Hub : Genes

LOC134483971

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC134483971 0.33 0.16 5.5e-06 0.17 0.15 0.19 0.19 7.9e-05 1.9e-04 3.5e-05 3.2e-05
2 NAcc gene expression LOC134483971 0.48 0.08 0.0e+00 0.7 0.72 0.72 0.72 8.8e-150 1.6e-157 8.9e-158 6.1e-157
3 IL gene expression LOC134483971 0.23 0.13 6.8e-04 0.09 0.11 0.01 0.07 3.9e-03 1.2e-03 1.4e-01 1.0e-02
4 NAcc mRNA stability LOC134483971 0.01 0.01 5.3e-03 0.02 0.02 0.02 0.02 1.4e-03 1.3e-03 1.2e-03 1.5e-03
5 pVTA gene expression LOC134483971 0.09 0.05 4.4e-07 0.07 0.08 0.08 0.07 4.3e-06 3.3e-07 6.2e-07 2.8e-06
6 BLA gene expression LOC134483971 0.22 0.1 4.0e-12 0.21 0.24 0.24 0.23 2.0e-11 8.0e-13 1.0e-12 1.1e-12
7 Brain gene expression LOC134483971 0.74 0 0.0e+00 0.56 0.55 0.56 0.56 9.4e-63 2.5e-61 4.3e-63 1.5e-63
8 PL gene expression LOC134483971 0.19 0.09 2.4e-15 0.1 0.14 0.13 0.13 4.9e-11 5.2e-15 7.9e-14 6.1e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.30.5-0.60.4-0.50.5-0.7-0.6-0.3-0.6
Area under the delay curve0.00.00.2-0.1-0.0-0.10.1-0.4-0.30.1-0.2
BMI with tail4.214.820.0-2.93.8-3.93.5-4.1-4.2-3.8-4.5
BMI without tail0.52.83.6-1.21.5-1.71.7-1.8-1.8-1.6-1.9
Body weight4.017.720.8-4.04.1-4.33.9-4.6-4.5-3.9-4.4
Weight adjusted by age1.13.34.5-1.32.0-1.91.7-1.6-1.8-2.1-2.0
Bone surface1.02.03.6-1.91.3-1.41.1-1.7-1.5-1.0-1.2
Bone volume0.30.71.3-1.10.7-0.80.5-1.1-0.9-0.4-0.8
Breakpoint value in progressive ratio session1.42.53.7-1.91.7-1.61.7-1.4-1.3-1.6-1.1
Number of licking bursts0.00.10.20.00.1-0.30.3-0.4-0.4-0.1-0.4
Context. condit. distance diff. score0.00.10.10.30.2-0.20.1-0.2-0.3-0.2-0.4
Locomotion velocity, session 10.10.20.4-0.20.6-0.30.5-0.0-0.2-0.6-0.5
Locomotion distance, session 11.31.62.3-1.01.5-1.21.4-1.0-1.2-1.5-1.4
Locomotion velocity, session 23.03.63.8-1.91.9-1.91.7-1.9-1.9-1.9-1.8
Locomotion distance, session 20.91.32.1-0.71.2-1.11.3-0.9-1.0-1.5-1.2
Locomotion velocity, session 31.01.22.1-0.50.9-1.10.7-1.4-1.4-0.9-1.5
Locomotion distance, session 30.20.20.5-0.0-0.60.4-0.50.30.40.70.6
Stereotopy head waving bouts, day 30.30.30.80.20.4-0.50.4-0.6-0.7-0.6-0.9
Stereotopy head waving duration, day 30.40.51.00.10.6-0.70.6-0.8-0.9-0.8-1.0
Locomotion velocity, session 70.00.00.1-0.1-0.1-0.1-0.0-0.3-0.20.1-0.1
Locomotion distance, session 70.00.00.00.1-0.1-0.1-0.1-0.2-0.2-0.0-0.2
Stereotopy head waving bouts, day 70.20.20.3-0.50.5-0.50.4-0.5-0.5-0.4-0.5
Stereotopy head waving duration, day 70.91.22.0-1.41.1-1.11.0-1.1-1.0-1.0-0.8
Locomotion velocity, session 80.10.20.40.0-0.40.3-0.30.40.50.30.7
Locomotion distance, session 80.10.20.40.30.3-0.30.3-0.3-0.4-0.5-0.6
