Hub : Genes

LOC134483844

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression LOC134483844 0.89 0.02 2.8e-16 0.28 0.25 0.27 0.27 4.1e-12 7.5e-11 9.4e-12 1.3e-11
2 pVTA gene expression LOC134483844 0.57 0.11 0.0e+00 0.3 0.26 0.3 0.3 6.6e-25 3.0e-21 2.0e-24 3.9e-24
3 PL gene expression LOC134483844 0.72 0.08 0.0e+00 0.47 0.45 0.48 0.48 8.8e-58 1.1e-54 6.2e-59 5.9e-59
4 OFC gene expression LOC134483844 0.69 0.22 1.8e-05 0.23 0.19 0.2 0.22 4.4e-06 3.0e-05 1.7e-05 7.7e-06
5 Brain gene expression LOC134483844 0.57 0.13 0.0e+00 0.19 0.17 0.17 0.16 1.5e-17 4.7e-16 1.2e-15 2.5e-14
6 BLA gene expression LOC134483844 0.85 0.06 0.0e+00 0.39 0.36 0.4 0.38 7.5e-22 5.9e-20 2.7e-22 1.4e-21
7 Adipose gene expression LOC134483844 0.08 0.07 2.8e-04 0.01 0.02 0.01 0.02 1.9e-02 6.0e-03 4.3e-02 3.5e-03
8 NAcc gene expression LOC134483844 0.46 0.09 0.0e+00 0.23 0.19 0.22 0.22 2.1e-34 7.0e-28 1.7e-32 5.5e-33
9 Liver gene expression LOC134483844 0.13 0.07 7.0e-10 0.08 0.06 0.06 0.07 8.8e-09 9.7e-08 1.2e-07 2.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.42.43.21.71.71.81.71.71.70.81.70.8
Area under the delay curve2.32.73.1-1.6-1.6-1.6-1.6-1.6-1.7-1.7-1.6-1.8
BMI with tail1.24.36.9-1.9-1.9-1.6-2.0-2.1-1.8-2.6-2.0-2.5
BMI without tail3.510.813.1-3.4-3.4-3.0-3.4-3.4-3.0-3.6-2.7-3.4
Body weight7.131.036.1-6.0-6.0-5.9-5.9-5.9-5.7-4.6-5.7-4.0
Weight adjusted by age2.53.84.9-2.0-2.0-2.2-2.1-2.1-2.1-1.2-2.2-1.1
Bone surface0.10.10.3-0.5-0.5-0.5-0.5-0.5-0.2-0.00.10.1
Bone volume0.00.10.2-0.3-0.3-0.2-0.2-0.2-0.1-0.40.0-0.3
Breakpoint value in progressive ratio session0.30.30.50.60.60.50.50.50.50.60.30.7
Number of licking bursts0.10.20.70.30.30.20.30.30.40.90.40.7
Context. condit. distance diff. score6.67.912.62.52.52.32.62.62.73.62.83.5
Locomotion velocity, session 10.40.41.20.50.50.40.40.40.51.00.41.1
Locomotion distance, session 10.40.50.80.90.90.90.80.80.60.20.50.2
Locomotion velocity, session 20.00.00.10.00.0-0.1-0.1-0.1-0.20.3-0.20.2
Locomotion distance, session 20.30.40.50.70.70.60.60.60.40.60.20.6
Locomotion velocity, session 30.00.00.10.00.00.10.00.00.0-0.30.0-0.0
Locomotion distance, session 31.51.61.91.21.21.31.31.31.41.11.41.2
Stereotopy head waving bouts, day 31.82.13.1-1.6-1.6-1.8-1.6-1.6-1.6-0.4-1.6-0.1
Stereotopy head waving duration, day 31.41.72.3-1.4-1.4-1.5-1.4-1.4-1.5-0.5-1.5-0.4
Locomotion velocity, session 75.05.55.92.42.42.32.32.32.42.32.42.3
Locomotion distance, session 74.15.26.72.42.42.52.32.32.51.82.61.6
Stereotopy head waving bouts, day 73.33.74.5-2.1-2.1-2.1-2.1-2.1-2.1-1.3-2.0-1.0
Stereotopy head waving duration, day 73.34.04.7-2.2-2.2-2.2-2.1-2.1-2.2-1.4-2.1-1.2
Locomotion velocity, session 80.50.72.4-0.3-0.3-0.7-0.3-0.3-0.41.5-0.51.5
