Hub : Genes

LOC134485155

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC134485155 0.19 0.11 8.8e-03 0.01 0 -0.01 0 2.0e-01 3.3e-01 9.8e-01 2.6e-01
2 Brain gene expression LOC134485155 0.05 0.03 3.8e-05 0.03 0.05 0.04 0.03 2.1e-03 2.8e-05 2.2e-04 3.9e-04
3 NAcc gene expression LOC134485155 0.15 0.06 0.0e+00 0.15 0.21 0.2 0.21 1.6e-22 8.3e-31 8.9e-30 4.5e-31
4 BLA gene expression LOC134485155 0.09 0.05 9.7e-05 0.02 0.05 0.04 0.03 1.9e-02 1.2e-03 4.2e-03 8.8e-03
5 NAcc intron excision ratio chr1_160748088_160760694 0.13 0.07 7.7e-09 0.06 0.05 0.05 0.04 9.3e-09 2.5e-08 1.8e-08 2.0e-07
6 IC gene expression LOC134485155 0.2 0.1 1.2e-06 0.02 0.1 0.08 0.07 3.8e-02 5.5e-05 3.1e-04 6.2e-04
7 PL gene expression LOC134485155 0.13 0.07 6.3e-12 0.11 0.12 0.12 0.12 7.1e-12 8.0e-13 1.7e-12 1.8e-13
8 NAcc intron excision ratio chr1_160748088_160748462 0.12 0.07 3.0e-07 0.02 0.05 0.05 0.04 1.1e-04 9.4e-08 1.1e-07 1.9e-06
9 Adipose gene expression LOC134485155 0.09 0.04 2.0e-08 0.07 0.06 0.06 0.06 3.9e-08 1.0e-07 5.0e-07 2.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.10.6-0.70.1-0.20.2-0.40.10.4-0.00.5
Area under the delay curve0.50.81.50.9-1.2-1.2-1.10.7-1.0-0.80.70.3
BMI with tail1.24.111.4-0.42.43.22.1-0.22.00.60.6-3.4
BMI without tail0.94.615.1-0.42.53.32.20.01.90.30.7-3.9
Body weight2.08.620.9-1.43.44.53.10.22.91.61.4-4.6
Weight adjusted by age0.10.20.6-0.40.30.6-0.0-0.8-0.3-0.7-0.50.1
Bone surface0.91.93.01.7-1.5-1.5-1.60.9-1.7-1.7-0.20.4
Bone volume0.40.81.51.0-0.9-0.8-1.00.7-1.1-1.20.2-0.1
Breakpoint value in progressive ratio session0.20.31.1-0.70.2-0.10.4-0.50.41.1-0.00.8
Number of licking bursts1.03.15.0-1.72.02.12.1-1.12.22.10.1-1.0
Context. condit. distance diff. score3.23.96.12.3-2.4-2.4-2.50.9-2.4-1.8-0.71.2
Locomotion velocity, session 11.01.12.60.5-1.2-1.6-1.10.4-1.1-0.6-0.41.5
Locomotion distance, session 10.60.71.21.1-1.0-1.0-1.10.3-0.9-0.9-0.60.6
Locomotion velocity, session 20.70.81.51.0-1.0-1.0-1.00.7-1.1-1.2-0.20.1
Locomotion distance, session 20.20.31.10.30.00.20.10.80.40.20.7-1.0
Locomotion velocity, session 30.40.40.90.1-0.7-0.8-0.70.4-1.0-0.9-0.20.6
Locomotion distance, session 32.02.34.30.7-1.8-2.0-1.90.7-2.1-1.5-0.51.5
Stereotopy head waving bouts, day 33.13.75.8-2.02.32.12.3-2.42.11.7-1.2-0.6
Stereotopy head waving duration, day 30.50.61.6-0.80.60.50.80.11.10.81.3-0.6
Locomotion velocity, session 70.20.20.60.3-0.6-0.7-0.70.0-0.5-0.10.10.6
Locomotion distance, session 70.50.61.21.0-1.0-0.8-1.10.5-0.9-0.70.10.2
Stereotopy head waving bouts, day 70.30.41.0-0.1-0.5-0.9-0.5-0.6-0.5-0.4-0.71.0
Stereotopy head waving duration, day 70.20.30.60.3-0.6-0.7-0.60.1-0.6-0.80.10.5
Locomotion velocity, session 85.97.112.12.5-3.4-3.5-3.22.7-2.9-2.01.31.4
