Hub : Genes

LOC134483840

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC134483840 0.51 0.28 1.6e-15 0.15 0.2 0.17 0.18 3.1e-12 7.3e-16 5.2e-14 2.2e-14
2 BLA gene expression LOC134483840 0.33 0.12 2.9e-14 0.24 0.26 0.25 0.26 3.5e-13 2.9e-14 2.2e-13 8.8e-14
3 Adipose gene expression LOC134483840 0.51 0.13 0.0e+00 0.42 0.46 0.45 0.46 2.5e-50 4.2e-56 4.6e-55 2.7e-56
4 NAcc gene expression LOC134483840 0.23 0.11 0.0e+00 0.19 0.2 0.19 0.19 1.5e-28 4.5e-29 4.2e-28 8.9e-28
5 IC gene expression LOC134483840 0.47 0.13 7.9e-15 0.27 0.31 0.28 0.28 7.0e-12 1.2e-13 2.5e-12 2.3e-12
6 PL gene expression LOC134483840 0.36 0.13 0.0e+00 0.32 0.34 0.34 0.34 7.1e-36 2.6e-38 1.2e-37 1.8e-38
7 OFC gene expression LOC134483840 0.48 0.16 3.8e-07 0.23 0.25 0.27 0.29 2.8e-06 1.4e-06 4.8e-07 1.4e-07
8 LHb gene expression LOC134483840 0.53 0.16 5.3e-07 0.2 0.19 0.17 0.2 2.2e-05 3.3e-05 6.2e-05 1.6e-05
9 Brain gene expression LOC134483840 0.35 0.12 0.0e+00 0.31 0.32 0.31 0.32 2.6e-29 3.9e-30 1.4e-29 5.8e-30
10 IL gene expression LOC134483840 0.34 0.15 3.8e-06 0.28 0.24 0.26 0.27 1.4e-07 1.7e-06 5.2e-07 2.9e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.30.8-0.9-0.6-0.9-0.4-0.3-0.4-0.4-0.4-0.1-0.7
Area under the delay curve1.51.82.61.01.41.41.41.41.21.31.21.31.6
BMI with tail0.41.33.2-1.2-0.9-0.8-1.0-0.9-1.1-1.1-1.1-1.2-1.8
BMI without tail0.10.40.70.30.80.80.70.80.50.50.50.4-0.4
Body weight2.510.814.73.53.73.83.53.43.33.33.32.91.6
Weight adjusted by age4.16.36.52.42.52.52.52.52.52.52.62.42.5
Bone surface2.13.94.81.82.01.82.02.12.12.12.12.21.7
Bone volume1.22.13.11.01.41.11.51.71.51.51.51.81.1
Breakpoint value in progressive ratio session4.55.46.6-1.8-2.3-2.1-2.4-2.6-2.4-2.3-2.5-2.6-2.3
Number of licking bursts0.10.20.90.50.30.50.20.10.20.20.20.11.0
Context. condit. distance diff. score0.10.10.20.4-0.2-0.3-0.2-0.5-0.1-0.1-0.1-0.1-0.0
Locomotion velocity, session 10.20.30.30.50.50.50.40.40.60.60.50.60.4
Locomotion distance, session 11.11.41.9-1.4-1.2-1.4-1.2-1.0-1.2-1.1-1.1-1.0-1.4
Locomotion velocity, session 20.50.50.8-0.6-0.6-0.4-0.9-0.9-0.7-0.7-0.8-0.9-0.7
Locomotion distance, session 20.30.40.7-0.7-0.6-0.8-0.6-0.6-0.5-0.5-0.5-0.4-0.8
Locomotion velocity, session 31.51.71.9-1.3-1.3-1.2-1.4-1.3-1.4-1.3-1.4-1.4-1.3
Locomotion distance, session 31.21.31.5-1.1-1.2-1.2-1.2-1.2-1.1-1.1-1.1-1.1-1.0
Stereotopy head waving bouts, day 30.50.61.41.20.91.00.70.60.70.70.60.50.8
Stereotopy head waving duration, day 30.60.71.11.10.91.00.80.70.80.80.70.70.7
Locomotion velocity, session 70.00.10.2-0.4-0.2-0.4-0.1-0.00.10.20.20.3-0.1
Locomotion distance, session 70.40.51.0-0.9-0.8-1.0-0.6-0.5-0.5-0.5-0.5-0.3-0.7
Stereotopy head waving bouts, day 72.73.13.41.51.81.81.81.81.81.81.81.71.7
Stereotopy head waving duration, day 72.42.93.41.51.81.81.71.81.71.71.71.71.7
