Hub : Genes

LOC134483989

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr1_244535817_244536599 0.05 0.04 2.9e-03 0.04 0.03 0.03 0.04 5.8e-04 2.3e-03 1.2e-03 5.2e-04
2 NAcc gene expression LOC134483989 0.07 0.05 1.0e-05 0.04 0.03 0.03 0.04 7.5e-07 7.4e-06 1.6e-05 2.4e-06
3 Adipose gene expression LOC134483989 0.04 0.03 4.7e-04 0.02 0.02 0.01 0.01 2.5e-03 6.5e-03 5.4e-02 4.4e-02
4 Liver gene expression LOC134483989 0.05 0.03 1.8e-03 0 0 -0 0 8.2e-02 1.2e-01 5.8e-01 1.0e-01
5 pVTA gene expression LOC134483989 0.16 0.09 1.5e-05 0.06 0.06 0.04 0.04 5.8e-06 2.5e-05 2.2e-04 1.8e-04
6 LHb intron excision ratio chr1_244535817_244536354 0.47 0.25 9.3e-03 0.02 0.1 0.04 0.05 1.0e-01 2.5e-03 3.4e-02 3.1e-02
7 PL gene expression LOC134483989 0.09 0.04 2.5e-08 0.06 0.07 0.06 0.06 1.4e-07 1.3e-08 4.4e-07 6.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density2.23.94.8-2.1-1.9-2.0-2.0-1.82.2-1.6
Area under the delay curve0.10.10.50.50.10.00.00.1-0.70.0
BMI with tail0.00.10.40.5-0.0-0.0-0.00.6-0.10.3
BMI without tail0.00.10.30.2-0.2-0.3-0.30.1-0.60.0
Body weight0.83.65.3-2.0-2.3-2.2-2.2-1.60.4-1.9
Weight adjusted by age0.00.10.10.20.30.30.3-0.1-0.10.1
Bone surface1.42.68.2-1.8-1.1-1.2-1.2-1.12.9-1.0
Bone volume2.34.15.5-2.3-1.9-2.1-2.1-1.82.2-1.7
Breakpoint value in progressive ratio session0.80.91.3-0.5-1.2-1.1-1.1-0.8-0.6-1.1
Number of licking bursts0.81.21.41.11.11.21.20.9-1.21.0
Context. condit. distance diff. score3.74.55.9-2.1-2.4-2.4-2.4-2.1-0.5-2.3
Locomotion velocity, session 16.16.68.22.62.82.82.82.90.82.6
Locomotion distance, session 10.60.81.20.81.00.90.91.10.10.9
Locomotion velocity, session 21.51.73.01.11.41.41.41.70.91.1
Locomotion distance, session 20.10.10.50.00.40.30.30.2-0.70.2
Locomotion velocity, session 30.40.40.8-0.9-0.7-0.7-0.7-0.6-0.2-0.6
Locomotion distance, session 32.52.74.1-2.0-1.8-1.7-1.7-1.6-0.9-1.6
Stereotopy head waving bouts, day 30.80.91.20.81.10.90.90.91.10.9
Stereotopy head waving duration, day 30.70.81.50.71.00.90.90.81.20.7
Locomotion velocity, session 72.52.84.3-2.0-1.6-1.7-1.7-1.6-0.0-2.1
Locomotion distance, session 72.12.74.1-2.0-1.6-1.6-1.6-1.60.2-2.0
Stereotopy head waving bouts, day 70.40.50.70.70.70.70.70.80.40.9
Stereotopy head waving duration, day 70.60.71.10.70.70.80.80.81.01.0
Locomotion velocity, session 80.20.30.4-0.6-0.6-0.5-0.5-0.30.5-0.6
Locomotion distance, session 81.42.12.4-1.4-1.5-1.5-1.5-1.3-1.1-1.5
Degree of sensitization distance0.10.10.3-0.10.00.00.0-0.20.5-0.6
Degree of sensitization stereotypy0.10.10.40.40.20.30.30.40.20.6
Conditioned locomotion0.60.71.2-0.7-0.9-0.8-0.8-1.1-0.8-0.6
Cocaine response after cond. corrected0.00.00.10.20.00.20.20.10.00.3
Cocaine response after cond. not corrected0.30.30.5-0.4-0.7-0.6-0.6-0.6-0.5-0.4
Cocaine response before conditioning0.30.40.6-0.5-0.6-0.7-0.7-0.6-0.7-0.8
