Hub : Genes

LOC134481229

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC134481229 0.08 0.03 2.9e-11 0.05 0.07 0.07 0.07 1.5e-08 5.4e-11 1.6e-10 6.3e-11
2 PL alternative TSS XM_063271823.1 0.06 0.04 3.2e-06 0.03 0.05 0.05 0.05 1.9e-04 1.6e-06 4.6e-06 6.1e-06
3 PL alternative TSS XM_063271822.1 0.06 0.04 3.5e-06 0.03 0.05 0.05 0.05 1.4e-04 1.7e-06 3.4e-06 4.3e-06
4 Brain gene expression LOC134481229 0.07 0 2.8e-12 0.09 0.11 0.1 0.11 2.7e-08 2.8e-10 1.2e-09 3.0e-10
5 BLA alternative TSS XM_063271822.1 0.07 0.05 3.2e-04 0.04 0.02 0.02 0.03 2.1e-03 1.8e-02 3.1e-02 1.1e-02
6 BLA alternative TSS XM_063271823.1 0.07 0.05 3.5e-04 0.04 0.02 0.01 0.03 2.0e-03 2.0e-02 1.2e-01 1.3e-02
7 pVTA gene expression LOC134481229 0.11 0.1 2.7e-03 0.01 0.02 0.03 0.01 1.0e-01 1.5e-02 2.0e-03 4.4e-02
8 PL gene expression LOC134481229 0.06 0.02 1.4e-11 0.1 0.11 0.11 0.1 6.3e-11 4.1e-12 1.2e-11 1.9e-11
9 IC gene expression LOC134481229 0.09 0.05 4.9e-05 0.1 0.12 0.13 0.11 7.1e-05 1.2e-05 3.6e-06 3.0e-05
10 Adipose gene expression LOC134481229 0.31 0.01 0.0e+00 0.04 0.15 0.14 0.11 9.0e-05 4.5e-16 2.8e-15 1.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density3.86.510.8-3.23.3-3.3-2.9-2.62.6-2.1-1.9-1.6-0.3
Area under the delay curve0.91.02.80.6-0.40.40.71.5-1.50.21.11.7-0.5
BMI with tail1.03.59.2-2.73.0-3.0-1.9-1.31.3-0.7-0.4-0.21.2
BMI without tail2.37.015.3-3.73.9-3.9-2.9-2.42.4-1.6-1.2-1.10.9
Body weight9.240.175.3-8.58.7-8.7-7.2-6.26.2-4.8-4.1-3.20.4
Weight adjusted by age0.60.92.1-0.80.6-0.7-0.8-1.31.3-0.6-0.9-1.40.1
Bone surface4.07.312.9-3.53.6-3.6-3.0-2.82.8-2.1-1.8-1.60.1
Bone volume1.52.66.0-2.32.4-2.4-1.7-1.51.5-0.9-0.6-0.70.7
Breakpoint value in progressive ratio session0.20.20.7-0.30.3-0.2-0.4-0.20.2-0.8-0.3-0.1-0.8
Number of licking bursts0.00.00.20.0-0.10.1-0.0-0.30.3-0.1-0.2-0.4-0.2
Context. condit. distance diff. score3.23.95.3-2.32.2-2.2-2.2-2.22.2-1.9-1.7-1.6-0.6
Locomotion velocity, session 10.30.30.60.7-0.70.70.50.7-0.70.30.20.5-0.3
Locomotion distance, session 11.41.83.51.8-1.91.91.41.3-1.30.90.70.7-0.3
Locomotion velocity, session 20.40.50.70.8-0.80.80.70.9-0.90.60.40.6-0.1
Locomotion distance, session 21.92.76.72.3-2.62.61.71.3-1.30.70.40.4-0.9
Locomotion velocity, session 30.30.30.6-0.60.5-0.5-0.8-0.40.4-0.7-0.8-0.2-0.7
Locomotion distance, session 30.10.10.4-0.10.1-0.1-0.4-0.20.2-0.4-0.6-0.2-0.7
Stereotopy head waving bouts, day 32.22.63.7-1.91.8-1.8-1.9-1.81.8-1.6-1.5-1.0-0.5
Stereotopy head waving duration, day 30.10.10.10.3-0.30.30.30.2-0.20.30.30.30.2
Locomotion velocity, session 71.21.32.11.0-0.70.71.21.3-1.31.41.41.01.1
Locomotion distance, session 70.40.50.70.8-0.70.70.80.8-0.80.80.70.40.4
Stereotopy head waving bouts, day 70.40.41.80.7-0.90.90.10.2-0.2-0.4-0.6-0.1-1.3
Stereotopy head waving duration, day 70.30.30.80.8-0.90.90.40.4-0.4-0.0-0.20.2-0.8
