Hub : Genes

LOC134481147

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	LOC134481147	0.05	0.06	6.1e-03	0.02	0.01	0.02	0.01	6.0e-03	8.2e-03	6.0e-03	8.3e-03
2	pVTA	gene expression	LOC134481147	0.05	0.03	3.6e-03	0.03	0.02	0.03	0.03	1.3e-03	5.6e-03	2.9e-03	1.9e-03
3	Brain	gene expression	LOC134481147	0.09	0.05	3.3e-07	0.06	0.09	0.08	0.08	1.7e-06	1.4e-08	4.3e-08	7.1e-08
4	IL	gene expression	LOC134481147	0.14	0.1	3.7e-03	0.13	0.11	0.1	0.1	5.1e-04	1.4e-03	2.3e-03	2.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	6.8	12.5	19.3	-4.2	-4.4	3.2	-1.7
Area under the delay curve	0.7	1.0	2.0	1.4	0.7	-1.2	0.4
BMI with tail	3.3	11.6	17.6	-4.2	-3.8	3.2	-1.9
BMI without tail	0.7	3.7	11.7	-3.4	-1.2	0.4	1.2
Body weight	9.1	39.6	76.4	-8.7	-7.1	5.4	-1.8
Weight adjusted by age	0.3	0.8	1.3	-1.0	-1.1	-0.1	0.9
Bone surface	5.6	10.9	17.7	-4.1	-4.2	2.8	-1.2
Bone volume	6.1	12.1	18.6	-3.8	-4.3	3.3	-2.1
Breakpoint value in progressive ratio session	0.1	0.2	0.4	-0.2	0.5	-0.4	0.6
Number of licking bursts	0.2	0.6	0.9	0.7	-0.9	0.5	0.9
Context. condit. distance diff. score	2.9	3.5	8.8	-3.0	-1.4	1.4	-1.1
Locomotion velocity, session 1	1.3	1.4	2.5	0.6	1.6	-1.5	0.7
Locomotion distance, session 1	1.6	2.0	4.2	1.1	1.0	-2.0	1.3
Locomotion velocity, session 2	1.2	1.4	1.9	1.2	0.9	-1.3	1.4
Locomotion distance, session 2	2.3	3.2	4.5	1.9	1.0	-2.1	2.0
Locomotion velocity, session 3	0.5	0.6	0.7	-0.7	-0.8	0.9	-0.7
Locomotion distance, session 3	0.2	0.2	0.5	-0.3	-0.1	-0.5	0.7
Stereotopy head waving bouts, day 3	0.9	1.1	2.0	-1.4	-0.3	-0.7	1.3
Stereotopy head waving duration, day 3	0.0	0.1	0.2	0.0	0.0	-0.5	0.2
Locomotion velocity, session 7	0.3	0.3	1.0	1.0	0.1	-0.3	-0.4
Locomotion distance, session 7	0.1	0.2	0.3	0.5	0.3	-0.4	-0.4
Stereotopy head waving bouts, day 7	2.7	3.1	4.1	1.5	1.6	-2.0	1.9
Stereotopy head waving duration, day 7	1.9	2.4	3.7	1.9	1.5	-1.4	1.3
Locomotion velocity, session 8	0.8	1.0	1.7	0.1	1.0	-1.3	1.1
Locomotion distance, session 8	0.5	0.7	2.3	-1.5	-0.7	-0.1	0.4
Degree of sensitization distance	0.9	0.9	2.3	1.5	1.0	-0.6	-0.1
Degree of sensitization stereotypy	1.5	1.7	2.4	1.5	1.4	-1.3	0.9
Conditioned locomotion	0.6	0.7	2.2	-1.5	-0.4	-0.5	0.4
Cocaine response after cond. corrected	0.2	0.3	1.0	-0.2	0.5	0.1	-1.0
Cocaine response after cond. not corrected	0.4	0.6	1.5	-0.6	0.6	0.1	-1.2
