Hub : Genes

LOC134481148

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC134481148 0.08 0.05 1.6e-03 0.07 0.05 0.04 0.04 1.9e-04 1.9e-03 3.0e-03 3.3e-03
2 PL gene expression LOC134481148 0.14 0.06 1.0e-11 0.09 0.12 0.1 0.11 1.5e-09 1.3e-12 1.9e-11 2.2e-12
3 Adipose gene expression LOC134481148 0.13 0.07 7.8e-05 0.04 0.02 0.03 0.03 2.8e-05 1.7e-03 1.1e-04 1.5e-04
4 Brain gene expression LOC134481148 0.11 0.06 1.7e-03 0.05 0.03 0.03 0.01 3.0e-05 8.9e-04 3.8e-04 1.5e-02
5 NAcc gene expression LOC134481148 0.03 0.02 1.5e-03 0.01 0.01 0.01 0.01 2.9e-03 5.9e-03 2.2e-03 3.2e-03
6 IC gene expression LOC134481148 0.09 0.07 3.8e-03 0.02 0.03 -0 0.01 3.6e-02 1.4e-02 4.3e-01 9.6e-02
7 NAcc intron excision ratio chr12_11033285_11034241 0.01 0.01 3.9e-03 0.01 0.01 0.01 0 1.6e-02 7.0e-03 4.0e-02 6.5e-02
8 NAcc intron excision ratio chr12_11033285_11034497 0.02 0.01 5.4e-05 0.02 0.02 0.01 0.02 1.5e-03 2.0e-04 5.8e-03 1.5e-03
9 PL intron excision ratio chr12_11033285_11034497 0.04 0.03 6.9e-03 0.02 0.02 0.01 0.02 4.1e-03 5.3e-03 3.0e-02 5.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density4.88.916.1-4.03.6-3.2-2.9-3.32.5-2.3-2.52.0
Area under the delay curve0.81.22.21.2-1.11.51.51.2-0.90.80.6-0.9
BMI with tail2.48.410.8-3.02.9-2.6-2.6-3.33.1-3.0-3.12.5
BMI without tail0.10.41.1-0.20.60.30.20.4-1.00.90.5-1.0
Body weight4.017.644.1-6.26.6-4.7-4.6-4.22.3-2.0-2.40.6
Weight adjusted by age0.00.10.5-0.5-0.1-0.3-0.0-0.10.00.10.3-0.7
Bone surface2.34.510.6-3.33.0-2.0-1.9-2.21.6-1.6-1.80.6
Bone volume3.57.012.6-3.53.2-2.3-2.0-2.82.5-2.5-2.81.6
Breakpoint value in progressive ratio session0.40.81.70.30.10.80.50.8-1.21.10.8-1.3
Number of licking bursts0.20.61.3-1.21.0-1.0-1.1-0.8-0.10.30.30.2
Context. condit. distance diff. score0.40.50.9-0.70.90.40.40.10.6-0.8-0.9-0.9
Locomotion velocity, session 10.30.30.70.3-0.40.10.10.5-0.60.70.8-0.8
Locomotion distance, session 10.20.31.00.2-0.7-0.1-0.30.1-0.70.91.0-0.2
Locomotion velocity, session 20.40.51.3-0.70.3-1.1-1.1-0.7-0.30.50.60.2
Locomotion distance, session 21.11.54.30.2-0.4-0.2-0.10.6-1.82.02.1-1.0
Locomotion velocity, session 30.30.30.8-0.50.6-0.2-0.2-0.50.8-0.9-0.9-0.0
Locomotion distance, session 30.40.40.80.5-0.00.20.10.6-0.90.90.8-0.9
Stereotopy head waving bouts, day 30.30.32.0-0.60.20.00.10.3-0.30.30.5-1.4
Stereotopy head waving duration, day 30.40.51.00.4-0.80.90.90.70.3-0.4-0.2-1.0
Locomotion velocity, session 72.42.65.91.7-1.52.42.42.0-0.70.40.2-1.7
Locomotion distance, session 73.14.07.52.1-1.72.72.72.4-1.41.00.8-2.1
Stereotopy head waving bouts, day 72.83.24.81.6-1.31.21.42.0-2.22.22.1-1.7
Stereotopy head waving duration, day 70.60.71.40.8-0.70.30.30.8-1.01.11.2-0.8
Locomotion velocity, session 80.50.61.50.4-0.60.30.20.6-1.01.11.2-0.9