Locomotion velocity, session 82.52.94.32.11.81.81.61.31.81.71.71.51.6
Locomotion distance, session 80.00.10.20.2-0.3-0.4-0.2-0.5-0.2-0.2-0.2-0.1-0.2
Degree of sensitization distance1.01.01.21.01.00.91.01.01.11.11.11.11.0
Degree of sensitization stereotypy1.21.31.50.81.21.21.11.21.21.21.21.21.1
Conditioned locomotion0.10.10.50.40.50.70.30.30.20.20.20.10.5
Cocaine response after cond. corrected1.41.61.9-1.4-1.2-1.2-1.3-1.3-1.2-1.2-1.2-1.3-1.4
Cocaine response after cond. not corrected0.10.10.30.40.50.50.30.30.40.40.40.30.2
Cocaine response before conditioning11.413.614.33.63.83.83.83.73.73.73.63.63.6
Saline control response0.40.50.90.20.70.70.71.00.60.70.70.80.9
Bone: connectivity density0.10.10.4-0.5-0.4-0.6-0.2-0.1-0.1-0.1-0.10.1-0.3
Bone: cortical apparent density0.20.30.6-0.8-0.5-0.6-0.5-0.3-0.6-0.6-0.6-0.5-0.6
Bone: cortical area1.62.52.81.71.61.51.71.61.61.61.61.61.3
Bone: cortical porosity0.10.10.20.30.30.30.40.40.30.30.30.30.4
Bone: cortical porosity1.21.31.51.11.11.11.21.11.11.11.11.11.2
Bone: cortical thickness0.00.00.1-0.30.1-0.10.10.4-0.00.00.00.1-0.3
Bone: cortical thickness1.41.62.2-1.5-1.2-1.3-1.2-1.0-1.4-1.3-1.3-1.2-1.2
Bone: cortical tissue density0.20.30.6-0.8-0.5-0.5-0.5-0.3-0.6-0.5-0.6-0.5-0.5
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3
Condit. Reinf. active-inactive response ratio0.20.20.3-0.5-0.4-0.4-0.5-0.4-0.5-0.5-0.5-0.5-0.6
Condit. Reinf. active responses0.70.81.0-0.7-0.9-1.0-0.9-0.9-1.0-0.9-1.0-0.9-1.0
Condit. Reinf. inactive responses2.12.63.6-1.4-1.7-1.9-1.5-1.5-1.6-1.6-1.6-1.4-1.7
Incentive salience index mean0.40.40.8-0.1-0.6-0.5-0.7-0.9-0.7-0.7-0.7-0.8-0.6
Condit. Reinf. lever presses1.82.64.1-0.6-1.5-1.4-1.6-2.0-1.6-1.7-1.7-1.8-1.5
Condit. Reinf. active minus inactive responses1.92.52.61.61.61.51.61.61.51.61.51.61.5
Condit. Reinf. active-inactive response ratio2.12.52.91.61.71.71.61.51.51.51.51.51.5
Condit. Reinf. active responses0.30.40.60.70.60.40.60.60.60.60.60.70.6
Condit. Reinf. inactive responses0.30.40.7-0.4-0.7-0.8-0.6-0.6-0.7-0.7-0.7-0.5-0.5
Condit. Reinf. lever presses0.10.10.30.40.2-0.00.30.30.30.30.30.50.5
Condit. Reinf. lever reinforcers received0.20.30.50.70.50.30.50.50.50.50.50.60.5
Conditioned reinforcement - actives0.71.22.20.51.01.11.11.31.01.11.01.21.5
Conditioned reinforcement - inactives0.30.41.10.30.50.50.60.80.50.60.50.71.1
Conditioned locomotion0.81.02.70.80.91.01.01.00.81.00.80.91.6
Patch foraging indifference point 0 sec0.91.63.10.51.20.81.41.71.31.41.41.80.3
Patch foraging indifference point AUC1.72.53.01.61.61.51.61.71.61.61.61.61.3
Delay disc. indifference point, 0s delay0.10.20.30.50.50.60.40.30.40.40.30.20.1
Delay disc. indifference point, 16s delay0.20.20.7-0.30.40.30.50.70.30.40.40.50.9
Delay disc. indifference point, 2s delay1.01.11.71.11.21.31.01.01.01.00.90.91.2
