Hub : Genes

LOC134485606

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC134485606 0.34 0.16 7.6e-04 0.04 0.04 0.05 0.04 3.2e-02 4.4e-02 2.4e-02 3.9e-02
2 LHb gene expression LOC134485606 0.68 0.15 4.3e-07 0.06 0.1 0.17 0.06 1.3e-02 2.7e-03 6.1e-05 1.5e-02
3 OFC gene expression LOC134485606 0.3 0.15 7.7e-04 0.07 0.01 0.03 0.05 1.1e-02 2.0e-01 5.5e-02 2.8e-02
4 pVTA gene expression LOC134485606 0.38 0.12 0.0e+00 0.32 0.06 0.33 0.26 1.3e-26 1.2e-05 5.6e-27 1.3e-20
5 BLA gene expression LOC134485606 0.24 0.1 4.2e-12 0.18 0.16 0.17 0.17 6.6e-10 9.2e-09 3.6e-09 2.0e-09
6 PL gene expression LOC134485606 0.38 0.12 0.0e+00 0.31 0.3 0.3 0.31 6.1e-34 9.4e-33 7.4e-33 6.5e-34
7 NAcc gene expression LOC134485606 0.32 0.13 0.0e+00 0.27 0.23 0.27 0.11 1.6e-40 3.8e-34 1.4e-40 2.0e-16
8 Brain gene expression LOC134485606 0.29 0.12 8.2e-13 0.07 0.07 0.07 0.07 2.6e-07 5.1e-07 4.2e-07 3.9e-07
9 Adipose gene expression LOC134485606 0.05 0.03 9.8e-05 0.03 0.02 0.01 0.01 7.0e-04 4.0e-03 1.0e-02 6.7e-03
10 IC gene expression LOC134485606 0.21 0.09 7.9e-08 0.08 0.11 0.11 0.1 2.6e-04 2.3e-05 2.7e-05 6.0e-05
11 RMTg gene expression LOC134485606 0.53 0.18 9.8e-09 0.25 0.29 0.24 0.26 2.3e-07 2.2e-08 4.0e-07 1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.93.54.51.91.41.52.01.72.12.12.1-1.9-2.0-1.9
Area under the delay curve0.91.42.1-1.2-0.8-1.4-1.2-0.9-1.2-1.2-1.31.21.41.3
BMI with tail0.72.38.7-1.5-2.4-3.0-0.9-0.9-1.1-0.9-1.11.11.50.5
BMI without tail0.52.89.7-1.9-2.9-3.1-1.1-0.8-1.2-0.9-1.21.11.60.3
Body weight0.41.67.8-1.5-2.8-2.1-0.5-0.4-0.8-0.4-0.60.60.8-0.3
Weight adjusted by age0.00.00.2-0.2-0.40.0-0.1-0.0-0.1-0.1-0.10.1-0.1-0.2
Bone surface3.46.79.22.31.31.92.83.02.82.92.7-2.7-2.7-2.8
Bone volume3.26.38.12.21.42.02.62.82.82.82.6-2.6-2.7-2.7
Breakpoint value in progressive ratio session0.20.41.0-1.0-0.8-0.4-0.50.2-0.6-0.5-0.80.60.40.2
Number of licking bursts0.10.30.60.60.1-0.10.80.70.50.60.5-0.7-0.3-0.4
Context. condit. distance diff. score0.10.10.40.00.6-0.2-0.2-0.3-0.2-0.2-0.10.20.40.4
Locomotion velocity, session 11.21.42.5-1.6-1.2-0.5-1.3-1.1-1.3-1.3-1.41.30.90.7
Locomotion distance, session 10.10.10.5-0.7-0.60.4-0.1-0.0-0.4-0.2-0.40.20.0-0.3
Locomotion velocity, session 21.41.62.8-1.7-1.5-1.1-1.3-1.2-1.4-1.2-1.41.31.20.7
Locomotion distance, session 20.20.31.2-0.9-1.10.4-0.2-0.0-0.3-0.0-0.30.1-0.3-0.8
Locomotion velocity, session 30.20.20.8-0.30.3-0.9-0.5-0.2-0.4-0.4-0.50.10.60.7
Locomotion distance, session 30.50.60.90.80.40.50.80.80.70.90.9-0.9-0.8-0.8
Stereotopy head waving bouts, day 30.10.20.5-0.1-0.00.60.30.70.30.40.0-0.4-0.5-0.4
Stereotopy head waving duration, day 30.40.51.1-1.0-0.3-0.7-0.6-0.3-0.6-0.7-1.00.50.80.7
Locomotion velocity, session 710.311.314.83.11.83.83.23.43.43.63.5-3.4-3.8-3.5
Locomotion distance, session 75.57.19.12.82.23.02.62.62.62.72.8-2.8-2.8-2.3
Stereotopy head waving bouts, day 70.30.30.7-0.8-0.8-0.7-0.4-0.4-0.4-0.5-0.60.50.50.2
Stereotopy head waving duration, day 70.81.01.5-1.2-1.0-1.2-0.9-0.9-0.8-0.9-1.01.01.10.8
