Hub : Genes

LOC134481231

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression LOC134481231 0.32 0.04 0.0e+00 0.37 0.4 0.39 0.4 2.3e-16 7.0e-18 2.6e-17 7.2e-18
2 PL gene expression LOC134481231 0.18 0.01 0.0e+00 0.4 0.46 0.47 0.46 4.2e-47 2.4e-55 5.1e-57 5.0e-56
3 BLA gene expression LOC134481231 0.28 0.04 0.0e+00 0.33 0.45 0.45 0.45 4.2e-18 3.0e-26 3.2e-26 2.0e-26
4 NAcc gene expression LOC134481231 0.13 0 0.0e+00 0.43 0.48 0.49 0.48 6.8e-71 5.4e-83 1.8e-85 1.6e-83
5 pVTA intron excision ratio chr12_1889703_1892293 0.04 0.04 1.1e-03 0.04 0.04 0.04 0.04 5.6e-04 3.9e-04 2.1e-04 2.9e-04
6 PL intron excision ratio chr12_1872855_1875021 0.03 0.02 5.6e-04 0.03 0.03 0.03 0.02 7.2e-04 7.6e-04 5.3e-04 1.3e-03
7 OFC gene expression LOC134481231 0.42 0.16 2.0e-06 0.17 0.18 0.17 0.17 7.7e-05 5.6e-05 8.2e-05 8.2e-05
8 IL gene expression LOC134481231 0.3 0.2 5.6e-04 0.08 0.13 0.13 0.12 5.8e-03 5.0e-04 6.3e-04 7.1e-04
9 pVTA intron excision ratio chr12_1875862_1880232 0.03 0.02 3.1e-03 0.05 0.04 0.03 0.04 8.4e-05 4.7e-04 3.5e-03 2.4e-04
10 Brain gene expression LOC134481231 0.08 0.01 0.0e+00 0.4 0.42 0.44 0.44 3.5e-40 1.0e-42 6.1e-45 2.8e-44
11 Brain intron excision ratio chr12_1875157_1875760 0.05 0.03 1.8e-05 0.04 0.05 0.06 0.06 8.5e-05 1.1e-05 2.8e-06 7.0e-06
12 RMTg intron excision ratio chr12_1892430_1924047 0.34 0.29 3.7e-04 0.12 0.11 0.11 0.12 5.7e-04 6.3e-04 7.7e-04 3.6e-04
13 NAcc intron excision ratio chr12_1871015_1872672 0.1 0.02 0.0e+00 0.13 0.14 0.14 0.13 4.7e-19 9.0e-21 7.3e-20 1.3e-19
14 pVTA intron excision ratio chr12_1871015_1872672 0.19 0.02 1.1e-04 0.03 0.07 0.08 0.04 1.6e-03 4.8e-06 5.8e-07 4.4e-04
15 NAcc intron excision ratio chr12_1872855_1875021 0.04 0.03 4.9e-07 0.04 0.04 0.04 0.04 4.1e-07 2.4e-07 2.3e-07 7.2e-07
16 PL intron excision ratio chr12_1880436_1889560 0.3 0 3.0e-05 0.02 0.05 0.04 0.04 6.9e-03 3.7e-06 5.2e-05 4.4e-05
17 Brain intron excision ratio chr12_1872855_1875021 0.05 0.05 5.6e-03 0.02 0.02 0.03 0.03 3.8e-03 2.2e-03 1.1e-03 2.0e-03
18 RMTg gene expression LOC134481231 0.55 0.04 7.7e-09 0.36 0.32 0.37 0.37 1.4e-10 3.7e-09 1.2e-10 8.7e-11
19 NAcc intron excision ratio chr12_1880436_1889560 0.12 0.01 2.9e-07 0.01 0.06 0.06 0.04 6.6e-03 9.1e-09 5.9e-10 3.5e-07
20 PL intron excision ratio chr12_1871015_1872672 0.18 0 2.0e-06 -0 0.07 0.08 0.06 4.4e-01 5.0e-08 8.8e-09 1.4e-07
21 pVTA gene expression LOC134481231 0.19 0.01 0.0e+00 0.42 0.44 0.4 0.46 1.3e-36 4.2e-39 1.3e-34 1.5e-40
22 LHb gene expression LOC134481231 0.66 0 6.1e-07 0.23 0.2 0.18 0.22 4.3e-06 1.3e-05 4.1e-05 7.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density3.15.810.9-3.23.3-2.83.3-2.72.9-3.1-3.1-2.82.92.92.8-2.72.11.41.51.41.2-0.50.00.00.0
Area under the delay curve1.32.07.11.00.21.4-0.01.5-1.30.90.71.4-1.3-1.4-1.21.4-2.1-1.0-2.60.30.22.7-2.50.20.9
BMI with tail1.34.59.2-2.62.7-2.03.0-1.92.6-2.9-3.0-2.42.12.12.6-2.91.2-0.00.72.62.2-0.40.00.00.0
BMI without tail1.68.515.9-3.73.7-3.24.0-3.13.7-3.9-3.9-3.63.23.23.5-3.62.30.71.62.72.4-0.60.10.00.0
Body weight10.144.477.2-8.58.5-7.98.8-7.98.4-8.7-8.7-8.57.87.58.0-7.65.73.34.24.53.7-1.20.40.00.0
Weight adjusted by age0.30.82.2-0.90.4-1.10.5-1.31.0-0.8-0.9-1.11.11.11.0-0.81.20.61.50.20.2-0.80.9-0.60.1
Bone surface3.67.113.1-3.53.4-3.03.6-3.13.3-3.5-3.5-3.23.13.23.2-3.12.21.21.71.91.6-0.40.00.00.0
Bone volume1.63.16.2-2.22.2-1.82.5-1.82.1-2.4-2.4-2.11.92.02.1-2.21.20.20.91.91.7-0.3-0.00.00.0
Breakpoint value in progressive ratio session0.20.31.9-0.20.5-0.20.5-0.2-0.1-0.1-0.2-0.10.10.1-0.00.4-0.50.2-0.7-0.2-0.31.2-1.4-0.60.9
Number of licking bursts0.00.00.1-0.0-0.1-0.2-0.1-0.2-0.00.00.0-0.10.10.2-0.00.10.10.30.3-0.3-0.4-0.20.20.00.0
Context. condit. distance diff. score2.42.95.0-2.22.2-2.12.2-2.12.1-2.1-2.1-2.02.12.22.0-1.71.71.31.30.50.4-0.30.00.00.0
Locomotion velocity, session 10.30.40.70.7-0.50.7-0.70.7-0.70.80.80.8-0.5-0.8-0.80.7-0.40.1-0.5-0.6-0.60.2-0.10.00.0
Locomotion distance, session 11.62.13.71.8-1.71.8-1.81.8-1.81.91.91.7-1.6-1.6-1.81.6-1.2-0.4-1.0-1.2-1.00.2-0.10.00.0
Locomotion velocity, session 20.40.40.90.8-0.70.8-0.80.8-0.80.90.90.9-0.7-0.9-0.90.7-0.5-0.2-0.5-0.5-0.40.3-0.10.00.0
Locomotion distance, session 22.53.56.72.3-2.32.0-2.61.9-2.32.62.62.3-1.9-1.9-2.32.4-1.20.0-0.9-2.2-2.00.3-0.10.00.0
Locomotion velocity, session 30.10.20.6-0.50.7-0.50.5-0.40.4-0.3-0.3-0.30.60.30.3-0.30.50.80.2-0.3-0.4-0.20.10.00.0
Locomotion distance, session 30.10.10.4-0.10.3-0.30.1-0.0-0.10.10.10.10.20.1-0.10.00.10.60.0-0.5-0.5-0.3-0.00.00.0