Saline control response0.81.04.1-0.1-0.8-0.8-0.8-0.8-2.0-0.8
Bone: connectivity density1.21.87.4-1.4-0.8-0.9-0.9-0.82.7-0.8
Bone: cortical apparent density1.21.62.51.61.31.41.41.30.41.2
Bone: cortical area3.75.77.6-2.7-2.5-2.6-2.6-2.50.6-2.4
Bone: cortical porosity0.10.10.3-0.40.00.10.1-0.30.5-0.4
Bone: cortical porosity0.20.30.5-0.7-0.3-0.3-0.3-0.50.7-0.7
Bone: cortical thickness1.01.62.2-1.0-1.4-1.5-1.5-1.3-1.0-1.1
Bone: cortical thickness0.10.21.10.20.1-0.0-0.00.0-1.00.1
Bone: cortical tissue density1.41.92.81.71.41.51.51.40.41.2
Condit. Reinf. active minus inactive responses0.10.10.4-0.00.30.20.20.2-0.60.2
Condit. Reinf. active-inactive response ratio1.01.01.50.71.21.21.21.00.41.1
Condit. Reinf. active responses0.60.81.0-0.8-0.9-0.9-0.9-0.9-1.0-0.9
Condit. Reinf. inactive responses1.82.23.0-0.9-1.7-1.7-1.7-1.5-1.1-1.4
Incentive salience index mean0.30.42.8-0.2-0.1-0.1-0.1-0.1-1.7-0.1
Condit. Reinf. lever presses0.50.74.20.60.20.20.20.4-2.10.2
Condit. Reinf. active minus inactive responses1.62.13.4-1.8-1.4-1.4-1.4-1.6-0.5-1.6
Condit. Reinf. active-inactive response ratio0.40.51.0-1.0-0.6-0.5-0.5-0.9-0.5-0.7
Condit. Reinf. active responses1.92.73.7-1.7-1.7-1.8-1.8-1.9-0.4-1.7
Condit. Reinf. inactive responses0.70.91.5-0.5-1.1-1.2-1.2-1.0-0.3-0.7
Condit. Reinf. lever presses0.00.00.10.10.0-0.1-0.1-0.1-0.40.1
Condit. Reinf. lever reinforcers received1.31.82.6-1.4-1.4-1.4-1.4-1.6-0.5-1.3
Conditioned reinforcement - actives0.30.51.8-0.6-0.5-0.5-0.5-0.61.3-0.4
Conditioned reinforcement - inactives0.50.83.5-0.8-0.4-0.4-0.4-0.51.9-0.7
Conditioned locomotion0.60.75.20.00.10.00.0-0.02.3-0.1
Patch foraging indifference point 0 sec0.30.51.00.60.70.50.51.00.40.9
Patch foraging indifference point AUC0.10.10.20.50.40.40.40.2-0.30.2
Delay disc. indifference point, 0s delay1.71.92.3-0.8-1.4-1.5-1.5-1.4-1.5-1.4
Delay disc. indifference point, 16s delay0.00.00.20.30.0-0.0-0.00.00.5-0.0
Delay disc. indifference point, 2s delay0.30.30.70.80.50.40.40.80.10.4
Delay disc. indifference point, 24s delay0.10.10.30.30.10.00.00.2-0.6-0.2
Delay disc. indifference point, 4s delay0.50.51.40.0-0.7-0.7-0.7-0.4-1.2-0.6
Delay disc. indifference point, 8s delay1.11.32.01.41.31.21.21.1-0.81.1
Indifference point function ln k0.50.81.5-1.2-0.8-1.0-1.0-0.60.7-0.8
Indifference point function log k0.50.81.5-1.2-0.8-1.0-1.0-0.60.7-0.8
Patch foraging total patch changes 0 sec0.20.50.90.60.60.50.51.00.50.9
Patch foraging total patch changes 12 sec1.51.93.31.81.31.31.31.6-0.51.5
Patch foraging total patch changes 18 sec0.40.71.71.30.80.50.51.0-0.50.8
Patch foraging total patch changes 24 sec0.00.00.1-0.3-0.2-0.0-0.0-0.2-0.1-0.2
Patch foraging total patch changes 6 sec1.11.72.41.31.41.41.41.60.21.5
Patch foraging time to switch 0 sec0.61.32.51.30.81.01.00.9-1.61.2
