Hub : Genes

LOC134483967

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC134483967 0.26 0.12 1.6e-05 0.07 0.16 0.14 0.14 1.1e-02 1.4e-04 3.9e-04 4.2e-04
2 NAcc gene expression LOC134483967 0.03 0.02 1.2e-05 0.04 0.04 0.04 0.04 4.4e-06 3.9e-06 3.3e-06 4.3e-06
3 IL gene expression LOC134483967 0.18 0.11 1.9e-03 0.12 0.11 0.1 0.1 1.0e-03 1.5e-03 2.8e-03 2.1e-03
4 Brain gene expression LOC134483967 0.12 0.06 8.9e-13 0.14 0.14 0.13 0.14 4.9e-13 1.0e-12 2.8e-12 1.5e-12
5 BLA gene expression LOC134483967 0.1 0.06 2.5e-05 0.05 0.08 0.06 0.07 9.5e-04 5.3e-05 2.6e-04 1.1e-04
6 pVTA gene expression LOC134483967 0.03 0.02 3.4e-03 0.01 0.02 0.01 0.02 7.3e-02 6.7e-03 2.4e-02 1.6e-02
7 Adipose gene expression LOC134483967 0.06 0.04 1.5e-06 0.04 0.05 0.04 0.04 9.6e-06 4.9e-06 2.6e-05 1.1e-05
8 LHb gene expression LOC134483967 0.16 0.09 1.9e-03 0.1 0.08 0.08 0.09 2.2e-03 6.0e-03 7.4e-03 4.5e-03
9 PL gene expression LOC134483967 0.1 0.06 2.6e-11 0.08 0.09 0.1 0.1 2.0e-09 7.1e-10 4.7e-11 5.1e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.50.91.3-1.0-1.1-0.7-0.8-1.1-0.9-1.1-0.7-0.8
Area under the delay curve0.10.10.50.0-0.2-0.1-0.1-0.2-0.2-0.3-0.4-0.7
BMI with tail3.010.514.3-3.0-3.8-2.8-2.8-3.6-3.2-3.6-2.6-3.6
BMI without tail0.61.83.2-0.8-1.5-1.1-1.0-1.3-1.3-1.5-1.4-1.8
Body weight3.615.819.9-3.7-4.5-3.8-3.8-4.1-4.1-4.3-3.8-3.6
Weight adjusted by age0.81.11.6-1.3-1.3-1.1-1.1-1.2-1.1-1.1-0.7-0.5
Bone surface2.74.96.9-2.6-2.6-2.1-2.2-2.6-2.2-2.4-1.7-0.9
Bone volume1.32.33.9-2.0-1.8-1.3-1.4-1.9-1.5-1.7-1.0-0.4
Breakpoint value in progressive ratio session1.82.13.0-1.7-1.4-1.7-1.7-1.4-1.6-1.4-1.4-0.4
Number of licking bursts0.00.10.3-0.1-0.3-0.20.0-0.0-0.0-0.1-0.40.5
Context. condit. distance diff. score0.20.30.70.80.60.80.70.50.50.40.0-0.0
Locomotion velocity, session 10.10.10.70.60.30.10.10.2-0.0-0.0-0.4-0.8
Locomotion distance, session 10.60.71.6-0.4-0.6-0.6-0.6-0.7-0.9-0.9-1.2-1.2
Locomotion velocity, session 22.52.93.4-1.7-1.7-1.7-1.6-1.8-1.8-1.8-1.8-1.5
Locomotion distance, session 20.10.20.9-0.1-0.2-0.3-0.3-0.3-0.5-0.5-0.9-0.4
Locomotion velocity, session 30.50.50.9-0.5-0.9-0.5-0.3-0.9-0.7-0.9-0.9-0.7
Locomotion distance, session 30.10.10.30.1-0.2-0.2-0.2-0.1-0.2-0.2-0.4-0.5
Stereotopy head waving bouts, day 30.10.10.30.1-0.10.60.5-0.20.2-0.1-0.20.3
Stereotopy head waving duration, day 30.10.10.50.20.10.50.5-0.00.20.0-0.40.7
Locomotion velocity, session 70.00.00.1-0.2-0.10.20.2-0.3-0.1-0.2-0.40.1
Locomotion distance, session 70.10.10.50.50.10.40.40.20.10.0-0.2-0.7
Stereotopy head waving bouts, day 70.30.30.7-0.9-0.6-0.4-0.4-0.8-0.5-0.6-0.50.3
Stereotopy head waving duration, day 71.62.02.5-1.6-1.5-1.4-1.4-1.6-1.4-1.5-1.4-0.4
Locomotion velocity, session 80.20.20.60.80.60.40.30.60.20.3-0.40.1
