Hub : Genes

LOC134484921

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC134484921 0.02 0.02 8.2e-03 0.01 0.02 0.01 0.01 1.1e-02 4.8e-03 1.5e-02 8.8e-03
2 OFC gene expression LOC134484921 0.12 0.08 6.7e-03 0.03 0.04 0.02 0.02 6.3e-02 4.8e-02 1.3e-01 1.3e-01
3 Brain gene expression LOC134484921 0.07 0.04 7.3e-08 0.07 0.08 0.07 0.07 3.2e-07 1.5e-07 4.7e-07 8.8e-07
4 NAcc gene expression LOC134484921 0.09 0.05 2.7e-15 0.11 0.11 0.11 0.11 4.9e-16 3.0e-16 3.2e-16 2.7e-16
5 IC gene expression LOC134484921 0.18 0.1 2.9e-08 0.22 0.15 0.17 0.2 1.8e-09 6.0e-07 9.5e-08 9.4e-09
6 BLA gene expression LOC134484921 0.07 0.05 1.9e-03 0.02 0.03 0.02 0.02 3.4e-02 1.1e-02 2.6e-02 2.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density7.413.615.4-3.7-3.7-3.7-3.93.9-3.1
Area under the delay curve1.01.62.9-1.7-1.3-1.3-1.41.10.0
BMI with tail0.00.10.3-0.1-0.2-0.2-0.40.4-0.5
BMI without tail0.10.40.9-1.0-0.6-0.6-0.80.40.3
Body weight1.35.710.5-3.2-2.6-2.6-2.52.1-0.2
Weight adjusted by age0.10.30.4-0.4-0.5-0.5-0.60.6-0.5
Bone surface5.110.111.3-3.2-3.2-3.2-3.33.4-2.6
Bone volume5.711.312.6-3.5-3.5-3.5-3.53.5-2.6
Breakpoint value in progressive ratio session0.10.20.5-0.6-0.3-0.3-0.40.10.7
Number of licking bursts2.47.211.72.12.62.62.4-2.73.4
Context. condit. distance diff. score2.22.63.4-1.3-1.5-1.5-1.61.8-1.9
Locomotion velocity, session 13.54.05.02.22.22.22.0-1.91.4
Locomotion distance, session 10.60.81.11.01.01.00.8-0.70.7
Locomotion velocity, session 21.72.13.01.71.61.61.4-1.30.9
Locomotion distance, session 21.62.33.41.31.51.51.4-1.41.8
Locomotion velocity, session 30.00.00.1-0.2-0.1-0.1-0.10.10.2
Locomotion distance, session 30.10.10.1-0.4-0.2-0.2-0.20.30.2
Stereotopy head waving bouts, day 30.40.51.3-0.3-0.5-0.6-0.60.7-1.1
Stereotopy head waving duration, day 30.81.01.5-0.8-0.9-0.9-0.91.0-1.2
Locomotion velocity, session 71.21.31.7-1.3-1.2-1.2-1.21.2-0.6
Locomotion distance, session 71.11.42.2-1.5-1.3-1.3-1.21.0-0.6
Stereotopy head waving bouts, day 70.10.10.20.50.40.40.2-0.00.0
Stereotopy head waving duration, day 70.00.00.10.20.20.1-0.20.3-0.2
Locomotion velocity, session 80.10.10.3-0.1-0.2-0.2-0.10.3-0.5
Locomotion distance, session 80.10.10.30.0-0.1-0.1-0.30.5-0.6
Degree of sensitization distance0.40.50.7-0.8-0.8-0.8-0.60.4-0.5
Degree of sensitization stereotypy0.00.00.00.10.10.1-0.10.20.1
Conditioned locomotion0.30.40.6-0.7-0.8-0.7-0.40.4-0.5
Cocaine response after cond. corrected0.81.11.4-1.2-1.1-1.1-1.11.1-0.7
Cocaine response after cond. not corrected1.52.23.2-1.8-1.6-1.6-1.51.4-0.6
Cocaine response before conditioning0.40.51.0-1.0-0.7-0.7-0.70.40.5
Saline control response4.46.17.1-2.7-2.6-2.6-2.52.5-1.9