Delay disc. indifference point, 24s delay1.61.82.60.71.31.21.41.61.41.51.41.51.1
Delay disc. indifference point, 4s delay2.22.43.11.51.61.81.51.51.41.51.41.31.8
Delay disc. indifference point, 8s delay1.21.52.30.91.11.11.31.31.11.21.11.21.5
Indifference point function ln k0.00.10.20.40.20.20.20.10.30.30.30.20.5
Indifference point function log k0.00.10.20.40.20.20.20.10.30.30.30.20.5
Patch foraging total patch changes 0 sec1.02.03.60.61.30.91.61.91.41.51.51.90.6
Patch foraging total patch changes 12 sec0.60.81.80.40.80.51.11.30.90.90.91.20.1
Patch foraging total patch changes 18 sec0.40.62.3-0.9-0.6-0.9-0.4-0.1-0.6-0.5-0.5-0.2-1.5
Patch foraging total patch changes 24 sec0.20.30.8-0.70.1-0.30.40.80.40.50.50.9-0.2
Patch foraging total patch changes 6 sec0.71.02.40.21.00.61.21.61.01.01.11.40.2
Patch foraging time to switch 0 sec2.95.96.9-2.5-2.4-2.2-2.4-2.4-2.6-2.6-2.6-2.5-2.1
Patch foraging water rate 0 sec3.06.38.42.02.42.12.62.82.72.82.72.91.9
Patch foraging water rate 12 sec0.00.10.1-0.20.0-0.10.10.30.30.40.30.30.3
Patch foraging water rate 18 sec0.40.61.00.70.80.60.80.80.80.80.80.91.0
Patch foraging water rate 24 sec0.20.30.50.50.60.50.60.60.50.50.50.50.7
Patch foraging water rate 6 sec0.10.10.4-0.4-0.3-0.3-0.3-0.1-0.2-0.2-0.2-0.10.6
Seeking ratio, delayed vs. immediate footshock0.00.10.10.30.30.30.20.30.20.20.10.2-0.2
Distance traveled before self-admin0.20.31.21.10.40.50.40.20.30.20.20.20.8
Distance traveled after self-admin0.20.21.01.00.50.60.40.20.30.40.20.20.4
Extensor digitorum longus weight1.97.49.12.32.62.42.72.82.92.92.93.02.6
Bone: elastic displacement0.00.00.1-0.30.10.20.10.20.10.10.10.10.3
Bone: elastic work0.10.10.20.10.30.40.30.30.20.20.20.10.4
Bone: endosteal estimation5.111.115.23.93.53.73.32.93.33.23.23.03.2
Bone: endosteal perimeter2.75.78.83.02.42.52.32.02.42.32.32.22.3
Epididymis fat weight2.27.416.9-4.1-2.7-2.9-2.5-1.7-2.6-2.4-2.4-2.2-3.1
Delta time in closed arm before/after self-admin0.50.50.70.30.70.70.60.80.80.80.80.80.5
Delta time in open arm before/after self-admin1.21.12.11.41.00.91.11.10.90.90.91.01.5
Diff in mean of infusions in LGA sessions4.75.77.0-2.3-2.6-2.3-2.6-2.6-2.4-2.3-2.4-2.5-1.8
Delay discount exponential model param1.61.82.8-1.0-1.4-1.4-1.4-1.4-1.2-1.3-1.2-1.3-1.7
Extinction: sum of active levers before priming4.95.56.4-1.9-2.4-2.2-2.4-2.5-2.3-2.3-2.4-2.5-2.3
Active lever presses in extinction session 66.16.17.2-2.4-2.5-2.2-2.6-2.6-2.6-2.4-2.6-2.7-2.1
Bone: final force0.40.61.00.60.90.80.91.00.80.80.80.70.3
Bone: final moment1.01.62.31.01.31.21.41.51.31.31.31.30.8
Food consumed during 24 hour testing period0.20.30.90.80.50.80.30.10.40.30.30.10.9
Glucose2.74.25.72.42.02.11.91.52.22.12.12.02.2
Heart weight4.46.98.82.02.72.52.83.02.82.92.92.81.3
Delay discount hyperbolic model param1.41.52.4-0.9-1.3-1.3-1.2-1.3-1.1-1.2-1.1-1.1-1.6