Locomotion distance, session 80.20.20.70.50.40.80.80.30.50.3-0.00.1
Degree of sensitization distance0.10.10.4-0.1-0.40.30.2-0.4-0.1-0.3-0.1-0.6
Degree of sensitization stereotypy1.11.22.2-1.5-1.2-1.1-1.0-1.3-1.0-1.1-0.8-0.2
Conditioned locomotion0.60.70.8-0.7-0.8-0.8-0.9-0.7-0.8-0.8-0.9-0.8
Cocaine response after cond. corrected0.60.81.71.31.11.10.71.00.80.70.1-0.2
Cocaine response after cond. not corrected0.40.51.01.00.80.80.60.70.60.60.4-0.2
Cocaine response before conditioning0.40.51.1-1.0-0.8-0.9-0.7-0.8-0.6-0.60.40.2
Saline control response2.53.35.0-1.4-1.9-2.0-1.9-1.6-2.0-1.9-2.2-1.5
Bone: connectivity density2.13.34.2-1.8-2.0-1.7-1.8-2.0-1.9-2.0-1.5-1.3
Bone: cortical apparent density0.20.20.7-0.4-0.0-0.5-0.7-0.2-0.5-0.3-0.90.0
Bone: cortical area1.11.62.4-1.5-1.5-1.3-1.2-1.5-1.2-1.3-0.9-0.8
Bone: cortical porosity0.10.10.50.10.50.20.10.30.20.4-0.10.7
Bone: cortical porosity0.00.10.20.00.3-0.1-0.10.2-0.00.1-0.40.4
Bone: cortical thickness2.44.05.8-1.6-1.8-2.4-2.3-1.6-2.2-1.9-2.3-1.6
Bone: cortical thickness0.30.41.20.0-0.2-0.7-0.7-0.1-0.6-0.4-0.8-1.1
Bone: cortical tissue density0.30.31.1-0.5-0.1-0.6-0.8-0.4-0.6-0.4-1.0-0.0
Condit. Reinf. active minus inactive responses1.11.21.5-1.1-1.1-1.2-1.2-1.1-1.2-1.2-0.9-0.9
Condit. Reinf. active-inactive response ratio0.40.40.7-0.5-0.4-0.8-0.8-0.5-0.7-0.6-0.7-0.4
Condit. Reinf. active responses1.11.42.2-1.5-1.3-1.2-1.1-1.4-1.2-1.3-0.6-0.8
Condit. Reinf. inactive responses0.20.20.5-0.7-0.5-0.10.1-0.7-0.1-0.30.6-0.1
Incentive salience index mean1.51.82.3-1.3-1.5-1.4-1.3-1.5-1.4-1.5-1.1-1.2
Condit. Reinf. lever presses1.21.62.5-1.3-1.6-1.2-1.1-1.5-1.3-1.4-1.0-1.0
Condit. Reinf. active minus inactive responses0.10.20.9-0.20.20.30.30.10.40.40.51.0
Condit. Reinf. active-inactive response ratio0.50.62.4-0.40.20.70.7-0.10.60.40.91.6
Condit. Reinf. active responses0.10.10.2-0.4-0.3-0.3-0.3-0.3-0.3-0.2-0.30.1
Condit. Reinf. inactive responses0.20.31.20.3-0.1-0.5-0.60.1-0.4-0.3-0.7-1.1
Condit. Reinf. lever presses1.11.52.2-1.5-1.5-1.3-1.3-1.4-1.2-1.3-0.7-0.5
Condit. Reinf. lever reinforcers received0.20.30.4-0.7-0.5-0.5-0.6-0.5-0.5-0.4-0.50.0
Conditioned reinforcement - actives0.20.41.3-0.40.30.40.6-0.10.50.41.11.1
Conditioned reinforcement - inactives0.10.20.7-0.8-0.30.10.2-0.70.1-0.20.70.3
Conditioned locomotion1.52.03.01.11.31.71.71.01.61.31.70.8
Patch foraging indifference point 0 sec0.50.91.5-0.8-0.9-0.9-0.9-0.9-1.0-1.0-1.2-0.6
Patch foraging indifference point AUC1.21.83.7-1.9-1.3-1.4-1.5-1.5-1.3-1.3-0.9-0.1
Delay disc. indifference point, 0s delay0.30.30.60.70.30.70.70.40.50.30.3-0.6
Delay disc. indifference point, 16s delay0.20.20.4-0.6-0.6-0.3-0.3-0.6-0.4-0.5-0.2-0.3
