Hub : Genes

LOC134485266

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC134485266 0.26 0.12 3.9e-03 0.07 0.12 0.07 0.08 7.9e-03 1.2e-03 9.0e-03 5.8e-03
2 NAcc gene expression LOC134485266 0.2 0.08 5.6e-17 0.12 0.12 0.12 0.12 2.3e-18 8.7e-18 5.5e-17 4.3e-18
3 NAcc intron excision ratio chr1_268551133_268612388 0.03 0.02 1.5e-03 0.01 0.02 0.01 0.01 1.0e-02 8.3e-04 3.2e-03 4.8e-03
4 Brain gene expression LOC134485266 0.35 0.11 0.0e+00 0.27 0.28 0.29 0.29 1.3e-25 9.2e-27 4.2e-27 3.6e-27
5 BLA gene expression LOC134485266 0.2 0.09 2.3e-08 0.05 0.11 0.11 0.1 8.4e-04 3.1e-06 1.3e-06 3.4e-06
6 PL gene expression LOC134485266 0.19 0.08 1.1e-15 0.11 0.11 0.11 0.11 1.2e-11 1.8e-12 8.2e-12 1.9e-12
7 IL gene expression LOC134485266 0.22 0.12 6.4e-03 0.02 0.07 0.03 0.04 9.6e-02 8.4e-03 5.2e-02 3.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.91.56.61.51.0-2.60.70.5-0.1-0.4
Area under the delay curve1.72.03.61.91.00.31.31.31.81.7
BMI with tail12.442.779.98.97.8-5.27.06.54.93.9
BMI without tail8.927.247.56.96.5-4.15.85.13.93.0
Body weight8.637.675.58.77.3-6.36.25.54.03.0
Weight adjusted by age2.23.47.42.42.7-1.21.81.61.41.2
Bone surface0.71.35.01.41.2-2.20.70.70.1-0.3
Bone volume1.73.16.12.52.1-2.11.61.61.00.7
Breakpoint value in progressive ratio session0.20.30.90.9-0.8-0.7-0.2-0.10.10.3
Number of licking bursts1.01.63.3-0.7-0.9-1.8-1.1-1.3-1.1-1.7
Context. condit. distance diff. score0.10.10.3-0.50.6-0.3-0.1-0.1-0.4-0.5
Locomotion velocity, session 10.40.41.0-0.9-0.40.3-0.5-1.0-0.5-0.5
Locomotion distance, session 10.20.31.0-0.9-0.21.0-0.20.00.1-0.1
Locomotion velocity, session 20.80.92.4-1.5-1.21.1-0.9-0.5-0.5-0.6
Locomotion distance, session 20.60.91.60.61.30.11.11.31.00.6
Locomotion velocity, session 30.30.31.1-1.1-0.10.7-0.4-0.6-0.3-0.4
Locomotion distance, session 30.30.41.1-0.61.10.90.4-0.00.40.2
Stereotopy head waving bouts, day 30.30.31.1-0.2-1.10.9-0.40.20.20.3
Stereotopy head waving duration, day 30.40.52.4-0.4-1.50.4-0.9-0.2-0.2-0.2
Locomotion velocity, session 70.20.20.40.00.5-0.70.6-0.1-0.0-0.3
Locomotion distance, session 70.30.30.90.30.9-0.20.90.60.30.2
Stereotopy head waving bouts, day 70.20.20.70.60.1-0.20.20.30.80.3
Stereotopy head waving duration, day 70.10.10.30.5-0.5-0.1-0.3-0.20.50.2
Locomotion velocity, session 81.92.33.8-1.9-0.8-0.5-1.6-1.6-1.7-1.9
Locomotion distance, session 80.81.12.5-1.60.3-0.6-0.7-0.7-1.1-1.6
Degree of sensitization distance0.30.31.20.6-0.4-1.10.20.3-0.3-0.1
Degree of sensitization stereotypy0.50.51.31.00.7-1.10.50.00.80.1
Conditioned locomotion0.00.00.2-0.2-0.10.4-0.1-0.20.00.1
Cocaine response after cond. corrected1.41.77.2-1.7-0.92.7-0.50.4-0.30.3
Cocaine response after cond. not corrected2.32.76.2-2.4-1.72.5-1.4-0.6-1.1-0.3
