Hub : Genes

LOC134481857

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC134481857 0.23 0.1 0.0e+00 0.25 0.3 0.28 0.3 1.3e-13 4.2e-16 4.4e-15 5.0e-16
2 Brain gene expression LOC134481857 0.11 0.06 1.5e-13 0.15 0.15 0.15 0.15 1.4e-13 4.8e-14 9.4e-14 1.3e-13
3 NAcc gene expression LOC134481857 0.09 0.05 5.6e-17 0.12 0.12 0.11 0.12 4.0e-17 3.0e-17 1.1e-16 5.0e-17
4 RMTg gene expression LOC134481857 0.31 0.21 9.2e-05 0.14 0.12 0.16 0.13 1.2e-04 5.7e-04 3.8e-05 2.1e-04
5 pVTA gene expression LOC134481857 0.2 0.09 0.0e+00 0.27 0.26 0.27 0.26 5.8e-22 3.2e-21 1.8e-21 2.4e-21
6 Adipose mRNA stability LOC134481857 0.04 0.03 5.8e-05 0.03 0.03 0.03 0.03 1.1e-04 1.1e-04 1.2e-04 1.2e-04
7 PL gene expression LOC134481857 0.18 0.08 0.0e+00 0.23 0.24 0.23 0.24 4.4e-25 7.0e-26 1.6e-24 2.1e-26
8 Adipose gene expression LOC134481857 0.03 0.02 9.0e-05 0.03 0.03 0.03 0.03 1.1e-04 2.4e-04 4.0e-04 2.5e-04
9 IC gene expression LOC134481857 0.15 0.08 4.2e-07 0.17 0.16 0.15 0.16 1.4e-07 4.8e-07 6.0e-07 3.3e-07
10 OFC gene expression LOC134481857 0.11 0.07 4.0e-03 0.09 0.08 0.04 0.06 4.3e-03 6.3e-03 4.5e-02 1.5e-02
11 LHb gene expression LOC134481857 0.25 0.14 3.2e-03 0.01 -0 0.02 0.01 1.6e-01 3.7e-01 1.0e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.81.32.9-1.0-1.0-0.8-1.7-1.31.4-1.5-1.0-0.9-1.1-0.6
Area under the delay curve0.30.31.20.50.30.50.20.6-0.40.70.60.50.41.1
BMI with tail1.34.410.52.51.92.21.43.0-3.21.91.71.61.60.9
BMI without tail0.82.36.91.81.31.41.12.4-2.61.41.00.91.00.0
Body weight5.925.729.85.45.25.15.05.4-5.55.34.95.04.74.1
Weight adjusted by age2.53.94.42.02.01.92.02.0-2.02.11.82.11.81.9
Bone surface0.30.61.10.70.80.80.60.3-0.10.91.01.10.91.0
Bone volume0.00.00.20.00.00.2-0.4-0.30.3-0.20.10.2-0.00.1
Breakpoint value in progressive ratio session0.10.10.4-0.3-0.4-0.3-0.4-0.30.1-0.6-0.3-0.6-0.3-0.2
Number of licking bursts1.62.64.11.81.92.01.11.0-1.21.21.91.71.91.7
Context. condit. distance diff. score0.30.40.8-0.8-0.8-0.9-0.2-0.40.5-0.6-0.3-0.9-0.3-0.5
Locomotion velocity, session 11.21.32.0-1.4-1.3-1.4-0.5-1.11.2-1.0-1.1-1.2-1.1-0.8
Locomotion distance, session 10.40.50.9-0.7-0.7-0.6-0.9-0.80.8-0.8-0.8-0.7-0.8-0.1
Locomotion velocity, session 24.24.98.3-2.6-2.2-2.4-1.4-2.92.8-2.2-1.9-2.1-2.0-1.0
Locomotion distance, session 22.53.55.1-2.1-2.0-2.0-1.8-2.32.2-1.6-1.8-1.8-1.9-0.4
Locomotion velocity, session 30.20.20.6-0.5-0.4-0.50.5-0.60.60.30.1-0.10.10.8
Locomotion distance, session 30.20.21.2-0.3-0.2-0.51.10.0-0.10.70.30.00.30.3
Stereotopy head waving bouts, day 32.63.15.8-1.4-1.7-1.6-1.9-1.10.6-2.3-1.7-2.1-1.7-2.4
Stereotopy head waving duration, day 32.32.85.7-1.3-1.6-1.5-1.9-1.00.5-2.1-1.7-1.9-1.7-2.4
Locomotion velocity, session 72.83.18.01.11.61.32.40.2-0.61.82.11.62.02.8
Locomotion distance, session 70.50.63.5-0.3-0.1-0.20.9-0.70.70.50.60.20.61.9
Stereotopy head waving bouts, day 70.40.42.20.70.30.40.41.1-1.50.30.40.10.3-0.2
Stereotopy head waving duration, day 71.21.43.61.41.01.10.81.7-1.90.91.10.91.00.4
