Hub : Genes

LOC134485266

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC134485266 0.26 0.12 3.9e-03 0.07 0.12 0.07 0.08 7.9e-03 1.2e-03 9.0e-03 5.8e-03
2 NAcc gene expression LOC134485266 0.2 0.08 5.6e-17 0.12 0.12 0.12 0.12 2.3e-18 8.7e-18 5.5e-17 4.2e-18
3 NAcc intron excision ratio chr1_268551133_268612388 0.03 0.02 1.5e-03 0.01 0.02 0.01 0.01 1.0e-02 8.3e-04 3.2e-03 4.7e-03
4 Brain gene expression LOC134485266 0.35 0.11 0.0e+00 0.27 0.28 0.29 0.29 1.3e-25 9.2e-27 4.2e-27 3.4e-27
5 PL gene expression LOC134485266 0.19 0.08 1.1e-15 0.11 0.11 0.11 0.11 1.2e-11 1.8e-12 8.2e-12 1.8e-12
6 BLA gene expression LOC134485266 0.2 0.09 2.3e-08 0.05 0.11 0.11 0.1 8.4e-04 3.1e-06 1.4e-06 3.4e-06
7 IL gene expression LOC134485266 0.22 0.12 6.4e-03 0.02 0.07 0.03 0.04 9.6e-02 8.4e-03 5.2e-02 3.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.91.66.61.5-1.0-2.60.70.7-0.5-0.4
Area under the delay curve1.21.83.61.9-1.00.31.31.4-1.31.7
BMI with tail13.145.679.98.9-7.8-5.27.06.7-6.53.9
BMI without tail5.529.147.56.9-6.5-4.15.85.4-5.13.0
Body weight9.240.375.58.7-7.3-6.36.25.9-5.53.0
Weight adjusted by age1.23.67.42.4-2.7-1.21.81.8-1.61.2
Bone surface0.71.45.01.4-1.2-2.20.70.6-0.7-0.3
Bone volume1.73.36.12.5-2.1-2.11.61.6-1.60.7
Breakpoint value in progressive ratio session0.20.30.90.90.8-0.7-0.20.00.10.3
Number of licking bursts0.51.63.3-0.70.9-1.8-1.1-1.01.3-1.7
Context. condit. distance diff. score0.10.10.3-0.5-0.6-0.3-0.1-0.10.1-0.5
Locomotion velocity, session 10.30.41.0-0.90.40.3-0.5-0.41.0-0.5
Locomotion distance, session 10.20.31.0-0.90.21.0-0.2-0.0-0.0-0.1
Locomotion velocity, session 20.80.92.4-1.51.21.1-0.9-0.70.5-0.6
Locomotion distance, session 20.71.01.70.6-1.30.11.11.3-1.30.6
Locomotion velocity, session 30.30.31.1-1.10.10.7-0.4-0.40.6-0.4
Locomotion distance, session 30.30.41.1-0.6-1.10.90.40.50.00.2
Stereotopy head waving bouts, day 30.30.31.1-0.21.10.9-0.4-0.4-0.20.3
Stereotopy head waving duration, day 30.50.62.4-0.41.50.4-0.9-0.90.2-0.2
Locomotion velocity, session 70.20.20.40.0-0.5-0.70.60.50.1-0.3
Locomotion distance, session 70.40.51.00.3-0.9-0.20.91.0-0.60.2
Stereotopy head waving bouts, day 70.10.10.40.6-0.1-0.20.20.0-0.30.3
Stereotopy head waving duration, day 70.10.10.30.50.5-0.1-0.3-0.40.20.2
Locomotion velocity, session 81.92.33.8-1.90.8-0.5-1.6-1.71.6-1.9
Locomotion distance, session 80.71.02.5-1.6-0.3-0.6-0.7-0.60.7-1.6
Degree of sensitization distance0.30.31.20.60.4-1.10.20.2-0.3-0.1
Degree of sensitization stereotypy0.40.51.31.0-0.7-1.10.40.3-0.00.1
Conditioned locomotion0.00.10.2-0.20.10.4-0.1-0.30.20.1
Cocaine response after cond. corrected1.11.77.2-1.70.92.7-0.5-0.5-0.40.3
Cocaine response after cond. not corrected1.92.76.2-2.41.72.5-1.4-1.30.6-0.3
