Hub : Genes

LOC134485174

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC134485174 0.04 0.03 5.4e-03 0.02 0.02 0.01 0.02 9.7e-03 1.4e-02 2.1e-02 1.7e-02
2 IC gene expression LOC134485174 0.09 0.06 8.4e-03 0.05 0.04 0.03 0.05 4.9e-03 6.7e-03 1.7e-02 3.9e-03
3 BLA gene expression LOC134485174 0.13 0.09 4.8e-05 0.08 0.06 0.03 0.07 7.1e-05 3.4e-04 8.3e-03 1.2e-04
4 PL gene expression LOC134485174 0.05 0.03 3.0e-05 0.03 0.04 0.04 0.03 1.2e-04 6.0e-05 9.1e-05 1.7e-04
5 NAcc gene expression LOC134485174 0.08 0.04 3.1e-07 0.05 0.04 0.04 0.05 1.1e-07 3.7e-07 2.0e-07 9.3e-08
6 Brain gene expression LOC134485174 0.08 0.05 2.2e-04 0.02 0.02 0.04 0.02 1.0e-02 6.2e-03 2.7e-04 2.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density1.12.02.8-1.61.6-1.71.50.71.1
Area under the delay curve0.10.10.30.4-0.30.4-0.4-0.5-0.1
BMI with tail3.713.016.9-4.14.0-3.73.93.2-2.4
BMI without tail3.217.024.2-4.94.8-4.44.83.2-1.3
Body weight2.310.314.8-3.83.8-3.63.62.5-0.5
Weight adjusted by age0.10.20.6-0.20.2-0.30.40.8-0.1
Bone surface1.12.12.7-1.61.6-1.61.51.5-0.5
Bone volume1.63.24.6-2.12.1-2.11.91.5-0.1
Breakpoint value in progressive ratio session1.01.82.41.5-1.51.5-1.3-1.21.0
Number of licking bursts1.75.17.32.5-2.52.7-2.7-1.5-1.3
Context. condit. distance diff. score0.30.40.70.8-0.70.6-0.6-0.60.2
Locomotion velocity, session 10.00.00.1-0.00.1-0.30.20.0-0.0
Locomotion distance, session 11.21.53.5-1.11.1-1.11.20.51.9
Locomotion velocity, session 20.10.10.20.2-0.2-0.0-0.1-0.30.4
Locomotion distance, session 22.02.73.6-1.81.8-1.91.91.31.0
Locomotion velocity, session 30.50.50.8-0.70.7-0.90.80.60.7
Locomotion distance, session 30.30.31.4-0.40.4-0.30.41.2-0.2
Stereotopy head waving bouts, day 30.70.81.20.8-0.91.0-0.9-1.10.7
Stereotopy head waving duration, day 30.30.30.70.4-0.40.6-0.5-0.90.5
Locomotion velocity, session 72.22.44.1-1.21.2-1.31.32.0-2.0
Locomotion distance, session 71.01.36.80.1-0.00.1-0.20.9-2.6
Stereotopy head waving bouts, day 70.10.20.3-0.50.3-0.30.5-0.00.5
Stereotopy head waving duration, day 71.51.93.1-1.61.5-1.41.81.10.4
Locomotion velocity, session 80.20.31.5-0.20.1-0.20.2-0.01.2
Locomotion distance, session 80.20.30.6-0.40.5-0.80.70.40.2
Degree of sensitization distance0.40.41.40.3-0.30.5-0.7-1.2-0.4
Degree of sensitization stereotypy1.51.62.7-1.51.4-1.41.71.1-0.0
Conditioned locomotion0.50.61.01.0-1.00.5-0.60.4-0.9
Cocaine response after cond. corrected0.10.20.30.5-0.50.3-0.4-0.4-0.1
Cocaine response after cond. not corrected0.10.20.5-0.30.3-0.30.30.4-0.7
Cocaine response before conditioning2.42.93.7-1.81.8-1.51.71.9-1.7
Saline control response0.20.30.70.6-0.50.5-0.4-0.80.2