Locomotion velocity, session 82.63.14.4-2.1-1.5-1.6-2.0-1.7-1.9-1.8-1.91.81.71.2
Locomotion distance, session 80.10.20.6-0.8-0.3-0.3-0.5-0.5-0.5-0.4-0.50.40.4-0.0
Degree of sensitization distance0.50.52.00.60.71.40.50.70.60.60.5-0.6-0.8-0.6
Degree of sensitization stereotypy1.31.52.5-1.5-1.3-1.6-1.0-1.1-1.1-1.1-1.31.11.30.8
Conditioned locomotion0.00.00.1-0.3-0.3-0.1-0.3-0.3-0.0-0.1-0.10.3-0.1-0.1
Cocaine response after cond. corrected0.30.51.90.81.40.90.60.60.60.50.4-0.8-0.6-0.1
Cocaine response after cond. not corrected0.71.03.11.11.81.20.80.80.90.70.6-1.0-0.9-0.2
Cocaine response before conditioning0.30.40.60.60.60.60.60.60.60.70.7-0.7-0.8-0.6
Saline control response1.11.52.21.00.60.21.31.41.51.51.3-1.3-1.2-1.5
Bone: connectivity density2.43.84.82.11.51.82.11.82.12.12.2-1.8-2.0-1.9
Bone: cortical apparent density0.71.11.7-0.9-0.9-0.9-1.1-1.3-1.1-1.1-0.91.11.00.9
Bone: cortical area0.10.20.8-0.3-0.9-0.80.20.50.20.30.1-0.20.1-0.6
Bone: cortical porosity0.10.10.3-0.00.10.40.30.50.30.30.1-0.3-0.3-0.3
Bone: cortical porosity0.00.00.1-0.3-0.20.30.10.30.10.1-0.1-0.1-0.2-0.2
Bone: cortical thickness0.20.31.1-0.8-1.0-0.8-0.30.1-0.2-0.1-0.40.10.3-0.2
Bone: cortical thickness3.84.67.1-2.7-2.4-2.3-2.1-1.8-2.2-2.1-2.32.02.21.4
Bone: cortical tissue density0.71.11.9-0.9-0.9-0.9-1.1-1.4-1.2-1.2-0.91.21.00.9
Condit. Reinf. active minus inactive responses1.01.27.0-1.6-2.6-0.5-0.8-0.5-0.7-0.3-0.50.8-0.1-0.9
Condit. Reinf. active-inactive response ratio1.41.58.6-1.9-2.9-0.5-0.9-0.6-0.8-0.4-0.70.9-0.1-1.0
Condit. Reinf. active responses0.70.96.6-1.3-2.6-0.2-0.5-0.1-0.40.1-0.20.5-0.3-1.2
Condit. Reinf. inactive responses0.00.00.30.0-0.5-0.20.20.20.00.10.2-0.00.0-0.2
Incentive salience index mean1.01.37.9-1.6-2.8-0.4-0.8-0.4-0.6-0.2-0.50.8-0.2-1.0
Condit. Reinf. lever presses0.50.74.5-1.2-2.1-0.4-0.6-0.5-0.5-0.3-0.40.70.1-0.5
Condit. Reinf. active minus inactive responses3.45.38.01.90.91.72.52.82.42.62.3-2.5-2.5-2.5
Condit. Reinf. active-inactive response ratio1.82.94.11.40.31.01.92.01.82.01.8-1.8-1.8-2.0
Condit. Reinf. active responses5.57.910.52.41.32.62.93.22.83.12.8-3.0-3.1-3.0
Condit. Reinf. inactive responses0.50.81.60.70.51.30.80.90.80.90.8-0.8-1.2-1.0
Condit. Reinf. lever presses1.92.85.11.30.71.41.72.31.71.91.5-1.8-1.8-1.7
Condit. Reinf. lever reinforcers received5.47.510.52.41.42.42.93.22.83.02.7-2.9-3.0-2.9
Conditioned reinforcement - actives2.49.512.13.22.42.53.33.53.33.33.3-3.3-3.0-2.9
Conditioned reinforcement - inactives0.30.71.10.90.70.50.71.10.80.90.8-0.8-1.0-0.8
Conditioned locomotion3.34.96.02.31.71.52.52.32.42.42.4-2.4-2.1-2.0
Patch foraging indifference point 0 sec0.10.21.40.71.20.30.20.20.40.20.3-0.3-0.30.2
Patch foraging indifference point AUC0.20.40.9-0.5-0.90.8-0.8-0.9-0.5-0.5-0.40.80.10.2
Delay disc. indifference point, 0s delay0.10.10.40.5-0.6-0.10.2-0.60.10.10.2-0.10.00.1
Delay disc. indifference point, 16s delay0.81.22.4-1.1-0.5-1.5-1.1-0.6-1.0-1.0-1.21.11.11.1