Degree of sensitization distance1.21.32.7-0.11.1-1.11.0-1.1-1.3-1.3-1.6
Degree of sensitization stereotypy0.91.01.5-1.21.1-1.00.9-1.0-1.0-1.0-0.9
Conditioned locomotion0.60.70.8-0.80.8-0.90.9-0.9-0.9-0.8-0.8
Cocaine response after cond. corrected0.10.20.50.70.3-0.20.40.0-0.3-0.5-0.7
Cocaine response after cond. not corrected0.10.10.30.50.3-0.10.20.2-0.1-0.4-0.6
Cocaine response before conditioning0.10.10.6-0.80.10.1-0.40.20.30.20.4
Saline control response1.62.24.4-2.11.6-1.51.5-1.4-1.2-1.4-1.0
Bone: connectivity density1.22.02.5-1.61.4-1.41.4-1.5-1.4-1.2-1.3
Bone: cortical apparent density0.10.10.5-0.70.4-0.30.4-0.2-0.2-0.40.0
Bone: cortical area0.20.31.3-1.10.4-0.40.2-0.5-0.4-0.1-0.2
Bone: cortical porosity0.00.00.1-0.1-0.0-0.00.10.10.2-0.10.3
Bone: cortical porosity0.00.10.1-0.30.2-0.20.3-0.1-0.0-0.30.1
Bone: cortical thickness1.11.85.4-2.31.4-1.31.5-1.0-0.8-1.2-0.5
Bone: cortical thickness0.00.10.3-0.50.0-0.10.20.10.20.00.3
Bone: cortical tissue density0.20.30.7-0.90.6-0.50.6-0.4-0.3-0.6-0.1
Condit. Reinf. active minus inactive responses1.61.82.5-1.21.6-1.31.4-1.0-1.2-1.5-1.4
Condit. Reinf. active-inactive response ratio0.91.01.7-0.81.3-0.91.3-0.4-0.7-1.3-0.9
Condit. Reinf. active responses1.72.22.9-1.21.7-1.51.4-1.2-1.4-1.6-1.7
Condit. Reinf. inactive responses0.20.20.6-0.00.4-0.40.1-0.5-0.6-0.3-0.8
Incentive salience index mean1.21.51.9-1.21.4-1.21.1-1.1-1.2-1.2-1.3
Condit. Reinf. lever presses0.30.40.8-0.90.6-0.60.2-0.8-0.7-0.4-0.7
Condit. Reinf. active minus inactive responses0.00.00.10.10.2-0.00.30.1-0.1-0.1-0.3
Condit. Reinf. active-inactive response ratio0.20.41.20.40.5-0.50.4-0.6-0.8-0.5-1.1
Condit. Reinf. active responses0.10.10.2-0.40.4-0.20.4-0.1-0.2-0.2-0.3
Condit. Reinf. inactive responses0.30.50.9-0.4-0.40.6-0.40.80.90.71.0
Condit. Reinf. lever presses1.01.51.8-1.21.3-1.21.1-1.3-1.3-1.0-1.3
Condit. Reinf. lever reinforcers received0.30.40.6-0.70.7-0.50.8-0.4-0.5-0.5-0.6
Conditioned reinforcement - actives0.00.10.20.2-0.10.3-0.40.50.40.30.2
Conditioned reinforcement - inactives0.10.20.5-0.10.4-0.40.1-0.5-0.6-0.3-0.7
Conditioned locomotion0.71.12.01.4-1.11.0-1.30.80.71.10.5
Patch foraging indifference point 0 sec0.10.40.7-0.80.7-0.60.5-0.7-0.6-0.7-0.4
Patch foraging indifference point AUC0.30.81.9-1.40.9-0.80.9-0.8-0.7-0.8-0.5
Delay disc. indifference point, 0s delay0.10.20.60.50.0-0.20.0-0.4-0.50.1-0.8
Delay disc. indifference point, 16s delay0.00.10.1-0.30.3-0.20.1-0.4-0.3-0.2-0.2
Delay disc. indifference point, 2s delay0.20.20.50.5-0.60.5-0.70.10.20.70.2