Locomotion distance, session 83.65.38.72.12.11.92.12.12.12.92.12.9
Degree of sensitization distance0.30.30.70.60.60.40.40.40.50.80.60.6
Degree of sensitization stereotypy1.31.41.8-1.3-1.3-1.3-1.3-1.3-1.3-0.9-1.3-0.5
Conditioned locomotion1.01.12.0-1.0-1.0-1.1-1.1-1.1-1.3-0.6-1.4-0.7
Cocaine response after cond. corrected0.60.71.00.90.90.91.01.00.90.60.70.5
Cocaine response after cond. not corrected0.10.10.3-0.3-0.3-0.4-0.2-0.2-0.30.2-0.50.1
Cocaine response before conditioning5.46.48.2-2.8-2.8-2.9-2.9-2.9-2.7-1.5-2.6-1.4
Saline control response1.62.14.7-1.3-1.3-1.0-1.3-1.3-1.1-2.1-1.1-2.2
Bone: connectivity density2.84.45.12.22.22.22.12.12.31.82.21.7
Bone: cortical apparent density0.40.61.9-0.3-0.3-0.2-0.5-0.5-0.5-1.3-0.6-1.4
Bone: cortical area1.82.73.2-1.8-1.8-1.8-1.7-1.7-1.7-1.4-1.7-1.2
Bone: cortical porosity0.91.01.1-1.0-1.0-0.9-1.0-1.0-0.8-1.1-1.0-1.0
Bone: cortical porosity0.80.81.0-1.0-1.0-1.0-1.0-1.0-0.8-0.7-0.9-0.7
Bone: cortical thickness2.74.58.1-1.9-1.9-1.7-1.9-1.9-2.0-2.8-2.1-2.6
Bone: cortical thickness0.70.92.8-0.5-0.5-0.3-0.6-0.6-0.6-1.7-0.7-1.6
Bone: cortical tissue density0.30.41.6-0.3-0.3-0.1-0.4-0.4-0.5-1.2-0.5-1.3
Condit. Reinf. active minus inactive responses0.91.01.31.21.21.01.01.10.81.00.71.0
Condit. Reinf. active-inactive response ratio0.10.10.30.10.10.10.00.0-0.1-0.5-0.2-0.6
Condit. Reinf. active responses1.72.12.51.61.61.51.51.51.31.41.21.5
Condit. Reinf. inactive responses2.83.43.91.91.92.01.92.01.91.41.91.5
Incentive salience index mean1.72.13.41.51.51.21.41.41.21.81.11.8
Condit. Reinf. lever presses3.14.47.91.91.91.61.91.91.82.81.82.8
Condit. Reinf. active minus inactive responses1.41.82.2-1.4-1.4-1.4-1.5-1.5-1.4-1.0-1.4-1.1
Condit. Reinf. active-inactive response ratio2.93.44.1-1.9-1.9-2.0-2.0-2.0-2.0-1.1-2.0-1.2
Condit. Reinf. active responses0.00.00.00.10.10.0-0.0-0.00.10.10.20.1
Condit. Reinf. inactive responses1.82.43.31.61.61.71.61.61.71.11.81.1
Condit. Reinf. lever presses0.71.01.40.90.90.90.90.91.01.11.21.2
Condit. Reinf. lever reinforcers received0.00.10.20.20.20.20.10.10.20.40.40.3
Conditioned reinforcement - actives0.81.41.5-1.2-1.2-1.0-1.2-1.2-1.2-1.2-1.2-1.2
Conditioned reinforcement - inactives1.42.02.6-1.4-1.4-1.3-1.4-1.4-1.4-1.5-1.6-1.2
Conditioned locomotion0.20.20.4-0.4-0.5-0.4-0.5-0.5-0.5-0.3-0.7-0.6
Patch foraging indifference point 0 sec0.20.41.1-0.7-0.7-0.3-0.5-0.5-0.3-1.0-0.4-0.6
Patch foraging indifference point AUC1.11.52.0-1.3-1.3-1.2-1.4-1.4-1.2-1.2-1.0-1.1
Delay disc. indifference point, 0s delay0.80.91.2-1.0-1.0-1.1-1.1-1.1-1.0-0.6-0.9-0.6
Delay disc. indifference point, 16s delay1.71.94.0-1.3-1.3-1.0-1.1-1.1-1.1-2.0-1.0-2.0
Delay disc. indifference point, 2s delay2.32.63.0-1.6-1.6-1.7-1.6-1.6-1.7-1.3-1.7-1.4
Delay disc. indifference point, 24s delay0.40.41.1-0.6-0.6-0.5-0.3-0.3-0.5-1.0-0.3-1.1
