Hub : Genes

LOC134482886

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC134482886 0.38 0.2 2.2e-06 0.24 0.16 0.22 0.21 1.5e-06 9.6e-05 4.4e-06 9.5e-06
2 RMTg gene expression LOC134482886 0.18 0.12 1.3e-03 0.07 0.04 0.03 0.04 5.5e-03 4.2e-02 5.5e-02 3.7e-02
3 BLA gene expression LOC134482886 0.3 0.15 1.5e-10 0.14 0.16 0.17 0.16 5.1e-08 6.1e-09 3.0e-09 5.7e-09
4 OFC gene expression LOC134482886 0.32 0.17 2.5e-05 0.08 0.17 0.16 0.16 6.2e-03 7.2e-05 1.6e-04 1.4e-04
5 pVTA gene expression LOC134482886 0.67 0.22 0.0e+00 0.17 0.17 0.18 0.17 1.6e-13 1.0e-13 1.6e-14 1.1e-13
6 NAcc gene expression LOC134482886 0.51 0.18 0.0e+00 0.32 0.37 0.38 0.38 1.8e-49 1.1e-59 1.9e-60 8.7e-62
7 Brain gene expression LOC134482886 0.26 0.13 0.0e+00 0.15 0.21 0.2 0.22 9.2e-14 6.3e-19 6.9e-19 3.6e-20
8 IC gene expression LOC134482886 0.62 0.17 0.0e+00 0.23 0.32 0.32 0.33 3.8e-10 4.6e-14 6.9e-14 1.9e-14
9 PL gene expression LOC134482886 0.42 0.17 0.0e+00 0.18 0.29 0.28 0.3 5.4e-19 9.8e-32 3.8e-30 3.0e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.00.1-0.4-0.3-0.3-0.1-0.1-0.2-0.1-0.1-0.1
Area under the delay curve0.10.20.30.40.60.50.5-0.30.50.30.30.3
BMI with tail0.20.61.81.31.31.10.80.10.5-0.2-0.2-0.1
BMI without tail0.20.61.1-0.4-0.5-0.6-0.9-0.7-0.7-1.0-1.0-0.8
Body weight1.46.18.4-2.5-2.6-2.7-2.9-1.8-2.7-2.2-2.2-2.2
Weight adjusted by age0.20.31.1-1.0-0.9-0.6-0.40.4-0.10.40.40.4
Bone surface2.13.97.2-2.7-2.5-2.5-2.3-1.2-2.0-1.3-1.3-1.2
Bone volume1.73.15.4-2.3-2.2-2.2-2.1-1.1-1.8-1.2-1.2-1.2
Breakpoint value in progressive ratio session0.20.30.50.70.70.70.60.50.50.30.30.3
Number of licking bursts0.00.10.20.30.30.40.30.5-0.10.20.2-0.0
Context. condit. distance diff. score0.40.51.10.40.40.50.61.00.70.70.70.8
Locomotion velocity, session 14.14.48.50.60.41.31.62.92.32.62.62.7
Locomotion distance, session 11.01.32.5-1.5-1.4-0.8-0.41.60.31.11.11.2
Locomotion velocity, session 21.51.72.70.40.50.91.21.61.51.61.61.6
Locomotion distance, session 20.50.72.0-1.4-1.4-1.0-0.80.3-0.30.50.50.4
Locomotion velocity, session 30.30.30.70.10.30.40.50.90.60.60.60.7
Locomotion distance, session 30.40.41.1-0.4-0.30.00.21.10.50.80.80.8
Stereotopy head waving bouts, day 30.10.10.30.50.30.30.10.6-0.0-0.2-0.2-0.2
Stereotopy head waving duration, day 30.10.10.20.50.30.30.00.4-0.1-0.4-0.4-0.3
Locomotion velocity, session 70.30.31.1-0.30.00.20.31.10.20.70.70.6
Locomotion distance, session 70.40.51.1-0.00.20.50.50.90.51.01.00.9
Stereotopy head waving bouts, day 70.30.30.5-0.3-0.5-0.6-0.6-0.0-0.6-0.7-0.7-0.7
Stereotopy head waving duration, day 70.30.40.5-0.4-0.6-0.6-0.6-0.2-0.6-0.7-0.7-0.7
Locomotion velocity, session 81.11.33.20.30.40.70.91.81.11.41.41.4
Locomotion distance, session 80.40.51.4-0.2-0.20.20.21.20.61.01.01.0