Stereotopy head waving bouts, day 31.92.23.7-1.91.9-1.91.8-1.91.9-1.8-1.8-1.91.91.81.9-1.51.51.21.10.40.2-0.20.20.00.0
Stereotopy head waving duration, day 30.00.00.10.2-0.30.1-0.30.0-0.10.20.1-0.0-0.2-0.2-0.00.2-0.2-0.2-0.00.10.10.10.10.00.0
Locomotion velocity, session 70.60.71.90.9-0.91.2-0.71.2-0.90.70.70.8-1.1-1.0-0.80.4-1.0-1.4-0.80.70.80.1-0.00.00.0
Locomotion distance, session 70.30.40.70.8-0.80.8-0.70.8-0.80.70.70.8-0.8-0.7-0.80.5-0.7-0.7-0.50.00.10.0-0.10.00.0
Stereotopy head waving bouts, day 70.60.72.60.8-0.60.5-1.00.8-0.81.11.10.9-0.6-0.7-0.91.0-0.20.8-0.3-1.6-1.6-0.00.00.00.0
Stereotopy head waving duration, day 70.50.61.30.9-0.70.7-1.00.8-0.81.01.10.9-0.7-0.8-0.90.9-0.30.3-0.4-1.2-1.10.00.00.00.0
Locomotion velocity, session 80.10.10.3-0.40.5-0.30.4-0.20.3-0.3-0.3-0.10.30.20.2-0.40.20.20.00.20.2-0.1-0.00.00.0
Locomotion distance, session 80.40.51.0-0.90.9-0.80.9-0.90.9-0.9-0.9-0.90.91.00.9-0.70.70.50.60.20.2-0.1-0.10.00.0
Degree of sensitization distance0.60.72.01.0-1.21.2-0.91.0-0.90.80.70.8-1.1-0.9-0.80.6-0.9-1.4-0.60.60.70.3-0.20.00.0
Degree of sensitization stereotypy0.60.61.20.9-0.80.8-1.00.9-0.91.11.11.0-0.8-0.9-1.00.9-0.40.2-0.5-1.0-0.90.1-0.00.00.0
Conditioned locomotion0.00.00.10.2-0.20.1-0.20.0-0.00.20.10.0-0.1-0.3-0.00.1-0.0-0.1-0.0-0.1-0.10.10.10.00.0
Cocaine response after cond. corrected0.71.04.9-0.90.9-0.41.3-0.50.9-1.3-1.3-0.90.50.51.1-1.3-0.0-1.0-0.02.21.90.1-0.00.00.0
Cocaine response after cond. not corrected0.50.73.9-0.70.8-0.21.1-0.40.7-1.0-1.1-0.70.30.40.9-1.1-0.1-1.0-0.02.01.80.2-0.10.00.0
Cocaine response before conditioning0.20.21.20.3-0.30.2-0.50.2-0.40.60.60.4-0.2-0.1-0.50.70.00.60.1-1.1-0.90.1-0.00.00.0
Saline control response2.33.19.0-2.02.1-2.31.6-2.31.9-1.5-1.5-1.72.32.31.7-0.92.23.01.8-1.5-1.6-0.40.10.00.0
Bone: connectivity density5.99.416.0-4.04.0-3.74.0-3.73.7-3.9-3.9-3.73.73.93.7-3.32.82.02.21.41.1-0.50.10.00.0
Bone: cortical apparent density0.30.41.70.7-0.81.0-0.50.8-0.60.40.40.4-0.9-0.7-0.50.3-0.7-1.3-0.50.80.90.3-0.10.00.0
Bone: cortical area0.20.40.9-0.70.6-0.70.6-0.70.8-0.7-0.7-0.90.60.80.8-0.50.70.50.50.10.0-0.10.20.00.0
Bone: cortical porosity0.00.00.3-0.10.2-0.00.10.00.0-0.00.0-0.00.20.20.1-0.00.10.50.0-0.4-0.5-0.1-0.00.00.0
Bone: cortical porosity0.20.20.80.5-0.50.5-0.60.5-0.50.60.60.5-0.4-0.3-0.50.6-0.20.4-0.2-0.8-0.90.0-0.10.00.0
Bone: cortical thickness0.50.91.9-1.21.0-1.01.1-1.11.3-1.2-1.2-1.41.01.21.3-0.90.90.60.70.30.2-0.10.20.00.0
Bone: cortical thickness1.01.22.2-1.31.2-1.31.2-1.51.4-1.2-1.3-1.41.41.51.4-0.91.31.21.1-0.1-0.30.10.00.00.0
Bone: cortical tissue density0.30.41.70.7-0.71.0-0.50.8-0.60.40.40.5-0.9-0.7-0.50.3-0.8-1.3-0.50.80.90.3-0.10.00.0
Condit. Reinf. active minus inactive responses0.40.50.90.8-0.80.9-0.70.9-0.90.70.70.9-0.9-0.9-0.90.5-0.8-0.9-0.70.20.30.1-0.20.00.0
Condit. Reinf. active-inactive response ratio0.10.10.20.1-0.10.30.00.3-0.20.10.10.2-0.2-0.2-0.3-0.1-0.3-0.5-0.30.50.50.1-0.20.00.0
Condit. Reinf. active responses0.70.91.71.1-1.01.0-1.21.0-1.21.21.31.3-1.0-1.1-1.31.1-0.7-0.2-0.6-0.8-0.70.1-0.20.00.0
Condit. Reinf. inactive responses1.51.93.71.7-1.61.3-1.91.3-1.81.91.91.8-1.3-1.4-1.81.8-0.90.1-0.6-1.7-1.60.1-0.10.00.0
Incentive salience index mean1.01.22.21.4-1.31.3-1.51.3-1.41.51.51.4-1.3-1.3-1.41.2-0.9-0.4-0.7-0.8-0.70.2-0.10.00.0
Condit. Reinf. lever presses1.72.64.92.0-1.91.8-2.21.8-1.92.22.21.9-1.7-1.8-1.91.9-1.2-0.2-0.9-1.6-1.40.30.00.00.0
Condit. Reinf. active minus inactive responses1.01.62.9-1.61.5-1.61.5-1.71.5-1.5-1.5-1.51.61.71.4-1.21.31.01.20.20.2-0.2-0.00.00.0
Condit. Reinf. active-inactive response ratio0.30.50.9-0.90.9-0.90.9-0.90.8-0.9-0.9-0.80.90.90.7-0.80.60.40.60.40.4-0.2-0.10.00.0
Condit. Reinf. active responses0.81.22.0-1.31.3-1.41.2-1.41.3-1.2-1.2-1.21.41.41.3-0.91.21.21.0-0.2-0.2-0.20.10.00.0
Condit. Reinf. inactive responses0.20.30.9-0.50.5-0.60.3-0.60.5-0.3-0.3-0.50.60.60.6-0.10.71.00.4-0.7-0.60.00.20.00.0
Condit. Reinf. lever presses0.00.00.1-0.20.3-0.10.3-0.10.2-0.2-0.2-0.10.10.10.2-0.20.0-0.1-0.00.30.30.10.00.00.0
Condit. Reinf. lever reinforcers received0.30.40.8-0.70.7-0.80.6-0.90.7-0.6-0.6-0.70.80.80.7-0.30.80.90.7-0.4-0.3-0.10.10.00.0
Conditioned reinforcement - actives0.93.46.9-2.22.4-2.32.1-2.02.0-1.9-1.8-1.92.41.81.8-1.51.82.21.0-0.4-0.6-0.4-0.1-2.62.0
Conditioned reinforcement - inactives0.10.30.8-0.40.2-0.60.1-0.50.5-0.2-0.1-0.70.70.40.1-0.30.90.90.7-0.7-0.6-0.80.6-0.4-0.2
Conditioned locomotion1.92.95.1-1.92.0-2.11.7-2.11.9-1.7-1.7-1.92.11.81.7-1.01.62.21.0-0.7-1.00.2-0.4-2.21.9