Cocaine response before conditioning1.72.04.1-1.11.3-0.9-1.6-1.32.0-1.4
Saline control response0.20.30.7-0.2-0.80.80.50.6-0.00.3
Bone: connectivity density0.40.63.30.4-0.4-1.80.00.00.1-0.8
Bone: cortical apparent density1.72.86.9-2.61.62.6-0.9-0.91.3-0.4
Bone: cortical area3.75.911.63.0-3.0-3.42.32.0-1.70.2
Bone: cortical porosity0.10.10.20.40.4-0.5-0.1-0.2-0.10.0
Bone: cortical porosity0.30.41.71.00.0-1.30.20.1-0.2-0.1
Bone: cortical thickness3.35.410.52.4-3.2-2.82.52.3-1.60.2
Bone: cortical thickness4.45.37.62.7-2.6-1.12.72.8-2.41.4
Bone: cortical tissue density2.13.37.7-2.81.82.7-1.1-1.11.5-0.5
Condit. Reinf. active minus inactive responses0.80.91.5-1.20.9-0.5-0.7-0.71.1-1.2
Condit. Reinf. active-inactive response ratio1.51.72.5-1.61.50.0-1.3-1.31.4-1.2
Condit. Reinf. active responses0.60.73.50.2-0.4-1.90.40.40.4-1.0
Condit. Reinf. inactive responses1.41.86.11.3-1.4-2.51.11.1-0.4-0.5
Incentive salience index mean0.20.30.7-0.80.3-0.4-0.00.00.6-0.8
Condit. Reinf. lever presses0.10.20.6-0.1-0.1-0.00.60.8-0.1-0.0
Condit. Reinf. active minus inactive responses0.20.31.70.7-0.0-1.3-0.2-0.20.2-0.3
Condit. Reinf. active-inactive response ratio0.20.41.00.9-0.6-1.00.40.4-0.30.1
Condit. Reinf. active responses0.60.83.51.3-0.6-1.90.20.1-0.1-0.2
Condit. Reinf. inactive responses0.20.31.20.8-0.2-1.10.20.1-0.2-0.0
Condit. Reinf. lever presses0.60.81.71.2-1.2-1.30.70.6-0.60.2
Condit. Reinf. lever reinforcers received0.40.63.00.7-0.3-1.7-0.2-0.30.3-0.5
Conditioned reinforcement - actives0.20.72.7-1.30.81.6-0.2-0.20.30.0
Conditioned reinforcement - inactives0.20.61.0-0.71.00.1-0.9-0.90.9-0.5
Conditioned locomotion0.71.03.0-1.60.91.7-0.5-0.30.6-0.2
Patch foraging indifference point 0 sec1.64.47.32.6-2.7-2.12.12.0-1.80.7
Patch foraging indifference point AUC0.30.61.50.9-1.2-0.90.90.6-0.00.1
Delay disc. indifference point, 0s delay0.70.81.90.9-1.40.21.00.9-0.80.8
Delay disc. indifference point, 16s delay1.01.42.91.7-0.70.31.11.4-1.11.5
Delay disc. indifference point, 2s delay1.01.22.40.8-0.71.50.80.7-1.01.6
Delay disc. indifference point, 24s delay0.71.12.81.7-0.9-0.50.91.1-1.01.0
Delay disc. indifference point, 4s delay1.11.22.11.4-0.80.60.91.0-1.21.4
Delay disc. indifference point, 8s delay0.61.02.11.4-0.40.30.91.1-0.81.3
Indifference point function ln k0.00.10.2-0.10.4-0.0-0.2-0.0-0.3-0.1
Indifference point function log k0.00.10.2-0.10.4-0.0-0.2-0.0-0.3-0.1
Patch foraging total patch changes 0 sec1.75.08.32.9-2.9-2.42.12.0-1.90.7
Patch foraging total patch changes 12 sec2.33.15.12.2-2.3-2.21.81.7-1.10.4
Patch foraging total patch changes 18 sec0.82.03.61.9-1.9-1.81.31.1-0.60.4
Patch foraging total patch changes 24 sec0.20.83.11.2-0.9-1.80.40.30.0-0.2
Patch foraging total patch changes 6 sec2.03.48.22.2-2.3-2.91.61.4-0.8-0.0
Patch foraging time to switch 0 sec0.82.96.8-1.82.61.8-1.9-1.61.0-0.3