Bone: connectivity density0.71.01.4-1.11.1-1.21.21.0-0.1
Bone: cortical apparent density0.91.52.01.3-1.21.4-1.3-1.01.1
Bone: cortical area3.15.07.4-2.72.7-2.52.41.7-0.4
Bone: cortical porosity0.60.71.0-0.90.8-0.91.00.80.1
Bone: cortical porosity0.20.30.8-0.40.3-0.50.50.40.9
Bone: cortical thickness1.11.93.2-1.81.8-1.61.40.5-0.5
Bone: cortical thickness0.60.71.5-1.00.9-0.80.6-0.3-1.2
Bone: cortical tissue density1.01.52.01.3-1.21.4-1.3-1.01.1
Condit. Reinf. active minus inactive responses0.20.30.40.5-0.50.4-0.4-0.50.7
Condit. Reinf. active-inactive response ratio0.20.21.10.3-0.30.1-0.10.01.0
Condit. Reinf. active responses0.20.20.40.4-0.40.4-0.3-0.60.4
Condit. Reinf. inactive responses0.10.10.2-0.10.10.2-0.0-0.4-0.4
Incentive salience index mean0.00.10.20.1-0.1-0.00.10.5-0.3
Condit. Reinf. lever presses0.10.20.70.2-0.10.00.10.8-0.7
Condit. Reinf. active minus inactive responses0.91.45.8-0.80.7-0.60.9-0.12.4
Condit. Reinf. active-inactive response ratio0.71.15.9-0.10.10.20.1-0.72.4
Condit. Reinf. active responses0.91.34.7-0.90.8-0.80.90.42.2
Condit. Reinf. inactive responses1.01.42.5-1.21.1-1.41.21.6-0.1
Condit. Reinf. lever presses1.42.02.8-1.71.6-1.41.60.91.2
Condit. Reinf. lever reinforcers received0.81.15.6-0.50.4-0.50.60.12.4
Conditioned reinforcement - actives0.00.10.1-0.10.2-0.20.3-0.30.2
Conditioned reinforcement - inactives0.20.61.01.0-0.80.5-0.6-1.00.6
Conditioned locomotion0.00.10.10.4-0.30.2-0.1-0.30.1
Patch foraging indifference point 0 sec0.20.50.9-0.50.5-0.90.7-0.70.7
Patch foraging indifference point AUC0.20.61.2-1.11.0-0.70.80.2-0.3
Delay disc. indifference point, 0s delay1.21.31.9-1.11.4-1.01.01.1-1.4
Delay disc. indifference point, 16s delay3.65.15.92.3-2.32.3-2.4-2.41.8
Delay disc. indifference point, 2s delay4.55.06.5-2.42.5-2.22.32.0-2.0
Delay disc. indifference point, 24s delay2.43.85.32.3-2.32.0-2.0-1.61.3
Delay disc. indifference point, 4s delay0.10.10.5-0.30.4-0.30.1-0.2-0.7
Delay disc. indifference point, 8s delay0.10.10.5-0.10.1-0.20.20.1-0.7
Indifference point function ln k0.10.31.0-0.30.4-1.00.70.20.0
Indifference point function log k0.10.31.0-0.30.4-1.00.70.20.0
Patch foraging total patch changes 0 sec0.20.71.1-0.60.5-1.10.9-0.81.0
Patch foraging total patch changes 12 sec0.40.52.1-0.40.3-0.50.50.11.4
Patch foraging total patch changes 18 sec0.10.31.6-0.1-0.00.0-0.1-0.7-1.3
Patch foraging total patch changes 24 sec0.10.50.9-1.00.8-0.80.7-0.20.4
Patch foraging total patch changes 6 sec1.22.16.50.3-0.40.2-0.4-2.42.6
Patch foraging time to switch 0 sec0.72.84.52.1-2.12.0-2.0-0.0-0.0
Patch foraging water rate 0 sec0.20.61.0-0.80.8-0.90.80.3-1.0