Locomotion velocity, session 81.01.22.5-1.4-1.1-1.3-0.4-1.51.6-1.0-0.8-1.0-0.9-0.5
Locomotion distance, session 81.92.84.1-2.0-1.9-2.0-1.1-1.81.8-1.7-1.3-1.9-1.4-0.9
Degree of sensitization distance0.50.51.6-0.6-0.4-0.3-0.6-1.21.3-0.9-0.3-0.4-0.30.6
Degree of sensitization stereotypy1.31.43.01.31.01.11.01.6-1.71.11.00.91.00.6
Conditioned locomotion0.50.51.90.60.50.70.10.4-0.10.90.80.80.81.4
Cocaine response after cond. corrected2.12.53.3-1.5-1.7-1.6-1.8-1.41.2-1.7-1.6-1.8-1.5-1.5
Cocaine response after cond. not corrected0.91.11.5-1.0-1.1-1.0-1.2-1.00.7-1.2-1.0-1.2-1.0-0.7
Cocaine response before conditioning1.21.42.01.21.41.41.20.8-0.91.11.31.31.11.4
Saline control response0.10.20.3-0.5-0.5-0.5-0.2-0.10.5-0.5-0.5-0.3-0.5-0.3
Bone: connectivity density0.40.61.5-0.7-0.7-0.6-1.2-1.01.1-0.9-0.6-0.5-0.6-0.3
Bone: cortical apparent density0.40.52.60.1-0.3-0.1-0.60.6-0.9-0.4-0.4-0.4-1.0-1.6
Bone: cortical area6.19.410.83.33.33.32.82.9-2.93.13.23.13.22.6
Bone: cortical porosity0.30.30.5-0.7-0.7-0.7-0.4-0.60.7-0.4-0.6-0.6-0.4-0.3
Bone: cortical porosity0.10.10.3-0.3-0.4-0.4-0.30.10.1-0.3-0.4-0.5-0.4-0.3
Bone: cortical thickness3.35.47.32.72.42.61.62.5-2.62.02.42.12.41.9
Bone: cortical thickness0.20.20.90.40.10.4-0.60.1-0.30.20.40.30.40.9
Bone: cortical tissue density0.50.73.20.0-0.4-0.3-0.70.6-0.9-0.5-0.5-0.5-1.1-1.8
Condit. Reinf. active minus inactive responses1.82.02.7-1.5-1.6-1.6-1.1-1.11.0-1.3-1.6-1.5-1.6-1.2
Condit. Reinf. active-inactive response ratio3.74.05.6-2.2-2.2-2.4-1.3-1.81.7-1.7-2.2-2.0-2.2-1.7
Condit. Reinf. active responses0.70.91.2-0.9-1.0-1.0-1.0-0.70.6-1.1-1.1-1.0-1.1-0.8
Condit. Reinf. inactive responses1.51.93.51.71.61.90.41.1-1.20.81.51.41.51.2
Incentive salience index mean0.10.20.3-0.3-0.4-0.4-0.4-0.40.2-0.4-0.6-0.4-0.6-0.2
Condit. Reinf. lever presses0.81.21.91.31.21.40.50.7-1.00.90.91.31.01.3
Condit. Reinf. active minus inactive responses0.60.81.20.81.00.91.10.9-0.50.90.91.10.80.3
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.3-0.2-0.50.20.2-0.2-0.3-0.2-0.4-0.3
Condit. Reinf. active responses0.10.10.5-0.10.30.00.7-0.00.30.40.30.40.2-0.3
Condit. Reinf. inactive responses0.10.10.3-0.3-0.0-0.20.2-0.60.5-0.10.00.00.0-0.6
Condit. Reinf. lever presses0.30.40.80.70.70.70.50.9-0.70.60.80.70.60.0
Condit. Reinf. lever reinforcers received0.20.20.60.20.50.30.80.20.10.60.60.70.40.2
Conditioned reinforcement - actives0.50.81.60.90.80.80.70.8-0.81.10.81.00.81.3
Conditioned reinforcement - inactives0.71.11.80.91.00.91.40.8-1.01.31.01.11.00.9
Conditioned locomotion1.21.62.21.41.31.40.91.1-1.21.21.21.31.21.5
Patch foraging indifference point 0 sec0.10.10.3-0.2-0.2-0.2-0.4-0.20.1-0.5-0.3-0.2-0.4-0.6
Patch foraging indifference point AUC0.60.83.4-0.9-0.7-1.0-0.1-0.30.6-0.4-0.8-0.9-0.9-1.9
Delay disc. indifference point, 0s delay0.80.95.20.90.40.8-0.40.7-0.50.60.80.80.82.3
Delay disc. indifference point, 16s delay0.20.20.4-0.4-0.5-0.5-0.5-0.30.2-0.2-0.4-0.5-0.7-0.6
