LOC134485553

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC134485553 0.84 0.11 2.1e-06 0.04 0.06 0.06 0.03 8.1e-05 3.1e-07 2.3e-07 1.6e-04
2 IC gene expression LOC134485553 0.91 0.06 0.0e+00 0.33 0.38 0.38 0.35 2.0e-14 6.3e-17 3.4e-17 2.9e-15
3 OFC intron excision ratio chr2_1127100_1133017 0.2 0.18 5.9e-03 0.09 0.07 0.08 0.07 4.8e-03 9.4e-03 7.2e-03 8.0e-03
4 Brain gene expression LOC134485553 0.86 0.1 0.0e+00 0.21 0.2 0.2 0.2 5.0e-19 4.4e-18 1.0e-18 1.3e-18
5 PL intron excision ratio chr2_1133045_1133365 0.07 0.06 4.4e-07 0.06 0.06 0.06 0.06 3.4e-07 5.0e-07 4.9e-07 4.5e-07
6 Brain intron excision ratio chr2_1133452_1163297 0.04 0.04 2.9e-04 0.03 0.03 0.04 0.03 3.8e-04 4.1e-04 2.8e-04 4.4e-04
7 Brain intron excision ratio chr2_1133045_1133365 0.07 0.07 6.8e-06 0.05 0.05 0.05 0.05 1.4e-05 1.6e-05 1.1e-05 1.4e-05
8 OFC gene expression LOC134485553 0.62 0.24 1.8e-10 0.38 0.36 0.38 0.38 7.0e-10 1.5e-09 4.6e-10 6.4e-10
9 IC isoform ratio XR_010063670.1 0.07 0.07 9.3e-03 0.02 0.02 0.01 0.01 4.1e-02 6.2e-02 1.0e-01 8.6e-02
10 IC isoform ratio XR_010063671.1 0.07 0.07 7.9e-03 0.02 0.02 0.02 0.01 4.1e-02 6.5e-02 6.3e-02 9.1e-02
11 pVTA mRNA stability LOC134485553 0.04 0.04 3.1e-03 0.03 0.03 0.03 0.03 3.3e-03 2.9e-03 3.8e-03 3.9e-03
12 Adipose gene expression LOC134485553 0.19 0.15 0.0e+00 0.13 0.12 0.13 0.13 7.8e-14 9.3e-14 7.7e-14 7.7e-14
13 Brain mRNA stability LOC134485553 0.18 0.13 1.7e-16 0.17 0.17 0.17 0.17 9.8e-16 5.6e-16 4.9e-16 6.5e-16
14 pVTA isoform ratio XR_010063670.1 0.09 0.12 1.1e-04 0.05 0.05 0.04 0.05 8.3e-05 8.6e-05 2.2e-04 7.4e-05
15 IC intron excision ratio chr2_1133045_1133365 0.09 0.08 3.1e-03 0.04 0.04 0.04 0.04 5.9e-03 8.2e-03 7.9e-03 8.2e-03
16 pVTA isoform ratio XR_010063671.1 0.09 0.12 8.7e-05 0.05 0.05 0.04 0.05 6.5e-05 7.2e-05 2.0e-04 6.7e-05
17 Brain isoform ratio XR_010063670.1 0.03 0.03 4.7e-03 0.02 0.02 0.02 0.02 3.2e-03 3.0e-03 3.2e-03 2.7e-03
18 Brain isoform ratio XR_010063671.1 0.03 0.03 5.5e-03 0.02 0.02 0.02 0.02 3.8e-03 3.5e-03 3.7e-03 3.2e-03
19 NAcc gene expression LOC134485553 0.02 0.02 4.5e-03 0.01 0.01 0 0.01 4.8e-03 9.8e-03 6.6e-02 8.1e-03
20 OFC isoform ratio XR_010063671.1 0.18 0.17 9.3e-03 0.06 0.05 0.05 0.05 1.4e-02 2.4e-02 2.2e-02 2.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density7.813.515.0-2.5-3.3-3.7-3.7-3.8-3.7-3.7-3.8-3.83.83.8-3.73.8-3.6-3.63.6-3.73.73.93.9
Area under the delay curve0.10.10.20.30.30.40.40.40.30.40.40.3-0.3-0.40.3-0.40.40.4-0.40.4-0.4-0.4-0.3
BMI with tail1.75.810.3-3.2-3.0-2.4-2.5-2.2-2.3-2.4-2.2-2.22.22.2-2.42.2-2.4-2.42.4-2.42.42.12.0
BMI without tail2.16.318.7-4.3-3.7-2.5-2.6-2.0-2.3-2.5-2.1-2.02.02.1-2.42.0-2.5-2.52.5-2.52.51.81.8
Body weight1.66.918.8-4.3-3.8-2.6-2.7-2.1-2.4-2.6-2.3-2.22.22.2-2.62.2-2.7-2.72.7-2.62.61.91.9
Weight adjusted by age2.23.35.4-2.3-1.9-1.9-1.8-1.8-1.8-1.8-1.7-1.81.81.7-1.81.7-1.8-1.81.8-1.81.81.71.7
Bone surface1.12.12.3-1.2-1.3-1.5-1.5-1.5-1.5-1.4-1.5-1.51.51.5-1.41.5-1.4-1.41.4-1.41.41.51.5
Bone volume4.07.17.6-2.0-2.5-2.7-2.7-2.8-2.7-2.7-2.8-2.82.82.8-2.72.7-2.6-2.62.6-2.72.72.82.8
Breakpoint value in progressive ratio session0.10.10.30.10.50.40.50.30.40.40.40.2-0.2-0.40.4-0.40.40.4-0.40.4-0.4-0.4-0.2
Number of licking bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Context. condit. distance diff. score0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving bouts, day 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving duration, day 30.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving bouts, day 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Stereotopy head waving duration, day 70.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, session 80.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion distance, session 80.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Degree of sensitization distance0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Degree of sensitization stereotypy0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Conditioned locomotion2.22.53.0-0.7-1.3-1.7-1.7-1.7-1.6-1.6-1.7-1.71.71.7-1.61.7-1.5-1.51.5-1.51.51.71.7