Patch foraging water rate 12 sec0.31.22.0-1.31.4-1.41.1-0.1-0.2
Patch foraging water rate 18 sec0.20.41.1-0.70.8-1.00.6-0.30.1
Patch foraging water rate 24 sec0.50.71.2-1.01.1-0.90.60.1-1.0
Patch foraging water rate 6 sec0.10.21.0-0.20.3-0.20.1-1.0-0.3
Seeking ratio, delayed vs. immediate footshock0.10.20.6-0.40.4-0.30.00.0-0.8
Distance traveled before self-admin0.40.83.4-0.60.6-0.70.30.2-1.8
Distance traveled after self-admin1.83.16.1-1.71.6-1.71.21.6-2.5
Extensor digitorum longus weight4.919.423.0-4.84.7-4.54.44.8-3.0
Bone: elastic displacement0.50.61.80.6-0.80.6-0.6-1.30.1
Bone: elastic work0.40.60.9-0.90.8-0.90.80.30.5
Bone: endosteal estimation1.63.85.4-2.02.0-2.22.12.30.5
Bone: endosteal perimeter1.12.64.8-1.51.5-1.61.52.2-1.1
Epididymis fat weight0.62.84.2-2.02.1-1.92.00.90.2
Delta time in closed arm before/after self-admin0.50.51.5-0.50.3-0.00.31.2-0.9
Delta time in open arm before/after self-admin1.31.62.5-1.31.3-1.41.60.6-1.1
Diff in mean of infusions in LGA sessions0.20.42.10.3-0.30.3-0.1-1.40.6
Delay discount exponential model param0.10.20.3-0.50.4-0.50.50.50.1
Extinction: sum of active levers before priming0.30.51.00.9-1.00.8-0.7-0.40.2
Active lever presses in extinction session 60.10.10.4-0.1-0.1-0.40.3-0.2-0.6
Bone: final force5.18.311.4-3.43.3-3.43.22.30.7
Bone: final moment4.57.310.3-3.23.1-3.23.11.90.9
Food consumed during 24 hour testing period1.22.43.5-1.81.8-1.81.91.30.4
Glucose0.10.20.60.2-0.20.1-0.1-0.50.8
Heart weight0.10.10.2-0.40.4-0.50.50.00.2
Delay discount hyperbolic model param0.00.00.1-0.10.1-0.10.10.20.3
Intermittent access intake day 1-15 change0.10.40.80.9-0.80.5-0.8-0.2-0.3
Intermittent access intake escalation0.10.51.01.0-0.90.6-0.9-0.4-0.2
Intermittent access intake escalation 20.30.61.21.0-0.90.5-1.1-0.30.3
Intermitt. access day 1 inactive lever presses0.00.40.70.6-0.60.9-0.7-0.5-0.2
Intermitt. access day 15 inactive lever presses0.10.51.2-0.50.6-0.81.10.7-0.5
Intermitt. access escalation Index0.10.30.8-0.60.5-0.70.90.3-0.2
Intermittent access day 1 total infusions0.20.71.1-0.91.0-0.81.10.5-0.4
Intermittent access day 15 total infusions0.00.00.20.1-0.0-0.00.1-0.0-0.4
Intermittent access terminal intake (last 3 days)0.10.10.3-0.30.4-0.50.50.2-0.3
Intermittent access total infusions1.01.21.9-1.11.2-1.11.40.7-0.9
Intermittent access day 1 locomotion0.10.30.5-0.50.6-0.50.7-0.0-0.4
Intermittent access day 15 total locomotion0.10.21.00.3-0.20.20.1-1.00.2
Intermittent access total locomotion0.20.30.8-0.50.6-0.40.9-0.3-0.1
Intermittent access standard deviation0.41.92.2-1.31.3-1.51.31.4-1.4