Delay disc. indifference point, 2s delay0.10.21.20.1-0.20.1-0.70.10.2-0.00.10.00.21.1
Delay disc. indifference point, 24s delay0.10.10.40.40.00.2-0.20.4-0.40.40.30.20.00.6
Delay disc. indifference point, 4s delay0.20.20.6-0.3-0.4-0.3-0.8-0.30.7-0.4-0.3-0.3-0.20.4
Delay disc. indifference point, 8s delay0.81.01.60.91.00.91.21.0-0.91.31.01.00.80.8
Indifference point function ln k0.20.30.8-0.3-0.3-0.2-0.7-0.90.5-0.8-0.3-0.3-0.30.3
Indifference point function log k0.20.30.8-0.3-0.3-0.2-0.7-0.90.5-0.8-0.3-0.3-0.30.3
Patch foraging total patch changes 0 sec0.10.10.4-0.1-0.2-0.2-0.3-0.1-0.0-0.4-0.3-0.2-0.4-0.7
Patch foraging total patch changes 12 sec0.20.30.60.70.60.60.20.8-0.60.60.30.60.4-0.5
Patch foraging total patch changes 18 sec0.20.21.3-0.4-0.4-0.50.20.00.0-0.1-0.4-0.4-0.5-1.1
Patch foraging total patch changes 24 sec0.10.20.8-0.3-0.5-0.5-0.20.1-0.3-0.1-0.3-0.5-0.4-0.9
Patch foraging total patch changes 6 sec0.10.21.6-0.2-0.1-0.30.30.2-0.2-0.1-0.3-0.3-0.4-1.3
Patch foraging time to switch 0 sec1.02.05.41.61.11.50.41.5-1.41.11.31.21.42.3
Patch foraging water rate 0 sec0.30.73.00.51.10.61.70.5-0.40.90.70.70.5-0.6
Patch foraging water rate 12 sec0.20.51.7-0.7-0.6-0.80.1-0.10.1-0.7-0.8-0.9-0.8-1.3
Patch foraging water rate 18 sec0.20.21.4-0.1-0.1-0.2-0.00.3-0.4-0.5-0.3-0.6-0.4-1.2
Patch foraging water rate 24 sec0.30.41.20.40.60.31.10.9-0.80.20.10.10.0-1.0
Patch foraging water rate 6 sec0.50.81.50.91.10.91.21.0-1.20.60.60.60.6-0.5
Seeking ratio, delayed vs. immediate footshock2.32.84.2-1.8-1.6-1.7-1.3-1.71.7-1.7-1.7-1.6-1.7-2.0
Distance traveled before self-admin1.01.31.8-1.3-1.3-1.3-1.1-1.31.2-1.0-1.1-1.0-1.1-0.8
Distance traveled after self-admin0.10.21.00.1-0.20.1-1.0-0.20.2-0.3-0.1-0.1-0.10.7
Extensor digitorum longus weight1.97.512.53.22.93.02.33.4-3.52.32.52.52.41.4
Bone: elastic displacement1.31.51.91.21.31.21.21.4-0.91.31.31.31.30.4
Bone: elastic work3.74.96.52.42.42.42.12.6-2.22.02.32.12.31.1
Bone: endosteal estimation1.73.86.31.62.11.82.51.2-1.02.22.12.02.32.1
Bone: endosteal perimeter1.83.85.21.72.11.92.31.4-1.12.12.12.22.02.0
Epididymis fat weight2.06.88.12.92.72.72.42.6-2.72.92.42.82.42.1
Delta time in closed arm before/after self-admin1.11.01.4-1.0-1.1-1.0-1.1-0.91.1-1.0-0.9-1.2-0.9-0.7
Delta time in open arm before/after self-admin1.91.92.61.51.41.51.21.3-1.61.31.31.41.31.5
Diff in mean of infusions in LGA sessions1.11.32.0-1.2-1.4-1.3-1.3-1.10.9-1.0-1.1-1.3-1.1-0.6
Delay discount exponential model param0.20.20.8-0.4-0.2-0.4-0.1-0.50.3-0.6-0.5-0.4-0.3-0.9
Extinction: sum of active levers before priming1.01.12.21.00.91.01.01.0-0.91.11.00.81.01.5
Active lever presses in extinction session 60.10.10.30.2-0.20.1-0.50.1-0.2-0.2-0.0-0.0-0.00.6
Bone: final force5.79.110.83.13.23.22.92.8-2.63.03.33.03.32.8
Bone: final moment4.47.08.52.82.82.82.52.5-2.42.52.82.52.92.5
Food consumed during 24 hour testing period0.10.10.3-0.10.1-0.10.4-0.60.2-0.10.1-0.10.1-0.5
Glucose0.71.26.3-0.10.6-0.02.5-0.40.31.21.10.61.11.4