Cocaine response after cond. corrected3.03.64.21.51.62.01.92.02.01.92.02.0-2.0-2.01.9-2.01.81.8-1.81.8-1.8-2.0-2.0
Cocaine response after cond. not corrected1.61.92.40.81.01.41.41.51.51.41.51.5-1.5-1.51.3-1.51.21.2-1.21.2-1.2-1.6-1.6
Cocaine response before conditioning0.40.51.1-1.1-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.70.70.7-0.70.7-0.7-0.70.7-0.70.70.60.6
Saline control response1.11.41.7-0.8-0.9-1.2-1.2-1.3-1.2-1.2-1.3-1.31.31.3-1.21.3-1.2-1.21.2-1.21.21.31.3
Bone: connectivity density3.75.77.5-0.7-1.7-2.4-2.3-2.6-2.5-2.4-2.6-2.62.62.6-2.42.6-2.3-2.32.3-2.32.32.72.7
Bone: cortical apparent density0.10.10.2-0.1-0.3-0.4-0.4-0.4-0.4-0.3-0.4-0.40.40.4-0.40.4-0.4-0.40.4-0.40.40.40.4
Bone: cortical area2.94.45.1-1.6-2.0-2.3-2.2-2.2-2.2-2.2-2.2-2.22.22.2-2.12.2-2.0-2.02.0-2.02.02.22.2
Bone: cortical porosity1.11.21.6-1.1-0.9-1.3-1.2-1.2-1.1-1.1-1.2-1.21.21.2-1.11.1-0.9-0.90.9-1.01.01.21.2
Bone: cortical porosity2.52.73.4-1.6-1.4-1.8-1.7-1.7-1.7-1.6-1.8-1.71.71.7-1.61.7-1.5-1.51.5-1.51.51.71.7
Bone: cortical thickness5.69.310.5-1.8-2.7-3.2-3.1-3.2-3.1-3.1-3.2-3.23.23.2-3.03.2-3.0-3.03.0-3.03.03.23.2
Bone: cortical thickness0.30.30.5-0.4-0.7-0.6-0.6-0.5-0.6-0.6-0.5-0.50.50.5-0.60.6-0.6-0.60.6-0.60.60.60.6
Bone: cortical tissue density0.00.00.00.1-0.0-0.1-0.0-0.1-0.0-0.0-0.1-0.10.10.1-0.10.1-0.1-0.10.1-0.10.10.10.1
Condit. Reinf. active minus inactive responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. active-inactive response ratio0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. active responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. inactive responses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Incentive salience index mean0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. lever presses0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Condit. Reinf. active minus inactive responses0.70.91.1-0.6-0.8-0.9-0.9-1.0-1.0-1.0-1.0-1.01.01.0-1.01.0-1.0-1.01.0-1.01.01.01.0
Condit. Reinf. active-inactive response ratio1.21.41.5-1.0-1.2-1.1-1.1-1.2-1.2-1.2-1.2-1.21.21.2-1.21.2-1.2-1.21.2-1.21.21.21.2
Condit. Reinf. active responses0.20.30.4-0.0-0.1-0.4-0.4-0.6-0.5-0.5-0.6-0.60.60.6-0.50.6-0.5-0.50.5-0.50.50.70.7
Condit. Reinf. inactive responses0.70.91.81.21.31.01.00.80.91.00.90.8-0.8-0.80.9-0.81.01.0-1.01.0-1.0-0.8-0.8
Condit. Reinf. lever presses0.20.30.40.10.60.60.60.50.50.50.50.5-0.5-0.50.5-0.50.60.6-0.60.5-0.5-0.5-0.5
Condit. Reinf. lever reinforcers received0.10.10.20.20.1-0.1-0.1-0.3-0.3-0.2-0.3-0.30.30.3-0.30.4-0.2-0.20.2-0.20.20.40.4
Conditioned reinforcement - actives0.00.10.20.30.20.20.40.30.20.20.20.2-0.2-0.20.2-0.20.20.2-0.20.2-0.2-0.2-0.4
Conditioned reinforcement - inactives0.00.00.1-0.3-0.20.00.10.10.10.00.10.1-0.1-0.10.1-0.10.10.1-0.10.1-0.1-0.2-0.1
Conditioned locomotion0.00.00.10.30.30.10.20.00.00.10.0-0.00.0-0.00.00.00.00.0-0.00.0-0.00.1-0.0
Patch foraging indifference point 0 sec2.75.16.6-2.6-2.3-2.3-2.3-2.3-2.3-2.3-2.2-2.32.32.2-2.22.2-2.2-2.22.2-2.22.22.22.1
Patch foraging indifference point AUC0.30.51.71.31.10.70.60.30.50.70.50.4-0.4-0.50.7-0.50.80.8-0.80.7-0.7-0.4-0.4
Delay disc. indifference point, 0s delay0.40.50.7-0.20.30.60.60.70.70.60.70.8-0.8-0.70.6-0.80.60.6-0.60.7-0.7-0.8-0.8
Delay disc. indifference point, 16s delay0.00.00.50.70.30.20.20.10.10.20.10.0-0.0-0.10.1-0.10.20.2-0.20.2-0.2-0.10.1
Delay disc. indifference point, 2s delay0.20.20.80.90.60.40.40.30.40.40.40.4-0.4-0.40.4-0.40.40.4-0.40.4-0.4-0.3-0.3
Delay disc. indifference point, 24s delay0.10.10.9-1.0-0.5-0.0-0.00.10.0-0.00.1-0.00.0-0.1-0.0-0.2-0.0-0.00.0-0.00.0-0.3-0.1
Delay disc. indifference point, 4s delay0.91.01.30.60.81.01.01.11.01.01.01.0-1.0-1.01.0-1.01.01.0-1.01.0-1.0-1.1-1.0