Left kidney weight1.310.616.9-3.73.7-4.13.62.5-0.9
Right kidney weight1.712.117.6-4.04.1-4.23.82.3-1.6
Cocaine induced anxiety0.10.30.90.4-0.40.7-0.3-0.1-1.0
Post-drug Anxiety0.50.61.40.7-0.70.7-0.7-1.20.3
Baseline Anxiety0.30.51.6-0.30.4-0.80.2-0.61.3
Tail length0.42.03.1-1.81.8-1.61.60.50.5
Length with tail0.10.31.0-0.50.5-0.60.2-0.21.0
Length without tail0.21.32.51.3-1.20.9-1.6-1.10.6
Times rat made contact with spout2.42.73.9-1.51.5-1.51.61.8-2.0
Lifetime Intake1.41.72.7-1.31.4-1.41.60.9-1.0
Liver weight, left0.81.45.80.8-0.70.7-0.9-0.32.4
Liver weight, right0.20.30.60.6-0.60.7-0.80.4-0.1
Locomotor activity0.10.21.3-0.0-0.00.1-0.00.11.2
Locomotor testing distance0.10.31.0-0.40.4-0.20.40.21.0
Locomotor testing rearing0.10.52.60.3-0.30.5-0.4-0.21.6
Locomotion in novel chamber0.20.30.5-0.70.6-0.70.6-0.1-0.1
Locomotion in novel chamber post-restriction0.30.91.80.8-0.70.6-0.9-1.31.3
Fecal boli incidents, locomotor time 10.10.40.80.7-0.70.9-0.60.30.2
Change in fecal boli incidents, locomotor task0.70.71.1-0.80.8-1.10.6-0.81.1
Time >=10cm from walls, locomotor time 10.80.91.5-1.00.8-1.21.20.9-0.6
Bouts of movement, locomotor time 12.73.55.32.1-2.31.9-1.9-1.51.4
Total resting periods, locomotor time 13.54.15.72.3-2.42.2-2.1-1.41.5
Rest time, locomotor task time 10.81.32.11.4-1.41.4-1.40.10.4
Distance moved, locomotor task time 10.51.32.7-1.31.2-1.61.4-0.1-0.1
Vertical activity count, locomotor time 10.42.53.8-1.91.8-1.72.00.3-1.1
Time >=10cm from walls, locomotor time 20.92.43.2-1.61.5-1.81.81.5-1.1
Bouts of movement, locomotor time 20.20.52.3-0.10.3-0.60.61.5-0.0
Total resting periods, locomotor time 20.20.72.5-0.30.6-0.80.71.6-0.1
Rest time, locomotor task time 20.00.00.0-0.10.1-0.10.0-0.10.2
Distance moved, locomotor task time 20.40.61.1-0.70.6-0.90.70.4-1.1
Vertical activity count, locomotor time 20.10.30.5-0.70.5-0.60.6-0.3-0.6
Light reinforcement 10.10.30.70.4-0.50.2-0.4-0.60.8
Light reinforcement 20.10.20.70.1-0.1-0.10.1-0.50.8
Bone: marrow area1.43.44.8-1.91.9-2.01.92.20.5
Bone: maximum diameter2.34.66.3-2.52.5-2.42.32.00.3
Bone: maximum force3.87.510.5-3.23.2-3.23.02.20.9
Bone: maximum moment3.46.48.9-3.02.9-3.02.81.81.0
Mean time between licks in bursts0.00.30.60.5-0.50.6-0.4-0.10.8
Mean num. licks in bursts2.97.811.4-3.13.1-3.33.42.30.0
Cd content in liver2.22.56.71.0-1.01.0-0.8-2.12.6
Co content in liver0.30.31.6-0.20.1-0.10.0-1.3-0.5
Cu content in liver0.81.01.3-1.11.1-1.11.10.0-0.9
Fe content in liver0.30.41.60.4-0.40.3-0.3-1.3-0.7
K content in liver0.40.31.0-0.50.4-0.50.60.2-1.0
Mg content in liver0.20.31.1-0.10.1-0.20.40.5-1.1
Mn content in liver0.50.61.1-0.60.6-0.60.80.8-1.0