Delay disc. indifference point, 24s delay0.00.00.0-0.1-0.1-0.00.1-0.2-0.10.10.0
Delay disc. indifference point, 4s delay0.20.20.5-0.40.1-0.40.3-0.7-0.5-0.1-0.4
Delay disc. indifference point, 8s delay0.20.40.70.7-0.80.6-0.60.40.50.70.7
Indifference point function ln k0.72.05.42.3-1.41.3-1.51.21.01.30.6
Indifference point function log k0.72.05.42.3-1.41.3-1.51.21.01.30.6
Patch foraging total patch changes 0 sec0.10.30.6-0.80.6-0.60.4-0.5-0.4-0.6-0.3
Patch foraging total patch changes 12 sec4.25.68.8-3.02.5-2.42.4-2.2-2.1-2.5-1.7
Patch foraging total patch changes 18 sec0.20.41.0-1.00.7-0.60.8-0.4-0.4-0.6-0.3
Patch foraging total patch changes 24 sec2.17.08.4-2.92.7-2.72.6-2.8-2.6-2.5-2.4
Patch foraging total patch changes 6 sec0.40.71.4-1.20.8-0.90.6-1.0-0.8-0.7-0.6
Patch foraging time to switch 0 sec0.20.71.0-0.70.8-0.80.5-1.0-1.0-0.6-1.0
Patch foraging water rate 0 sec0.41.51.90.9-1.21.2-1.21.31.41.11.4
Patch foraging water rate 12 sec0.52.13.01.7-1.51.5-1.41.51.41.31.2
Patch foraging water rate 18 sec0.40.81.00.9-1.00.9-1.00.80.80.90.8
Patch foraging water rate 24 sec1.21.72.01.4-1.31.3-1.31.31.31.21.2
Patch foraging water rate 6 sec1.21.72.01.3-1.41.3-1.11.31.41.21.3
Seeking ratio, delayed vs. immediate footshock0.20.30.7-0.20.4-0.60.4-0.7-0.8-0.3-0.8
Distance traveled before self-admin1.02.23.2-1.81.5-1.51.3-1.6-1.5-1.3-1.4
Distance traveled after self-admin0.30.50.7-0.80.7-0.70.9-0.6-0.6-0.7-0.6
Extensor digitorum longus weight6.425.727.1-5.15.1-5.25.1-5.1-5.0-5.0-4.8
Bone: elastic displacement0.40.61.10.7-0.60.7-0.41.01.00.40.9
Bone: elastic work0.40.51.1-1.00.7-0.70.9-0.4-0.4-0.7-0.3
Bone: endosteal estimation0.41.02.31.5-1.10.8-1.40.30.31.20.1
Bone: endosteal perimeter0.71.83.71.9-1.51.2-1.90.60.51.60.4
Epididymis fat weight0.20.92.01.4-1.00.9-1.40.40.31.10.2
Delta time in closed arm before/after self-admin2.42.33.2-1.21.5-1.61.8-1.4-1.4-1.5-1.5
Delta time in open arm before/after self-admin1.61.92.3-1.51.5-1.41.3-1.3-1.3-1.4-1.2
Diff in mean of infusions in LGA sessions1.52.73.3-1.81.7-1.71.8-1.6-1.5-1.6-1.4
Delay discount exponential model param0.00.00.20.10.00.1-0.00.40.3-0.10.1
Extinction: sum of active levers before priming2.23.34.2-2.01.8-1.81.7-1.9-1.8-1.9-1.4
Active lever presses in extinction session 61.81.83.2-1.81.5-1.31.1-1.3-1.2-1.4-0.9
Bone: final force0.81.32.5-1.61.1-1.10.8-1.2-1.1-0.9-1.0
Bone: final moment0.81.32.5-1.61.1-1.10.8-1.2-1.1-0.9-1.0
Food consumed during 24 hour testing period0.30.60.80.4-0.70.8-0.80.90.90.80.8
Glucose1.21.84.12.0-1.41.4-1.41.21.11.30.6
Heart weight0.10.20.50.7-0.2-0.1-0.2-0.4-0.50.2-0.6