Intermittent access intake day 1-15 change0.00.00.1-0.1-0.2-0.0-0.2-0.2-0.3-0.2-0.3-0.2-0.2
Intermittent access intake escalation0.10.10.2-0.3-0.3-0.1-0.3-0.3-0.5-0.4-0.5-0.4-0.3
Intermittent access intake escalation 20.70.81.31.20.91.00.90.80.70.80.70.81.1
Intermitt. access day 1 inactive lever presses0.00.10.50.70.10.40.1-0.2-0.0-0.0-0.1-0.20.4
Intermitt. access day 15 inactive lever presses1.02.12.91.31.41.61.41.41.41.51.41.41.7
Intermitt. access escalation Index4.66.47.9-2.0-2.5-2.4-2.6-2.8-2.5-2.5-2.5-2.7-2.7
Intermittent access day 1 total infusions0.20.30.7-0.8-0.6-0.6-0.5-0.3-0.5-0.5-0.4-0.4-0.3
Intermittent access day 15 total infusions0.20.30.6-0.8-0.5-0.4-0.6-0.4-0.7-0.6-0.7-0.6-0.4
Intermittent access terminal intake (last 3 days)0.10.10.3-0.20.30.30.30.50.20.20.20.40.5
Intermittent access total infusions0.10.10.3-0.20.20.30.30.50.20.20.20.30.6
Intermittent access day 1 locomotion0.10.20.3-0.3-0.4-0.2-0.5-0.5-0.5-0.5-0.5-0.6-0.1
Intermittent access day 15 total locomotion0.30.61.20.90.91.10.80.70.60.50.50.50.9
Intermittent access total locomotion0.40.51.10.80.81.00.70.70.50.50.50.41.0
Intermittent access standard deviation1.63.34.81.41.81.71.92.11.61.71.71.92.2
Left kidney weight2.712.615.03.53.83.73.73.93.63.73.63.52.1
Right kidney weight3.716.619.54.04.44.34.34.44.14.24.14.02.7
Cocaine induced anxiety0.10.10.60.80.30.40.3-0.00.30.20.30.10.5
Post-drug Anxiety0.30.30.60.0-0.5-0.4-0.6-0.8-0.5-0.5-0.6-0.7-0.0
Baseline Anxiety2.93.34.0-2.0-1.9-2.0-1.9-1.7-1.8-1.7-1.8-1.7-1.7
Tail length5.521.426.85.24.95.04.84.54.64.54.54.33.7
Length with tail9.541.547.56.96.86.86.76.46.66.56.56.24.9
Length without tail4.514.517.54.14.14.23.93.73.93.83.83.52.8
Times rat made contact with spout3.13.64.1-2.0-2.0-2.0-1.9-1.8-1.9-1.9-1.9-1.8-1.6
Lifetime Intake0.20.20.50.00.40.50.50.70.40.50.50.50.7
Liver weight, left1.22.04.92.21.51.71.41.01.41.31.31.01.0
Liver weight, right3.15.49.13.02.52.82.42.02.22.12.11.92.1
Locomotor activity4.77.49.83.12.72.82.72.42.72.72.72.52.7
Locomotor testing distance2.34.15.82.01.92.02.01.82.02.02.02.02.4
Locomotor testing rearing0.91.93.92.01.41.41.51.21.31.31.21.21.0
Locomotion in novel chamber0.40.50.60.50.70.60.80.80.70.70.70.80.5
Locomotion in novel chamber post-restriction0.50.91.00.61.01.00.91.01.01.01.00.90.9
Fecal boli incidents, locomotor time 10.00.00.1-0.3-0.2-0.4-0.1-0.1-0.1-0.1-0.10.1-0.3
Change in fecal boli incidents, locomotor task0.00.00.10.10.20.4-0.0-0.1-0.0-0.1-0.1-0.20.3
Time >=10cm from walls, locomotor time 10.30.30.70.80.60.90.40.30.50.50.40.20.5
Bouts of movement, locomotor time 11.11.21.61.21.00.91.21.11.11.11.11.21.1
Total resting periods, locomotor time 10.80.81.11.10.90.81.00.90.90.90.91.00.9
Rest time, locomotor task time 10.20.20.91.00.60.60.50.30.30.30.30.20.2