Locomotion distance, session 81.42.13.51.8-1.9-1.8-1.81.2-1.6-1.20.10.3
Degree of sensitization distance0.70.82.20.40.91.30.7-0.21.00.30.3-1.5
Degree of sensitization stereotypy2.02.23.81.0-1.7-1.9-1.80.0-1.9-1.6-0.91.6
Conditioned locomotion0.30.31.5-0.1-0.1-0.30.20.50.60.71.2-0.4
Cocaine response after cond. corrected0.10.20.40.6-0.1-0.0-0.3-0.2-0.4-0.4-0.70.3
Cocaine response after cond. not corrected0.30.51.60.9-0.3-0.3-0.5-0.5-0.6-0.4-1.30.8
Cocaine response before conditioning0.60.72.6-0.30.0-0.30.0-1.2-0.10.3-1.41.6
Saline control response1.01.34.10.9-0.20.1-0.11.80.3-0.12.0-1.9
Bone: connectivity density0.61.02.70.1-0.8-1.3-0.8-0.7-1.1-0.4-1.21.6
Bone: cortical apparent density0.40.61.2-0.70.50.60.70.21.11.00.7-0.9
Bone: cortical area0.20.30.80.9-0.20.3-0.40.6-0.3-0.70.4-0.7
Bone: cortical porosity0.30.30.8-0.70.1-0.10.0-0.8-0.10.2-0.90.9
Bone: cortical porosity0.50.51.9-0.70.2-0.20.1-1.1-0.20.1-1.41.0
Bone: cortical thickness0.10.20.3-0.10.50.60.4-0.40.50.4-0.2-0.2
Bone: cortical thickness0.91.12.61.6-0.8-0.7-1.10.1-1.0-1.5-0.80.7
Bone: cortical tissue density0.30.51.0-0.70.50.50.70.11.01.00.6-0.8
Condit. Reinf. active minus inactive responses0.30.40.8-0.50.60.90.40.50.1-0.60.7-0.9
Condit. Reinf. active-inactive response ratio0.50.51.1-0.80.71.00.60.40.4-0.30.9-0.9
Condit. Reinf. active responses0.30.30.8-0.50.70.90.60.20.4-0.10.6-0.7
Condit. Reinf. inactive responses0.00.00.10.30.00.10.0-0.1-0.00.1-0.10.1
Incentive salience index mean0.10.20.9-0.20.10.2-0.20.4-0.5-0.90.4-0.2
Condit. Reinf. lever presses0.50.71.60.3-0.9-1.0-1.00.4-1.3-1.10.30.9
Condit. Reinf. active minus inactive responses2.33.57.22.7-1.7-1.0-1.92.3-1.6-2.11.9-1.0
Condit. Reinf. active-inactive response ratio1.11.82.81.7-1.4-1.0-1.51.6-1.2-1.51.4-0.3
Condit. Reinf. active responses3.34.710.03.2-1.7-0.8-2.02.9-1.6-2.42.2-1.8
Condit. Reinf. inactive responses0.81.13.61.4-0.20.3-0.31.5-0.3-1.00.9-1.9
Condit. Reinf. lever presses8.412.224.04.5-3.6-2.6-3.54.9-2.8-3.23.6-1.4
Condit. Reinf. lever reinforcers received3.95.411.83.4-2.0-1.1-2.33.0-1.9-2.72.1-1.6
Conditioned reinforcement - actives0.41.72.61.2-1.5-1.6-1.5-0.2-1.6-1.0-1.40.9
Conditioned reinforcement - inactives0.20.41.1-0.60.1-0.30.3-1.00.21.0-1.10.5
Conditioned locomotion2.23.35.80.9-2.0-2.4-1.9-0.7-2.2-1.1-2.12.0
Patch foraging indifference point 0 sec0.61.84.91.7-1.1-0.7-1.12.2-0.8-1.01.7-1.0
Patch foraging indifference point AUC0.10.30.90.4-0.4-0.2-0.50.4-0.7-1.0-0.2-0.1
Delay disc. indifference point, 0s delay0.91.12.41.2-0.8-0.7-1.0-0.3-1.2-1.5-1.60.2
Delay disc. indifference point, 16s delay0.71.03.10.9-1.0-1.0-0.71.4-0.2-0.11.8-0.6
Delay disc. indifference point, 2s delay0.60.71.40.8-1.0-1.0-1.00.1-1.2-0.9-0.40.6