Patch foraging water rate 0 sec1.34.79.02.5-3.0-2.12.42.1-1.60.7
Patch foraging water rate 12 sec0.62.35.01.8-2.2-2.21.41.0-0.7-0.0
Patch foraging water rate 18 sec0.92.02.81.5-1.5-0.31.71.7-1.61.0
Patch foraging water rate 24 sec3.44.87.12.6-2.2-0.32.42.4-2.71.8
Patch foraging water rate 6 sec1.52.23.11.8-1.7-0.51.81.6-1.51.1
Seeking ratio, delayed vs. immediate footshock1.82.56.5-2.51.71.2-1.4-1.41.2-1.2
Distance traveled before self-admin0.81.67.8-0.70.12.80.70.8-0.71.2
Distance traveled after self-admin0.71.26.0-0.80.82.50.30.3-0.11.0
Extensor digitorum longus weight1.45.79.73.1-2.9-1.42.72.6-1.71.7
Bone: elastic displacement0.40.61.00.50.11.00.80.8-0.61.0
Bone: elastic work2.73.65.11.8-1.80.72.32.2-2.21.8
Bone: endosteal estimation0.30.82.01.4-0.7-1.10.60.6-1.00.4
Bone: endosteal perimeter0.92.35.32.3-1.5-0.81.31.2-1.81.3
Epididymis fat weight6.633.567.18.2-6.5-7.15.24.7-4.62.2
Delta time in closed arm before/after self-admin0.20.10.4-0.60.40.4-0.5-0.2-0.1-0.2
Delta time in open arm before/after self-admin1.51.72.7-0.61.3-1.3-1.4-1.51.6-1.3
Diff in mean of infusions in LGA sessions0.10.10.50.7-0.1-0.5-0.20.0-0.10.2
Delay discount exponential model param1.52.03.9-2.01.0-0.4-1.3-1.51.4-1.8
Extinction: sum of active levers before priming0.20.31.11.0-0.1-0.10.30.60.00.8
Active lever presses in extinction session 60.50.51.41.2-0.4-0.20.50.6-0.80.8
Bone: final force3.15.07.52.7-2.5-2.62.42.2-2.00.5
Bone: final moment2.74.36.72.6-2.2-2.52.22.0-1.90.5
Food consumed during 24 hour testing period0.10.30.6-0.70.8-0.1-0.6-0.50.1-0.6
Glucose1.72.76.72.6-1.3-1.31.61.5-1.51.2
Heart weight2.94.710.22.8-2.5-3.21.91.7-1.50.2
Delay discount hyperbolic model param1.62.13.9-2.01.0-0.6-1.3-1.41.5-1.9
Intermittent access intake day 1-15 change0.10.41.8-0.00.61.4-0.0-0.2-0.10.8
Intermittent access intake escalation0.10.31.2-0.20.81.1-0.3-0.50.00.5
Intermittent access intake escalation 20.10.20.5-0.30.60.7-0.2-0.40.00.2
Intermitt. access day 1 inactive lever presses0.11.11.8-0.01.3-1.4-1.2-1.01.0-0.8
Intermitt. access day 15 inactive lever presses0.10.30.91.0-0.4-0.80.30.2-0.40.2
Intermitt. access escalation Index0.30.91.5-1.11.20.3-0.9-1.10.8-0.6
Intermittent access day 1 total infusions0.00.10.6-0.30.30.8-0.2-0.20.20.2
Intermittent access day 15 total infusions0.20.62.1-0.41.01.5-0.4-0.50.20.6
Intermittent access terminal intake (last 3 days)0.20.31.10.00.61.1-0.1-0.2-0.00.7
Intermittent access total infusions0.20.20.7-0.30.60.8-0.2-0.30.30.2
Intermittent access day 1 locomotion0.51.03.90.10.12.00.40.7-0.81.3
Intermittent access day 15 total locomotion0.10.30.70.90.30.20.30.2-0.30.8
Intermittent access total locomotion0.70.82.60.3-0.31.60.70.7-0.71.2
Intermittent access standard deviation0.10.30.90.80.50.60.00.1-0.10.9