Cocaine response before conditioning1.82.14.1-1.1-1.3-0.9-1.6-2.0-1.5-1.4
Saline control response0.20.30.7-0.20.80.80.50.00.50.3
Bone: connectivity density0.40.73.30.40.4-1.80.0-0.1-0.6-0.8
Bone: cortical apparent density2.02.76.9-2.6-1.62.6-0.9-1.3-0.7-0.4
Bone: cortical area3.75.611.63.03.0-3.42.31.71.20.2
Bone: cortical porosity0.10.10.20.4-0.4-0.5-0.10.1-0.10.0
Bone: cortical porosity0.40.41.71.0-0.0-1.30.20.20.0-0.1
Bone: cortical thickness3.05.010.52.43.2-2.82.51.61.40.2
Bone: cortical thickness4.25.07.32.72.6-1.12.72.42.31.4
Bone: cortical tissue density2.43.27.7-2.8-1.82.7-1.1-1.5-0.8-0.5
Condit. Reinf. active minus inactive responses0.91.11.5-1.2-0.9-0.5-0.7-1.1-1.2-1.2
Condit. Reinf. active-inactive response ratio1.61.72.5-1.6-1.50.0-1.3-1.4-1.5-1.2
Condit. Reinf. active responses0.60.73.50.20.4-1.90.4-0.4-0.5-1.0
Condit. Reinf. inactive responses1.31.66.11.31.4-2.51.10.40.4-0.5
Incentive salience index mean0.30.40.7-0.8-0.3-0.4-0.0-0.6-0.8-0.8
Condit. Reinf. lever presses0.00.10.4-0.10.1-0.00.60.1-0.1-0.0
Condit. Reinf. active minus inactive responses0.30.31.70.70.0-1.3-0.2-0.2-0.2-0.3
Condit. Reinf. active-inactive response ratio0.30.41.00.90.6-1.00.40.30.30.1
Condit. Reinf. active responses0.60.83.51.30.6-1.90.20.10.0-0.2
Condit. Reinf. inactive responses0.20.31.20.80.2-1.10.20.2-0.0-0.0
Condit. Reinf. lever presses0.60.81.71.21.2-1.30.70.60.40.2
Condit. Reinf. lever reinforcers received0.40.63.00.70.3-1.7-0.2-0.3-0.4-0.5
Conditioned reinforcement - actives0.40.72.7-1.3-0.81.6-0.2-0.30.00.0
Conditioned reinforcement - inactives0.40.51.0-0.7-1.00.1-0.9-0.9-0.6-0.5
Conditioned locomotion0.81.03.0-1.6-0.91.7-0.5-0.6-0.1-0.2
Patch foraging indifference point 0 sec2.34.27.32.62.7-2.12.11.81.70.7
Patch foraging indifference point AUC0.40.61.50.91.2-0.90.90.00.60.1
Delay disc. indifference point, 0s delay0.80.91.90.91.40.21.00.81.00.8
Delay disc. indifference point, 16s delay1.41.52.91.70.70.31.11.11.61.5
Delay disc. indifference point, 2s delay1.21.32.40.80.71.50.81.01.31.6
Delay disc. indifference point, 24s delay1.11.22.81.70.9-0.50.91.01.31.0
Delay disc. indifference point, 4s delay1.21.32.11.40.80.60.91.21.41.4
Delay disc. indifference point, 8s delay0.91.12.11.40.40.30.90.81.41.3
Indifference point function ln k0.00.10.2-0.1-0.4-0.0-0.20.3-0.2-0.1
Indifference point function log k0.00.10.2-0.1-0.4-0.0-0.20.3-0.2-0.1
Patch foraging total patch changes 0 sec2.64.98.32.92.9-2.42.21.91.70.7
Patch foraging total patch changes 12 sec2.33.05.12.22.3-2.21.81.11.20.4
Patch foraging total patch changes 18 sec1.21.93.61.91.9-1.81.30.60.90.4
Patch foraging total patch changes 24 sec0.50.83.11.20.9-1.80.4-0.00.4-0.2
Patch foraging total patch changes 6 sec2.13.38.22.22.3-2.91.60.81.1-0.0
