LOC134485553

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC134485553 0.84 0.11 2.1e-06 0.04 0.06 0.06 0.03 8.1e-05 3.1e-07 2.3e-07 1.6e-04
2 IC gene expression LOC134485553 0.91 0.06 0.0e+00 0.33 0.38 0.38 0.35 2.0e-14 6.3e-17 3.4e-17 2.8e-15
3 OFC intron excision ratio chr2_1127100_1133017 0.2 0.18 5.9e-03 0.09 0.07 0.08 0.07 4.8e-03 9.4e-03 7.2e-03 7.9e-03
4 Brain gene expression LOC134485553 0.86 0.1 0.0e+00 0.21 0.2 0.2 0.2 5.0e-19 4.4e-18 1.0e-18 1.3e-18
5 PL intron excision ratio chr2_1133045_1133365 0.07 0.06 4.4e-07 0.06 0.06 0.06 0.06 3.4e-07 5.0e-07 4.8e-07 4.1e-07
6 Brain intron excision ratio chr2_1133452_1163297 0.04 0.04 2.9e-04 0.03 0.03 0.04 0.03 3.8e-04 4.1e-04 2.8e-04 4.0e-04
7 Brain intron excision ratio chr2_1133045_1133365 0.07 0.07 6.8e-06 0.05 0.05 0.05 0.05 1.4e-05 1.6e-05 1.1e-05 1.4e-05
8 OFC gene expression LOC134485553 0.62 0.24 1.8e-10 0.38 0.36 0.38 0.38 7.0e-10 1.5e-09 4.6e-10 6.1e-10
9 IC isoform ratio XR_010063670.1 0.07 0.07 9.3e-03 0.02 0.02 0.01 0.01 4.1e-02 6.2e-02 1.0e-01 8.5e-02
10 IC isoform ratio XR_010063671.1 0.07 0.07 7.9e-03 0.02 0.02 0.02 0.01 4.1e-02 6.5e-02 6.3e-02 8.8e-02
11 pVTA mRNA stability LOC134485553 0.04 0.04 3.1e-03 0.03 0.03 0.03 0.03 3.3e-03 2.9e-03 3.8e-03 4.0e-03
12 Adipose gene expression LOC134485553 0.19 0.15 0.0e+00 0.13 0.12 0.13 0.13 7.8e-14 9.3e-14 7.8e-14 7.6e-14
13 Brain mRNA stability LOC134485553 0.18 0.13 1.7e-16 0.17 0.17 0.17 0.17 9.8e-16 5.6e-16 4.9e-16 6.9e-16
14 pVTA isoform ratio XR_010063670.1 0.09 0.12 1.1e-04 0.05 0.05 0.04 0.05 8.3e-05 8.6e-05 2.2e-04 7.6e-05
15 IC intron excision ratio chr2_1133045_1133365 0.09 0.08 3.1e-03 0.04 0.04 0.04 0.04 5.9e-03 8.2e-03 7.9e-03 9.1e-03
16 pVTA isoform ratio XR_010063671.1 0.09 0.12 8.7e-05 0.05 0.05 0.04 0.05 6.5e-05 7.2e-05 2.0e-04 6.9e-05
17 Brain isoform ratio XR_010063670.1 0.03 0.03 4.7e-03 0.02 0.02 0.02 0.02 3.2e-03 3.0e-03 3.2e-03 2.7e-03
18 Brain isoform ratio XR_010063671.1 0.03 0.03 5.5e-03 0.02 0.02 0.02 0.02 3.8e-03 3.5e-03 3.6e-03 3.2e-03
19 NAcc gene expression LOC134485553 0.02 0.02 4.5e-03 0.01 0.01 0 0.01 4.8e-03 9.8e-03 6.6e-02 8.5e-03
20 OFC isoform ratio XR_010063671.1 0.18 0.17 9.3e-03 0.06 0.05 0.05 0.05 1.4e-02 2.4e-02 2.2e-02 2.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density7.213.415.01.93.33.73.73.83.73.73.83.8-3.83.8-3.7-3.8-3.63.6-3.6-3.73.7-3.9-3.9
Area under the delay curve0.10.10.2-0.3-0.3-0.4-0.4-0.4-0.3-0.4-0.4-0.30.3-0.40.30.40.4-0.40.40.4-0.40.40.3
BMI with tail1.75.810.43.23.02.42.52.22.32.42.22.2-2.22.2-2.4-2.2-2.42.4-2.4-2.42.4-2.1-2.0
BMI without tail1.26.521.64.63.72.52.62.02.32.52.12.0-2.02.1-2.4-2.0-2.52.5-2.5-2.52.5-1.8-1.8
Body weight1.67.121.44.63.82.62.72.12.42.62.32.2-2.22.2-2.6-2.2-2.72.7-2.7-2.62.6-1.9-1.9
Weight adjusted by age1.13.35.42.31.91.91.81.81.81.81.71.8-1.81.7-1.8-1.7-1.81.8-1.8-1.81.8-1.7-1.7
Bone surface1.02.02.31.01.31.51.51.51.51.41.51.5-1.51.5-1.4-1.5-1.41.4-1.4-1.41.4-1.5-1.5
Bone volume3.57.07.61.72.52.72.72.82.72.72.82.8-2.82.8-2.7-2.7-2.62.6-2.6-2.72.7-2.8-2.8
Breakpoint value in progressive ratio session0.10.10.3-0.0-0.5-0.4-0.5-0.3-0.4-0.4-0.4-0.20.2-0.40.40.40.4-0.40.40.4-0.40.40.2
Number of licking bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Context. condit. distance diff. score0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving bouts, day 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving duration, day 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving bouts, day 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving duration, day 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 80.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 80.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Degree of sensitization distance0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Degree of sensitization stereotypy0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Conditioned locomotion2.12.53.00.41.31.71.71.71.61.61.71.7-1.71.7-1.6-1.7-1.51.5-1.5-1.51.5-1.7-1.7