Delay discount hyperbolic model param0.00.00.10.00.20.00.10.30.2-0.20.1
Intermittent access intake day 1-15 change0.41.92.21.2-1.31.5-1.51.41.41.41.3
Intermittent access intake escalation0.42.02.31.4-1.31.5-1.51.51.41.41.3
Intermittent access intake escalation 20.30.50.60.5-0.60.7-0.80.70.70.70.6
Intermitt. access day 1 inactive lever presses0.00.20.60.8-0.30.4-0.40.50.30.30.2
Intermitt. access day 15 inactive lever presses0.42.03.1-1.21.3-1.40.8-1.6-1.7-1.2-1.8
Intermitt. access escalation Index0.31.01.21.1-1.11.0-1.00.80.91.00.9
Intermittent access day 1 total infusions0.20.72.10.20.4-0.60.1-1.0-1.2-0.4-1.4
Intermittent access day 15 total infusions0.71.73.01.7-1.31.3-1.71.00.81.40.6
Intermittent access terminal intake (last 3 days)0.10.20.40.6-0.20.2-0.6-0.2-0.30.3-0.6
Intermittent access total infusions0.20.20.50.7-0.20.2-0.6-0.2-0.40.3-0.6
Intermittent access day 1 locomotion0.40.81.9-0.10.7-0.80.4-1.0-1.2-0.7-1.4
Intermittent access day 15 total locomotion0.20.92.3-0.20.8-0.80.3-1.1-1.2-0.7-1.5
Intermittent access total locomotion0.81.03.0-0.00.7-0.80.1-1.2-1.4-0.6-1.7
Intermittent access standard deviation0.00.20.40.7-0.40.5-0.50.60.50.40.3
Left kidney weight0.00.30.60.6-0.70.4-0.8-0.1-0.10.8-0.1
Right kidney weight0.00.10.20.5-0.40.2-0.5-0.1-0.10.4-0.2
Cocaine induced anxiety0.00.00.1-0.20.3-0.20.10.0-0.0-0.2-0.1
Post-drug Anxiety0.30.30.4-0.60.6-0.60.5-0.5-0.6-0.6-0.7
Baseline Anxiety0.10.20.4-0.50.4-0.50.5-0.6-0.5-0.4-0.5
Tail length0.10.31.1-1.10.4-0.50.8-0.4-0.2-0.20.0
Length with tail0.94.16.9-2.61.9-2.12.1-2.2-1.9-1.6-1.6
Length without tail1.58.110.8-3.32.9-2.92.8-2.9-2.7-2.7-2.6
Times rat made contact with spout0.10.10.5-0.40.4-0.30.7-0.1-0.1-0.3-0.1
Lifetime Intake0.10.20.50.6-0.1-0.0-0.4-0.3-0.50.1-0.7
Liver weight, left0.71.21.71.3-1.11.1-0.91.21.11.01.0
Liver weight, right1.12.02.41.5-1.41.5-1.41.51.41.41.1
Locomotor activity1.01.62.21.0-1.31.3-0.91.41.51.11.4
Locomotor testing distance0.51.21.81.1-1.11.2-0.81.31.30.91.1
Locomotor testing rearing0.31.22.01.1-1.01.2-0.81.41.30.91.0
Locomotion in novel chamber1.31.72.51.3-1.41.4-1.61.11.11.31.1
Locomotion in novel chamber post-restriction0.61.72.51.6-1.31.3-1.11.41.31.21.2
Fecal boli incidents, locomotor time 10.00.00.20.20.2-0.00.10.1-0.10.1-0.5
Change in fecal boli incidents, locomotor task1.71.82.31.3-1.51.3-1.51.11.21.41.2
Time >=10cm from walls, locomotor time 10.50.61.81.4-0.60.7-1.00.50.30.70.1
Bouts of movement, locomotor time 10.60.81.8-0.91.1-0.91.3-0.5-0.6-0.8-0.7
Total resting periods, locomotor time 10.50.51.1-0.90.9-0.71.0-0.5-0.5-0.5-0.6