Bone: connectivity density4.97.89.0-2.6-2.7-2.7-3.03.0-2.6
Bone: cortical apparent density0.00.00.10.30.20.20.10.1-0.3
Bone: cortical area2.94.87.0-2.6-2.3-2.3-2.32.2-0.9
Bone: cortical porosity0.10.10.20.40.40.40.4-0.40.1
Bone: cortical porosity0.00.00.10.10.20.20.2-0.20.3
Bone: cortical thickness0.71.12.3-1.5-1.0-1.0-1.10.90.6
Bone: cortical thickness0.10.10.3-0.4-0.1-0.1-0.20.20.5
Bone: cortical tissue density0.10.10.20.50.30.30.2-0.1-0.2
Condit. Reinf. active minus inactive responses0.70.81.70.60.90.90.8-0.81.3
Condit. Reinf. active-inactive response ratio1.71.82.11.41.41.41.4-1.31.1
Condit. Reinf. active responses0.30.40.7-0.9-0.6-0.6-0.80.70.2
Condit. Reinf. inactive responses2.93.74.7-2.2-1.9-2.0-2.22.0-1.0
Incentive salience index mean0.60.72.40.30.70.70.6-0.71.5
Condit. Reinf. lever presses0.30.41.40.30.50.50.4-0.41.2
Condit. Reinf. active minus inactive responses0.20.30.5-0.7-0.5-0.5-0.60.50.1
Condit. Reinf. active-inactive response ratio0.00.00.0-0.00.10.1-0.00.00.2
Condit. Reinf. active responses1.92.73.8-2.0-1.7-1.7-1.91.6-0.7
Condit. Reinf. inactive responses1.72.53.6-1.9-1.6-1.6-1.71.5-0.6
Condit. Reinf. lever presses0.10.10.2-0.5-0.4-0.4-0.40.3-0.0
Condit. Reinf. lever reinforcers received1.11.62.4-1.6-1.3-1.3-1.51.2-0.4
Conditioned reinforcement - actives1.14.45.4-2.3-2.3-2.3-2.12.0-1.6
Conditioned reinforcement - inactives2.67.07.5-2.6-2.7-2.7-2.72.6-2.5
Conditioned locomotion1.92.83.8-1.5-1.7-1.7-1.61.7-1.9
Patch foraging indifference point 0 sec0.10.31.8-0.20.20.20.2-0.41.3
Patch foraging indifference point AUC0.40.91.6-1.3-0.9-0.9-1.10.90.1
Delay disc. indifference point, 0s delay1.71.93.4-1.9-1.5-1.5-1.51.0-0.2
Delay disc. indifference point, 16s delay2.13.03.9-2.0-1.8-1.8-1.81.9-0.8
Delay disc. indifference point, 2s delay1.21.31.6-1.3-1.2-1.2-1.21.2-0.7
Delay disc. indifference point, 24s delay0.71.22.2-1.5-1.2-1.1-1.01.00.1
Delay disc. indifference point, 4s delay1.71.83.1-1.8-1.4-1.4-1.51.3-0.0
Delay disc. indifference point, 8s delay0.10.20.8-0.6-0.2-0.2-0.4-0.00.9
Indifference point function ln k0.10.20.30.60.40.40.5-0.3-0.2
Indifference point function log k0.10.20.30.60.40.40.5-0.3-0.2
Patch foraging total patch changes 0 sec0.10.31.6-0.30.10.10.1-0.31.3
Patch foraging total patch changes 12 sec0.10.10.6-0.3-0.1-0.1-0.10.10.8
Patch foraging total patch changes 18 sec0.20.40.8-0.9-0.6-0.6-0.70.50.5
Patch foraging total patch changes 24 sec0.10.41.4-0.8-0.3-0.3-0.3-0.01.2
Patch foraging total patch changes 6 sec0.20.31.2-0.7-0.2-0.2-0.30.01.1
Patch foraging time to switch 0 sec1.34.96.02.32.32.32.5-2.21.7