Patch foraging water rate 0 sec0.30.61.8-0.8-0.3-0.5-0.5-0.31.3-0.8
Patch foraging water rate 12 sec0.20.30.7-0.7-0.3-0.5-0.5-0.40.8-0.5
Patch foraging water rate 18 sec0.71.11.7-1.3-1.1-1.1-1.1-0.70.6-1.2
Patch foraging water rate 24 sec1.82.53.5-1.5-1.8-1.9-1.9-1.5-0.4-1.6
Patch foraging water rate 6 sec0.20.31.50.20.40.40.40.51.20.2
Seeking ratio, delayed vs. immediate footshock0.20.30.8-0.5-0.5-0.3-0.3-0.9-0.5-0.5
Distance traveled before self-admin0.00.00.0-0.10.00.20.2-0.0-0.1-0.1
Distance traveled after self-admin0.70.94.20.20.60.70.70.72.10.1
Extensor digitorum longus weight1.76.58.1-2.5-2.7-2.8-2.8-2.5-1.2-2.8
Bone: elastic displacement4.55.27.02.42.62.52.52.50.72.2
Bone: elastic work2.83.65.11.72.32.02.02.11.41.7
Bone: endosteal estimation3.06.511.0-3.2-2.2-2.2-2.2-2.23.3-2.4
Bone: endosteal perimeter2.65.68.2-2.9-2.2-2.2-2.2-2.12.8-2.1
Epididymis fat weight0.41.21.8-1.0-1.3-1.3-1.3-0.80.7-1.2
Delta time in closed arm before/after self-admin0.20.20.50.10.50.40.40.40.70.2
Delta time in open arm before/after self-admin0.00.00.10.10.10.20.20.4-0.20.0
Diff in mean of infusions in LGA sessions0.60.71.1-0.8-0.8-0.9-0.9-0.70.9-1.0
Delay discount exponential model param0.10.10.4-0.5-0.1-0.0-0.0-0.20.6-0.0
Extinction: sum of active levers before priming0.91.01.5-1.0-1.1-1.1-1.1-0.80.4-1.2
Active lever presses in extinction session 62.82.83.9-1.8-1.8-1.6-1.6-2.0-0.6-1.8
Bone: final force1.32.13.5-1.9-1.4-1.5-1.5-1.50.8-1.3
Bone: final moment0.81.42.4-1.5-1.0-1.1-1.1-1.11.3-0.9
Food consumed during 24 hour testing period0.00.10.3-0.00.20.00.00.5-0.00.3
Glucose0.10.20.4-0.4-0.1-0.2-0.2-0.50.7-0.4
Heart weight1.93.08.11.31.51.41.41.72.81.4
Delay discount hyperbolic model param0.10.10.3-0.6-0.3-0.2-0.2-0.40.5-0.2
Intermittent access intake day 1-15 change0.51.02.4-1.3-0.8-0.8-0.8-0.91.5-0.2
Intermittent access intake escalation0.61.32.4-1.6-1.1-1.1-1.1-1.21.1-0.5
Intermittent access intake escalation 20.60.72.3-1.5-0.6-0.6-0.6-0.80.9-0.2
Intermitt. access day 1 inactive lever presses0.20.91.60.81.21.21.20.90.50.7
Intermitt. access day 15 inactive lever presses0.61.38.4-0.40.10.10.1-0.52.9-0.3
Intermitt. access escalation Index0.20.31.30.80.20.10.10.3-1.20.3
Intermittent access day 1 total infusions0.50.71.9-0.7-0.7-0.7-0.7-0.51.4-1.0
Intermittent access day 15 total infusions1.82.73.2-1.7-1.7-1.7-1.7-1.71.8-1.3
Intermittent access terminal intake (last 3 days)1.21.64.0-1.3-1.1-1.1-1.1-1.02.0-0.8
Intermittent access total infusions1.31.52.3-1.0-1.2-1.3-1.3-1.11.5-1.1
Intermittent access day 1 locomotion0.30.41.0-0.3-0.6-0.6-0.6-0.51.0-0.7
Intermittent access day 15 total locomotion0.40.73.6-0.3-0.5-0.6-0.6-0.41.9-0.3
Intermittent access total locomotion0.70.92.2-0.6-0.8-0.9-0.9-0.71.5-0.9
Intermittent access standard deviation0.81.75.2-1.5-0.9-0.9-0.9-1.02.3-0.8