Delay disc. indifference point, 4s delay4.44.66.2-2.0-2.0-2.2-2.2-2.2-2.3-1.7-2.5-2.0
Delay disc. indifference point, 8s delay0.50.50.7-0.7-0.7-0.7-0.6-0.6-0.7-0.9-0.7-0.8
Indifference point function ln k0.20.41.10.30.30.20.60.60.30.90.51.1
Indifference point function log k0.20.41.10.30.30.20.60.60.30.90.51.1
Patch foraging total patch changes 0 sec0.30.61.7-0.8-0.8-0.4-0.7-0.7-0.5-1.3-0.5-0.8
Patch foraging total patch changes 12 sec0.81.02.8-0.8-0.8-0.5-1.0-1.0-0.6-1.7-0.6-1.6
Patch foraging total patch changes 18 sec0.10.21.2-0.0-0.00.40.00.00.3-1.10.2-0.7
Patch foraging total patch changes 24 sec0.40.61.20.70.71.10.80.80.9-0.70.8-0.6
Patch foraging total patch changes 6 sec0.50.82.9-0.5-0.5-0.2-0.6-0.6-0.4-1.7-0.4-1.7
Patch foraging time to switch 0 sec0.10.30.50.60.60.70.60.60.6-0.20.4-0.3
Patch foraging water rate 0 sec0.40.91.1-0.9-0.9-0.9-0.8-0.8-1.0-0.9-1.1-1.0
Patch foraging water rate 12 sec0.10.10.40.30.30.40.60.60.1-0.2-0.1-0.3
Patch foraging water rate 18 sec0.30.40.6-0.7-0.7-0.8-0.6-0.6-0.7-0.2-0.8-0.2
Patch foraging water rate 24 sec1.42.02.5-1.6-1.6-1.5-1.4-1.4-1.5-1.3-1.4-1.0
Patch foraging water rate 6 sec0.10.10.6-0.1-0.10.00.20.2-0.0-0.70.1-0.8
Seeking ratio, delayed vs. immediate footshock0.60.71.0-0.9-0.9-0.9-0.7-0.7-0.9-0.7-1.0-0.7
Distance traveled before self-admin0.20.30.5-0.4-0.4-0.6-0.6-0.6-0.50.4-0.50.7
Distance traveled after self-admin0.91.21.7-1.2-1.2-1.3-1.3-1.3-1.0-0.2-1.10.1
Extensor digitorum longus weight0.00.20.7-0.2-0.2-0.1-0.1-0.10.30.60.40.9
Bone: elastic displacement0.30.41.0-0.4-0.4-0.3-0.4-0.4-0.5-1.0-0.6-1.0
Bone: elastic work2.22.83.2-1.7-1.7-1.6-1.7-1.7-1.7-1.7-1.8-1.6
Bone: endosteal estimation1.83.96.9-2.3-2.3-2.6-2.2-2.2-2.10.0-1.80.2
Bone: endosteal perimeter0.30.62.4-0.4-0.4-0.7-0.3-0.3-0.11.50.01.5
Epididymis fat weight1.65.520.3-1.2-1.2-0.4-1.3-1.3-1.2-4.5-1.4-4.5
Delta time in closed arm before/after self-admin0.50.50.8-0.7-0.7-0.6-0.6-0.6-0.6-0.9-0.5-0.9
Delta time in open arm before/after self-admin0.40.41.0-0.6-0.6-0.7-0.5-0.5-0.8-0.2-1.0-0.2
Diff in mean of infusions in LGA sessions4.04.86.02.42.42.42.32.32.31.62.21.5
Delay discount exponential model param2.42.73.41.61.61.61.61.61.71.71.61.8
Extinction: sum of active levers before priming0.60.61.20.60.60.60.80.80.80.90.71.1
Active lever presses in extinction session 60.30.30.70.40.40.60.50.50.5-0.40.8-0.5
Bone: final force5.48.69.6-3.1-3.1-2.8-3.0-3.0-2.8-3.1-2.6-2.8
Bone: final moment4.87.78.6-2.9-2.9-2.7-2.9-2.9-2.7-2.9-2.5-2.6
Food consumed during 24 hour testing period0.60.81.4-1.0-1.0-1.2-1.0-1.0-1.1-0.2-0.9-0.3
Glucose1.01.66.20.60.60.10.60.60.62.50.42.4
Heart weight1.42.22.9-1.4-1.4-1.3-1.6-1.6-1.4-1.6-1.3-1.7