Delay disc. indifference point, 8s delay0.00.00.2-0.4-0.20.00.00.20.10.00.10.1-0.1-0.10.0-0.10.00.0-0.00.0-0.0-0.2-0.1
Indifference point function ln k3.45.99.1-2.7-3.0-2.6-2.5-2.1-2.4-2.5-2.3-2.22.22.3-2.52.3-2.6-2.62.6-2.52.52.02.2
Indifference point function log k3.45.99.1-2.7-3.0-2.6-2.5-2.1-2.4-2.5-2.3-2.22.22.3-2.52.3-2.6-2.62.6-2.52.52.02.2
Patch foraging total patch changes 0 sec2.54.86.7-2.6-2.3-2.3-2.3-2.2-2.2-2.2-2.2-2.22.22.1-2.12.1-2.1-2.12.1-2.12.12.12.1
Patch foraging total patch changes 12 sec0.10.20.30.10.1-0.4-0.5-0.6-0.4-0.3-0.5-0.60.60.5-0.20.4-0.1-0.10.1-0.20.20.60.6
Patch foraging total patch changes 18 sec0.20.20.60.20.3-0.3-0.4-0.7-0.5-0.4-0.5-0.70.70.5-0.40.5-0.3-0.30.3-0.30.30.80.7
Patch foraging total patch changes 24 sec1.22.03.1-0.7-1.0-1.3-1.4-1.8-1.5-1.4-1.4-1.71.71.4-1.31.5-1.3-1.31.3-1.31.31.61.5
Patch foraging total patch changes 6 sec0.20.31.0-1.0-0.3-0.7-0.7-0.7-0.6-0.5-0.6-0.70.70.6-0.40.5-0.4-0.40.4-0.40.40.80.6
Patch foraging time to switch 0 sec0.71.41.70.71.21.21.31.31.31.21.21.3-1.3-1.21.1-1.31.11.1-1.11.2-1.2-1.2-1.2
Patch foraging water rate 0 sec5.912.418.4-4.3-4.0-3.5-3.6-3.4-3.5-3.5-3.4-3.43.43.4-3.53.3-3.5-3.53.5-3.53.53.23.1
Patch foraging water rate 12 sec1.83.74.3-2.1-1.9-2.0-2.0-2.0-1.9-1.9-1.9-1.91.91.9-1.91.9-1.9-1.91.9-1.91.92.01.8
Patch foraging water rate 18 sec3.96.06.9-1.7-2.5-2.6-2.6-2.5-2.5-2.5-2.4-2.42.42.4-2.42.5-2.5-2.52.5-2.52.52.52.5
Patch foraging water rate 24 sec4.05.66.8-2.2-2.6-2.5-2.5-2.4-2.4-2.4-2.3-2.42.42.3-2.42.3-2.4-2.42.4-2.42.42.32.4
Patch foraging water rate 6 sec2.63.84.2-2.1-1.9-1.9-2.0-1.8-1.9-2.0-1.9-1.81.81.9-1.91.9-2.0-2.02.0-2.02.01.91.9
Seeking ratio, delayed vs. immediate footshock0.30.30.5-0.00.20.50.50.70.60.50.70.7-0.7-0.70.6-0.60.50.5-0.50.5-0.5-0.7-0.6
Distance traveled before self-admin0.81.01.40.0-0.8-1.2-1.1-1.1-1.1-1.1-1.1-0.90.91.1-1.01.1-1.0-1.01.0-1.01.01.11.2
Distance traveled after self-admin0.40.50.80.0-0.4-0.8-0.7-0.7-0.8-0.7-0.8-0.80.80.8-0.70.8-0.6-0.60.6-0.70.70.90.7
Extensor digitorum longus weight0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Bone: elastic displacement0.40.50.91.00.80.60.70.70.70.70.60.7-0.7-0.70.7-0.70.70.7-0.70.7-0.7-0.6-0.6
Bone: elastic work1.11.51.7-0.6-1.1-1.3-1.3-1.3-1.2-1.2-1.3-1.31.31.3-1.21.3-1.2-1.21.2-1.21.21.31.3
Bone: endosteal estimation0.20.51.0-1.00.00.50.50.70.70.50.70.7-0.7-0.70.6-0.80.60.6-0.60.6-0.6-0.9-0.9
Bone: endosteal perimeter0.40.91.10.20.60.80.81.01.00.91.01.0-1.0-1.01.0-1.01.01.0-1.01.0-1.0-1.1-1.1
Epididymis fat weight1.65.46.2-1.1-2.2-2.5-2.4-2.5-2.4-2.3-2.4-2.42.42.4-2.32.4-2.3-2.32.3-2.32.32.42.5
Delta time in closed arm before/after self-admin1.11.01.5-0.6-0.6-1.0-1.0-1.1-1.1-1.0-1.1-1.11.11.1-1.01.1-1.0-1.01.0-1.01.01.21.0
Delta time in open arm before/after self-admin3.53.49.6-3.1-2.6-1.9-1.8-1.5-1.7-1.8-1.6-1.81.81.6-1.81.5-1.7-1.71.7-1.71.71.31.6
Diff in mean of infusions in LGA sessions0.40.51.00.1-0.3-0.6-0.6-1.0-0.8-0.7-0.8-0.80.80.8-0.70.8-0.6-0.60.6-0.70.70.90.9
Delay discount exponential model param0.10.10.1-0.3-0.2-0.3-0.3-0.4-0.3-0.3-0.3-0.20.20.3-0.30.3-0.3-0.30.3-0.30.30.30.3
Extinction: sum of active levers before priming0.10.11.6-1.3-0.4-0.1-0.00.10.0-0.00.10.0-0.0-0.0-0.0-0.1-0.0-0.00.0-0.00.0-0.1-0.1
Active lever presses in extinction session 60.00.00.1-0.10.0-0.1-0.2-0.3-0.2-0.1-0.2-0.30.30.2-0.20.2-0.1-0.10.1-0.20.20.30.2
Bone: final force1.72.75.4-2.3-1.8-1.8-1.8-1.6-1.6-1.7-1.7-1.61.61.6-1.61.5-1.5-1.51.5-1.51.51.51.5
Bone: final moment1.72.75.0-2.2-1.8-1.8-1.8-1.6-1.6-1.7-1.7-1.61.61.7-1.61.5-1.5-1.51.5-1.51.51.51.5
Food consumed during 24 hour testing period0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Glucose0.10.21.2-0.8-1.1-0.4-0.5-0.1-0.3-0.5-0.2-0.00.00.2-0.40.3-0.5-0.50.5-0.50.50.00.1
Heart weight1.11.63.6-1.6-1.9-1.3-1.3-1.0-1.2-1.3-1.2-1.11.11.2-1.31.1-1.3-1.31.3-1.31.31.01.0
Delay discount hyperbolic model param0.20.20.3-0.5-0.4-0.5-0.5-0.5-0.4-0.5-0.5-0.40.40.4-0.40.5-0.5-0.50.5-0.50.50.50.4