Left kidney weight2.318.831.15.0-5.6-3.24.84.6-4.12.1
Right kidney weight3.121.631.55.5-5.6-2.65.15.1-4.82.8
Cocaine induced anxiety0.20.62.4-1.50.50.8-0.4-0.40.6-0.7
Post-drug Anxiety0.40.51.4-0.5-0.2-1.2-0.1-0.20.6-1.1
Baseline Anxiety0.40.73.71.1-0.3-1.90.0-0.10.1-0.4
Tail length0.00.10.20.4-0.2-0.50.20.10.40.0
Length with tail0.52.05.91.8-1.6-2.41.11.0-0.4-0.0
Length without tail0.73.512.22.6-1.6-3.51.11.1-0.8-0.1
Times rat made contact with spout0.20.20.40.5-0.2-0.30.40.6-0.60.2
Lifetime Intake0.20.20.5-0.50.60.7-0.3-0.40.4-0.0
Liver weight, left5.810.017.84.2-3.8-2.73.13.0-3.01.7
Liver weight, right3.46.08.42.9-2.8-0.92.72.7-2.71.8
Locomotor activity0.00.10.2-0.3-0.20.5-0.1-0.20.40.1
Locomotor testing distance0.20.42.2-0.8-0.21.50.10.00.30.3
Locomotor testing rearing0.20.82.60.3-0.31.60.70.8-0.61.2
Locomotion in novel chamber0.30.41.2-0.0-0.50.70.50.5-1.10.4
Locomotion in novel chamber post-restriction0.41.21.90.7-1.11.01.21.2-1.41.1
Fecal boli incidents, locomotor time 10.00.10.40.10.1-0.60.0-0.10.6-0.4
Change in fecal boli incidents, locomotor task0.30.30.80.3-0.8-0.90.20.2-0.6-0.3
Time >=10cm from walls, locomotor time 10.20.20.4-0.50.5-0.3-0.3-0.20.5-0.6
Bouts of movement, locomotor time 10.00.00.10.30.10.1-0.3-0.2-0.20.3
Total resting periods, locomotor time 10.00.10.10.2-0.10.2-0.1-0.1-0.30.4
Rest time, locomotor task time 10.30.51.10.2-1.00.00.81.0-0.60.3
Distance moved, locomotor task time 10.00.10.20.40.10.4-0.1-0.2-0.00.5
Vertical activity count, locomotor time 10.00.20.40.5-0.40.40.50.3-0.30.7
Time >=10cm from walls, locomotor time 20.20.52.00.4-0.7-1.40.60.60.0-0.5
Bouts of movement, locomotor time 20.30.93.0-0.81.11.7-0.9-0.6-0.00.4
Total resting periods, locomotor time 20.20.93.5-0.71.01.9-0.8-0.5-0.10.6
Rest time, locomotor task time 20.10.21.1-0.10.01.10.20.3-0.20.6
Distance moved, locomotor task time 20.10.10.60.2-0.5-0.80.2-0.10.0-0.3
Vertical activity count, locomotor time 20.10.20.70.1-0.5-0.80.20.10.1-0.5
Light reinforcement 10.10.30.6-0.1-0.80.60.70.5-0.50.3
Light reinforcement 20.20.31.3-1.1-0.00.7-0.2-0.30.5-0.4
Bone: marrow area0.41.02.31.5-0.9-1.20.70.6-1.10.4
Bone: maximum diameter1.32.55.92.4-1.6-2.41.21.0-1.00.4
Bone: maximum force1.93.86.42.2-2.4-2.52.01.7-1.70.1
Bone: maximum moment1.63.06.32.0-2.0-2.51.71.4-1.5-0.0
Mean time between licks in bursts0.53.25.5-1.62.3-0.7-2.1-2.01.8-1.6
Mean num. licks in bursts1.02.64.11.1-1.11.81.61.7-1.92.0
Cd content in liver0.30.31.2-1.10.10.7-0.3-0.3-0.1-0.5
Co content in liver0.30.30.90.2-0.60.00.70.6-0.90.1
Cu content in liver0.10.10.4-0.30.50.7-0.3-0.3-0.20.1
Fe content in liver1.01.25.40.2-0.1-2.3-0.6-0.60.9-1.3
K content in liver0.30.31.1-0.30.61.0-0.5-0.50.10.4
Mg content in liver0.91.03.80.30.21.90.20.1-0.91.4