Distance moved, locomotor task time 10.50.71.30.30.80.60.81.11.01.01.01.10.5
Vertical activity count, locomotor time 10.20.40.80.20.50.50.50.70.70.70.70.80.9
Time >=10cm from walls, locomotor time 21.21.82.31.21.41.41.31.31.41.51.41.31.0
Bouts of movement, locomotor time 21.01.53.41.81.31.31.31.11.11.01.11.01.1
Total resting periods, locomotor time 21.01.84.02.01.41.41.41.11.21.11.21.11.1
Rest time, locomotor task time 20.10.21.21.10.20.40.2-0.30.1-0.1-0.0-0.20.2
Distance moved, locomotor task time 20.70.91.70.00.80.50.91.31.01.21.11.30.2
Vertical activity count, locomotor time 20.10.10.2-0.20.1-0.00.20.40.20.40.30.4-0.3
Light reinforcement 10.00.00.1-0.30.1-0.20.10.3-0.00.1-0.00.2-0.1
Light reinforcement 22.64.04.91.82.22.02.12.21.92.01.92.11.7
Bone: marrow area4.810.514.63.83.43.63.22.83.23.13.12.93.1
Bone: maximum diameter2.44.56.52.52.12.12.11.92.22.12.12.02.0
Bone: maximum force0.91.52.01.21.41.31.41.41.21.21.21.20.8
Bone: maximum moment1.93.34.01.61.91.82.02.01.91.91.91.81.4
Mean time between licks in bursts0.81.93.71.91.31.51.20.91.21.21.21.11.9
Mean num. licks in bursts0.91.42.4-1.4-1.2-1.4-1.0-0.9-1.1-1.0-1.0-0.9-1.6
Cd content in liver0.20.20.4-0.10.30.10.40.60.40.40.40.60.3
Co content in liver0.00.00.2-0.50.0-0.10.10.30.10.10.10.2-0.2
Cu content in liver1.72.13.0-1.7-1.5-1.7-1.3-1.2-1.4-1.4-1.4-1.2-1.3
Fe content in liver0.40.50.9-1.0-0.7-0.5-0.8-0.6-0.7-0.7-0.7-0.8-0.8
K content in liver0.90.81.0-1.0-1.0-1.0-0.9-0.9-0.9-0.9-0.9-0.9-0.8
Mg content in liver0.10.10.20.0-0.3-0.2-0.3-0.4-0.2-0.3-0.3-0.30.1
Mn content in liver0.10.10.60.70.10.20.0-0.30.10.00.1-0.00.4
Na content in liver0.30.30.6-0.8-0.5-0.5-0.5-0.3-0.5-0.5-0.5-0.4-0.4
Rb content in liver0.10.10.2-0.2-0.3-0.4-0.2-0.2-0.3-0.3-0.2-0.1-0.1
Se content in liver1.11.32.21.51.21.31.10.81.11.11.10.91.3
Sr content in liver0.00.00.20.40.10.20.0-0.2-0.1-0.1-0.1-0.20.2
Zn content in liver0.40.40.60.60.60.50.70.60.70.70.70.70.5
Bone: minimum diameter1.62.95.32.31.71.91.71.31.71.61.61.41.7
Time in familiar zone, hab. session 15.25.06.6-2.6-2.3-2.3-2.2-2.1-2.1-2.2-2.1-2.1-2.2
Time in novel zone, hab. session 110.810.811.53.33.33.13.33.33.33.33.33.43.3
Total zone transitions, hab. session 10.10.10.2-0.5-0.3-0.5-0.3-0.2-0.2-0.2-0.2-0.0-0.3
Total locomotion distance, hab. session 10.30.50.6-0.7-0.7-0.8-0.7-0.6-0.7-0.6-0.7-0.5-0.7
Locomotion velocity, hab. session 10.91.31.4-1.1-1.1-1.2-1.1-1.1-1.2-1.1-1.2-1.0-1.1
Time in familiar zone, hab. session 22.32.42.8-1.5-1.6-1.6-1.6-1.6-1.5-1.5-1.5-1.6-1.7
Time in novel zone, hab. session 23.43.44.11.51.91.71.92.01.91.91.92.01.8
Total zone transitions, hab. session 20.30.40.6-0.8-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.6-0.7
Total locomotion distance, hab. session 20.91.21.6-1.3-1.2-1.2-1.1-1.1-1.1-1.0-1.1-1.0-1.0