Delay disc. indifference point, 2s delay0.10.10.30.20.20.60.50.10.40.20.6-0.1
Delay disc. indifference point, 24s delay0.10.10.50.1-0.2-0.3-0.3-0.1-0.3-0.3-0.5-0.7
Delay disc. indifference point, 4s delay0.40.41.40.0-0.5-0.4-0.4-0.4-0.6-0.6-1.0-1.2
Delay disc. indifference point, 8s delay0.40.41.01.00.80.60.70.80.60.60.10.1
Indifference point function ln k2.74.79.53.12.32.42.22.52.22.01.50.2
Indifference point function log k2.74.79.53.12.32.42.22.52.22.01.50.2
Patch foraging total patch changes 0 sec0.40.81.7-0.5-0.8-1.0-0.9-0.7-0.9-0.9-1.3-0.8
Patch foraging total patch changes 12 sec5.87.58.8-2.9-2.6-2.9-3.0-2.7-2.9-2.7-2.9-1.8
Patch foraging total patch changes 18 sec0.50.71.1-1.1-0.7-0.9-1.0-0.9-0.9-0.8-0.90.0
Patch foraging total patch changes 24 sec5.08.610.0-2.8-3.0-3.0-3.2-2.9-3.1-3.0-3.2-2.0
Patch foraging total patch changes 6 sec1.32.02.9-1.2-1.4-1.4-1.5-1.3-1.5-1.4-1.7-1.3
Patch foraging time to switch 0 sec0.40.71.6-1.2-1.1-0.6-0.5-1.2-0.8-1.0-0.3-0.3
Patch foraging water rate 0 sec0.40.81.61.31.10.80.71.20.91.00.50.3
Patch foraging water rate 12 sec1.63.36.82.61.91.71.72.31.81.91.20.1
Patch foraging water rate 18 sec0.50.82.91.70.70.80.81.20.70.70.2-0.7
Patch foraging water rate 24 sec1.42.03.51.91.61.51.41.71.41.41.00.5
Patch foraging water rate 6 sec1.72.45.32.31.71.51.52.01.51.60.80.4
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.1-0.3-0.2-0.2-0.2-0.2-0.3-0.2-0.7
Distance traveled before self-admin2.43.24.8-2.2-2.0-1.8-1.8-2.1-1.8-1.9-1.4-0.8
Distance traveled after self-admin0.40.50.8-0.8-0.7-0.9-0.9-0.6-0.7-0.6-0.6-0.1
Extensor digitorum longus weight6.525.729.5-4.7-5.4-5.4-5.2-5.0-5.3-5.3-5.2-3.9
Bone: elastic displacement0.60.71.31.21.00.70.61.10.70.90.40.1
Bone: elastic work0.71.02.1-0.3-0.8-1.0-1.1-0.5-1.1-0.9-1.2-1.5
Bone: endosteal estimation0.40.92.60.40.31.41.30.21.10.61.60.5
Bone: endosteal perimeter0.81.74.30.30.51.71.70.31.51.02.11.1
Epididymis fat weight0.41.23.70.20.31.41.30.31.20.81.91.0
Delta time in closed arm before/after self-admin1.00.92.40.0-0.7-0.8-0.8-0.4-1.0-0.9-1.5-1.5
Delta time in open arm before/after self-admin2.32.34.4-2.1-1.6-1.5-1.5-1.8-1.5-1.5-1.0-0.1
Diff in mean of infusions in LGA sessions2.02.53.8-1.4-1.4-1.7-1.7-1.4-1.7-1.6-2.0-1.1
Delay discount exponential model param0.10.10.50.00.30.10.10.30.30.40.50.7
Extinction: sum of active levers before priming4.04.44.8-2.1-2.1-2.2-2.2-2.2-2.2-2.2-2.1-1.5
Active lever presses in extinction session 63.03.04.8-2.2-1.7-1.8-1.8-2.0-1.8-1.8-1.3-0.6
Bone: final force1.93.04.1-1.9-2.0-1.7-1.6-2.0-1.8-1.9-1.4-1.1
Bone: final moment1.93.14.2-1.9-2.0-1.8-1.7-2.0-1.8-1.9-1.5-1.2
Food consumed during 24 hour testing period0.10.10.20.10.00.10.20.20.30.30.50.4
Glucose1.72.64.01.61.42.01.91.41.81.61.80.4