Patch foraging water rate 0 sec0.20.91.0-0.9-1.0-1.0-1.00.8-1.0
Patch foraging water rate 12 sec0.00.10.2-0.5-0.3-0.3-0.1-0.10.4
Patch foraging water rate 18 sec0.10.20.3-0.5-0.5-0.5-0.20.1-0.3
Patch foraging water rate 24 sec1.82.64.2-2.0-1.8-1.8-1.61.4-0.7
Patch foraging water rate 6 sec0.00.10.3-0.1-0.2-0.2-0.1-0.0-0.5
Seeking ratio, delayed vs. immediate footshock0.10.20.30.50.30.30.5-0.6-0.0
Distance traveled before self-admin0.10.10.30.50.50.50.3-0.10.0
Distance traveled after self-admin2.03.55.5-1.4-1.7-1.7-1.72.2-2.3
Extensor digitorum longus weight0.52.12.4-1.5-1.5-1.5-1.51.6-1.0
Bone: elastic displacement3.34.27.42.72.32.32.0-1.80.4
Bone: elastic work1.51.94.32.11.51.51.3-0.9-0.6
Bone: endosteal estimation4.310.511.4-3.2-3.4-3.4-3.23.3-3.0
Bone: endosteal perimeter2.25.56.2-2.1-2.4-2.4-2.32.4-2.5
Epididymis fat weight0.84.04.8-2.2-2.1-2.1-2.12.0-1.4
Delta time in closed arm before/after self-admin6.46.06.82.22.52.52.3-2.62.5
Delta time in open arm before/after self-admin3.64.36.5-1.8-2.0-2.0-1.82.5-2.1
Diff in mean of infusions in LGA sessions0.40.71.11.00.90.90.6-0.90.4
Delay discount exponential model param1.21.62.81.71.31.31.4-1.2-0.1
Extinction: sum of active levers before priming0.10.20.60.20.40.40.3-0.40.8
Active lever presses in extinction session 61.61.62.0-1.4-1.3-1.3-1.41.3-0.7
Bone: final force0.81.42.1-1.5-1.2-1.2-1.21.3-0.2
Bone: final moment0.71.21.7-1.3-1.1-1.1-1.11.2-0.3
Food consumed during 24 hour testing period0.81.53.50.71.01.11.1-1.41.9
Glucose0.30.50.70.80.70.70.8-0.70.2
Heart weight0.00.00.0-0.2-0.1-0.1-0.20.20.1
Delay discount hyperbolic model param1.01.32.21.51.21.21.2-1.1-0.1
Intermittent access intake day 1-15 change0.00.20.3-0.3-0.4-0.4-0.50.2-0.5
Intermittent access intake escalation0.10.40.7-0.4-0.6-0.6-0.70.5-0.8
Intermittent access intake escalation 20.20.40.70.80.70.60.5-0.6-0.1
Intermitt. access day 1 inactive lever presses0.10.70.9-0.8-0.8-0.8-0.90.8-0.9
Intermitt. access day 15 inactive lever presses1.58.39.6-2.7-2.9-2.9-3.12.8-3.0
Intermitt. access escalation Index0.00.00.1-0.1-0.2-0.2-0.00.2-0.3
Intermittent access day 1 total infusions1.75.15.5-2.2-2.4-2.3-2.32.3-2.1
Intermittent access day 15 total infusions2.45.86.3-2.4-2.5-2.5-2.52.3-2.3
Intermittent access terminal intake (last 3 days)2.34.05.1-1.8-2.0-2.0-2.01.8-2.3
Intermittent access total infusions3.44.14.5-1.9-2.1-2.1-1.92.0-2.1
Intermittent access day 1 locomotion1.73.23.4-1.7-1.8-1.8-1.81.8-1.7
Intermittent access day 15 total locomotion0.52.14.3-1.1-1.4-1.4-1.21.2-2.1
Intermittent access total locomotion2.32.74.5-1.3-1.6-1.6-1.51.6-2.1
Intermittent access standard deviation0.21.11.2-1.1-1.1-1.1-1.11.0-1.0