Delay disc. indifference point, 2s delay0.20.20.7-0.3-0.8-0.20.30.10.30.40.1-0.3-0.3-0.8
Delay disc. indifference point, 24s delay0.20.30.7-0.6-0.3-0.6-0.5-0.3-0.5-0.6-0.70.50.70.8
Delay disc. indifference point, 4s delay2.02.13.8-1.5-0.7-1.9-1.4-1.0-1.4-1.4-1.51.51.81.3
Delay disc. indifference point, 8s delay0.40.71.7-0.6-0.2-0.7-1.0-0.5-0.9-0.9-0.90.91.01.3
Indifference point function ln k0.20.53.1-0.20.4-1.7-0.2-0.0-0.4-0.4-0.40.10.90.7
Indifference point function log k0.20.53.1-0.20.4-1.7-0.2-0.0-0.4-0.4-0.40.10.90.7
Patch foraging total patch changes 0 sec0.00.10.60.30.8-0.1-0.2-0.3-0.1-0.2-0.10.10.10.6
Patch foraging total patch changes 12 sec0.10.21.00.10.51.0-0.3-0.3-0.3-0.3-0.10.30.00.5
Patch foraging total patch changes 18 sec0.51.12.0-1.2-0.8-0.1-1.4-1.2-1.1-1.1-1.11.20.80.9
Patch foraging total patch changes 24 sec0.00.10.4-0.00.60.5-0.3-0.5-0.2-0.3-0.10.30.10.4
Patch foraging total patch changes 6 sec0.20.40.9-0.3-0.30.1-0.8-1.0-0.7-0.7-0.50.90.40.7
Patch foraging time to switch 0 sec0.10.31.4-0.5-0.80.60.40.60.10.40.2-0.2-0.5-1.2
Patch foraging water rate 0 sec0.20.91.8-0.5-0.4-1.0-1.1-1.2-0.8-0.9-0.81.01.01.3
Patch foraging water rate 12 sec0.10.51.31.10.80.30.80.60.70.71.0-0.7-0.6-0.3
Patch foraging water rate 18 sec0.20.40.60.80.10.50.80.50.60.70.8-0.5-0.6-0.6
Patch foraging water rate 24 sec0.40.61.5-0.4-0.4-1.2-0.6-0.9-0.6-0.7-0.60.80.91.0
Patch foraging water rate 6 sec0.71.01.61.31.0-0.11.10.91.11.11.1-1.2-0.6-0.4
Seeking ratio, delayed vs. immediate footshock3.85.49.23.03.02.32.42.02.32.12.4-2.3-1.9-1.2
Distance traveled before self-admin0.40.84.5-0.6-0.6-2.1-0.4-0.2-0.6-0.5-0.50.61.20.6
Distance traveled after self-admin0.10.11.10.2-0.3-1.10.1-0.3-0.0-0.00.10.00.50.1
Extensor digitorum longus weight5.521.936.8-6.1-5.9-5.5-4.6-4.0-4.4-4.1-4.74.44.52.3
Bone: elastic displacement0.50.71.40.4-0.00.80.91.00.70.90.6-0.9-1.0-1.2
Bone: elastic work0.60.81.60.3-0.00.50.91.30.91.00.6-1.1-0.9-1.1
Bone: endosteal estimation1.43.45.61.5-0.00.72.12.12.02.22.1-1.8-1.7-2.4
Bone: endosteal perimeter0.51.31.81.10.40.81.31.21.21.31.3-1.0-1.1-1.3
Epididymis fat weight0.21.12.5-0.9-1.2-1.6-0.9-1.0-1.1-0.9-0.80.71.00.9
Delta time in closed arm before/after self-admin0.40.41.7-0.00.2-1.3-0.3-1.0-0.1-0.4-0.10.10.90.6
Delta time in open arm before/after self-admin0.30.30.90.50.50.50.71.00.40.60.5-0.4-0.6-0.4
Diff in mean of infusions in LGA sessions0.20.31.5-0.9-1.2-0.90.00.3-0.20.0-0.40.20.1-0.5
Delay discount exponential model param0.91.21.71.10.61.31.10.71.11.11.2-1.1-1.3-1.3
Extinction: sum of active levers before priming0.00.00.1-0.3-0.4-0.2-0.20.1-0.1-0.1-0.20.1-0.2-0.1
Active lever presses in extinction session 60.10.10.4-0.20.2-0.2-0.3-0.0-0.3-0.4-0.50.30.60.6
Bone: final force0.20.31.0-0.5-1.0-0.80.10.50.40.40.2-0.4-0.1-0.8
Bone: final moment0.30.51.0-0.0-0.7-0.70.60.90.60.80.5-0.8-0.4-1.0
Food consumed during 24 hour testing period0.91.72.8-1.7-1.6-1.6-1.3-0.8-1.5-1.2-1.41.01.20.9
Glucose1.32.13.2-1.7-1.6-1.8-1.2-1.0-1.6-1.3-1.61.11.41.1