Locomotion distance, session 80.20.41.3-0.70.7-0.2-0.10.2-0.60.60.6-1.1
Degree of sensitization distance1.41.53.61.2-1.41.81.91.4-0.60.40.3-0.9
Degree of sensitization stereotypy0.50.61.00.8-0.60.40.50.8-1.01.01.0-0.4
Conditioned locomotion0.30.31.00.7-1.00.40.30.6-0.40.40.6-0.5
Cocaine response after cond. corrected0.30.52.10.0-0.00.0-0.0-0.60.7-0.8-0.91.4
Cocaine response after cond. not corrected0.40.62.2-0.10.2-0.1-0.0-0.70.8-0.9-1.01.5
Cocaine response before conditioning0.10.10.2-0.00.30.30.40.3-0.20.20.0-0.4
Saline control response2.33.26.21.1-0.80.70.81.8-2.32.42.5-2.3
Bone: connectivity density1.93.07.9-2.82.7-1.9-1.9-1.70.9-0.8-0.9-0.1
Bone: cortical apparent density0.71.11.7-0.60.5-1.3-1.2-1.21.2-1.1-0.91.2
Bone: cortical area0.91.43.5-1.91.9-0.8-0.7-1.10.9-1.0-1.20.2
Bone: cortical porosity0.50.51.20.5-1.10.70.70.7-0.70.70.8-0.4
Bone: cortical porosity1.01.12.10.9-1.51.11.21.1-0.90.80.9-0.8
Bone: cortical thickness1.01.73.1-1.81.7-1.3-1.2-1.31.2-1.2-1.30.7
Bone: cortical thickness1.51.82.81.7-1.21.01.11.6-1.41.41.3-1.3
Bone: cortical tissue density0.71.11.7-0.60.4-1.3-1.2-1.21.2-1.1-0.81.2
Condit. Reinf. active minus inactive responses1.21.42.1-1.31.0-1.1-1.1-1.31.5-1.4-1.20.5
Condit. Reinf. active-inactive response ratio1.31.43.4-0.80.4-0.6-0.6-1.01.8-1.9-1.60.9
Condit. Reinf. active responses0.50.71.1-1.00.7-0.9-0.9-1.00.9-0.8-0.60.5
Condit. Reinf. inactive responses0.10.20.30.2-0.40.30.30.3-0.50.60.5-0.2
Incentive salience index mean0.20.20.3-0.60.6-0.3-0.4-0.50.5-0.5-0.50.3
Condit. Reinf. lever presses0.10.20.50.3-0.50.70.60.2-0.0-0.1-0.20.3
Condit. Reinf. active minus inactive responses1.21.83.21.3-0.90.90.81.5-1.51.51.5-1.8
Condit. Reinf. active-inactive response ratio1.32.13.31.4-1.11.01.11.6-1.61.61.6-1.8
Condit. Reinf. active responses0.91.32.30.8-0.40.40.51.1-1.51.51.5-1.5
Condit. Reinf. inactive responses0.10.10.3-0.20.4-0.3-0.20.1-0.50.60.6-0.1
Condit. Reinf. lever presses0.10.10.20.20.30.40.50.4-0.40.30.1-0.4
Condit. Reinf. lever reinforcers received0.81.12.10.7-0.30.40.41.0-1.41.51.4-1.4
Conditioned reinforcement - actives0.31.43.1-1.61.7-1.8-1.6-1.1-0.00.20.2-0.1
Conditioned reinforcement - inactives0.51.53.1-1.41.6-1.8-1.5-1.30.5-0.4-0.40.8
Conditioned locomotion0.20.20.5-0.60.7-0.5-0.7-0.3-0.30.40.30.2
Patch foraging indifference point 0 sec0.51.52.3-1.51.5-1.4-1.2-1.31.1-1.0-1.00.9
Patch foraging indifference point AUC0.00.10.1-0.20.2-0.2-0.3-0.30.3-0.3-0.30.1
Delay disc. indifference point, 0s delay0.00.00.2-0.00.20.10.10.1-0.0-0.1-0.2-0.4
Delay disc. indifference point, 16s delay0.10.10.50.3-0.30.70.50.20.2-0.3-0.5-0.1
Delay disc. indifference point, 2s delay2.42.74.11.9-1.41.92.01.8-1.61.51.2-1.1