Locomotion velocity, session 80.10.10.3-0.40.5-0.5-0.4-0.10.1-0.2-0.3-0.2-0.1
Locomotion distance, session 80.50.71.0-1.00.9-0.9-0.9-1.01.0-0.8-0.7-0.9-0.2
Degree of sensitization distance1.21.32.01.1-0.90.91.41.1-1.11.41.40.61.2
Degree of sensitization stereotypy0.40.40.90.8-0.90.90.50.6-0.60.20.00.3-0.6
Conditioned locomotion0.00.00.10.1-0.10.10.10.2-0.20.10.10.3-0.0
Cocaine response after cond. corrected0.70.82.4-0.81.2-1.2-0.10.1-0.10.70.90.61.6
Cocaine response after cond. not corrected0.50.62.0-0.61.0-1.0-0.00.1-0.10.70.90.51.4
Cocaine response before conditioning0.20.20.80.3-0.60.6-0.0-0.30.3-0.5-0.6-0.5-0.9
Saline control response5.26.910.7-2.21.7-1.7-2.8-2.92.9-3.2-3.3-2.5-2.5
Bone: connectivity density7.010.916.4-4.14.0-4.0-3.7-3.63.6-3.0-2.6-2.3-0.6
Bone: cortical apparent density0.70.91.70.7-0.50.51.11.0-1.01.21.30.91.1
Bone: cortical area0.30.40.6-0.80.7-0.7-0.7-0.80.8-0.7-0.6-0.4-0.3
Bone: cortical porosity0.10.10.4-0.20.1-0.1-0.3-0.30.3-0.4-0.5-0.6-0.5
Bone: cortical porosity0.10.20.40.5-0.60.60.20.1-0.1-0.1-0.2-0.4-0.6
Bone: cortical thickness0.60.91.4-1.21.1-1.1-1.1-1.11.1-0.9-0.8-0.5-0.2
Bone: cortical thickness1.41.62.5-1.31.1-1.1-1.3-1.61.6-1.4-1.2-1.2-0.5
Bone: cortical tissue density0.70.91.70.7-0.50.51.11.0-1.01.21.30.91.1
Condit. Reinf. active minus inactive responses0.70.81.10.9-0.70.71.01.0-1.01.01.00.60.6
Condit. Reinf. active-inactive response ratio0.10.10.20.2-0.00.00.30.4-0.40.50.50.20.5
Condit. Reinf. active responses0.60.71.41.1-1.21.20.90.8-0.80.60.40.3-0.3
Condit. Reinf. inactive responses1.11.43.61.7-1.91.91.10.9-0.90.50.20.2-0.8
Incentive salience index mean0.91.12.11.4-1.41.41.21.1-1.10.80.70.5-0.1
Condit. Reinf. lever presses1.62.24.72.0-2.12.21.61.4-1.40.90.60.8-0.6
Condit. Reinf. active minus inactive responses1.52.02.9-1.61.4-1.4-1.5-1.71.7-1.4-1.3-1.2-0.4
Condit. Reinf. active-inactive response ratio0.50.50.8-0.90.9-0.9-0.8-0.80.8-0.6-0.5-0.60.0
Condit. Reinf. active responses1.21.72.3-1.41.2-1.2-1.5-1.51.5-1.5-1.4-1.1-0.7
Condit. Reinf. inactive responses0.40.51.0-0.50.3-0.3-0.7-0.80.8-1.0-1.0-0.6-0.8
Condit. Reinf. lever presses0.00.00.1-0.20.2-0.2-0.10.0-0.00.10.10.20.2
Condit. Reinf. lever reinforcers received0.50.71.0-0.70.5-0.5-0.8-1.01.0-1.0-0.9-0.7-0.6
Conditioned reinforcement - actives2.64.56.9-2.32.1-2.1-2.6-2.02.0-2.4-2.4-1.1-1.5
Conditioned reinforcement - inactives0.30.41.0-0.30.2-0.2-0.7-0.60.6-0.6-1.0-0.8-0.6
Conditioned locomotion3.24.16.7-2.11.8-1.8-2.4-2.12.1-2.6-2.3-1.1-1.7
Patch foraging indifference point 0 sec0.00.00.20.1-0.20.2-0.1-0.00.0-0.3-0.30.1-0.4
Patch foraging indifference point AUC0.81.21.6-1.21.1-1.1-1.2-1.21.2-1.2-1.1-1.0-0.6
Delay disc. indifference point, 0s delay1.31.43.0-1.21.7-1.7-0.20.5-0.50.41.41.11.7
Delay disc. indifference point, 16s delay0.40.41.40.4-0.40.50.20.8-0.8-0.40.11.2-0.9
Delay disc. indifference point, 2s delay1.31.43.60.8-0.60.61.31.4-1.40.81.91.60.7