Cocaine response after cond. corrected2.43.64.2-1.2-1.6-2.0-1.9-2.0-2.0-1.9-2.0-2.02.0-2.01.92.01.8-1.81.81.8-1.82.02.0
Cocaine response after cond. not corrected1.31.92.4-0.5-1.0-1.4-1.4-1.5-1.5-1.4-1.5-1.51.5-1.51.31.51.2-1.21.21.2-1.21.61.6
Cocaine response before conditioning0.40.51.21.10.80.70.70.70.70.70.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.70.7-0.6-0.6
Saline control response1.01.41.70.70.91.21.21.31.21.21.31.3-1.31.3-1.2-1.3-1.21.2-1.2-1.21.2-1.3-1.3
Bone: connectivity density3.65.77.50.01.72.42.32.62.52.42.62.6-2.62.6-2.4-2.6-2.32.3-2.3-2.32.3-2.7-2.7
Bone: cortical apparent density0.10.10.20.00.30.40.40.40.40.30.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.40.4-0.4-0.4
Bone: cortical area2.74.45.11.32.02.32.22.22.22.22.22.2-2.22.2-2.1-2.2-2.02.0-2.0-2.02.0-2.2-2.2
Bone: cortical porosity1.11.21.60.90.91.31.21.21.11.11.21.2-1.21.2-1.1-1.1-0.90.9-0.9-1.01.0-1.2-1.2
Bone: cortical porosity2.42.73.41.31.41.81.71.71.71.61.81.7-1.71.7-1.6-1.7-1.51.5-1.5-1.51.5-1.7-1.7
Bone: cortical thickness5.59.210.51.22.73.23.13.23.13.13.23.2-3.23.2-3.0-3.2-3.03.0-3.0-3.03.0-3.2-3.2
Bone: cortical thickness0.30.30.50.40.70.60.60.50.60.60.50.5-0.50.5-0.6-0.6-0.60.6-0.6-0.60.6-0.6-0.6
Bone: cortical tissue density0.00.00.0-0.10.00.10.00.10.00.00.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.1-0.1
Condit. Reinf. active minus inactive responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. active-inactive response ratio0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. active responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. inactive responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Incentive salience index mean0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. active minus inactive responses0.60.91.10.50.80.90.91.01.01.01.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.0-1.0-1.0
Condit. Reinf. active-inactive response ratio0.91.41.50.81.21.11.11.21.21.21.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.2-1.2-1.2
Condit. Reinf. active responses0.20.30.4-0.20.10.40.40.60.50.50.60.6-0.60.6-0.5-0.6-0.50.5-0.5-0.50.5-0.7-0.7
Condit. Reinf. inactive responses0.60.91.8-1.3-1.3-1.0-1.0-0.8-0.9-1.0-0.9-0.80.8-0.80.90.81.0-1.01.01.0-1.00.80.8
Condit. Reinf. lever presses0.20.30.4-0.1-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.50.5-0.50.50.50.6-0.60.60.5-0.50.50.5
Condit. Reinf. lever reinforcers received0.10.10.2-0.3-0.10.10.10.30.30.20.30.3-0.30.3-0.3-0.4-0.20.2-0.2-0.20.2-0.4-0.4
Conditioned reinforcement - actives0.00.10.2-0.3-0.2-0.2-0.4-0.3-0.2-0.2-0.2-0.20.2-0.20.20.20.2-0.20.20.2-0.20.20.4
Conditioned reinforcement - inactives0.00.00.20.40.2-0.0-0.1-0.1-0.1-0.0-0.1-0.10.1-0.10.10.10.1-0.10.10.1-0.10.20.1
Conditioned locomotion0.00.00.2-0.4-0.3-0.1-0.2-0.0-0.0-0.1-0.00.0-0.0-0.00.0-0.00.0-0.00.00.0-0.0-0.10.0
Patch foraging indifference point 0 sec1.85.05.72.42.32.32.32.32.32.32.22.3-2.32.2-2.2-2.2-2.22.2-2.2-2.22.2-2.2-2.1
Patch foraging indifference point AUC0.20.52.1-1.5-1.1-0.7-0.6-0.3-0.5-0.7-0.5-0.40.4-0.50.70.50.8-0.80.80.7-0.70.40.4
Delay disc. indifference point, 0s delay0.40.50.70.5-0.3-0.6-0.6-0.7-0.7-0.6-0.7-0.80.8-0.70.60.80.6-0.60.60.7-0.70.80.8
Delay disc. indifference point, 16s delay0.00.10.7-0.8-0.3-0.2-0.2-0.1-0.1-0.2-0.1-0.00.0-0.10.10.10.2-0.20.20.2-0.20.1-0.1
Delay disc. indifference point, 2s delay0.20.20.9-1.0-0.6-0.4-0.4-0.3-0.4-0.4-0.4-0.40.4-0.40.40.40.4-0.40.40.4-0.40.30.3
Delay disc. indifference point, 24s delay0.10.11.51.20.50.00.0-0.1-0.00.0-0.10.0-0.0-0.1-0.00.2-0.00.0-0.0-0.00.00.30.1
Delay disc. indifference point, 4s delay0.90.91.3-0.4-0.8-1.0-1.0-1.1-1.0-1.0-1.0-1.01.0-1.01.01.01.0-1.01.01.0-1.01.11.0