Mn content in liver0.50.51.00.8-0.50.50.70.6-0.91.0
Na content in liver0.91.02.51.2-0.11.00.50.7-1.11.6
Rb content in liver0.10.10.20.20.30.5-0.3-0.4-0.10.4
Se content in liver0.60.71.1-0.80.3-0.6-1.0-0.91.0-1.0
Sr content in liver1.10.92.9-1.20.91.7-0.8-0.80.10.1
Zn content in liver1.01.26.0-0.30.02.50.20.3-0.81.3
Bone: minimum diameter2.14.16.62.6-2.6-2.32.01.7-1.60.6
Time in familiar zone, hab. session 13.13.45.71.9-2.40.51.91.9-2.01.8
Time in novel zone, hab. session 13.53.96.3-1.92.3-0.9-2.0-1.92.5-2.0
Total zone transitions, hab. session 11.52.23.71.4-1.90.01.81.8-1.41.1
Total locomotion distance, hab. session 10.60.82.1-0.50.5-1.5-0.7-0.60.8-1.3
Locomotion velocity, hab. session 10.40.61.6-0.50.4-1.3-0.5-0.50.6-1.1
Time in familiar zone, hab. session 20.50.61.5-0.50.3-0.8-0.7-0.81.2-0.8
Time in novel zone, hab. session 20.40.40.90.3-0.40.70.50.7-0.90.7
Total zone transitions, hab. session 20.70.91.50.7-0.90.81.00.9-1.21.1
Total locomotion distance, hab. session 20.20.30.40.6-0.7-0.50.60.6-0.50.2
Locomotion velocity, hab. session 20.30.40.60.7-0.7-0.30.80.8-0.80.4
Novel to familiar place preference ratio1.21.62.7-0.90.4-1.4-1.4-1.41.3-1.6
Novelty place preference1.11.42.1-0.90.4-1.2-1.4-1.31.3-1.5
Time in novel zone, NPP test1.31.62.6-0.70.3-1.6-1.3-1.31.4-1.6
Total zone transitions, NPP test0.50.71.20.7-0.90.21.01.0-1.10.7
Total locomotion distance, NPP test0.10.20.9-0.0-0.3-0.90.10.2-0.1-0.6
Locomotion velocity, NPP test0.10.10.3-0.3-0.1-0.50.00.1-0.3-0.5
Intraocular pressure0.60.93.70.3-0.1-1.9-0.5-0.80.9-1.0
Delta distance traveled before/after self-admin0.10.10.40.40.20.40.20.3-0.00.6
Delta ambulatory time before/after self-admin0.00.10.30.5-0.10.10.20.2-0.10.5
Parametrial fat weight8.520.042.06.5-5.0-5.14.03.7-3.72.0
Pavlov. Cond. lever latency0.91.22.0-0.91.30.0-1.4-1.41.1-0.7
Pavlov. Cond. magazine entry latency0.30.40.60.5-0.80.00.70.6-0.70.5
Pavlov. Cond. change in total contacts1.21.32.21.3-1.2-0.01.51.4-1.01.0
Pavlov. Cond. index score0.91.11.81.0-1.3-0.01.31.2-1.00.8
Pavlov. Cond. latency score0.70.91.50.9-1.20.11.21.1-1.00.8
Pavlov. Cond. lever contacts1.11.31.81.2-1.2-0.01.31.3-1.21.0
Pavlov. Cond. magazine entry number0.50.60.9-0.80.7-0.3-1.0-0.80.9-0.8
Pavlov. Cond. intertrial magazine entries1.01.22.51.0-1.2-1.61.11.2-0.8-0.1
Pavlov. Cond. lever-magazine prob. diff.0.91.11.71.0-1.3-0.11.31.2-1.00.8
Pavlov. Cond. response bias0.60.81.10.9-0.70.31.11.0-1.10.9
Pavlov. Cond. lever latency0.30.41.7-0.30.31.30.50.6-0.40.6
Pavlov. Cond. magazine entry latency0.10.20.5-0.00.2-0.1-0.6-0.70.4-0.1
Pavlov. Cond. change in total contacts0.10.30.60.00.1-0.8-0.6-0.80.6-0.5
Pavlov. Cond. index score0.10.20.70.3-0.3-0.9-0.3-0.50.3-0.3
Pavlov. Cond. latency score0.10.20.70.2-0.2-0.8-0.4-0.60.3-0.3