Heart weight1.72.74.11.51.71.51.91.4-1.21.51.71.71.72.0
Delay discount hyperbolic model param0.20.21.0-0.4-0.2-0.3-0.0-0.40.2-0.5-0.4-0.4-0.3-1.0
Intermittent access intake day 1-15 change2.65.46.2-2.5-2.5-2.5-2.3-2.12.3-2.1-2.3-2.1-2.3-2.3
Intermittent access intake escalation1.73.54.1-2.0-2.0-2.0-1.9-1.71.9-1.7-1.9-1.7-1.9-1.9
Intermittent access intake escalation 22.93.34.5-1.9-1.8-1.9-1.7-1.71.8-1.7-1.8-1.6-1.8-2.1
Intermitt. access day 1 inactive lever presses0.20.71.1-0.8-0.8-0.7-0.9-0.90.8-1.1-0.8-0.7-0.8-0.9
Intermitt. access day 15 inactive lever presses0.40.91.5-1.2-1.0-1.2-0.2-0.80.9-0.6-0.9-1.1-0.9-1.1
Intermitt. access escalation Index0.71.01.2-1.1-1.0-1.1-0.9-0.91.0-0.8-1.0-0.8-1.0-1.1
Intermittent access day 1 total infusions0.91.43.11.21.01.11.00.9-1.11.41.11.21.11.8
Intermittent access day 15 total infusions0.00.00.2-0.1-0.1-0.20.2-0.10.00.5-0.00.2-0.00.2
Intermittent access terminal intake (last 3 days)0.10.10.2-0.4-0.3-0.50.2-0.30.30.3-0.30.0-0.3-0.2
Intermittent access total infusions0.20.20.70.40.40.30.70.3-0.40.80.40.60.40.5
Intermittent access day 1 locomotion0.81.01.60.90.90.91.00.8-0.91.20.91.00.91.3
Intermittent access day 15 total locomotion0.20.41.40.60.50.60.40.4-0.60.80.60.70.61.2
Intermittent access total locomotion0.00.00.20.00.0-0.00.3-0.0-0.10.40.10.30.10.4
Intermittent access standard deviation0.30.71.1-1.0-0.9-1.1-0.5-0.70.8-0.5-0.8-0.9-0.8-0.9
Left kidney weight3.918.024.34.84.44.63.64.9-4.93.74.23.74.13.3
Right kidney weight3.013.518.64.13.73.93.04.3-4.33.33.73.13.63.1
Cocaine induced anxiety0.70.91.7-1.0-1.0-1.0-0.7-0.80.8-1.1-0.8-1.3-0.8-1.1
Post-drug Anxiety0.30.30.9-0.5-0.7-0.5-0.8-0.30.4-0.7-0.4-0.9-0.4-0.1
Baseline Anxiety2.02.45.11.61.31.60.81.5-1.41.71.41.51.42.3
Tail length0.93.65.71.92.11.92.41.9-1.72.01.91.61.91.5
Length with tail4.218.422.44.44.74.44.74.1-3.94.44.44.24.23.7
Length without tail3.912.614.83.73.83.73.63.3-3.23.53.63.83.43.4
Times rat made contact with spout1.11.22.5-1.3-1.0-1.3-0.1-1.61.2-0.8-0.9-1.1-0.9-1.2
Lifetime Intake0.20.30.80.40.40.30.80.3-0.40.90.40.70.40.5
Liver weight, left0.61.01.31.01.01.01.11.1-0.91.01.00.91.01.0
Liver weight, right2.13.66.62.32.12.11.72.3-2.61.91.41.81.50.7
Locomotor activity0.40.63.70.10.70.21.9-0.10.11.10.70.60.6-0.0
Locomotor testing distance0.61.12.20.91.10.91.50.9-0.91.21.10.91.10.7
Locomotor testing rearing1.12.34.81.41.61.42.21.3-1.41.71.61.41.50.9
Locomotion in novel chamber0.50.61.0-0.9-1.0-1.0-0.8-0.70.7-0.9-0.7-0.5-0.7-0.8
Locomotion in novel chamber post-restriction0.00.10.3-0.3-0.3-0.40.3-0.1-0.00.20.10.20.10.5
Fecal boli incidents, locomotor time 10.40.61.3-0.7-0.7-0.7-0.6-0.80.6-0.8-0.7-0.4-0.9-1.2
Change in fecal boli incidents, locomotor task0.50.50.8-0.9-0.7-0.9-0.1-0.50.8-0.5-0.5-0.8-0.6-0.9
Time >=10cm from walls, locomotor time 11.61.72.31.51.21.40.91.3-1.41.41.31.21.21.5
Bouts of movement, locomotor time 10.10.10.60.50.20.4-0.30.3-0.80.20.20.10.1-0.0