Cocaine response before conditioning	0.3	0.3	0.7	-0.8	-0.2	0.3	-0.6
Saline control response	1.3	1.8	4.5	-1.1	-0.2	-1.1	2.1
Bone: connectivity density	6.6	10.6	19.2	-4.4	-4.1	2.4	-0.7
Bone: cortical apparent density	0.3	0.4	1.0	0.6	-0.2	0.7	-1.0
Bone: cortical area	2.2	3.6	6.5	-2.0	-2.5	1.8	-0.9
Bone: cortical porosity	1.5	1.7	2.3	0.7	1.3	-1.5	1.5
Bone: cortical porosity	1.7	1.8	2.4	1.0	1.4	-1.5	1.4
Bone: cortical thickness	2.0	3.4	5.7	-2.1	-2.4	1.7	-0.8
Bone: cortical thickness	0.4	0.4	0.9	-0.8	-0.4	-0.0	1.0
Bone: cortical tissue density	0.2	0.4	0.8	0.6	-0.0	0.6	-0.9
Condit. Reinf. active minus inactive responses	1.0	1.1	2.4	-0.3	-1.5	1.1	-0.8
Condit. Reinf. active-inactive response ratio	1.4	1.5	2.8	-0.2	-1.7	1.4	-1.1
Condit. Reinf. active responses	0.1	0.1	0.2	-0.3	-0.5	0.3	-0.1
Condit. Reinf. inactive responses	0.8	1.0	2.2	0.6	1.5	-1.1	0.7
Incentive salience index mean	0.4	0.5	1.1	-0.6	-1.0	0.4	-0.4
Condit. Reinf. lever presses	0.1	0.2	0.4	-0.6	0.1	-0.5	-0.0
Condit. Reinf. active minus inactive responses	0.5	0.8	1.8	0.3	0.7	-0.8	1.4
Condit. Reinf. active-inactive response ratio	1.3	2.0	3.8	1.0	1.1	-1.4	2.0
Condit. Reinf. active responses	0.2	0.4	1.0	-0.5	-0.0	-0.4	1.0
Condit. Reinf. inactive responses	0.5	0.7	1.8	-1.3	-0.9	0.4	-0.4
Condit. Reinf. lever presses	0.6	0.9	1.8	-1.4	-1.1	0.6	-0.3
Condit. Reinf. lever reinforcers received	0.2	0.3	0.8	-0.2	-0.2	-0.4	0.9
Conditioned reinforcement - actives	0.2	0.9	3.2	-1.8	0.4	0.2	0.5
Conditioned reinforcement - inactives	0.0	0.1	0.3	0.2	0.6	0.2	-0.2
Conditioned locomotion	0.3	0.4	1.1	-1.0	0.6	0.1	-0.0
Patch foraging indifference point 0 sec	1.5	4.2	7.6	-2.0	-2.8	1.8	-1.4
Patch foraging indifference point AUC	0.4	0.9	2.0	-1.4	-1.2	0.4	-0.1
Delay disc. indifference point, 0s delay	0.1	0.2	0.3	0.5	-0.4	0.2	-0.4
Delay disc. indifference point, 16s delay	0.1	0.1	0.3	0.6	0.1	-0.4	-0.3
Delay disc. indifference point, 2s delay	1.3	1.4	3.0	1.7	1.1	-1.2	0.0
Delay disc. indifference point, 24s delay	0.7	1.1	3.2	1.8	0.8	-0.8	0.2
Delay disc. indifference point, 4s delay	0.6	0.6	1.4	0.7	0.6	-1.2	0.3
Delay disc. indifference point, 8s delay	0.1	0.3	0.6	0.8	0.1	-0.6	0.2
Indifference point function ln k	0.0	0.1	0.2	0.3	0.0	0.4	0.2
Indifference point function log k	0.0	0.1	0.2	0.3	0.0	0.4	0.2
Patch foraging total patch changes 0 sec	1.5	4.3	7.4	-2.2	-2.7	1.7	-1.4