Delay disc. indifference point, 24s delay0.40.64.0-0.2-0.1-0.10.20.80.50.62.0-0.2
Delay disc. indifference point, 4s delay1.21.22.51.2-1.2-0.8-1.30.9-1.5-1.60.4-0.2
Delay disc. indifference point, 8s delay0.60.91.70.9-1.2-1.3-1.10.9-0.9-0.91.00.1
Indifference point function ln k0.10.41.20.4-0.7-0.7-0.41.1-0.00.31.1-0.1
Indifference point function log k0.10.41.20.4-0.7-0.7-0.41.1-0.00.31.1-0.1
Patch foraging total patch changes 0 sec0.71.94.91.8-1.3-0.8-1.22.2-0.9-1.11.7-0.9
Patch foraging total patch changes 12 sec0.30.40.90.9-0.4-0.1-0.60.0-0.7-1.0-0.7-0.3
Patch foraging total patch changes 18 sec0.61.43.71.4-1.0-0.7-1.21.3-1.3-1.90.4-0.6
Patch foraging total patch changes 24 sec0.10.51.50.8-0.4-0.2-0.70.3-0.9-1.2-0.7-0.3
Patch foraging total patch changes 6 sec0.30.42.10.2-0.20.0-0.01.20.10.11.5-0.5
Patch foraging time to switch 0 sec1.03.97.3-2.42.01.62.0-2.71.82.1-1.80.9
Patch foraging water rate 0 sec0.72.83.81.9-1.9-1.6-1.91.9-1.8-1.91.0-0.0
Patch foraging water rate 12 sec0.52.04.41.2-1.5-1.3-1.32.1-0.9-1.02.1-0.6
Patch foraging water rate 18 sec0.61.22.71.3-0.8-0.4-0.71.5-0.4-0.71.7-1.5
Patch foraging water rate 24 sec0.91.32.70.9-1.5-1.5-1.11.7-0.7-0.31.4-0.4
Patch foraging water rate 6 sec0.60.91.50.8-1.1-1.2-1.01.2-0.7-0.41.10.3
Seeking ratio, delayed vs. immediate footshock0.71.03.9-1.00.40.50.2-1.7-0.2-0.0-2.00.9
Distance traveled before self-admin0.10.20.4-0.60.60.50.6-0.20.50.40.20.0
Distance traveled after self-admin0.91.74.2-2.01.20.81.3-1.61.01.1-1.20.9
Extensor digitorum longus weight0.41.65.80.50.51.10.51.60.80.11.9-2.4
Bone: elastic displacement0.10.10.4-0.40.20.20.40.00.60.50.30.2
Bone: elastic work0.10.10.4-0.4-0.2-0.40.10.10.40.60.00.4
Bone: endosteal estimation0.51.33.71.5-0.9-0.3-1.11.1-1.4-1.90.4-0.6
Bone: endosteal perimeter1.23.05.22.3-1.7-1.1-1.82.2-1.8-2.11.3-0.9
Epididymis fat weight0.73.47.0-1.22.32.72.2-1.22.02.0-0.5-1.6
Delta time in closed arm before/after self-admin2.42.37.41.2-0.20.2-0.02.40.5-0.12.7-2.3
Delta time in open arm before/after self-admin0.80.92.10.8-1.0-0.8-1.20.6-1.4-1.30.20.4
Diff in mean of infusions in LGA sessions2.34.19.5-2.72.01.62.3-1.22.53.10.8-0.0
Delay discount exponential model param0.60.81.3-0.81.11.21.0-0.70.90.7-0.9-0.3
Extinction: sum of active levers before priming0.50.72.60.7-0.10.2-0.01.20.3-0.21.6-1.3
Active lever presses in extinction session 60.30.30.7-0.3-0.4-0.6-0.2-0.5-0.00.7-0.60.8
Bone: final force0.10.20.40.6-0.7-0.5-0.60.2-0.4-0.4-0.00.3
Bone: final moment0.10.20.40.6-0.6-0.5-0.60.2-0.4-0.4-0.00.2
Food consumed during 24 hour testing period0.81.63.60.6-1.6-1.9-1.40.3-1.9-1.2-0.70.9
Glucose0.10.20.40.4-0.5-0.4-0.50.5-0.4-0.30.6-0.3
Heart weight0.60.92.90.9-0.5-0.1-0.31.60.20.11.7-1.4