Na content in liver5.56.28.5-2.32.3-2.42.42.9-2.7
Rb content in liver2.93.410.51.3-1.41.4-1.2-3.21.6
Se content in liver0.20.30.4-0.50.4-0.50.50.6-0.5
Sr content in liver0.80.70.9-0.90.9-0.80.91.0-0.4
Zn content in liver1.61.92.4-1.51.4-1.51.51.5-0.3
Bone: minimum diameter2.14.15.1-2.32.2-2.22.22.2-0.2
Time in familiar zone, hab. session 10.60.62.40.5-0.50.7-0.6-1.5-0.4
Time in novel zone, hab. session 10.70.82.8-0.60.5-0.70.71.70.4
Total zone transitions, hab. session 12.53.65.5-2.22.2-2.32.30.8-0.1
Total locomotion distance, hab. session 15.27.410.8-3.33.2-3.33.21.30.4
Locomotion velocity, hab. session 14.25.98.5-2.92.9-2.92.91.01.1
Time in familiar zone, hab. session 20.30.40.6-0.80.7-0.70.60.3-0.4
Time in novel zone, hab. session 20.30.31.40.3-0.30.2-0.1-0.31.2
Total zone transitions, hab. session 22.33.04.2-2.02.0-2.12.10.71.1
Total locomotion distance, hab. session 23.14.15.9-2.42.4-2.42.30.91.0
Locomotion velocity, hab. session 23.74.97.1-2.62.6-2.72.61.21.0
Novel to familiar place preference ratio0.60.81.10.9-0.91.0-0.9-1.10.3
Novelty place preference0.60.81.10.9-0.90.9-1.0-1.0-0.1
Time in novel zone, NPP test0.60.71.30.8-0.90.9-0.9-1.20.3
Total zone transitions, NPP test1.52.33.6-1.71.8-1.71.90.90.6
Total locomotion distance, NPP test1.82.53.6-1.91.9-1.81.70.71.0
Locomotion velocity, NPP test1.42.03.0-1.71.7-1.61.60.70.3
Intraocular pressure0.10.10.5-0.30.4-0.10.30.70.2
Delta distance traveled before/after self-admin0.60.61.1-0.70.6-0.80.91.0-0.7
Delta ambulatory time before/after self-admin0.61.01.7-0.90.9-1.11.11.3-0.5
Parametrial fat weight2.55.911.0-2.52.6-3.33.10.31.3
Pavlov. Cond. lever latency0.81.14.20.1-0.20.1-0.5-2.11.4
Pavlov. Cond. magazine entry latency3.34.28.8-1.61.6-1.41.83.0-2.5
Pavlov. Cond. change in total contacts2.12.36.7-0.50.6-0.00.52.6-2.5
Pavlov. Cond. index score1.62.06.5-0.60.7-0.40.92.5-1.8
Pavlov. Cond. latency score1.41.75.4-0.60.7-0.51.02.3-1.7
Pavlov. Cond. lever contacts1.82.26.8-0.80.9-0.71.12.6-1.8
Pavlov. Cond. magazine entry number1.92.46.60.8-0.90.6-1.0-2.62.3
Pavlov. Cond. intertrial magazine entries2.12.56.50.8-0.91.0-1.2-2.22.6
Pavlov. Cond. lever-magazine prob. diff.1.92.37.4-0.90.9-0.61.22.7-1.8
Pavlov. Cond. response bias2.43.08.6-0.80.9-0.61.02.9-2.6
Pavlov. Cond. lever latency1.01.42.11.4-1.41.4-1.4-0.7-0.5
Pavlov. Cond. magazine entry latency0.60.91.41.1-1.11.2-1.1-0.0-0.6
Pavlov. Cond. change in total contacts0.61.57.8-0.10.2-0.10.2-1.22.8
Pavlov. Cond. index score0.00.10.3-0.10.20.00.1-0.00.6
Pavlov. Cond. latency score0.00.00.1-0.20.2-0.00.20.20.2
Pavlov. Cond. lever contacts0.91.31.9-1.31.4-1.31.40.70.4