Delay disc. indifference point, 24s delay0.30.41.00.7-0.81.01.00.6-0.1-0.0-0.2-0.6
Delay disc. indifference point, 4s delay0.30.31.10.5-0.70.91.10.4-0.1-0.1-0.2-0.1
Delay disc. indifference point, 8s delay0.40.71.11.1-1.01.01.00.9-0.80.70.7-0.5
Indifference point function ln k0.10.51.1-0.80.8-1.1-1.0-0.5-0.10.30.4-0.0
Indifference point function log k0.10.51.1-0.80.8-1.1-1.0-0.5-0.10.30.4-0.0
Patch foraging total patch changes 0 sec0.31.01.6-1.31.2-1.1-0.9-1.00.9-0.9-0.80.5
Patch foraging total patch changes 12 sec1.62.22.6-1.31.4-1.4-1.4-1.61.6-1.6-1.61.3
Patch foraging total patch changes 18 sec0.30.81.9-0.50.0-0.5-0.5-0.81.4-1.4-1.20.7
Patch foraging total patch changes 24 sec0.00.10.2-0.20.3-0.3-0.3-0.30.4-0.4-0.40.3
Patch foraging total patch changes 6 sec0.00.00.1-0.10.3-0.20.10.1-0.00.0-0.0-0.2
Patch foraging time to switch 0 sec0.10.51.11.0-0.81.01.00.50.2-0.3-0.50.3
Patch foraging water rate 0 sec0.30.92.7-1.71.4-1.2-1.1-0.90.4-0.3-0.2-0.2
Patch foraging water rate 12 sec0.10.40.9-0.80.8-0.5-0.7-0.1-0.30.40.4-1.0
Patch foraging water rate 18 sec0.71.62.41.0-1.21.41.31.5-1.21.11.2-1.5
Patch foraging water rate 24 sec0.50.71.9-0.50.4-0.5-0.60.2-1.01.21.4-1.1
Patch foraging water rate 6 sec0.40.50.9-1.00.8-0.3-0.7-0.50.9-0.9-0.8-0.4
Seeking ratio, delayed vs. immediate footshock0.40.61.71.3-0.40.40.20.7-0.80.90.90.3
Distance traveled before self-admin0.51.02.3-0.4-0.0-0.4-0.6-1.01.5-1.5-1.31.2
Distance traveled after self-admin0.30.51.50.8-1.20.80.80.7-0.0-0.00.1-0.4
Extensor digitorum longus weight0.52.05.2-2.32.2-1.0-0.8-1.31.2-1.2-1.3-0.2
Bone: elastic displacement0.20.20.6-0.1-0.4-0.6-0.6-0.2-0.30.50.80.0
Bone: elastic work0.81.12.4-1.31.3-1.6-1.4-0.7-0.40.70.80.2
Bone: endosteal estimation0.20.61.2-0.81.0-0.4-0.30.1-1.01.11.0-0.8
Bone: endosteal perimeter0.20.62.4-1.41.5-0.4-0.3-0.4-0.10.1-0.1-0.4
Epididymis fat weight1.26.210.3-2.62.5-1.9-1.7-2.43.0-3.1-3.21.4
Delta time in closed arm before/after self-admin0.10.10.6-0.80.4-0.10.1-0.2-0.0-0.0-0.0-0.2
Delta time in open arm before/after self-admin1.51.83.71.9-1.81.61.41.5-1.00.90.8-0.2
Diff in mean of infusions in LGA sessions0.30.61.60.8-0.71.31.20.8-0.2-0.0-0.2-0.5
Delay discount exponential model param1.11.52.7-1.31.3-1.6-1.6-1.30.9-0.8-0.60.9
Extinction: sum of active levers before priming1.01.52.2-1.41.1-1.0-1.1-1.51.2-1.1-1.31.2
Active lever presses in extinction session 60.80.81.3-1.21.1-0.7-1.0-0.80.8-0.9-1.00.3
Bone: final force0.10.10.3-0.50.5-0.4-0.1-0.1-0.40.50.5-0.1
Bone: final moment0.10.10.3-0.60.5-0.5-0.2-0.3-0.20.30.30.2
Food consumed during 24 hour testing period0.61.11.51.1-1.21.01.01.0-1.21.21.20.1
Glucose0.91.42.1-0.71.0-1.3-1.4-1.41.2-1.1-1.01.4
Heart weight0.71.23.2-1.41.8-1.6-1.4-0.9-0.10.30.20.6