Delay discount hyperbolic model param0.70.91.3-0.91.11.21.1-0.71.00.9-0.7-0.4
Intermittent access intake day 1-15 change0.21.02.11.5-1.3-1.4-1.10.9-0.9-0.40.20.3
Intermittent access intake escalation0.31.52.81.6-1.6-1.7-1.40.9-1.3-0.70.00.7
Intermittent access intake escalation 20.50.91.81.2-0.9-1.0-0.9-0.3-1.0-0.6-1.30.7
Intermitt. access day 1 inactive lever presses0.11.65.1-1.20.70.30.7-2.10.40.8-2.31.2
Intermitt. access day 15 inactive lever presses0.21.32.8-1.21.20.91.4-1.21.31.7-0.60.1
Intermitt. access escalation Index0.10.21.1-0.5-0.2-0.5-0.0-0.10.00.70.11.0
Intermittent access day 1 total infusions0.30.81.41.1-1.2-1.1-1.00.9-0.8-0.40.7-0.1
Intermittent access day 15 total infusions1.02.44.91.9-2.1-2.2-1.90.9-1.7-0.80.10.9
Intermittent access terminal intake (last 3 days)0.81.42.71.6-1.5-1.5-1.40.2-1.4-0.7-0.80.6
Intermittent access total infusions0.91.11.91.3-1.3-1.3-1.20.0-1.4-0.7-0.70.6
Intermittent access day 1 locomotion0.20.41.30.1-0.8-1.2-0.6-0.3-0.60.2-0.40.6
Intermittent access day 15 total locomotion0.10.51.30.7-1.0-1.2-0.8-0.2-0.8-0.0-0.60.6
Intermittent access total locomotion0.20.20.60.4-0.6-0.8-0.5-0.4-0.50.2-0.60.2
Intermittent access standard deviation0.00.20.90.30.40.70.3-0.10.2-0.2-0.1-1.0
Left kidney weight0.42.89.8-0.61.92.51.7-0.01.50.70.3-3.1
Right kidney weight0.42.69.3-0.41.82.51.5-0.21.30.4-0.1-3.0
Cocaine induced anxiety0.61.52.7-1.51.41.31.5-0.81.61.40.2-0.5
Post-drug Anxiety0.91.02.8-0.90.70.80.90.61.20.81.7-0.9
Baseline Anxiety0.91.53.41.3-1.2-1.0-1.11.9-0.9-1.01.5-0.7
Tail length0.52.69.9-0.31.62.31.30.81.0-0.11.6-3.1
Length with tail1.14.711.2-1.22.53.32.30.22.11.21.4-3.3
Length without tail0.63.35.4-2.02.12.32.2-0.92.22.00.1-1.4
Times rat made contact with spout0.81.01.5-0.91.21.21.2-0.91.11.0-0.1-0.9
Lifetime Intake1.51.93.11.8-1.6-1.6-1.60.1-1.7-1.1-1.20.6
Liver weight, left0.61.02.1-0.71.21.41.0-1.20.50.5-1.4-0.8
Liver weight, right2.44.29.1-1.72.63.02.3-2.01.91.5-1.0-1.6
Locomotor activity0.61.04.50.30.60.70.70.61.10.61.1-2.1
Locomotor testing distance0.61.67.71.60.10.6-0.01.30.3-0.61.0-2.8
Locomotor testing rearing0.51.88.10.81.11.71.00.51.20.40.7-2.9
Locomotion in novel chamber1.41.94.50.6-1.7-2.0-1.5-0.1-1.6-0.6-0.82.1
Locomotion in novel chamber post-restriction1.13.46.61.8-2.5-2.6-2.21.8-1.8-1.01.01.1
Fecal boli incidents, locomotor time 11.94.96.82.5-2.3-2.5-2.5-0.1-2.6-2.4-2.02.1
Change in fecal boli incidents, locomotor task2.02.13.6-1.81.41.21.60.01.81.91.5-0.7
Time >=10cm from walls, locomotor time 11.11.42.40.6-1.5-1.6-1.40.5-1.6-1.00.11.4
Bouts of movement, locomotor time 10.91.23.70.9-0.8-0.7-0.61.9-0.3-0.51.5-1.5
Total resting periods, locomotor time 10.81.03.10.7-0.9-0.9-0.51.8-0.2-0.21.4-1.1