Patch foraging total patch changes 12 sec	4.4	5.9	9.0	-2.8	-3.0	1.9	-1.8
Patch foraging total patch changes 18 sec	0.9	2.0	3.3	-1.7	-1.8	1.0	-1.0
Patch foraging total patch changes 24 sec	0.6	1.9	3.5	-1.9	-1.8	0.8	-0.7
Patch foraging total patch changes 6 sec	1.4	2.3	4.8	-2.2	-1.8	0.9	-0.7
Patch foraging time to switch 0 sec	0.3	1.3	2.2	1.5	1.5	-0.8	-0.5
Patch foraging water rate 0 sec	0.9	3.2	6.1	-2.5	-2.0	1.6	-0.1
Patch foraging water rate 12 sec	0.1	0.4	0.7	0.0	-0.7	0.6	0.9
Patch foraging water rate 18 sec	0.5	1.2	2.5	0.6	0.9	-0.9	1.6
Patch foraging water rate 24 sec	1.0	1.4	3.8	-1.1	-0.7	-0.3	2.0
Patch foraging water rate 6 sec	0.9	1.3	2.1	-1.0	-1.3	1.5	-0.5
Seeking ratio, delayed vs. immediate footshock	0.7	0.9	2.1	1.2	1.4	-0.5	0.1
Distance traveled before self-admin	0.1	0.3	0.5	0.7	0.1	0.4	-0.7
Distance traveled after self-admin	0.0	0.0	0.1	-0.2	-0.4	-0.0	-0.1
Extensor digitorum longus weight	2.6	10.5	21.8	-4.7	-3.1	2.8	-1.5
Bone: elastic displacement	1.1	1.4	2.6	0.4	1.0	-1.4	1.6
Bone: elastic work	1.6	2.1	4.3	-2.1	-1.6	0.5	1.1
Bone: endosteal estimation	0.3	0.7	1.2	-0.8	-1.1	0.3	0.8
Bone: endosteal perimeter	0.8	2.0	3.7	-1.8	-1.9	1.1	-0.2
Epididymis fat weight	1.3	6.5	9.0	-1.8	-2.2	2.9	-3.0
Delta time in closed arm before/after self-admin	0.2	0.2	0.4	-0.0	-0.5	0.7	-0.2
Delta time in open arm before/after self-admin	2.0	2.4	3.3	1.7	1.8	-1.8	0.5
Diff in mean of infusions in LGA sessions	0.0	0.1	0.2	-0.3	0.1	0.4	0.2
Delay discount exponential model param	1.0	1.4	2.8	-1.7	-1.0	1.3	-0.4
Extinction: sum of active levers before priming	0.7	1.1	1.6	-0.7	-1.3	1.0	-1.1
Active lever presses in extinction session 6	2.0	2.0	3.3	-1.2	-1.8	1.5	-1.0
Bone: final force	0.8	1.3	2.4	-1.6	-1.3	0.6	0.8
Bone: final moment	0.7	1.1	1.9	-1.4	-1.2	0.5	0.8
Food consumed during 24 hour testing period	0.8	1.5	2.4	0.1	1.5	-1.5	1.2
Glucose	0.7	1.1	2.3	1.5	0.9	0.5	-1.1
Heart weight	0.2	0.2	0.6	-0.5	-0.8	0.3	0.3
Delay discount hyperbolic model param	0.9	1.2	2.3	-1.5	-0.9	1.3	-0.4
Intermittent access intake day 1-15 change	0.0	0.2	0.6	-0.8	-0.2	0.0	0.4
Intermittent access intake escalation	0.0	0.2	0.5	-0.7	-0.3	0.3	0.1
Intermittent access intake escalation 2	0.0	0.0	0.0	0.1	-0.1	0.0	-0.0
Intermitt. access day 1 inactive lever presses	0.0	0.0	0.1	0.3	-0.1	0.2	0.0
Intermitt. access day 15 inactive lever presses	0.1	0.3	0.9	0.3	0.4	0.4	-0.9