Pavlov. Cond. magazine entry number1.62.13.0-1.61.6-1.71.61.1-0.8
Pavlov. Cond. intertrial magazine entries1.53.44.6-2.02.0-2.12.11.70.5
Pavlov. Cond. lever-magazine prob. diff.0.00.10.30.1-0.00.2-0.1-0.00.5
Pavlov. Cond. response bias0.10.10.3-0.40.4-0.30.40.10.5
Time in closed arm before self-admin0.10.10.3-0.20.3-0.50.50.3-0.3
Time in closed arm after self-admin0.20.30.50.3-0.30.5-0.7-0.70.5
Time in open arm before self-admin1.11.42.31.2-1.21.3-1.5-0.80.6
Time in open arm after self-admin2.22.53.7-1.41.4-1.41.61.7-1.9
Bone: periosteal estimation3.27.69.8-3.13.1-3.13.02.8-0.2
Bone: periosteal perimeter1.83.54.4-2.12.0-2.02.12.0-0.4
Bone: post-yield work2.23.85.0-2.02.1-2.22.21.31.8
Progressive ratio test 1 active lever presses0.30.40.6-0.60.6-0.50.80.6-0.8
Progressive ratio test 1 breakpoint0.20.40.5-0.50.6-0.40.70.6-0.7
Progressive ratio test 1 inactive lever presses0.00.10.2-0.00.20.20.50.3-0.5
Progressive ratio test 2 active lever presses0.00.00.10.10.00.20.10.1-0.0
Progressive ratio test 2 breakpoint0.00.00.10.2-0.00.30.00.00.0
Progressive ratio test 2 inactive lever presses0.10.20.5-0.40.6-0.30.70.4-0.4
Incentive Sensitization - Responses0.00.10.10.3-0.20.40.10.20.1
Incentive Sensitization - Breakpoint0.00.00.10.2-0.10.30.10.20.1
Sum of active levers in priming session hrs 5-61.11.01.51.2-1.20.9-0.8-0.71.0
Progressive ratio0.10.30.9-0.00.2-0.00.0-0.81.0
Food seeking constrained by brief footshock0.91.21.61.0-1.01.2-1.3-1.30.5
Seeking ratio, punishment vs. effort0.20.51.8-0.10.0-0.20.21.0-1.3
Retroperitoneal fat weight1.04.65.7-2.32.3-2.32.3-0.22.4
Reaction time number correct0.30.91.51.0-1.01.0-1.2-0.60.8
Reaction time mean minus median0.00.20.6-0.40.3-0.70.6-0.1-0.4
Reaction time mean minus median AUC0.00.30.90.2-0.2-0.30.2-0.90.8
Reaction time num false alarms0.40.71.31.0-1.01.0-1.1-0.5-0.1
Reaction time num false alarms AUC0.20.50.80.9-0.90.8-0.9-0.2-0.1
Reaction time trials correct on left0.30.91.51.0-1.01.0-1.2-0.60.8
Reaction time trials on left0.30.91.51.1-1.01.0-1.2-0.60.8
Reaction time mean0.10.20.4-0.40.5-0.60.60.0-0.4
Reaction time mean AUC0.00.10.2-0.10.1-0.40.30.0-0.3
Median of all reaction times0.10.20.3-0.40.5-0.50.60.2-0.4
Reaction time omissions0.10.10.30.6-0.50.2-0.2-0.00.3
Reaction time false alarm rate0.10.20.70.3-0.30.3-0.20.2-0.8
Reaction time premature initiation rate1.21.82.9-1.31.3-1.41.11.7-1.2
Reaction time premature initiations0.20.51.6-0.50.5-0.70.31.3-0.6
Std. dev. reaction times0.10.30.6-0.50.5-0.70.7-0.20.1
Reaction time trials completed0.30.91.51.1-1.01.0-1.2-0.60.8
Reaction time trials AUC0.20.61.10.8-0.80.8-1.0-0.50.7