Left kidney weight0.41.92.9-1.3-1.6-1.7-1.7-1.30.3-1.2
Right kidney weight0.21.01.8-0.9-1.3-1.2-1.2-0.9-0.3-0.8
Cocaine induced anxiety0.50.81.3-0.7-0.9-0.9-0.9-1.1-1.0-0.7
Post-drug Anxiety0.10.10.40.1-0.3-0.2-0.2-0.6-0.10.0
Baseline Anxiety0.30.41.60.40.40.40.40.31.30.4
Tail length1.14.35.3-2.3-2.3-2.2-2.2-2.2-0.3-2.3
Length with tail1.77.59.6-3.1-3.1-3.0-3.0-2.80.6-2.9
Length without tail2.47.810.3-3.0-3.2-3.1-3.1-2.61.1-3.0
Times rat made contact with spout0.20.20.80.2-0.3-0.5-0.50.2-0.9-0.5
Lifetime Intake1.11.43.0-1.0-1.1-1.1-1.1-1.01.7-1.1
Liver weight, left0.60.91.3-1.0-1.1-1.1-1.1-1.10.1-0.9
Liver weight, right1.01.72.0-1.3-1.4-1.4-1.4-1.21.2-1.2
Locomotor activity0.50.81.40.80.90.90.91.20.01.0
Locomotor testing distance1.01.82.51.11.51.51.51.60.41.4
Locomotor testing rearing0.20.40.9-1.0-0.6-0.6-0.6-0.7-0.3-0.7
Locomotion in novel chamber0.60.81.2-1.0-1.0-1.1-1.1-0.7-0.1-0.9
Locomotion in novel chamber post-restriction2.43.95.6-1.5-2.4-2.4-2.4-2.2-1.0-1.8
Fecal boli incidents, locomotor time 10.60.91.3-1.0-1.0-0.8-0.8-1.2-0.2-1.2
Change in fecal boli incidents, locomotor task0.20.20.50.70.30.40.40.6-0.50.6
Time >=10cm from walls, locomotor time 15.76.07.9-2.5-2.8-2.7-2.7-2.5-0.8-2.4
Bouts of movement, locomotor time 10.40.41.0-0.2-0.7-0.5-0.5-0.9-1.0-0.2
Total resting periods, locomotor time 10.50.61.2-0.2-0.8-0.7-0.7-1.1-1.0-0.4
Rest time, locomotor task time 10.20.20.40.60.40.70.7-0.00.00.4
Distance moved, locomotor task time 10.30.40.7-0.8-0.5-0.8-0.8-0.2-0.4-0.7
Vertical activity count, locomotor time 10.00.10.2-0.3-0.0-0.4-0.40.1-0.10.1
Time >=10cm from walls, locomotor time 21.21.82.3-1.5-1.5-1.3-1.3-1.5-1.0-1.3
Bouts of movement, locomotor time 20.91.42.31.50.71.11.11.2-1.51.1
Total resting periods, locomotor time 20.71.22.81.20.61.01.00.9-1.70.9
Rest time, locomotor task time 20.60.82.7-0.4-0.8-0.5-0.5-1.0-1.6-0.4
Distance moved, locomotor task time 20.40.50.8-0.8-0.4-0.8-0.8-0.20.4-0.9
Vertical activity count, locomotor time 20.50.71.50.31.00.60.61.11.20.5
Light reinforcement 10.00.10.20.30.30.30.30.30.10.4
Light reinforcement 23.04.76.22.22.52.52.52.30.42.1
Bone: marrow area3.16.711.4-3.2-2.2-2.2-2.2-2.23.4-2.4
Bone: maximum diameter5.510.314.5-3.8-3.3-3.3-3.3-3.22.3-3.0
Bone: maximum force1.62.84.3-2.1-1.5-1.7-1.7-1.61.7-1.4
Bone: maximum moment1.22.14.8-1.8-1.1-1.3-1.3-1.22.2-1.1
Mean time between licks in bursts1.02.43.71.11.81.91.91.21.11.6
Mean num. licks in bursts0.81.31.7-1.0-1.2-1.3-1.3-1.00.8-1.3
Cd content in liver2.62.93.81.61.81.91.91.90.51.9
Co content in liver3.03.44.41.72.02.02.02.11.11.9
Cu content in liver4.85.77.22.62.52.52.52.71.12.5
Fe content in liver1.21.42.21.51.01.11.11.1-1.01.4
K content in liver0.30.32.10.0-0.1-0.1-0.1-0.1-1.5-0.4
Mg content in liver0.40.40.60.70.60.60.60.7-0.80.5