Left kidney weight0.11.22.7-1.6-1.2-1.1-1.10.60.5
Right kidney weight0.10.83.0-1.2-0.5-0.5-0.4-0.21.7
Cocaine induced anxiety0.20.70.8-0.9-0.8-0.8-0.80.9-0.5
Post-drug Anxiety0.40.50.7-0.6-0.6-0.6-0.90.7-0.7
Baseline Anxiety0.10.10.30.40.20.2-0.1-0.2-0.5
Tail length1.36.813.1-3.6-2.9-2.8-2.62.20.0
Length with tail3.113.625.0-5.0-4.1-4.0-3.63.2-0.4
Length without tail2.010.516.2-4.0-3.6-3.5-3.23.1-1.3
Times rat made contact with spout0.60.71.3-1.2-0.9-0.9-1.00.70.0
Lifetime Intake3.44.34.5-2.0-2.1-2.1-2.02.1-2.1
Liver weight, left0.20.40.8-0.9-0.7-0.7-0.50.50.0
Liver weight, right2.13.64.7-2.2-2.0-2.0-2.11.8-1.1
Locomotor activity1.11.72.31.21.31.31.2-1.21.5
Locomotor testing distance0.92.33.11.31.51.51.4-1.51.8
Locomotor testing rearing0.00.10.20.10.20.20.2-0.20.5
Locomotion in novel chamber0.20.31.10.60.20.20.4-0.1-1.0
Locomotion in novel chamber post-restriction0.61.72.3-1.4-1.4-1.4-1.51.3-1.0
Fecal boli incidents, locomotor time 10.20.50.9-0.5-0.7-0.7-0.70.8-1.0
Change in fecal boli incidents, locomotor task0.30.30.90.20.40.40.7-0.50.9
Time >=10cm from walls, locomotor time 12.43.03.9-2.0-1.9-1.8-1.71.7-1.1
Bouts of movement, locomotor time 10.30.41.50.10.40.40.4-0.61.2
Total resting periods, locomotor time 10.20.20.8-0.5-0.2-0.2-0.1-0.00.9
Rest time, locomotor task time 10.00.00.10.10.10.10.10.00.2
Distance moved, locomotor task time 10.00.10.2-0.3-0.1-0.1-0.2-0.30.5
Vertical activity count, locomotor time 10.00.20.30.50.50.50.4-0.50.4
Time >=10cm from walls, locomotor time 20.51.42.4-1.6-1.3-1.3-1.40.9-0.3
Bouts of movement, locomotor time 20.20.71.20.60.70.71.0-0.81.1
Total resting periods, locomotor time 20.21.01.90.70.80.81.2-0.91.4
Rest time, locomotor task time 20.71.22.70.70.90.91.3-0.81.6
Distance moved, locomotor task time 20.30.41.0-0.6-0.6-0.6-1.00.2-0.6
Vertical activity count, locomotor time 20.00.00.10.10.0-0.0-0.3-0.1-0.4
Light reinforcement 10.00.10.1-0.3-0.2-0.2-0.30.4-0.1
Light reinforcement 20.71.62.31.51.41.31.4-1.10.6
Bone: marrow area4.711.412.3-3.3-3.5-3.5-3.43.4-3.2
Bone: maximum diameter6.613.314.2-3.6-3.7-3.7-3.73.8-3.3
Bone: maximum force1.83.54.4-2.0-1.9-1.9-1.92.1-1.2
Bone: maximum moment1.63.03.9-1.8-1.8-1.8-1.82.0-1.1
Mean time between licks in bursts0.74.05.02.22.12.12.0-2.01.3
Mean num. licks in bursts3.28.610.9-2.6-2.9-2.9-2.83.0-3.3
Cd content in liver2.93.23.71.91.81.81.9-1.91.4
Co content in liver0.10.20.50.50.20.20.1-0.0-0.7
Cu content in liver0.20.20.30.40.50.50.5-0.50.6
Fe content in liver1.92.42.71.41.61.51.5-1.61.6
K content in liver0.20.20.30.50.40.40.5-0.40.2
Mg content in liver0.10.10.20.40.30.30.4-0.30.2