Delay discount hyperbolic model param1.31.63.1-1.41.3-1.7-1.8-1.41.0-0.8-0.71.0
Intermittent access intake day 1-15 change0.00.20.9-1.00.3-0.40.3-0.10.1-0.10.0-0.7
Intermittent access intake escalation0.10.31.1-1.10.4-0.7-0.1-0.50.4-0.4-0.2-0.3
Intermittent access intake escalation 20.10.20.5-0.7-0.1-0.40.1-0.40.7-0.7-0.5-0.0
Intermitt. access day 1 inactive lever presses0.11.53.4-1.81.5-1.4-1.3-1.40.8-0.7-0.70.8
Intermitt. access day 15 inactive lever presses0.00.20.40.6-0.30.40.60.20.3-0.4-0.60.6
Intermitt. access escalation Index0.00.00.10.3-0.30.30.10.1-0.0-0.0-0.00.2
Intermittent access day 1 total infusions0.51.53.21.0-0.70.50.31.2-1.71.81.7-1.1
Intermittent access day 15 total infusions0.20.61.3-0.10.1-0.30.10.5-1.01.11.1-1.0
Intermittent access terminal intake (last 3 days)0.10.20.60.1-0.3-0.20.20.3-0.70.80.8-0.6
Intermittent access total infusions0.40.41.20.2-0.1-0.10.10.4-1.11.11.0-0.4
Intermittent access day 1 locomotion0.20.40.90.6-0.30.1-0.10.5-0.90.90.90.0
Intermittent access day 15 total locomotion0.72.54.21.3-1.21.21.31.7-2.12.12.0-1.2
Intermittent access total locomotion0.81.02.50.8-0.70.40.40.8-1.51.61.50.0
Intermittent access standard deviation0.20.92.1-1.41.0-1.0-0.4-1.00.9-0.9-0.90.3
Left kidney weight1.612.635.6-5.36.0-4.0-3.7-3.31.7-1.5-1.80.7
Right kidney weight2.517.142.7-6.06.5-4.7-4.4-4.22.3-2.0-2.41.2
Cocaine induced anxiety0.30.71.41.1-1.01.21.00.9-0.60.50.4-0.6
Post-drug Anxiety0.91.02.51.5-1.11.61.41.0-0.60.30.1-0.1
Baseline Anxiety0.20.31.0-0.10.6-0.1-0.2-0.40.3-0.4-0.81.0
Tail length1.05.511.9-1.52.3-0.6-0.51.1-3.13.22.9-3.4
Length with tail1.98.327.7-4.65.3-2.9-2.6-1.3-0.91.20.8-2.5
Length without tail3.116.035.4-5.96.0-4.4-4.1-4.12.7-2.4-2.51.1
Times rat made contact with spout0.40.51.40.2-0.50.20.30.5-0.91.01.2-0.4
Lifetime Intake0.20.30.90.2-0.0-0.3-0.10.2-0.91.00.8-0.1
Liver weight, left0.81.45.1-2.02.3-1.1-1.1-0.80.3-0.3-0.4-0.8
Liver weight, right1.01.75.6-2.32.4-1.2-1.2-1.1-0.10.2-0.1-0.1
Locomotor activity0.20.41.5-1.20.9-0.3-0.0-0.30.0-0.0-0.1-0.9
Locomotor testing distance0.41.02.1-1.41.0-1.0-0.8-1.21.1-1.0-0.90.3
Locomotor testing rearing0.00.10.4-0.0-0.50.50.60.20.2-0.4-0.3-0.4
Locomotion in novel chamber3.14.210.21.1-1.10.60.81.7-2.93.13.2-1.6
Locomotion in novel chamber post-restriction0.51.44.0-0.60.3-0.3-0.30.3-1.82.01.8-0.8
Fecal boli incidents, locomotor time 10.30.92.1-1.11.4-1.1-1.1-0.90.7-0.6-0.5-0.4
Change in fecal boli incidents, locomotor task0.20.20.40.3-0.40.20.70.1-0.40.40.30.5
Time >=10cm from walls, locomotor time 10.30.30.7-0.20.7-0.7-0.8-0.4-0.40.50.40.8
Bouts of movement, locomotor time 10.00.00.1-0.2-0.1-0.0-0.10.00.3-0.3-0.2-0.3
Total resting periods, locomotor time 10.10.10.2-0.2-0.0-0.1-0.1-0.20.4-0.4-0.40.0