Patch foraging time to switch 0 sec1.32.76.8-1.8-2.61.8-1.9-1.0-1.1-0.3
Patch foraging water rate 0 sec2.14.59.02.53.0-2.12.41.61.70.7
Patch foraging water rate 12 sec1.12.35.01.82.2-2.21.40.70.8-0.0
Patch foraging water rate 18 sec1.21.92.81.51.5-0.31.71.61.41.0
Patch foraging water rate 24 sec3.44.77.12.62.2-0.32.42.72.31.8
Patch foraging water rate 6 sec1.52.13.11.81.7-0.51.81.51.41.1
Seeking ratio, delayed vs. immediate footshock2.12.66.5-2.5-1.71.2-1.4-1.2-1.6-1.2
Distance traveled before self-admin1.31.77.8-0.7-0.12.80.70.71.01.2
Distance traveled after self-admin1.01.26.0-0.8-0.82.50.30.10.51.0
Extensor digitorum longus weight1.35.19.73.12.9-1.42.71.71.61.7
Bone: elastic displacement0.50.61.10.5-0.11.00.80.61.01.0
Bone: elastic work2.83.65.21.81.80.72.32.22.31.8
Bone: endosteal estimation0.40.82.01.40.7-1.10.61.00.40.4
Bone: endosteal perimeter1.12.45.32.31.5-0.81.31.81.41.3
Epididymis fat weight9.231.667.18.26.5-7.15.24.63.02.2
Delta time in closed arm before/after self-admin0.20.20.4-0.6-0.40.4-0.50.1-0.4-0.2
Delta time in open arm before/after self-admin1.81.82.7-0.6-1.3-1.3-1.4-1.6-1.6-1.3
Diff in mean of infusions in LGA sessions0.10.10.50.70.1-0.5-0.20.10.30.2
Delay discount exponential model param2.02.23.9-2.0-1.0-0.4-1.3-1.4-1.9-1.8
Extinction: sum of active levers before priming0.30.31.11.00.1-0.10.3-0.00.40.8
Active lever presses in extinction session 60.50.51.41.20.4-0.20.50.80.70.8
Bone: final force3.04.77.52.72.5-2.62.42.01.50.5
Bone: final moment2.54.16.72.62.2-2.52.21.91.40.5
Food consumed during 24 hour testing period0.20.30.6-0.7-0.8-0.1-0.6-0.1-0.7-0.6
Glucose1.72.76.72.61.3-1.31.61.51.61.2
Heart weight2.84.410.22.82.5-3.21.91.51.00.2
Delay discount hyperbolic model param2.12.33.9-2.0-1.0-0.6-1.3-1.5-1.9-1.9
Intermittent access intake day 1-15 change0.20.41.8-0.0-0.61.4-0.00.10.40.8
Intermittent access intake escalation0.20.31.2-0.2-0.81.1-0.3-0.00.10.5
Intermittent access intake escalation 20.10.10.5-0.3-0.60.7-0.2-0.0-0.10.2
Intermitt. access day 1 inactive lever presses0.31.11.8-0.0-1.3-1.4-1.2-1.0-1.2-0.8
Intermitt. access day 15 inactive lever presses0.20.30.91.00.4-0.80.30.40.50.2
Intermitt. access escalation Index0.60.81.5-1.1-1.20.3-1.0-0.8-1.1-0.6
Intermittent access day 1 total infusions0.10.10.6-0.3-0.30.8-0.2-0.2-0.00.2
Intermittent access day 15 total infusions0.40.62.1-0.4-1.01.5-0.4-0.20.20.6
Intermittent access terminal intake (last 3 days)0.20.31.10.0-0.61.1-0.10.00.40.7
Intermittent access total infusions0.20.20.7-0.3-0.60.8-0.2-0.30.10.2
Intermittent access day 1 locomotion0.81.13.90.1-0.12.00.40.81.01.3
Intermittent access day 15 total locomotion0.20.30.70.9-0.30.20.30.30.80.8
Intermittent access total locomotion0.80.92.60.30.31.60.70.71.01.2
Intermittent access standard deviation0.20.40.90.8-0.50.60.00.10.80.9