Heart weight0.20.31.00.80.10.60.50.30.30.10.3-1.0
Delay discount hyperbolic model param0.10.10.4-0.00.20.00.00.20.20.30.30.6
Intermittent access intake day 1-15 change1.12.24.00.61.31.51.41.11.61.51.92.0
Intermittent access intake escalation1.42.85.10.71.51.71.61.21.81.72.12.3
Intermittent access intake escalation 20.70.82.4-0.10.60.80.80.30.90.81.31.5
Intermitt. access day 1 inactive lever presses0.41.72.80.71.31.21.41.01.31.31.41.7
Intermitt. access day 15 inactive lever presses0.71.43.1-1.8-1.5-0.9-0.8-1.7-0.9-1.2-0.2-0.4
Intermitt. access escalation Index0.70.91.61.31.11.00.91.21.01.00.70.3
Intermittent access day 1 total infusions0.20.30.8-0.2-0.30.60.8-0.50.4-0.20.9-0.6
Intermittent access day 15 total infusions2.23.27.20.81.42.12.21.02.01.62.71.5
Intermittent access terminal intake (last 3 days)0.60.82.9-0.30.11.11.1-0.30.90.41.70.7
Intermittent access total infusions0.60.72.4-0.00.21.11.2-0.10.90.41.50.3
Intermittent access day 1 locomotion0.10.10.4-0.3-0.40.20.3-0.60.0-0.40.3-0.6
Intermittent access day 15 total locomotion0.20.30.8-0.8-0.30.40.4-0.70.2-0.20.90.3
Intermittent access total locomotion0.40.51.3-1.1-0.60.40.5-1.10.1-0.51.0-0.1
Intermittent access standard deviation0.51.12.20.50.91.11.10.71.11.01.51.2
Left kidney weight0.00.20.7-0.1-0.10.60.6-0.20.40.10.8-0.1
Right kidney weight0.00.10.3-0.2-0.20.40.4-0.20.30.10.60.2
Cocaine induced anxiety0.10.10.3-0.5-0.1-0.1-0.1-0.3-0.1-0.10.10.5
Post-drug Anxiety0.30.30.6-0.8-0.6-0.6-0.6-0.7-0.6-0.6-0.4-0.3
Baseline Anxiety0.50.51.7-0.1-0.6-0.6-0.6-0.3-0.7-0.6-0.9-1.3
Tail length0.20.82.1-0.4-0.7-1.1-1.0-0.4-0.9-0.7-1.5-0.4
Length with tail1.25.37.8-1.9-2.3-2.6-2.5-2.0-2.4-2.3-2.8-1.7
Length without tail2.89.212.0-2.5-3.1-3.2-3.2-2.7-3.2-3.0-3.5-2.7
Times rat made contact with spout0.10.10.50.3-0.0-0.3-0.30.2-0.2-0.1-0.7-0.2
Lifetime Intake0.40.51.60.30.21.01.10.10.80.41.3-0.0
Liver weight, left1.11.82.21.41.41.31.31.51.51.51.30.6
Liver weight, right1.22.13.51.91.41.61.61.61.51.41.2-0.1
Locomotor activity1.01.63.92.01.41.01.11.71.21.30.60.2
Locomotor testing distance1.01.84.52.11.51.21.21.81.21.30.70.0
Locomotor testing rearing0.91.93.92.01.51.41.31.71.31.41.00.1
Locomotion in novel chamber1.51.93.50.91.11.61.61.01.51.31.91.2
Locomotion in novel chamber post-restriction1.72.84.41.11.61.91.71.41.81.71.62.1
Fecal boli incidents, locomotor time 10.20.31.0-0.30.30.40.40.00.50.40.91.0
Change in fecal boli incidents, locomotor task1.21.22.41.61.11.21.21.31.11.00.5-0.0
Time >=10cm from walls, locomotor time 11.31.43.00.30.91.21.50.51.31.11.71.4
Bouts of movement, locomotor time 10.20.21.0-0.30.1-0.6-0.20.1-0.20.1-0.21.0
Total resting periods, locomotor time 10.10.20.8-0.5-0.0-0.5-0.3-0.1-0.20.0-0.10.9