Degree of sensitization distance0.00.00.00.00.00.0-0.00.0-0.10.10.1-0.0
Degree of sensitization stereotypy0.20.20.4-0.1-0.3-0.3-0.4-0.2-0.3-0.6-0.6-0.5
Conditioned locomotion0.40.41.0-0.10.00.20.31.00.70.80.80.9
Cocaine response after cond. corrected0.91.02.91.11.20.50.2-1.7-0.4-1.0-1.0-1.1
Cocaine response after cond. not corrected1.11.32.9-0.4-0.4-0.7-0.9-1.7-1.4-1.2-1.2-1.4
Cocaine response before conditioning2.93.48.7-2.8-3.0-2.4-2.20.2-1.8-0.3-0.3-0.5
Saline control response1.01.33.9-0.30.00.30.72.00.91.51.51.4
Bone: connectivity density0.00.00.1-0.10.30.10.3-0.00.10.10.10.1
Bone: cortical apparent density0.30.40.8-0.20.10.20.6-0.20.60.90.90.9
Bone: cortical area0.71.01.9-1.4-1.4-1.2-1.3-0.1-0.9-0.7-0.7-0.6
Bone: cortical porosity0.20.20.60.50.80.50.50.20.3-0.3-0.3-0.1
Bone: cortical porosity0.20.20.60.10.3-0.1-0.1-0.3-0.3-0.8-0.8-0.6
Bone: cortical thickness0.50.81.60.70.70.91.01.30.90.80.80.8
Bone: cortical thickness0.10.10.2-0.2-0.20.00.10.10.20.50.50.4
Bone: cortical tissue density0.20.30.7-0.20.20.20.6-0.30.50.90.90.8
Condit. Reinf. active minus inactive responses0.10.10.30.30.50.30.40.20.20.10.10.1
Condit. Reinf. active-inactive response ratio0.60.61.81.11.31.01.00.10.70.20.20.2
Condit. Reinf. active responses0.10.10.2-0.4-0.3-0.4-0.30.1-0.3-0.1-0.1-0.2
Condit. Reinf. inactive responses1.21.53.8-1.8-1.9-1.6-1.50.3-1.1-0.3-0.3-0.3
Incentive salience index mean0.00.00.1-0.4-0.2-0.4-0.2-0.1-0.2-0.0-0.0-0.1
Condit. Reinf. lever presses0.40.51.1-1.0-1.0-1.0-0.8-0.7-0.6-0.2-0.2-0.2
Condit. Reinf. active minus inactive responses1.92.56.0-2.4-2.4-2.1-2.0-0.4-1.1-0.6-0.6-0.4
Condit. Reinf. active-inactive response ratio4.04.78.1-2.8-2.7-2.7-2.6-1.7-1.9-1.5-1.5-1.3
Condit. Reinf. active responses1.11.54.4-2.1-2.1-1.5-1.40.7-0.50.20.20.3
Condit. Reinf. inactive responses0.60.83.30.10.00.50.51.80.81.01.01.0
Condit. Reinf. lever presses1.01.42.0-1.0-1.0-1.1-1.4-0.7-1.2-1.4-1.4-1.2
Condit. Reinf. lever reinforcers received1.42.05.7-2.4-2.3-1.8-1.60.6-0.70.10.10.2
Conditioned reinforcement - actives0.50.91.8-0.7-0.7-1.0-1.0-1.4-0.6-1.0-1.0-0.8
Conditioned reinforcement - inactives1.01.52.9-1.6-1.7-1.7-1.5-1.0-0.7-0.5-0.5-0.3
Conditioned locomotion0.30.41.4-0.5-0.5-0.6-0.7-1.2-0.3-0.7-0.7-0.5
Patch foraging indifference point 0 sec0.71.43.00.60.91.01.11.71.41.11.11.2
Patch foraging indifference point AUC0.40.51.31.21.11.00.90.30.60.30.30.2
Delay disc. indifference point, 0s delay0.70.81.50.20.30.60.71.21.01.11.11.1
Delay disc. indifference point, 16s delay0.40.51.80.60.60.20.0-1.3-0.3-0.8-0.8-0.8
Delay disc. indifference point, 2s delay0.50.61.00.60.80.80.90.11.00.80.80.8
Delay disc. indifference point, 24s delay0.20.31.10.50.70.40.4-1.10.1-0.3-0.3-0.2
