Hub : Genes

LOC134483845

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC134483845 0.51 0.12 0.0e+00 0.55 0.54 0.56 0.56 1.3e-73 8.7e-72 2.5e-74 1.4e-75
2 LHb gene expression LOC134483845 0.37 0.15 1.1e-07 0.2 0.21 0.24 0.23 1.5e-05 1.0e-05 2.1e-06 3.5e-06
3 OFC gene expression LOC134483845 0.17 0.11 4.5e-03 0.08 0.06 0.05 0.06 5.0e-03 1.6e-02 2.3e-02 1.4e-02
4 BLA gene expression LOC134483845 0.16 0.09 5.8e-08 0.08 0.11 0.11 0.11 4.4e-05 1.7e-06 1.2e-06 2.4e-06
5 RMTg gene expression LOC134483845 0.42 0.17 1.5e-08 0.23 0.21 0.26 0.1 9.3e-07 3.2e-06 1.9e-07 1.7e-03
6 Brain gene expression LOC134483845 0.5 0.12 0.0e+00 0.29 0.31 0.31 0.31 3.7e-27 2.0e-29 2.3e-29 1.3e-29
7 pVTA gene expression LOC134483845 0.38 0.11 0.0e+00 0.44 0.24 0.43 0.17 1.2e-38 1.1e-19 1.8e-37 5.9e-14
8 NAcc gene expression LOC134483845 0.25 0.1 0.0e+00 0.31 0.3 0.3 0.3 4.2e-47 6.6e-47 8.2e-47 8.4e-47
9 PL gene expression LOC134483845 0.28 0.15 0.0e+00 0.24 0.23 0.24 0.25 5.1e-26 5.4e-25 3.6e-26 1.0e-26
10 IC gene expression LOC134483845 0.32 0.12 1.8e-12 0.24 0.21 0.23 0.22 1.6e-10 2.3e-09 5.2e-10 1.4e-09
11 Adipose gene expression LOC134483845 0.05 0.04 2.8e-05 0.04 0.04 0.04 0.04 8.6e-06 2.5e-05 1.9e-05 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.51.02.71.7-1.2-0.8-1.2-0.80.4-0.9-0.90.7-0.9-0.9
Area under the delay curve1.52.34.1-1.61.61.51.71.1-0.81.61.7-1.51.12.0
BMI with tail1.96.69.1-2.02.42.62.62.7-3.02.62.6-2.72.52.4
BMI without tail2.412.515.3-3.43.73.63.53.9-3.83.53.6-3.53.23.2
Body weight5.624.536.0-5.95.34.75.16.0-4.34.84.9-4.24.64.3
Weight adjusted by age0.92.54.0-2.01.51.91.91.9-0.91.61.6-1.31.31.2
Bone surface0.00.00.2-0.50.20.2-0.10.40.00.00.10.00.1-0.2
Bone volume0.10.20.6-0.30.30.50.20.8-0.60.40.4-0.40.40.1
Breakpoint value in progressive ratio session0.30.51.00.6-0.3-0.6-0.7-0.90.2-0.8-0.80.8-1.0-0.9
Number of licking bursts0.31.02.80.4-0.8-1.0-0.8-1.71.4-1.0-1.00.9-1.0-0.8
Context. condit. distance diff. score9.211.113.32.6-3.3-3.4-3.6-3.03.3-3.4-3.43.6-3.5-3.5
Locomotion velocity, session 10.60.70.90.6-0.8-0.9-0.8-0.70.9-0.8-0.91.0-0.8-0.9
Locomotion distance, session 10.10.10.70.8-0.30.0-0.1-0.5-0.1-0.00.00.0-0.10.1
Locomotion velocity, session 20.10.10.10.0-0.2-0.4-0.1-0.20.4-0.3-0.30.3-0.3-0.1
Locomotion distance, session 20.20.20.50.7-0.6-0.4-0.4-0.60.5-0.4-0.40.5-0.5-0.3
Locomotion velocity, session 30.20.20.6-0.00.40.60.30.5-0.80.50.6-0.40.60.1
Locomotion distance, session 30.91.01.71.3-1.1-0.9-1.3-0.70.7-0.9-0.91.0-1.0-1.1
Stereotopy head waving bouts, day 30.50.62.5-1.61.00.70.90.7-0.30.70.7-0.40.70.3
Stereotopy head waving duration, day 30.50.61.9-1.40.90.81.00.6-0.40.70.7-0.50.70.5
Locomotion velocity, session 74.65.06.32.4-2.5-2.3-2.5-1.91.8-2.3-2.22.2-2.2-2.2
Locomotion distance, session 72.93.75.82.4-2.2-1.9-2.2-1.71.4-1.9-1.91.7-1.9-1.7
Stereotopy head waving bouts, day 72.22.64.4-2.11.81.61.71.6-1.41.61.5-1.41.71.0
Stereotopy head waving duration, day 72.22.84.6-2.11.81.71.81.7-1.51.61.6-1.51.71.2