Delay disc. indifference point, 8s delay0.00.00.30.50.2-0.0-0.0-0.2-0.1-0.0-0.1-0.10.1-0.10.00.10.0-0.00.00.0-0.00.20.1
Indifference point function ln k2.05.99.12.63.02.62.52.12.42.52.32.2-2.22.3-2.5-2.3-2.62.6-2.6-2.52.5-2.0-2.2
Indifference point function log k2.05.99.12.63.02.62.52.12.42.52.32.2-2.22.3-2.5-2.3-2.62.6-2.6-2.52.5-2.0-2.2
Patch foraging total patch changes 0 sec1.64.85.92.42.32.32.32.22.22.22.22.2-2.22.1-2.1-2.1-2.12.1-2.1-2.12.1-2.1-2.1
Patch foraging total patch changes 12 sec0.10.20.3-0.3-0.10.40.50.60.40.30.50.6-0.60.5-0.2-0.4-0.10.1-0.1-0.20.2-0.6-0.6
Patch foraging total patch changes 18 sec0.10.20.6-0.4-0.30.30.40.70.50.40.50.7-0.70.5-0.4-0.5-0.30.3-0.3-0.30.3-0.8-0.7
Patch foraging total patch changes 24 sec0.62.03.10.41.01.31.41.81.51.41.41.7-1.71.4-1.3-1.5-1.31.3-1.3-1.31.3-1.6-1.5
Patch foraging total patch changes 6 sec0.20.30.90.90.30.70.70.70.60.50.60.7-0.70.6-0.4-0.5-0.40.4-0.4-0.40.4-0.8-0.6
Patch foraging time to switch 0 sec0.41.41.7-0.4-1.2-1.2-1.3-1.3-1.3-1.2-1.2-1.31.3-1.21.11.31.1-1.11.11.2-1.21.21.2
Patch foraging water rate 0 sec3.312.317.94.24.03.53.63.43.53.53.43.4-3.43.4-3.5-3.3-3.53.5-3.5-3.53.5-3.2-3.1
Patch foraging water rate 12 sec0.93.74.02.01.92.02.02.01.91.91.91.9-1.91.9-1.9-1.9-1.91.9-1.9-1.91.9-2.0-1.8
Patch foraging water rate 18 sec2.65.96.91.42.52.62.62.52.52.52.42.4-2.42.4-2.4-2.5-2.52.5-2.5-2.52.5-2.5-2.5
Patch foraging water rate 24 sec3.95.66.82.02.62.52.52.42.42.42.32.4-2.42.3-2.4-2.3-2.42.4-2.4-2.42.4-2.3-2.4
Patch foraging water rate 6 sec2.63.84.12.01.91.92.01.81.92.01.91.8-1.81.9-1.9-1.9-2.02.0-2.0-2.02.0-1.9-1.9
Seeking ratio, delayed vs. immediate footshock0.20.30.50.3-0.2-0.5-0.5-0.7-0.6-0.5-0.7-0.70.7-0.70.60.60.5-0.50.50.5-0.50.70.6
Distance traveled before self-admin0.51.11.4-0.40.81.21.11.11.11.11.10.9-0.91.1-1.0-1.1-1.01.0-1.0-1.01.0-1.1-1.2
Distance traveled after self-admin0.30.50.8-0.30.40.80.70.70.80.70.80.8-0.80.8-0.7-0.8-0.60.6-0.6-0.70.7-0.9-0.7
Extensor digitorum longus weight0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Bone: elastic displacement0.40.50.9-1.0-0.8-0.6-0.7-0.7-0.7-0.7-0.6-0.70.7-0.70.70.70.7-0.70.70.7-0.70.60.6
Bone: elastic work1.11.51.70.41.11.31.31.31.21.21.31.3-1.31.3-1.2-1.3-1.21.2-1.2-1.21.2-1.3-1.3
Bone: endosteal estimation0.20.52.21.5-0.0-0.5-0.5-0.7-0.7-0.5-0.7-0.70.7-0.70.60.80.6-0.60.60.6-0.60.90.9
Bone: endosteal perimeter0.40.91.10.1-0.6-0.8-0.8-1.0-1.0-0.9-1.0-1.01.0-1.01.01.01.0-1.01.01.0-1.01.11.1
Epididymis fat weight1.15.46.20.52.22.52.42.52.42.32.42.4-2.42.4-2.3-2.4-2.32.3-2.3-2.32.3-2.4-2.5
Delta time in closed arm before/after self-admin1.11.01.50.50.61.01.01.11.11.01.11.1-1.11.1-1.0-1.1-1.01.0-1.0-1.01.0-1.2-1.0
Delta time in open arm before/after self-admin2.93.510.43.22.61.91.81.51.71.81.61.8-1.81.6-1.8-1.5-1.71.7-1.7-1.71.7-1.3-1.6
Diff in mean of infusions in LGA sessions0.30.51.0-0.40.30.60.61.00.80.70.80.8-0.80.8-0.7-0.8-0.60.6-0.6-0.70.7-0.9-0.9
Delay discount exponential model param0.10.10.10.30.20.30.30.40.30.30.30.2-0.20.3-0.3-0.3-0.30.3-0.3-0.30.3-0.3-0.3
Extinction: sum of active levers before priming0.10.22.91.70.40.10.0-0.1-0.00.0-0.1-0.00.0-0.0-0.00.1-0.00.0-0.0-0.00.00.10.1
Active lever presses in extinction session 60.00.00.1-0.1-0.00.10.20.30.20.10.20.3-0.30.2-0.2-0.2-0.10.1-0.1-0.20.2-0.3-0.2
Bone: final force1.72.75.42.31.81.81.81.61.61.71.71.6-1.61.6-1.6-1.5-1.51.5-1.5-1.51.5-1.5-1.5
Bone: final moment1.72.74.92.21.81.81.81.61.61.71.71.6-1.61.7-1.6-1.5-1.51.5-1.5-1.51.5-1.5-1.5
Food consumed during 24 hour testing period0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Glucose0.10.21.20.91.10.40.50.10.30.50.20.0-0.00.2-0.4-0.3-0.50.5-0.5-0.50.5-0.0-0.1
Heart weight1.01.63.61.71.91.31.31.01.21.31.21.1-1.11.2-1.3-1.1-1.31.3-1.3-1.31.3-1.0-1.0