Patch foraging indifference point 0 sec0.00.10.30.1-0.0-0.2-0.2-0.2-0.00.10.2-0.20.1-0.10.10.10.10.50.2-0.6-0.5-0.10.30.00.0
Patch foraging indifference point AUC0.30.81.5-1.11.2-1.21.0-1.21.0-1.0-1.0-1.01.21.10.9-0.81.00.90.8-0.1-0.0-0.30.20.00.0
Delay disc. indifference point, 0s delay2.12.48.9-1.21.6-0.52.1-0.60.9-1.6-1.8-1.20.40.51.1-1.2-0.7-1.9-0.83.03.01.4-1.5-1.02.3
Delay disc. indifference point, 16s delay0.60.93.10.80.21.0-0.21.2-0.90.80.71.3-0.8-1.0-0.71.1-1.0-0.2-1.7-0.6-0.51.7-1.30.10.4
Delay disc. indifference point, 2s delay1.92.17.91.0-0.41.5-0.11.3-1.20.70.40.9-1.5-1.1-0.91.2-2.4-1.9-2.21.10.92.8-2.50.80.8
Delay disc. indifference point, 24s delay0.71.12.31.0-0.41.1-0.61.2-1.31.01.01.4-1.1-1.2-1.01.3-1.4-0.6-1.5-0.3-0.31.4-1.20.6-0.1
Delay disc. indifference point, 4s delay1.31.44.30.70.11.10.21.1-1.10.40.30.7-1.1-1.1-1.20.6-2.1-1.5-2.11.21.01.6-2.00.40.8
Delay disc. indifference point, 8s delay0.91.44.11.00.11.0-0.41.3-1.31.11.11.4-1.0-1.3-1.41.5-1.5-0.0-2.0-0.8-0.91.9-2.00.10.3
Indifference point function ln k0.10.42.6-0.10.1-0.4-0.2-0.40.10.20.20.10.30.3-0.00.50.51.50.4-1.4-1.60.1-0.20.00.0
Indifference point function log k0.10.42.6-0.10.1-0.4-0.2-0.40.10.20.20.10.30.3-0.00.50.51.50.4-1.4-1.60.1-0.20.00.0
Patch foraging total patch changes 0 sec0.00.10.80.3-0.3-0.1-0.5-0.1-0.20.40.4-0.0-0.0-0.2-0.20.40.10.60.2-0.9-0.8-0.10.30.00.0
Patch foraging total patch changes 12 sec0.10.20.4-0.50.6-0.50.5-0.40.4-0.5-0.4-0.40.50.20.4-0.60.20.30.10.20.2-0.30.30.00.0
Patch foraging total patch changes 18 sec0.00.10.50.10.1-0.2-0.1-0.0-0.10.20.30.20.2-0.2-0.30.10.10.40.0-0.7-0.5-0.30.10.00.0
Patch foraging total patch changes 24 sec0.10.53.30.4-0.1-0.2-0.60.0-0.40.70.80.50.2-0.4-0.70.70.31.30.1-1.8-1.6-0.30.20.00.0
Patch foraging total patch changes 6 sec0.10.10.4-0.30.4-0.60.2-0.60.3-0.2-0.2-0.50.50.30.3-0.20.40.60.3-0.4-0.2-0.10.40.00.0
Patch foraging time to switch 0 sec0.62.312.50.6-0.61.50.21.4-0.4-0.2-0.30.2-1.3-1.2-0.1-0.9-1.6-3.5-1.43.53.50.20.10.00.0
Patch foraging water rate 0 sec0.93.413.8-1.71.7-2.51.0-2.51.5-1.0-1.0-1.42.32.11.2-0.32.33.71.9-2.6-2.7-0.4-0.00.00.0
Patch foraging water rate 12 sec0.20.74.2-0.40.6-0.9-0.0-0.80.20.10.20.00.80.6-0.30.50.82.00.6-1.7-1.9-0.1-0.40.00.0
Patch foraging water rate 18 sec0.40.83.90.8-0.80.3-1.20.2-0.71.11.11.0-0.4-0.5-0.81.40.01.10.0-1.8-2.00.5-0.30.00.0
Patch foraging water rate 24 sec1.21.75.9-1.51.7-1.91.2-1.71.3-1.1-1.0-1.01.81.60.9-0.51.52.41.1-1.1-1.4-0.2-0.40.00.0
Patch foraging water rate 6 sec0.40.63.2-0.70.7-1.10.3-1.00.4-0.3-0.2-0.31.00.90.10.00.91.80.8-1.2-1.4-0.3-0.20.00.0
Seeking ratio, delayed vs. immediate footshock1.11.54.01.3-1.41.3-1.51.4-1.21.21.31.3-1.1-1.3-1.30.3-0.5-1.1-0.20.30.6-1.41.41.7-2.0
Distance traveled before self-admin0.10.31.30.4-0.80.7-0.30.4-0.10.2-0.00.3-0.60.20.00.4-0.4-1.1-0.10.40.51.0-0.70.6-0.1
Distance traveled after self-admin0.20.31.90.5-0.40.4-0.60.5-0.50.60.60.5-0.4-0.1-0.30.8-0.20.7-0.4-1.2-1.40.5-0.30.1-0.2
Extensor digitorum longus weight3.112.520.8-4.54.4-4.54.3-4.54.3-4.2-4.2-4.34.64.64.2-3.43.53.42.80.60.0-0.70.40.00.0
Bone: elastic displacement0.20.21.2-0.40.5-0.70.2-0.60.3-0.2-0.1-0.20.60.40.20.00.61.10.4-0.9-0.9-0.20.00.00.0
Bone: elastic work2.33.05.5-2.22.3-2.42.1-2.22.1-2.0-1.9-2.02.32.11.9-1.51.91.91.3-0.2-0.3-0.40.10.00.0
Bone: endosteal estimation0.20.51.1-0.80.9-0.90.7-0.90.8-0.7-0.6-0.70.90.90.6-0.50.81.10.6-0.4-0.4-0.20.10.00.0
Bone: endosteal perimeter0.10.31.8-0.00.2-0.3-0.2-0.2-0.10.30.30.20.30.2-0.20.40.41.30.2-1.3-1.3-0.20.10.00.0
Epididymis fat weight0.00.00.10.1-0.00.30.00.4-0.20.10.10.0-0.3-0.2-0.2-0.2-0.3-0.3-0.30.30.3-0.30.10.00.0
Delta time in closed arm before/after self-admin0.30.31.4-0.50.9-0.40.8-0.30.4-0.5-0.5-0.30.30.30.3-0.1-0.10.4-0.50.0-0.10.7-0.8-0.81.2
Delta time in open arm before/after self-admin2.12.55.71.9-2.42.0-2.21.6-1.71.71.71.6-1.9-1.3-1.41.5-1.3-1.2-0.6-0.4-0.40.20.22.2-2.1
Diff in mean of infusions in LGA sessions0.10.10.4-0.40.4-0.40.2-0.30.4-0.2-0.2-0.30.30.20.3-0.10.60.60.4-0.4-0.3-0.10.2-0.40.2
Delay discount exponential model param2.02.68.3-1.30.1-1.70.3-1.81.7-1.2-1.1-1.71.61.71.5-1.82.41.02.90.00.2-2.92.7-0.5-0.7
Extinction: sum of active levers before priming0.50.81.60.8-0.50.8-0.61.0-1.10.90.91.0-0.9-1.0-1.11.2-1.1-0.3-1.3-0.6-0.61.0-1.20.5-0.2
Active lever presses in extinction session 60.10.10.3-0.20.0-0.40.1-0.50.1-0.2-0.1-0.40.40.40.4-0.10.20.30.5-0.5-0.4-0.30.3-0.3-0.1