Locomotion velocity, session 81.51.83.8-0.2-0.9-1.4-1.1-1.12.0-1.4-1.31.7-1.5-1.3
Locomotion distance, session 84.97.18.52.2-2.7-2.7-2.9-2.32.7-2.7-2.72.9-2.8-2.7
Degree of sensitization distance0.80.91.40.5-0.9-1.0-0.8-1.11.2-1.0-1.00.9-0.9-0.7
Degree of sensitization stereotypy1.11.21.7-1.31.21.11.11.0-1.11.11.1-1.01.20.6
Conditioned locomotion0.40.50.9-1.00.70.60.90.6-0.30.50.5-0.50.51.0
Cocaine response after cond. corrected0.30.51.00.9-0.7-0.6-0.7-1.00.5-0.6-0.70.6-0.7-0.5
Cocaine response after cond. not corrected0.00.00.1-0.20.0-0.2-0.0-0.20.3-0.1-0.20.3-0.3-0.0
Cocaine response before conditioning2.63.17.3-2.72.01.52.02.1-1.11.51.5-1.41.61.5
Saline control response2.94.05.6-1.31.82.01.92.4-2.22.01.9-2.22.12.1
Bone: connectivity density2.13.34.72.2-2.0-1.7-2.0-1.71.5-1.8-1.71.7-1.8-1.7
Bone: cortical apparent density0.81.21.7-0.30.91.11.11.0-1.31.11.1-1.31.11.3
Bone: cortical area1.42.33.2-1.81.61.51.61.7-1.31.51.5-1.31.51.3
Bone: cortical porosity0.70.81.0-1.00.90.90.90.7-0.70.90.9-0.90.80.9
Bone: cortical porosity0.30.30.9-1.00.70.60.60.4-0.20.50.6-0.50.50.6
Bone: cortical thickness4.88.19.1-2.02.73.02.92.8-3.02.93.0-2.93.02.7
Bone: cortical thickness2.12.63.9-0.71.31.71.61.6-2.01.71.7-1.81.71.7
Bone: cortical tissue density0.60.91.4-0.30.81.01.00.9-1.21.01.0-1.21.01.1
Condit. Reinf. active minus inactive responses0.80.91.31.1-1.0-0.9-1.0-1.01.0-0.9-0.91.0-0.9-0.8
Condit. Reinf. active-inactive response ratio0.10.10.30.10.20.20.40.1-0.30.30.2-0.50.40.6
Condit. Reinf. active responses1.21.62.51.6-1.3-1.2-1.4-1.11.1-1.1-1.21.2-1.1-1.2
Condit. Reinf. inactive responses1.31.73.71.9-1.5-1.1-1.6-1.10.9-1.2-1.11.2-1.2-1.3
Incentive salience index mean2.33.03.81.5-1.7-1.8-1.8-1.62.0-1.7-1.81.9-1.7-1.6
Condit. Reinf. lever presses4.46.67.92.0-2.5-2.6-2.7-2.22.8-2.6-2.62.8-2.6-2.6
Condit. Reinf. active minus inactive responses0.60.81.8-1.31.00.81.10.6-0.30.80.8-0.80.91.2
Condit. Reinf. active-inactive response ratio0.91.43.6-1.91.41.01.50.8-0.51.11.0-1.01.11.3
Condit. Reinf. active responses0.10.10.40.1-0.3-0.2-0.2-0.40.6-0.3-0.20.3-0.2-0.1
Condit. Reinf. inactive responses1.11.62.61.6-1.5-1.1-1.5-1.11.0-1.2-1.11.1-1.2-1.2
Condit. Reinf. lever presses0.81.21.71.0-1.1-1.0-1.2-1.31.1-1.0-1.01.1-1.0-1.2
Condit. Reinf. lever reinforcers received0.20.20.70.3-0.5-0.4-0.4-0.70.8-0.5-0.40.5-0.4-0.3
Conditioned reinforcement - actives0.52.14.1-1.31.72.01.31.1-1.61.51.4-1.51.21.2
Conditioned reinforcement - inactives0.82.23.3-1.41.51.81.51.0-1.51.71.6-1.51.31.4
Conditioned locomotion0.10.10.3-0.50.50.60.3-0.0-0.20.20.2-0.50.40.3
Patch foraging indifference point 0 sec0.51.32.7-0.61.11.60.90.8-1.51.31.4-1.10.90.6
Patch foraging indifference point AUC0.51.31.8-1.31.10.71.21.3-0.71.21.1-1.21.31.2
Delay disc. indifference point, 0s delay0.30.40.9-0.90.50.80.60.50.00.60.6-0.40.40.9
Delay disc. indifference point, 16s delay2.33.24.5-1.31.92.01.91.2-1.71.91.9-1.91.62.1