Delay disc. indifference point, 24s delay0.70.71.40.9-0.80.80.81.2-1.20.30.71.1-0.4
Delay disc. indifference point, 4s delay1.21.32.90.6-0.10.11.01.6-1.60.91.71.50.6
Delay disc. indifference point, 8s delay0.60.71.60.7-0.60.70.31.1-1.1-0.20.31.3-1.3
Indifference point function ln k0.40.72.2-0.2-0.20.2-0.6-0.70.7-1.1-1.2-0.8-1.5
Indifference point function log k0.40.72.2-0.2-0.20.2-0.6-0.70.7-1.1-1.2-0.8-1.5
Patch foraging total patch changes 0 sec0.10.10.30.3-0.50.50.10.0-0.0-0.3-0.4-0.1-0.5
Patch foraging total patch changes 12 sec0.10.10.3-0.50.6-0.6-0.5-0.10.1-0.2-0.30.0-0.0
Patch foraging total patch changes 18 sec0.10.10.30.0-0.10.1-0.3-0.00.0-0.4-0.5-0.6-0.6
Patch foraging total patch changes 24 sec0.30.62.30.3-0.50.5-0.4-0.10.1-0.9-1.1-0.5-1.5
Patch foraging total patch changes 6 sec0.10.20.3-0.30.2-0.2-0.4-0.40.4-0.5-0.6-0.3-0.4
Patch foraging time to switch 0 sec3.06.114.00.70.0-0.12.02.4-2.43.13.52.93.7
Patch foraging water rate 0 sec3.77.813.8-1.81.1-1.1-2.8-3.03.0-3.5-3.7-2.9-3.3
Patch foraging water rate 12 sec0.71.54.2-0.50.1-0.1-1.2-1.01.0-1.5-1.8-1.3-2.1
Patch foraging water rate 18 sec0.40.61.80.8-1.11.10.2-0.00.0-0.4-0.7-0.4-1.3
Patch foraging water rate 24 sec2.63.65.9-1.61.3-1.3-2.2-2.02.0-2.2-2.4-1.7-2.1
Patch foraging water rate 6 sec1.01.42.6-0.70.4-0.4-1.2-1.21.2-1.4-1.6-1.4-1.5
Seeking ratio, delayed vs. immediate footshock1.92.34.41.4-1.31.31.61.6-1.62.11.31.51.5
Distance traveled before self-admin0.20.31.20.3-0.40.40.5-0.20.20.20.6-1.10.6
Distance traveled after self-admin0.30.31.20.3-0.50.5-0.1-0.20.2-0.6-0.7-0.7-1.1
Extensor digitorum longus weight4.116.220.8-4.64.3-4.3-4.5-4.54.5-4.0-3.8-3.5-1.5
Bone: elastic displacement0.50.61.4-0.40.3-0.3-0.8-0.70.7-1.0-1.1-0.7-1.2
Bone: elastic work3.64.76.6-2.42.2-2.1-2.6-2.32.3-2.4-2.3-1.6-1.4
Bone: endosteal estimation0.51.01.4-0.90.8-0.8-1.1-1.11.1-1.2-1.2-0.9-0.9
Bone: endosteal perimeter0.30.62.1-0.1-0.10.1-0.7-0.60.6-1.0-1.2-0.5-1.5
Epididymis fat weight0.00.00.10.10.1-0.10.10.3-0.30.30.20.20.1
Delta time in closed arm before/after self-admin0.40.30.7-0.60.7-0.7-0.7-0.20.2-0.8-0.4-0.3-0.7
Delta time in open arm before/after self-admin2.82.74.82.0-2.22.12.21.2-1.21.71.60.60.9
Diff in mean of infusions in LGA sessions0.20.30.6-0.40.3-0.3-0.6-0.40.4-0.6-0.7-0.5-0.7
Delay discount exponential model param1.21.43.1-0.90.7-0.8-0.9-1.71.7-0.2-1.2-1.80.7
Extinction: sum of active levers before priming0.40.40.70.7-0.70.70.50.9-0.90.10.30.7-0.7
Active lever presses in extinction session 60.20.20.4-0.20.0-0.0-0.3-0.60.6-0.6-0.5-0.5-0.4
Bone: final force1.01.62.6-1.61.6-1.6-1.5-1.31.3-1.1-1.0-0.5-0.2
Bone: final moment0.71.11.8-1.31.3-1.3-1.2-1.11.1-1.0-0.9-0.4-0.2
Food consumed during 24 hour testing period0.00.10.10.3-0.30.30.20.2-0.20.20.0-0.3-0.1
Glucose1.72.73.71.6-1.51.41.91.7-1.71.91.91.21.3