Rest time, locomotor task time 10.71.12.01.4-1.01.0-1.10.90.81.10.6
Distance moved, locomotor task time 10.00.10.3-0.60.3-0.30.2-0.4-0.3-0.6-0.1
Vertical activity count, locomotor time 10.21.42.20.9-1.21.2-1.31.21.30.91.5
Time >=10cm from walls, locomotor time 20.10.20.30.3-0.40.5-0.50.50.50.50.5
Bouts of movement, locomotor time 21.54.96.5-1.42.5-2.32.4-1.8-2.2-2.4-2.6
Total resting periods, locomotor time 21.14.36.3-1.02.3-2.12.2-1.7-2.1-2.2-2.5
Rest time, locomotor task time 20.50.93.51.9-0.80.9-0.70.90.60.60.3
Distance moved, locomotor task time 20.10.20.5-0.7-0.10.2-0.20.20.40.20.7
Vertical activity count, locomotor time 20.61.53.50.3-1.11.2-1.11.21.50.91.9
Light reinforcement 10.10.30.50.2-0.40.6-0.50.70.70.60.5
Light reinforcement 20.20.41.00.4-0.70.5-0.90.20.31.00.3
Bone: marrow area0.51.32.81.7-1.31.0-1.60.50.51.40.3
Bone: maximum diameter0.10.10.3-0.40.0-0.2-0.2-0.5-0.40.2-0.3
Bone: maximum force1.42.84.1-2.01.6-1.71.2-2.0-1.8-1.3-1.7
Bone: maximum moment1.52.84.1-2.01.6-1.71.2-1.9-1.8-1.3-1.6
Mean time between licks in bursts0.10.71.4-0.20.9-0.81.0-0.6-0.8-1.2-0.9
Mean num. licks in bursts0.10.10.40.0-0.10.3-0.10.70.60.10.5
Cd content in liver0.80.91.10.8-0.91.0-1.11.01.00.90.9
Co content in liver1.11.31.90.9-1.21.1-1.01.31.31.01.4
Cu content in liver0.10.20.30.1-0.50.3-0.40.30.40.40.5
Fe content in liver0.00.00.00.10.0-0.1-0.0-0.1-0.1-0.0-0.1
K content in liver0.20.20.4-0.50.4-0.50.2-0.6-0.6-0.4-0.5
Mg content in liver0.00.00.0-0.00.00.00.0-0.1-0.1-0.1-0.2
Mn content in liver2.62.93.4-1.81.7-1.81.6-1.8-1.7-1.7-1.5
Na content in liver0.10.10.3-0.60.4-0.20.3-0.1-0.2-0.3-0.3
Rb content in liver2.32.73.61.9-1.71.7-1.61.71.61.61.4
Se content in liver0.30.40.6-0.40.6-0.60.4-0.8-0.8-0.5-0.7
Sr content in liver5.64.85.9-2.22.3-2.22.4-2.0-2.0-2.3-2.0
Zn content in liver2.42.83.5-1.91.7-1.71.7-1.6-1.5-1.8-1.4
Bone: minimum diameter0.30.51.11.0-0.80.6-1.00.20.20.90.0
Time in familiar zone, hab. session 10.00.00.1-0.30.3-0.20.1-0.2-0.2-0.1-0.2
Time in novel zone, hab. session 11.21.31.61.3-1.11.2-1.11.31.21.01.0
Total zone transitions, hab. session 10.10.20.4-0.60.5-0.40.6-0.3-0.3-0.5-0.2
Total locomotion distance, hab. session 10.20.30.70.00.5-0.50.5-0.5-0.7-0.6-0.8
Locomotion velocity, hab. session 10.60.91.2-0.61.0-0.91.0-0.9-1.0-1.1-1.1
Time in familiar zone, hab. session 21.11.21.50.7-1.01.1-1.01.21.21.11.2
Time in novel zone, hab. session 20.91.01.2-0.91.0-1.00.9-1.0-1.0-1.0-1.1
Total zone transitions, hab. session 20.60.81.5-1.21.0-0.81.0-0.7-0.7-0.9-0.7
Total locomotion distance, hab. session 20.40.50.7-0.40.8-0.60.8-0.5-0.7-0.8-0.8