Delay discount hyperbolic model param0.20.20.30.40.40.50.50.50.40.50.50.4-0.40.4-0.4-0.5-0.50.5-0.5-0.50.5-0.5-0.4
Intermittent access intake day 1-15 change0.10.46.4-2.5-0.8-0.2-0.3-0.2-0.2-0.2-0.1-0.20.2-0.10.30.00.3-0.30.30.3-0.3-0.1-0.0
Intermittent access intake escalation0.00.34.3-2.1-0.30.20.10.20.20.10.30.2-0.20.3-0.1-0.3-0.10.1-0.1-0.10.1-0.4-0.4
Intermittent access intake escalation 20.20.35.5-2.3-0.7-0.2-0.3-0.1-0.2-0.2-0.1-0.10.1-0.10.20.10.3-0.30.30.3-0.3-0.00.1
Intermitt. access day 1 inactive lever presses0.11.61.8-0.9-1.1-1.3-1.2-1.3-1.3-1.3-1.3-1.31.3-1.31.21.31.2-1.21.21.3-1.31.31.2
Intermitt. access day 15 inactive lever presses0.31.41.90.1-0.8-1.2-1.1-1.3-1.2-1.2-1.3-1.21.2-1.31.21.31.2-1.21.21.2-1.21.41.3
Intermitt. access escalation Index0.10.30.5-0.30.20.50.40.70.50.50.60.6-0.60.6-0.4-0.6-0.40.4-0.4-0.40.4-0.6-0.7
Intermittent access day 1 total infusions0.82.42.61.01.41.61.51.61.61.61.61.6-1.61.6-1.6-1.6-1.61.6-1.6-1.61.6-1.6-1.5
Intermittent access day 15 total infusions0.82.02.9-1.10.71.41.31.51.51.41.51.5-1.51.5-1.4-1.6-1.31.3-1.3-1.31.3-1.7-1.5
Intermittent access terminal intake (last 3 days)0.71.32.2-1.40.31.11.01.21.21.11.21.2-1.21.3-1.1-1.3-1.01.0-1.0-1.01.0-1.5-1.3
Intermittent access total infusions2.12.53.6-0.80.91.61.51.71.71.61.71.7-1.71.7-1.6-1.8-1.51.5-1.5-1.51.5-1.9-1.7
Intermittent access day 1 locomotion0.50.91.10.50.80.90.81.01.01.01.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.0-1.1-0.9
Intermittent access day 15 total locomotion0.62.43.6-0.70.81.51.51.71.61.51.61.6-1.61.6-1.5-1.7-1.51.5-1.5-1.51.5-1.9-1.7
Intermittent access total locomotion1.41.72.5-0.20.81.31.21.41.41.31.41.4-1.41.4-1.3-1.5-1.31.3-1.3-1.31.3-1.6-1.3
Intermittent access standard deviation0.10.71.0-1.00.60.90.90.90.90.80.90.9-0.90.9-0.8-1.0-0.80.8-0.8-0.80.8-1.0-0.9
Left kidney weight2.016.029.25.45.13.94.03.63.94.03.73.6-3.63.7-4.0-3.7-4.14.1-4.1-4.14.1-3.4-3.3
Right kidney weight1.610.926.75.24.33.23.22.93.13.33.02.9-2.93.0-3.3-2.9-3.43.4-3.4-3.33.3-2.7-2.6
Cocaine induced anxiety0.10.41.1-1.1-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.50.5-0.60.60.60.6-0.60.60.6-0.60.50.6
Post-drug Anxiety0.30.32.0-1.4-0.7-0.5-0.5-0.5-0.5-0.5-0.4-0.40.4-0.40.50.40.5-0.50.50.5-0.50.40.4
Baseline Anxiety0.10.20.4-0.20.20.40.40.40.40.40.40.4-0.40.4-0.4-0.5-0.40.4-0.4-0.40.4-0.5-0.6
Tail length0.52.612.13.52.71.51.51.11.41.51.21.1-1.11.2-1.5-1.2-1.61.6-1.6-1.61.6-0.8-0.9
Length with tail0.52.29.93.22.41.41.40.91.31.41.11.0-1.01.1-1.4-1.1-1.51.5-1.5-1.41.4-0.8-0.8
Length without tail0.00.20.30.60.50.50.50.40.50.50.50.4-0.40.5-0.5-0.5-0.50.5-0.5-0.50.5-0.5-0.4
Times rat made contact with spout0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Lifetime Intake2.83.44.7-0.51.21.81.82.01.91.82.02.0-2.02.0-1.9-2.1-1.81.8-1.8-1.81.8-2.2-2.1
Liver weight, left0.00.00.2-0.0-0.4-0.0-0.00.00.0-0.00.00.0-0.00.00.1-0.00.2-0.20.20.1-0.1-0.3-0.3
Liver weight, right1.11.92.7-1.5-1.7-1.3-1.3-1.3-1.3-1.4-1.3-1.41.4-1.31.41.31.5-1.51.51.4-1.41.31.0
Locomotor activity0.30.50.9-0.20.20.70.70.80.70.70.80.8-0.80.8-0.7-0.8-0.70.7-0.7-0.70.7-0.9-0.9
Locomotor testing distance0.61.65.0-2.2-1.8-1.1-1.2-1.0-1.2-1.2-1.1-1.11.1-1.11.31.01.2-1.21.21.2-1.21.01.0
Locomotor testing rearing0.10.54.9-2.2-1.2-0.5-0.6-0.3-0.5-0.6-0.4-0.40.4-0.40.60.30.6-0.60.60.6-0.60.30.2
Locomotion in novel chamber0.10.11.11.00.4-0.1-0.0-0.3-0.2-0.1-0.2-0.30.3-0.20.10.20.0-0.00.00.0-0.00.30.3
Locomotion in novel chamber post-restriction0.00.10.4-0.7-0.6-0.3-0.30.1-0.2-0.2-0.10.0-0.0-0.10.20.10.2-0.20.20.2-0.20.00.1
Fecal boli incidents, locomotor time 10.10.20.3-0.5-0.3-0.4-0.4-0.4-0.4-0.4-0.5-0.50.5-0.50.50.40.4-0.40.40.4-0.40.50.5
Change in fecal boli incidents, locomotor task0.20.22.5-1.6-0.6-0.3-0.3-0.2-0.2-0.3-0.2-0.20.2-0.10.20.10.2-0.20.20.2-0.20.0-0.0
Time >=10cm from walls, locomotor time 10.50.60.8-0.4-0.6-0.8-0.8-0.9-0.8-0.8-0.8-0.90.9-0.80.80.80.8-0.80.80.8-0.80.90.8