Left kidney weight3.717.231.15.05.6-3.24.84.13.12.1
Right kidney weight4.319.731.55.55.6-2.65.14.83.52.8
Cocaine induced anxiety0.40.62.4-1.5-0.50.8-0.4-0.6-0.4-0.7
Post-drug Anxiety0.50.51.4-0.50.2-1.2-0.1-0.6-0.6-1.1
Baseline Anxiety0.60.73.71.10.3-1.90.0-0.1-0.3-0.4
Tail length0.00.10.20.40.2-0.50.2-0.4-0.10.0
Length with tail0.41.95.91.81.6-2.41.10.40.3-0.0
Length without tail1.03.412.22.61.6-3.51.10.80.5-0.1
Times rat made contact with spout0.10.20.40.50.2-0.30.40.60.20.2
Lifetime Intake0.20.20.5-0.5-0.60.7-0.3-0.4-0.1-0.0
Liver weight, left5.79.517.84.23.8-2.73.13.02.31.7
Liver weight, right3.15.58.42.92.8-0.92.72.71.81.8
Locomotor activity0.00.10.2-0.30.20.5-0.1-0.4-0.10.1
Locomotor testing distance0.20.42.2-0.80.21.50.1-0.3-0.00.3
Locomotor testing rearing0.40.82.60.30.31.60.70.60.81.2
Locomotion in novel chamber0.30.41.2-0.00.50.70.51.10.50.4
Locomotion in novel chamber post-restriction0.81.42.60.71.11.01.21.41.61.1
Fecal boli incidents, locomotor time 10.10.10.40.1-0.1-0.60.0-0.60.1-0.4
Change in fecal boli incidents, locomotor task0.30.30.80.30.8-0.90.20.6-0.1-0.3
Time >=10cm from walls, locomotor time 10.20.20.4-0.5-0.5-0.3-0.3-0.5-0.5-0.6
Bouts of movement, locomotor time 10.10.10.20.3-0.10.1-0.30.2-0.40.3
Total resting periods, locomotor time 10.10.10.10.20.10.2-0.10.3-0.30.4
Rest time, locomotor task time 10.30.30.90.21.00.00.80.60.40.3
Distance moved, locomotor task time 10.10.10.20.4-0.10.4-0.10.00.50.5
Vertical activity count, locomotor time 10.10.30.50.50.40.40.50.30.70.7
Time >=10cm from walls, locomotor time 20.30.52.00.40.7-1.40.6-0.00.2-0.5
Bouts of movement, locomotor time 20.60.93.0-0.8-1.11.7-1.00.0-0.40.4
Total resting periods, locomotor time 20.50.93.5-0.7-1.01.9-0.80.1-0.30.6
Rest time, locomotor task time 20.20.21.1-0.1-0.01.10.20.20.20.6
Distance moved, locomotor task time 20.10.10.60.20.5-0.80.2-0.00.2-0.3
Vertical activity count, locomotor time 20.10.20.70.10.5-0.80.2-0.1-0.0-0.5
Light reinforcement 10.10.30.6-0.10.80.60.70.50.30.3
Light reinforcement 20.20.41.3-1.10.00.7-0.2-0.5-0.5-0.4
Bone: marrow area0.40.92.31.50.9-1.20.71.10.50.4
Bone: maximum diameter1.32.55.92.41.6-2.41.21.00.70.4
Bone: maximum force2.03.56.42.22.4-2.52.01.71.10.1
Bone: maximum moment1.62.86.32.02.0-2.51.71.50.8-0.0
Mean time between licks in bursts1.33.35.5-1.6-2.3-0.7-2.1-1.8-2.2-1.6
Mean num. licks in bursts1.62.54.11.11.11.81.61.91.42.0
Cd content in liver0.30.31.2-1.1-0.10.7-0.30.10.0-0.5
Co content in liver0.30.30.90.20.60.00.70.90.60.1
Cu content in liver0.10.10.4-0.3-0.50.7-0.30.20.30.1
Fe content in liver1.11.35.40.20.1-2.3-0.6-0.9-1.0-1.3
K content in liver0.30.31.1-0.3-0.61.0-0.5-0.10.10.4
Mg content in liver1.11.13.80.3-0.21.90.20.90.91.4