Rest time, locomotor task time 11.72.12.51.21.61.51.21.41.61.61.51.5
Distance moved, locomotor task time 10.30.50.9-0.6-0.7-0.6-0.6-0.7-0.7-0.8-0.5-0.9
Vertical activity count, locomotor time 10.20.40.70.70.70.70.80.60.70.60.60.2
Time >=10cm from walls, locomotor time 20.10.20.8-0.40.2-0.00.1-0.10.20.20.60.9
Bouts of movement, locomotor time 20.71.21.6-1.1-1.1-1.3-1.3-1.0-1.2-1.1-1.0-0.6
Total resting periods, locomotor time 20.30.50.8-0.8-0.8-0.8-0.9-0.7-0.8-0.7-0.6-0.3
Rest time, locomotor task time 22.83.64.31.82.02.12.01.92.12.01.71.5
Distance moved, locomotor task time 20.30.40.8-0.6-0.5-0.9-0.9-0.5-0.7-0.6-0.5-0.3
Vertical activity count, locomotor time 20.10.10.40.60.50.00.10.60.20.4-0.10.0
Light reinforcement 10.00.10.20.30.30.10.10.40.30.30.30.5
Light reinforcement 20.30.41.4-0.8-0.30.30.3-0.50.30.01.01.2
Bone: marrow area0.51.22.90.60.41.61.50.41.20.81.70.5
Bone: maximum diameter0.30.51.5-1.2-1.0-0.5-0.5-1.1-0.5-0.7-0.10.2
Bone: maximum force3.15.68.2-2.7-2.9-2.2-2.2-2.8-2.3-2.6-1.6-1.5
Bone: maximum moment3.25.58.1-2.7-2.8-2.2-2.2-2.8-2.3-2.6-1.6-1.6
Mean time between licks in bursts0.20.62.80.4-0.4-0.7-0.6-0.0-0.6-0.5-0.8-1.7
Mean num. licks in bursts0.10.10.30.50.60.30.10.50.30.40.2-0.3
Cd content in liver0.70.81.90.40.90.90.90.50.90.80.81.4
Co content in liver1.41.63.01.71.71.01.01.71.11.40.50.4
Cu content in liver0.10.10.20.30.30.10.10.30.10.2-0.00.5
Fe content in liver0.10.10.40.20.20.20.10.10.10.1-0.00.7
K content in liver0.60.51.0-0.6-0.9-0.6-0.5-0.7-0.7-0.8-0.6-1.0
Mg content in liver0.10.10.50.1-0.3-0.0-0.0-0.1-0.2-0.3-0.5-0.7
Mn content in liver3.43.84.7-2.2-2.2-2.1-2.0-2.1-2.0-2.0-1.8-0.9
Na content in liver0.50.50.8-0.8-0.9-0.6-0.7-0.8-0.7-0.8-0.5-0.7
Rb content in liver2.83.24.52.11.81.92.02.01.81.81.41.0
Se content in liver0.30.30.8-0.9-0.6-0.3-0.3-0.7-0.3-0.40.00.9
Sr content in liver4.13.54.2-2.0-1.8-2.0-2.0-1.9-2.0-1.9-2.1-1.0
Zn content in liver2.83.24.3-1.7-1.7-1.8-1.8-1.8-1.9-1.8-2.1-1.4
Bone: minimum diameter0.20.41.4-0.1-0.20.80.9-0.20.60.21.2-0.0
Time in familiar zone, hab. session 10.20.20.8-0.2-0.4-0.3-0.4-0.4-0.3-0.4-0.1-0.9
Time in novel zone, hab. session 11.61.62.21.51.41.31.31.51.31.31.00.8
Total zone transitions, hab. session 10.20.31.0-0.4-0.3-0.5-0.4-0.4-0.5-0.5-1.0-0.6
Total locomotion distance, hab. session 10.00.00.1-0.2-0.10.30.3-0.20.1-0.0-0.1-0.3
Locomotion velocity, hab. session 10.20.30.5-0.7-0.5-0.3-0.2-0.7-0.4-0.5-0.7-0.5
Time in familiar zone, hab. session 20.50.51.21.10.70.40.31.00.60.80.7-0.4
Time in novel zone, hab. session 20.60.61.0-0.9-0.9-0.6-0.6-1.0-0.8-0.9-0.8-0.2
Total zone transitions, hab. session 21.51.93.7-0.9-1.3-1.3-1.2-1.2-1.4-1.4-1.6-1.9
Total locomotion distance, hab. session 20.30.41.4-0.3-0.5-0.3-0.2-0.5-0.5-0.6-0.7-1.2