Mn content in liver1.31.51.61.21.31.31.1-1.21.2
Na content in liver1.01.11.31.01.11.10.9-1.11.1
Rb content in liver0.00.00.1-0.3-0.2-0.2-0.0-0.20.2
Se content in liver24.629.130.95.25.65.65.4-5.45.3
Sr content in liver0.30.20.60.70.30.30.2-0.0-0.8
Zn content in liver5.15.96.82.52.52.52.6-2.42.1
Bone: minimum diameter3.67.07.8-2.8-2.7-2.7-2.82.7-2.0
Time in familiar zone, hab. session 10.20.20.4-0.4-0.4-0.4-0.50.6-0.3
Time in novel zone, hab. session 11.51.62.01.31.31.31.4-1.41.0
Total zone transitions, hab. session 10.00.00.0-0.1-0.0-0.0-0.00.10.2
Total locomotion distance, hab. session 11.11.61.91.11.21.21.4-1.31.3
Locomotion velocity, hab. session 11.11.51.81.11.21.21.3-1.31.2
Time in familiar zone, hab. session 20.10.10.10.30.30.30.3-0.30.1
Time in novel zone, hab. session 20.00.00.1-0.0-0.1-0.1-0.10.2-0.3
Total zone transitions, hab. session 20.81.02.10.71.01.00.9-0.91.5
Total locomotion distance, hab. session 22.63.43.71.71.91.91.9-1.81.9
Locomotion velocity, hab. session 22.63.54.11.71.91.91.9-1.82.0
Novel to familiar place preference ratio0.81.01.3-1.1-1.0-1.0-1.21.0-0.7
Novelty place preference0.81.01.3-1.0-1.0-1.0-1.11.1-0.9
Time in novel zone, NPP test0.20.20.3-0.5-0.5-0.5-0.60.5-0.3
Total zone transitions, NPP test1.01.53.00.91.21.21.2-1.01.7
Total locomotion distance, NPP test1.42.02.21.31.41.51.4-1.31.5
Locomotion velocity, NPP test0.60.91.50.81.01.00.9-0.81.2
Intraocular pressure0.00.00.0-0.1-0.0-0.00.10.00.2
Delta distance traveled before/after self-admin4.95.46.7-2.0-2.3-2.3-2.22.5-2.6
Delta ambulatory time before/after self-admin5.39.210.3-2.7-3.1-3.1-2.93.1-3.2
Parametrial fat weight0.71.66.10.20.80.80.9-1.22.5
Pavlov. Cond. lever latency0.10.10.6-0.1-0.3-0.3-0.20.3-0.7
Pavlov. Cond. magazine entry latency1.72.22.61.21.41.41.6-1.61.6
Pavlov. Cond. change in total contacts2.12.33.51.21.51.51.3-1.41.9
Pavlov. Cond. index score1.01.32.80.71.01.01.0-1.21.7
Pavlov. Cond. latency score0.50.62.00.30.60.60.6-0.81.4
Pavlov. Cond. lever contacts0.40.51.40.30.60.60.5-0.61.2
Pavlov. Cond. magazine entry number2.43.03.5-1.6-1.7-1.7-1.81.9-1.7
Pavlov. Cond. intertrial magazine entries1.82.12.8-1.7-1.5-1.5-1.61.5-0.7
Pavlov. Cond. lever-magazine prob. diff.1.61.93.41.01.31.31.3-1.41.9
Pavlov. Cond. response bias2.93.64.01.71.91.91.9-2.02.0
Pavlov. Cond. lever latency0.20.30.60.80.70.70.6-0.40.3
Pavlov. Cond. magazine entry latency1.11.62.31.01.21.21.2-1.41.5
Pavlov. Cond. change in total contacts0.20.40.8-0.9-0.7-0.7-0.70.4-0.1
Pavlov. Cond. index score0.10.10.3-0.5-0.3-0.3-0.2-0.10.4
Pavlov. Cond. latency score0.10.10.4-0.6-0.4-0.4-0.30.00.2
Pavlov. Cond. lever contacts0.20.30.5-0.7-0.6-0.6-0.50.4-0.3