Rest time, locomotor task time 10.50.81.90.2-1.0-1.4-0.81.3-0.5-0.21.20.1
Distance moved, locomotor task time 10.10.31.10.70.41.00.20.0-0.0-0.6-0.3-0.8
Vertical activity count, locomotor time 10.00.31.00.50.20.90.10.40.1-0.30.1-1.0
Time >=10cm from walls, locomotor time 20.31.02.60.7-1.0-0.7-1.20.3-1.6-1.6-0.30.6
Bouts of movement, locomotor time 20.00.10.40.5-0.2-0.0-0.20.3-0.4-0.6-0.1-0.4
Total resting periods, locomotor time 20.00.10.40.5-0.3-0.1-0.30.2-0.4-0.6-0.3-0.2
Rest time, locomotor task time 20.40.71.5-0.90.70.20.7-1.10.71.0-1.20.4
Distance moved, locomotor task time 20.70.92.31.4-0.8-0.2-1.10.4-1.3-1.5-0.3-0.3
Vertical activity count, locomotor time 20.20.51.31.1-0.40.2-0.60.6-0.7-1.00.0-0.8
Light reinforcement 10.41.83.3-1.01.61.81.6-1.41.51.2-0.6-0.8
Light reinforcement 20.20.41.1-0.60.50.30.4-1.10.30.7-0.50.9
Bone: marrow area0.41.03.01.3-0.7-0.2-1.01.0-1.2-1.70.4-0.6
Bone: maximum diameter0.71.53.01.7-1.0-0.4-1.11.7-1.1-1.31.2-0.9
Bone: maximum force0.30.61.10.6-1.0-1.0-0.90.6-0.8-0.50.20.7
Bone: maximum moment0.30.51.00.7-1.0-0.9-0.90.6-0.8-0.50.30.5
Mean time between licks in bursts0.10.72.51.2-0.5-0.1-0.90.2-1.1-1.6-0.2-0.4
Mean num. licks in bursts0.82.23.71.5-1.7-1.7-1.80.9-1.9-1.80.20.7
Cd content in liver0.91.02.90.00.61.00.61.00.90.31.5-1.7
Co content in liver0.60.72.31.5-0.7-0.4-0.90.6-0.9-1.30.1-0.3
Cu content in liver0.80.93.80.10.81.20.60.60.6-0.11.0-2.0
Fe content in liver0.20.31.00.2-0.1-0.1-0.2-0.6-0.4-0.1-1.00.8
K content in liver0.70.71.9-1.10.80.40.8-1.40.50.6-1.00.2
Mg content in liver0.10.10.3-0.30.1-0.10.1-0.4-0.2-0.1-0.60.1
Mn content in liver0.91.02.9-0.80.2-0.30.3-1.70.00.6-1.71.4
Na content in liver1.11.35.1-0.50.1-0.3-0.1-1.8-0.60.0-2.31.6
Rb content in liver0.50.62.2-0.20.30.50.40.90.60.51.5-1.0
Se content in liver2.63.17.6-2.21.60.91.5-2.71.11.6-2.11.4
Sr content in liver0.60.50.80.9-0.9-0.8-0.90.5-0.9-0.8-0.40.4
Zn content in liver0.91.12.91.5-0.40.0-0.61.2-0.5-1.30.6-1.7
Bone: minimum diameter0.30.51.70.80.00.6-0.30.7-0.6-1.30.4-0.9
Time in familiar zone, hab. session 10.00.00.10.2-0.2-0.3-0.2-0.1-0.20.1-0.30.1
Time in novel zone, hab. session 10.50.61.3-0.40.80.90.70.31.00.31.1-1.0
Total zone transitions, hab. session 10.30.51.1-0.90.20.00.50.50.81.11.0-0.3
Total locomotion distance, hab. session 15.27.412.2-2.73.53.53.2-2.92.72.0-1.8-1.2
Locomotion velocity, hab. session 14.66.610.5-2.73.23.22.9-3.02.31.7-2.2-0.8
Time in familiar zone, hab. session 20.60.61.60.9-0.7-0.6-0.61.1-0.4-0.31.3-0.7
Time in novel zone, hab. session 20.30.31.20.2-0.1-0.0-0.3-0.5-0.5-0.7-1.10.7
Total zone transitions, hab. session 20.40.52.3-0.0-0.1-0.10.11.20.50.71.5-0.5
Total locomotion distance, hab. session 22.93.87.8-1.62.62.82.4-1.42.11.5-0.7-1.5