Intermitt. access escalation Index	0.0	0.0	0.1	0.3	-0.0	0.1	0.2
Intermittent access day 1 total infusions	0.9	2.8	4.3	1.1	2.1	-1.9	1.4
Intermittent access day 15 total infusions	0.5	1.2	2.2	0.4	1.5	-1.2	1.0
Intermittent access terminal intake (last 3 days)	0.7	1.2	2.6	0.6	1.6	-1.1	0.7
Intermittent access total infusions	1.5	1.8	3.8	0.8	1.9	-1.4	1.0
Intermittent access day 1 locomotion	0.7	1.3	2.4	1.1	1.6	-1.2	0.3
Intermittent access day 15 total locomotion	0.5	1.9	3.1	0.9	1.8	-1.5	1.1
Intermittent access total locomotion	1.3	1.5	2.6	0.9	1.6	-1.5	0.8
Intermittent access standard deviation	0.0	0.2	0.4	0.0	0.7	0.1	-0.5
Left kidney weight	4.2	33.8	60.0	-7.7	-6.7	5.0	-2.1
Right kidney weight	3.8	26.6	39.7	-6.3	-6.0	5.1	-2.2
Cocaine induced anxiety	0.1	0.2	0.4	-0.6	0.4	-0.3	-0.4
Post-drug Anxiety	1.1	1.3	2.7	1.2	1.7	-0.8	-0.6
Baseline Anxiety	1.5	2.5	7.5	2.7	1.4	0.0	-0.7
Tail length	1.3	6.9	19.1	-4.4	-1.8	0.4	2.3
Length with tail	5.6	24.8	60.6	-7.8	-5.2	3.4	0.2
Length without tail	5.8	30.6	46.8	-6.8	-6.6	5.1	-2.5
Times rat made contact with spout	0.5	0.5	1.8	0.2	0.3	-0.4	1.4
Lifetime Intake	1.4	1.7	3.7	0.8	1.9	-1.3	0.9
Liver weight, left	4.1	7.1	12.8	-3.2	-3.6	2.3	-0.5
Liver weight, right	2.8	4.9	8.7	-2.9	-2.8	1.7	-0.1
Locomotor activity	0.3	0.5	0.8	-0.8	-0.9	0.6	0.4
Locomotor testing distance	0.3	0.7	1.0	-0.8	-1.0	1.0	-0.2
Locomotor testing rearing	0.0	0.1	0.2	0.0	-0.4	0.2	-0.0
Locomotion in novel chamber	3.3	4.4	9.0	-0.0	1.6	-2.4	3.0
Locomotion in novel chamber post-restriction	1.0	3.1	9.0	-0.2	1.1	-1.5	3.0
Fecal boli incidents, locomotor time 1	0.2	0.5	0.9	-0.9	-0.7	0.7	-0.1
Change in fecal boli incidents, locomotor task	0.3	0.3	0.9	0.7	0.9	-0.2	-0.0
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.4	0.6	-0.1	-0.0	-0.3
Bouts of movement, locomotor time 1	0.5	0.6	1.6	-1.3	-0.9	0.3	0.1
Total resting periods, locomotor time 1	0.7	0.8	1.8	-1.3	-1.1	0.5	0.0
Rest time, locomotor task time 1	0.6	1.0	2.9	-1.7	0.5	-0.6	0.7
Distance moved, locomotor task time 1	0.1	0.3	1.1	1.1	-0.2	0.3	-0.2
Vertical activity count, locomotor time 1	0.1	0.7	1.3	0.2	-1.1	1.1	-0.4
Time >=10cm from walls, locomotor time 2	0.4	1.2	2.4	-1.0	-1.5	0.6	-0.9
Bouts of movement, locomotor time 2	0.8	2.6	5.4	-1.5	-2.3	1.5	-0.6
Total resting periods, locomotor time 2	0.7	2.8	5.0	-1.7	-2.2	1.7	-0.8
Rest time, locomotor task time 2	0.3	0.5	1.0	-0.8	1.0	-0.6	0.3