Delay disc. indifference point, 2s delay1.51.72.9-1.71.41.41.60.7-0.61.31.4-1.20.91.7
Delay disc. indifference point, 24s delay0.40.70.9-0.70.90.80.80.3-0.80.90.9-0.90.70.9
Delay disc. indifference point, 4s delay2.52.74.8-2.01.81.61.91.6-0.71.51.5-1.51.22.2
Delay disc. indifference point, 8s delay0.30.61.3-0.70.60.70.80.4-0.20.91.0-0.70.51.1
Indifference point function ln k0.30.81.80.4-0.7-0.7-1.0-0.91.1-0.9-0.81.0-0.7-1.3
Indifference point function log k0.30.81.80.4-0.7-0.7-1.0-0.91.1-0.9-0.81.0-0.7-1.3
Patch foraging total patch changes 0 sec0.61.93.5-0.81.41.91.11.0-1.81.61.7-1.31.20.8
Patch foraging total patch changes 12 sec1.62.23.1-0.81.31.61.41.2-1.61.81.7-1.61.31.6
Patch foraging total patch changes 18 sec0.41.02.2-0.10.71.00.60.9-1.51.31.3-1.11.10.7
Patch foraging total patch changes 24 sec0.10.31.30.70.10.50.10.1-1.10.60.5-0.70.30.3
Patch foraging total patch changes 6 sec1.32.33.5-0.71.31.61.51.2-1.91.71.7-1.81.31.6
Patch foraging time to switch 0 sec0.00.10.40.6-0.20.10.00.0-0.40.00.1-0.2-0.00.3
Patch foraging water rate 0 sec0.20.91.2-1.00.90.81.10.6-0.81.00.9-1.01.01.0
Patch foraging water rate 12 sec0.00.10.20.30.10.30.30.1-0.30.30.2-0.50.30.3
Patch foraging water rate 18 sec0.10.20.5-0.70.50.20.40.6-0.30.40.2-0.30.40.1
Patch foraging water rate 24 sec1.52.23.9-1.61.51.21.52.0-1.41.51.4-1.51.71.0
Patch foraging water rate 6 sec0.10.20.5-0.10.30.30.40.4-0.50.60.5-0.70.60.5
Seeking ratio, delayed vs. immediate footshock0.30.50.8-0.80.70.70.80.8-0.60.40.2-0.60.40.9
Distance traveled before self-admin0.00.10.2-0.3-0.10.1-0.20.40.4-0.1-0.20.5-0.2-0.4
Distance traveled after self-admin0.30.61.2-1.11.10.90.71.0-0.70.60.5-0.30.50.1
Extensor digitorum longus weight0.10.21.0-0.1-0.2-0.2-0.60.00.3-0.4-0.40.6-0.4-1.0
Bone: elastic displacement0.60.71.0-0.50.80.80.90.7-1.00.80.8-1.00.81.0
Bone: elastic work2.53.34.0-1.82.01.92.01.7-1.71.81.8-1.81.81.7
Bone: endosteal estimation0.20.64.7-2.20.80.00.40.80.70.00.00.3-0.0-0.1
Bone: endosteal perimeter0.92.24.1-0.3-1.0-1.6-1.4-0.92.0-1.6-1.61.8-1.6-1.7
Epididymis fat weight3.216.025.9-1.43.44.13.93.1-5.14.24.3-4.74.14.6
Delta time in closed arm before/after self-admin0.50.50.8-0.90.50.60.90.5-0.40.70.8-0.80.70.8
Delta time in open arm before/after self-admin0.20.20.6-0.40.80.70.20.7-0.60.30.4-0.10.40.3
Diff in mean of infusions in LGA sessions2.13.77.62.5-1.9-1.5-2.2-2.81.5-1.8-1.71.7-1.8-1.6
Delay discount exponential model param1.72.34.21.6-1.6-1.5-1.7-1.10.8-1.6-1.71.5-1.1-2.0
Extinction: sum of active levers before priming0.60.82.30.6-0.5-0.7-0.7-1.50.7-0.9-0.90.8-1.0-1.2
Active lever presses in extinction session 60.10.10.40.40.00.60.2-0.1-0.60.10.1-0.3-0.10.4
Bone: final force6.410.411.3-3.13.33.43.33.3-3.23.33.4-3.13.32.8
Bone: final moment5.79.210.3-3.03.13.13.13.2-3.03.13.1-2.93.02.6
Food consumed during 24 hour testing period0.20.31.7-1.00.50.20.41.3-0.10.20.2-0.20.30.2
Glucose3.35.29.70.8-2.0-2.4-2.2-1.83.1-2.4-2.52.6-2.4-2.2
Heart weight1.82.83.8-1.61.91.81.90.9-1.51.61.7-1.81.91.6