Rest time, locomotor task time 10.10.20.50.2-0.60.10.30.3-0.50.60.70.1
Distance moved, locomotor task time 10.00.10.30.10.1-0.0-0.4-0.10.4-0.5-0.50.1
Vertical activity count, locomotor time 10.21.11.3-1.11.1-0.8-1.1-1.11.1-1.1-1.10.6
Time >=10cm from walls, locomotor time 20.00.10.3-0.20.5-0.1-0.20.0-0.30.30.2-0.4
Bouts of movement, locomotor time 20.41.22.8-1.51.7-1.3-1.3-1.10.5-0.5-0.6-0.2
Total resting periods, locomotor time 20.51.93.7-1.81.9-1.6-1.6-1.50.9-0.8-0.90.4
Rest time, locomotor task time 20.10.20.30.4-0.30.20.40.4-0.50.50.50.5
Distance moved, locomotor task time 20.10.20.2-0.50.1-0.3-0.5-0.30.5-0.4-0.4-0.4
Vertical activity count, locomotor time 21.02.33.7-1.91.5-1.6-1.9-1.61.5-1.4-1.30.6
Light reinforcement 10.10.31.30.6-1.10.50.3-0.00.2-0.3-0.20.8
Light reinforcement 20.81.83.2-1.00.1-0.9-1.1-1.51.8-1.7-1.41.7
Bone: marrow area0.20.61.3-0.70.9-0.4-0.30.1-1.01.11.0-0.8
Bone: maximum diameter0.71.44.4-2.12.0-0.9-0.9-1.10.6-0.6-0.8-0.1
Bone: maximum force0.10.20.5-0.60.7-0.3-0.0-0.0-0.40.50.3-0.2
Bone: maximum moment0.10.20.5-0.70.7-0.4-0.2-0.2-0.30.30.20.1
Mean time between licks in bursts0.00.20.50.5-0.60.40.50.6-0.30.30.4-0.7
Mean num. licks in bursts0.41.02.21.3-1.51.11.21.1-0.50.40.6-0.6
Cd content in liver0.10.20.6-0.1-0.2-0.1-0.00.1-0.50.60.8-0.2
Co content in liver0.50.62.10.9-1.50.50.50.6-0.60.70.8-0.3
Cu content in liver1.31.53.1-1.30.8-0.4-0.6-1.11.7-1.8-1.70.5
Fe content in liver5.06.19.7-2.92.4-1.6-1.6-2.43.1-3.1-3.11.1
K content in liver0.10.00.10.0-0.20.40.10.1-0.30.30.1-0.2
Mg content in liver1.01.12.11.1-1.21.41.21.3-0.70.60.6-1.1
Mn content in liver0.10.10.40.0-0.30.2-0.10.3-0.40.50.6-0.5
Na content in liver0.30.30.8-0.30.8-0.7-0.9-0.5-0.50.50.30.3
Rb content in liver2.42.85.92.1-2.22.42.41.70.1-0.5-0.5-0.8
Se content in liver3.03.56.3-1.71.3-1.0-1.1-2.12.2-2.3-2.51.9
Sr content in liver0.60.51.8-1.31.0-0.7-0.7-0.6-0.10.20.1-0.5
Zn content in liver1.92.25.1-2.32.0-1.7-1.7-1.71.0-0.8-0.80.5
Bone: minimum diameter0.10.30.9-0.0-0.10.81.00.5-0.30.2-0.0-0.6
Time in familiar zone, hab. session 10.80.91.4-1.10.7-0.9-0.9-1.20.8-0.7-0.61.1
Time in novel zone, hab. session 10.20.21.00.10.20.30.40.5-0.20.1-0.0-1.0
Total zone transitions, hab. session 14.46.211.71.5-1.11.71.72.5-3.43.43.2-2.5
Total locomotion distance, hab. session 12.63.75.31.7-1.42.02.12.3-2.12.01.8-1.8
Locomotion velocity, hab. session 13.14.46.12.2-1.92.22.32.5-2.22.01.8-1.6
Time in familiar zone, hab. session 20.60.72.0-0.30.10.60.7-0.11.2-1.4-1.4-0.2
Time in novel zone, hab. session 20.30.30.70.4-0.2-0.5-0.50.0-0.70.80.80.2
Total zone transitions, hab. session 21.01.34.00.1-0.4-0.3-0.30.4-1.72.02.0-0.7