Bone: final force0.91.52.6-1.51.5-1.41.6-1.41.5-1.5-1.5-1.61.41.41.6-1.31.10.70.80.60.6-0.10.20.00.0
Bone: final moment0.60.91.7-1.31.3-1.11.3-1.11.2-1.2-1.2-1.31.11.21.3-1.10.90.60.60.50.5-0.10.20.00.0
Food consumed during 24 hour testing period0.00.10.20.3-0.40.2-0.40.2-0.30.30.40.2-0.2-0.2-0.40.2-0.20.2-0.0-0.3-0.5-0.20.10.00.0
Glucose1.01.53.21.5-1.71.7-1.41.6-1.41.31.21.3-1.7-1.5-1.31.0-1.4-1.8-1.00.50.60.4-0.20.00.0
Heart weight0.40.63.5-0.2-0.2-0.6-0.4-0.80.30.10.1-0.30.50.90.40.40.91.51.1-1.9-1.7-0.30.40.00.0
Delay discount hyperbolic model param1.82.37.7-1.20.1-1.50.2-1.61.5-1.1-0.9-1.51.51.61.4-1.62.31.02.7-0.20.0-2.82.6-0.4-0.8
Intermittent access intake day 1-15 change0.31.74.2-1.31.1-1.60.8-1.41.3-1.1-0.9-1.31.61.31.3-1.21.72.11.5-0.3-0.7-1.51.5-1.20.3
Intermittent access intake escalation0.31.53.6-1.21.2-1.50.8-1.41.1-1.1-0.9-1.21.51.11.3-1.21.51.91.3-0.2-0.5-1.51.4-1.20.3
Intermittent access intake escalation 20.20.31.4-0.1-0.1-0.4-0.4-0.4-0.10.00.2-0.20.30.00.2-0.10.41.20.5-0.4-0.8-1.10.90.1-0.6
Intermitt. access day 1 inactive lever presses0.00.20.7-0.20.2-0.5-0.1-0.40.2-0.00.1-0.30.4-0.1-0.2-0.20.80.70.7-0.3-0.2-0.80.9-0.1-0.5
Intermitt. access day 15 inactive lever presses0.10.84.3-0.1-0.50.30.10.10.5-0.5-0.5-0.8-0.2-0.30.2-1.10.1-1.60.32.12.1-0.91.10.8-0.4
Intermitt. access escalation Index0.10.31.10.4-0.10.3-0.20.3-0.40.50.40.6-0.3-0.4-0.50.8-0.30.1-0.5-0.8-0.71.0-0.90.00.1
Intermittent access day 1 total infusions0.30.91.60.9-0.41.0-0.51.2-0.71.00.91.3-0.8-0.8-1.11.1-0.7-0.1-1.2-1.2-1.01.3-1.20.2-0.0
Intermittent access day 15 total infusions0.10.31.6-0.10.5-0.20.10.00.20.10.20.20.40.1-0.10.10.31.3-0.2-1.1-1.20.2-0.2-0.70.3
Intermittent access terminal intake (last 3 days)0.10.10.80.10.30.0-0.00.2-0.10.20.20.30.1-0.2-0.20.3-0.10.8-0.5-0.7-0.90.3-0.3-0.30.2
Intermittent access total infusions0.20.21.20.20.30.40.20.5-0.10.20.20.4-0.2-0.4-0.40.4-0.40.0-1.0-0.4-0.31.1-0.9-0.30.6
Intermittent access day 1 locomotion0.51.02.90.9-0.41.0-0.41.1-0.90.90.81.1-0.9-0.9-1.11.2-1.1-0.6-1.5-0.8-0.61.7-1.60.40.2
Intermittent access day 15 total locomotion0.10.52.8-0.30.6-0.50.2-0.40.3-0.00.0-0.30.60.5-0.10.30.51.70.0-1.5-1.60.3-0.5-0.80.4
Intermittent access total locomotion0.40.51.30.50.00.6-0.20.7-0.40.60.60.7-0.4-0.5-0.70.8-0.60.3-1.1-1.0-0.91.2-1.1-0.10.3
Intermittent access standard deviation0.20.93.0-0.80.1-0.70.3-0.81.0-0.9-0.9-1.20.70.71.3-1.31.10.21.21.20.9-1.51.7-0.0-0.2
Left kidney weight4.435.660.5-7.67.8-7.57.6-7.47.5-7.5-7.4-7.47.47.07.1-6.45.74.54.22.41.7-1.20.60.00.0
Right kidney weight4.028.346.8-6.76.6-6.46.8-6.56.7-6.8-6.8-6.86.36.36.5-5.94.83.03.83.02.5-1.10.50.00.0
Cocaine induced anxiety0.00.10.80.10.40.30.20.4-0.00.00.10.2-0.2-0.4-0.10.1-0.40.1-0.90.1-0.10.7-0.6-0.40.5
Post-drug Anxiety2.12.47.11.1-0.51.9-0.11.8-1.10.60.51.0-1.7-1.9-1.00.6-2.5-2.5-2.71.91.71.9-1.80.90.5
Baseline Anxiety1.42.310.01.3-1.21.8-0.51.7-1.20.70.51.0-1.8-1.6-0.90.4-2.2-3.2-1.82.02.11.0-1.01.7-0.2
Tail length4.825.742.5-6.56.3-6.36.4-6.46.4-6.4-6.4-6.56.16.06.0-5.34.83.23.82.52.1-0.90.40.00.0
Length with tail13.459.497.3-9.99.8-9.69.7-9.79.7-9.7-9.7-9.79.49.19.1-8.17.45.45.73.52.6-1.40.60.00.0
Length without tail5.126.944.9-6.66.4-6.66.5-6.76.6-6.5-6.5-6.76.36.06.2-5.44.93.73.92.31.6-1.00.40.00.0
Times rat made contact with spout0.10.10.5-0.30.3-0.40.2-0.30.2-0.2-0.1-0.30.40.30.0-0.20.30.70.3-0.4-0.5-0.40.20.00.0
Lifetime Intake0.30.31.40.5-0.10.6-0.00.7-0.30.40.30.5-0.5-0.7-0.60.5-0.6-0.5-1.1-0.10.01.2-1.00.10.3
Liver weight, left1.93.36.2-2.32.3-2.52.1-2.52.2-2.1-2.1-2.22.42.22.0-1.61.91.91.5-0.0-0.1-0.30.20.00.0
Liver weight, right1.73.05.1-2.22.3-2.22.2-2.12.2-2.2-2.1-2.22.21.81.9-1.91.61.31.10.80.5-0.40.10.00.0
Locomotor activity1.21.88.3-1.11.2-1.70.5-1.61.0-0.5-0.5-0.81.71.50.8-0.01.72.91.4-2.4-2.3-0.40.10.00.0
Locomotor testing distance0.51.25.7-0.80.9-1.30.4-1.20.7-0.3-0.3-0.51.31.30.30.11.42.41.1-2.0-2.0-0.2-0.10.00.0
Locomotor testing rearing0.10.31.8-0.20.5-0.50.1-0.40.20.00.10.10.60.6-0.00.20.71.30.4-1.4-1.2-0.00.00.00.0
Locomotion in novel chamber1.11.54.1-1.31.3-1.21.0-1.11.5-1.0-1.0-1.01.41.41.4-0.91.72.01.1-0.6-0.9-0.30.9-1.50.9
Locomotion in novel chamber post-restriction0.72.17.3-1.41.6-1.91.1-1.71.3-0.9-0.8-1.01.71.61.0-0.51.42.71.0-1.7-2.0-0.3-0.0-2.01.2
Fecal boli incidents, locomotor time 10.71.83.5-1.51.8-1.91.5-1.81.3-1.3-1.2-1.51.71.41.0-0.81.01.70.8-0.4-0.5-0.1-0.2-1.81.5
Change in fecal boli incidents, locomotor task0.20.31.20.3-0.40.6-0.10.6-0.30.10.10.4-0.5-0.2-0.3-0.1-0.4-1.1-0.41.10.9-0.1-0.10.6-0.2