Mn content in liver0.50.61.00.80.50.50.70.90.71.0
Na content in liver1.11.12.51.20.11.00.51.11.21.6
Rb content in liver0.10.10.20.2-0.30.5-0.30.10.20.4
Se content in liver0.60.71.1-0.8-0.3-0.6-1.0-1.0-0.8-1.0
Sr content in liver1.00.92.9-1.2-0.91.7-0.8-0.1-0.30.1
Zn content in liver1.21.36.0-0.3-0.02.50.20.80.91.3
Bone: minimum diameter2.13.96.62.62.6-2.32.01.61.30.6
Time in familiar zone, hab. session 13.53.45.71.92.40.51.92.01.81.8
Time in novel zone, hab. session 14.04.06.3-1.9-2.3-0.9-2.0-2.5-2.0-2.0
Total zone transitions, hab. session 11.52.03.71.41.90.01.81.41.51.1
Total locomotion distance, hab. session 10.60.82.1-0.5-0.5-1.5-0.7-0.8-0.8-1.3
Locomotion velocity, hab. session 10.40.61.6-0.5-0.4-1.3-0.5-0.6-0.7-1.1
Time in familiar zone, hab. session 20.70.71.7-0.5-0.3-0.8-0.7-1.2-1.3-0.8
Time in novel zone, hab. session 20.50.51.00.30.40.70.50.91.00.7
Total zone transitions, hab. session 20.70.91.50.70.90.81.01.20.91.1
Total locomotion distance, hab. session 20.20.30.40.60.7-0.50.60.50.30.2
Locomotion velocity, hab. session 20.30.40.60.70.7-0.30.80.80.50.4
Novel to familiar place preference ratio1.41.62.7-0.9-0.4-1.4-1.4-1.3-1.3-1.6
Novelty place preference1.21.32.1-0.9-0.4-1.2-1.4-1.3-1.2-1.5
Time in novel zone, NPP test1.51.62.6-0.7-0.3-1.6-1.3-1.4-1.3-1.6
Total zone transitions, NPP test0.40.61.20.70.90.21.01.10.50.7
Total locomotion distance, NPP test0.10.20.9-0.00.3-0.90.10.1-0.2-0.6
Locomotion velocity, NPP test0.10.10.3-0.30.1-0.50.00.3-0.2-0.5
Intraocular pressure0.60.93.70.30.1-1.9-0.5-0.9-0.6-1.0
Delta distance traveled before/after self-admin0.10.10.40.4-0.20.40.20.00.40.6
Delta ambulatory time before/after self-admin0.10.10.30.50.10.10.20.10.20.5
Parametrial fat weight8.018.942.06.55.0-5.14.03.72.32.0
Pavlov. Cond. lever latency0.81.02.0-0.9-1.30.0-1.4-1.1-0.9-0.7
Pavlov. Cond. magazine entry latency0.20.30.60.50.80.00.70.70.30.5
Pavlov. Cond. change in total contacts1.11.22.21.31.2-0.01.51.00.91.0
Pavlov. Cond. index score0.81.01.81.01.3-0.01.31.00.70.8
Pavlov. Cond. latency score0.60.81.50.91.20.11.21.00.60.8
Pavlov. Cond. lever contacts1.01.21.81.21.2-0.01.31.21.11.0
Pavlov. Cond. magazine entry number0.40.60.9-0.8-0.7-0.3-1.0-0.9-0.5-0.8
Pavlov. Cond. intertrial magazine entries0.81.02.51.01.2-1.61.10.80.6-0.1
Pavlov. Cond. lever-magazine prob. diff.0.80.91.71.01.3-0.11.31.00.70.8
Pavlov. Cond. response bias0.60.71.10.90.70.31.11.10.80.9
Pavlov. Cond. lever latency0.30.41.7-0.3-0.31.30.50.40.50.6
Pavlov. Cond. magazine entry latency0.10.10.4-0.0-0.2-0.1-0.6-0.4-0.7-0.1
Pavlov. Cond. change in total contacts0.20.30.60.0-0.1-0.8-0.6-0.6-0.6-0.5
Pavlov. Cond. index score0.20.20.70.30.3-0.9-0.3-0.3-0.5-0.3
Pavlov. Cond. latency score0.20.20.70.20.2-0.8-0.4-0.3-0.6-0.3