Total locomotion distance, hab. session 21.01.33.10.9-1.00.40.40.8-1.61.71.8-0.5
Locomotion velocity, hab. session 21.01.33.40.8-0.90.20.20.7-1.61.81.9-0.4
Novel to familiar place preference ratio0.10.20.7-0.10.3-0.6-0.8-0.50.00.10.10.3
Novelty place preference0.20.20.8-0.20.4-0.8-0.9-0.60.2-0.1-0.00.5
Time in novel zone, NPP test0.30.31.1-0.40.5-0.9-1.0-0.70.3-0.1-0.00.5
Total zone transitions, NPP test0.71.02.6-0.1-0.0-0.1-0.00.5-1.41.61.6-1.2
Total locomotion distance, NPP test1.41.93.01.1-1.01.31.41.4-1.71.71.5-1.0
Locomotion velocity, NPP test2.13.04.61.4-1.31.51.61.8-2.12.12.0-1.5
Intraocular pressure0.10.20.4-0.30.60.00.30.00.4-0.5-0.5-0.4
Delta distance traveled before/after self-admin2.62.93.71.5-1.51.41.81.8-1.71.71.7-1.9
Delta ambulatory time before/after self-admin1.22.02.91.5-1.61.41.71.6-1.21.11.1-1.4
Parametrial fat weight0.82.04.6-1.62.2-1.5-1.8-1.50.9-0.9-1.00.8
Pavlov. Cond. lever latency3.95.07.7-2.62.6-2.7-2.8-2.51.8-1.6-1.41.5
Pavlov. Cond. magazine entry latency3.64.76.91.7-1.32.02.02.3-2.62.52.3-2.3
Pavlov. Cond. change in total contacts1.92.04.01.4-1.32.02.01.6-1.00.80.6-1.2
Pavlov. Cond. index score3.84.86.12.1-1.92.42.42.5-2.32.11.8-2.1
Pavlov. Cond. latency score4.05.06.22.3-2.12.42.42.5-2.42.22.0-2.0
Pavlov. Cond. lever contacts5.36.410.12.9-2.83.13.22.9-2.11.81.6-1.8
Pavlov. Cond. magazine entry number4.55.77.5-2.01.5-2.5-2.4-2.72.7-2.5-2.22.7
Pavlov. Cond. intertrial magazine entries0.70.91.4-0.70.4-1.2-1.1-1.11.0-0.9-0.71.2
Pavlov. Cond. lever-magazine prob. diff.3.24.05.52.0-1.72.32.32.3-2.01.81.5-1.8
Pavlov. Cond. response bias4.45.57.22.2-1.82.72.62.7-2.42.21.9-2.5
Pavlov. Cond. lever latency0.50.71.4-0.90.8-1.0-1.2-1.00.6-0.5-0.40.7
Pavlov. Cond. magazine entry latency0.00.00.2-0.10.20.30.40.1-0.10.0-0.0-0.4
Pavlov. Cond. change in total contacts0.10.30.90.20.00.40.70.7-0.60.50.4-0.9
Pavlov. Cond. index score0.30.50.70.5-0.30.60.80.8-0.80.70.6-0.8
Pavlov. Cond. latency score0.20.40.60.5-0.30.60.80.7-0.70.70.6-0.8
Pavlov. Cond. lever contacts0.40.61.60.9-0.81.11.30.9-0.50.30.2-0.5
Pavlov. Cond. magazine entry number0.00.00.1-0.0-0.1-0.2-0.3-0.20.2-0.2-0.10.3
Pavlov. Cond. intertrial magazine entries0.30.61.30.7-0.50.30.20.7-1.11.21.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.4-0.20.60.80.7-0.80.70.6-0.9
Pavlov. Cond. response bias0.60.92.11.1-0.81.31.51.1-0.70.50.3-0.7
Time in closed arm before self-admin0.61.03.2-0.91.1-1.6-1.8-0.90.5-0.3-0.0-0.1
Time in closed arm after self-admin0.70.81.9-1.11.2-1.4-1.1-0.7-0.10.30.5-0.8
Time in open arm before self-admin0.10.10.1-0.10.30.10.20.2-0.30.30.3-0.3
Time in open arm after self-admin1.31.42.71.6-1.61.61.51.3-0.80.60.4-0.2
Bone: periosteal estimation0.20.52.1-1.41.5-0.5-0.4-0.4-0.20.20.0-0.4