Locomotion velocity, hab. session 20.20.30.6-0.20.6-0.50.6-0.5-0.6-0.6-0.7
Novel to familiar place preference ratio1.21.62.2-1.41.1-1.41.2-1.5-1.3-1.1-1.1
Novelty place preference0.81.01.5-1.10.8-1.10.9-1.2-1.1-0.9-0.9
Time in novel zone, NPP test1.31.62.0-1.21.1-1.31.2-1.4-1.3-1.2-1.2
Total zone transitions, NPP test0.71.11.8-1.31.2-1.01.2-0.8-0.7-1.3-0.7
Total locomotion distance, NPP test0.10.10.2-0.40.4-0.30.4-0.2-0.2-0.4-0.2
Locomotion velocity, NPP test0.00.00.1-0.2-0.00.1-0.00.10.2-0.00.3
Intraocular pressure0.00.00.10.30.00.00.20.20.1-0.00.0
Delta distance traveled before/after self-admin0.30.30.70.8-0.50.5-0.20.70.60.30.5
Delta ambulatory time before/after self-admin0.40.61.11.0-0.70.8-0.41.00.90.60.8
Parametrial fat weight1.22.95.61.9-2.01.6-2.40.70.92.21.1
Pavlov. Cond. lever latency0.30.31.01.0-0.60.5-0.30.60.50.40.4
Pavlov. Cond. magazine entry latency0.81.11.4-1.21.1-1.00.7-1.1-1.1-0.9-1.1
Pavlov. Cond. change in total contacts0.20.20.6-0.70.6-0.40.2-0.4-0.4-0.4-0.4
Pavlov. Cond. index score0.30.30.9-0.90.7-0.50.3-0.6-0.5-0.4-0.4
Pavlov. Cond. latency score0.10.20.7-0.80.5-0.40.1-0.4-0.3-0.2-0.3
Pavlov. Cond. lever contacts0.10.10.4-0.70.3-0.2-0.1-0.3-0.2-0.1-0.1
Pavlov. Cond. magazine entry number0.50.61.21.1-0.90.8-0.70.80.70.70.6
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.3-0.20.3-0.00.50.50.10.6
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.90.8-0.60.4-0.6-0.6-0.5-0.5
Pavlov. Cond. response bias0.60.71.3-1.11.0-0.80.6-0.8-0.8-0.7-0.7
Pavlov. Cond. lever latency1.52.13.01.0-1.51.4-1.51.41.51.31.7
Pavlov. Cond. magazine entry latency6.38.810.4-3.03.2-3.03.0-2.8-2.9-3.0-2.9
Pavlov. Cond. change in total contacts1.22.93.8-1.71.9-1.71.7-1.6-1.7-1.6-1.9
Pavlov. Cond. index score4.16.57.5-2.32.7-2.62.5-2.5-2.6-2.4-2.7
Pavlov. Cond. latency score3.96.27.2-2.22.6-2.52.5-2.4-2.6-2.3-2.7
Pavlov. Cond. lever contacts1.42.13.0-1.01.6-1.41.5-1.3-1.5-1.3-1.7
Pavlov. Cond. magazine entry number10.513.715.63.6-4.03.8-3.83.53.73.63.6
Pavlov. Cond. intertrial magazine entries1.43.13.51.5-1.81.8-1.71.81.91.71.9
Pavlov. Cond. lever-magazine prob. diff.4.57.08.2-2.52.9-2.72.6-2.5-2.7-2.5-2.8
Pavlov. Cond. response bias3.65.06.0-1.92.4-2.22.3-2.1-2.3-2.1-2.4
Time in closed arm before self-admin0.10.10.40.1-0.30.3-0.50.20.20.60.2
Time in closed arm after self-admin0.50.60.80.8-0.80.8-0.70.70.70.90.6
Time in open arm before self-admin1.41.72.31.2-1.41.3-1.01.41.41.01.5
Time in open arm after self-admin0.10.20.3-0.60.3-0.40.5-0.2-0.2-0.60.0
Bone: periosteal estimation0.10.20.50.2-0.40.1-0.7-0.3-0.20.6-0.1