Heart weight0.71.21.7-1.0-1.2-0.9-1.3-1.3-1.0-1.1-1.01.21.01.0
Delay discount hyperbolic model param1.01.31.61.30.81.31.20.81.11.11.3-1.1-1.2-1.1
Intermittent access intake day 1-15 change0.52.54.92.02.21.01.61.51.61.51.6-1.6-1.3-1.1
Intermittent access intake escalation0.52.66.22.12.51.01.61.61.61.51.6-1.6-1.3-0.9
Intermittent access intake escalation 22.54.27.02.62.71.82.11.92.11.92.1-2.1-1.9-1.3
Intermitt. access day 1 inactive lever presses0.44.56.3-1.9-1.9-2.4-2.3-2.5-2.1-2.2-2.12.12.01.9
Intermitt. access day 15 inactive lever presses0.52.74.7-1.2-0.2-0.1-2.1-2.0-1.8-2.0-1.81.81.32.2
Intermitt. access escalation Index0.82.54.2-1.4-0.4-0.9-1.9-2.1-1.7-1.8-1.61.71.51.8
Intermittent access day 1 total infusions1.64.89.32.21.73.12.12.32.02.12.0-2.0-2.3-2.0
Intermittent access day 15 total infusions3.58.511.83.43.42.82.93.22.82.82.8-2.8-2.7-2.1
Intermittent access terminal intake (last 3 days)4.57.910.83.23.23.32.73.02.72.72.7-2.7-2.6-2.0
Intermittent access total infusions5.05.97.82.72.72.82.42.72.32.32.3-2.3-2.3-1.8
Intermittent access day 1 locomotion0.71.32.71.21.21.61.01.21.01.01.0-1.0-1.1-0.9
Intermittent access day 15 total locomotion0.41.41.71.30.41.31.31.01.21.21.2-1.2-1.2-1.2
Intermittent access total locomotion1.61.93.81.61.31.91.31.21.31.31.3-1.3-1.5-1.1
Intermittent access standard deviation0.62.95.42.32.31.41.81.81.71.61.7-1.7-1.2-0.7
Left kidney weight0.10.51.3-0.3-0.0-1.0-0.6-0.6-0.5-0.7-0.70.50.91.2
Right kidney weight0.11.02.3-0.9-0.6-1.5-1.0-1.0-0.9-1.0-1.00.81.21.1
Cocaine induced anxiety0.30.91.3-1.0-0.5-1.1-1.1-0.6-1.1-1.0-1.11.11.00.9
Post-drug Anxiety0.91.01.7-1.3-1.3-1.3-1.0-0.7-1.0-0.9-1.01.00.90.5
Baseline Anxiety0.10.10.5-0.0-0.7-0.10.5-0.10.30.30.3-0.3-0.2-0.6
Tail length0.10.52.1-1.1-1.5-1.0-0.7-0.4-0.6-0.4-0.50.30.40.0
Length with tail0.00.21.4-0.5-1.20.0-0.10.10.10.20.2-0.2-0.3-0.6
Length without tail0.10.71.00.80.20.61.00.80.90.90.9-0.9-1.0-0.8
Times rat made contact with spout0.00.00.30.1-0.1-0.60.20.0-0.00.10.1-0.20.10.2
Lifetime Intake3.03.85.92.42.42.41.82.11.71.71.7-1.7-1.8-1.1
Liver weight, left0.20.32.3-0.6-1.5-0.5-0.2-0.0-0.3-0.0-0.20.20.0-0.5
Liver weight, right1.11.92.8-1.2-0.4-1.6-1.5-1.3-1.4-1.5-1.41.21.51.7
Locomotor activity0.20.32.4-0.20.6-1.60.10.10.2-0.0-0.3-0.10.60.3
Locomotor testing distance0.10.21.0-0.10.6-1.00.20.20.50.20.0-0.30.2-0.1
Locomotor testing rearing0.20.83.41.01.90.60.80.70.90.60.7-0.8-0.4-0.1
Locomotion in novel chamber0.10.20.7-0.8-0.8-0.5-0.3-0.2-0.3-0.2-0.20.30.2-0.4
Locomotion in novel chamber post-restriction0.10.30.6-0.40.1-0.4-0.5-0.5-0.6-0.6-0.70.60.80.8
Fecal boli incidents, locomotor time 10.00.00.1-0.2-0.10.3-0.1-0.2-0.3-0.2-0.20.3-0.00.1
Change in fecal boli incidents, locomotor task1.81.94.21.72.01.01.41.71.21.21.4-1.3-0.9-0.6
Time >=10cm from walls, locomotor time 11.31.61.91.41.11.31.41.31.31.31.3-1.3-1.1-1.2
Bouts of movement, locomotor time 11.51.94.5-0.60.6-1.2-1.4-1.6-1.3-1.6-1.21.31.62.1