Delay discount hyperbolic model param1.92.54.41.7-1.6-1.5-1.8-1.20.8-1.7-1.81.5-1.2-2.1
Intermittent access intake day 1-15 change0.00.10.30.5-0.6-0.1-0.1-0.20.2-0.4-0.40.00.0-0.1
Intermittent access intake escalation0.00.10.40.1-0.10.40.40.5-0.40.20.1-0.50.40.6
Intermittent access intake escalation 20.10.20.60.2-0.8-0.3-0.20.10.5-0.4-0.40.4-0.2-0.2
Intermitt. access day 1 inactive lever presses0.00.10.4-0.5-0.0-0.20.1-0.60.4-0.1-0.10.2-0.0-0.6
Intermitt. access day 15 inactive lever presses0.21.01.6-1.31.01.00.91.3-0.91.11.1-0.81.00.4
Intermitt. access escalation Index1.23.74.71.9-1.9-2.2-2.0-2.01.8-2.1-2.11.8-2.0-1.4
Intermittent access day 1 total infusions0.10.20.50.20.70.5-0.1-0.5-0.70.30.3-0.2-0.20.3
Intermittent access day 15 total infusions0.20.51.0-0.10.80.90.50.3-1.00.50.6-0.70.31.0
Intermittent access terminal intake (last 3 days)0.61.01.8-0.51.11.30.90.4-1.30.91.0-1.00.71.1
Intermittent access total infusions0.50.61.2-0.41.01.10.60.3-1.10.80.8-0.70.50.9
Intermittent access day 1 locomotion0.00.10.30.00.4-0.2-0.2-0.1-0.2-0.2-0.30.0-0.50.4
Intermittent access day 15 total locomotion0.41.52.4-1.41.41.21.31.1-1.11.11.1-1.20.81.6
Intermittent access total locomotion1.11.32.2-1.31.51.21.11.1-1.01.01.0-1.10.71.4
Intermittent access standard deviation0.73.85.3-1.51.92.32.11.8-2.11.81.8-2.02.11.8
Left kidney weight2.621.129.4-4.94.94.54.75.4-4.54.34.3-4.24.64.0
Right kidney weight3.222.131.7-5.25.04.64.95.6-4.24.34.5-4.34.54.5
Cocaine induced anxiety0.51.31.80.7-1.1-1.3-1.3-0.91.3-1.1-1.11.3-1.1-1.2
Post-drug Anxiety0.70.81.20.7-1.1-0.8-1.0-0.61.1-0.8-0.71.1-0.9-0.9
Baseline Anxiety0.10.10.60.7-0.40.3-0.1-0.80.2-0.1-0.10.1-0.20.0
Tail length1.58.220.8-4.63.42.52.93.7-1.62.62.6-1.92.32.1
Length with tail2.812.631.1-5.64.13.13.64.8-2.03.13.2-2.33.02.6
Length without tail1.99.919.6-4.43.52.93.43.9-2.12.92.9-2.33.02.5
Times rat made contact with spout0.20.31.71.3-0.6-0.2-0.5-0.3-0.4-0.3-0.20.0-0.2-0.2
Lifetime Intake0.91.12.1-0.81.31.50.80.5-1.31.11.1-0.90.61.2
Liver weight, left0.20.30.9-1.00.2-0.4-0.10.60.7-0.6-0.60.6-0.6-0.3
Liver weight, right0.71.25.3-2.31.40.91.11.50.00.50.5-0.40.30.8
Locomotor activity0.20.31.5-1.2-0.2-0.40.10.90.8-0.3-0.30.5-0.1-0.3
Locomotor testing distance0.10.30.9-0.5-0.5-0.6-0.40.10.9-0.4-0.50.7-0.3-0.7
Locomotor testing rearing0.00.20.9-0.90.3-0.20.10.80.30.00.00.20.10.1
Locomotion in novel chamber0.60.92.0-1.01.01.10.71.4-0.91.00.8-0.60.80.6
Locomotion in novel chamber post-restriction0.61.73.0-1.11.01.71.61.3-1.01.21.3-1.21.11.5
Fecal boli incidents, locomotor time 10.20.71.11.1-0.5-0.9-1.1-1.00.2-0.6-0.60.8-0.6-1.0
Change in fecal boli incidents, locomotor task0.40.40.9-0.90.70.60.9-0.2-0.40.60.6-0.60.70.6
Time >=10cm from walls, locomotor time 10.10.10.6-0.80.50.00.30.2-0.20.20.20.0-0.1-0.2
Bouts of movement, locomotor time 10.91.12.01.0-1.2-0.9-1.2-0.41.4-1.1-1.11.3-0.9-0.6
Total resting periods, locomotor time 10.50.61.10.7-0.8-0.5-0.8-0.41.1-0.8-0.81.1-0.7-0.4