Locomotion velocity, hab. session 20.20.20.9-0.3-0.4-0.1-0.0-0.5-0.3-0.5-0.5-0.9
Novel to familiar place preference ratio2.12.33.5-1.9-1.7-1.6-1.4-1.8-1.6-1.6-1.2-0.4
Novelty place preference1.31.42.4-1.5-1.3-1.3-1.1-1.4-1.2-1.3-0.9-0.2
Time in novel zone, NPP test1.41.52.3-1.5-1.4-1.3-1.1-1.4-1.3-1.3-0.9-0.4
Total zone transitions, NPP test1.01.42.9-0.9-1.0-1.1-1.1-1.1-1.3-1.3-1.7-1.1
Total locomotion distance, NPP test0.10.10.4-0.0-0.1-0.00.0-0.3-0.3-0.3-0.7-0.4
Locomotion velocity, NPP test0.00.00.30.00.10.10.1-0.1-0.2-0.2-0.6-0.1
Intraocular pressure0.30.42.00.30.50.30.30.50.50.60.51.4
Delta distance traveled before/after self-admin0.70.71.81.31.00.60.61.20.70.90.3-0.1
Delta ambulatory time before/after self-admin1.01.22.51.61.30.90.91.51.01.20.50.2
Parametrial fat weight0.81.94.40.60.91.71.70.71.71.22.11.0
Pavlov. Cond. lever latency1.21.52.21.31.51.21.11.41.21.30.91.1
Pavlov. Cond. magazine entry latency1.52.03.1-1.7-1.7-1.3-1.3-1.7-1.3-1.4-0.5-1.3
Pavlov. Cond. change in total contacts0.70.71.9-1.4-1.0-0.7-0.7-1.2-0.7-0.8-0.2-0.2
Pavlov. Cond. index score0.91.21.8-1.3-1.3-1.1-1.1-1.3-1.0-1.1-0.5-0.8
Pavlov. Cond. latency score0.81.01.5-1.2-1.2-1.0-1.0-1.2-1.0-1.1-0.5-1.0
Pavlov. Cond. lever contacts0.70.81.3-0.9-1.1-0.8-0.8-1.0-0.8-1.0-0.5-1.1
Pavlov. Cond. magazine entry number0.91.22.11.51.21.21.21.31.11.10.50.5
Pavlov. Cond. intertrial magazine entries0.10.21.0-0.50.1-0.2-0.1-0.2-0.10.00.31.0
Pavlov. Cond. lever-magazine prob. diff.1.01.32.2-1.5-1.3-1.1-1.1-1.4-1.1-1.1-0.5-0.8
Pavlov. Cond. response bias1.21.52.4-1.6-1.4-1.2-1.2-1.4-1.2-1.2-0.6-0.8
Pavlov. Cond. lever latency0.70.91.41.11.21.01.11.10.91.00.40.5
Pavlov. Cond. magazine entry latency5.26.27.5-2.7-2.6-2.7-2.7-2.6-2.6-2.6-1.9-1.9
Pavlov. Cond. change in total contacts1.62.54.2-2.0-1.8-1.6-1.8-1.8-1.5-1.6-0.7-0.8
Pavlov. Cond. index score3.04.15.7-2.4-2.3-2.1-2.2-2.3-2.1-2.1-1.1-1.2
Pavlov. Cond. latency score2.83.85.6-2.4-2.2-2.0-2.1-2.2-2.0-2.0-1.1-1.1
Pavlov. Cond. lever contacts0.60.81.1-1.0-1.0-0.9-1.0-1.0-0.8-0.9-0.2-0.5
Pavlov. Cond. magazine entry number7.89.611.83.43.23.33.43.33.33.22.42.0
Pavlov. Cond. intertrial magazine entries1.62.43.31.31.61.61.51.51.61.61.21.8
Pavlov. Cond. lever-magazine prob. diff.3.44.66.3-2.5-2.4-2.2-2.4-2.4-2.2-2.2-1.2-1.3
Pavlov. Cond. response bias2.33.13.9-1.9-2.0-1.9-2.0-1.9-1.8-1.8-1.1-1.4
Time in closed arm before self-admin0.10.10.4-0.5-0.20.10.1-0.30.20.00.60.4
Time in closed arm after self-admin0.90.91.41.20.91.01.01.11.01.00.90.2
Time in open arm before self-admin1.51.74.82.21.41.11.11.71.01.20.1-0.3
Time in open arm after self-admin0.40.41.1-0.3-0.4-0.7-0.7-0.4-0.7-0.6-1.1-0.3
Bone: periosteal estimation0.20.30.9-0.9-0.9-0.0-0.0-1.0-0.2-0.60.4-0.2