Bone: periosteal perimeter0.40.82.6-1.51.6-0.4-0.2-0.60.5-0.6-0.8-0.0
Bone: post-yield work0.30.40.9-0.60.2-0.3-0.0-0.70.9-0.9-0.90.7
Progressive ratio test 1 active lever presses0.30.51.2-0.00.4-0.3-0.30.4-1.01.11.0-0.8
Progressive ratio test 1 breakpoint0.30.51.2-0.00.4-0.3-0.30.4-1.11.11.0-0.8
Progressive ratio test 1 inactive lever presses0.10.20.6-0.60.8-0.7-0.6-0.2-0.30.40.3-0.1
Progressive ratio test 2 active lever presses1.11.52.4-1.21.5-1.5-1.4-0.5-1.11.41.3-0.0
Progressive ratio test 2 breakpoint1.11.42.3-1.21.5-1.5-1.4-0.6-1.11.41.2-0.0
Progressive ratio test 2 inactive lever presses0.30.92.3-0.91.5-1.0-0.5-0.2-1.11.20.9-0.5
Incentive Sensitization - Responses0.61.73.4-1.51.9-1.7-1.6-1.1-0.60.90.70.7
Incentive Sensitization - Breakpoint0.71.63.1-1.51.8-1.7-1.6-1.1-0.70.90.80.8
Sum of active levers in priming session hrs 5-60.40.41.3-0.91.2-0.7-0.7-0.5-0.10.10.0-0.1
Progressive ratio0.20.61.50.6-0.00.30.20.6-1.21.21.1-0.1
Food seeking constrained by brief footshock1.31.72.7-1.20.6-1.5-1.5-1.61.5-1.3-0.91.1
Seeking ratio, punishment vs. effort0.51.11.8-1.20.5-1.2-1.1-1.21.3-1.1-0.80.4
Retroperitoneal fat weight1.46.410.8-2.93.3-1.9-2.1-2.62.6-2.6-3.01.1
Reaction time number correct0.30.92.0-1.41.3-1.2-1.3-0.9-0.10.30.40.3
Reaction time mean minus median1.811.416.23.4-2.73.93.84.0-3.32.92.6-3.5
Reaction time mean minus median AUC1.711.616.53.6-2.73.83.64.1-3.43.02.8-3.3
Reaction time num false alarms0.10.10.3-0.20.1-0.5-0.3-0.3-0.20.30.40.6
Reaction time num false alarms AUC0.10.10.4-0.40.3-0.4-0.2-0.40.2-0.1-0.10.7
Reaction time trials correct on left0.30.92.0-1.41.3-1.2-1.3-0.9-0.10.30.40.3
Reaction time trials on left0.20.81.8-1.31.2-1.1-1.2-0.8-0.20.40.40.2
Reaction time mean2.24.99.13.0-2.93.03.02.4-1.10.80.7-1.0
Reaction time mean AUC2.04.99.22.9-2.83.03.02.4-1.00.70.7-1.2
Median of all reaction times1.52.45.72.3-2.42.12.11.30.0-0.3-0.30.1
Reaction time omissions1.52.54.21.8-1.82.01.91.9-1.21.01.0-1.2
Reaction time false alarm rate0.10.10.20.1-0.1-0.00.2-0.10.4-0.4-0.40.5
Reaction time premature initiation rate6.39.713.13.6-3.22.92.93.3-3.43.33.3-1.9
Reaction time premature initiations2.47.210.82.7-2.42.12.12.7-3.33.33.3-1.8
Std. dev. reaction times2.89.414.23.4-2.73.83.83.6-2.72.32.0-2.7
Reaction time trials completed0.20.81.8-1.31.2-1.1-1.2-0.8-0.20.40.40.2
Reaction time trials AUC0.30.92.0-1.41.3-1.2-1.3-1.00.00.20.20.4
Run reversals in cocaine runway, females0.20.20.90.7-0.90.50.20.20.0-0.10.00.0
Run reversals in cocaine runway, males0.80.91.5-1.20.7-1.0-0.9-1.01.1-1.0-0.80.3
Latency to leave start box in cocaine runway0.30.41.4-0.00.20.40.2-0.10.9-1.1-1.20.1
Latency to leave start box in cocaine runway, F0.91.23.0-0.81.0-0.3-0.4-0.71.5-1.6-1.70.2