Time >=10cm from walls, locomotor time 11.62.04.61.3-0.81.7-0.61.7-1.41.10.92.1-1.6-1.6-1.31.1-1.8-2.1-1.90.81.01.6-1.61.1-0.1
Bouts of movement, locomotor time 10.60.82.5-1.01.6-1.01.1-0.80.6-0.8-0.7-1.01.10.50.8-0.60.51.60.1-0.4-0.6-0.10.3-1.51.2
Total resting periods, locomotor time 10.60.72.4-0.91.5-0.91.1-0.70.6-0.8-0.6-0.81.00.50.8-0.60.41.50.0-0.4-0.6-0.10.2-1.41.2
Rest time, locomotor task time 10.81.22.5-1.41.6-1.21.4-1.11.1-1.4-1.3-1.11.20.91.2-1.30.80.90.50.90.5-0.60.4-1.31.2
Distance moved, locomotor task time 10.30.71.50.9-0.90.9-0.80.7-0.80.90.80.6-0.9-0.6-0.81.2-1.0-0.3-0.9-1.0-0.91.1-1.00.7-0.2
Vertical activity count, locomotor time 10.10.53.20.30.10.1-0.20.2-0.20.50.50.3-0.00.0-0.20.8-0.11.0-0.6-1.8-1.70.9-0.7-0.40.3
Time >=10cm from walls, locomotor time 20.41.13.9-1.01.1-0.51.5-0.50.9-1.3-1.3-0.50.50.61.0-1.1-0.2-0.9-0.22.01.70.6-0.7-0.81.6
Bouts of movement, locomotor time 20.31.12.1-1.21.3-1.21.1-1.01.1-1.0-0.9-1.11.11.11.3-0.81.01.50.7-0.3-0.6-0.40.3-1.41.1
Total resting periods, locomotor time 20.31.01.9-1.21.2-1.11.1-1.01.1-1.1-1.0-1.11.11.11.4-1.01.01.20.80.0-0.3-0.60.6-1.30.9
Rest time, locomotor task time 20.10.10.30.3-0.30.3-0.40.3-0.40.30.30.5-0.3-0.5-0.30.3-0.2-0.1-0.30.2-0.0-0.00.00.4-0.5
Distance moved, locomotor task time 20.10.10.5-0.2-0.1-0.3-0.0-0.40.3-0.2-0.2-0.70.20.30.3-0.20.20.50.4-0.5-0.4-0.40.4-0.10.2
Vertical activity count, locomotor time 20.61.32.9-1.21.2-1.50.9-1.41.2-0.9-0.8-1.41.41.41.0-0.71.21.71.1-0.9-0.8-0.50.7-1.40.9
Light reinforcement 10.41.93.41.8-1.81.7-1.81.6-1.51.71.71.8-1.6-1.6-1.71.4-1.2-0.7-0.9-0.7-0.70.40.10.00.0
Light reinforcement 20.00.00.10.10.10.1-0.10.2-0.00.10.20.4-0.1-0.2-0.3-0.0-0.10.2-0.20.1-0.10.10.20.00.0
Bone: marrow area0.20.41.1-0.80.9-0.90.7-0.80.7-0.6-0.6-0.70.90.90.6-0.50.81.00.6-0.4-0.4-0.20.10.00.0
Bone: maximum diameter0.20.30.6-0.70.7-0.70.6-0.70.7-0.6-0.6-0.80.70.70.7-0.50.60.70.5-0.1-0.1-0.10.10.00.0
Bone: maximum force0.51.01.8-1.31.2-1.11.2-1.21.3-1.2-1.2-1.31.11.31.3-1.01.00.70.80.30.3-0.10.20.00.0
Bone: maximum moment0.40.71.2-1.11.0-0.91.0-1.01.1-1.0-1.0-1.11.01.11.0-0.80.90.70.70.10.1-0.10.10.00.0
Mean time between licks in bursts0.21.32.51.4-1.41.3-1.41.3-1.51.51.51.6-1.3-1.2-1.41.4-1.0-0.7-0.7-0.8-0.50.3-0.30.00.0
Mean num. licks in bursts0.00.00.2-0.30.4-0.20.3-0.10.3-0.3-0.2-0.20.30.20.1-0.30.20.20.00.00.1-0.1-0.00.00.0
Cd content in liver1.21.38.00.8-0.70.3-1.20.4-0.81.21.30.9-0.4-0.2-0.81.50.22.00.1-2.5-2.80.1-0.10.00.0
Co content in liver1.51.85.1-1.61.9-1.51.5-1.41.4-1.3-1.3-1.21.61.81.6-0.91.52.30.9-0.7-1.0-0.20.20.00.0
Cu content in liver0.00.00.10.10.00.2-0.00.3-0.30.10.10.1-0.2-0.2-0.2-0.0-0.3-0.3-0.30.30.3-0.1-0.10.00.0
Fe content in liver0.10.10.70.1-0.2-0.3-0.3-0.3-0.00.20.2-0.10.1-0.1-0.30.40.30.50.3-0.9-0.7-0.1-0.20.00.0
K content in liver0.10.10.7-0.0-0.20.20.1-0.00.2-0.2-0.2-0.3-0.0-0.10.2-0.2-0.1-0.8-0.00.60.80.20.10.00.0
Mg content in liver0.20.30.7-0.60.5-0.50.6-0.60.7-0.7-0.7-0.80.60.40.7-0.60.3-0.10.30.60.60.10.10.00.0
Mn content in liver0.30.30.70.7-0.80.7-0.70.6-0.70.70.70.5-0.7-0.8-0.80.6-0.6-0.4-0.5-0.1-0.10.1-0.10.00.0
Na content in liver0.30.40.7-0.70.6-0.60.7-0.80.8-0.8-0.9-0.90.60.60.8-0.70.4-0.10.40.70.70.10.10.00.0
Rb content in liver3.33.96.62.5-2.52.6-2.42.5-2.52.42.42.3-2.5-2.5-2.31.9-2.0-1.9-1.5-0.4-0.10.4-0.20.00.0
Se content in liver0.91.12.2-1.21.2-1.11.4-1.11.2-1.4-1.4-1.41.00.71.1-1.30.6-0.30.31.51.4-0.1-0.10.00.0
Sr content in liver0.10.10.40.1-0.1-0.1-0.2-0.1-0.00.20.3-0.00.1-0.2-0.20.30.20.50.1-0.6-0.60.10.10.00.0
Zn content in liver3.84.58.8-2.73.0-2.72.7-2.52.5-2.5-2.5-2.52.72.52.5-2.02.12.31.40.4-0.0-0.30.10.00.0
Bone: minimum diameter0.61.22.51.4-1.51.3-1.61.3-1.31.51.51.2-1.3-1.2-1.21.3-0.8-0.3-0.7-1.0-0.90.20.10.00.0
Time in familiar zone, hab. session 10.20.20.90.4-0.60.4-0.30.4-0.40.20.20.1-0.5-0.5-0.20.1-0.6-1.0-0.40.60.7-0.00.10.00.0
Time in novel zone, hab. session 10.30.30.8-0.70.4-0.60.6-0.90.8-0.7-0.8-0.80.60.80.8-0.50.60.20.70.30.30.20.00.00.0
Total zone transitions, hab. session 12.53.66.72.4-2.52.2-2.62.2-2.32.52.52.2-2.2-2.1-2.32.2-1.5-0.7-1.1-1.5-1.30.3-0.10.00.0
Total locomotion distance, hab. session 10.81.23.11.4-1.81.4-1.51.2-1.31.31.21.0-1.4-1.1-1.11.2-1.1-1.1-0.6-0.2-0.10.4-0.10.00.0
Locomotion velocity, hab. session 11.62.33.92.0-2.01.9-1.91.9-1.81.91.91.8-1.8-1.8-1.91.7-1.4-1.0-1.1-0.7-0.60.4-0.20.00.0
Time in familiar zone, hab. session 20.20.31.3-0.50.4-0.40.6-0.30.4-0.6-0.6-0.50.20.20.4-0.7-0.1-0.7-0.01.21.1-0.20.00.00.0