Total resting periods, locomotor time 10.10.10.50.40.20.3-0.10.3-0.70.30.30.20.20.0
Rest time, locomotor task time 11.92.33.51.61.81.61.91.3-1.71.71.51.61.30.5
Distance moved, locomotor task time 10.30.40.9-0.4-0.6-0.4-1.0-0.10.4-1.0-0.6-0.8-0.5-0.3
Vertical activity count, locomotor time 10.71.62.1-1.3-1.4-1.3-1.3-1.11.4-1.4-1.2-1.4-1.3-0.8
Time >=10cm from walls, locomotor time 20.71.02.11.01.00.91.30.9-0.81.40.91.30.70.6
Bouts of movement, locomotor time 20.10.10.3-0.1-0.3-0.2-0.5-0.2-0.1-0.1-0.3-0.1-0.4-0.5
Total resting periods, locomotor time 20.00.00.10.20.00.1-0.10.2-0.40.30.00.2-0.1-0.2
Rest time, locomotor task time 21.31.63.01.21.41.21.71.2-1.21.51.21.11.10.8
Distance moved, locomotor task time 20.70.82.0-0.7-0.9-0.7-1.4-0.60.8-1.2-0.9-0.8-0.6-0.6
Vertical activity count, locomotor time 21.41.93.5-1.3-1.5-1.2-1.9-1.41.7-1.6-1.4-1.0-1.1-0.7
Light reinforcement 11.53.75.82.22.02.11.72.4-2.41.81.81.81.80.9
Light reinforcement 22.43.65.82.42.22.41.12.0-2.31.21.81.91.81.4
Bone: marrow area1.63.55.81.52.01.72.41.1-0.92.12.01.92.22.1
Bone: maximum diameter3.36.17.72.72.72.62.52.6-2.82.32.42.32.41.5
Bone: maximum force4.07.08.32.82.92.82.62.5-2.32.72.92.62.82.2
Bone: maximum moment2.95.16.22.42.52.42.32.2-2.12.22.42.12.41.9
Mean time between licks in bursts0.61.63.1-1.4-1.1-1.3-0.5-1.81.4-1.3-1.2-1.2-1.2-1.0
Mean num. licks in bursts3.35.28.4-2.7-2.6-2.9-1.0-2.02.0-1.6-2.4-2.3-2.4-2.4
Cd content in liver0.10.10.5-0.20.1-0.20.70.10.40.40.10.20.10.6
Co content in liver1.11.33.60.70.90.81.20.5-0.21.11.51.01.51.9
Cu content in liver0.80.92.0-1.2-1.1-1.2-0.6-1.41.2-0.8-0.6-0.9-0.6-0.7
Fe content in liver3.64.36.4-2.4-2.5-2.4-1.8-2.52.2-1.9-1.6-2.2-1.6-1.2
K content in liver0.10.10.20.20.10.3-0.40.30.10.30.40.40.40.2
Mg content in liver1.21.21.91.31.21.30.41.4-1.11.11.11.21.10.6
Mn content in liver0.10.20.6-0.5-0.2-0.3-0.4-0.30.8-0.3-0.4-0.2-0.4-0.3
Na content in liver0.20.20.7-0.4-0.4-0.4-0.1-0.70.70.10.3-0.00.30.8
Rb content in liver0.50.61.30.40.50.51.0-0.0-0.20.81.10.71.11.2
Se content in liver1.01.14.0-0.5-0.8-0.6-1.50.40.0-1.2-1.0-1.1-1.0-2.0
Sr content in liver1.51.32.81.41.31.40.81.7-1.40.80.91.10.90.2
Zn content in liver0.40.41.9-0.1-0.3-0.2-0.70.5-0.5-0.8-0.7-0.7-0.6-1.4
Bone: minimum diameter2.03.65.21.72.11.92.31.2-1.12.12.12.02.12.1
Time in familiar zone, hab. session 11.11.01.6-1.1-1.2-1.2-0.9-0.90.8-1.2-0.9-1.2-0.9-0.5
Time in novel zone, hab. session 10.40.41.10.70.80.70.31.0-0.70.50.20.60.3-0.8
Total zone transitions, hab. session 10.10.20.9-0.4-0.3-0.3-0.0-0.90.5-0.2-0.3-0.2-0.20.5
Total locomotion distance, hab. session 10.40.62.0-0.9-0.6-0.8-0.2-1.41.1-0.5-0.6-0.5-0.60.5
Locomotion velocity, hab. session 10.30.42.2-0.4-0.1-0.20.4-1.10.80.20.10.20.11.5
Time in familiar zone, hab. session 24.34.55.8-2.2-2.4-2.2-2.3-1.91.9-2.3-2.1-2.3-2.1-1.5
Time in novel zone, hab. session 25.85.87.52.62.72.52.72.7-2.62.52.12.42.21.1
Total zone transitions, hab. session 20.00.10.3-0.1-0.1-0.20.10.0-0.2-0.2-0.2-0.3-0.1-0.5