Bone: periosteal perimeter0.00.10.30.0-0.20.2-0.5-0.1-0.00.4-0.1
Bone: post-yield work0.10.20.50.2-0.30.1-0.7-0.5-0.40.6-0.3
Progressive ratio test 1 active lever presses0.00.00.10.3-0.10.0-0.2-0.1-0.20.1-0.2
Progressive ratio test 1 breakpoint0.00.00.10.3-0.00.0-0.1-0.1-0.20.0-0.3
Progressive ratio test 1 inactive lever presses1.23.24.2-1.31.8-1.81.5-1.9-2.0-1.8-2.1
Progressive ratio test 2 active lever presses0.10.20.40.6-0.30.3-0.70.1-0.00.5-0.2
Progressive ratio test 2 breakpoint0.10.10.40.6-0.30.3-0.6-0.0-0.10.4-0.3
Progressive ratio test 2 inactive lever presses0.00.10.30.30.0-0.0-0.4-0.3-0.40.1-0.6
Incentive Sensitization - Responses0.41.22.0-0.71.0-1.10.8-1.2-1.3-0.9-1.4
Incentive Sensitization - Breakpoint0.41.01.8-0.60.9-1.00.6-1.2-1.2-0.8-1.4
Sum of active levers in priming session hrs 5-60.40.31.0-1.00.7-0.50.6-0.4-0.3-0.7-0.1
Progressive ratio0.10.20.50.00.3-0.40.0-0.6-0.6-0.1-0.7
Food seeking constrained by brief footshock0.00.00.10.3-0.10.1-0.10.20.10.2-0.0
Seeking ratio, punishment vs. effort0.00.00.10.1-0.10.10.20.30.2-0.10.2
Retroperitoneal fat weight2.19.315.43.9-3.43.1-3.62.32.33.22.1
Reaction time number correct0.00.10.6-0.80.4-0.30.5-0.1-0.0-0.1-0.0
Reaction time mean minus median0.10.50.9-0.91.0-0.70.7-0.5-0.5-0.9-0.4
Reaction time mean minus median AUC0.00.20.3-0.50.6-0.30.50.10.0-0.60.1
Reaction time num false alarms0.30.50.80.6-0.80.7-0.40.80.80.70.9
Reaction time num false alarms AUC0.10.20.60.1-0.50.4-0.10.50.60.40.8
Reaction time trials correct on left0.00.10.6-0.80.4-0.30.5-0.1-0.0-0.1-0.0
Reaction time trials on left0.00.20.7-0.80.4-0.30.5-0.1-0.0-0.1-0.0
Reaction time mean0.00.10.3-0.10.5-0.20.30.1-0.1-0.6-0.2
Reaction time mean AUC0.00.00.10.10.30.00.00.30.1-0.30.0
Median of all reaction times0.10.10.3-0.10.5-0.30.3-0.1-0.2-0.6-0.3
Reaction time omissions0.10.20.6-0.80.5-0.40.6-0.2-0.2-0.50.0
Reaction time false alarm rate0.20.30.50.6-0.70.5-0.40.50.60.50.7
Reaction time premature initiation rate2.74.26.0-2.41.9-2.21.4-2.4-2.2-1.8-1.9
Reaction time premature initiations1.54.48.0-2.82.0-2.21.7-2.3-2.0-1.8-1.7
Std. dev. reaction times0.00.10.2-0.00.20.20.00.40.4-0.20.4
Reaction time trials completed0.00.20.7-0.80.4-0.30.5-0.1-0.0-0.1-0.0
Reaction time trials AUC0.00.10.5-0.70.3-0.20.5-0.00.0-0.1-0.0
Run reversals in cocaine runway, females0.30.30.6-0.40.3-0.50.3-0.8-0.7-0.5-0.6
Run reversals in cocaine runway, males1.71.92.80.9-1.51.4-1.31.31.51.41.7
Latency to leave start box in cocaine runway0.30.51.00.6-0.80.6-1.00.20.31.00.3
Latency to leave start box in cocaine runway, F0.10.10.2-0.20.1-0.2-0.1-0.5-0.40.1-0.4