Heart weight1.01.62.8-0.2-0.30.3-0.8-1.61.6-1.7-1.6-1.6-1.5
Delay discount hyperbolic model param1.11.33.2-0.80.6-0.7-0.8-1.61.6-0.3-1.2-1.80.5
Intermittent access intake day 1-15 change0.61.22.2-1.20.9-0.9-1.3-1.41.4-0.7-1.5-0.6-0.4
Intermittent access intake escalation0.40.91.7-1.10.9-0.9-1.2-1.11.1-0.5-1.3-0.4-0.3
Intermittent access intake escalation 20.10.10.30.1-0.20.20.10.0-0.00.5-0.20.60.0
Intermitt. access day 1 inactive lever presses0.00.00.2-0.00.0-0.0-0.3-0.00.00.0-0.4-0.1-0.2
Intermitt. access day 15 inactive lever presses1.02.06.50.20.2-0.21.01.0-1.02.01.81.62.5
Intermitt. access escalation Index0.10.20.70.2-0.40.4-0.00.1-0.1-0.6-0.3-0.3-0.8
Intermittent access day 1 total infusions0.20.31.30.5-0.70.70.10.4-0.4-0.7-0.2-0.2-1.1
Intermittent access day 15 total infusions0.30.41.5-0.30.1-0.1-0.7-0.40.4-1.0-1.0-0.2-1.2
Intermittent access terminal intake (last 3 days)0.10.10.6-0.1-0.10.1-0.3-0.00.0-0.5-0.50.2-0.8
Intermittent access total infusions0.10.10.4-0.0-0.00.0-0.20.2-0.2-0.6-0.10.3-0.6
Intermittent access day 1 locomotion0.30.30.60.6-0.70.70.40.6-0.6-0.60.2-0.1-0.8
Intermittent access day 15 total locomotion0.71.33.0-0.50.2-0.2-1.0-1.01.0-1.7-1.5-1.1-1.7
Intermittent access total locomotion0.20.21.20.2-0.30.3-0.10.1-0.1-0.9-0.3-0.2-1.1
Intermittent access standard deviation0.30.52.7-0.50.5-0.50.0-0.30.31.10.30.71.6
Left kidney weight8.238.259.2-7.77.5-7.5-7.2-6.46.4-5.6-5.2-4.0-1.3
Right kidney weight6.027.645.6-6.76.7-6.8-5.9-5.55.5-4.4-3.8-3.2-0.2
Cocaine induced anxiety0.20.32.40.00.1-0.10.20.6-0.60.10.51.6-0.1
Post-drug Anxiety4.95.313.71.1-0.60.62.12.7-2.72.13.23.71.9
Baseline Anxiety3.94.59.41.3-0.80.82.22.3-2.32.33.12.32.4
Tail length6.525.339.8-6.36.2-6.2-5.7-5.55.5-4.4-3.8-3.2-0.5
Length with tail14.161.295.1-9.89.7-9.6-8.9-8.38.3-6.9-6.2-5.1-1.3
Length without tail8.326.742.3-6.56.4-6.4-5.9-5.45.4-4.6-4.1-3.1-0.8
Times rat made contact with spout0.20.20.4-0.30.3-0.3-0.5-0.40.4-0.5-0.6-0.5-0.5
Lifetime Intake0.10.10.30.3-0.30.30.20.6-0.6-0.10.40.4-0.2
Liver weight, left2.94.86.5-2.42.2-2.2-2.5-2.32.3-2.3-2.3-1.9-1.2
Liver weight, right1.72.94.9-2.22.2-2.2-2.1-1.61.6-1.5-1.4-0.9-0.3
Locomotor activity3.24.99.4-1.30.7-0.7-2.2-2.32.3-2.9-3.1-2.3-2.8
Locomotor testing distance1.83.26.0-1.00.5-0.5-1.7-1.91.9-2.4-2.4-2.0-2.2
Locomotor testing rearing0.51.02.1-0.40.1-0.1-0.9-1.01.0-1.4-1.5-1.2-1.4
Locomotion in novel chamber1.82.23.6-1.51.1-1.1-1.7-1.81.8-1.6-1.9-1.1-1.1
Locomotion in novel chamber post-restriction2.64.27.3-1.51.2-1.2-2.2-2.02.0-2.7-2.6-1.9-2.5
Fecal boli incidents, locomotor time 11.52.13.2-1.51.4-1.4-1.7-1.51.5-1.8-1.5-0.8-1.4
Change in fecal boli incidents, locomotor task0.60.61.50.3-0.10.10.70.5-0.51.21.00.91.2
Time >=10cm from walls, locomotor time 11.92.03.61.2-0.80.91.41.9-1.91.31.81.60.8
Bouts of movement, locomotor time 11.11.32.1-1.21.1-1.1-1.4-0.70.7-1.4-1.4-0.4-1.3