Mn content in liver1.61.73.21.81.31.21.21.4-0.81.3
Na content in liver0.50.52.90.60.30.30.30.1-1.70.2
Rb content in liver0.30.30.4-0.6-0.6-0.6-0.6-0.30.5-0.6
Se content in liver19.523.128.65.25.35.25.25.0-1.54.9
Sr content in liver2.62.32.91.21.71.71.71.31.41.5
Zn content in liver3.23.64.82.02.12.02.02.2-1.21.6
Bone: minimum diameter5.910.816.1-4.0-3.3-3.3-3.3-3.32.4-3.2
Time in familiar zone, hab. session 10.40.41.20.40.40.50.50.61.10.5
Time in novel zone, hab. session 10.10.10.4-0.10.20.10.1-0.0-0.6-0.1
Total zone transitions, hab. session 10.00.00.0-0.10.10.00.00.10.20.0
Total locomotion distance, hab. session 10.40.61.60.70.70.50.50.8-1.30.6
Locomotion velocity, hab. session 10.60.83.40.80.70.40.40.7-1.80.6
Time in familiar zone, hab. session 21.31.31.71.01.21.21.21.31.01.1
Time in novel zone, hab. session 20.10.10.2-0.2-0.3-0.3-0.3-0.4-0.1-0.3
Total zone transitions, hab. session 20.50.60.80.70.60.90.90.90.10.9
Total locomotion distance, hab. session 20.40.60.70.80.70.80.80.9-0.50.8
Locomotion velocity, hab. session 20.30.41.00.70.50.50.50.7-1.00.6
Novel to familiar place preference ratio1.01.01.7-1.3-0.8-1.1-1.1-1.10.2-1.2
Novelty place preference0.91.01.7-1.3-0.7-1.0-1.0-1.00.4-1.2
Time in novel zone, NPP test0.80.91.7-1.3-0.6-0.9-0.9-1.00.6-1.1
Total zone transitions, NPP test0.10.20.50.20.20.40.40.4-0.70.2
Total locomotion distance, NPP test0.71.02.11.01.00.90.90.8-1.40.8
Locomotion velocity, NPP test0.60.83.10.80.70.70.70.6-1.80.5
Intraocular pressure0.00.00.10.20.10.00.00.00.30.2
Delta distance traveled before/after self-admin0.70.83.6-0.7-0.4-0.5-0.5-0.31.9-0.6
Delta ambulatory time before/after self-admin0.80.93.8-0.8-0.6-0.7-0.7-0.51.9-0.8
Parametrial fat weight0.10.31.8-0.1-0.3-0.2-0.2-0.1-1.3-0.4
Pavlov. Cond. lever latency1.01.33.41.00.90.90.90.91.91.2
Pavlov. Cond. magazine entry latency0.20.20.50.20.40.20.20.7-0.70.3
Pavlov. Cond. change in total contacts0.30.30.50.20.70.60.60.6-0.30.5
Pavlov. Cond. index score0.60.73.3-0.5-0.5-0.6-0.6-0.3-1.8-0.6
Pavlov. Cond. latency score1.01.24.6-0.8-0.8-0.9-0.9-0.6-2.1-0.9
Pavlov. Cond. lever contacts0.60.73.3-0.5-0.5-0.5-0.5-0.5-1.8-0.7
Pavlov. Cond. magazine entry number0.10.10.4-0.2-0.4-0.2-0.2-0.70.2-0.4
Pavlov. Cond. intertrial magazine entries0.70.91.5-0.6-1.0-0.9-0.9-1.2-1.1-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.63.4-0.3-0.3-0.4-0.4-0.1-1.9-0.3
Pavlov. Cond. response bias0.30.40.80.40.80.60.60.9-0.30.6
Pavlov. Cond. lever latency0.30.40.7-0.6-0.6-0.6-0.6-0.8-0.5-0.7
Pavlov. Cond. magazine entry latency0.30.40.60.40.70.80.80.7-0.40.6
Pavlov. Cond. change in total contacts0.00.10.3-0.10.0-0.1-0.10.1-0.6-0.2
Pavlov. Cond. index score0.00.00.1-0.00.10.10.10.2-0.30.1
Pavlov. Cond. latency score0.00.00.1-0.2-0.0-0.0-0.00.0-0.2-0.0