Pavlov. Cond. magazine entry number1.01.32.1-0.8-1.0-1.0-1.11.3-1.5
Pavlov. Cond. intertrial magazine entries0.51.11.9-1.4-1.1-1.1-1.11.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.1-0.1-0.0-0.20.6
Pavlov. Cond. response bias0.10.10.5-0.00.20.20.3-0.50.7
Time in closed arm before self-admin0.00.00.1-0.2-0.2-0.2-0.20.1-0.2
Time in closed arm after self-admin1.51.72.31.11.31.31.3-1.41.5
Time in open arm before self-admin1.31.62.01.31.31.31.2-1.40.9
Time in open arm after self-admin1.11.22.1-0.9-1.1-1.1-1.01.4-1.1
Bone: periosteal estimation5.011.813.0-3.6-3.6-3.6-3.53.5-2.7
Bone: periosteal perimeter3.36.67.4-2.7-2.7-2.7-2.62.7-1.9
Bone: post-yield work2.44.16.6-2.6-2.1-2.1-2.22.1-0.3
Progressive ratio test 1 active lever presses3.66.37.9-2.2-2.6-2.5-2.32.6-2.8
Progressive ratio test 1 breakpoint3.35.76.9-2.2-2.5-2.5-2.22.4-2.6
Progressive ratio test 1 inactive lever presses2.66.77.2-2.7-2.7-2.7-2.72.6-2.2
Progressive ratio test 2 active lever presses4.96.97.4-2.5-2.7-2.7-2.52.6-2.7
Progressive ratio test 2 breakpoint5.97.68.1-2.6-2.8-2.8-2.62.8-2.8
Progressive ratio test 2 inactive lever presses1.54.86.2-2.0-2.2-2.2-2.22.0-2.5
Incentive Sensitization - Responses1.02.83.1-1.8-1.7-1.7-1.71.7-1.3
Incentive Sensitization - Breakpoint1.53.33.7-1.9-1.9-1.9-1.81.9-1.5
Sum of active levers in priming session hrs 5-60.10.10.30.30.40.40.1-0.10.5
Progressive ratio0.20.71.20.50.70.70.9-1.11.0
Food seeking constrained by brief footshock0.20.20.50.30.40.40.4-0.70.6
Seeking ratio, punishment vs. effort0.00.00.0-0.1-0.0-0.0-0.10.20.2
Retroperitoneal fat weight0.10.30.6-0.7-0.5-0.5-0.50.40.3
Reaction time number correct1.03.43.9-1.8-1.9-1.9-1.82.0-1.7
Reaction time mean minus median0.10.30.70.80.60.60.7-0.2-0.2
Reaction time mean minus median AUC0.00.20.50.70.50.50.6-0.1-0.2
Reaction time num false alarms0.10.10.3-0.5-0.2-0.2-0.50.00.5
Reaction time num false alarms AUC0.20.41.50.10.50.40.1-0.61.2
Reaction time trials correct on left1.03.43.9-1.8-1.9-1.9-1.82.0-1.7
Reaction time trials on left1.03.33.8-1.8-1.9-1.9-1.82.0-1.6
Reaction time mean2.04.45.62.42.22.22.4-2.01.3
Reaction time mean AUC2.15.26.82.62.42.42.6-2.21.3
Median of all reaction times3.55.46.82.62.42.42.6-2.31.4
Reaction time omissions0.20.30.40.60.60.60.5-0.50.2
Reaction time false alarm rate0.81.22.60.61.01.00.7-1.21.6
Reaction time premature initiation rate0.30.40.9-0.9-0.8-0.8-0.50.4-0.1
Reaction time premature initiations1.02.94.1-2.0-1.9-1.9-1.61.5-1.0
Std. dev. reaction times0.41.41.91.41.21.21.4-1.00.6
Reaction time trials completed1.03.33.8-1.8-1.9-1.9-1.82.0-1.6
Reaction time trials AUC0.82.63.1-1.6-1.7-1.7-1.61.8-1.5