Time in novel zone, hab. session 20.70.81.61.1-1.11.0-1.30.9-1.01.21.21.0-0.9-0.8-1.01.2-0.40.2-0.3-1.2-1.20.3-0.00.00.0
Total zone transitions, hab. session 20.20.20.80.5-0.50.1-0.60.2-0.40.60.60.4-0.2-0.3-0.40.6-0.10.4-0.0-0.9-0.90.00.00.00.0
Total locomotion distance, hab. session 20.50.61.31.0-1.10.8-1.10.8-0.91.11.00.8-0.8-0.8-0.91.0-0.6-0.2-0.4-0.8-0.70.2-0.10.00.0
Locomotion velocity, hab. session 20.40.61.41.0-1.20.9-1.10.8-0.91.01.00.8-0.8-0.8-0.91.0-0.6-0.3-0.4-0.7-0.60.2-0.10.00.0
Novel to familiar place preference ratio0.00.00.00.1-0.10.2-0.10.1-0.00.10.10.1-0.00.10.00.10.10.10.0-0.2-0.20.1-0.00.00.0
Novelty place preference0.10.20.40.5-0.50.6-0.50.5-0.40.50.50.5-0.5-0.4-0.40.5-0.3-0.2-0.2-0.3-0.20.2-0.00.00.0
Time in novel zone, NPP test0.00.00.10.2-0.20.3-0.20.3-0.10.20.20.2-0.2-0.1-0.10.2-0.1-0.1-0.1-0.1-0.10.2-0.00.00.0
Total zone transitions, NPP test0.20.20.50.6-0.70.5-0.70.5-0.60.70.70.5-0.5-0.5-0.50.6-0.30.0-0.2-0.6-0.60.10.00.00.0
Total locomotion distance, NPP test0.30.40.80.8-0.90.9-0.80.8-0.80.70.70.6-0.8-0.7-0.70.6-0.7-0.6-0.5-0.10.00.2-0.10.00.0
Locomotion velocity, NPP test0.30.51.00.9-1.00.8-1.00.7-0.90.90.90.7-0.7-0.7-0.80.9-0.5-0.1-0.3-0.7-0.60.2-0.10.00.0
Intraocular pressure0.91.42.5-1.51.4-1.51.4-1.51.5-1.5-1.5-1.41.31.61.5-1.21.21.01.00.40.1-0.40.20.00.0
Delta distance traveled before/after self-admin0.50.52.80.20.1-0.2-0.50.1-0.40.50.70.30.2-0.3-0.40.30.31.70.0-1.5-1.7-0.90.7-0.2-0.6
Delta ambulatory time before/after self-admin0.50.92.70.9-0.70.5-1.20.8-1.01.11.30.9-0.6-0.9-0.90.8-0.31.0-0.4-1.4-1.6-0.70.60.7-1.2
Parametrial fat weight0.51.34.2-1.10.8-0.71.3-0.91.2-1.5-1.6-1.50.70.91.4-1.50.3-1.10.32.02.00.1-0.00.00.0
Pavlov. Cond. lever latency3.14.06.6-2.52.5-2.62.5-2.52.5-2.4-2.4-2.42.52.52.4-1.92.01.71.60.50.3-0.30.10.00.0
Pavlov. Cond. magazine entry latency0.00.00.2-0.30.3-0.20.2-0.10.2-0.2-0.1-0.10.20.30.2-0.10.30.50.1-0.3-0.3-0.10.10.00.0
Pavlov. Cond. change in total contacts1.01.12.21.1-1.11.4-0.91.5-1.21.01.01.2-1.4-1.3-1.10.6-1.3-1.5-1.10.60.70.0-0.10.00.0
Pavlov. Cond. index score0.30.40.80.7-0.60.8-0.70.9-0.80.70.70.8-0.8-0.8-0.70.5-0.6-0.5-0.6-0.1-0.1-0.0-0.00.00.0
Pavlov. Cond. latency score0.71.01.81.2-1.11.3-1.11.3-1.21.21.21.2-1.3-1.2-1.20.9-1.0-0.8-0.9-0.2-0.10.1-0.00.00.0
Pavlov. Cond. lever contacts2.83.45.92.3-2.32.4-2.22.4-2.32.22.22.2-2.4-2.3-2.21.7-1.9-1.6-1.5-0.3-0.20.3-0.10.00.0
Pavlov. Cond. magazine entry number0.00.10.40.0-0.10.10.1-0.10.0-0.1-0.1-0.2-0.0-0.10.1-0.1-0.2-0.6-0.00.60.60.2-0.00.00.0
Pavlov. Cond. intertrial magazine entries0.70.81.51.1-1.11.0-1.21.0-1.21.21.21.2-0.9-0.9-1.21.2-0.6-0.1-0.4-0.9-0.80.2-0.20.00.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.6-0.50.8-0.50.8-0.60.50.60.7-0.7-0.7-0.60.3-0.6-0.6-0.60.20.2-0.00.00.00.0
Pavlov. Cond. response bias0.10.10.20.3-0.20.4-0.30.4-0.30.30.30.4-0.3-0.3-0.30.2-0.2-0.0-0.2-0.2-0.2-0.0-0.00.00.0
Pavlov. Cond. lever latency0.30.40.7-0.80.7-0.80.7-0.80.8-0.7-0.8-0.80.70.80.8-0.50.70.60.60.0-0.1-0.10.00.00.0
Pavlov. Cond. magazine entry latency1.31.93.31.7-1.61.7-1.61.8-1.71.61.71.7-1.6-1.8-1.81.2-1.4-1.2-1.1-0.3-0.0-0.0-0.00.00.0
Pavlov. Cond. change in total contacts0.10.10.30.4-0.30.4-0.40.4-0.50.50.50.6-0.4-0.5-0.50.4-0.3-0.2-0.2-0.2-0.2-0.0-0.00.00.0
Pavlov. Cond. index score1.01.52.71.6-1.41.5-1.51.5-1.61.51.61.6-1.5-1.6-1.61.2-1.2-0.9-1.0-0.5-0.30.1-0.00.00.0
Pavlov. Cond. latency score0.71.12.01.3-1.21.3-1.21.4-1.31.31.31.4-1.3-1.4-1.40.9-1.1-0.9-0.9-0.2-0.00.0-0.10.00.0
Pavlov. Cond. lever contacts0.40.61.11.0-0.91.0-0.91.0-1.01.01.01.1-1.0-1.0-1.00.7-0.8-0.6-0.6-0.2-0.10.1-0.10.00.0
Pavlov. Cond. magazine entry number1.01.32.5-1.41.2-1.41.4-1.41.5-1.4-1.5-1.61.31.41.6-1.11.10.80.90.50.20.10.10.00.0
Pavlov. Cond. intertrial magazine entries0.10.21.2-0.20.1-0.3-0.1-0.40.20.00.0-0.20.30.40.20.30.51.00.4-0.9-1.10.2-0.00.00.0
Pavlov. Cond. lever-magazine prob. diff.1.11.73.01.6-1.51.5-1.61.6-1.61.61.71.7-1.5-1.6-1.71.3-1.2-0.8-1.0-0.6-0.40.1-0.10.00.0
Pavlov. Cond. response bias0.91.22.11.4-1.31.4-1.41.4-1.41.41.41.4-1.3-1.3-1.41.1-1.0-0.7-0.8-0.6-0.40.1-0.00.00.0
Time in closed arm before self-admin1.01.83.0-1.31.2-1.71.0-1.71.3-1.0-1.0-1.21.71.71.4-0.91.61.71.6-1.1-0.9-0.90.9-1.50.7
Time in closed arm after self-admin1.51.84.4-1.41.6-1.71.2-1.61.2-1.0-1.0-1.21.71.51.2-0.61.42.10.9-1.2-1.3-0.20.0-1.91.3
Time in open arm before self-admin0.20.31.80.00.40.10.30.1-0.30.00.00.1-0.1-0.3-0.30.5-0.60.1-0.90.1-0.21.1-1.3-0.40.7