Locomotion velocity, hab. session 21.31.71.9-1.3-1.4-1.4-1.3-1.3-1.3-1.3-1.3-1.2-1.2
Novel to familiar place preference ratio0.50.61.00.30.80.60.81.00.70.80.71.00.7
Novelty place preference1.01.01.50.61.00.91.11.21.01.11.01.20.9
Time in novel zone, NPP test1.61.82.40.91.41.21.41.61.31.41.31.51.2
Total zone transitions, NPP test0.10.10.3-0.10.1-0.00.20.30.30.30.30.50.2
Total locomotion distance, NPP test0.20.20.7-0.8-0.6-0.7-0.5-0.3-0.4-0.4-0.4-0.2-0.4
Locomotion velocity, NPP test0.81.11.8-1.3-1.2-1.3-1.1-0.9-1.1-1.0-1.0-0.8-0.9
Intraocular pressure0.00.00.1-0.0-0.0-0.20.10.10.10.10.10.30.1
Delta distance traveled before/after self-admin0.50.50.70.40.80.80.70.90.70.80.70.70.5
Delta ambulatory time before/after self-admin0.20.30.40.40.70.60.60.60.60.60.60.50.2
Parametrial fat weight0.20.50.80.90.90.80.80.80.60.70.60.60.5
Pavlov. Cond. lever latency0.70.91.8-1.3-1.0-1.0-0.8-0.6-0.9-0.9-0.9-0.8-1.0
Pavlov. Cond. magazine entry latency0.81.12.2-0.1-0.9-0.7-1.1-1.5-1.0-1.1-1.1-1.3-0.7
Pavlov. Cond. change in total contacts1.41.52.01.41.31.41.11.01.21.21.11.11.2
Pavlov. Cond. index score0.20.30.90.4-0.3-0.1-0.5-0.9-0.5-0.5-0.6-0.7-0.3
Pavlov. Cond. latency score0.10.10.40.6-0.00.2-0.2-0.6-0.2-0.2-0.3-0.40.0
Pavlov. Cond. lever contacts0.60.71.61.30.91.00.70.50.80.70.70.70.9
Pavlov. Cond. magazine entry number1.92.44.00.71.51.21.62.01.61.71.71.81.2
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.7-0.2-0.5-0.10.3-0.00.10.10.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.20.2-0.5-0.3-0.7-1.1-0.6-0.7-0.7-0.9-0.4
Pavlov. Cond. response bias0.40.51.20.1-0.5-0.3-0.7-1.1-0.7-0.7-0.8-0.9-0.4
Pavlov. Cond. lever latency0.00.00.10.10.00.2-0.1-0.2-0.1-0.1-0.1-0.3-0.2
Pavlov. Cond. magazine entry latency0.20.20.40.60.50.50.40.30.40.40.40.30.5
Pavlov. Cond. change in total contacts0.20.40.60.40.60.50.60.70.60.60.60.70.6
Pavlov. Cond. index score0.30.30.40.50.50.50.60.60.60.60.60.60.6
Pavlov. Cond. latency score0.10.10.20.30.30.30.30.40.30.30.30.40.4
Pavlov. Cond. lever contacts0.10.10.20.10.20.00.30.40.30.30.30.50.4
Pavlov. Cond. magazine entry number0.60.70.8-0.6-0.8-0.8-0.8-0.9-0.9-0.9-0.9-0.9-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.20.4-0.2-0.2-0.2-0.4-0.3-0.3-0.3-0.3-0.1
Pavlov. Cond. lever-magazine prob. diff.0.30.50.60.60.60.50.70.70.70.70.70.80.7
Pavlov. Cond. response bias0.30.40.60.60.60.50.60.70.70.70.70.80.8
Time in closed arm before self-admin0.60.81.0-0.8-0.9-0.7-0.9-0.9-0.9-0.9-0.9-1.0-0.8
Time in closed arm after self-admin0.20.30.7-0.8-0.4-0.2-0.5-0.3-0.5-0.5-0.5-0.5-0.6
Time in open arm before self-admin0.20.20.6-0.3-0.4-0.5-0.4-0.5-0.2-0.3-0.3-0.4-0.8
Time in open arm after self-admin0.10.10.50.70.30.10.30.10.30.30.30.20.1
Bone: periosteal estimation4.59.411.83.43.23.23.12.93.13.03.02.92.8
Bone: periosteal perimeter2.54.46.22.52.12.22.11.92.12.02.12.01.8