Latency to leave start box in cocaine runway, M0.40.40.60.7-0.70.60.40.7-0.60.60.7-0.5
Std. dev. time between licks in bursts0.10.10.30.00.3-0.3-0.2-0.0-0.50.50.50.1
Total sessions with >9 infusions1.01.22.9-1.21.1-1.7-1.6-1.30.7-0.6-0.40.6
Short access day 1 total inactive lever presses0.40.82.9-1.31.7-1.1-1.0-0.5-0.30.40.2-0.4
Short access day 10 total inactive lever presses0.00.20.6-0.70.8-0.10.1-0.40.3-0.4-0.60.4
Short access day 1 total infusions0.40.82.0-0.80.9-1.4-1.4-1.00.5-0.4-0.30.5
Short access day 10 total infusions0.10.20.4-0.00.1-0.5-0.3-0.0-0.60.60.6-0.1
Short access total infusions0.20.20.7-0.10.4-0.8-0.8-0.4-0.20.30.30.5
Short access day 1 locomotion0.30.61.5-0.80.6-1.2-1.1-0.90.5-0.3-0.20.4
Short access day 10 total locomotion0.20.81.3-1.11.2-1.1-1.1-1.00.6-0.5-0.50.4
Short access total locomotion0.10.10.3-0.20.2-0.5-0.5-0.3-0.10.10.20.2
One hour access (0.3 mA shock)0.91.12.80.4-0.30.10.30.9-1.51.71.6-1.0
Compulsive drug intake1.11.64.21.7-2.01.61.41.4-0.50.50.6-0.4
One hour access (shock baseline)0.20.41.1-0.40.7-0.5-0.00.1-1.01.00.8-0.5
Social response proportion1.11.44.60.4-0.30.81.01.3-1.31.21.2-2.1
Social responses4.86.310.92.1-1.62.42.42.9-2.72.52.3-3.3
Social time0.81.32.91.4-1.21.61.71.3-0.3-0.0-0.2-0.8
Soleus weight0.20.72.0-1.41.4-0.2-0.3-0.50.7-0.8-0.9-0.5
Bone: stiffness0.20.40.90.30.20.30.60.6-1.00.90.7-0.3
Tibialis anterior weight0.51.64.8-2.22.2-1.3-1.2-1.00.3-0.2-0.2-0.8
Time to tail flick, vehicle, before self-admin0.10.20.5-0.1-0.20.40.10.00.6-0.6-0.7-0.0
Time to tail flick, vehicle, after self-admin0.10.20.7-0.20.9-0.5-0.3-0.30.2-0.2-0.30.2
Time to tail flick, test, before self-admin0.91.12.9-1.51.7-1.4-1.3-0.9-0.10.20.10.0
Time to tail flick, test, after self-admin0.30.30.50.6-0.50.50.60.10.4-0.4-0.50.7
Delta time to tail flick, vehicle, before/after SA0.70.71.6-0.40.9-0.9-0.4-1.00.8-0.8-0.81.3
Delta time to tail flick, test, before/after SA0.81.02.61.3-1.61.31.30.8-0.1-0.00.10.4
Tibia length0.71.97.2-2.12.7-1.7-1.3-0.9-0.20.30.0-0.4
Ambulatory time before self-admin0.20.71.5-0.3-0.1-0.4-0.5-0.71.2-1.2-1.01.0
Ambulatory time after self-admin0.30.51.60.9-1.30.80.80.60.2-0.2-0.1-0.5
Bone: tissue strength2.42.53.8-1.91.5-1.7-1.9-1.91.2-1.0-0.81.8
Total heroin consumption0.60.71.90.9-1.01.41.10.9-0.60.40.2-0.4
Bone: trabecular number1.93.68.0-2.82.6-1.9-1.8-2.01.5-1.4-1.50.5
Bone: trabecular spacing0.20.31.01.0-0.60.60.70.4-0.1-0.0-0.10.5
Bone: trabecular thickness4.46.29.6-3.12.9-2.6-2.6-2.82.0-1.9-2.02.1
Bone: trabecular tissue density0.10.10.7-0.10.9-0.2-0.0-0.1-0.0-0.1-0.30.5
Water consumed over 24 hours0.30.61.8-0.40.2-0.2-0.20.1-1.21.31.3-0.3
Number of responses in last shaping day0.50.61.0-0.90.4-0.7-0.6-0.91.0-1.0-0.90.4