Total resting periods, locomotor time 10.80.92.4-0.30.7-0.5-1.0-1.1-0.9-1.2-0.80.91.11.6
Rest time, locomotor task time 10.20.20.7-0.1-0.4-0.1-0.4-0.8-0.5-0.5-0.30.40.50.8
Distance moved, locomotor task time 10.00.10.3-0.40.1-0.5-0.20.1-0.0-0.1-0.20.10.2-0.2
Vertical activity count, locomotor time 10.10.71.80.20.3-0.10.91.20.91.00.7-0.9-0.6-1.3
Time >=10cm from walls, locomotor time 20.51.42.21.20.01.01.41.11.21.31.2-1.2-1.1-1.5
Bouts of movement, locomotor time 20.93.15.6-1.3-0.2-1.6-1.6-1.4-1.9-2.0-1.81.92.12.4
Total resting periods, locomotor time 20.93.46.7-1.4-0.1-1.8-1.7-1.4-1.9-2.1-1.92.02.32.6
Rest time, locomotor task time 20.50.92.0-0.8-0.1-1.1-0.9-0.6-0.9-0.9-0.90.91.21.4
Distance moved, locomotor task time 20.10.10.2-0.3-0.2-0.2-0.4-0.5-0.2-0.3-0.20.20.3-0.0
Vertical activity count, locomotor time 20.20.41.7-0.9-1.3-0.8-0.2-0.6-0.4-0.3-0.50.40.5-0.5
Light reinforcement 10.62.83.9-1.6-1.4-0.8-1.9-2.0-1.9-1.8-1.71.91.51.5
Light reinforcement 21.63.65.6-2.0-2.4-1.8-1.9-1.9-2.0-1.8-1.82.11.81.2
Bone: marrow area1.23.05.31.4-0.20.52.02.01.92.12.0-1.7-1.6-2.3
Bone: maximum diameter0.00.10.60.0-0.4-0.80.10.10.10.10.20.10.3-0.2
Bone: maximum force0.10.30.7-0.4-0.5-0.80.30.80.50.50.1-0.6-0.1-0.7
Bone: maximum moment0.30.61.50.1-0.2-0.70.81.20.80.90.5-1.0-0.4-0.9
Mean time between licks in bursts0.10.30.8-0.3-0.90.80.10.50.00.40.1-0.3-0.9-0.9
Mean num. licks in bursts0.10.20.4-0.5-0.1-0.3-0.6-0.6-0.4-0.5-0.40.50.40.4
Cd content in liver2.22.43.2-1.4-0.9-1.8-1.6-1.5-1.6-1.7-1.61.61.61.6
Co content in liver2.12.44.3-1.2-0.0-1.8-1.5-1.3-1.6-1.7-1.71.41.82.1
Cu content in liver1.31.64.21.62.11.41.20.81.21.01.3-1.1-1.0-0.4
Fe content in liver0.91.11.61.00.70.91.21.31.01.10.9-1.2-1.0-1.0
K content in liver0.40.41.20.80.71.10.50.30.60.50.7-0.3-0.7-0.2
Mg content in liver0.70.81.71.00.81.30.70.51.00.81.0-0.6-1.0-0.7
Mn content in liver0.10.10.50.40.20.70.2-0.20.20.20.40.1-0.4-0.3
Na content in liver0.30.30.70.80.50.30.80.60.60.60.7-0.4-0.3-0.2
Rb content in liver0.10.10.3-0.30.3-0.1-0.5-0.4-0.2-0.4-0.40.30.30.5
Se content in liver0.00.10.20.40.10.40.1-0.3-0.1-0.00.30.1-0.10.1
Sr content in liver0.90.81.00.90.50.91.00.80.80.90.8-1.0-0.9-1.0
Zn content in liver1.01.22.41.51.51.51.00.80.80.91.2-0.9-1.1-0.4
Bone: minimum diameter1.32.46.60.4-1.30.71.51.91.41.81.5-1.4-1.6-2.6
Time in familiar zone, hab. session 10.30.30.90.20.6-0.8-0.1-0.2-0.3-0.5-0.30.20.81.0
Time in novel zone, hab. session 10.10.10.4-0.10.10.6-0.2-0.1-0.00.0-0.1-0.0-0.4-0.1
Total zone transitions, hab. session 10.20.30.9-1.0-0.9-0.0-0.5-0.3-0.6-0.4-0.60.40.2-0.1
Total locomotion distance, hab. session 10.30.41.2-0.1-0.60.80.30.60.40.60.4-0.4-0.8-1.1
Locomotion velocity, hab. session 10.20.31.1-0.4-0.90.60.20.30.20.40.2-0.2-0.6-1.1
Time in familiar zone, hab. session 20.50.62.70.41.6-0.4-0.2-0.4-0.3-0.6-0.40.20.71.4
Time in novel zone, hab. session 20.40.41.5-0.0-1.00.20.40.60.50.70.6-0.4-0.7-1.2
Total zone transitions, hab. session 20.40.60.9-0.8-0.0-0.2-0.7-0.8-0.9-0.9-1.00.70.80.8