Delay discount hyperbolic model param2.62.93.61.61.61.61.71.71.71.71.71.9
Intermittent access intake day 1-15 change0.10.20.40.60.70.50.60.50.40.40.5-0.1
Intermittent access intake escalation0.00.10.60.20.30.10.30.2-0.0-0.20.1-0.8
Intermittent access intake escalation 20.10.10.50.20.30.00.30.30.10.70.20.2
Intermitt. access day 1 inactive lever presses0.10.30.8-0.5-0.5-0.6-0.6-0.6-0.50.2-0.90.4
Intermitt. access day 15 inactive lever presses0.61.21.8-1.2-1.3-1.2-1.2-1.3-1.0-0.7-1.0-0.4
Intermitt. access escalation Index2.23.13.71.91.81.71.91.91.81.51.81.4
Intermittent access day 1 total infusions0.00.00.10.20.10.3-0.00.10.1-0.3-0.0-0.2
Intermittent access day 15 total infusions0.10.21.2-0.1-0.1-0.1-0.2-0.2-0.4-0.7-0.3-1.1
Intermittent access terminal intake (last 3 days)0.30.41.5-0.5-0.4-0.4-0.5-0.5-0.6-0.9-0.6-1.2
Intermittent access total infusions0.20.30.8-0.4-0.4-0.3-0.5-0.4-0.5-0.7-0.4-0.9
Intermittent access day 1 locomotion0.00.10.3-0.0-0.0-0.0-0.00.0-0.2-0.3-0.0-0.6
Intermittent access day 15 total locomotion1.22.23.3-1.4-1.4-1.5-1.5-1.5-1.6-1.2-1.4-1.8
Intermittent access total locomotion1.61.92.5-1.3-1.3-1.4-1.4-1.3-1.5-1.2-1.3-1.6
Intermittent access standard deviation1.12.32.8-1.4-1.4-1.4-1.5-1.5-1.6-1.6-1.6-1.7
Left kidney weight4.822.225.1-4.9-4.9-4.7-5.0-5.0-4.7-4.2-4.8-3.9
Right kidney weight5.625.428.4-5.2-5.2-5.1-5.3-5.3-5.1-4.5-5.1-4.4
Cocaine induced anxiety0.40.61.40.70.70.60.60.60.71.10.71.2
Post-drug Anxiety0.50.61.00.70.60.70.60.60.80.81.00.9
Baseline Anxiety0.50.51.10.80.71.00.70.70.90.01.0-0.0
Tail length4.517.525.0-4.7-4.7-5.0-4.5-4.5-4.5-2.4-4.1-2.1
Length with tail6.126.738.0-5.8-5.8-6.2-5.7-5.6-5.5-2.8-5.3-2.3
Length without tail5.417.522.7-4.6-4.6-4.8-4.5-4.4-4.6-2.6-4.5-2.1
Times rat made contact with spout1.51.72.61.41.41.61.51.51.50.21.50.1
Lifetime Intake0.60.71.0-0.8-0.8-0.7-0.9-0.9-0.8-1.0-0.7-1.0
Liver weight, left0.71.12.1-1.1-1.1-1.5-1.1-1.1-1.20.4-1.10.3
Liver weight, right2.64.67.3-2.4-2.4-2.7-2.4-2.4-2.3-0.7-2.0-0.8
Locomotor activity0.91.42.6-1.3-1.3-1.6-1.3-1.3-1.00.4-1.20.5
Locomotor testing distance0.20.30.6-0.5-0.5-0.6-0.5-0.5-0.10.6-0.30.8
Locomotor testing rearing0.30.71.2-0.9-0.9-1.1-0.9-0.9-0.8-0.1-0.9-0.1
Locomotion in novel chamber0.60.81.1-1.0-1.0-1.0-1.1-1.1-0.8-0.7-0.7-0.2
Locomotion in novel chamber post-restriction0.81.31.5-1.1-1.1-1.1-1.1-1.1-1.2-1.1-1.2-1.1
Fecal boli incidents, locomotor time 10.81.21.41.11.11.10.90.91.11.01.21.2
Change in fecal boli incidents, locomotor task0.80.81.3-0.8-0.8-0.8-0.9-0.9-1.0-0.7-1.2-0.9
Time >=10cm from walls, locomotor time 10.50.50.9-0.8-0.8-1.0-0.7-0.7-0.80.2-0.80.1
Bouts of movement, locomotor time 11.01.11.51.11.10.91.01.01.01.20.91.2
Total resting periods, locomotor time 10.50.50.90.80.80.50.70.70.51.00.50.9