Bouts of movement, locomotor time 11.21.62.1-0.40.91.21.21.41.31.31.31.2-1.21.3-1.3-1.4-1.31.3-1.3-1.31.3-1.5-1.3
Total resting periods, locomotor time 12.63.03.8-0.01.41.71.71.91.81.81.81.7-1.71.8-1.8-1.9-1.81.8-1.8-1.81.8-2.0-1.9
Rest time, locomotor task time 10.50.71.0-0.60.60.80.80.90.90.80.90.8-0.80.9-0.8-1.0-0.90.9-0.9-0.90.9-1.0-0.9
Distance moved, locomotor task time 10.20.53.11.8-0.1-0.6-0.6-0.6-0.6-0.6-0.6-0.40.4-0.60.60.80.6-0.60.60.6-0.60.80.7
Vertical activity count, locomotor time 10.10.61.31.2-0.4-0.8-0.8-0.8-0.8-0.8-0.8-0.60.6-0.80.70.90.8-0.80.80.8-0.80.90.9
Time >=10cm from walls, locomotor time 20.61.72.70.9-0.6-1.3-1.3-1.3-1.3-1.2-1.4-1.31.3-1.41.31.51.2-1.21.21.2-1.21.61.7
Bouts of movement, locomotor time 20.10.43.1-1.8-0.20.40.40.50.50.40.50.3-0.30.5-0.4-0.6-0.40.4-0.4-0.40.4-0.7-0.8
Total resting periods, locomotor time 20.10.63.1-1.8-0.10.60.60.70.70.60.70.5-0.50.7-0.6-0.8-0.50.5-0.5-0.60.6-0.9-1.0
Rest time, locomotor task time 20.20.32.8-1.7-0.6-0.4-0.4-0.4-0.3-0.4-0.3-0.40.4-0.30.40.20.4-0.40.40.4-0.40.20.1
Distance moved, locomotor task time 21.72.37.32.71.71.41.41.51.41.41.41.6-1.61.4-1.5-1.3-1.41.4-1.4-1.41.4-1.2-1.2
Vertical activity count, locomotor time 20.00.10.80.90.30.20.20.30.20.20.20.3-0.30.2-0.2-0.1-0.20.2-0.2-0.20.2-0.10.0
Light reinforcement 10.52.02.90.51.31.51.51.71.51.41.51.7-1.71.5-1.3-1.5-1.41.4-1.4-1.41.4-1.5-1.5
Light reinforcement 21.02.23.21.01.81.51.61.51.51.51.51.5-1.51.5-1.5-1.4-1.51.5-1.5-1.51.5-1.3-1.4
Bone: marrow area0.20.52.31.50.0-0.4-0.4-0.7-0.6-0.5-0.7-0.70.7-0.70.60.80.6-0.60.60.6-0.60.90.9
Bone: maximum diameter0.00.00.40.60.40.20.20.10.10.20.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.1-0.1
Bone: maximum force2.65.15.82.42.32.42.42.32.32.32.32.3-2.32.3-2.2-2.2-2.22.2-2.2-2.22.2-2.2-2.2
Bone: maximum moment2.85.35.92.32.32.42.42.32.32.32.42.3-2.32.3-2.3-2.3-2.22.2-2.2-2.22.2-2.3-2.3
Mean time between licks in bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Mean num. licks in bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Cd content in liver0.10.10.3-0.1-0.2-0.3-0.3-0.4-0.4-0.3-0.4-0.50.5-0.40.40.40.4-0.40.40.4-0.40.40.4
Co content in liver0.00.00.30.60.10.10.0-0.1-0.1-0.0-0.1-0.20.2-0.10.00.10.0-0.00.00.0-0.00.10.1
Cu content in liver4.25.06.72.62.52.32.32.22.22.22.22.1-2.12.2-2.3-2.1-2.22.2-2.2-2.22.2-2.1-2.1
Fe content in liver1.01.22.6-1.6-1.4-1.1-1.1-1.0-1.0-1.1-1.0-1.01.0-1.01.11.01.2-1.21.21.2-1.20.90.8
K content in liver0.50.51.31.11.10.70.70.50.60.60.50.5-0.50.5-0.7-0.5-0.80.8-0.8-0.80.8-0.4-0.4
Mg content in liver0.10.10.20.40.1-0.2-0.2-0.3-0.3-0.3-0.3-0.30.3-0.30.30.40.3-0.30.30.3-0.30.40.3
Mn content in liver0.60.72.0-1.4-1.1-0.8-0.8-0.7-0.7-0.8-0.7-0.50.5-0.70.80.70.8-0.80.80.8-0.80.60.7
Na content in liver0.50.51.01.00.80.70.70.70.70.70.60.8-0.80.6-0.7-0.7-0.80.8-0.8-0.80.8-0.6-0.7
Rb content in liver0.00.00.40.60.10.30.20.10.10.10.20.2-0.20.2-0.1-0.1-0.10.1-0.1-0.10.1-0.1-0.3
Se content in liver0.10.10.6-0.8-0.4-0.2-0.2-0.3-0.3-0.3-0.2-0.40.4-0.20.30.30.4-0.40.40.4-0.40.20.2
Sr content in liver4.53.94.1-1.6-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.02.0-2.02.02.02.0-2.02.02.0-2.02.01.9
Zn content in liver0.70.92.11.51.30.91.00.80.80.90.80.6-0.60.8-0.9-0.8-1.01.0-1.0-1.01.0-0.7-0.9
Bone: minimum diameter0.71.31.71.31.31.31.31.11.11.21.11.1-1.11.1-1.1-1.1-1.11.1-1.1-1.11.1-1.0-1.0