Total locomotion distance, hab. session 20.10.10.3-0.3-0.3-0.40.2-0.1-0.1-0.3-0.3-0.5-0.3-0.5
Locomotion velocity, hab. session 20.00.10.2-0.3-0.2-0.30.2-0.2-0.0-0.3-0.2-0.4-0.2-0.3
Novel to familiar place preference ratio0.00.10.2-0.2-0.2-0.20.1-0.50.40.2-0.10.1-0.10.2
Novelty place preference0.00.00.1-0.1-0.0-0.10.3-0.30.20.30.00.10.00.1
Time in novel zone, NPP test0.00.00.10.00.10.00.3-0.20.10.30.00.20.00.1
Total zone transitions, NPP test0.10.10.5-0.1-0.2-0.0-0.6-0.50.2-0.4-0.3-0.1-0.20.7
Total locomotion distance, NPP test0.40.61.0-0.7-0.8-0.7-0.9-1.00.7-0.8-0.8-0.7-0.80.2
Locomotion velocity, NPP test0.60.91.5-1.0-1.1-1.0-1.0-1.20.9-0.8-0.9-0.9-0.90.1
Intraocular pressure0.10.20.70.60.40.50.10.8-0.80.20.10.00.2-0.5
Delta distance traveled before/after self-admin0.70.81.71.10.81.1-0.10.9-0.80.60.80.70.81.3
Delta ambulatory time before/after self-admin0.10.21.20.1-0.20.2-1.1-0.10.2-0.6-0.2-0.2-0.20.4
Parametrial fat weight0.30.71.8-1.1-1.1-1.3-0.0-0.50.6-0.3-0.6-1.0-0.7-0.8
Pavlov. Cond. lever latency1.31.73.3-1.5-1.4-1.7-0.4-0.91.0-0.9-1.3-1.4-1.4-1.8
Pavlov. Cond. magazine entry latency0.91.22.1-0.9-1.0-0.9-1.4-0.90.8-1.5-1.3-1.0-1.3-0.8
Pavlov. Cond. change in total contacts0.10.10.40.20.20.3-0.3-0.30.10.0-0.20.3-0.10.7
Pavlov. Cond. index score0.10.10.70.10.00.3-0.8-0.30.2-0.4-0.20.1-0.00.6
Pavlov. Cond. latency score0.10.20.80.40.30.5-0.5-0.10.0-0.20.10.30.20.9
Pavlov. Cond. lever contacts1.01.22.81.21.21.40.20.6-0.70.71.11.21.11.7
Pavlov. Cond. magazine entry number1.21.52.21.21.21.11.51.2-1.21.51.41.11.30.6
Pavlov. Cond. intertrial magazine entries0.10.20.70.50.20.3-0.30.7-0.8-0.00.2-0.10.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.20.10.4-0.7-0.20.2-0.3-0.10.20.10.7
Pavlov. Cond. response bias0.20.31.2-0.2-0.3-0.0-1.1-0.50.4-0.8-0.5-0.2-0.40.3
Pavlov. Cond. lever latency0.40.61.50.90.60.90.11.0-0.90.40.50.50.81.2
Pavlov. Cond. magazine entry latency1.31.62.21.31.31.21.31.0-1.31.31.51.21.41.0
Pavlov. Cond. change in total contacts0.00.00.10.00.10.00.10.0-0.10.1-0.00.2-0.1-0.4
Pavlov. Cond. index score0.00.00.20.00.10.00.3-0.1-0.10.20.10.2-0.0-0.5
Pavlov. Cond. latency score0.00.00.20.00.10.00.2-0.1-0.10.20.10.1-0.0-0.5
Pavlov. Cond. lever contacts0.71.01.6-1.2-1.0-1.1-0.5-1.31.2-0.6-0.8-0.7-1.0-1.2
Pavlov. Cond. magazine entry number1.72.12.7-1.5-1.6-1.5-1.7-1.21.6-1.5-1.5-1.5-1.4-0.8
Pavlov. Cond. intertrial magazine entries0.50.81.7-0.8-0.7-0.6-1.3-1.01.2-1.1-0.6-0.7-0.7-0.6
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.10.20.10.3-0.0-0.20.20.20.20.0-0.4
Pavlov. Cond. response bias0.00.10.2-0.2-0.1-0.20.2-0.40.20.10.10.1-0.2-0.4
Time in closed arm before self-admin0.10.10.30.40.40.50.40.3-0.60.20.30.30.30.2
Time in closed arm after self-admin0.50.60.9-0.6-0.7-0.6-0.9-0.70.7-0.8-0.7-0.9-0.7-0.7
Time in open arm before self-admin0.20.20.40.40.50.40.70.4-0.00.50.50.50.50.2
Time in open arm after self-admin2.02.22.61.61.61.61.41.4-1.41.41.41.61.41.4