Distance moved, locomotor task time 2	0.3	0.5	1.1	0.8	-1.0	0.3	-0.1
Vertical activity count, locomotor time 2	0.3	0.8	1.9	-0.4	-1.4	1.0	0.1
Light reinforcement 1	0.2	0.9	2.1	1.5	0.9	-0.7	-0.3
Light reinforcement 2	0.2	0.4	0.7	0.9	0.7	0.1	-0.6
Bone: marrow area	0.3	0.6	1.1	-0.8	-1.0	0.2	0.9
Bone: maximum diameter	1.4	2.8	5.4	-1.9	-2.3	1.4	-0.6
Bone: maximum force	1.2	2.3	4.1	-2.0	-2.0	0.9	0.4
Bone: maximum moment	1.1	2.1	3.9	-1.9	-2.0	0.9	0.4
Mean time between licks in bursts	0.2	1.1	2.5	1.6	0.9	-1.0	0.3
Mean num. licks in bursts	0.2	0.6	1.2	-0.5	1.1	-0.9	0.3
Cd content in liver	1.4	1.6	2.6	1.0	1.3	-1.1	1.6
Co content in liver	1.8	2.1	4.2	0.7	2.0	-1.7	1.1
Cu content in liver	0.7	0.8	1.5	-0.2	-0.9	1.2	-1.0
Fe content in liver	6.5	8.1	11.0	-2.5	-3.3	3.3	-2.1
K content in liver	0.2	0.2	0.5	0.1	0.4	-0.7	0.2
Mg content in liver	0.5	0.5	1.5	0.1	1.2	-0.8	0.3
Mn content in liver	0.9	1.0	2.0	1.4	0.7	-1.0	0.8
Na content in liver	0.3	0.4	0.7	-0.8	-0.8	0.3	-0.3
Rb content in liver	0.7	0.8	1.8	1.3	0.7	-0.4	-0.9
Se content in liver	3.3	3.9	6.3	-2.0	-1.6	1.7	-2.5
Sr content in liver	0.2	0.2	0.7	-0.2	0.1	-0.2	0.8
Zn content in liver	1.3	1.5	3.3	-1.8	-1.0	1.3	-0.4
Bone: minimum diameter	0.1	0.1	0.2	0.5	-0.5	-0.1	0.2
Time in familiar zone, hab. session 1	0.4	0.4	1.3	0.2	-1.1	0.5	-0.4
Time in novel zone, hab. session 1	0.1	0.1	0.3	-0.2	0.0	0.6	0.0
Total zone transitions, hab. session 1	3.3	4.6	7.6	1.7	1.5	-2.8	2.4
Total locomotion distance, hab. session 1	0.8	1.2	3.0	0.6	0.5	-1.7	1.0
Locomotion velocity, hab. session 1	1.7	2.4	5.0	1.3	1.4	-2.2	1.1
Time in familiar zone, hab. session 2	2.0	2.2	3.4	0.2	-1.4	1.8	-1.9
Time in novel zone, hab. session 2	1.4	1.5	2.3	0.2	1.4	-1.5	1.3
Total zone transitions, hab. session 2	2.6	3.3	5.5	0.7	1.4	-2.3	2.3
Total locomotion distance, hab. session 2	2.3	3.1	5.6	0.8	1.4	-2.4	2.0
Locomotion velocity, hab. session 2	2.4	3.2	5.9	0.9	1.5	-2.4	2.0
Novel to familiar place preference ratio	0.8	1.0	2.1	1.2	1.4	-0.5	0.6
Novelty place preference	0.8	1.0	2.2	1.5	1.2	-0.3	0.3
Time in novel zone, NPP test	0.5	0.6	1.4	1.2	0.9	-0.1	0.2
Total zone transitions, NPP test	0.8	1.2	2.6	0.2	0.0	-1.5	1.6
Total locomotion distance, NPP test	1.2	1.6	3.7	0.1	0.7	-1.9	1.5
Locomotion velocity, NPP test	1.6	2.4	4.8	0.3	1.0	-2.2	1.9
Intraocular pressure	0.9	1.5	3.8	-1.9	-0.4	1.0	-0.9