Intermittent access intake day 1-15 change0.10.34.02.00.80.20.30.20.20.20.10.2-0.2-0.10.3-0.00.30.3-0.30.3-0.30.10.0
Intermittent access intake escalation0.10.22.41.50.3-0.2-0.1-0.2-0.2-0.1-0.3-0.20.20.3-0.10.3-0.1-0.10.1-0.10.10.40.4
Intermittent access intake escalation 20.20.23.51.90.70.20.30.10.20.20.10.1-0.1-0.10.2-0.10.30.3-0.30.3-0.30.0-0.1
Intermitt. access day 1 inactive lever presses0.41.61.81.11.11.31.21.31.31.31.31.3-1.3-1.31.2-1.31.21.2-1.21.3-1.3-1.3-1.2
Intermitt. access day 15 inactive lever presses0.71.41.90.20.81.21.11.31.21.21.31.2-1.2-1.31.2-1.31.21.2-1.21.2-1.2-1.4-1.3
Intermitt. access escalation Index0.20.20.50.1-0.2-0.5-0.4-0.7-0.5-0.5-0.6-0.60.60.6-0.40.6-0.4-0.40.4-0.40.40.60.7
Intermittent access day 1 total infusions1.52.42.6-1.2-1.4-1.6-1.5-1.6-1.6-1.6-1.6-1.61.61.6-1.61.6-1.6-1.61.6-1.61.61.61.5
Intermittent access day 15 total infusions1.31.92.90.4-0.7-1.4-1.3-1.5-1.5-1.4-1.5-1.51.51.5-1.41.6-1.3-1.31.3-1.31.31.71.5
Intermittent access terminal intake (last 3 days)0.91.22.20.8-0.3-1.1-1.0-1.2-1.2-1.1-1.2-1.21.21.3-1.11.3-1.0-1.01.0-1.01.01.51.3
Intermittent access total infusions2.12.43.60.1-0.9-1.6-1.5-1.7-1.7-1.6-1.7-1.71.71.7-1.61.8-1.5-1.51.5-1.51.51.91.7
Intermittent access day 1 locomotion0.70.91.1-0.7-0.8-0.9-0.8-1.0-1.0-1.0-1.0-1.01.01.0-1.01.0-1.0-1.01.0-1.01.01.10.9
Intermittent access day 15 total locomotion1.32.43.60.1-0.8-1.5-1.5-1.7-1.6-1.5-1.6-1.61.61.6-1.51.7-1.5-1.51.5-1.51.51.91.7
Intermittent access total locomotion1.41.72.5-0.2-0.8-1.3-1.2-1.4-1.4-1.3-1.4-1.41.41.4-1.31.5-1.3-1.31.3-1.31.31.61.3
Intermittent access standard deviation0.30.71.00.4-0.6-0.9-0.9-0.9-0.9-0.8-0.9-0.90.90.9-0.81.0-0.8-0.80.8-0.80.81.00.9
Left kidney weight3.415.927.7-5.3-5.1-3.9-4.0-3.6-3.9-4.0-3.7-3.63.63.7-4.03.7-4.1-4.14.1-4.14.13.43.3
Right kidney weight2.410.724.0-4.9-4.3-3.2-3.2-2.9-3.1-3.3-3.0-2.92.93.0-3.32.9-3.4-3.43.4-3.33.32.72.6
Cocaine induced anxiety0.30.40.91.00.70.60.60.60.60.60.60.5-0.5-0.60.6-0.60.60.6-0.60.6-0.6-0.5-0.6
Post-drug Anxiety0.30.31.31.20.70.50.50.50.50.50.40.4-0.4-0.40.5-0.40.50.5-0.50.5-0.5-0.4-0.4
Baseline Anxiety0.10.20.40.0-0.2-0.4-0.4-0.4-0.4-0.4-0.4-0.40.40.4-0.40.5-0.4-0.40.4-0.40.40.50.6
Tail length0.62.59.6-3.1-2.7-1.5-1.5-1.1-1.4-1.5-1.2-1.11.11.2-1.51.2-1.6-1.61.6-1.61.60.80.9
Length with tail0.52.17.9-2.8-2.4-1.4-1.4-0.9-1.3-1.4-1.1-1.01.01.1-1.41.1-1.5-1.51.5-1.41.40.80.8
Length without tail0.10.20.3-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.40.40.5-0.50.5-0.5-0.50.5-0.50.50.50.4
Times rat made contact with spout0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Lifetime Intake2.83.44.7-0.1-1.2-1.8-1.8-2.0-1.9-1.8-2.0-2.02.02.0-1.92.1-1.8-1.81.8-1.81.82.22.1
Liver weight, left0.00.00.2-0.00.40.00.0-0.0-0.00.0-0.0-0.00.00.00.10.00.20.2-0.20.1-0.10.30.3
Liver weight, right1.11.92.71.61.71.31.31.31.31.41.31.4-1.4-1.31.4-1.31.51.5-1.51.4-1.4-1.3-1.0
Locomotor activity0.30.50.90.0-0.2-0.7-0.7-0.8-0.7-0.7-0.8-0.80.80.8-0.70.8-0.7-0.70.7-0.70.70.90.9
Locomotor testing distance0.91.64.32.11.81.11.21.01.21.21.11.1-1.1-1.11.3-1.01.21.2-1.21.2-1.2-1.0-1.0
Locomotor testing rearing0.20.53.61.91.20.50.60.30.50.60.40.4-0.4-0.40.6-0.30.60.6-0.60.6-0.6-0.3-0.2
Locomotion in novel chamber0.10.10.5-0.7-0.40.10.00.30.20.10.20.3-0.3-0.20.1-0.20.00.0-0.00.0-0.0-0.3-0.3
Locomotion in novel chamber post-restriction0.00.10.40.60.60.30.3-0.10.20.20.1-0.00.0-0.10.2-0.10.20.2-0.20.2-0.2-0.0-0.1
Fecal boli incidents, locomotor time 10.10.20.40.60.30.40.40.40.40.40.50.5-0.5-0.50.5-0.40.40.4-0.40.4-0.4-0.5-0.5
Change in fecal boli incidents, locomotor task0.20.21.81.30.60.30.30.20.20.30.20.2-0.2-0.10.2-0.10.20.2-0.20.2-0.2-0.00.0
Time >=10cm from walls, locomotor time 10.60.60.80.60.60.80.80.90.80.80.80.9-0.9-0.80.8-0.80.80.8-0.80.8-0.8-0.9-0.8
Bouts of movement, locomotor time 11.41.62.1-0.0-0.9-1.2-1.2-1.4-1.3-1.3-1.3-1.21.21.3-1.31.4-1.3-1.31.3-1.31.31.51.3