Pavlov. Cond. lever contacts0.20.31.20.5-0.7-1.1-0.0-0.20.1-0.3
Pavlov. Cond. magazine entry number0.10.10.1-0.40.20.20.30.4-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.71.62.31.5-1.4-0.81.41.5-1.40.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.3-0.3-0.7-0.3-0.40.2-0.2
Pavlov. Cond. response bias0.30.51.50.1-0.2-1.2-0.5-0.80.6-0.7
Time in closed arm before self-admin0.40.60.90.7-0.80.50.90.8-0.60.9
Time in closed arm after self-admin0.70.72.9-0.1-0.41.70.40.4-0.91.0
Time in open arm before self-admin1.41.73.4-1.81.20.2-1.2-1.31.4-1.4
Time in open arm after self-admin2.22.44.4-1.21.6-1.0-1.5-1.62.1-1.6
Bone: periosteal estimation2.04.88.02.8-2.6-2.72.01.8-1.90.6
Bone: periosteal perimeter3.46.713.23.6-2.9-2.02.62.4-2.41.6
Bone: post-yield work0.71.25.7-0.0-0.1-2.4-0.3-0.50.5-1.5
Progressive ratio test 1 active lever presses0.40.72.9-0.50.91.7-0.4-0.4-0.00.7
Progressive ratio test 1 breakpoint0.40.62.8-0.50.91.7-0.4-0.4-0.00.6
Progressive ratio test 1 inactive lever presses0.10.20.4-0.20.5-0.1-0.5-0.40.6-0.2
Progressive ratio test 2 active lever presses0.40.51.10.7-0.30.80.70.7-0.61.0
Progressive ratio test 2 breakpoint0.40.51.00.7-0.30.70.70.6-0.61.0
Progressive ratio test 2 inactive lever presses0.10.40.6-0.30.6-0.8-0.3-0.50.7-0.8
Incentive Sensitization - Responses0.30.91.61.3-0.70.11.10.9-0.81.0
Incentive Sensitization - Breakpoint0.30.71.41.2-0.7-0.01.10.8-0.60.9
Sum of active levers in priming session hrs 5-60.30.21.00.01.00.2-0.5-0.40.50.2
Progressive ratio1.03.04.2-2.02.00.4-2.0-2.01.6-1.5
Food seeking constrained by brief footshock1.11.32.2-1.40.70.6-1.3-1.41.5-0.8
Seeking ratio, punishment vs. effort0.81.72.51.2-1.60.81.51.5-1.01.5
Retroperitoneal fat weight11.450.996.29.8-8.6-8.36.55.9-5.72.7
Reaction time number correct0.10.30.90.60.20.9-0.1-0.0-0.60.9
Reaction time mean minus median0.21.42.61.5-0.80.81.21.2-1.11.6
Reaction time mean minus median AUC0.53.67.51.7-0.82.31.61.6-2.02.7
Reaction time num false alarms0.50.91.60.5-1.3-0.21.31.2-0.90.3
Reaction time num false alarms AUC0.51.22.00.8-1.40.11.41.4-1.30.7
Reaction time trials correct on left0.10.30.90.60.20.9-0.1-0.0-0.60.9
Reaction time trials on left0.10.41.00.60.20.9-0.1-0.0-0.61.0
Reaction time mean0.71.55.20.70.22.30.50.5-0.81.9
Reaction time mean AUC0.81.96.60.70.42.60.60.6-1.02.1
Median of all reaction times1.11.77.00.40.52.70.20.3-0.71.9
Reaction time omissions0.20.31.10.9-0.10.50.30.3-0.21.0
Reaction time false alarm rate0.50.81.70.4-1.3-0.71.11.1-0.7-0.1
Reaction time premature initiation rate0.60.91.80.8-1.30.01.11.3-0.80.6
Reaction time premature initiations0.31.01.51.0-1.00.51.01.2-1.01.1
Std. dev. reaction times0.61.93.71.7-1.10.91.21.2-1.41.9
Reaction time trials completed0.10.41.00.60.20.9-0.1-0.0-0.61.0