Total locomotion distance, hab. session 20.00.00.1-0.2-0.30.20.00.0-0.00.0-0.10.0-0.1-0.3
Locomotion velocity, hab. session 20.00.00.1-0.2-0.20.30.00.00.00.10.0-0.0-0.1-0.3
Novel to familiar place preference ratio0.10.10.30.1-0.1-0.40.50.50.20.40.3-0.4-0.1-0.5
Novelty place preference0.10.10.30.20.1-0.50.40.40.10.30.2-0.30.0-0.3
Time in novel zone, NPP test0.10.10.8-0.10.1-0.90.10.2-0.1-0.0-0.1-0.00.40.1
Total zone transitions, NPP test0.40.61.0-0.9-0.7-0.1-0.9-0.9-1.0-0.9-0.90.90.70.6
Total locomotion distance, NPP test0.00.10.3-0.3-0.50.3-0.10.1-0.10.1-0.0-0.0-0.1-0.4
Locomotion velocity, NPP test0.20.30.80.1-0.20.90.30.40.30.50.4-0.4-0.6-0.8
Intraocular pressure0.50.93.1-1.5-1.8-0.9-0.7-0.2-0.9-0.6-0.90.70.7-0.0
Delta distance traveled before/after self-admin2.22.53.92.01.01.71.61.01.71.61.8-1.7-1.6-1.5
Delta ambulatory time before/after self-admin1.72.94.92.01.52.21.61.21.71.61.8-1.7-1.7-1.5
Parametrial fat weight0.00.10.6-0.0-0.80.30.10.20.00.20.2-0.1-0.3-0.4
Pavlov. Cond. lever latency0.10.10.50.20.7-0.1-0.10.0-0.2-0.3-0.3-0.00.30.6
Pavlov. Cond. magazine entry latency0.10.10.4-0.2-0.6-0.30.10.1-0.10.10.1-0.0-0.0-0.4
Pavlov. Cond. change in total contacts0.50.52.1-1.1-1.4-0.9-0.5-0.5-0.5-0.3-0.50.60.4-0.2
Pavlov. Cond. index score0.20.20.8-0.6-0.9-0.4-0.3-0.5-0.4-0.2-0.20.40.2-0.1
Pavlov. Cond. latency score0.10.20.6-0.6-0.8-0.4-0.4-0.5-0.4-0.2-0.20.50.2-0.1
Pavlov. Cond. lever contacts0.30.31.2-0.0-0.70.40.40.20.50.60.6-0.3-0.7-1.1
Pavlov. Cond. magazine entry number0.40.51.10.91.01.00.60.70.60.50.6-0.7-0.6-0.2
Pavlov. Cond. intertrial magazine entries1.11.33.51.20.61.90.90.81.01.01.3-1.0-1.4-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.7-0.5-0.8-0.5-0.2-0.4-0.3-0.1-0.20.40.2-0.1
Pavlov. Cond. response bias0.10.20.9-0.4-0.9-0.60.1-0.10.00.20.10.1-0.0-0.6
Pavlov. Cond. lever latency1.01.42.3-1.2-1.0-1.5-1.1-1.3-1.2-1.2-1.21.11.20.9
Pavlov. Cond. magazine entry latency0.00.00.1-0.3-0.3-0.0-0.10.20.00.0-0.20.10.0-0.0
Pavlov. Cond. change in total contacts0.71.73.10.7-0.31.41.31.61.21.51.2-1.2-1.5-1.7
Pavlov. Cond. index score0.50.71.50.4-0.10.80.81.20.91.00.7-0.8-0.9-1.0
Pavlov. Cond. latency score0.50.81.50.50.10.90.81.20.91.00.7-0.9-1.0-0.9
Pavlov. Cond. lever contacts0.81.22.11.00.51.51.01.21.01.11.1-0.9-1.2-1.0
Pavlov. Cond. magazine entry number0.00.10.30.20.6-0.0-0.1-0.3-0.2-0.2-0.00.00.10.3
Pavlov. Cond. intertrial magazine entries0.00.10.3-0.0-0.50.00.30.3-0.10.20.2-0.2-0.3-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.71.40.4-0.10.90.81.20.81.00.7-0.8-0.9-0.9
Pavlov. Cond. response bias0.71.01.50.70.11.21.01.21.01.11.0-0.9-1.1-1.2
Time in closed arm before self-admin0.10.20.60.70.70.80.10.00.30.20.2-0.3-0.40.1
Time in closed arm after self-admin0.70.82.3-0.00.5-1.5-0.7-1.3-0.5-0.8-0.60.51.11.1
Time in open arm before self-admin0.30.40.70.40.30.10.80.80.70.80.8-0.7-0.4-0.8
Time in open arm after self-admin0.20.20.7-0.6-0.2-0.80.10.9-0.20.1-0.20.20.2-0.0