Rest time, locomotor task time 10.10.10.3-0.2-0.2-0.4-0.2-0.2-0.50.3-0.50.0
Distance moved, locomotor task time 10.30.40.6-0.7-0.7-0.5-0.7-0.7-0.4-0.8-0.3-0.6
Vertical activity count, locomotor time 10.10.30.5-0.6-0.6-0.4-0.6-0.6-0.3-0.7-0.4-0.5
Time >=10cm from walls, locomotor time 20.10.10.2-0.2-0.2-0.3-0.2-0.2-0.40.0-0.4-0.1
Bouts of movement, locomotor time 20.60.92.0-0.9-0.9-1.2-0.9-0.9-1.2-0.0-1.4-0.1
Total resting periods, locomotor time 20.40.61.6-0.7-0.7-1.1-0.7-0.7-1.00.4-1.30.2
Rest time, locomotor task time 20.50.73.00.40.40.00.40.40.21.7-0.01.5
Distance moved, locomotor task time 21.01.23.7-0.8-0.8-0.6-0.9-0.9-0.7-1.9-0.7-1.8
Vertical activity count, locomotor time 20.20.21.0-0.1-0.10.1-0.1-0.10.0-1.0-0.0-1.0
Light reinforcement 10.00.10.2-0.2-0.2-0.1-0.3-0.3-0.2-0.5-0.1-0.3
Light reinforcement 20.81.21.9-1.1-1.1-1.2-1.2-1.2-1.4-0.6-1.2-0.7
Bone: marrow area1.83.96.9-2.3-2.3-2.6-2.2-2.2-2.10.0-1.80.1
Bone: maximum diameter0.40.71.2-0.9-0.9-1.1-0.9-0.9-0.60.6-0.60.7
Bone: maximum force4.37.78.4-2.9-2.9-2.7-2.8-2.8-2.7-2.8-2.5-2.7
Bone: maximum moment3.96.87.7-2.8-2.8-2.6-2.7-2.7-2.5-2.6-2.4-2.4
Mean time between licks in bursts0.10.31.4-0.1-0.1-0.4-0.1-0.1-0.01.2-0.01.1
Mean num. licks in bursts0.20.30.50.40.40.60.40.40.4-0.70.4-0.7
Cd content in liver0.10.10.70.10.10.1-0.0-0.0-0.2-0.5-0.4-0.8
Co content in liver0.80.92.3-0.7-0.7-0.6-0.7-0.7-0.8-1.4-0.8-1.5
Cu content in liver2.12.53.71.71.71.91.81.71.80.31.90.1
Fe content in liver0.70.82.6-0.6-0.6-0.5-0.6-0.6-0.7-1.5-0.8-1.6
K content in liver0.40.41.10.50.50.70.60.60.90.31.00.5
Mg content in liver1.31.32.11.01.01.01.21.11.31.21.51.1
Mn content in liver2.73.06.51.41.41.11.51.51.62.51.62.5
Na content in liver0.40.42.3-0.2-0.20.0-0.1-0.2-0.1-1.3-0.1-1.5
Rb content in liver1.21.42.81.11.11.31.21.21.50.61.70.4
Se content in liver0.20.20.90.40.40.10.40.30.30.90.10.4
Sr content in liver0.60.50.7-0.8-0.8-0.8-0.8-0.8-0.8-0.3-0.8-0.3
Zn content in liver0.00.00.10.10.10.10.20.10.30.30.30.2
Bone: minimum diameter0.51.01.8-1.1-1.1-1.4-1.0-1.0-0.90.7-0.90.9
Time in familiar zone, hab. session 12.62.53.81.81.82.01.81.81.70.51.50.3
Time in novel zone, hab. session 11.41.42.2-1.4-1.4-1.5-1.4-1.4-1.2-0.2-1.0-0.0
Total zone transitions, hab. session 10.91.22.01.01.01.01.01.01.11.21.11.4
Total locomotion distance, hab. session 10.60.82.10.80.80.80.80.80.81.00.71.4
Locomotion velocity, hab. session 10.20.31.00.50.50.50.50.50.50.60.41.0
Time in familiar zone, hab. session 20.10.10.20.30.30.40.40.40.4-0.10.4-0.1
Time in novel zone, hab. session 20.10.10.2-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.4-0.2
Total zone transitions, hab. session 20.00.00.00.20.20.10.10.1-0.0-0.2-0.1-0.2