Total resting periods, locomotor time 12.73.03.8-0.4-1.4-1.7-1.7-1.9-1.8-1.8-1.8-1.71.71.8-1.81.9-1.8-1.81.8-1.81.82.01.9
Rest time, locomotor task time 10.60.71.00.3-0.6-0.8-0.8-0.9-0.9-0.8-0.9-0.80.80.9-0.81.0-0.9-0.90.9-0.90.91.00.9
Distance moved, locomotor task time 10.30.41.8-1.30.10.60.60.60.60.60.60.4-0.4-0.60.6-0.80.60.6-0.60.6-0.6-0.8-0.7
Vertical activity count, locomotor time 10.30.60.9-0.80.40.80.80.80.80.80.80.6-0.6-0.80.7-0.90.80.8-0.80.8-0.8-0.9-0.9
Time >=10cm from walls, locomotor time 21.11.62.7-0.40.61.31.31.31.31.21.41.3-1.3-1.41.3-1.51.21.2-1.21.2-1.2-1.6-1.7
Bouts of movement, locomotor time 20.20.31.61.30.2-0.4-0.4-0.5-0.5-0.4-0.5-0.30.30.5-0.40.6-0.4-0.40.4-0.40.40.70.8
Total resting periods, locomotor time 20.30.51.41.20.1-0.6-0.6-0.7-0.7-0.6-0.7-0.50.50.7-0.60.8-0.5-0.50.5-0.60.60.91.0
Rest time, locomotor task time 20.20.22.21.50.60.40.40.40.30.40.30.4-0.4-0.30.4-0.20.40.4-0.40.4-0.4-0.2-0.1
Distance moved, locomotor task time 21.92.36.6-2.6-1.7-1.4-1.4-1.5-1.4-1.4-1.4-1.61.61.4-1.51.3-1.4-1.41.4-1.41.41.21.2
Vertical activity count, locomotor time 20.10.10.7-0.9-0.3-0.2-0.2-0.3-0.2-0.2-0.2-0.30.30.2-0.20.1-0.2-0.20.2-0.20.20.1-0.0
Light reinforcement 10.82.12.9-0.9-1.3-1.5-1.5-1.7-1.5-1.4-1.5-1.71.71.5-1.31.5-1.4-1.41.4-1.41.41.51.5
Light reinforcement 21.42.23.2-1.2-1.8-1.5-1.6-1.5-1.5-1.5-1.5-1.51.51.5-1.51.4-1.5-1.51.5-1.51.51.31.4
Bone: marrow area0.20.41.1-1.1-0.00.40.40.70.60.50.70.7-0.7-0.70.6-0.80.60.6-0.60.6-0.6-0.9-0.9
Bone: maximum diameter0.00.00.3-0.5-0.4-0.2-0.2-0.1-0.1-0.2-0.1-0.10.10.1-0.10.1-0.1-0.10.1-0.10.10.10.1
Bone: maximum force2.95.26.2-2.5-2.3-2.4-2.4-2.3-2.3-2.3-2.3-2.32.32.3-2.22.2-2.2-2.22.2-2.22.22.22.2
Bone: maximum moment3.05.35.9-2.4-2.3-2.4-2.4-2.3-2.3-2.3-2.4-2.32.32.3-2.32.3-2.2-2.22.2-2.22.22.32.3
Mean time between licks in bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Mean num. licks in bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Cd content in liver0.10.10.30.20.20.30.30.40.40.30.40.5-0.5-0.40.4-0.40.40.4-0.40.4-0.4-0.4-0.4
Co content in liver0.00.00.2-0.4-0.1-0.1-0.00.10.10.00.10.2-0.2-0.10.0-0.10.00.0-0.00.0-0.0-0.1-0.1
Cu content in liver4.25.07.0-2.6-2.5-2.3-2.3-2.2-2.2-2.2-2.2-2.12.12.2-2.32.1-2.2-2.22.2-2.22.22.12.1
Fe content in liver1.01.22.51.61.41.11.11.01.01.11.01.0-1.0-1.01.1-1.01.21.2-1.21.2-1.2-0.9-0.8
K content in liver0.50.51.2-1.1-1.1-0.7-0.7-0.5-0.6-0.6-0.5-0.50.50.5-0.70.5-0.8-0.80.8-0.80.80.40.4
Mg content in liver0.10.10.2-0.3-0.10.20.20.30.30.30.30.3-0.3-0.30.3-0.40.30.3-0.30.3-0.3-0.4-0.3
Mn content in liver0.60.61.41.21.10.80.80.70.70.80.70.5-0.5-0.70.8-0.70.80.8-0.80.8-0.8-0.6-0.7
Na content in liver0.50.50.9-0.9-0.8-0.7-0.7-0.7-0.7-0.7-0.6-0.80.80.6-0.70.7-0.8-0.80.8-0.80.80.60.7
Rb content in liver0.00.00.3-0.5-0.1-0.3-0.2-0.1-0.1-0.1-0.2-0.20.20.2-0.10.1-0.1-0.10.1-0.10.10.10.3
Se content in liver0.10.10.40.70.40.20.20.30.30.30.20.4-0.4-0.20.3-0.30.40.4-0.40.4-0.4-0.2-0.2
Sr content in liver4.53.94.11.72.02.02.02.02.02.02.02.0-2.0-2.02.0-2.02.02.0-2.02.0-2.0-2.0-1.9
Zn content in liver0.80.81.8-1.3-1.3-0.9-1.0-0.8-0.8-0.9-0.8-0.60.60.8-0.90.8-1.0-1.01.0-1.01.00.70.9
Bone: minimum diameter0.71.31.7-1.3-1.3-1.3-1.3-1.1-1.1-1.2-1.1-1.11.11.1-1.11.1-1.1-1.11.1-1.11.11.01.0
Time in familiar zone, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in novel zone, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total zone transitions, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total locomotion distance, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, hab. session 10.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in familiar zone, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in novel zone, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total zone transitions, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total locomotion distance, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, hab. session 20.