Run reversals in cocaine runway, females4.85.46.3-2.52.5-2.32.22.1-2.4
Run reversals in cocaine runway, males0.40.40.70.8-0.80.7-0.7-0.50.3
Latency to leave start box in cocaine runway0.30.41.30.2-0.00.30.1-1.11.1
Latency to leave start box in cocaine runway, F0.10.20.40.4-0.20.5-0.3-0.40.6
Latency to leave start box in cocaine runway, M0.60.51.9-0.20.1-0.10.4-1.41.1
Std. dev. time between licks in bursts0.10.10.4-0.20.2-0.20.40.60.5
Total sessions with >9 infusions4.96.18.2-2.72.8-2.72.92.0-1.5
Short access day 1 total inactive lever presses0.20.51.0-0.50.7-0.81.00.6-0.1
Short access day 10 total inactive lever presses0.21.42.01.4-1.41.3-1.2-0.70.8
Short access day 1 total infusions0.71.42.1-1.21.4-1.31.31.2-0.2
Short access day 10 total infusions1.93.24.7-1.81.9-1.92.21.6-1.3
Short access total infusions2.94.16.0-2.22.3-2.22.41.6-1.2
Short access day 1 locomotion0.30.50.8-0.50.7-0.90.80.5-0.8
Short access day 10 total locomotion1.14.35.8-2.22.2-1.82.41.9-1.8
Short access total locomotion2.53.86.0-2.22.3-2.22.41.0-0.9
One hour access (0.3 mA shock)0.00.00.2-0.10.2-0.10.5-0.1-0.1
Compulsive drug intake0.10.10.4-0.0-0.10.6-0.2-0.30.6
One hour access (shock baseline)0.00.00.20.3-0.2-0.00.0-0.4-0.0
Social response proportion0.40.52.00.3-0.3-0.10.1-0.81.4
Social responses0.50.71.10.9-1.00.7-0.6-0.71.1
Social time1.01.52.21.2-1.21.1-1.0-1.31.5
Soleus weight2.47.110.6-3.23.2-3.23.01.5-0.4
Bone: stiffness2.85.17.0-2.62.6-2.62.41.70.9
Tibialis anterior weight6.823.231.7-5.65.5-5.45.24.0-2.3
Time to tail flick, vehicle, before self-admin0.10.10.4-0.60.6-0.10.40.10.0
Time to tail flick, vehicle, after self-admin1.63.34.42.1-2.11.9-1.7-1.11.9
Time to tail flick, test, before self-admin0.10.10.3-0.10.30.20.40.6-0.1
Time to tail flick, test, after self-admin0.40.41.10.5-0.70.1-0.11.0-0.9
Delta time to tail flick, vehicle, before/after SA0.40.40.70.8-0.90.4-0.5-0.50.7
Delta time to tail flick, test, before/after SA0.30.30.9-0.20.1-0.60.40.6-0.9
Tibia length0.10.31.0-0.20.2-0.40.2-0.81.0
Ambulatory time before self-admin0.10.52.4-0.30.3-0.3-0.1-0.3-1.5
Ambulatory time after self-admin1.82.96.5-1.61.6-1.51.11.5-2.6
Bone: tissue strength0.30.31.4-0.30.3-0.40.30.41.2
Total heroin consumption0.40.50.70.8-0.80.8-0.6-0.60.7
Bone: trabecular number0.81.42.1-1.31.3-1.41.30.71.1
Bone: trabecular spacing0.81.11.71.3-1.31.2-1.1-0.1-1.0
Bone: trabecular thickness2.12.94.3-2.12.0-1.91.7-0.51.4
Bone: trabecular tissue density0.10.20.9-0.10.1-0.0-0.1-0.30.9
Water consumed over 24 hours0.71.36.20.6-0.60.6-0.50.8-2.5
Number of responses in last shaping day0.10.20.4-0.30.4-0.20.10.70.4