Total resting periods, locomotor time 11.11.21.9-1.11.1-1.1-1.4-0.60.6-1.3-1.3-0.4-1.3
Rest time, locomotor task time 10.70.92.3-1.41.5-1.5-1.2-0.60.6-0.3-0.7-0.10.0
Distance moved, locomotor task time 10.20.40.80.8-0.90.90.60.2-0.2-0.50.20.1-0.8
Vertical activity count, locomotor time 10.40.93.7-0.1-0.30.3-0.6-0.60.6-1.7-1.1-0.4-1.9
Time >=10cm from walls, locomotor time 20.40.71.8-1.01.3-1.3-0.40.0-0.00.20.70.21.1
Bouts of movement, locomotor time 20.81.31.9-1.31.2-1.1-1.4-1.11.1-1.3-1.3-0.3-1.0
Total resting periods, locomotor time 20.61.01.6-1.21.2-1.2-1.3-1.01.0-0.9-1.1-0.2-0.6
Rest time, locomotor task time 20.20.30.70.4-0.30.30.50.6-0.60.80.50.60.4
Distance moved, locomotor task time 20.20.20.4-0.20.1-0.1-0.3-0.50.5-0.6-0.5-0.6-0.4
Vertical activity count, locomotor time 21.82.53.9-1.21.1-1.0-1.7-1.81.8-2.0-1.9-1.5-1.6
Light reinforcement 10.82.03.31.8-1.81.81.71.4-1.41.31.10.40.4
Light reinforcement 20.00.00.10.1-0.00.00.10.2-0.20.30.10.3-0.0
Bone: marrow area0.41.01.4-0.90.8-0.7-1.1-1.11.1-1.1-1.2-0.9-0.9
Bone: maximum diameter0.30.50.6-0.70.7-0.7-0.8-0.80.8-0.8-0.8-0.5-0.4
Bone: maximum force0.71.31.8-1.31.3-1.3-1.3-1.31.3-1.1-1.0-0.8-0.4
Bone: maximum moment0.61.01.3-1.11.0-1.0-1.1-1.11.1-1.0-1.0-0.7-0.4
Mean time between licks in bursts0.41.12.11.4-1.41.41.21.0-1.00.70.60.6-0.2
Mean num. licks in bursts0.10.10.2-0.40.4-0.4-0.4-0.10.1-0.3-0.30.0-0.2
Cd content in liver1.21.45.10.7-1.11.1-0.2-0.50.5-1.1-1.5-1.3-2.3
Co content in liver3.33.85.4-1.81.6-1.6-2.2-2.12.1-2.2-2.3-1.8-1.7
Cu content in liver0.10.10.10.10.00.00.10.4-0.40.40.30.20.3
Fe content in liver0.10.20.60.1-0.20.2-0.2-0.20.2-0.5-0.6-0.3-0.8
K content in liver0.20.20.70.00.0-0.00.40.2-0.20.40.60.70.9
Mg content in liver0.10.10.3-0.50.6-0.6-0.3-0.30.3-0.10.10.20.5
Mn content in liver0.50.50.80.8-0.70.70.80.9-0.90.80.60.40.2
Na content in liver0.20.20.5-0.70.7-0.7-0.4-0.40.4-0.2-0.0-0.00.4
Rb content in liver4.45.26.92.6-2.52.52.62.4-2.42.22.11.90.9
Se content in liver0.60.72.0-1.11.4-1.4-0.7-0.20.2-0.00.10.40.8
Sr content in liver0.10.10.30.1-0.20.2-0.10.0-0.0-0.3-0.3-0.1-0.5
Zn content in liver5.25.88.3-2.82.7-2.7-2.9-2.42.4-2.4-2.3-1.6-1.1
Bone: minimum diameter0.61.12.31.4-1.51.51.10.9-0.90.60.50.6-0.3
Time in familiar zone, hab. session 10.50.50.80.5-0.30.30.70.7-0.70.90.90.60.9
Time in novel zone, hab. session 10.30.30.7-0.60.5-0.5-0.5-0.80.8-0.5-0.3-0.70.2
Total zone transitions, hab. session 12.33.16.62.4-2.62.62.01.6-1.61.31.00.7-0.2
Total locomotion distance, hab. session 11.11.52.51.5-1.61.51.61.0-1.01.21.20.50.7
Locomotion velocity, hab. session 11.82.54.02.0-2.02.01.81.6-1.61.41.31.00.3
Time in familiar zone, hab. session 20.20.20.7-0.40.6-0.6-0.00.2-0.20.40.60.50.9
Time in novel zone, hab. session 20.50.51.51.0-1.21.20.70.4-0.40.1-0.0-0.1-0.6
Total zone transitions, hab. session 20.10.10.40.4-0.60.60.20.0-0.0-0.2-0.3-0.1-0.6