Rest time, locomotor task time 10.00.10.1-0.3-0.3-0.10.20.30.2-0.2-0.20.3-0.30.2
Distance moved, locomotor task time 10.30.81.5-0.71.01.20.80.7-1.00.80.8-1.11.00.3
Vertical activity count, locomotor time 10.10.40.8-0.50.60.60.60.6-0.70.60.6-0.80.90.1
Time >=10cm from walls, locomotor time 20.00.10.4-0.30.1-0.40.0-0.60.2-0.3-0.30.1-0.0-0.1
Bouts of movement, locomotor time 20.10.31.7-0.8-0.2-0.40.31.30.4-0.1-0.10.2-0.00.3
Total resting periods, locomotor time 20.10.41.1-0.6-0.6-0.8-0.11.00.8-0.4-0.40.6-0.4-0.1
Rest time, locomotor task time 21.11.82.80.4-1.3-1.5-1.2-0.61.5-1.6-1.61.7-1.4-1.4
Distance moved, locomotor task time 21.72.33.3-0.91.51.81.51.1-1.51.51.5-1.81.61.5
Vertical activity count, locomotor time 20.10.30.6-0.10.30.50.7-0.3-0.30.50.5-0.70.40.8
Light reinforcement 10.10.20.5-0.20.40.70.4-0.1-0.40.70.7-0.50.60.3
Light reinforcement 20.20.41.0-1.00.70.60.70.7-0.30.60.5-0.50.50.6
Bone: marrow area0.30.64.7-2.20.80.00.50.80.60.10.00.30.0-0.1
Bone: maximum diameter0.20.30.7-0.90.0-0.5-0.4-0.10.8-0.4-0.50.7-0.5-0.8
Bone: maximum force4.28.39.4-2.93.03.03.03.1-2.72.82.9-2.82.82.7
Bone: maximum moment3.77.18.8-2.82.82.72.73.0-2.52.62.6-2.52.62.5
Mean time between licks in bursts0.31.72.90.1-1.0-1.5-1.2-0.71.7-1.4-1.51.5-1.5-1.3
Mean num. licks in bursts0.30.82.30.30.40.80.41.4-1.50.80.8-0.90.80.7
Cd content in liver0.10.10.60.10.00.10.40.1-0.40.10.1-0.4-0.10.8
Co content in liver1.51.72.5-0.81.21.31.50.9-1.51.31.3-1.61.41.5
Cu content in liver0.60.72.81.7-1.1-0.7-1.0-0.90.4-0.6-0.60.3-0.7-0.3
Fe content in liver1.21.52.1-0.71.11.21.31.3-1.41.21.2-1.41.21.5
K content in liver0.10.10.30.5-0.4-0.3-0.4-0.20.1-0.1-0.10.10.2-0.6
Mg content in liver1.61.82.41.0-1.3-1.4-1.5-1.41.5-1.3-1.21.3-1.2-1.4
Mn content in liver4.75.38.01.4-2.2-2.4-2.4-2.12.8-2.3-2.32.5-2.2-2.4
Na content in liver0.80.91.8-0.30.80.91.00.6-0.80.90.9-1.31.21.2
Rb content in liver0.91.01.51.1-1.1-1.1-1.2-1.01.1-0.9-1.00.8-0.9-0.7
Se content in liver1.31.53.80.4-1.1-1.5-0.9-1.02.0-1.4-1.41.2-1.3-0.6
Sr content in liver0.20.20.6-0.80.50.40.50.4-0.10.40.3-0.30.40.2
Zn content in liver0.10.10.20.1-0.3-0.4-0.4-0.10.4-0.4-0.30.4-0.4-0.5
Bone: minimum diameter0.20.41.1-1.0-0.1-0.5-0.3-0.01.1-0.6-0.60.8-0.5-0.8
Time in familiar zone, hab. session 10.80.93.31.8-1.1-0.8-0.9-1.00.3-0.9-0.90.5-0.7-0.4
Time in novel zone, hab. session 10.30.31.8-1.30.70.40.50.7-0.00.40.5-0.10.30.1
Total zone transitions, hab. session 10.60.91.41.1-1.0-0.8-1.1-1.20.7-0.8-0.71.0-0.8-1.2
Total locomotion distance, hab. session 10.40.51.20.9-0.7-0.5-0.8-1.00.4-0.5-0.40.8-0.5-1.1
Locomotion velocity, hab. session 10.10.20.50.5-0.3-0.1-0.4-0.70.0-0.1-0.10.4-0.1-0.7
Time in familiar zone, hab. session 20.00.00.10.3-0.1-0.1-0.20.1-0.3-0.0-0.1-0.0-0.1-0.1
Time in novel zone, hab. session 20.10.10.2-0.40.40.30.40.4-0.20.30.4-0.30.40.4
Total zone transitions, hab. session 20.10.10.40.10.10.20.4-0.6-0.00.30.3-0.20.20.5
Total locomotion distance, hab. session 20.70.92.41.2-1.0-0.7-0.8-1.50.7-0.7-0.70.8-0.8-0.7