Delay disc. indifference point, 4s delay0.20.20.5-0.5-0.4-0.5-0.4-0.7-0.3-0.3-0.3-0.3
Delay disc. indifference point, 8s delay0.10.10.20.30.30.30.40.00.40.30.30.3
Indifference point function ln k1.93.39.2-3.0-3.0-2.4-2.20.0-1.1-0.2-0.2-0.0
Indifference point function log k1.93.39.2-3.0-3.0-2.4-2.20.0-1.1-0.2-0.2-0.0
Patch foraging total patch changes 0 sec0.61.22.50.60.81.01.01.61.31.01.01.2
Patch foraging total patch changes 12 sec0.10.10.50.50.70.50.40.10.3-0.0-0.00.0
Patch foraging total patch changes 18 sec0.40.61.50.80.90.90.91.20.70.50.50.5
Patch foraging total patch changes 24 sec0.20.31.0-0.20.1-0.2-0.3-1.0-0.5-0.8-0.8-0.7
Patch foraging total patch changes 6 sec0.50.81.61.21.31.11.00.71.00.30.30.4
Patch foraging time to switch 0 sec1.32.75.51.51.50.40.1-2.3-1.2-2.0-2.0-2.1
Patch foraging water rate 0 sec0.40.81.5-0.7-0.7-0.10.01.20.71.11.11.2
Patch foraging water rate 12 sec0.81.62.7-1.6-1.7-0.8-0.51.60.31.41.41.3
Patch foraging water rate 18 sec0.60.91.6-1.0-0.9-0.3-0.21.30.61.11.11.2
Patch foraging water rate 24 sec0.40.61.3-1.0-0.9-0.5-0.31.10.40.70.70.9
Patch foraging water rate 6 sec3.14.610.2-3.2-3.1-2.8-2.6-0.7-1.8-0.9-0.9-0.9
Seeking ratio, delayed vs. immediate footshock0.91.12.90.20.10.50.71.71.01.31.31.3
Distance traveled before self-admin1.11.42.9-1.3-1.1-0.4-0.11.70.61.41.41.4
Distance traveled after self-admin1.92.34.30.60.81.21.42.11.61.81.81.8
Extensor digitorum longus weight0.41.72.3-1.2-1.2-1.2-1.5-1.1-1.5-1.3-1.3-1.3
Bone: elastic displacement1.21.43.81.11.01.21.12.01.20.90.91.0
Bone: elastic work0.20.20.9-0.4-0.7-0.3-0.31.00.10.20.20.3
Bone: endosteal estimation2.86.29.3-2.8-2.9-2.9-3.1-2.0-2.5-2.0-2.0-1.9
Bone: endosteal perimeter1.53.25.3-2.3-2.3-2.1-2.3-0.9-1.7-1.3-1.3-1.2
Epididymis fat weight0.51.83.50.0-0.3-0.7-1.0-1.9-1.4-1.8-1.8-1.8
Delta time in closed arm before/after self-admin0.10.10.20.50.30.30.3-0.10.30.20.20.2
Delta time in open arm before/after self-admin0.60.61.5-1.2-1.2-1.0-0.80.7-0.50.00.00.0
Diff in mean of infusions in LGA sessions0.40.51.3-0.1-0.00.20.41.10.70.90.90.9
Delay discount exponential model param0.10.10.2-0.3-0.4-0.3-0.40.4-0.4-0.2-0.2-0.2
Extinction: sum of active levers before priming0.30.40.50.40.50.60.70.60.70.70.70.7
Active lever presses in extinction session 61.21.23.4-0.0-0.1-0.5-0.7-1.8-1.0-1.3-1.3-1.3
Bone: final force1.52.44.4-2.0-2.1-1.9-1.9-1.2-1.4-0.9-0.9-0.9
Bone: final moment1.72.75.5-2.3-2.3-2.1-2.1-1.0-1.4-0.9-0.9-0.8
Food consumed during 24 hour testing period1.11.52.7-1.7-1.6-1.4-1.5-0.3-1.3-0.7-0.7-0.8
Glucose1.72.73.51.81.71.91.91.41.71.41.41.4
Heart weight1.93.04.2-1.9-1.7-1.9-1.9-1.5-2.1-1.5-1.5-1.6
Delay discount hyperbolic model param0.10.20.3-0.3-0.5-0.4-0.50.3-0.5-0.3-0.3-0.3