Total locomotion distance, hab. session 20.40.61.41.0-1.21.20.90.5-0.50.40.40.2-0.1
Locomotion velocity, hab. session 20.50.61.51.1-1.21.20.90.6-0.60.50.50.20.0
Novel to familiar place preference ratio0.00.00.00.0-0.10.1-0.0-0.10.1-0.1-0.1-0.2-0.1
Novelty place preference0.10.10.30.5-0.50.50.40.3-0.30.30.30.10.0
Time in novel zone, NPP test0.00.00.10.2-0.20.20.20.1-0.10.10.10.00.0
Total zone transitions, NPP test0.10.20.60.6-0.80.70.50.3-0.30.20.10.1-0.2
Total locomotion distance, NPP test0.40.60.90.9-0.90.90.90.7-0.70.80.80.50.5
Locomotion velocity, NPP test0.30.41.10.9-1.11.00.80.4-0.40.30.30.2-0.1
Intraocular pressure1.21.72.4-1.51.5-1.5-1.5-1.51.5-1.1-1.1-0.7-0.4
Delta distance traveled before/after self-admin0.30.31.80.1-0.30.3-0.40.0-0.0-0.4-1.00.1-1.3
Delta ambulatory time before/after self-admin0.40.51.00.9-1.01.00.40.6-0.60.3-0.30.6-0.9
Parametrial fat weight0.30.82.9-1.01.2-1.3-0.3-0.30.30.30.7-0.01.7
Pavlov. Cond. lever latency3.94.96.8-2.62.5-2.5-2.5-2.52.5-2.2-2.0-1.6-0.8
Pavlov. Cond. magazine entry latency0.10.20.3-0.30.3-0.3-0.5-0.40.4-0.5-0.6-0.3-0.5
Pavlov. Cond. change in total contacts1.61.72.61.2-0.90.91.41.6-1.61.61.51.21.0
Pavlov. Cond. index score0.30.40.60.7-0.60.60.70.8-0.80.60.60.60.1
Pavlov. Cond. latency score0.91.11.51.2-1.11.11.21.2-1.21.11.00.90.3
Pavlov. Cond. lever contacts3.64.35.72.4-2.22.22.42.3-2.32.11.91.50.8
Pavlov. Cond. magazine entry number0.10.20.50.1-0.00.00.40.3-0.30.50.60.30.7
Pavlov. Cond. intertrial magazine entries0.50.61.51.1-1.21.20.80.6-0.60.40.3-0.0-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.6-0.40.40.60.8-0.80.70.70.70.3
Pavlov. Cond. response bias0.00.00.10.2-0.30.30.20.2-0.20.10.10.1-0.1
Pavlov. Cond. lever latency0.40.50.8-0.80.7-0.7-0.8-0.90.9-0.8-0.7-0.6-0.3
Pavlov. Cond. magazine entry latency2.02.43.41.7-1.61.61.71.9-1.91.61.41.40.5
Pavlov. Cond. change in total contacts0.10.10.20.4-0.40.40.40.4-0.40.30.20.3-0.1
Pavlov. Cond. index score1.31.82.51.6-1.51.51.51.6-1.61.31.11.10.2
Pavlov. Cond. latency score1.11.52.11.3-1.21.21.31.4-1.41.21.11.10.4
Pavlov. Cond. lever contacts0.50.81.01.0-0.90.91.01.0-1.00.90.80.60.3
Pavlov. Cond. magazine entry number1.11.31.9-1.41.3-1.3-1.2-1.41.4-1.0-0.9-0.9-0.1
Pavlov. Cond. intertrial magazine entries0.30.51.0-0.2-0.10.1-0.5-0.80.8-0.9-0.9-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.1.41.92.71.6-1.51.61.51.6-1.61.21.11.10.2
Pavlov. Cond. response bias1.01.32.01.4-1.41.41.31.3-1.31.00.90.80.2
Time in closed arm before self-admin2.43.15.0-1.41.0-1.0-1.8-2.12.1-2.2-2.2-1.8-1.4
Time in closed arm after self-admin3.23.46.1-1.61.3-1.2-2.1-1.81.8-2.5-2.3-1.6-2.0
Time in open arm before self-admin0.10.10.4-0.10.2-0.2-0.10.4-0.4-0.20.10.6-0.6
Time in open arm after self-admin1.51.62.71.3-1.31.31.61.0-1.01.61.50.81.0
Bone: periosteal estimation0.51.01.3-1.00.9-0.9-1.1-1.11.1-1.1-1.1-0.8-0.7