Total locomotion distance, hab. session 21.01.31.51.21.21.21.21.21.01.01.01.1
Locomotion velocity, hab. session 21.11.41.71.31.31.31.31.31.11.11.01.2
Novel to familiar place preference ratio0.00.00.10.00.00.20.10.10.2-0.00.30.2
Novelty place preference0.00.00.1-0.2-0.2-0.1-0.2-0.2-0.1-0.20.00.0
Time in novel zone, NPP test0.10.10.2-0.4-0.4-0.3-0.4-0.4-0.3-0.3-0.1-0.0
Total zone transitions, NPP test1.21.72.01.41.41.31.31.31.21.31.11.3
Total locomotion distance, NPP test1.11.61.81.41.41.41.31.31.21.01.11.2
Locomotion velocity, NPP test2.02.83.31.81.81.81.81.81.71.41.51.6
Intraocular pressure0.71.01.31.11.11.01.11.10.91.00.80.9
Delta distance traveled before/after self-admin1.71.82.2-1.5-1.5-1.3-1.5-1.5-1.2-1.2-1.3-1.1
Delta ambulatory time before/after self-admin1.31.62.2-1.5-1.5-1.4-1.4-1.4-1.2-0.9-1.3-0.7
Parametrial fat weight1.02.33.0-1.6-1.6-1.4-1.7-1.7-1.3-1.5-1.2-1.5
Pavlov. Cond. lever latency0.91.13.9-0.7-0.7-0.3-0.6-0.7-0.6-2.0-0.5-2.0
Pavlov. Cond. magazine entry latency1.41.84.41.21.20.81.11.11.02.10.91.9
Pavlov. Cond. change in total contacts0.30.30.5-0.5-0.5-0.7-0.5-0.5-0.60.4-0.60.3
Pavlov. Cond. index score1.51.95.51.11.10.71.01.10.92.40.82.2
Pavlov. Cond. latency score1.11.44.50.80.80.40.70.80.72.10.62.0
Pavlov. Cond. lever contacts0.70.93.30.50.50.20.40.50.41.80.31.8
Pavlov. Cond. magazine entry number2.22.75.3-1.6-1.6-1.3-1.5-1.5-1.4-2.3-1.3-2.1
Pavlov. Cond. intertrial magazine entries0.40.50.90.80.81.00.70.70.7-0.50.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.82.25.71.31.30.91.21.21.12.41.02.2
Pavlov. Cond. response bias2.02.45.91.41.41.01.31.31.22.41.12.2
Pavlov. Cond. lever latency0.30.40.5-0.7-0.7-0.7-0.7-0.7-0.6-0.3-0.6-0.2
Pavlov. Cond. magazine entry latency0.30.40.6-0.7-0.7-0.8-0.7-0.7-0.7-0.2-0.7-0.1
Pavlov. Cond. change in total contacts0.10.20.4-0.4-0.4-0.3-0.4-0.4-0.4-0.6-0.3-0.6
Pavlov. Cond. index score0.00.00.0-0.1-0.1-0.1-0.0-0.0-0.10.1-0.10.1
Pavlov. Cond. latency score0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.3-0.1-0.3-0.1
Pavlov. Cond. lever contacts0.10.10.20.50.50.50.40.40.40.10.30.1
Pavlov. Cond. magazine entry number0.30.30.50.60.60.60.60.60.70.40.70.3
Pavlov. Cond. intertrial magazine entries0.81.32.11.11.10.91.11.11.11.51.11.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.00.0-0.00.00.0-0.00.1-0.00.1
Pavlov. Cond. response bias0.10.10.20.40.40.30.40.40.30.50.30.4
Time in closed arm before self-admin0.20.20.30.50.50.50.40.40.60.50.50.3
Time in closed arm after self-admin0.80.93.2-0.7-0.7-0.5-0.7-0.7-0.6-1.5-0.4-1.8
Time in open arm before self-admin0.20.20.50.20.20.20.30.30.40.50.70.7
Time in open arm after self-admin0.20.31.20.20.2-0.00.20.20.01.0-0.11.1
Bone: periosteal estimation2.24.77.1-2.5-2.5-2.7-2.4-2.4-2.3-0.9-2.2-0.7