Intermittent access intake day 1-15 change0.40.81.1-1.0-1.0-1.1-1.0-0.8-1.0-0.5-0.5-0.6
Intermittent access intake escalation0.71.42.1-1.3-1.3-1.4-1.4-1.2-1.4-0.9-0.9-0.9
Intermittent access intake escalation 20.10.10.3-0.2-0.2-0.10.10.4-0.10.60.60.4
Intermitt. access day 1 inactive lever presses0.51.92.6-1.4-1.5-1.6-1.6-1.4-1.3-1.2-1.2-1.1
Intermitt. access day 15 inactive lever presses1.73.54.9-1.9-2.0-2.2-2.2-2.0-1.6-1.7-1.7-1.4
Intermitt. access escalation Index0.20.30.60.80.80.60.6-0.40.50.20.20.2
Intermittent access day 1 total infusions0.50.81.4-0.9-1.0-1.0-1.1-1.2-0.4-0.9-0.9-0.6
Intermittent access day 15 total infusions1.31.93.5-1.3-1.3-1.5-1.6-1.9-1.0-1.3-1.3-1.0
Intermittent access terminal intake (last 3 days)1.01.42.6-1.2-1.2-1.3-1.3-1.6-0.8-1.0-1.0-0.7
Intermittent access total infusions1.61.93.0-1.5-1.5-1.6-1.6-1.7-0.9-1.2-1.2-0.9
Intermittent access day 1 locomotion1.11.42.8-1.3-1.3-1.4-1.4-1.7-0.7-1.0-1.0-0.6
Intermittent access day 15 total locomotion0.40.71.9-1.3-1.4-1.1-1.0-0.2-0.1-0.0-0.00.3
Intermittent access total locomotion2.42.84.7-2.1-2.2-2.1-2.0-1.8-1.3-1.1-1.1-0.8
Intermittent access standard deviation0.10.20.30.40.50.60.50.10.40.40.40.4
Left kidney weight3.817.830.4-5.5-5.5-5.3-5.1-2.2-4.2-2.8-2.8-2.7
Right kidney weight4.420.030.2-5.3-5.5-5.4-5.4-2.7-4.6-3.4-3.4-3.3
Cocaine induced anxiety0.60.91.6-1.3-1.2-1.2-1.1-0.2-1.0-0.5-0.5-0.6
Post-drug Anxiety0.70.81.1-0.9-0.8-1.0-1.0-0.6-1.1-0.9-0.9-0.9
Baseline Anxiety0.30.41.11.00.90.90.70.10.40.20.20.2
Tail length2.38.815.4-3.9-3.9-3.8-3.6-1.7-2.9-1.8-1.8-1.8
Length with tail2.912.618.2-4.2-4.2-4.3-4.2-2.6-3.8-2.7-2.7-2.7
Length without tail2.78.812.5-2.7-2.7-3.1-3.2-2.8-3.5-2.8-2.8-3.0
Times rat made contact with spout0.00.00.10.00.20.1-0.0-0.0-0.1-0.4-0.4-0.3
Lifetime Intake1.11.32.3-1.2-1.2-1.3-1.4-1.5-0.7-1.0-1.0-0.8
Liver weight, left1.01.72.6-1.4-1.6-1.5-1.5-0.8-1.5-1.0-1.0-1.1
Liver weight, right0.00.10.1-0.1-0.2-0.2-0.3-0.1-0.3-0.3-0.3-0.3
Locomotor activity0.10.10.10.40.20.1-0.0-0.4-0.1-0.4-0.4-0.3
Locomotor testing distance0.50.92.0-0.2-0.4-0.7-0.8-1.4-1.0-1.1-1.1-1.1
Locomotor testing rearing0.71.31.6-1.0-1.1-1.3-1.2-1.3-1.1-1.2-1.2-1.1
Locomotion in novel chamber0.50.61.21.01.11.11.00.40.70.50.50.4
Locomotion in novel chamber post-restriction0.10.20.60.80.80.60.5-0.40.3-0.0-0.0-0.0
Fecal boli incidents, locomotor time 10.10.10.3-0.6-0.5-0.5-0.4-0.2-0.5-0.0-0.0-0.1
Change in fecal boli incidents, locomotor task2.42.33.81.91.91.91.80.81.61.11.11.1
Time >=10cm from walls, locomotor time 10.00.00.10.20.20.00.0-0.3-0.3-0.2-0.2-0.3
Bouts of movement, locomotor time 10.91.03.3-0.1-0.10.30.51.80.81.31.31.3
Total resting periods, locomotor time 10.70.82.00.20.40.60.71.40.91.11.11.1