Delta distance traveled before/after self-admin	0.8	0.9	1.8	-0.6	-0.3	-1.1	1.3
Delta ambulatory time before/after self-admin	0.2	0.4	0.9	-0.0	-0.1	-0.9	0.9
Parametrial fat weight	0.8	1.9	2.6	-0.9	-1.5	1.6	-1.4
Pavlov. Cond. lever latency	2.7	3.4	6.2	-1.0	-2.1	2.5	-1.4
Pavlov. Cond. magazine entry latency	1.5	1.9	4.4	-0.3	0.9	-1.5	2.1
Pavlov. Cond. change in total contacts	0.3	0.3	0.9	0.1	0.4	-1.0	0.5
Pavlov. Cond. index score	1.4	1.8	3.1	-0.1	1.3	-1.8	1.5
Pavlov. Cond. latency score	1.9	2.5	4.5	0.2	1.5	-2.1	1.8
Pavlov. Cond. lever contacts	2.6	3.1	5.6	0.9	2.1	-2.4	1.3
Pavlov. Cond. magazine entry number	0.9	1.2	2.6	0.2	-0.8	1.2	-1.6
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.4	-0.3	0.3	-0.2
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	2.7	-0.1	1.2	-1.6	1.4
Pavlov. Cond. response bias	1.4	1.7	2.6	-0.2	1.3	-1.6	1.6
Pavlov. Cond. lever latency	0.0	0.0	0.1	0.1	0.1	0.3	-0.2
Pavlov. Cond. magazine entry latency	0.6	0.9	3.0	1.7	0.5	-0.5	-0.0
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	0.3	-0.2	-0.1	-0.1
Pavlov. Cond. index score	0.2	0.3	0.6	0.8	0.3	-0.7	0.2
Pavlov. Cond. latency score	0.2	0.3	0.5	0.7	0.3	-0.6	0.2
Pavlov. Cond. lever contacts	0.0	0.0	0.0	-0.0	-0.0	-0.2	-0.1
Pavlov. Cond. magazine entry number	0.7	0.9	3.2	-1.8	-0.4	0.3	0.3
Pavlov. Cond. intertrial magazine entries	0.2	0.5	1.0	-1.0	-0.1	-0.2	1.0
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.9	0.9	0.3	-0.6	0.2
Pavlov. Cond. response bias	0.1	0.1	0.3	0.6	0.2	-0.3	-0.1
Time in closed arm before self-admin	0.1	0.2	0.6	-0.4	-0.3	0.2	0.7
Time in closed arm after self-admin	0.3	0.4	0.6	-0.2	-0.8	0.6	0.6
Time in open arm before self-admin	0.1	0.2	0.4	-0.2	-0.6	0.5	-0.0
Time in open arm after self-admin	0.9	1.0	1.3	1.1	1.2	-1.2	0.2
Bone: periosteal estimation	0.8	1.8	3.7	-1.6	-1.9	1.0	0.2
Bone: periosteal perimeter	1.8	3.5	7.1	-1.8	-2.7	1.6	-1.0
Bone: post-yield work	0.8	1.4	3.1	-1.8	-1.4	0.5	-0.5
Progressive ratio test 1 active lever presses	0.2	0.4	0.5	-0.5	0.7	-0.5	0.7
Progressive ratio test 1 breakpoint	0.2	0.4	0.6	-0.5	0.8	-0.5	0.7
Progressive ratio test 1 inactive lever presses	0.1	0.3	0.6	-0.0	0.8	-0.2	0.7
Progressive ratio test 2 active lever presses	0.7	1.0	1.7	-0.3	1.2	-0.9	1.3
Progressive ratio test 2 breakpoint	0.8	1.0	1.6	-0.2	1.2	-0.9	1.3
Progressive ratio test 2 inactive lever presses	0.2	0.7	1.3	-1.0	0.7	-0.2	1.1