Run reversals in cocaine runway, females0.10.10.20.50.30.30.3-0.1-0.3
Run reversals in cocaine runway, males1.11.22.30.81.01.00.9-1.11.5
Latency to leave start box in cocaine runway0.50.71.7-0.5-0.7-0.7-0.90.7-1.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.1-0.2-0.2-0.40.1-0.5
Latency to leave start box in cocaine runway, M0.50.50.9-0.5-0.7-0.7-0.60.8-0.9
Std. dev. time between licks in bursts3.36.27.62.62.52.52.6-2.71.8
Total sessions with >9 infusions1.01.31.7-1.3-1.2-1.2-1.21.1-0.7
Short access day 1 total inactive lever presses2.03.94.8-1.8-2.0-2.0-2.21.8-2.1
Short access day 10 total inactive lever presses0.42.94.7-2.2-1.8-1.8-2.01.6-0.4
Short access day 1 total infusions1.02.02.2-1.4-1.5-1.5-1.41.5-1.2
Short access day 10 total infusions0.40.61.0-0.7-0.9-0.8-0.70.6-1.0
Short access total infusions2.43.43.7-1.8-1.9-1.9-1.81.9-1.7
Short access day 1 locomotion0.20.40.7-0.5-0.6-0.6-0.60.6-0.8
Short access day 10 total locomotion0.10.40.70.80.70.70.7-0.70.2
Short access total locomotion0.00.10.10.30.20.20.3-0.2-0.1
One hour access (0.3 mA shock)5.66.67.2-2.5-2.7-2.7-2.62.4-2.6
Compulsive drug intake1.31.92.6-1.5-1.4-1.4-1.51.6-0.9
One hour access (shock baseline)0.10.30.6-0.6-0.7-0.7-0.50.1-0.7
Social response proportion0.30.31.50.5-0.0-0.00.20.5-1.2
Social responses0.71.01.7-0.7-0.9-0.9-0.71.2-1.3
Social time0.00.00.1-0.1-0.0-0.00.30.20.3
Soleus weight0.92.74.3-1.3-1.6-1.6-1.61.7-2.1
Bone: stiffness1.73.04.6-2.2-1.8-1.8-1.81.8-0.5
Tibialis anterior weight1.65.46.3-2.3-2.4-2.4-2.42.5-1.9
Time to tail flick, vehicle, before self-admin0.30.40.90.90.60.60.7-0.4-0.3
Time to tail flick, vehicle, after self-admin0.20.31.3-0.6-0.2-0.2-0.4-0.21.2
Time to tail flick, test, before self-admin1.11.31.9-0.8-1.0-1.1-1.01.3-1.4
Time to tail flick, test, after self-admin0.10.10.2-0.4-0.4-0.4-0.30.3-0.3
Delta time to tail flick, vehicle, before/after SA1.82.04.0-2.0-1.4-1.4-1.61.00.5
Delta time to tail flick, test, before/after SA0.10.20.40.20.30.30.3-0.60.6
Tibia length0.20.61.3-1.1-0.8-0.8-0.60.50.3
Ambulatory time before self-admin0.31.01.51.21.11.10.9-0.80.5
Ambulatory time after self-admin2.43.86.5-1.3-1.7-1.8-1.82.3-2.5
Bone: tissue strength0.40.50.50.70.70.70.7-0.50.5
Total heroin consumption0.91.11.9-1.4-1.1-1.1-1.21.0-0.0
Bone: trabecular number4.48.410.0-2.9-2.9-2.9-3.23.0-2.3
Bone: trabecular spacing0.81.22.30.71.01.01.1-1.01.5
Bone: trabecular thickness2.73.84.2-2.1-2.0-2.0-2.02.0-1.5
Bone: trabecular tissue density2.23.94.6-1.8-2.0-2.0-1.82.0-2.1
Water consumed over 24 hours0.10.20.8-0.6-0.2-0.2-0.2-0.00.9
Number of responses in last shaping day1.41.92.6-1.2-1.4-1.4-1.41.2-1.6