Rest time, locomotor task time 10.81.01.6-1.3-1.0-1.3-1.2-1.0-1.2-0.6-0.6-0.7
Distance moved, locomotor task time 10.81.21.81.31.21.31.21.11.30.70.70.8
Vertical activity count, locomotor time 11.94.66.52.01.92.32.32.52.51.91.92.0
Time >=10cm from walls, locomotor time 20.30.41.11.01.00.80.8-0.10.30.10.10.0
Bouts of movement, locomotor time 20.00.00.1-0.1-0.2-0.1-0.1-0.2-0.2-0.1-0.1-0.1
Total resting periods, locomotor time 20.00.00.0-0.1-0.2-0.1-0.1-0.1-0.00.10.10.0
Rest time, locomotor task time 20.10.20.40.00.00.20.30.50.40.60.60.5
Distance moved, locomotor task time 20.20.20.40.50.40.50.40.50.60.20.20.4
Vertical activity count, locomotor time 20.20.30.70.40.30.60.50.80.80.50.50.6
Light reinforcement 10.92.14.30.20.50.91.22.11.31.91.91.7
Light reinforcement 21.72.63.31.61.71.81.81.51.61.51.51.4
Bone: marrow area2.96.49.5-2.8-3.0-2.9-3.1-2.0-2.6-2.0-2.0-1.9
Bone: maximum diameter1.32.43.7-1.7-1.7-1.7-1.9-0.8-1.7-1.4-1.4-1.4
Bone: maximum force2.54.47.1-2.6-2.7-2.5-2.6-1.3-2.0-1.5-1.5-1.5
Bone: maximum moment2.64.68.1-2.8-2.9-2.6-2.7-1.1-2.0-1.4-1.4-1.3
Mean time between licks in bursts0.51.31.61.21.01.31.21.11.31.11.11.1
Mean num. licks in bursts0.30.40.7-0.6-0.4-0.6-0.7-0.8-0.4-0.7-0.7-0.5
Cd content in liver1.01.12.9-1.7-1.6-1.4-1.3-0.6-0.9-0.2-0.2-0.3
Co content in liver0.40.51.0-1.0-0.7-0.50.00.40.40.90.91.0
Cu content in liver0.70.91.9-1.4-1.0-1.2-0.9-0.8-1.0-0.6-0.6-0.6
Fe content in liver0.20.20.6-0.8-0.6-0.6-0.5-0.3-0.3-0.3-0.3-0.2
K content in liver0.00.00.10.00.10.00.10.3-0.20.10.1-0.0
Mg content in liver0.20.20.40.10.2-0.1-0.1-0.5-0.5-0.7-0.7-0.7
Mn content in liver0.20.20.5-0.10.0-0.4-0.2-0.3-0.6-0.7-0.7-0.7
Na content in liver2.02.14.01.72.01.81.91.41.40.80.80.8
Rb content in liver2.22.63.7-1.9-1.8-1.9-1.9-0.8-1.7-1.4-1.4-1.3
Se content in liver0.60.82.21.41.51.20.90.20.4-0.3-0.3-0.3
Sr content in liver7.66.68.32.52.62.92.82.62.82.22.22.2
Zn content in liver0.50.61.80.40.60.20.0-1.3-0.5-0.9-0.9-0.9
Bone: minimum diameter2.44.47.9-2.7-2.8-2.6-2.6-0.7-2.1-1.4-1.4-1.3
Time in familiar zone, hab. session 11.21.13.7-1.9-1.8-1.2-1.00.1-0.50.50.50.4
Time in novel zone, hab. session 11.41.43.21.81.71.61.41.01.00.30.30.3
Total zone transitions, hab. session 11.31.83.5-0.7-0.60.10.51.91.21.81.81.9
Total locomotion distance, hab. session 11.01.42.7-0.3-0.20.40.71.61.21.61.61.6
Locomotion velocity, hab. session 10.70.91.8-0.2-0.10.30.61.21.01.31.31.4
Time in familiar zone, hab. session 24.14.45.4-2.0-2.0-2.3-2.3-2.2-2.3-1.8-1.8-1.9
Time in novel zone, hab. session 22.12.13.01.61.61.71.71.51.51.11.11.1
Total zone transitions, hab. session 20.81.02.5-1.6-1.6-1.0-0.81.0-0.10.60.60.6
Total locomotion distance, hab. session 20.60.81.8-0.00.00.50.61.30.91.21.21.2