Locomotion velocity, hab. session 20.81.13.01.3-1.1-0.8-0.9-1.70.9-0.8-0.80.9-0.9-0.8
Novel to familiar place preference ratio0.10.10.20.00.20.40.0-0.2-0.20.30.4-0.20.3-0.2
Novelty place preference0.10.10.3-0.20.40.50.20.0-0.30.50.5-0.30.50.0
Time in novel zone, NPP test0.20.20.4-0.40.50.60.30.1-0.40.50.6-0.40.50.1
Total zone transitions, NPP test1.01.52.41.4-1.3-1.1-1.2-1.51.1-1.1-1.11.2-1.2-1.0
Total locomotion distance, NPP test0.60.81.81.3-1.0-0.7-0.9-1.20.5-0.7-0.60.8-0.7-0.9
Locomotion velocity, NPP test1.11.63.21.8-1.4-1.0-1.4-1.70.8-1.0-1.01.2-1.1-1.3
Intraocular pressure0.50.81.31.1-0.8-1.1-1.0-0.30.4-1.1-1.01.0-1.0-0.7
Delta distance traveled before/after self-admin1.81.93.2-1.41.81.41.51.1-1.61.31.3-1.31.41.0
Delta ambulatory time before/after self-admin0.61.12.1-1.31.51.01.20.9-1.30.90.9-0.91.00.4
Parametrial fat weight1.33.16.3-1.61.72.11.42.5-1.81.71.7-1.61.71.2
Pavlov. Cond. lever latency2.32.94.7-0.81.51.91.71.1-2.21.81.9-2.01.71.9
Pavlov. Cond. magazine entry latency3.03.85.41.2-1.9-2.1-1.9-1.62.3-2.1-2.12.2-2.1-1.7
Pavlov. Cond. change in total contacts0.10.10.4-0.5-0.0-0.3-0.00.20.7-0.3-0.30.4-0.2-0.2
Pavlov. Cond. index score3.64.56.91.2-2.0-2.3-2.0-1.62.6-2.3-2.32.4-2.2-2.0
Pavlov. Cond. latency score2.83.55.80.9-1.7-2.1-1.8-1.32.4-2.0-2.12.1-1.9-1.9
Pavlov. Cond. lever contacts2.02.44.20.6-1.4-1.7-1.4-1.12.0-1.7-1.71.8-1.5-1.7
Pavlov. Cond. magazine entry number3.74.76.0-1.62.22.32.11.9-2.52.32.3-2.32.31.9
Pavlov. Cond. intertrial magazine entries0.20.20.60.70.00.40.20.2-0.70.30.4-0.50.30.7
Pavlov. Cond. lever-magazine prob. diff.3.94.87.11.3-2.1-2.4-2.1-1.72.7-2.4-2.42.4-2.3-2.0
Pavlov. Cond. response bias4.15.16.91.5-2.2-2.4-2.2-1.82.6-2.4-2.42.5-2.4-2.1
Pavlov. Cond. lever latency0.10.20.5-0.70.60.40.40.6-0.30.40.4-0.30.40.2
Pavlov. Cond. magazine entry latency0.10.10.5-0.70.50.40.40.2-0.20.30.4-0.20.30.2
Pavlov. Cond. change in total contacts0.10.30.4-0.50.50.60.60.1-0.30.60.6-0.60.60.6
Pavlov. Cond. index score0.00.00.1-0.1-0.1-0.00.0-0.20.2-0.1-0.00.1-0.10.0
Pavlov. Cond. latency score0.00.00.1-0.20.20.30.3-0.0-0.00.20.2-0.10.20.2
Pavlov. Cond. lever contacts0.00.10.20.4-0.4-0.2-0.2-0.40.2-0.2-0.20.1-0.2-0.0
Pavlov. Cond. magazine entry number0.20.30.40.6-0.5-0.6-0.6-0.30.4-0.4-0.50.4-0.4-0.5
Pavlov. Cond. intertrial magazine entries1.22.63.71.2-1.6-1.8-1.7-1.41.9-1.7-1.71.7-1.8-1.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.0-0.1-0.1-0.0-0.30.2-0.1-0.10.1-0.1-0.0
Pavlov. Cond. response bias0.20.20.30.4-0.5-0.5-0.4-0.50.6-0.5-0.50.5-0.5-0.3
Time in closed arm before self-admin0.10.20.30.6-0.5-0.1-0.5-0.50.5-0.3-0.50.3-0.2-0.5
Time in closed arm after self-admin1.21.32.3-0.80.81.21.30.7-0.81.41.3-1.41.21.5
Time in open arm before self-admin0.40.51.20.2-0.5-0.9-0.8-0.40.5-0.7-0.70.8-1.1-0.7
Time in open arm after self-admin0.50.51.20.3-0.1-0.6-0.8-0.30.2-0.9-0.71.1-1.0-0.9
Bone: periosteal estimation0.61.55.8-2.41.50.91.31.5-0.40.90.9-0.70.90.7
