-1.9
Std. dev. reaction times	0.3	1.1	1.9	1.1	1.4	-0.6
Reaction time trials completed	0.1	0.2	0.3	0.6	0.5	-0.3
Reaction time trials AUC	0.0	0.1	0.2	0.4	0.3	-0.3
Run reversals in cocaine runway, females	0.0	0.0	0.1	-0.0	0.1	0.4
Run reversals in cocaine runway, males	0.2	0.2	0.3	0.4	0.6	-0.3
Latency to leave start box in cocaine runway	1.1	1.5	1.8	-1.3	-1.1	1.2
Latency to leave start box in cocaine runway, F	1.4	1.7	2.3	-1.5	-1.5	0.9
Latency to leave start box in cocaine runway, M	0.5	0.5	1.2	-0.4	0.2	1.1
Std. dev. time between licks in bursts	3.6	6.7	10.8	-2.4	-3.3	1.9
Total sessions with >9 infusions	0.8	1.0	1.7	-1.1	-1.3	0.1
Short access day 1 total inactive lever presses	0.6	1.1	1.5	-1.2	-1.2	0.7
Short access day 10 total inactive lever presses	0.0	0.1	0.1	-0.2	0.0	0.4
Short access day 1 total infusions	0.7	1.5	2.8	-1.2	-1.7	0.3
Short access day 10 total infusions	0.1	0.1	0.3	-0.5	-0.3	-0.1
Short access total infusions	0.3	0.4	0.7	-0.7	-0.8	-0.1
Short access day 1 locomotion	2.1	3.6	5.3	-2.0	-2.3	1.1
Short access day 10 total locomotion	0.2	0.9	1.3	-1.2	-0.5	1.0
Short access total locomotion	1.0	1.6	2.5	-1.6	-0.9	1.1
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.1	0.4	0.2
Compulsive drug intake	0.3	0.4	1.0	0.5	1.0	-0.1
One hour access (shock baseline)	0.0	0.0	0.1	0.1	0.3	-0.2
Social response proportion	0.2	0.2	0.4	0.6	0.3	-0.2
Social responses	0.1	0.1	0.4	-0.1	0.0	0.6
Social time	0.1	0.2	0.5	0.1	0.1	0.7
Soleus weight	1.0	3.0	3.8	1.8	1.4	-2.0
Bone: stiffness	0.1	0.1	0.2	-0.5	-0.1	0.2
Tibialis anterior weight	5.1	17.4	20.2	4.2	3.7	-4.5
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.3	0.2	0.5	-0.1
Time to tail flick, vehicle, after self-admin	0.3	0.6	0.8	0.9	0.7	-0.6
Time to tail flick, test, before self-admin	0.3	0.3	0.7	0.5	0.8	-0.1
Time to tail flick, test, after self-admin	0.2	0.2	0.2	-0.5	-0.4	0.3
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.4	-0.1	-0.7	-0.2
Delta time to tail flick, test, before/after SA	0.4	0.5	1.0	-0.7	-1.0	0.1
Tibia length	1.4	3.8	4.8	1.9	2.2	-1.7
Ambulatory time before self-admin	0.2	0.5	0.5	0.6	0.7	-0.7
Ambulatory time after self-admin	0.5	0.7	1.2	-0.9	-1.1	0.5
Bone: tissue strength	1.3	1.4	1.8	-1.2	-1.3	0.9
Total heroin consumption	0.1	0.1	0.2	-0.1	0.5	0.4
Bone: trabecular number	0.0	0.0	0.1	0.0	0.4	0.1
Bone: trabecular spacing	0.2	0.3	0.8	-0.4	-0.1	0.9
Bone: trabecular thickness	0.5	0.7	0.8	0.8	0.9	-0.9
Bone: trabecular tissue density	0.4	0.7	0.8	0.9	0.7	-0.9
Water consumed over 24 hours	0.0	0.0	0.1	-0.4	0.0	0.1
Number of responses in last shaping day	0.7	0.9	2.4	0.5	0.2	-1.6