Time in open arm after self-admin1.01.12.21.2-1.51.4-1.21.1-1.11.00.90.9-1.4-0.9-0.80.9-1.2-1.1-0.70.40.10.6-0.31.4-1.1
Bone: periosteal estimation0.20.61.0-0.90.9-0.90.8-0.90.9-0.8-0.8-1.00.91.00.9-0.60.90.90.7-0.2-0.3-0.10.10.00.0
Bone: periosteal perimeter0.20.31.90.4-0.40.2-0.60.3-0.50.70.70.4-0.2-0.2-0.50.70.10.9-0.0-1.4-1.3-0.10.10.00.0
Bone: post-yield work0.10.10.5-0.40.3-0.40.3-0.50.5-0.4-0.4-0.40.40.70.4-0.20.50.50.5-0.2-0.3-0.0-0.00.00.0
Progressive ratio test 1 active lever presses0.81.43.0-1.41.6-1.21.6-1.11.4-1.3-1.3-1.21.41.21.1-0.90.90.90.4-0.00.00.4-0.6-1.71.6
Progressive ratio test 1 breakpoint0.81.32.9-1.41.6-1.21.6-1.11.3-1.3-1.3-1.21.41.21.1-0.90.90.80.40.00.00.4-0.6-1.71.6
Progressive ratio test 1 inactive lever presses0.41.02.8-1.10.8-1.10.7-1.11.3-0.8-0.8-0.91.21.21.0-0.81.71.41.3-0.6-0.6-0.80.9-1.10.4
Progressive ratio test 2 active lever presses0.60.92.5-0.91.3-1.11.0-0.90.8-0.6-0.6-0.71.20.80.5-0.30.91.60.3-1.0-1.00.2-0.4-1.51.0
Progressive ratio test 2 breakpoint0.60.72.5-0.81.2-1.00.9-0.80.7-0.5-0.5-0.61.10.70.4-0.20.71.60.2-1.1-1.10.2-0.4-1.41.0
Progressive ratio test 2 inactive lever presses1.03.16.8-1.91.7-2.31.3-2.22.0-1.5-1.4-2.12.31.81.5-1.32.52.62.0-0.9-1.0-1.11.0-2.00.8
Incentive Sensitization - Responses0.10.20.70.4-0.20.2-0.40.3-0.50.50.60.5-0.2-0.4-0.60.5-0.20.5-0.3-0.9-0.80.1-0.00.1-0.3
Incentive Sensitization - Breakpoint0.10.31.00.5-0.30.3-0.60.4-0.60.70.70.6-0.3-0.5-0.70.6-0.30.5-0.4-1.0-1.00.1-0.10.2-0.5
Sum of active levers in priming session hrs 5-60.20.21.1-0.20.2-0.00.5-0.10.3-0.4-0.5-0.40.1-0.10.6-0.4-0.3-0.7-0.31.00.90.3-0.1-0.10.5
Progressive ratio0.20.52.10.5-0.40.9-0.20.9-0.80.20.20.4-0.7-0.4-0.5-0.2-1.0-1.4-0.51.21.4-0.20.10.7-0.4
Food seeking constrained by brief footshock1.51.96.21.4-1.91.1-1.91.2-1.11.31.51.0-1.1-1.3-1.20.3-0.1-0.60.3-0.1-0.0-1.92.12.0-2.5
Seeking ratio, punishment vs. effort0.20.51.7-0.40.1-0.9-0.1-0.70.7-0.1-0.1-0.30.60.30.4-0.21.21.30.8-0.9-1.1-0.90.9-0.3-0.3
Retroperitoneal fat weight0.10.74.10.1-0.20.60.30.6-0.0-0.3-0.4-0.2-0.6-0.50.1-0.7-0.7-1.9-0.72.02.00.1-0.10.00.0
Reaction time number correct0.20.62.6-0.70.9-1.00.5-0.90.5-0.4-0.3-0.40.91.00.4-0.10.81.60.7-1.1-1.2-0.2-0.10.00.0
Reaction time mean minus median0.00.20.40.5-0.30.5-0.40.7-0.50.60.60.6-0.4-0.5-0.50.3-0.3-0.0-0.4-0.6-0.4-0.20.20.00.0
Reaction time mean minus median AUC0.10.71.31.0-0.80.9-1.01.0-1.01.11.11.0-0.8-0.8-0.90.8-0.50.1-0.6-1.1-1.0-0.20.20.00.0
Reaction time num false alarms0.10.21.10.4-0.60.3-0.70.2-0.50.60.60.3-0.2-0.1-0.60.7-0.00.40.2-1.0-1.0-0.1-0.10.00.0
Reaction time num false alarms AUC0.10.10.80.1-0.3-0.1-0.4-0.3-0.10.20.2-0.20.10.3-0.10.30.30.50.5-0.9-0.8-0.20.10.00.0
Reaction time trials correct on left0.20.62.6-0.70.9-1.00.5-0.90.5-0.4-0.3-0.40.91.00.4-0.10.81.60.7-1.1-1.2-0.2-0.10.00.0
Reaction time trials on left0.20.52.6-0.70.8-1.00.4-0.80.5-0.4-0.3-0.40.90.90.4-0.10.81.60.7-1.1-1.2-0.3-0.00.00.0
Reaction time mean0.91.94.11.7-1.61.9-1.52.0-1.81.61.61.6-1.7-1.9-1.71.0-1.3-1.5-1.3-0.10.2-0.20.10.00.0
Reaction time mean AUC0.71.73.71.6-1.51.8-1.41.9-1.71.51.61.6-1.6-1.7-1.71.0-1.2-1.3-1.2-0.30.0-0.2-0.00.00.0
Median of all reaction times1.62.45.11.9-1.82.1-1.62.2-1.91.71.71.8-2.0-2.1-1.91.1-1.6-1.9-1.40.20.5-0.10.00.00.0
Reaction time omissions0.30.41.40.5-0.30.8-0.20.9-0.90.40.40.7-0.7-0.8-0.60.1-1.0-1.2-0.90.80.90.0-0.30.00.0
Reaction time false alarm rate0.10.10.40.4-0.60.3-0.50.2-0.30.40.30.1-0.3-0.2-0.40.4-0.1-0.20.1-0.3-0.2-0.10.10.00.0
Reaction time premature initiation rate0.00.00.20.1-0.40.1-0.2-0.2-0.00.0-0.1-0.1-0.2-0.10.30.2-0.1-0.40.10.40.30.40.00.00.0
Reaction time premature initiations0.00.10.3-0.20.1-0.40.1-0.50.2-0.2-0.2-0.30.20.30.40.10.20.30.4-0.0-0.20.2-0.00.00.0
Std. dev. reaction times0.30.91.91.2-1.01.2-1.01.4-1.21.11.11.2-1.1-1.3-1.00.7-0.9-0.8-0.9-0.30.0-0.10.20.00.0
Reaction time trials completed0.20.52.6-0.70.8-1.00.4-0.80.5-0.4-0.3-0.40.90.90.4-0.10.81.60.7-1.1-1.2-0.3-0.00.00.0
Reaction time trials AUC0.10.42.5-0.40.6-0.80.1-0.60.2-0.10.0-0.10.70.70.20.20.61.60.5-1.3-1.4-0.2-0.00.00.0
Run reversals in cocaine runway, females0.70.81.41.0-1.11.1-1.11.1-1.01.01.01.0-1.0-0.9-1.10.6-0.7-0.4-0.40.1-0.2-0.20.21.2-1.2
Run reversals in cocaine runway, males0.70.84.60.5-0.50.1-0.90.2-0.30.91.00.5-0.2-0.3-0.61.00.51.40.2-2.1-2.0-0.20.20.1-0.9
Latency to leave start box in cocaine runway0.20.31.8-0.10.10.30.40.2-0.4-0.3-0.3-0.1-0.20.0-0.1-0.3-0.7-1.0-0.31.31.20.3-0.70.10.3