Bone: periosteal estimation0.81.94.40.6-0.9-0.11.51.71.41.71.5-1.3-1.2-2.1
Bone: periosteal perimeter0.20.40.70.5-0.2-0.30.70.90.70.80.7-0.7-0.4-0.8
Bone: post-yield work1.22.04.91.72.20.41.61.71.51.31.1-1.6-0.8-0.3
Progressive ratio test 1 active lever presses0.61.03.31.31.01.80.80.90.80.80.8-0.8-1.0-0.4
Progressive ratio test 1 breakpoint0.71.13.61.40.91.90.80.90.90.90.9-0.9-1.0-0.5
Progressive ratio test 1 inactive lever presses0.00.10.30.4-0.00.50.20.40.20.30.2-0.2-0.4-0.3
Progressive ratio test 2 active lever presses4.66.58.32.82.02.32.62.92.62.72.6-2.6-2.5-2.2
Progressive ratio test 2 breakpoint4.96.28.12.72.02.32.62.82.62.62.6-2.6-2.4-2.1
Progressive ratio test 2 inactive lever presses0.31.11.81.21.40.71.11.31.01.01.0-1.0-0.8-0.7
Incentive Sensitization - Responses2.36.37.82.41.32.02.62.72.72.82.7-2.7-2.6-2.7
Incentive Sensitization - Breakpoint2.76.17.52.41.41.92.62.72.62.72.6-2.6-2.6-2.6
Sum of active levers in priming session hrs 5-61.51.41.81.0-0.31.31.21.31.21.31.1-1.2-1.3-1.2
Progressive ratio0.30.92.40.11.1-1.6-0.5-0.7-0.4-0.7-0.50.41.31.5
Food seeking constrained by brief footshock0.50.63.1-1.1-1.8-0.8-0.4-0.2-0.5-0.2-0.40.50.2-0.6
Seeking ratio, punishment vs. effort0.30.73.6-0.7-1.90.70.10.3-0.00.40.10.0-0.9-1.4
Retroperitoneal fat weight0.10.31.5-0.5-1.2-0.3-0.3-0.4-0.6-0.4-0.20.40.20.1
Reaction time number correct0.51.82.70.81.10.71.31.61.61.61.2-1.5-1.4-1.5
Reaction time mean minus median1.17.110.2-2.8-1.9-1.3-2.9-2.4-3.2-3.1-3.22.82.52.6
Reaction time mean minus median AUC1.06.59.2-2.9-2.1-1.3-2.7-2.3-3.0-2.9-3.02.72.42.3
Reaction time num false alarms2.33.84.91.80.91.52.22.22.12.22.1-2.0-2.1-2.1
Reaction time num false alarms AUC1.73.94.71.91.11.72.12.02.12.22.1-1.9-2.1-2.0
Reaction time trials correct on left0.51.82.70.81.10.71.31.61.61.61.2-1.5-1.4-1.5
Reaction time trials on left0.51.62.40.71.00.81.21.51.61.51.1-1.4-1.4-1.5
Reaction time mean0.92.03.1-1.5-1.6-0.6-1.5-1.3-1.8-1.6-1.51.61.30.9
Reaction time mean AUC0.82.03.1-1.6-1.6-0.6-1.5-1.2-1.8-1.6-1.61.61.30.8
Median of all reaction times0.30.51.6-0.9-1.3-0.3-0.7-0.6-0.9-0.7-0.60.80.60.0
Reaction time omissions3.65.88.8-3.0-2.4-0.5-2.8-2.3-2.8-2.6-2.92.71.71.7
Reaction time false alarm rate0.30.40.80.90.30.60.80.60.60.60.8-0.5-0.6-0.5
Reaction time premature initiation rate0.30.41.81.01.30.50.40.20.60.30.5-0.4-0.20.3
Reaction time premature initiations0.31.02.81.21.70.70.90.81.21.00.9-1.0-0.8-0.4
Std. dev. reaction times1.44.67.1-2.2-1.5-0.9-2.3-1.9-2.7-2.5-2.62.32.12.1
Reaction time trials completed0.51.62.40.71.00.81.21.51.61.51.1-1.4-1.4-1.5
Reaction time trials AUC0.51.62.30.60.90.81.21.51.51.51.1-1.4-1.4-1.5
Run reversals in cocaine runway, females0.30.30.7-0.6-0.9-0.8-0.3-0.4-0.4-0.4-0.40.40.70.2
Run reversals in cocaine runway, males0.80.82.1-1.4-1.4-0.7-0.9-0.6-0.8-0.7-1.10.80.70.1
Latency to leave start box in cocaine runway0.40.51.30.90.41.10.70.60.60.60.8-0.6-0.6-0.4
Latency to leave start box in cocaine runway, F1.82.33.51.91.81.61.51.41.51.31.5-1.5-1.3-0.9