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Novel to familiar place preference ratio0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Novelty place preference0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time in novel zone, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total zone transitions, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total locomotion distance, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Locomotion velocity, NPP test0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Intraocular pressure0.10.10.8-0.9-0.5-0.4-0.2-0.0-0.2-0.2-0.2-0.10.10.1-0.20.1-0.2-0.20.2-0.20.2-0.00.1
Delta distance traveled before/after self-admin0.00.00.1-0.20.10.20.20.20.10.20.10.0-0.0-0.20.1-0.20.20.2-0.20.2-0.2-0.2-0.3
Delta ambulatory time before/after self-admin0.30.40.50.40.60.70.70.70.70.60.60.6-0.6-0.60.6-0.70.60.6-0.60.6-0.6-0.7-0.7
Parametrial fat weight0.71.62.1-1.4-1.3-1.3-1.4-1.1-1.2-1.3-1.2-1.11.11.3-1.31.2-1.3-1.31.3-1.31.31.31.3
Pavlov. Cond. lever latency0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. magazine entry latency0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. change in total contacts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. index score0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. latency score0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. lever contacts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. magazine entry number0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. intertrial magazine entries0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. response bias0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Pavlov. Cond. lever latency1.11.42.0-1.1-1.4-1.3-1.3-1.1-1.2-1.2-1.1-1.11.11.1-1.21.1-1.3-1.31.3-1.21.21.11.1
Pavlov. Cond. magazine entry latency1.51.84.72.21.81.41.41.21.21.31.21.2-1.2-1.21.3-1.11.41.4-1.41.4-1.4-1.0-1.0
Pavlov. Cond. change in total contacts0.10.20.60.80.60.50.50.40.40.40.40.4-0.4-0.40.4-0.30.40.4-0.40.4-0.4-0.3-0.3
Pavlov. Cond. index score1.01.31.81.31.31.21.21.11.11.11.11.1-1.1-1.11.1-1.11.21.2-1.21.2-1.2-1.0-1.0
Pavlov. Cond. latency score1.21.62.11.31.51.31.31.21.21.31.21.2-1.2-1.21.3-1.21.31.3-1.31.3-1.3-1.2-1.2
Pavlov. Cond. lever contacts1.11.52.11.31.51.31.31.11.21.21.11.1-1.1-1.11.2-1.11.31.3-1.31.3-1.3-1.1-1.1
Pavlov. Cond. magazine entry number0.40.50.7-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.70.70.7-0.70.6-0.7-0.70.7-0.70.70.60.6
Pavlov. Cond. intertrial magazine entries0.40.60.80.70.90.80.80.80.80.80.80.8-0.8-0.80.8-0.80.90.9-0.90.9-0.9-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.60.81.31.11.11.01.00.80.90.90.80.8-0.8-0.80.9-0.80.90.9-0.90.9-0.9-0.8-0.8
Pavlov. Cond. response bias0.91.22.21.51.41.21.21.01.01.11.01.0-1.0-1.01.1-1.01.11.1-1.11.1-1.1-0.9-0.9
Time in closed arm before self-admin4.76.07.12.62.72.52.52.32.42.52.42.4-2.4-2.42.5-2.42.52.5-2.52.5-2.5-2.3-2.2
Time in closed arm after self-admin2.32.44.82.22.11.51.51.41.51.51.51.5-1.5-1.41.6-1.41.61.6-1.61.6-1.6-1.2-1.3
Time in open arm before self-admin5.56.06.6-1.8-2.5-2.5-2.5-2.4-2.4-2.5-2.5-2.42.42.5-2.52.5-2.6-2.62.6-2.52.52.42.4
Time in open arm after self-admin8.99.814.3-3.8-3.8-3.2-3.2-2.9-3.1-3.2-3.0-3.03.03.0-3.12.9-3.1-3.13.1-3.13.12.72.8
Bone: periosteal estimation0.10.31.8-1.3-0.8-0.6-0.6-0.4-0.4-0.5-0.4-0.40.40.4-0.40.3-0.3-0.30.3-0.40.40.30.3
Bone: periosteal perimeter0.40.60.9-1.0-1.0-0.9-0.9-0.8-0.8-0.8-0.8-0.80.80.8-0.70.8-0.7-0.70.7-0.70.70.70.7
Bone: post-yield work1.62.42.7-1.5-1.6-1.6-1.6-1.5-1.6-1.6-1.5-1.51.51.5-1.51.5-1.6-1.61.6-1.61.61.51.5
Progressive ratio test 1 active lever presses0.20.30.40.2-0.2-0.5-0.4-0.6-0.5-0.5-0.6-0.60.60.6-0.50.6-0.5-0.50.5-0.50.50.70.6
Progressive ratio test 1 breakpoint0.20.30.50.6-0.0-0.5-0.5-0.6-0.5-0.5-0.6-0.60.60.6-0.50.6-0.5-0.50.5-0.50.50.70.7