Time in familiar zone, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in novel zone, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total zone transitions, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total locomotion distance, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in familiar zone, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in novel zone, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total zone transitions, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total locomotion distance, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Novel to familiar place preference ratio0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Novelty place preference0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in novel zone, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total zone transitions, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total locomotion distance, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intraocular pressure0.10.11.21.10.50.40.20.00.20.20.20.1-0.10.1-0.2-0.1-0.20.2-0.2-0.20.20.0-0.1
Delta distance traveled before/after self-admin0.00.00.10.2-0.1-0.2-0.2-0.2-0.1-0.2-0.1-0.00.0-0.20.10.20.2-0.20.20.2-0.20.20.3
Delta ambulatory time before/after self-admin0.20.40.5-0.3-0.6-0.7-0.7-0.7-0.7-0.6-0.6-0.60.6-0.60.60.70.6-0.60.60.6-0.60.70.7
Parametrial fat weight0.71.62.21.51.31.31.41.11.21.31.21.1-1.11.3-1.3-1.2-1.31.3-1.3-1.31.3-1.3-1.3
Pavlov. Cond. lever latency0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. magazine entry latency0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. change in total contacts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. index score0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. latency score0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. lever contacts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. magazine entry number0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. intertrial magazine entries0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. response bias0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. lever latency1.01.42.01.11.41.31.31.11.21.21.11.1-1.11.1-1.2-1.1-1.31.3-1.3-1.21.2-1.1-1.1
Pavlov. Cond. magazine entry latency1.31.95.3-2.3-1.8-1.4-1.4-1.2-1.2-1.3-1.2-1.21.2-1.21.31.11.4-1.41.41.4-1.41.01.0
Pavlov. Cond. change in total contacts0.10.20.7-0.9-0.6-0.5-0.5-0.4-0.4-0.4-0.4-0.40.4-0.40.40.30.4-0.40.40.4-0.40.30.3
Pavlov. Cond. index score0.81.31.8-1.2-1.3-1.2-1.2-1.1-1.1-1.1-1.1-1.11.1-1.11.11.11.2-1.21.21.2-1.21.01.0
Pavlov. Cond. latency score1.01.62.1-1.2-1.5-1.3-1.3-1.2-1.2-1.3-1.2-1.21.2-1.21.31.21.3-1.31.31.3-1.31.21.2
Pavlov. Cond. lever contacts1.01.52.1-1.3-1.5-1.3-1.3-1.1-1.2-1.2-1.1-1.11.1-1.11.21.11.3-1.31.31.3-1.31.11.1
Pavlov. Cond. magazine entry number0.40.50.70.80.80.80.80.70.70.70.70.7-0.70.7-0.7-0.6-0.70.7-0.7-0.70.7-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.30.60.8-0.6-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.80.80.80.9-0.90.90.9-0.90.80.8
Pavlov. Cond. lever-magazine prob. diff.0.50.81.3-1.1-1.1-1.0-1.0-0.8-0.9-0.9-0.8-0.80.8-0.80.90.80.9-0.90.90.9-0.90.80.8
Pavlov. Cond. response bias0.91.22.4-1.6-1.4-1.2-1.2-1.0-1.0-1.1-1.0-1.01.0-1.01.11.01.1-1.11.11.1-1.10.90.9
Time in closed arm before self-admin3.45.97.1-2.5-2.7-2.5-2.5-2.3-2.4-2.5-2.4-2.42.4-2.42.52.42.5-2.52.52.5-2.52.32.2
Time in closed arm after self-admin2.22.55.1-2.3-2.1-1.5-1.5-1.4-1.5-1.5-1.5-1.51.5-1.41.61.41.6-1.61.61.6-1.61.21.3
Time in open arm before self-admin4.95.96.61.52.52.52.52.42.42.52.52.4-2.42.5-2.5-2.5-2.62.6-2.6-2.52.5-2.4-2.4
Time in open arm after self-admin8.99.814.33.83.83.23.22.93.13.23.03.0-3.03.0-3.1-2.9-3.13.1-3.1-3.13.1-2.7-2.8
Bone: periosteal estimation0.10.32.41.60.80.60.60.40.40.50.40.4-0.40.4-0.4-0.3-0.30.3-0.3-0.40.4-0.3-0.3
Bone: periosteal perimeter0.30.60.91.01.00.90.90.80.80.80.80.8-0.80.8-0.7-0.8-0.70.7-0.7-0.70.7-0.7-0.7
Bone: post-yield work1.42.42.71.31.61.61.61.51.61.61.51.5-1.51.5-1.5-1.5-1.61.6-1.6-1.61.6-1.5-1.5
Progressive ratio test 1 active lever presses0.20.30.4-0.50.20.50.40.60.50.50.60.6-0.60.6-0.5-0.6-0.50.5-0.5-0.50.5-0.7-0.6
Progressive ratio test 1 breakpoint0.20.30.8-0.90.00.50.50.60.50.50.60.6-0.60.6-0.5-0.6-0.50.5-0.5-0.50.5-0.7-0.7