Latency to leave start box in cocaine runway, F0.70.83.9-0.90.6-0.51.0-0.60.6-1.1-1.1-1.10.50.60.7-1.30.2-0.80.52.01.8-0.60.2-0.30.5
Latency to leave start box in cocaine runway, M0.60.61.30.8-0.40.8-0.50.8-1.10.80.81.0-0.7-0.5-0.81.0-1.1-0.1-0.9-0.6-0.71.0-1.10.3-0.1
Std. dev. time between licks in bursts0.10.31.0-0.50.6-0.70.4-0.70.5-0.4-0.3-0.30.60.70.4-0.20.61.00.5-0.6-0.7-0.1-0.00.00.0
Total sessions with >9 infusions0.10.21.20.1-0.20.30.10.20.2-0.1-0.2-0.2-0.2-0.30.1-0.3-0.1-1.1-0.20.81.10.20.00.30.0
Short access day 1 total inactive lever presses0.20.51.6-0.60.4-0.40.6-0.30.7-0.7-0.6-0.70.60.30.5-1.20.8-0.50.61.01.2-1.11.0-0.20.0
Short access day 10 total inactive lever presses0.53.46.2-1.81.0-1.91.3-1.92.1-1.9-1.8-2.11.81.72.0-2.52.20.32.41.61.7-2.42.4-0.90.3
Short access day 1 total infusions0.50.93.71.0-1.11.3-0.71.2-0.80.80.70.9-1.1-1.1-0.90.4-0.8-1.9-0.70.71.10.3-0.01.3-0.9
Short access day 10 total infusions0.20.30.80.7-0.60.8-0.50.9-0.40.60.60.7-0.6-0.9-0.60.4-0.4-0.7-0.7-0.00.10.3-0.20.6-0.4
Short access total infusions0.60.83.90.8-0.81.1-0.31.0-0.40.50.30.5-1.0-1.1-0.70.3-0.8-2.0-1.01.01.30.9-0.50.9-0.2
Short access day 1 locomotion0.40.62.20.50.20.70.10.9-0.60.40.40.7-0.6-0.8-0.70.7-1.0-0.6-1.5-0.10.01.5-1.5-0.10.6
Short access day 10 total locomotion0.00.10.9-0.1-0.20.0-0.10.10.3-0.1-0.10.00.10.00.2-0.40.6-0.10.50.20.3-0.70.90.2-0.4
Short access total locomotion0.40.61.50.7-0.41.0-0.21.0-0.60.50.40.7-0.8-1.0-0.70.5-0.9-1.2-1.20.40.51.1-1.00.50.1
One hour access (0.3 mA shock)1.11.37.9-0.20.5-0.8-0.2-0.50.20.40.50.10.90.4-0.40.51.32.80.6-2.7-2.7-0.40.3-1.0-0.3
Compulsive drug intake1.92.95.22.0-1.91.7-2.11.7-2.12.02.11.7-1.9-2.1-2.31.8-1.4-0.7-1.0-0.7-0.60.1-0.12.1-2.0
One hour access (shock baseline)0.71.94.7-1.41.8-1.51.4-1.31.4-1.1-1.0-0.91.71.51.1-0.61.42.20.5-1.2-1.40.4-0.6-2.21.6
Social response proportion3.44.38.7-2.73.0-2.62.9-2.42.5-2.6-2.6-2.22.62.52.3-2.22.01.41.40.90.8-0.3-0.10.00.0
Social responses1.52.05.1-1.72.0-1.91.5-1.71.7-1.3-1.3-1.21.91.81.4-1.01.82.31.2-1.0-1.0-0.20.10.00.0
Social time1.92.95.12.1-2.12.0-2.12.1-2.22.22.32.0-2.0-2.1-2.21.9-1.5-1.0-1.1-1.1-0.80.2-0.20.00.0
Soleus weight1.02.84.9-2.12.1-2.11.9-2.12.0-1.9-1.9-2.02.12.21.9-1.61.82.01.4-0.0-0.4-0.50.30.00.0
Bone: stiffness0.10.10.3-0.40.3-0.30.4-0.30.5-0.4-0.5-0.60.30.50.5-0.40.40.20.30.10.2-0.00.10.00.0
Tibialis anterior weight4.013.924.3-4.84.9-4.64.9-4.54.6-4.7-4.7-4.44.64.54.5-4.13.42.72.61.71.2-0.70.30.00.0
Time to tail flick, vehicle, before self-admin1.11.33.70.7-0.11.10.11.1-0.90.50.40.8-1.1-1.2-1.10.7-1.8-1.8-1.91.01.11.9-1.90.50.7
Time to tail flick, vehicle, after self-admin0.00.10.40.10.20.10.10.2-0.40.20.20.5-0.1-0.1-0.30.3-0.40.2-0.5-0.2-0.40.4-0.6-0.20.3
Time to tail flick, test, before self-admin0.91.01.8-1.31.2-1.21.1-1.11.2-1.1-1.1-1.11.41.20.8-0.91.31.10.80.10.0-0.30.1-1.30.9
Time to tail flick, test, after self-admin0.20.21.00.10.00.40.20.30.0-0.2-0.2-0.0-0.3-0.3-0.1-0.1-0.6-0.7-0.71.00.80.6-0.50.20.4
Delta time to tail flick, vehicle, before/after SA0.30.31.60.3-0.40.1-0.70.1-0.40.50.50.5-0.00.0-0.20.50.31.00.3-1.1-1.3-0.50.50.2-0.7
Delta time to tail flick, test, before/after SA0.70.91.71.2-1.11.3-1.01.2-1.10.90.91.0-1.2-1.2-0.90.6-1.1-1.1-0.90.30.30.10.11.2-0.9
Tibia length3.910.920.1-4.24.1-3.74.5-3.74.1-4.4-4.4-4.23.73.64.2-3.92.51.01.92.92.5-0.50.20.00.0
Ambulatory time before self-admin0.00.10.9-0.0-0.30.20.1-0.00.2-0.1-0.3-0.0-0.20.50.30.20.0-0.50.10.20.21.0-0.70.00.3
Ambulatory time after self-admin0.30.41.70.6-0.70.6-0.90.6-0.60.70.70.6-0.6-0.2-0.40.8-0.30.6-0.3-0.9-1.30.3-0.10.5-0.6
Bone: tissue strength0.10.10.3-0.50.4-0.40.4-0.40.4-0.5-0.5-0.50.40.60.5-0.40.30.10.30.20.2-0.20.00.00.0
Total heroin consumption3.84.58.02.3-1.62.1-1.92.1-2.52.42.32.4-2.1-2.2-2.42.8-2.5-0.7-2.4-1.7-1.62.4-2.31.5-1.0
Bone: trabecular number3.66.812.8-3.43.5-3.13.6-3.03.1-3.4-3.4-3.03.13.13.0-3.02.21.31.71.71.5-0.50.00.00.0
Bone: trabecular spacing3.14.58.02.8-2.82.6-2.82.6-2.62.72.62.5-2.7-2.7-2.52.2-2.0-1.7-1.6-0.8-0.50.4-0.00.00.0
Bone: trabecular thickness2.63.76.8-2.52.6-2.12.6-2.22.3-2.5-2.5-2.32.32.32.3-2.21.71.11.31.21.0-0.30.00.00.0
Bone: trabecular tissue density0.10.10.60.2-0.30.5-0.10.4-0.20.10.10.1-0.4-0.3-0.2-0.0-0.3-0.8-0.30.60.70.1-0.10.00.0
Water consumed over 24 hours0.51.12.6-1.21.3-1.51.0-1.41.2-1.0-0.9-1.11.41.10.9-0.81.21.60.9-0.6-0.7-0.50.20.00.0
Number of responses in last shaping day0.20.20.60.4-0.30.6-0.20.7-0.30.30.20.6-0.6-0.6-0.30.1-0.4-0.7-0.60.50.50.3-0.30.4-0.1