Locomotion velocity, hab. session 20.91.22.50.10.20.70.81.61.21.41.41.4
Novel to familiar place preference ratio0.10.10.2-0.2-0.2-0.3-0.3-0.3-0.3-0.4-0.4-0.4
Novelty place preference0.10.20.2-0.4-0.4-0.4-0.5-0.2-0.4-0.4-0.4-0.4
Time in novel zone, NPP test0.20.20.3-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.5
Total zone transitions, NPP test0.20.30.7-0.5-0.5-0.10.00.80.40.70.70.8
Total locomotion distance, NPP test0.10.20.4-0.6-0.6-0.5-0.50.3-0.3-0.1-0.1-0.0
Locomotion velocity, NPP test0.10.20.5-0.6-0.6-0.4-0.30.7-0.00.30.30.3
Intraocular pressure0.20.20.40.30.30.40.50.70.50.60.60.5
Delta distance traveled before/after self-admin1.01.12.41.41.61.31.30.60.90.40.40.4
Delta ambulatory time before/after self-admin0.81.02.01.31.41.31.20.70.90.50.50.5
Parametrial fat weight0.81.95.02.22.01.81.50.31.40.20.20.4
Pavlov. Cond. lever latency0.20.30.60.20.50.60.50.80.40.50.50.5
Pavlov. Cond. magazine entry latency0.30.41.01.00.90.60.4-0.7-0.1-0.3-0.3-0.5
Pavlov. Cond. change in total contacts0.10.10.30.50.50.40.5-0.10.40.30.30.2
Pavlov. Cond. index score0.10.10.40.60.50.40.4-0.50.10.00.0-0.1
Pavlov. Cond. latency score0.10.10.50.50.40.20.3-0.70.0-0.1-0.1-0.2
Pavlov. Cond. lever contacts0.60.71.3-0.3-0.5-0.8-0.8-1.2-0.8-0.9-0.9-0.9
Pavlov. Cond. magazine entry number0.10.20.5-0.5-0.5-0.3-0.20.70.20.30.30.4
Pavlov. Cond. intertrial magazine entries2.02.56.90.30.30.91.22.61.71.81.81.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.60.50.40.4-0.50.0-0.0-0.0-0.1
Pavlov. Cond. response bias0.40.51.50.0-0.0-0.3-0.4-1.2-0.7-0.8-0.8-0.9
Pavlov. Cond. lever latency0.30.40.9-0.8-0.7-0.8-0.5-1.0-0.9-0.2-0.2-0.4
Pavlov. Cond. magazine entry latency0.40.51.61.31.10.80.50.20.4-0.2-0.2-0.1
Pavlov. Cond. change in total contacts0.10.21.1-0.3-0.4-0.1-0.21.10.50.20.20.4
Pavlov. Cond. index score0.10.10.20.40.30.3-0.00.40.3-0.3-0.3-0.1
Pavlov. Cond. latency score0.20.30.80.90.70.70.30.50.5-0.2-0.2-0.0
Pavlov. Cond. lever contacts0.10.20.60.50.30.50.20.80.5-0.0-0.00.2
Pavlov. Cond. magazine entry number0.20.30.8-0.9-0.8-0.7-0.4-0.1-0.50.10.1-0.1
Pavlov. Cond. intertrial magazine entries1.32.05.0-2.2-2.2-1.8-1.7-0.4-1.3-0.3-0.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.60.40.50.10.40.5-0.1-0.10.1
Pavlov. Cond. response bias0.10.10.3-0.1-0.3-0.1-0.40.50.1-0.3-0.3-0.0
Time in closed arm before self-admin0.50.61.5-1.2-1.0-1.0-0.9-0.0-0.8-0.4-0.4-0.4
Time in closed arm after self-admin0.20.30.3-0.4-0.3-0.5-0.5-0.5-0.6-0.6-0.6-0.6
Time in open arm before self-admin1.21.33.01.71.61.51.40.31.10.50.50.5
Time in open arm after self-admin0.40.50.70.70.50.70.70.90.80.70.70.7
Bone: periosteal estimation2.04.16.6-2.5-2.6-2.4-2.6-1.1-2.0-1.5-1.5-1.4
Bone: periosteal perimeter1.22.14.2-2.0-2.0-1.8-1.9-0.3-1.3-0.9-0.9-0.8