Bone: periosteal perimeter0.10.21.4-1.20.50.00.20.50.30.00.00.10.0-0.1
Bone: post-yield work0.91.62.60.2-1.1-1.5-1.3-0.61.6-1.5-1.41.5-1.4-1.1
Progressive ratio test 1 active lever presses0.30.51.3-0.31.21.00.3-0.1-0.90.70.7-0.70.60.5
Progressive ratio test 1 breakpoint0.30.61.5-0.41.21.10.4-0.0-0.90.80.8-0.70.60.5
Progressive ratio test 1 inactive lever presses0.20.51.0-0.10.81.00.5-0.2-1.00.80.7-0.90.60.8
Progressive ratio test 2 active lever presses0.10.10.20.40.20.4-0.0-0.5-0.40.10.1-0.3-0.10.4
Progressive ratio test 2 breakpoint0.10.10.30.30.20.50.0-0.3-0.50.20.2-0.3-0.10.5
Progressive ratio test 2 inactive lever presses0.20.61.4-0.81.01.20.60.1-0.90.70.7-0.70.40.6
Incentive Sensitization - Responses0.20.51.20.9-0.9-0.6-0.5-1.10.5-0.7-0.70.5-0.9-0.3
Incentive Sensitization - Breakpoint0.20.51.01.0-0.9-0.6-0.5-1.00.4-0.7-0.70.4-0.9-0.3
Sum of active levers in priming session hrs 5-60.50.51.10.5-0.5-0.6-0.4-0.80.5-0.9-0.90.6-1.1-0.7
Progressive ratio3.19.010.7-2.93.23.33.23.1-2.83.02.8-2.92.63.1
Food seeking constrained by brief footshock0.00.00.20.4-0.2-0.2-0.30.1-0.2-0.2-0.10.1-0.1-0.2
Seeking ratio, punishment vs. effort3.27.29.72.8-2.9-3.1-2.9-2.82.3-2.7-2.52.5-2.3-2.7
Retroperitoneal fat weight0.62.74.2-1.61.51.81.62.1-1.41.51.6-1.51.31.9
Reaction time number correct0.20.81.3-0.30.70.70.80.8-1.11.11.1-1.11.10.7
Reaction time mean minus median0.31.93.4-0.1-1.1-1.8-1.20.41.8-1.6-1.51.8-1.7-0.9
Reaction time mean minus median AUC0.31.73.00.2-1.2-1.7-1.10.21.7-1.6-1.51.6-1.6-0.7
Reaction time num false alarms0.10.20.7-0.80.40.80.40.10.00.40.5-0.20.50.0
Reaction time num false alarms AUC0.20.41.1-1.00.70.90.60.1-0.10.60.7-0.40.70.0
Reaction time trials correct on left0.20.81.3-0.30.70.70.80.8-1.11.11.1-1.11.10.7
Reaction time trials on left0.20.81.2-0.30.70.70.80.8-1.11.11.0-1.11.10.7
Reaction time mean1.53.25.40.5-1.6-2.0-1.7-0.82.3-1.9-1.92.3-2.0-1.7
Reaction time mean AUC1.33.15.20.5-1.6-2.0-1.6-0.72.3-2.0-2.02.2-2.0-1.5
Median of all reaction times1.52.44.00.6-1.3-1.6-1.5-1.02.0-1.6-1.61.9-1.7-1.5
Reaction time omissions1.01.62.60.1-0.9-1.5-1.2-0.61.6-1.4-1.31.6-1.6-1.1
Reaction time false alarm rate0.10.20.5-0.70.20.40.0-0.50.6-0.1-0.00.4-0.1-0.5
Reaction time premature initiation rate1.32.12.9-1.61.71.41.41.1-1.21.71.6-1.41.60.8
Reaction time premature initiations1.23.75.3-1.72.11.91.91.5-1.82.32.2-2.12.21.3
Std. dev. reaction times0.51.83.3-0.3-0.9-1.6-1.10.01.8-1.5-1.51.8-1.6-1.0
Reaction time trials completed0.20.81.2-0.30.70.70.80.8-1.11.11.0-1.11.10.7
Reaction time trials AUC0.20.71.1-0.20.70.60.70.7-1.01.01.0-1.01.00.6
Run reversals in cocaine runway, females0.20.21.00.00.60.60.2-0.2-1.00.50.6-0.50.3-0.1
Run reversals in cocaine runway, males0.30.41.8-1.40.7-0.10.21.20.20.20.20.2-0.2-0.1
Latency to leave start box in cocaine runway0.10.20.40.2-0.5-0.5-0.2-0.60.4-0.5-0.50.1-0.2-0.1
Latency to leave start box in cocaine runway, F0.60.71.30.6-1.0-1.0-0.9-0.60.9-0.8-0.80.7-0.6-1.1