Bone: periosteal perimeter0.10.20.7-0.9-0.7-0.1-0.1-0.8-0.1-0.40.30.0
Bone: post-yield work0.30.51.4-1.1-0.90.1-0.0-1.2-0.1-0.60.70.0
Progressive ratio test 1 active lever presses0.20.30.60.20.50.60.80.20.60.40.80.4
Progressive ratio test 1 breakpoint0.20.30.70.20.50.60.80.20.60.40.80.5
Progressive ratio test 1 inactive lever presses0.60.81.3-1.1-1.1-0.9-0.7-1.1-0.9-1.0-0.6-0.7
Progressive ratio test 2 active lever presses0.60.72.1-0.10.50.91.00.10.90.51.40.8
Progressive ratio test 2 breakpoint0.50.61.9-0.10.40.90.9-0.00.80.51.40.8
Progressive ratio test 2 inactive lever presses0.30.51.7-0.40.10.70.8-0.20.60.31.30.6
Incentive Sensitization - Responses0.81.22.4-1.5-1.3-0.8-0.9-1.5-0.9-1.2-0.3-0.5
Incentive Sensitization - Breakpoint0.70.92.1-1.4-1.2-0.7-0.8-1.4-0.8-1.0-0.2-0.4
Sum of active levers in priming session hrs 5-61.11.02.9-1.7-0.8-1.1-1.1-1.1-0.9-0.7-0.30.8
Progressive ratio0.10.20.5-0.5-0.7-0.1-0.0-0.6-0.1-0.30.3-0.2
Food seeking constrained by brief footshock0.10.10.20.40.10.20.30.30.20.20.0-0.4
Seeking ratio, punishment vs. effort0.20.30.80.90.70.30.20.70.20.3-0.4-0.5
Retroperitoneal fat weight3.012.917.63.43.24.24.23.24.03.64.02.2
Reaction time number correct0.20.40.9-0.3-0.7-0.9-0.9-0.4-0.7-0.7-0.7-0.5
Reaction time mean minus median0.30.72.2-1.5-0.7-0.8-0.9-1.0-0.6-0.6-0.20.4
Reaction time mean minus median AUC0.10.10.4-0.6-0.0-0.4-0.5-0.2-0.2-0.00.00.5
Reaction time num false alarms0.50.72.21.51.20.70.51.20.60.80.0-0.4
Reaction time num false alarms AUC0.20.41.21.10.80.1-0.10.80.10.3-0.6-0.5
Reaction time trials correct on left0.20.40.9-0.3-0.7-0.9-0.9-0.4-0.7-0.7-0.7-0.5
Reaction time trials on left0.20.50.9-0.3-0.7-0.9-0.9-0.4-0.8-0.7-0.7-0.5
Reaction time mean0.10.10.3-0.40.30.2-0.1-0.10.20.20.60.4
Reaction time mean AUC0.10.20.6-0.30.30.20.10.10.30.40.80.5
Median of all reaction times0.00.00.2-0.30.20.2-0.1-0.10.10.10.40.1
Reaction time omissions0.20.20.6-0.6-0.2-0.5-0.8-0.4-0.5-0.3-0.5-0.1
Reaction time false alarm rate0.40.51.31.11.00.70.50.90.50.6-0.0-0.3
Reaction time premature initiation rate4.36.08.3-1.6-2.6-2.5-2.5-2.1-2.6-2.5-2.7-2.9
Reaction time premature initiations3.86.88.7-1.6-2.7-2.9-2.9-2.1-2.8-2.7-2.9-2.7
Std. dev. reaction times0.10.21.0-0.40.50.2-0.10.10.30.40.51.0
Reaction time trials completed0.20.50.9-0.3-0.7-0.9-0.9-0.4-0.8-0.7-0.7-0.5
Reaction time trials AUC0.20.40.7-0.2-0.6-0.8-0.8-0.3-0.7-0.6-0.6-0.5
Run reversals in cocaine runway, females0.80.83.10.0-0.8-0.6-0.5-0.5-0.7-0.9-1.1-1.8
Run reversals in cocaine runway, males0.60.60.80.80.90.70.80.90.80.80.30.6
Latency to leave start box in cocaine runway0.20.20.60.30.30.60.60.20.60.40.80.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.2-0.3-0.2-0.2-0.3-0.2-0.3-0.1-0.4