Bone: post-yield work2.53.75.72.41.91.81.91.71.91.91.91.91.8
Progressive ratio test 1 active lever presses0.70.81.1-1.0-0.9-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.8
Progressive ratio test 1 breakpoint0.50.70.9-1.0-0.8-0.8-0.8-0.7-0.9-0.8-0.9-0.8-0.7
Progressive ratio test 1 inactive lever presses0.20.31.0-1.0-0.6-0.8-0.5-0.3-0.5-0.4-0.5-0.3-0.1
Progressive ratio test 2 active lever presses1.41.62.2-1.5-1.3-1.1-1.3-1.1-1.3-1.3-1.3-1.3-1.1
Progressive ratio test 2 breakpoint1.61.92.5-1.6-1.4-1.2-1.4-1.2-1.4-1.4-1.4-1.4-1.2
Progressive ratio test 2 inactive lever presses0.10.10.20.20.30.40.30.40.30.30.30.30.4
Incentive Sensitization - Responses1.72.42.5-1.6-1.6-1.4-1.6-1.6-1.6-1.6-1.6-1.6-1.5
Incentive Sensitization - Breakpoint1.92.52.6-1.6-1.6-1.4-1.6-1.6-1.6-1.6-1.6-1.6-1.5
Sum of active levers in priming session hrs 5-60.30.20.4-0.4-0.5-0.5-0.5-0.6-0.5-0.4-0.5-0.5-0.4
Progressive ratio0.00.10.20.40.40.40.20.40.10.10.0-0.0-0.2
Food seeking constrained by brief footshock0.10.10.30.20.40.10.40.40.30.30.30.5-0.1
Seeking ratio, punishment vs. effort0.00.00.2-0.1-0.1-0.20.10.00.20.10.20.40.4
Retroperitoneal fat weight0.52.12.71.31.61.51.61.61.51.51.51.50.7
Reaction time number correct0.10.10.6-0.8-0.1-0.2-0.10.30.00.10.10.2-0.5
Reaction time mean minus median0.82.05.12.31.41.61.30.81.31.11.21.01.5
Reaction time mean minus median AUC0.92.34.52.11.51.61.41.11.41.31.41.21.8
Reaction time num false alarms0.20.20.30.50.50.60.50.40.50.50.50.50.4
Reaction time num false alarms AUC0.30.50.60.70.80.80.70.70.70.70.70.80.5
Reaction time trials correct on left0.10.10.6-0.8-0.1-0.2-0.10.30.00.10.10.2-0.5
Reaction time trials on left0.00.10.5-0.7-0.0-0.10.00.30.10.10.10.2-0.5
Reaction time mean1.52.55.12.31.41.61.40.91.51.31.41.22.2
Reaction time mean AUC1.93.15.72.41.61.81.61.21.71.51.61.42.4
Median of all reaction times1.21.73.91.81.11.31.10.71.21.11.21.02.0
Reaction time omissions0.30.41.61.30.70.90.50.10.50.40.40.30.8
Reaction time false alarm rate0.60.91.51.20.91.00.90.70.90.90.90.81.0
Reaction time premature initiation rate0.30.40.50.40.70.70.60.70.70.70.70.70.6
Reaction time premature initiations0.20.40.6-0.10.60.60.50.80.70.70.70.70.2
Std. dev. reaction times1.83.37.22.71.82.01.71.21.71.51.61.42.1
Reaction time trials completed0.00.10.5-0.7-0.0-0.10.00.30.10.10.10.2-0.5
Reaction time trials AUC0.10.10.5-0.7-0.1-0.2-0.10.20.00.10.10.2-0.5
Run reversals in cocaine runway, females0.10.10.2-0.10.1-0.10.30.40.20.30.30.50.4
Run reversals in cocaine runway, males3.33.45.62.41.92.01.81.61.81.71.71.61.7
Latency to leave start box in cocaine runway0.20.20.3-0.6-0.4-0.2-0.5-0.5-0.5-0.4-0.5-0.6-0.1
Latency to leave start box in cocaine runway, F0.00.00.0-0.2-0.1-0.1-0.1-0.1-0.00.0-0.0-0.00.1