Pavlov. Cond. lever contacts0.20.31.20.50.7-1.1-0.0-0.1-0.1-0.3
Pavlov. Cond. magazine entry number0.00.10.1-0.4-0.20.20.30.10.2-0.1
Pavlov. Cond. intertrial magazine entries1.01.52.31.51.4-0.81.41.41.10.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.30.3-0.7-0.3-0.2-0.4-0.2
Pavlov. Cond. response bias0.30.51.50.10.2-1.2-0.5-0.6-0.7-0.7
Time in closed arm before self-admin0.50.60.90.70.80.50.90.60.70.9
Time in closed arm after self-admin0.70.72.9-0.10.41.70.40.90.41.0
Time in open arm before self-admin1.51.63.4-1.8-1.20.2-1.2-1.4-1.0-1.4
Time in open arm after self-admin2.12.44.4-1.2-1.6-1.0-1.5-2.1-1.5-1.6
Bone: periosteal estimation2.24.58.02.82.6-2.72.01.91.20.6
Bone: periosteal perimeter3.86.513.23.62.9-2.02.62.42.11.6
Bone: post-yield work0.91.35.7-0.00.1-2.4-0.3-0.5-1.0-1.5
Progressive ratio test 1 active lever presses0.50.72.9-0.5-0.91.7-0.40.00.20.7
Progressive ratio test 1 breakpoint0.50.62.8-0.5-0.91.7-0.40.00.20.6
Progressive ratio test 1 inactive lever presses0.10.10.4-0.2-0.5-0.1-0.5-0.6-0.3-0.2
Progressive ratio test 2 active lever presses0.50.61.10.70.30.80.70.61.01.0
Progressive ratio test 2 breakpoint0.50.51.00.70.30.70.70.60.91.0
Progressive ratio test 2 inactive lever presses0.20.40.6-0.3-0.6-0.8-0.3-0.7-0.5-0.8
Incentive Sensitization - Responses0.60.91.61.30.70.11.10.81.01.0
Incentive Sensitization - Breakpoint0.60.71.41.20.7-0.01.10.61.00.9
Sum of active levers in priming session hrs 5-60.30.31.00.0-1.00.2-0.5-0.5-0.40.2
Progressive ratio1.72.64.2-2.0-2.00.4-2.0-1.6-1.2-1.5
Food seeking constrained by brief footshock0.91.12.2-1.4-0.70.6-1.3-1.5-0.6-0.8
Seeking ratio, punishment vs. effort1.11.62.51.21.60.81.51.01.21.5
Retroperitoneal fat weight11.248.096.29.88.6-8.36.55.73.72.7
Reaction time number correct0.20.40.90.6-0.20.9-0.10.60.40.9
Reaction time mean minus median0.61.52.61.50.80.81.21.11.41.6
Reaction time mean minus median AUC1.53.97.51.70.82.31.62.02.12.7
Reaction time num false alarms0.50.71.60.51.3-0.21.30.90.50.3
Reaction time num false alarms AUC0.71.02.00.81.40.11.41.30.80.7
Reaction time trials correct on left0.20.40.90.6-0.20.9-0.10.60.40.9
Reaction time trials on left0.20.41.00.6-0.20.9-0.10.60.41.0
Reaction time mean1.11.75.20.7-0.22.30.50.81.31.9
Reaction time mean AUC1.42.26.60.7-0.42.60.61.01.42.1
Median of all reaction times1.31.87.00.4-0.52.70.20.71.21.9
Reaction time omissions0.20.31.10.90.10.50.30.20.21.0
Reaction time false alarm rate0.40.61.70.41.3-0.71.10.70.4-0.1
Reaction time premature initiation rate0.60.81.60.81.30.01.10.81.00.6
Reaction time premature initiations0.61.01.31.01.00.51.01.01.11.1
Std. dev. reaction times1.12.03.71.71.10.91.21.41.51.9
Reaction time trials completed0.20.41.00.6-0.20.9-0.10.60.41.0
Reaction time trials AUC0.20.41.00.7-0.10.8-0.00.60.41.0