Progressive ratio test 1 inactive lever presses0.30.40.6-0.1-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.6-0.60.7-0.7-0.70.7-0.70.70.70.8
Progressive ratio test 2 active lever presses1.82.12.9-0.3-1.0-1.5-1.4-1.6-1.6-1.5-1.6-1.61.61.6-1.51.6-1.4-1.41.4-1.41.41.71.4
Progressive ratio test 2 breakpoint2.12.43.2-0.5-1.1-1.5-1.4-1.7-1.6-1.6-1.7-1.71.71.7-1.61.7-1.5-1.51.5-1.51.51.81.5
Progressive ratio test 2 inactive lever presses0.30.40.7-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.60.60.6-0.70.6-0.7-0.70.7-0.70.70.60.3
Incentive Sensitization - Responses2.23.23.9-0.8-1.5-1.8-1.7-2.0-1.9-1.8-1.8-1.91.91.8-1.81.9-1.8-1.81.8-1.81.82.01.5
Incentive Sensitization - Breakpoint2.53.24.0-0.9-1.5-1.8-1.7-2.0-1.9-1.8-1.9-1.91.91.9-1.81.9-1.8-1.81.8-1.81.82.01.5
Sum of active levers in priming session hrs 5-60.20.20.40.60.50.40.40.40.40.50.40.4-0.4-0.40.5-0.40.40.4-0.40.4-0.4-0.4-0.6
Progressive ratio0.20.31.0-1.0-0.7-0.4-0.5-0.4-0.5-0.5-0.4-0.40.40.4-0.50.4-0.5-0.50.5-0.50.50.30.4
Food seeking constrained by brief footshock0.40.50.8-0.3-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.80.80.7-0.70.8-0.7-0.70.7-0.70.70.70.9
Seeking ratio, punishment vs. effort0.30.42.61.61.00.50.60.50.60.60.50.5-0.5-0.50.6-0.40.60.6-0.60.6-0.6-0.4-0.3
Retroperitoneal fat weight0.52.24.5-1.7-2.1-1.6-1.6-1.2-1.4-1.6-1.4-1.21.21.4-1.51.3-1.5-1.51.5-1.51.51.31.4
Reaction time number correct2.34.45.1-1.9-2.0-2.1-2.0-2.2-2.1-2.1-2.1-2.22.22.1-2.12.1-2.1-2.12.1-2.12.12.12.3
Reaction time mean minus median0.20.51.0-0.20.20.60.61.00.70.60.81.0-1.0-0.80.6-0.80.60.6-0.60.6-0.6-0.7-0.8
Reaction time mean minus median AUC0.10.31.1-1.0-0.7-0.5-0.5-0.3-0.5-0.5-0.5-0.30.30.4-0.50.4-0.5-0.50.5-0.50.50.50.2
Reaction time num false alarms0.10.10.1-0.2-0.3-0.3-0.3-0.2-0.3-0.3-0.2-0.20.20.3-0.30.3-0.3-0.30.3-0.30.30.20.4
Reaction time num false alarms AUC0.20.40.5-0.4-0.6-0.7-0.6-0.5-0.6-0.6-0.6-0.50.50.6-0.60.6-0.6-0.60.6-0.60.60.60.7
Reaction time trials correct on left2.34.45.1-1.9-2.0-2.1-2.0-2.2-2.1-2.1-2.1-2.22.22.1-2.12.1-2.1-2.12.1-2.12.12.12.3
Reaction time trials on left2.34.25.0-1.8-2.0-2.0-2.0-2.1-2.1-2.0-2.1-2.22.22.1-2.12.0-2.0-2.02.0-2.02.02.12.2
Reaction time mean1.62.63.21.31.41.71.61.71.71.61.71.8-1.8-1.71.6-1.61.51.5-1.51.6-1.6-1.6-1.7
Reaction time mean AUC2.33.64.31.41.72.01.92.02.01.92.02.1-2.1-2.01.9-2.01.81.8-1.81.9-1.9-1.9-2.0
Median of all reaction times1.62.32.71.51.51.61.61.51.51.51.51.6-1.6-1.51.5-1.51.51.5-1.51.5-1.5-1.5-1.5
Reaction time omissions0.30.52.31.50.70.70.70.50.60.70.60.6-0.6-0.60.7-0.60.70.7-0.70.7-0.7-0.5-0.5
Reaction time false alarm rate0.00.10.20.30.20.20.20.40.20.20.30.4-0.4-0.30.3-0.20.20.2-0.20.2-0.2-0.3-0.2
Reaction time premature initiation rate1.11.51.9-0.8-1.1-1.2-1.2-1.3-1.2-1.2-1.2-1.21.21.2-1.21.2-1.2-1.21.2-1.21.21.31.4
Reaction time premature initiations2.34.15.1-1.6-1.9-2.0-2.0-2.1-2.0-2.0-2.1-2.12.12.1-2.12.0-2.0-2.02.0-2.02.02.12.2
Std. dev. reaction times1.22.23.10.91.01.51.41.71.51.41.61.8-1.8-1.61.4-1.61.31.3-1.31.4-1.4-1.5-1.6
Reaction time trials completed2.34.25.0-1.8-2.0-2.0-2.0-2.1-2.1-2.0-2.1-2.22.22.1-2.12.0-2.0-2.02.0-2.02.02.12.2
Reaction time trials AUC2.24.34.9-2.0-2.0-2.0-2.0-2.1-2.1-2.0-2.0-2.22.22.0-2.12.0-2.0-2.02.0-2.02.02.02.2
Run reversals in cocaine runway, females0.10.10.2-0.3-0.2-0.3-0.3-0.4-0.3-0.3-0.4-0.40.40.4-0.30.3-0.3-0.30.3-0.30.30.40.3
Run reversals in cocaine runway, males1.31.42.0-1.4-1.1-1.0-1.1-1.2-1.1-1.1-1.1-1.31.31.1-1.21.1-1.1-1.11.1-1.11.21.11.1
Latency to leave start box in cocaine runway3.74.24.71.31.92.12.12.22.12.12.12.1-2.1-2.12.1-2.12.12.1-2.12.1-2.1-2.2-2.1
Latency to leave start box in cocaine runway, F2.32.73.01.51.61.61.61.71.71.61.71.7-1.7-1.71.6-1.61.61.6-1.61.6-1.6-1.7-1.6
Latency to leave start box in cocaine runway, M2.92.73.01.01.51.61.71.71.71.71.71.6-1.6-1.71.7-1.71.71.7-1.71.7-1.7-1.7-1.7