Bone: periosteal perimeter0.71.12.0-1.2-1.2-1.4-1.1-1.1-1.1-0.1-1.1-0.1
Bone: post-yield work0.30.41.70.10.1-0.10.10.10.31.30.41.1
Progressive ratio test 1 active lever presses0.20.30.7-0.3-0.4-0.2-0.5-0.4-0.4-0.8-0.4-0.8
Progressive ratio test 1 breakpoint0.20.30.7-0.4-0.4-0.2-0.5-0.5-0.5-0.8-0.4-0.8
Progressive ratio test 1 inactive lever presses0.10.20.9-0.0-0.10.3-0.0-0.00.1-0.90.2-0.9
Progressive ratio test 2 active lever presses0.10.10.40.40.40.5-0.00.00.2-0.3-0.0-0.6
Progressive ratio test 2 breakpoint0.10.10.50.40.40.5-0.1-0.00.1-0.4-0.0-0.7
Progressive ratio test 2 inactive lever presses0.30.50.6-0.8-0.8-0.7-0.8-0.8-0.7-0.6-0.6-0.6
Incentive Sensitization - Responses0.40.51.11.01.00.90.60.60.80.60.50.3
Incentive Sensitization - Breakpoint0.50.61.21.01.11.00.60.70.80.60.60.2
Sum of active levers in priming session hrs 5-60.30.30.50.60.50.40.70.70.40.50.40.3
Progressive ratio5.18.08.8-2.9-2.9-2.8-2.7-2.7-2.9-3.0-2.8-2.8
Food seeking constrained by brief footshock0.20.20.60.60.60.60.30.30.50.20.80.2
Seeking ratio, punishment vs. effort4.97.17.92.82.82.72.62.62.82.52.82.3
Retroperitoneal fat weight0.62.73.5-1.6-1.7-1.5-1.8-1.8-1.5-1.7-1.5-1.9
Reaction time number correct0.10.31.2-0.2-0.2-0.0-0.0-0.0-0.2-1.1-0.0-1.1
Reaction time mean minus median0.20.62.0-0.3-0.3-0.7-0.3-0.3-0.41.4-0.61.3
Reaction time mean minus median AUC0.10.31.40.10.1-0.3-0.1-0.1-0.21.2-0.40.9
Reaction time num false alarms0.40.61.0-0.8-0.8-0.9-0.8-0.8-0.9-0.1-1.00.1
Reaction time num false alarms AUC0.60.91.3-1.0-1.0-1.1-1.0-1.0-1.0-0.3-1.1-0.0
Reaction time trials correct on left0.10.31.2-0.2-0.2-0.0-0.0-0.0-0.2-1.1-0.0-1.1
Reaction time trials on left0.20.31.2-0.2-0.2-0.1-0.1-0.1-0.3-1.1-0.1-1.1
Reaction time mean0.61.04.50.40.4-0.10.40.40.32.0-0.12.1
Reaction time mean AUC0.60.93.90.40.4-0.10.40.40.22.0-0.22.0
Median of all reaction times0.60.93.70.50.50.10.50.50.41.80.11.9
Reaction time omissions0.20.41.5-0.0-0.0-0.3-0.1-0.1-0.21.2-0.31.2
Reaction time false alarm rate0.50.61.0-0.8-0.8-1.0-0.8-0.8-0.80.4-1.00.7
Reaction time premature initiation rate1.42.02.6-1.6-1.6-1.4-1.5-1.5-1.2-1.4-1.0-1.1
Reaction time premature initiations1.42.53.9-1.7-1.7-1.4-1.5-1.5-1.4-2.0-1.1-1.7
Std. dev. reaction times0.40.81.9-0.5-0.5-1.0-0.6-0.6-0.61.4-1.01.4
Reaction time trials completed0.20.31.2-0.2-0.2-0.1-0.1-0.1-0.3-1.1-0.1-1.1
Reaction time trials AUC0.10.31.1-0.2-0.20.00.00.0-0.2-1.10.1-1.0
Run reversals in cocaine runway, females0.10.10.30.00.00.20.0-0.10.2-0.30.50.1
Run reversals in cocaine runway, males1.71.73.0-1.5-1.5-1.7-1.3-1.3-1.5-0.1-1.50.3
Latency to leave start box in cocaine runway0.10.10.30.20.20.30.20.20.40.20.5-0.1
Latency to leave start box in cocaine runway, F0.50.50.90.60.60.70.60.60.90.81.00.8