Progressive ratio test 1 inactive lever presses0.20.40.6-0.00.60.60.60.60.60.60.60.6-0.60.6-0.6-0.7-0.70.7-0.7-0.70.7-0.7-0.8
Progressive ratio test 2 active lever presses1.52.12.9-0.11.01.51.41.61.61.51.61.6-1.61.6-1.5-1.6-1.41.4-1.4-1.41.4-1.7-1.4
Progressive ratio test 2 breakpoint1.92.43.2-0.01.11.51.41.71.61.61.71.7-1.71.7-1.6-1.7-1.51.5-1.5-1.51.5-1.8-1.5
Progressive ratio test 2 inactive lever presses0.10.40.70.60.80.70.70.70.70.70.70.6-0.60.6-0.7-0.6-0.70.7-0.7-0.70.7-0.6-0.3
Incentive Sensitization - Responses1.13.13.90.41.51.81.72.01.91.81.81.9-1.91.8-1.8-1.9-1.81.8-1.8-1.81.8-2.0-1.5
Incentive Sensitization - Breakpoint1.43.24.00.51.51.81.72.01.91.81.91.9-1.91.9-1.8-1.9-1.81.8-1.8-1.81.8-2.0-1.5
Sum of active levers in priming session hrs 5-60.20.20.5-0.7-0.5-0.4-0.4-0.4-0.4-0.5-0.4-0.40.4-0.40.50.40.4-0.40.40.4-0.40.40.6
Progressive ratio0.10.31.41.20.70.40.50.40.50.50.40.4-0.40.4-0.5-0.4-0.50.5-0.5-0.50.5-0.3-0.4
Food seeking constrained by brief footshock0.40.50.80.20.70.70.70.70.70.70.70.8-0.80.7-0.7-0.8-0.70.7-0.7-0.70.7-0.7-0.9
Seeking ratio, punishment vs. effort0.20.53.6-1.9-1.0-0.5-0.6-0.5-0.6-0.6-0.5-0.50.5-0.50.60.40.6-0.60.60.6-0.60.40.3
Retroperitoneal fat weight0.52.24.51.72.11.61.61.21.41.61.41.2-1.21.4-1.5-1.3-1.51.5-1.5-1.51.5-1.3-1.4
Reaction time number correct1.24.35.11.72.02.12.02.22.12.12.12.2-2.22.1-2.1-2.1-2.12.1-2.1-2.12.1-2.1-2.3
Reaction time mean minus median0.10.51.00.6-0.2-0.6-0.6-1.0-0.7-0.6-0.8-1.01.0-0.80.60.80.6-0.60.60.6-0.60.70.8
Reaction time mean minus median AUC0.00.31.51.20.70.50.50.30.50.50.50.3-0.30.4-0.5-0.4-0.50.5-0.5-0.50.5-0.5-0.2
Reaction time num false alarms0.00.10.10.20.30.30.30.20.30.30.20.2-0.20.3-0.3-0.3-0.30.3-0.3-0.30.3-0.2-0.4
Reaction time num false alarms AUC0.20.40.50.30.60.70.60.50.60.60.60.5-0.50.6-0.6-0.6-0.60.6-0.6-0.60.6-0.6-0.7
Reaction time trials correct on left1.24.35.11.72.02.12.02.22.12.12.12.2-2.22.1-2.1-2.1-2.12.1-2.1-2.12.1-2.1-2.3
Reaction time trials on left1.24.25.01.62.02.02.02.12.12.02.12.2-2.22.1-2.1-2.0-2.02.0-2.0-2.02.0-2.1-2.2
Reaction time mean1.22.63.2-1.0-1.4-1.7-1.6-1.7-1.7-1.6-1.7-1.81.8-1.71.61.61.5-1.51.51.6-1.61.61.7
Reaction time mean AUC1.53.64.3-1.1-1.7-2.0-1.9-2.0-2.0-1.9-2.0-2.12.1-2.01.92.01.8-1.81.81.9-1.91.92.0
Median of all reaction times1.42.22.7-1.3-1.5-1.6-1.6-1.5-1.5-1.5-1.5-1.61.6-1.51.51.51.5-1.51.51.5-1.51.51.5
Reaction time omissions0.30.53.0-1.7-0.7-0.7-0.7-0.5-0.6-0.7-0.6-0.60.6-0.60.70.60.7-0.70.70.7-0.70.50.5
Reaction time false alarm rate0.00.10.2-0.3-0.2-0.2-0.2-0.4-0.2-0.2-0.3-0.40.4-0.30.30.20.2-0.20.20.2-0.20.30.2
Reaction time premature initiation rate0.91.41.90.61.11.21.21.31.21.21.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.2-1.3-1.4
Reaction time premature initiations1.44.15.11.41.92.02.02.12.02.02.12.1-2.12.1-2.1-2.0-2.02.0-2.0-2.02.0-2.1-2.2
Std. dev. reaction times0.62.13.1-0.6-1.0-1.5-1.4-1.7-1.5-1.4-1.6-1.81.8-1.61.41.61.3-1.31.31.4-1.41.51.6
Reaction time trials completed1.24.25.01.62.02.02.02.12.12.02.12.2-2.22.1-2.1-2.0-2.02.0-2.0-2.02.0-2.1-2.2
Reaction time trials AUC1.24.24.91.82.02.02.02.12.12.02.02.2-2.22.0-2.1-2.0-2.02.0-2.0-2.02.0-2.0-2.2
Run reversals in cocaine runway, females0.10.10.20.20.20.30.30.40.30.30.40.4-0.40.4-0.3-0.3-0.30.3-0.3-0.30.3-0.4-0.3
Run reversals in cocaine runway, males1.21.42.01.41.11.01.11.21.11.11.11.3-1.31.1-1.2-1.1-1.11.1-1.1-1.11.2-1.1-1.1
Latency to leave start box in cocaine runway3.04.24.7-1.0-1.9-2.1-2.1-2.2-2.1-2.1-2.1-2.12.1-2.12.12.12.1-2.12.12.1-2.12.22.1
Latency to leave start box in cocaine runway, F2.12.73.0-1.2-1.6-1.6-1.6-1.7-1.7-1.6-1.7-1.71.7-1.71.61.61.6-1.61.61.6-1.61.71.6
Latency to leave start box in cocaine runway, M2.82.73.0-0.7-1.5-1.6-1.7-1.7-1.7-1.7-1.7-1.61.6-1.71.71.71.7-1.71.71.7-1.71.71.7