Std. dev. time between licks in bursts0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Total sessions with >9 infusions0.91.11.9-0.1-0.7-1.1-1.0-1.1-1.1-1.1-1.1-1.11.11.2-1.11.2-1.1-1.11.1-1.01.01.21.4
Short access day 1 total inactive lever presses0.10.10.6-0.8-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.30.30.3-0.30.2-0.3-0.30.3-0.30.30.20.2
Short access day 10 total inactive lever presses0.40.91.10.80.81.01.00.91.01.01.00.9-0.9-1.00.9-1.00.90.9-0.90.9-0.9-1.0-1.0
Short access day 1 total infusions0.60.81.4-0.5-0.8-0.9-0.9-0.9-0.9-0.9-1.0-1.01.01.0-0.90.9-0.9-0.90.9-0.90.91.01.2
Short access day 10 total infusions2.32.93.5-0.9-1.4-1.7-1.7-1.8-1.8-1.7-1.8-1.81.81.8-1.71.8-1.7-1.71.7-1.71.71.91.8
Short access total infusions3.44.36.0-0.7-1.6-2.1-2.0-2.1-2.1-2.1-2.2-2.22.22.2-2.12.2-2.1-2.12.1-2.12.12.32.5
Short access day 1 locomotion0.40.50.7-0.7-0.7-0.7-0.6-0.6-0.7-0.7-0.7-0.70.70.7-0.70.7-0.7-0.70.7-0.70.70.70.8
Short access day 10 total locomotion0.40.71.91.41.00.90.90.80.80.80.80.8-0.8-0.80.8-0.70.80.8-0.80.8-0.8-0.7-0.8
Short access total locomotion0.20.30.50.2-0.2-0.5-0.5-0.5-0.5-0.5-0.5-0.50.50.5-0.50.6-0.5-0.50.5-0.50.50.60.7
One hour access (0.3 mA shock)0.91.12.31.5-0.1-0.9-0.9-1.2-1.0-0.9-1.1-1.11.11.1-0.91.2-0.9-0.90.9-0.90.91.31.2
Compulsive drug intake0.91.11.40.80.81.11.01.01.11.11.11.1-1.1-1.11.1-1.11.11.1-1.11.1-1.1-1.2-1.0
One hour access (shock baseline)1.32.13.20.5-0.7-1.4-1.3-1.6-1.5-1.4-1.6-1.61.61.6-1.41.6-1.4-1.41.4-1.41.41.81.6
Social response proportion0.80.91.6-1.3-1.0-1.1-1.0-0.8-0.9-1.0-0.9-0.80.80.9-0.90.9-0.9-0.90.9-0.90.90.70.9
Social responses1.11.42.2-0.7-0.7-1.3-1.3-1.3-1.2-1.2-1.2-1.21.21.2-1.11.2-1.1-1.11.1-1.11.11.41.5
Social time0.20.21.11.10.1-0.4-0.4-0.5-0.4-0.3-0.4-0.40.40.4-0.30.5-0.3-0.30.3-0.30.30.70.7
Soleus weight0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Bone: stiffness4.87.88.8-3.0-2.8-2.9-2.9-2.8-2.8-2.8-2.8-2.82.82.8-2.82.8-2.7-2.72.7-2.72.72.72.7
Tibialis anterior weight0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Time to tail flick, vehicle, before self-admin0.00.00.50.70.4-0.1-0.0-0.10.00.0-0.00.1-0.10.00.00.10.10.1-0.10.1-0.10.20.0
Time to tail flick, vehicle, after self-admin0.10.10.4-0.7-0.3-0.3-0.2-0.4-0.3-0.3-0.3-0.40.40.3-0.30.2-0.3-0.30.3-0.30.30.30.4
Time to tail flick, test, before self-admin0.20.21.51.20.50.40.30.50.40.40.40.5-0.5-0.40.4-0.30.40.4-0.40.4-0.4-0.3-0.5
Time to tail flick, test, after self-admin0.60.61.00.30.90.80.80.80.80.80.80.8-0.8-0.80.8-0.80.80.8-0.80.8-0.8-0.8-1.0
Delta time to tail flick, vehicle, before/after SA0.00.00.6-0.8-0.20.00.0-0.1-0.0-0.00.0-0.20.2-0.0-0.1-0.1-0.1-0.10.1-0.10.1-0.10.0
Delta time to tail flick, test, before/after SA0.10.11.1-1.10.10.20.30.20.30.30.30.2-0.2-0.30.3-0.40.30.3-0.30.3-0.3-0.4-0.4
Tibia length0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Ambulatory time before self-admin0.30.50.70.0-0.6-0.8-0.8-0.8-0.7-0.7-0.7-0.70.70.7-0.70.8-0.7-0.70.7-0.70.70.80.8
Ambulatory time after self-admin0.20.20.20.50.50.30.40.50.40.40.40.3-0.3-0.40.4-0.40.50.5-0.50.4-0.4-0.4-0.5
Bone: tissue strength5.15.15.4-2.2-2.1-2.3-2.3-2.3-2.3-2.3-2.3-2.32.32.3-2.32.3-2.2-2.22.2-2.22.22.32.3
Total heroin consumption0.60.72.2-1.5-1.1-0.7-0.8-0.7-0.8-0.8-0.7-0.80.80.7-0.80.7-0.8-0.80.8-0.80.80.60.8
Bone: trabecular number4.98.110.0-1.2-2.2-2.9-2.8-3.1-2.9-2.8-3.1-3.13.13.1-2.93.0-2.8-2.82.8-2.82.83.23.2
Bone: trabecular spacing1.72.22.41.01.41.41.41.51.51.51.51.5-1.5-1.51.5-1.51.51.5-1.51.5-1.5-1.5-1.5
Bone: trabecular thickness4.35.35.8-2.0-2.4-2.3-2.3-2.3-2.3-2.3-2.3-2.32.32.3-2.32.3-2.4-2.42.4-2.42.42.32.3
Bone: trabecular tissue density0.00.00.2-0.40.00.00.00.20.20.10.20.2-0.2-0.20.2-0.20.20.2-0.20.2-0.2-0.2-0.2
Water consumed over 24 hours0.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.00.0
Number of responses in last shaping day0.10.11.01.00.70.30.30.20.20.30.20.2-0.2-0.20.3-0.10.30.3-0.30.3-0.3-0.00.0