Latency to leave start box in cocaine runway, M0.90.92.4-0.8-0.8-0.7-0.8-0.8-0.8-1.1-0.7-1.6
Std. dev. time between licks in bursts0.20.30.9-0.3-0.3-0.6-0.4-0.4-0.30.9-0.10.9
Total sessions with >9 infusions0.60.70.9-0.8-0.9-0.8-0.9-0.9-0.8-0.9-0.8-0.9
Short access day 1 total inactive lever presses2.53.34.4-2.0-2.0-2.1-1.9-1.9-1.9-1.0-2.0-0.9
Short access day 10 total inactive lever presses0.20.51.00.60.60.70.80.70.90.80.51.0
Short access day 1 total infusions0.00.10.2-0.2-0.3-0.2-0.3-0.3-0.2-0.2-0.4-0.1
Short access day 10 total infusions0.30.40.7-0.6-0.6-0.5-0.8-0.8-0.5-0.7-0.4-0.7
Short access total infusions0.81.01.4-1.0-1.1-0.9-1.2-1.1-0.9-1.1-0.9-0.9
Short access day 1 locomotion1.11.41.91.41.41.31.41.31.20.91.00.5
Short access day 10 total locomotion0.20.30.5-0.5-0.5-0.7-0.6-0.5-0.7-0.0-0.6-0.3
Short access total locomotion0.00.00.1-0.1-0.1-0.1-0.2-0.1-0.10.0-0.1-0.3
One hour access (0.3 mA shock)1.51.72.31.41.41.51.21.21.41.01.50.9
Compulsive drug intake3.94.66.62.12.02.12.02.02.22.32.12.6
One hour access (shock baseline)0.50.72.2-0.7-0.6-0.6-0.7-0.7-0.8-1.1-0.6-1.5
Social response proportion0.10.10.3-0.3-0.3-0.5-0.3-0.3-0.40.2-0.50.3
Social responses0.30.40.6-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.8
Social time0.30.41.4-0.3-0.3-0.6-0.4-0.4-0.31.2-0.21.1
Soleus weight0.30.81.8-0.9-0.9-1.2-0.7-0.7-0.51.1-0.31.4
Bone: stiffness0.81.32.4-1.1-1.1-1.0-1.0-1.0-1.0-1.5-0.8-1.6
Tibialis anterior weight0.10.20.9-0.1-0.10.30.00.00.3-1.00.5-0.9
Time to tail flick, vehicle, before self-admin1.01.01.41.00.91.00.90.91.21.11.11.0
Time to tail flick, vehicle, after self-admin0.50.61.40.70.70.60.60.60.81.20.71.0
Time to tail flick, test, before self-admin0.00.00.20.10.10.20.20.20.3-0.00.4-0.1
Time to tail flick, test, after self-admin0.20.20.40.60.60.40.60.60.40.40.40.3
Delta time to tail flick, vehicle, before/after SA0.00.00.10.20.30.20.30.30.1-0.00.1-0.2
Delta time to tail flick, test, before/after SA0.40.40.70.90.80.70.70.70.50.50.40.5
Tibia length2.26.08.8-2.7-2.7-3.0-2.6-2.6-2.6-1.4-2.5-1.4
Ambulatory time before self-admin0.20.20.3-0.4-0.4-0.6-0.6-0.6-0.50.1-0.60.4
Ambulatory time after self-admin1.61.92.6-1.6-1.6-1.6-1.6-1.6-1.3-0.4-1.40.0
Bone: tissue strength3.94.05.0-2.2-2.2-2.1-2.2-2.2-1.8-1.8-1.7-1.5
Total heroin consumption0.00.00.2-0.1-0.1-0.2-0.2-0.2-0.20.3-0.20.4
Bone: trabecular number1.52.53.51.71.71.91.71.71.70.71.70.7
Bone: trabecular spacing3.85.06.3-2.5-2.5-2.5-2.4-2.4-2.4-1.5-2.3-1.3
Bone: trabecular thickness1.21.42.01.41.41.41.41.41.20.71.10.6
Bone: trabecular tissue density2.13.04.4-1.5-1.5-1.6-1.6-1.6-1.8-1.8-2.0-2.1
Water consumed over 24 hours0.00.00.10.00.00.10.10.10.20.20.30.1
Number of responses in last shaping day0.80.91.2-1.0-1.0-1.1-1.0-1.0-1.0-0.5-1.1-0.2