Bone: post-yield work3.95.87.5-2.7-2.5-2.7-2.7-2.0-2.5-2.1-2.1-2.0
Progressive ratio test 1 active lever presses0.20.30.7-0.8-0.8-0.6-0.50.40.20.20.20.4
Progressive ratio test 1 breakpoint0.20.30.7-0.8-0.8-0.6-0.50.40.20.20.20.4
Progressive ratio test 1 inactive lever presses1.11.73.6-1.8-1.9-1.8-1.6-0.8-0.7-0.6-0.6-0.4
Progressive ratio test 2 active lever presses1.01.21.7-0.9-1.0-1.2-1.2-1.3-0.9-1.2-1.2-1.0
Progressive ratio test 2 breakpoint1.31.41.8-1.0-1.1-1.3-1.4-1.4-1.0-1.3-1.3-1.0
Progressive ratio test 2 inactive lever presses1.72.85.1-2.2-2.3-2.2-2.1-1.2-1.2-1.1-1.1-0.8
Incentive Sensitization - Responses2.33.24.1-1.6-1.6-2.0-2.0-1.9-1.7-1.8-1.8-1.6
Incentive Sensitization - Breakpoint2.12.73.5-1.3-1.4-1.8-1.8-1.9-1.6-1.7-1.7-1.6
Sum of active levers in priming session hrs 5-60.30.30.40.10.30.40.50.70.60.70.70.7
Progressive ratio0.30.51.60.20.20.50.51.30.50.80.80.7
Food seeking constrained by brief footshock6.17.519.50.60.51.62.04.42.63.43.43.3
Seeking ratio, punishment vs. effort0.20.20.5-0.7-0.7-0.4-0.20.50.10.50.50.5
Retroperitoneal fat weight1.46.118.44.34.03.32.6-0.71.6-0.3-0.3-0.2
Reaction time number correct0.30.51.50.70.50.70.60.41.20.60.60.9
Reaction time mean minus median0.10.31.3-0.1-0.2-0.3-0.3-1.2-0.6-0.3-0.3-0.5
Reaction time mean minus median AUC0.10.31.30.1-0.1-0.3-0.3-1.2-0.7-0.5-0.5-0.6
Reaction time num false alarms0.00.00.1-0.4-0.1-0.1-0.1-0.2-0.0-0.1-0.1-0.0
Reaction time num false alarms AUC0.20.30.50.20.40.50.70.60.60.70.70.7
Reaction time trials correct on left0.30.51.50.70.50.70.60.41.20.60.60.9
Reaction time trials on left0.30.51.50.70.50.70.60.41.20.60.60.9
Reaction time mean1.32.13.7-1.2-1.2-1.5-1.5-1.9-1.7-1.2-1.2-1.4
Reaction time mean AUC1.11.84.3-0.8-0.9-1.2-1.2-2.1-1.6-1.3-1.3-1.4
Median of all reaction times1.31.93.0-1.2-1.2-1.4-1.4-1.7-1.6-1.2-1.2-1.3
Reaction time omissions0.20.30.60.10.20.40.50.60.50.80.80.7
Reaction time false alarm rate0.10.10.3-0.20.10.20.40.50.10.40.40.3
Reaction time premature initiation rate0.30.40.9-0.7-0.2-0.4-0.3-0.9-0.9-0.7-0.7-0.8
Reaction time premature initiations0.10.20.6-0.20.1-0.0-0.0-0.8-0.4-0.5-0.5-0.5
Std. dev. reaction times0.91.73.8-1.0-1.0-1.3-1.2-2.0-1.5-1.1-1.1-1.2
Reaction time trials completed0.30.51.50.70.50.70.60.41.20.60.60.9
Reaction time trials AUC0.20.31.00.50.40.60.40.11.00.30.30.6
Run reversals in cocaine runway, females0.70.70.8-0.8-0.7-0.9-0.9-0.9-0.9-0.9-0.9-0.8
Run reversals in cocaine runway, males0.10.10.2-0.1-0.2-0.3-0.3-0.4-0.1-0.4-0.4-0.2
Latency to leave start box in cocaine runway0.20.30.6-0.5-0.8-0.5-0.6-0.7-0.6-0.2-0.2-0.3
Latency to leave start box in cocaine runway, F0.10.10.30.0-0.2-0.0-0.1-0.6-0.3-0.0-0.0-0.2