Latency to leave start box in cocaine runway, M0.20.10.4-0.4-0.20.2-0.3-0.4-0.4-0.4-0.5-0.6-0.0
Std. dev. time between licks in bursts1.21.63.61.91.31.41.20.91.21.11.11.01.3
Total sessions with >9 infusions0.00.00.1-0.30.00.20.00.2-0.00.1-0.00.0-0.0
Short access day 1 total inactive lever presses1.31.72.71.61.41.41.31.21.21.21.21.11.3
Short access day 10 total inactive lever presses0.41.11.7-0.5-1.1-1.1-1.1-1.3-1.0-1.1-1.1-1.1-0.8
Short access day 1 total infusions0.20.20.40.20.40.40.50.70.50.60.50.70.4
Short access day 10 total infusions0.10.10.2-0.20.20.30.20.40.20.20.20.30.3
Short access total infusions0.30.40.80.20.60.60.60.90.60.70.70.80.6
Short access day 1 locomotion0.10.10.3-0.6-0.4-0.4-0.3-0.2-0.2-0.2-0.2-0.1-0.3
Short access day 10 total locomotion0.81.52.41.31.21.31.21.11.11.11.11.01.6
Short access total locomotion0.10.10.40.20.20.40.20.20.20.20.20.10.6
One hour access (0.3 mA shock)0.70.81.1-0.9-1.0-1.0-0.9-0.9-0.8-0.8-0.8-0.8-0.7
Compulsive drug intake4.75.68.3-1.7-2.4-2.1-2.5-2.9-2.3-2.4-2.3-2.6-2.3
One hour access (shock baseline)1.42.23.11.01.41.21.51.81.41.51.51.61.6
Social response proportion0.40.51.20.90.60.60.70.60.60.50.60.61.1
Social responses0.00.00.10.30.10.20.10.10.00.00.0-0.00.4
Social time0.30.51.20.7-0.4-0.0-0.6-1.1-0.6-0.7-0.7-1.00.2
Soleus weight2.36.89.63.12.62.72.52.12.62.52.62.42.7
Bone: stiffness0.10.20.9-0.4-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.5-0.9
Tibialis anterior weight0.00.10.8-0.9-0.1-0.2-0.00.30.10.20.20.3-0.1
Time to tail flick, vehicle, before self-admin3.13.24.5-1.0-1.7-1.4-1.8-2.1-1.9-1.9-1.9-2.1-1.7
Time to tail flick, vehicle, after self-admin0.91.22.8-0.5-1.0-1.0-1.0-1.2-0.9-1.0-0.9-1.2-1.7
Time to tail flick, test, before self-admin0.20.20.6-0.4-0.4-0.6-0.3-0.3-0.5-0.5-0.5-0.4-0.8
Time to tail flick, test, after self-admin0.50.50.8-0.1-0.7-0.6-0.8-0.9-0.7-0.8-0.8-0.9-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.10.30.20.50.60.60.60.70.60.1
Delta time to tail flick, test, before/after SA0.60.70.9-0.7-0.9-0.7-0.9-0.9-0.8-0.8-0.8-0.9-0.7
Tibia length1.74.87.52.72.42.62.21.82.12.02.01.72.1
Ambulatory time before self-admin0.00.10.40.70.10.10.1-0.1-0.1-0.1-0.1-0.10.3
Ambulatory time after self-admin0.10.10.40.70.20.20.0-0.2-0.1-0.0-0.1-0.20.1
Bone: tissue strength0.30.30.40.50.60.50.60.60.50.60.60.50.3
Total heroin consumption0.00.10.10.3-0.1-0.2-0.2-0.3-0.2-0.2-0.2-0.3-0.0
Bone: trabecular number0.30.51.3-1.1-0.7-0.9-0.6-0.4-0.6-0.5-0.5-0.3-0.8
Bone: trabecular spacing1.52.02.91.61.51.71.41.31.41.41.31.11.4
Bone: trabecular thickness0.40.61.0-1.0-0.8-1.0-0.7-0.6-0.7-0.7-0.7-0.5-0.6
Bone: trabecular tissue density1.11.62.01.11.31.21.31.41.21.21.21.31.2
Water consumed over 24 hours0.10.10.3-0.1-0.3-0.1-0.4-0.5-0.4-0.4-0.4-0.50.1
Number of responses in last shaping day3.74.05.31.72.11.72.12.32.12.12.12.31.4