Bone: periosteal estimation4.69.711.93.03.33.13.42.5-2.43.33.33.23.43.1
Bone: periosteal perimeter5.29.010.72.93.13.03.12.6-2.33.23.33.23.12.9
Bone: post-yield work0.71.01.6-0.9-1.0-1.0-1.0-0.90.7-1.2-1.1-1.2-0.9-0.9
Progressive ratio test 1 active lever presses1.11.42.71.11.11.01.30.9-1.11.61.11.41.11.3
Progressive ratio test 1 breakpoint1.11.42.61.11.01.01.20.9-1.01.61.01.41.01.4
Progressive ratio test 1 inactive lever presses0.20.30.80.40.50.40.90.3-0.50.70.50.70.50.6
Progressive ratio test 2 active lever presses0.10.10.30.20.10.20.10.0-0.20.40.20.20.20.5
Progressive ratio test 2 breakpoint0.10.10.40.20.10.20.10.1-0.20.40.20.30.20.6
Progressive ratio test 2 inactive lever presses0.40.71.40.70.70.61.20.6-0.81.10.80.80.81.0
Incentive Sensitization - Responses0.10.10.3-0.3-0.4-0.2-0.5-0.40.2-0.5-0.2-0.4-0.20.1
Incentive Sensitization - Breakpoint0.10.10.2-0.2-0.3-0.2-0.5-0.30.2-0.4-0.2-0.4-0.20.1
Sum of active levers in priming session hrs 5-60.10.10.60.1-0.30.1-0.8-0.10.1-0.6-0.2-0.0-0.20.6
Progressive ratio0.30.50.90.50.60.41.00.6-0.60.80.70.70.70.7
Food seeking constrained by brief footshock2.43.03.91.81.91.91.31.4-1.41.71.72.01.71.9
Seeking ratio, punishment vs. effort0.00.10.20.30.30.4-0.3-0.10.1-0.10.10.20.10.2
Retroperitoneal fat weight0.51.93.81.21.21.01.71.5-1.42.01.31.51.21.1
Reaction time number correct0.40.72.80.71.00.61.70.9-1.00.50.50.50.6-0.6
Reaction time mean minus median0.61.62.4-1.5-1.4-1.6-0.7-1.41.4-1.0-1.1-1.1-1.2-0.9
Reaction time mean minus median AUC0.00.10.3-0.0-0.0-0.10.60.1-0.20.40.20.20.20.3
Reaction time num false alarms0.91.32.71.40.91.4-0.21.4-1.20.81.10.91.01.7
Reaction time num false alarms AUC1.21.93.31.71.21.7-0.11.8-1.60.91.21.11.21.6
Reaction time trials correct on left0.40.72.80.71.00.61.70.9-1.00.50.50.50.6-0.6
Reaction time trials on left0.30.62.50.50.90.51.60.8-1.00.40.40.40.5-0.7
Reaction time mean0.91.52.1-1.3-1.4-1.3-1.4-1.31.4-1.2-1.0-1.1-1.0-0.4
Reaction time mean AUC0.81.41.9-1.3-1.4-1.3-1.3-1.31.3-1.1-1.0-1.1-1.0-0.5
Median of all reaction times0.71.12.2-1.0-1.2-1.0-1.5-1.11.3-1.0-0.8-0.9-0.8-0.1
Reaction time omissions0.91.42.3-1.3-1.4-1.5-0.5-0.80.6-0.9-1.3-1.4-1.2-1.2
Reaction time false alarm rate0.81.12.61.30.61.3-1.01.3-1.00.50.80.70.71.6
Reaction time premature initiation rate0.00.10.30.0-0.2-0.1-0.50.1-0.3-0.3-0.2-0.2-0.2-0.3
Reaction time premature initiations0.10.20.60.20.20.10.50.5-0.80.00.0-0.10.1-0.7
Std. dev. reaction times0.61.22.0-1.3-1.4-1.4-0.8-1.11.0-0.9-1.0-1.1-1.1-0.8
Reaction time trials completed0.30.62.50.50.90.51.60.8-1.00.40.40.40.5-0.7
Reaction time trials AUC0.30.62.40.50.80.51.50.8-0.90.40.30.40.4-0.7
Run reversals in cocaine runway, females1.11.13.4-0.9-1.3-0.9-1.9-1.01.0-1.2-0.7-1.1-0.90.2
Run reversals in cocaine runway, males0.20.20.60.40.50.40.60.6-0.60.80.20.40.30.2
Latency to leave start box in cocaine runway1.41.62.91.21.01.11.21.2-1.21.11.41.21.31.7
Latency to leave start box in cocaine runway, F2.83.24.21.91.81.91.61.7-1.71.81.81.71.72.0