Latency to leave start box in cocaine runway, M1.01.01.7-1.3-1.3-1.3-1.2-0.7-1.0-0.6-0.6-0.6
Std. dev. time between licks in bursts1.92.65.30.70.51.21.42.31.52.02.01.9
Total sessions with >9 infusions0.50.61.3-1.1-1.1-1.1-0.9-0.5-0.4-0.3-0.3-0.2
Short access day 1 total inactive lever presses1.31.72.3-1.2-1.2-1.4-1.4-1.5-1.2-1.3-1.3-1.2
Short access day 10 total inactive lever presses0.10.20.4-0.5-0.5-0.5-0.5-0.6-0.3-0.3-0.3-0.3
Short access day 1 total infusions0.00.00.1-0.0-0.0-0.1-0.1-0.20.4-0.0-0.00.2
Short access day 10 total infusions0.10.10.40.10.10.20.1-0.10.60.10.10.4
Short access total infusions0.10.10.20.30.20.20.2-0.50.50.00.00.2
Short access day 1 locomotion0.81.02.1-0.8-0.8-1.1-1.0-1.4-1.1-0.9-0.9-0.9
Short access day 10 total locomotion0.20.40.7-0.8-0.8-0.4-0.30.50.50.70.70.8
Short access total locomotion0.30.30.8-0.3-0.4-0.10.10.40.60.80.80.9
One hour access (0.3 mA shock)3.33.86.2-2.4-2.4-2.5-2.4-1.7-1.6-1.5-1.5-1.2
Compulsive drug intake1.01.22.4-1.5-1.6-1.5-1.5-0.3-0.4-0.8-0.8-0.4
One hour access (shock baseline)0.71.13.1-0.7-0.7-0.9-1.0-1.8-0.9-1.1-1.1-1.0
Social response proportion1.71.93.4-1.3-1.1-1.4-1.4-1.8-1.2-1.4-1.4-1.2
Social responses2.02.64.9-2.2-2.0-2.0-1.9-0.9-1.6-1.0-1.0-1.0
Social time1.11.54.6-2.2-2.0-1.4-1.00.8-0.20.50.50.6
Soleus weight0.10.30.4-0.5-0.3-0.5-0.5-0.6-0.6-0.4-0.4-0.5
Bone: stiffness2.13.45.4-2.3-2.3-2.2-2.2-1.3-1.8-1.3-1.3-1.2
Tibialis anterior weight0.20.71.61.31.31.00.4-0.60.0-0.7-0.7-0.7
Time to tail flick, vehicle, before self-admin0.20.20.7-0.4-0.5-0.2-0.10.80.20.50.50.5
Time to tail flick, vehicle, after self-admin0.91.23.2-1.0-0.7-1.0-1.0-1.8-1.1-0.9-0.9-0.9
Time to tail flick, test, before self-admin1.41.42.70.30.40.81.01.71.31.51.51.5
Time to tail flick, test, after self-admin0.10.10.30.40.50.40.3-0.10.1-0.1-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.80.83.6-0.2-0.1-0.4-0.5-1.9-0.7-0.9-0.9-0.9
Delta time to tail flick, test, before/after SA0.70.71.1-0.3-0.3-0.6-0.7-1.0-0.9-1.0-1.0-1.0
Tibia length3.08.312.0-3.5-3.5-3.4-3.5-1.8-2.9-2.3-2.3-2.2
Ambulatory time before self-admin0.61.01.9-1.4-1.1-0.6-0.31.30.31.01.01.0
Ambulatory time after self-admin1.31.54.2-0.10.10.60.82.01.21.51.51.5
Bone: tissue strength0.60.61.3-0.3-0.30.10.30.70.71.11.11.1
Total heroin consumption0.10.20.20.30.30.40.40.50.40.40.40.4
Bone: trabecular number0.10.20.40.40.50.50.70.20.50.40.40.4
Bone: trabecular spacing0.00.10.10.2-0.1-0.1-0.3-0.0-0.3-0.3-0.3-0.3
Bone: trabecular thickness0.00.10.2-0.1-0.0-0.1-0.1-0.5-0.1-0.3-0.3-0.2
Bone: trabecular tissue density0.30.51.11.01.00.60.4-0.6-0.2-0.6-0.6-0.7
Water consumed over 24 hours0.30.41.5-1.2-1.1-0.7-0.70.3-0.40.10.10.0
Number of responses in last shaping day0.50.52.1-0.1-0.1-0.3-0.4-1.4-0.9-0.6-0.6-0.8