Bone: periosteal perimeter0.20.31.40.4-0.60.6-0.1-0.20.2-0.6-0.7-0.2-1.2
Bone: post-yield work0.30.40.9-0.50.3-0.3-0.5-0.80.8-0.7-0.6-1.0-0.3
Progressive ratio test 1 active lever presses1.62.03.0-1.61.4-1.4-1.7-1.41.4-1.7-1.3-1.0-0.9
Progressive ratio test 1 breakpoint1.61.92.9-1.61.4-1.4-1.6-1.31.3-1.7-1.3-1.0-0.8
Progressive ratio test 1 inactive lever presses1.11.62.7-1.10.8-0.8-1.4-1.61.6-1.3-1.6-1.3-0.8
Progressive ratio test 2 active lever presses1.61.93.6-1.20.9-0.9-1.6-1.21.2-1.9-1.8-1.0-1.7
Progressive ratio test 2 breakpoint1.51.73.5-1.10.8-0.8-1.5-1.11.1-1.9-1.7-0.9-1.7
Progressive ratio test 2 inactive lever presses2.43.96.6-1.91.5-1.5-2.3-2.32.3-2.1-2.6-1.6-1.4
Incentive Sensitization - Responses0.10.10.50.3-0.40.4-0.00.1-0.1-0.3-0.4-0.1-0.7
Incentive Sensitization - Breakpoint0.10.20.60.4-0.50.50.10.2-0.2-0.3-0.4-0.0-0.8
Sum of active levers in priming session hrs 5-60.40.41.5-0.20.3-0.30.30.4-0.40.50.81.20.9
Progressive ratio0.61.02.30.5-0.30.31.00.9-0.91.41.40.81.5
Food seeking constrained by brief footshock1.92.45.21.7-1.51.51.61.5-1.52.31.20.91.3
Seeking ratio, punishment vs. effort0.30.51.4-0.30.2-0.2-0.8-0.60.6-0.6-1.2-0.8-0.9
Retroperitoneal fat weight0.31.44.10.20.2-0.20.91.1-1.11.61.71.02.0
Reaction time number correct0.91.62.9-0.80.6-0.5-1.3-1.31.3-1.5-1.7-1.4-1.6
Reaction time mean minus median0.00.10.20.4-0.40.40.10.4-0.4-0.0-0.1-0.0-0.4
Reaction time mean minus median AUC0.10.40.90.8-0.90.90.50.6-0.60.1-0.1-0.1-0.6
Reaction time num false alarms0.20.20.50.5-0.70.70.2-0.20.2-0.3-0.4-0.7-0.6
Reaction time num false alarms AUC0.10.20.50.2-0.40.3-0.1-0.50.5-0.5-0.5-0.7-0.5
Reaction time trials correct on left0.91.62.9-0.80.6-0.5-1.3-1.31.3-1.5-1.7-1.4-1.6
Reaction time trials on left0.81.52.8-0.80.5-0.5-1.3-1.31.3-1.5-1.7-1.3-1.6
Reaction time mean1.52.33.71.7-1.51.51.61.9-1.91.51.41.10.7
Reaction time mean AUC1.21.93.11.6-1.41.41.51.8-1.81.31.20.80.5
Median of all reaction times2.43.45.21.9-1.61.62.02.3-2.32.01.91.31.1
Reaction time omissions0.40.61.20.5-0.30.30.71.1-1.11.10.90.60.8
Reaction time false alarm rate0.10.10.30.5-0.50.50.40.1-0.10.10.2-0.10.1
Reaction time premature initiation rate0.10.10.30.3-0.20.20.50.2-0.20.50.50.20.5
Reaction time premature initiations0.00.10.1-0.10.0-0.1-0.1-0.40.4-0.2-0.2-0.3-0.2
Std. dev. reaction times0.50.91.61.1-0.91.01.01.3-1.30.80.70.80.2
Reaction time trials completed0.81.52.8-0.80.5-0.5-1.3-1.31.3-1.5-1.7-1.3-1.6
Reaction time trials AUC0.71.32.8-0.50.2-0.2-1.1-1.11.1-1.3-1.6-1.3-1.7
Run reversals in cocaine runway, females1.01.01.91.1-1.11.11.21.0-1.01.41.00.20.7
Run reversals in cocaine runway, males0.70.73.00.5-0.80.8-0.2-0.30.3-0.9-1.1-0.2-1.7
Latency to leave start box in cocaine runway0.30.30.9-0.00.3-0.30.40.4-0.40.80.9-0.21.0
Latency to leave start box in cocaine runway, F0.60.62.4-0.61.0-1.0-0.10.0-0.00.90.7-0.31.5