Latency to leave start box in cocaine runway, M1.81.72.31.21.21.51.51.11.41.31.50.9
Std. dev. time between licks in bursts0.30.41.11.00.40.20.30.70.30.30.1-1.0
Total sessions with >9 infusions0.60.71.10.70.61.01.00.60.90.71.10.3
Short access day 1 total inactive lever presses0.00.10.30.0-0.10.10.1-0.20.0-0.20.1-0.6
Short access day 10 total inactive lever presses0.30.70.90.91.00.80.81.00.90.90.70.7
Short access day 1 total infusions0.91.21.81.10.91.41.30.91.21.01.30.2
Short access day 10 total infusions0.10.20.5-0.1-0.20.50.6-0.30.3-0.10.7-0.5
Short access total infusions0.30.40.90.70.30.91.00.30.70.40.8-0.5
Short access day 1 locomotion0.10.20.40.10.20.60.60.10.40.20.70.2
Short access day 10 total locomotion0.20.30.8-0.8-0.7-0.1-0.1-0.9-0.3-0.6-0.0-0.4
Short access total locomotion0.10.10.2-0.3-0.20.30.4-0.40.2-0.10.5-0.1
One hour access (0.3 mA shock)0.60.71.80.20.41.21.10.21.00.61.40.6
Compulsive drug intake0.50.61.70.1-0.5-0.9-1.1-0.0-0.8-0.5-1.3-0.8
One hour access (shock baseline)1.92.96.00.61.32.12.20.81.91.52.51.6
Social response proportion0.00.00.10.0-0.3-0.2-0.1-0.0-0.1-0.10.0-0.2
Social responses0.00.00.10.30.0-0.2-0.20.3-0.10.1-0.20.1
Social time0.10.10.40.60.40.20.10.60.20.4-0.30.2
Soleus weight2.88.410.03.03.03.03.23.03.13.02.81.9
Bone: stiffness0.91.52.9-1.7-1.5-1.2-1.0-1.5-1.1-1.2-0.5-0.4
Tibialis anterior weight8.729.734.1-5.4-5.5-5.8-5.8-5.4-5.8-5.6-5.8-3.4
Time to tail flick, vehicle, before self-admin0.30.30.7-0.8-0.7-0.3-0.4-0.9-0.5-0.7-0.2-0.4
Time to tail flick, vehicle, after self-admin0.40.51.3-0.4-0.8-0.5-0.5-0.6-0.6-0.7-0.7-1.1
Time to tail flick, test, before self-admin0.60.61.8-0.3-0.9-0.5-0.5-0.8-0.7-0.9-0.9-1.3
Time to tail flick, test, after self-admin0.10.10.2-0.5-0.3-0.2-0.2-0.3-0.1-0.20.10.4
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.1-0.4-0.4-0.3-0.2-0.4-0.4-0.7-0.7
Delta time to tail flick, test, before/after SA0.30.31.9-0.30.3-0.1-0.10.20.20.40.51.4
Tibia length1.74.69.0-3.0-2.3-2.2-2.0-2.7-2.1-2.2-1.7-0.2
Ambulatory time before self-admin1.82.74.7-2.2-1.9-1.6-1.6-2.0-1.6-1.7-1.1-0.5
Ambulatory time after self-admin0.20.20.5-0.7-0.6-0.6-0.5-0.6-0.4-0.4-0.2-0.1
Bone: tissue strength0.40.40.70.80.40.50.60.80.60.60.60.8
Total heroin consumption4.95.77.4-2.4-2.2-2.7-2.7-2.2-2.6-2.4-2.7-1.0
Bone: trabecular number1.32.13.1-1.6-1.8-1.4-1.4-1.8-1.5-1.7-1.2-0.5
Bone: trabecular spacing0.91.22.01.41.20.90.91.41.01.20.80.4
Bone: trabecular thickness0.10.10.4-0.10.20.30.3-0.00.30.20.60.0
Bone: trabecular tissue density5.88.510.72.83.33.02.93.03.03.12.52.8
Water consumed over 24 hours0.40.61.0-0.4-0.8-1.0-0.9-0.4-0.8-0.7-1.0-0.6
Number of responses in last shaping day0.10.10.30.1-0.2-0.3-0.3-0.1-0.4-0.3-0.6-0.5