Locomotion velocity, hab. session 23.34.49.1-1.72.83.02.6-1.32.31.7-0.4-1.8
Novel to familiar place preference ratio0.10.10.3-0.50.40.50.4-0.10.30.20.10.0
Novelty place preference0.00.00.1-0.30.20.30.20.00.20.00.3-0.0
Time in novel zone, NPP test0.10.10.4-0.1-0.10.1-0.00.4-0.0-0.10.6-0.1
Total zone transitions, NPP test0.30.51.10.4-0.9-1.0-0.71.0-0.4-0.00.90.3
Total locomotion distance, NPP test2.13.05.8-1.32.22.21.7-2.41.30.8-2.1-0.2
Locomotion velocity, NPP test2.94.28.2-1.72.52.52.0-2.91.61.1-2.4-0.1
Intraocular pressure2.94.78.52.2-2.9-2.9-2.71.9-2.3-1.70.90.7
Delta distance traveled before/after self-admin0.30.31.0-1.00.40.10.5-0.80.40.5-0.90.1
Delta ambulatory time before/after self-admin0.10.20.6-0.80.1-0.10.3-0.30.50.6-0.2-0.1
Parametrial fat weight1.02.44.3-1.51.92.11.9-0.41.91.40.2-1.3
Pavlov. Cond. lever latency1.01.32.8-0.11.11.21.3-0.21.71.6-0.1-1.3
Pavlov. Cond. magazine entry latency0.81.11.91.2-0.9-0.6-1.11.3-1.0-1.40.8-0.4
Pavlov. Cond. change in total contacts1.61.83.70.6-1.1-1.2-1.4-0.2-1.9-1.7-0.91.8
Pavlov. Cond. index score1.01.23.30.9-1.1-0.9-1.40.8-1.5-1.80.40.4
Pavlov. Cond. latency score0.81.12.80.6-1.0-0.9-1.30.5-1.5-1.70.30.7
Pavlov. Cond. lever contacts0.70.92.30.1-0.8-0.9-1.10.2-1.4-1.5-0.00.9
Pavlov. Cond. magazine entry number1.01.32.3-1.41.00.71.2-1.41.11.5-0.90.3
Pavlov. Cond. intertrial magazine entries0.70.92.0-1.41.00.70.9-1.40.60.7-0.80.7
Pavlov. Cond. lever-magazine prob. diff.1.01.22.90.8-1.1-1.0-1.30.7-1.5-1.70.40.5
Pavlov. Cond. response bias0.50.71.90.7-0.8-0.7-1.00.6-1.1-1.40.20.2
Pavlov. Cond. lever latency10.815.126.9-5.24.23.34.1-5.23.23.5-3.51.5
Pavlov. Cond. magazine entry latency4.86.811.83.2-3.1-2.6-2.93.4-2.2-2.22.2-0.3
Pavlov. Cond. change in total contacts3.79.017.34.0-3.1-2.2-3.14.2-2.4-2.73.0-1.5
Pavlov. Cond. index score8.313.022.84.7-4.0-3.1-3.94.8-3.1-3.33.0-1.0
Pavlov. Cond. latency score7.411.921.24.3-3.9-3.1-3.84.6-3.0-3.13.1-0.8
Pavlov. Cond. lever contacts9.814.528.95.0-4.0-3.0-3.85.4-2.9-3.23.9-1.9
Pavlov. Cond. magazine entry number10.213.220.6-4.54.33.64.2-4.33.53.4-2.50.1
Pavlov. Cond. intertrial magazine entries0.71.63.8-1.01.82.01.5-1.21.00.3-1.0-1.1
Pavlov. Cond. lever-magazine prob. diff.8.012.421.44.6-3.9-3.0-3.84.6-3.1-3.32.9-1.0
Pavlov. Cond. response bias12.016.630.45.5-4.5-3.5-4.45.3-3.5-3.83.2-1.4
Time in closed arm before self-admin0.00.10.4-0.2-0.4-0.6-0.2-0.10.00.3-0.10.1
Time in closed arm after self-admin0.30.41.60.0-0.9-1.3-0.60.5-0.30.30.30.4
Time in open arm before self-admin0.60.81.3-0.51.11.11.0-1.01.00.6-0.9-0.2
Time in open arm after self-admin0.20.20.9-0.10.60.90.5-0.40.1-0.2-0.3-0.4
Bone: periosteal estimation0.71.64.11.8-1.0-0.3-1.31.2-1.5-2.00.3-0.6