Latency to leave start box in cocaine runway, M1.81.74.1-1.6-2.0-0.5-1.4-1.3-1.4-1.2-1.21.41.00.7
Std. dev. time between licks in bursts0.30.51.00.50.00.60.60.70.70.80.8-0.6-0.9-1.0
Total sessions with >9 infusions0.70.93.01.31.71.30.50.90.60.60.6-0.6-0.8-0.1
Short access day 1 total inactive lever presses0.10.30.90.51.00.5-0.3-0.3-0.2-0.4-0.20.20.11.0
Short access day 10 total inactive lever presses0.21.11.9-0.7-0.6-1.3-1.0-1.4-1.0-1.1-1.01.01.11.2
Short access day 1 total infusions0.30.62.11.31.41.10.50.60.50.40.5-0.5-0.50.2
Short access day 10 total infusions1.62.65.21.82.22.31.51.91.31.31.3-1.3-1.4-0.8
Short access total infusions0.91.23.21.41.61.80.81.10.80.80.8-0.8-1.1-0.4
Short access day 1 locomotion0.10.10.30.20.4-0.5-0.2-0.0-0.2-0.2-0.20.20.40.6
Short access day 10 total locomotion0.10.50.7-0.70.2-0.4-0.8-0.3-0.8-0.8-0.80.80.60.7
Short access total locomotion0.10.20.60.60.70.10.30.50.30.30.3-0.3-0.2-0.0
One hour access (0.3 mA shock)6.47.610.53.22.52.53.02.62.92.82.9-2.9-2.6-2.3
Compulsive drug intake0.50.71.9-0.6-1.4-1.3-0.7-1.0-0.6-0.6-0.60.60.90.4
One hour access (shock baseline)4.211.013.43.73.43.43.63.33.33.33.3-3.3-3.1-2.6
Social response proportion0.91.11.7-1.2-0.2-1.0-1.1-0.7-1.1-1.1-1.31.01.01.2
Social responses1.82.33.2-1.6-0.4-1.7-1.6-1.3-1.4-1.5-1.71.51.61.8
Social time0.10.10.9-0.20.40.9-0.40.1-0.0-0.1-0.2-0.0-0.50.1
Soleus weight0.61.72.7-1.6-1.6-1.6-1.4-1.1-1.2-1.1-1.21.11.30.7
Bone: stiffness0.10.10.5-0.7-0.3-0.7-0.40.1-0.1-0.2-0.50.10.30.1
Tibialis anterior weight2.910.126.9-4.3-5.2-4.0-2.8-2.6-2.6-2.3-2.72.92.80.4
Time to tail flick, vehicle, before self-admin0.91.11.51.00.21.01.20.61.21.21.1-1.2-1.1-1.1
Time to tail flick, vehicle, after self-admin1.53.03.92.01.91.41.81.91.81.81.7-1.8-1.5-1.3
Time to tail flick, test, before self-admin0.20.30.5-0.20.1-0.5-0.4-0.6-0.5-0.6-0.50.50.70.7
Time to tail flick, test, after self-admin0.50.51.20.91.11.00.50.70.60.50.7-0.6-0.6-0.0
Delta time to tail flick, vehicle, before/after SA1.71.82.91.51.71.51.21.61.31.21.2-1.3-1.2-0.8
Delta time to tail flick, test, before/after SA0.10.10.2-0.30.2-0.2-0.30.3-0.3-0.2-0.20.30.20.4
Tibia length0.41.02.01.41.4-0.21.21.10.80.91.0-1.2-0.6-0.1
Ambulatory time before self-admin0.41.15.2-1.0-0.9-2.3-0.7-0.4-0.9-0.7-0.70.91.30.7
Ambulatory time after self-admin0.30.40.80.70.00.10.80.50.70.80.9-0.7-0.4-0.8
Bone: tissue strength1.01.02.21.41.50.71.10.91.00.91.0-1.1-0.8-0.2
Total heroin consumption0.81.02.70.60.60.81.11.60.91.00.8-0.9-1.0-1.1
Bone: trabecular number0.61.11.61.20.90.61.20.81.21.11.3-1.0-1.0-0.9
Bone: trabecular spacing1.21.82.6-1.4-1.5-0.2-1.6-1.4-1.6-1.4-1.31.61.00.9
Bone: trabecular thickness2.23.13.81.81.21.21.92.01.91.91.9-2.0-1.7-1.6
Bone: trabecular tissue density3.46.08.5-2.7-1.7-1.3-2.8-2.3-2.8-2.7-2.92.52.22.4
Water consumed over 24 hours0.10.31.3-0.4-0.8-1.1-0.3-0.4-0.3-0.2-0.20.30.40.2
Number of responses in last shaping day0.10.10.30.60.5-0.30.30.30.30.20.3-0.3-0.20.0