Latency to leave start box in cocaine runway, M0.10.10.1-0.2-0.3-0.30.3-0.0-0.0-0.30.2-0.00.20.4
Std. dev. time between licks in bursts0.10.20.8-0.40.0-0.20.6-0.90.70.30.10.20.10.3
Total sessions with >9 infusions0.20.20.70.20.30.10.80.3-0.40.90.40.50.40.6
Short access day 1 total inactive lever presses0.10.10.40.10.20.10.60.2-0.20.40.20.30.20.0
Short access day 10 total inactive lever presses0.61.43.8-1.2-0.9-1.2-0.6-1.11.1-1.3-1.1-0.9-1.1-1.9
Short access day 1 total infusions0.10.10.50.10.10.00.50.2-0.20.70.20.70.20.5
Short access day 10 total infusions0.00.10.3-0.00.1-0.10.6-0.0-0.10.40.10.20.10.0
Short access total infusions0.00.10.2-0.10.0-0.10.5-0.1-0.00.40.00.40.00.0
Short access day 1 locomotion0.40.50.80.80.80.80.60.7-0.70.70.70.60.70.9
Short access day 10 total locomotion1.42.73.7-1.8-1.7-1.9-1.2-1.61.6-1.4-1.6-1.5-1.6-1.9
Short access total locomotion0.60.71.1-1.0-0.9-1.1-0.3-0.90.8-0.5-0.8-0.7-0.8-0.9
One hour access (0.3 mA shock)0.10.10.40.10.20.10.60.0-0.20.60.20.40.2-0.1
Compulsive drug intake0.20.31.3-0.2-0.3-0.1-1.1-0.10.4-0.8-0.4-0.4-0.4-0.3
One hour access (shock baseline)0.10.10.70.00.1-0.10.8-0.1-0.20.70.20.40.20.1
Social response proportion1.71.92.9-1.3-1.2-1.2-1.3-1.11.2-1.7-1.4-1.4-1.5-1.7
Social responses0.10.21.4-0.2-0.0-0.20.30.1-0.1-0.4-0.2-0.4-0.3-1.2
Social time0.91.21.6-1.3-1.2-1.2-0.9-1.31.3-1.1-1.1-0.9-1.1-0.9
Soleus weight1.75.09.22.72.52.61.93.0-3.01.52.01.81.90.8
Bone: stiffness1.93.16.21.51.71.61.80.8-0.92.12.01.81.92.5
Tibialis anterior weight1.13.86.02.12.02.02.02.3-2.51.91.71.81.61.0
Time to tail flick, vehicle, before self-admin0.70.71.6-0.8-1.0-0.8-1.3-0.70.8-0.9-0.9-0.5-0.9-0.3
Time to tail flick, vehicle, after self-admin0.50.71.4-1.0-1.0-1.2-0.4-0.60.5-0.6-0.9-0.8-0.9-1.0
Time to tail flick, test, before self-admin0.20.21.10.00.2-0.11.00.3-0.40.70.30.20.3-0.2
Time to tail flick, test, after self-admin0.50.51.60.60.90.71.30.6-0.50.80.70.70.70.0
Delta time to tail flick, vehicle, before/after SA0.20.21.00.10.20.01.00.4-0.40.50.30.10.3-0.1
Delta time to tail flick, test, before/after SA0.00.00.20.10.20.2-0.00.10.1-0.30.00.20.0-0.4
Tibia length1.64.35.82.32.22.41.51.6-1.42.12.42.32.22.1
Ambulatory time before self-admin0.60.91.3-1.1-1.1-1.1-1.0-1.10.9-0.8-0.9-0.8-0.9-0.3
Ambulatory time after self-admin1.01.24.1-0.8-1.2-0.7-2.0-1.11.0-1.3-0.9-1.0-0.90.1
Bone: tissue strength1.41.43.01.11.41.21.71.4-1.21.01.10.91.00.2
Total heroin consumption0.40.51.00.70.80.71.00.6-0.90.50.60.60.60.7
Bone: trabecular number0.71.23.0-0.7-0.9-0.7-1.7-0.90.7-1.4-1.0-1.0-1.2-1.2
Bone: trabecular spacing2.02.64.01.51.81.52.01.4-1.21.81.61.71.61.5
Bone: trabecular thickness1.31.64.7-0.9-1.0-0.7-2.2-1.61.1-1.7-1.1-1.0-1.1-0.6
Bone: trabecular tissue density0.10.21.0-0.4-0.3-0.3-0.4-1.00.7-0.2-0.2-0.1-0.20.4
Water consumed over 24 hours0.81.12.2-1.3-0.9-1.2-0.0-1.51.3-0.9-0.9-1.0-0.9-1.1
Number of responses in last shaping day0.10.11.1-0.0-0.3-0.1-0.4-0.10.00.1-0.0-0.0-0.01.0