Latency to leave start box in cocaine runway, M0.20.20.50.6-0.70.70.50.3-0.3-0.20.20.0-0.6
Std. dev. time between licks in bursts0.50.71.0-0.60.4-0.4-0.8-0.90.9-1.0-1.0-1.0-0.9
Total sessions with >9 infusions0.20.21.00.10.0-0.00.30.3-0.30.60.60.11.0
Short access day 1 total inactive lever presses0.20.31.3-0.50.6-0.6-0.20.0-0.00.60.20.11.1
Short access day 10 total inactive lever presses0.61.43.0-1.51.5-1.6-0.9-1.11.10.3-0.4-0.31.7
Short access day 1 total infusions0.91.21.81.0-0.90.91.21.2-1.21.31.30.31.3
Short access day 10 total infusions0.30.30.70.6-0.50.50.50.9-0.90.60.40.40.2
Short access total infusions0.81.01.90.7-0.50.51.01.3-1.31.11.40.61.2
Short access day 1 locomotion0.10.10.40.2-0.10.20.10.7-0.7-0.30.30.4-0.5
Short access day 10 total locomotion0.00.00.2-0.00.0-0.1-0.1-0.00.00.4-0.1-0.20.4
Short access total locomotion0.40.40.90.5-0.40.40.61.0-1.00.50.90.60.4
One hour access (0.3 mA shock)2.32.77.8-0.4-0.10.1-1.5-1.31.3-2.0-2.6-1.6-2.8
Compulsive drug intake2.63.14.82.2-2.02.01.92.1-2.11.71.40.90.1
One hour access (shock baseline)2.74.27.2-1.81.4-1.3-2.3-2.12.1-2.7-2.5-1.6-2.2
Social response proportion4.95.68.4-2.92.9-2.9-2.8-2.32.3-2.2-2.0-1.6-0.7
Social responses3.34.36.7-1.91.6-1.6-2.4-2.12.1-2.6-2.5-1.5-2.0
Social time2.12.94.82.2-2.12.21.91.8-1.81.41.21.0-0.1
Soleus weight1.44.15.0-2.22.0-2.0-2.2-2.22.2-2.0-2.0-2.0-0.9
Bone: stiffness0.10.20.2-0.50.5-0.5-0.4-0.50.5-0.4-0.3-0.3-0.1
Tibialis anterior weight4.615.524.1-4.94.9-4.9-4.6-4.04.0-3.5-3.2-2.5-0.8
Time to tail flick, vehicle, before self-admin1.11.12.60.6-0.20.20.91.5-1.50.81.61.30.5
Time to tail flick, vehicle, after self-admin0.10.10.6-0.00.1-0.0-0.20.0-0.0-0.3-0.2-0.8-0.7
Time to tail flick, test, before self-admin1.41.42.0-1.31.2-1.2-1.4-1.31.3-1.0-1.3-1.2-0.5
Time to tail flick, test, after self-admin0.40.41.10.10.1-0.10.50.6-0.60.71.01.01.0
Delta time to tail flick, vehicle, before/after SA0.30.30.90.3-0.50.5-0.1-0.40.4-0.3-0.8-0.9-0.8
Delta time to tail flick, test, before/after SA1.71.82.41.2-1.01.01.51.5-1.51.31.51.51.0
Tibia length3.39.119.5-4.24.4-4.4-3.3-2.82.8-2.0-1.6-1.20.7
Ambulatory time before self-admin0.20.31.8-0.1-0.10.0-0.0-0.70.7-0.3-0.0-1.30.1
Ambulatory time after self-admin0.20.20.60.5-0.80.70.2-0.10.1-0.0-0.4-0.5-0.7
Bone: tissue strength0.20.20.3-0.50.5-0.5-0.5-0.60.6-0.4-0.4-0.6-0.1
Total heroin consumption2.22.64.92.1-2.22.21.61.6-1.60.20.91.3-1.2
Bone: trabecular number4.37.012.4-3.43.5-3.5-3.0-2.72.7-2.1-1.9-1.5-0.1
Bone: trabecular spacing4.45.88.12.9-2.82.82.72.6-2.62.32.11.80.7
Bone: trabecular thickness3.24.06.5-2.62.6-2.6-2.3-2.12.1-1.7-1.5-1.3-0.1
Bone: trabecular tissue density0.10.20.50.2-0.10.10.40.5-0.50.60.70.50.6
Water consumed over 24 hours1.31.72.6-1.31.1-1.1-1.5-1.31.3-1.5-1.6-1.2-1.1
Number of responses in last shaping day0.30.30.60.4-0.20.20.50.7-0.70.70.80.70.6