Bone: periosteal perimeter0.91.84.71.4-0.7-0.1-0.62.2-0.5-0.92.1-1.8
Bone: post-yield work0.00.10.2-0.40.0-0.10.10.1-0.00.30.30.5
Progressive ratio test 1 active lever presses0.10.20.60.2-0.6-0.8-0.3-0.1-0.30.4-0.40.4
Progressive ratio test 1 breakpoint0.10.20.80.3-0.7-0.9-0.40.0-0.30.4-0.30.5
Progressive ratio test 1 inactive lever presses0.20.41.1-0.50.3-0.10.4-1.00.40.8-1.10.5
Progressive ratio test 2 active lever presses0.71.02.01.3-1.2-1.1-1.20.1-1.4-1.0-0.60.4
Progressive ratio test 2 breakpoint0.91.22.31.3-1.2-1.1-1.30.0-1.5-1.0-0.70.6
Progressive ratio test 2 inactive lever presses0.00.10.40.6-0.4-0.4-0.4-0.1-0.30.0-0.2-0.1
Incentive Sensitization - Responses0.20.71.41.1-0.9-0.6-1.00.4-1.2-1.10.1-0.0
Incentive Sensitization - Breakpoint0.30.61.41.0-0.8-0.6-0.90.2-1.2-1.0-0.20.1
Sum of active levers in priming session hrs 5-60.70.61.1-0.80.90.80.9-0.71.01.00.0-0.4
Progressive ratio0.72.13.41.4-1.8-1.8-1.81.0-1.7-1.7-0.00.6
Food seeking constrained by brief footshock1.01.23.21.8-0.20.4-0.31.5-0.2-1.20.8-1.8
Seeking ratio, punishment vs. effort0.81.74.6-0.61.82.21.5-1.11.10.5-0.9-1.1
Retroperitoneal fat weight3.716.835.9-2.75.06.04.8-1.24.63.20.8-5.0
Reaction time number correct0.10.30.9-0.20.40.00.60.11.00.90.4-0.2
Reaction time mean minus median0.10.61.70.8-0.30.0-0.31.3-0.0-0.61.3-1.1
Reaction time mean minus median AUC0.10.52.00.6-0.4-0.3-0.31.20.0-0.31.4-0.6
Reaction time num false alarms0.40.71.2-1.01.01.11.0-0.40.80.5-0.2-0.8
Reaction time num false alarms AUC0.10.10.4-0.50.40.30.4-0.30.1-0.1-0.6-0.3
Reaction time trials correct on left0.10.30.9-0.20.40.00.60.11.00.90.4-0.2
Reaction time trials on left0.10.30.9-0.20.40.00.60.11.00.90.3-0.2
Reaction time mean0.20.41.2-0.50.81.10.7-0.60.70.3-0.10.0
Reaction time mean AUC0.10.30.8-0.60.70.90.6-0.50.60.4-0.00.2
Median of all reaction times0.40.61.4-0.70.91.10.7-1.20.60.5-0.70.5
Reaction time omissions0.20.30.70.50.20.5-0.00.60.2-0.40.7-0.9
Reaction time false alarm rate0.10.20.8-0.40.20.20.1-0.5-0.3-0.4-0.9-0.0
Reaction time premature initiation rate0.60.93.0-0.11.11.70.7-0.10.4-0.60.2-1.5
Reaction time premature initiations0.20.72.0-0.11.01.40.80.00.7-0.20.3-1.3
Std. dev. reaction times0.10.51.40.50.20.70.10.80.2-0.60.9-1.2
Reaction time trials completed0.10.30.9-0.20.40.00.60.11.00.90.3-0.2
Reaction time trials AUC0.10.31.0-0.10.40.20.60.11.00.80.4-0.4
Run reversals in cocaine runway, females0.91.03.40.10.81.40.70.90.6-0.31.3-1.8
Run reversals in cocaine runway, males1.61.73.81.4-1.5-1.5-1.22.0-0.6-0.41.8-0.3
Latency to leave start box in cocaine runway1.92.75.4-1.81.91.51.5-2.31.11.1-2.00.6
Latency to leave start box in cocaine runway, F1.92.45.7-1.21.91.61.4-2.20.90.6-2.40.1