Pavlov. Cond. lever contacts0.20.30.50.60.50.50.50.70.50.6
Pavlov. Cond. magazine entry number0.40.50.7-0.5-0.7-0.8-0.8-0.70.8-0.5
Pavlov. Cond. intertrial magazine entries1.82.63.6-1.4-1.8-1.9-1.9-1.7-0.9-1.6
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.00.10.10.10.2-0.40.1
Pavlov. Cond. response bias0.40.50.90.60.80.80.80.90.10.7
Time in closed arm before self-admin0.10.10.30.20.00.10.10.3-0.6-0.1
Time in closed arm after self-admin0.20.20.70.30.40.30.30.3-0.9-0.0
Time in open arm before self-admin0.60.71.30.41.10.90.90.50.80.9
Time in open arm after self-admin0.20.30.40.20.50.50.50.40.60.6
Bone: periosteal estimation4.08.412.6-3.6-2.8-2.8-2.8-2.72.7-2.8
Bone: periosteal perimeter3.96.69.0-3.0-2.7-2.8-2.8-2.61.3-2.5
Bone: post-yield work2.53.65.6-2.4-2.0-1.9-1.9-2.01.4-1.7
Progressive ratio test 1 active lever presses0.60.72.9-0.6-0.6-0.6-0.6-0.41.7-0.5
Progressive ratio test 1 breakpoint0.50.62.6-0.6-0.5-0.6-0.6-0.41.6-0.5
Progressive ratio test 1 inactive lever presses0.60.84.2-1.0-0.2-0.2-0.2-0.42.0-0.6
Progressive ratio test 2 active lever presses2.22.66.6-1.6-1.4-1.3-1.3-1.32.6-1.2
Progressive ratio test 2 breakpoint2.42.77.2-1.6-1.4-1.4-1.4-1.32.7-1.3
Progressive ratio test 2 inactive lever presses0.50.85.2-0.6-0.1-0.1-0.1-0.32.3-0.3
Incentive Sensitization - Responses1.42.04.9-1.6-1.2-1.1-1.1-1.12.2-1.0
Incentive Sensitization - Breakpoint1.62.14.9-1.6-1.3-1.2-1.2-1.22.2-1.1
Sum of active levers in priming session hrs 5-61.81.73.21.41.21.31.31.80.41.3
Progressive ratio1.01.64.1-0.6-1.2-1.2-1.2-1.4-2.0-0.7
Food seeking constrained by brief footshock2.32.84.3-2.0-1.7-1.8-1.8-2.1-0.4-1.4
Seeking ratio, punishment vs. effort0.30.42.1-0.40.30.30.30.41.5-0.0
Retroperitoneal fat weight0.00.20.7-0.0-0.3-0.1-0.10.20.8-0.5
Reaction time number correct0.71.31.9-1.3-1.4-1.2-1.2-1.2-0.3-1.0
Reaction time mean minus median0.20.61.70.20.70.70.70.71.30.8
Reaction time mean minus median AUC0.61.51.80.81.31.31.31.21.11.4
Reaction time num false alarms1.92.63.5-1.5-1.9-1.7-1.7-1.6-1.0-1.7
Reaction time num false alarms AUC1.32.12.7-1.4-1.6-1.5-1.5-1.5-0.9-1.5
Reaction time trials correct on left0.71.31.9-1.3-1.4-1.2-1.2-1.2-0.3-1.0
Reaction time trials on left0.71.31.9-1.3-1.4-1.2-1.2-1.2-0.4-1.0
Reaction time mean1.52.53.31.21.81.81.81.71.11.4
Reaction time mean AUC2.03.24.31.42.12.02.02.01.01.7
Median of all reaction times1.92.73.81.31.91.91.91.81.01.4
Reaction time omissions0.10.10.2-0.40.30.40.4-0.00.00.2
Reaction time false alarm rate0.60.81.0-0.7-1.0-0.9-0.9-0.9-0.7-1.0
Reaction time premature initiation rate1.01.41.9-1.1-1.4-1.4-1.4-1.1-0.8-1.0
Reaction time premature initiations2.13.85.4-1.9-2.3-2.2-2.2-2.0-1.0-1.6
Std. dev. reaction times1.01.82.30.81.41.41.41.41.51.4
Reaction time trials completed0.71.31.9-1.3-1.4-1.2-1.2-1.2-0.4-1.0