Std. dev. time between licks in bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total sessions with >9 infusions0.91.11.9-0.20.71.11.01.11.11.11.11.1-1.11.2-1.1-1.2-1.11.1-1.1-1.01.0-1.2-1.4
Short access day 1 total inactive lever presses0.10.10.80.90.40.30.30.30.30.30.30.3-0.30.3-0.3-0.2-0.30.3-0.3-0.30.3-0.2-0.2
Short access day 10 total inactive lever presses0.10.91.1-0.7-0.8-1.0-1.0-0.9-1.0-1.0-1.0-0.90.9-1.00.91.00.9-0.90.90.9-0.91.01.0
Short access day 1 total infusions0.40.81.40.30.80.90.90.90.90.91.01.0-1.01.0-0.9-0.9-0.90.9-0.9-0.90.9-1.0-1.2
Short access day 10 total infusions1.72.93.50.51.41.71.71.81.81.71.81.8-1.81.8-1.7-1.8-1.71.7-1.7-1.71.7-1.9-1.8
Short access total infusions3.04.36.00.21.62.12.02.12.12.12.22.2-2.22.2-2.1-2.2-2.12.1-2.1-2.12.1-2.3-2.5
Short access day 1 locomotion0.30.50.70.70.70.70.60.60.70.70.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.70.7-0.7-0.8
Short access day 10 total locomotion0.20.72.1-1.5-1.0-0.9-0.9-0.8-0.8-0.8-0.8-0.80.8-0.80.80.70.8-0.80.80.8-0.80.70.8
Short access total locomotion0.20.30.5-0.40.20.50.50.50.50.50.50.5-0.50.5-0.5-0.6-0.50.5-0.5-0.50.5-0.6-0.7
One hour access (0.3 mA shock)1.01.25.4-2.30.10.90.91.21.00.91.11.1-1.11.1-0.9-1.2-0.90.9-0.9-0.90.9-1.3-1.2
Compulsive drug intake0.71.11.4-0.7-0.8-1.1-1.0-1.0-1.1-1.1-1.1-1.11.1-1.11.11.11.1-1.11.11.1-1.11.21.0
One hour access (shock baseline)0.82.13.2-1.20.71.41.31.61.51.41.61.6-1.61.6-1.4-1.6-1.41.4-1.4-1.41.4-1.8-1.6
Social response proportion0.70.91.61.31.01.11.00.80.91.00.90.8-0.80.9-0.9-0.9-0.90.9-0.9-0.90.9-0.7-0.9
Social responses1.01.32.20.40.71.31.31.31.21.21.21.2-1.21.2-1.1-1.2-1.11.1-1.1-1.11.1-1.4-1.5
Social time0.20.32.1-1.4-0.10.40.40.50.40.30.40.4-0.40.4-0.3-0.5-0.30.3-0.3-0.30.3-0.7-0.7
Soleus weight0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Bone: stiffness4.27.78.52.82.82.92.92.82.82.82.82.8-2.82.8-2.8-2.8-2.72.7-2.7-2.72.7-2.7-2.7
Tibialis anterior weight0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time to tail flick, vehicle, before self-admin0.00.00.7-0.8-0.40.10.00.1-0.0-0.00.0-0.10.10.00.0-0.10.1-0.10.10.1-0.1-0.2-0.0
Time to tail flick, vehicle, after self-admin0.10.10.50.70.30.30.20.40.30.30.30.4-0.40.3-0.3-0.2-0.30.3-0.3-0.30.3-0.3-0.4
Time to tail flick, test, before self-admin0.20.32.3-1.5-0.5-0.4-0.3-0.5-0.4-0.4-0.4-0.50.5-0.40.40.30.4-0.40.40.4-0.40.30.5
Time to tail flick, test, after self-admin0.60.61.0-0.0-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.80.80.80.8-0.80.80.8-0.80.81.0
Delta time to tail flick, vehicle, before/after SA0.10.10.91.00.2-0.0-0.00.10.00.0-0.00.2-0.2-0.0-0.10.1-0.10.1-0.1-0.10.10.1-0.0
Delta time to tail flick, test, before/after SA0.20.22.41.5-0.1-0.2-0.3-0.2-0.3-0.3-0.3-0.20.2-0.30.30.40.3-0.30.30.3-0.30.40.4
Tibia length0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Ambulatory time before self-admin0.20.50.7-0.30.60.80.80.80.70.70.70.7-0.70.7-0.7-0.8-0.70.7-0.7-0.70.7-0.8-0.8
Ambulatory time after self-admin0.10.20.3-0.6-0.5-0.3-0.4-0.5-0.4-0.4-0.4-0.30.3-0.40.40.40.5-0.50.50.4-0.40.40.5
Bone: tissue strength4.85.15.42.02.12.32.32.32.32.32.32.3-2.32.3-2.3-2.3-2.22.2-2.2-2.22.2-2.3-2.3
Total heroin consumption0.60.72.61.61.10.70.80.70.80.80.70.8-0.80.7-0.8-0.7-0.80.8-0.8-0.80.8-0.6-0.8
Bone: trabecular number4.38.010.00.62.22.92.83.12.92.83.13.1-3.13.1-2.9-3.0-2.82.8-2.8-2.82.8-3.2-3.2
Bone: trabecular spacing1.52.22.4-0.9-1.4-1.4-1.4-1.5-1.5-1.5-1.5-1.51.5-1.51.51.51.5-1.51.51.5-1.51.51.5
Bone: trabecular thickness3.85.35.81.82.42.32.32.32.32.32.32.3-2.32.3-2.3-2.3-2.42.4-2.4-2.42.4-2.3-2.3
Bone: trabecular tissue density0.00.10.30.5-0.0-0.0-0.0-0.2-0.2-0.1-0.2-0.20.2-0.20.20.20.2-0.20.20.2-0.20.20.2
Water consumed over 24 hours0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Number of responses in last shaping day0.10.11.2-1.1-0.7-0.3-0.3-0.2-0.2-0.3-0.2-0.20.2-0.20.30.10.3-0.30.30.3-0.30.0-0.0