Latency to leave start box in cocaine runway, M2.32.22.91.6-1.61.5-1.61.21.31.71.2
Std. dev. time between licks in bursts0.10.30.40.7-0.50.5-0.70.50.50.50.4
Total sessions with >9 infusions0.10.10.50.7-0.00.0-0.1-0.0-0.2-0.1-0.4
Short access day 1 total inactive lever presses0.00.00.10.10.0-0.10.1-0.3-0.3-0.1-0.3
Short access day 10 total inactive lever presses0.00.20.60.8-0.30.4-0.10.70.50.10.3
Short access day 1 total infusions0.20.51.31.1-0.70.7-0.70.60.50.60.4
Short access day 10 total infusions0.20.41.30.20.4-0.40.0-0.7-0.9-0.4-1.1
Short access total infusions0.10.10.40.60.0-0.1-0.2-0.3-0.4-0.1-0.6
Short access day 1 locomotion0.00.00.10.3-0.10.1-0.20.00.00.20.0
Short access day 10 total locomotion0.41.53.4-0.31.1-1.20.8-1.3-1.5-1.2-1.9
Short access total locomotion0.40.61.6-0.00.7-0.70.4-0.9-1.0-0.7-1.3
One hour access (0.3 mA shock)0.20.30.70.9-0.50.4-0.80.1-0.00.6-0.2
Compulsive drug intake0.30.51.0-0.60.7-0.71.0-0.4-0.4-0.9-0.4
One hour access (shock baseline)0.92.34.01.7-1.61.5-2.01.11.11.80.9
Social response proportion0.50.61.0-0.1-0.80.7-0.90.50.81.01.0
Social responses0.60.71.6-0.1-0.80.7-0.70.81.00.91.3
Social time0.20.30.60.1-0.30.4-0.00.80.80.30.8
Soleus weight2.98.49.83.1-2.93.0-2.83.02.92.82.6
Bone: stiffness0.20.30.8-0.90.4-0.50.2-0.7-0.6-0.2-0.4
Tibialis anterior weight8.027.634.2-5.95.5-5.35.5-5.0-4.8-5.5-4.4
Time to tail flick, vehicle, before self-admin0.30.40.7-0.30.5-0.60.4-0.8-0.8-0.4-0.8
Time to tail flick, vehicle, after self-admin0.61.32.0-0.81.1-1.21.0-1.2-1.3-1.0-1.4
Time to tail flick, test, before self-admin0.20.20.4-0.10.2-0.40.2-0.7-0.6-0.3-0.6
Time to tail flick, test, after self-admin0.00.10.10.0-0.20.2-0.30.30.30.10.3
Delta time to tail flick, vehicle, before/after SA0.50.50.6-0.70.8-0.80.8-0.6-0.7-0.7-0.8
Delta time to tail flick, test, before/after SA0.10.10.2-0.20.10.10.00.50.4-0.10.5
Tibia length0.92.44.8-2.21.5-1.61.2-1.7-1.5-1.3-1.2
Ambulatory time before self-admin0.41.42.6-1.61.2-1.20.9-1.2-1.1-1.0-1.0
Ambulatory time after self-admin0.10.20.3-0.50.4-0.40.3-0.4-0.4-0.3-0.4
Bone: tissue strength0.90.91.20.9-0.91.0-1.11.01.01.00.9
Total heroin consumption3.84.47.4-2.72.2-2.22.3-1.9-1.7-2.3-1.3
Bone: trabecular number0.81.51.9-1.21.1-1.21.1-1.4-1.3-1.0-1.2
Bone: trabecular spacing0.50.71.50.7-0.60.8-0.51.21.10.60.8
Bone: trabecular thickness0.20.30.40.5-0.60.5-0.60.30.40.60.4
Bone: trabecular tissue density3.76.47.12.7-2.62.6-2.42.62.52.42.4
Water consumed over 24 hours0.10.20.7-0.80.3-0.50.4-0.5-0.4-0.2-0.1
Number of responses in last shaping day0.40.50.8-0.80.7-0.70.9-0.6-0.6-0.8-0.5