Reaction time trials AUC0.61.21.7-1.2-1.3-1.1-1.1-1.1-0.5-1.0
Run reversals in cocaine runway, females1.21.21.70.91.31.21.21.20.81.0
Run reversals in cocaine runway, males0.30.31.50.50.00.00.0-0.4-1.20.3
Latency to leave start box in cocaine runway0.50.60.9-0.9-0.9-0.9-0.9-0.60.1-0.8
Latency to leave start box in cocaine runway, F0.50.61.2-1.1-0.8-0.7-0.7-0.70.2-0.9
Latency to leave start box in cocaine runway, M0.10.10.2-0.2-0.4-0.4-0.40.1-0.2-0.2
Std. dev. time between licks in bursts2.33.13.91.91.92.02.01.80.51.8
Total sessions with >9 infusions0.50.61.61.00.50.50.50.71.30.3
Short access day 1 total inactive lever presses0.40.63.7-0.20.30.30.30.11.9-0.0
Short access day 10 total inactive lever presses0.00.10.70.00.10.10.1-0.3-0.8-0.1
Short access day 1 total infusions0.40.51.30.70.70.60.60.51.20.4
Short access day 10 total infusions0.70.92.00.70.90.90.90.91.40.5
Short access total infusions0.40.53.5-0.1-0.0-0.1-0.1-0.11.9-0.4
Short access day 1 locomotion0.60.70.90.90.90.80.81.01.00.4
Short access day 10 total locomotion0.20.40.70.60.80.70.70.9-0.20.5
Short access total locomotion1.92.23.01.71.61.61.61.71.31.0
One hour access (0.3 mA shock)3.94.56.9-2.5-2.0-2.0-2.0-1.92.6-1.7
Compulsive drug intake0.40.50.8-0.8-0.6-0.6-0.6-0.90.2-0.8
One hour access (shock baseline)1.11.72.6-1.4-1.3-1.3-1.3-1.11.6-1.0
Social response proportion0.40.42.1-0.20.30.60.60.21.50.1
Social responses0.60.84.9-0.30.10.30.30.02.20.0
Social time0.20.30.60.30.70.80.80.1-0.00.4
Soleus weight0.61.87.2-1.6-0.5-0.6-0.6-0.82.7-1.0
Bone: stiffness4.47.29.7-3.1-2.8-2.8-2.8-3.10.5-2.7
Tibialis anterior weight2.58.310.4-3.0-2.9-3.0-3.0-3.1-1.7-3.2
Time to tail flick, vehicle, before self-admin2.02.12.91.51.71.71.71.30.51.2
Time to tail flick, vehicle, after self-admin3.03.95.0-1.7-1.9-2.0-2.0-2.2-1.7-2.1
Time to tail flick, test, before self-admin1.11.11.7-1.2-1.1-1.0-1.0-0.61.1-1.3
Time to tail flick, test, after self-admin0.50.61.00.61.00.90.90.8-0.10.4
Delta time to tail flick, vehicle, before/after SA11.811.213.8-3.1-3.6-3.6-3.6-3.7-2.3-3.3
Delta time to tail flick, test, before/after SA0.60.60.80.80.90.80.80.4-0.70.8
Tibia length0.00.10.3-0.2-0.4-0.5-0.50.30.3-0.1
Ambulatory time before self-admin0.20.30.50.40.60.70.70.4-0.20.3
Ambulatory time after self-admin0.50.53.5-0.20.20.20.20.41.9-0.3
Bone: tissue strength0.90.93.50.20.90.90.90.61.90.5
Total heroin consumption0.91.11.7-0.9-1.3-1.3-1.3-0.80.0-1.1
Bone: trabecular number1.11.95.3-1.3-1.2-1.2-1.2-0.92.3-0.9
Bone: trabecular spacing0.40.62.90.50.40.50.50.3-1.70.4
Bone: trabecular thickness1.51.93.0-1.5-1.3-1.4-1.4-1.01.7-1.2
Bone: trabecular tissue density0.60.91.4-0.8-1.1-1.2-1.2-0.90.2-1.0
Water consumed over 24 hours0.50.71.2-0.7-0.7-0.9-0.9-0.4-1.1-1.1
Number of responses in last shaping day1.61.82.91.71.11.11.11.01.71.4