Latency to leave start box in cocaine runway, M0.90.92.7-0.80.80.81.20.5-0.90.60.6-1.20.71.6
Std. dev. time between licks in bursts0.61.12.4-0.2-0.7-1.2-0.8-1.01.6-1.1-1.21.2-1.1-1.1
Total sessions with >9 infusions0.70.91.5-0.91.21.20.80.6-1.11.00.9-0.90.71.0
Short access day 1 total inactive lever presses0.71.43.7-1.91.30.91.21.3-0.71.21.2-0.90.91.1
Short access day 10 total inactive lever presses0.10.71.10.6-0.7-0.9-0.8-1.00.5-1.0-1.00.5-0.6-1.0
Short access day 1 total infusions0.10.10.3-0.20.40.60.2-0.2-0.20.30.3-0.1-0.00.6
Short access day 10 total infusions0.50.81.6-0.61.01.30.70.5-1.11.01.0-0.80.70.9
Short access total infusions0.91.32.5-1.01.51.60.90.6-1.31.31.3-1.00.81.2
Short access day 1 locomotion0.71.22.41.3-1.0-0.9-1.0-1.60.9-1.2-1.20.8-1.2-0.4
Short access day 10 total locomotion0.00.10.3-0.50.10.40.4-0.30.5-0.1-0.1-0.20.20.3
Short access total locomotion0.00.10.5-0.10.20.20.0-0.70.3-0.1-0.1-0.1-0.00.1
One hour access (0.3 mA shock)1.01.23.11.3-0.8-0.4-1.2-1.80.4-1.1-1.10.9-1.2-1.1
Compulsive drug intake4.26.28.82.1-2.2-2.3-2.6-2.92.3-2.6-2.62.3-2.2-3.0
One hour access (shock baseline)0.51.32.3-0.71.11.41.11.1-1.51.01.1-1.00.51.4
Social response proportion0.00.00.1-0.30.1-0.10.1-0.20.3-0.1-0.10.3-0.1-0.1
Social responses0.20.30.7-0.60.50.40.7-0.1-0.20.40.4-0.50.60.9
Social time0.71.12.3-0.3-0.7-1.0-0.8-0.51.5-1.2-1.21.3-1.1-1.2
Soleus weight0.41.12.5-0.8-0.3-0.8-0.8-1.01.6-0.9-1.01.3-0.9-1.4
Bone: stiffness1.12.02.7-1.11.31.41.51.6-1.51.31.4-1.41.41.6
Tibialis anterior weight0.30.91.8-0.20.81.20.70.9-1.31.01.1-1.11.10.7
Time to tail flick, vehicle, before self-admin1.01.21.91.0-1.3-0.8-1.3-0.31.2-1.3-1.41.0-0.7-1.0
Time to tail flick, vehicle, after self-admin0.61.21.80.8-1.1-0.8-1.1-0.71.2-1.3-1.31.2-1.3-1.1
Time to tail flick, test, before self-admin0.10.10.30.1-0.10.0-0.20.5-0.1-0.3-0.30.1-0.3-0.2
Time to tail flick, test, after self-admin0.70.71.20.7-1.1-1.0-0.80.20.9-1.0-0.90.9-1.1-0.4
Delta time to tail flick, vehicle, before/after SA0.00.00.20.2-0.0-0.10.1-0.2-0.30.00.10.0-0.40.2
Delta time to tail flick, test, before/after SA0.30.30.70.8-0.8-0.7-0.5-0.60.6-0.5-0.40.4-0.4-0.3
Tibia length0.92.67.1-2.71.81.21.82.1-0.61.31.4-1.01.21.6
Ambulatory time before self-admin0.00.10.3-0.30.10.50.00.60.20.20.20.10.20.1
Ambulatory time after self-admin0.61.02.2-1.41.51.10.81.1-1.00.70.7-0.50.90.0
Bone: tissue strength4.34.55.5-2.32.42.12.02.4-2.12.12.1-2.02.21.5
Total heroin consumption0.10.10.4-0.10.30.0-0.3-0.0-0.1-0.5-0.50.3-0.3-0.6
Bone: trabecular number0.40.82.81.7-1.1-0.6-1.0-0.70.2-0.7-0.70.6-0.7-0.8
Bone: trabecular spacing2.02.96.0-2.42.01.51.81.8-1.21.61.6-1.41.61.4
Bone: trabecular thickness0.50.61.91.4-1.0-0.7-0.9-0.40.3-0.8-0.80.6-0.8-0.6
Bone: trabecular tissue density1.42.54.1-1.61.51.52.01.3-1.31.41.4-1.71.52.0
Water consumed over 24 hours0.00.00.1-0.0-0.1-0.0-0.1-0.00.1-0.1-0.00.1-0.0-0.3
Number of responses in last shaping day0.30.41.0-1.00.90.80.7-0.0-0.20.50.5-0.30.50.4