Run reversals in cocaine runway, females0.00.00.10.0-0.2-0.1-0.3-0.4-0.0-0.1
Run reversals in cocaine runway, males0.30.31.00.00.31.00.40.30.60.6
Latency to leave start box in cocaine runway0.91.02.5-0.7-1.41.6-1.1-0.8-0.20.4
Latency to leave start box in cocaine runway, F0.30.30.8-0.3-0.60.7-0.9-0.6-0.30.2
Latency to leave start box in cocaine runway, M0.50.41.7-0.0-0.71.3-0.1-0.10.60.8
Std. dev. time between licks in bursts2.33.14.0-1.9-1.7-0.8-1.8-1.8-2.0-2.0
Total sessions with >9 infusions0.00.10.2-0.3-0.10.40.1-0.00.30.0
Short access day 1 total inactive lever presses1.41.82.7-1.2-1.0-1.1-1.4-1.5-1.5-1.7
Short access day 10 total inactive lever presses0.20.61.31.11.0-0.70.70.50.40.5
Short access day 1 total infusions0.00.10.3-0.1-0.10.50.0-0.20.10.2
Short access day 10 total infusions0.81.03.5-1.4-1.11.9-0.5-0.5-0.30.1
Short access total infusions0.40.41.1-1.0-0.71.0-0.4-0.5-0.3-0.2
Short access day 1 locomotion0.40.41.20.4-0.41.10.20.40.71.0
Short access day 10 total locomotion0.50.92.60.3-0.11.60.60.80.91.3
Short access total locomotion0.81.04.2-0.3-0.52.00.50.61.01.1
One hour access (0.3 mA shock)0.50.61.4-0.5-1.2-0.0-0.9-1.0-0.7-0.5
Compulsive drug intake0.30.31.40.40.1-1.2-0.3-0.2-0.6-0.4
One hour access (shock baseline)0.50.71.6-1.0-1.31.1-0.7-0.7-0.3-0.2
Social response proportion1.51.72.91.31.60.31.71.21.21.3
Social responses1.41.83.41.91.6-1.51.51.01.00.6
Social time1.11.53.21.1-0.01.50.91.11.31.8
Soleus weight5.114.920.44.43.51.64.14.43.84.5
Bone: stiffness0.91.55.21.21.5-2.30.90.70.2-0.5
Tibialis anterior weight0.51.73.21.81.20.31.41.01.11.6
Time to tail flick, vehicle, before self-admin0.30.31.4-0.20.2-1.20.0-0.0-0.3-0.8
Time to tail flick, vehicle, after self-admin0.10.20.60.30.8-0.70.2-0.20.1-0.2
Time to tail flick, test, before self-admin1.61.64.30.20.42.11.21.21.41.4
Time to tail flick, test, after self-admin1.71.83.0-1.2-1.4-0.7-1.4-1.3-1.7-1.4
Delta time to tail flick, vehicle, before/after SA0.30.31.01.00.4-0.30.20.00.50.5
Delta time to tail flick, test, before/after SA2.42.54.5-1.0-1.1-1.6-1.6-1.6-2.1-1.8
Tibia length0.30.92.90.91.7-0.80.90.70.70.2
Ambulatory time before self-admin0.71.04.7-0.7-0.12.20.60.50.70.8
Ambulatory time after self-admin0.80.94.3-0.4-0.42.10.60.20.71.0
Bone: tissue strength0.70.71.1-0.9-1.1-0.1-1.0-1.0-0.7-0.7
Total heroin consumption1.72.05.82.41.2-1.21.11.21.31.1
Bone: trabecular number0.81.36.91.20.6-2.60.20.1-0.4-0.7
Bone: trabecular spacing1.72.34.4-2.1-1.51.4-1.4-1.7-1.4-0.8
Bone: trabecular thickness3.54.39.63.12.1-2.51.91.81.60.9
Bone: trabecular tissue density1.01.46.5-1.3-0.92.5-0.5-0.4-0.30.6
Water consumed over 24 hours0.10.20.30.2-0.10.50.40.60.40.5
Number of responses in last shaping day0.10.10.30.0-0.10.6-0.00.10.50.4