Latency to leave start box in cocaine runway, M0.60.61.6-1.30.40.20.4-1.00.20.7-0.71.1
Std. dev. time between licks in bursts0.30.72.0-0.31.11.20.8-0.40.50.0-0.2-1.4
Total sessions with >9 infusions1.92.33.71.9-1.6-1.6-1.70.1-1.8-1.6-1.80.3
Short access day 1 total inactive lever presses0.30.71.31.1-1.0-0.9-0.90.7-0.8-0.90.4-0.0
Short access day 10 total inactive lever presses0.42.44.4-1.71.81.62.0-0.82.11.90.4-0.8
Short access day 1 total infusions0.91.73.41.8-1.4-1.1-1.60.4-1.7-1.6-1.00.1
Short access day 10 total infusions1.52.55.32.3-1.7-1.6-1.80.6-1.9-1.8-1.10.2
Short access total infusions1.92.65.22.3-1.8-1.8-1.90.5-1.9-1.6-1.30.2
Short access day 1 locomotion1.52.44.91.8-2.1-2.2-1.91.2-1.6-1.10.30.5
Short access day 10 total locomotion0.20.81.21.1-1.1-1.1-1.00.6-1.0-0.9-0.1-0.5
Short access total locomotion0.40.61.70.6-0.8-1.1-0.7-0.4-0.7-0.3-1.30.4
One hour access (0.3 mA shock)0.60.71.71.3-1.0-0.8-1.00.8-0.8-0.70.2-0.4
Compulsive drug intake0.60.82.8-1.70.70.40.7-0.90.50.9-0.51.2
One hour access (shock baseline)0.82.24.92.2-1.9-1.7-1.80.9-1.5-1.30.00.1
Social response proportion2.12.74.0-1.62.01.81.9-1.61.81.6-1.3-0.5
Social responses1.82.44.6-0.71.82.11.8-0.22.01.40.4-1.9
Social time1.42.23.2-1.41.81.61.7-1.81.61.3-1.4-0.3
Soleus weight0.72.05.6-0.61.62.11.5-0.01.40.50.8-2.4
Bone: stiffness0.10.20.8-0.50.20.20.3-0.00.50.90.40.3
Tibialis anterior weight0.31.03.0-0.30.91.30.90.51.00.50.8-1.7
Time to tail flick, vehicle, before self-admin0.10.10.30.5-0.1-0.0-0.10.5-0.0-0.20.3-0.5
Time to tail flick, vehicle, after self-admin0.61.22.21.5-1.2-1.0-1.21.4-0.9-1.10.8-0.7
Time to tail flick, test, before self-admin1.01.12.11.3-0.9-0.7-0.91.4-1.0-1.40.8-0.5
Time to tail flick, test, after self-admin0.80.82.11.4-0.5-0.1-0.61.1-0.4-1.10.4-1.4
Delta time to tail flick, vehicle, before/after SA0.70.71.30.9-1.1-1.1-1.10.7-0.8-0.70.40.3
Delta time to tail flick, test, before/after SA0.60.81.5-0.81.00.91.0-0.91.21.1-0.5-0.4
Tibia length0.61.83.11.2-1.6-1.5-1.60.7-1.8-1.4-1.10.7
Ambulatory time before self-admin0.00.10.5-0.70.1-0.10.3-0.20.10.30.20.7
Ambulatory time after self-admin0.60.93.3-1.80.60.10.8-1.00.60.9-0.60.9
Bone: tissue strength1.71.74.8-1.90.90.41.2-1.41.22.2-0.21.2
Total heroin consumption0.20.20.4-0.10.40.40.40.00.70.50.4-0.6
Bone: trabecular number0.10.30.6-0.80.2-0.10.4-0.60.40.7-0.00.6
Bone: trabecular spacing0.30.50.80.7-0.7-0.7-0.9-0.0-0.9-0.7-0.60.7
Bone: trabecular thickness1.11.65.0-0.40.60.90.81.41.10.62.2-1.9
Bone: trabecular tissue density2.64.68.3-1.62.32.52.5-0.32.92.51.3-2.3
Water consumed over 24 hours0.40.81.6-1.30.90.81.0-0.71.01.20.3-0.3
Number of responses in last shaping day1.31.73.4-0.91.61.81.3-1.70.80.7-1.7-0.4