Reaction time trials AUC0.10.41.00.70.10.8-0.00.1-0.61.0
Run reversals in cocaine runway, females0.00.00.10.00.2-0.1-0.3-0.00.4-0.1
Run reversals in cocaine runway, males0.30.31.00.0-0.31.00.40.4-0.30.6
Latency to leave start box in cocaine runway0.81.12.5-0.71.41.6-1.1-0.90.80.4
Latency to leave start box in cocaine runway, F0.30.40.7-0.30.60.7-0.9-0.70.60.2
Latency to leave start box in cocaine runway, M0.40.41.7-0.00.71.3-0.10.00.10.8
Std. dev. time between licks in bursts1.63.14.0-1.91.7-0.8-1.8-2.01.8-2.0
Total sessions with >9 infusions0.00.00.2-0.30.10.40.10.10.00.0
Short access day 1 total inactive lever presses0.91.82.7-1.21.0-1.1-1.4-1.51.5-1.7
Short access day 10 total inactive lever presses0.10.61.31.1-1.0-0.70.70.7-0.50.5
Short access day 1 total infusions0.00.10.3-0.10.10.50.00.10.20.2
Short access day 10 total infusions0.61.13.5-1.41.11.9-0.5-0.60.50.1
Short access total infusions0.30.51.1-1.00.71.0-0.4-0.40.5-0.2
Short access day 1 locomotion0.20.41.20.40.41.10.20.4-0.41.0
Short access day 10 total locomotion0.20.82.60.30.11.60.60.7-0.81.3
Short access total locomotion0.60.94.2-0.30.52.00.50.7-0.61.1
One hour access (0.3 mA shock)0.60.71.4-0.51.2-0.0-0.9-1.11.0-0.5
Compulsive drug intake0.20.31.40.4-0.1-1.2-0.3-0.40.2-0.4
One hour access (shock baseline)0.30.81.6-1.01.31.1-0.7-0.60.7-0.2
Social response proportion1.51.93.11.3-1.60.31.71.8-1.21.3
Social responses1.51.93.41.9-1.6-1.51.51.5-1.00.6
Social time0.91.43.21.10.01.50.91.1-1.11.8
Soleus weight5.215.320.44.4-3.51.64.14.1-4.44.5
Bone: stiffness0.91.65.21.2-1.5-2.30.90.7-0.7-0.5
Tibialis anterior weight0.51.83.21.8-1.20.31.41.4-1.01.6
Time to tail flick, vehicle, before self-admin0.30.31.4-0.2-0.2-1.20.0-0.30.0-0.8
Time to tail flick, vehicle, after self-admin0.10.20.60.3-0.8-0.70.2-0.00.2-0.2
Time to tail flick, test, before self-admin1.31.54.30.2-0.42.11.21.1-1.21.4
Time to tail flick, test, after self-admin1.71.83.0-1.21.4-0.7-1.4-1.71.3-1.4
Delta time to tail flick, vehicle, before/after SA0.20.21.01.0-0.4-0.30.20.3-0.00.5
Delta time to tail flick, test, before/after SA1.92.33.3-1.01.1-1.6-1.6-1.81.6-1.8
Tibia length0.30.92.90.9-1.7-0.80.90.9-0.70.2
Ambulatory time before self-admin0.31.04.7-0.70.12.20.60.6-0.50.8
Ambulatory time after self-admin0.60.94.3-0.40.42.10.60.5-0.21.0
Bone: tissue strength0.70.81.1-0.91.1-0.1-1.0-1.01.0-0.7
Total heroin consumption1.72.05.82.4-1.2-1.21.11.3-1.21.1
Bone: trabecular number0.71.36.91.2-0.6-2.60.20.2-0.1-0.7
Bone: trabecular spacing1.62.34.4-2.11.51.4-1.4-1.51.7-0.8
Bone: trabecular thickness3.34.59.63.1-2.1-2.51.91.9-1.80.9
Bone: trabecular tissue density0.81.46.5-1.30.92.5-0.5-0.30.40.6
Water consumed over 24 hours0.10.20.40.20.10.50.40.6-0.60.5
Number of responses in last shaping day0.10.10.30.00.10.6-0.00.1-0.10.4