Incentive Sensitization - Responses	0.3	0.9	1.4	0.4	1.2	-1.0	0.9
Incentive Sensitization - Breakpoint	0.4	0.9	1.5	0.4	1.2	-1.1	0.9
Sum of active levers in priming session hrs 5-6	0.7	0.7	1.4	-0.9	-1.2	0.4	-0.6
Progressive ratio	0.4	1.1	2.8	1.0	1.7	-0.7	0.5
Food seeking constrained by brief footshock	0.3	0.4	1.0	-0.0	-0.6	0.6	-1.0
Seeking ratio, punishment vs. effort	0.5	1.1	2.6	-1.0	-1.6	0.7	-0.4
Retroperitoneal fat weight	1.8	8.1	11.1	-1.6	-2.8	3.3	-3.3
Reaction time number correct	0.3	0.9	2.2	-0.8	-1.5	0.7	0.5
Reaction time mean minus median	0.5	3.4	6.5	1.0	2.6	-2.0	1.5
Reaction time mean minus median AUC	0.5	3.4	6.1	1.6	2.5	-1.9	1.3
Reaction time num false alarms	0.2	0.4	0.9	0.3	1.0	-0.6	0.3
Reaction time num false alarms AUC	0.0	0.1	0.1	-0.4	0.3	-0.0	-0.4
Reaction time trials correct on left	0.3	0.9	2.2	-0.8	-1.5	0.7	0.5
Reaction time trials on left	0.2	0.8	2.0	-0.7	-1.4	0.6	0.6
Reaction time mean	2.4	5.3	9.5	3.1	2.8	-1.9	0.6
Reaction time mean AUC	2.0	4.9	8.6	2.9	2.7	-1.8	0.5
Median of all reaction times	2.9	4.5	11.0	3.3	2.3	-1.4	0.1
Reaction time omissions	0.7	1.1	1.9	1.3	1.4	-0.9	0.2
Reaction time false alarm rate	0.2	0.3	0.9	0.0	0.9	-0.2	-0.6
Reaction time premature initiation rate	4.0	6.2	10.0	1.0	3.1	-3.2	2.0
Reaction time premature initiations	1.3	4.0	6.9	0.5	2.0	-2.6	2.2
Std. dev. reaction times	1.2	4.0	7.3	1.9	2.7	-2.0	1.1
Reaction time trials completed	0.2	0.8	2.0	-0.7	-1.4	0.6	0.6
Reaction time trials AUC	0.2	0.8	2.1	-0.7	-1.4	0.7	0.4
Run reversals in cocaine runway, females	0.6	0.7	1.1	0.8	1.0	-1.0	0.1
Run reversals in cocaine runway, males	0.7	0.8	1.4	-0.3	-1.2	1.1	-0.8
Latency to leave start box in cocaine runway	2.6	3.6	8.0	0.2	-0.8	2.4	-2.8
Latency to leave start box in cocaine runway, F	3.7	4.7	10.4	-0.4	-1.3	2.5	-3.2
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.5	-0.1	0.5	0.2
Std. dev. time between licks in bursts	0.0	0.0	0.1	0.1	0.0	-0.0	-0.2
Total sessions with >9 infusions	0.1	0.2	0.4	0.3	0.7	-0.4	-0.1
Short access day 1 total inactive lever presses	0.1	0.1	0.3	-0.5	0.4	-0.0	-0.1
Short access day 10 total inactive lever presses	0.1	0.5	1.8	-1.3	0.1	0.3	-0.5
Short access day 1 total infusions	0.1	0.3	0.5	0.4	0.7	-0.6	0.1
Short access day 10 total infusions	0.6	1.0	2.1	-0.1	1.4	-1.3	0.7
Short access total infusions	0.7	1.0	2.2	0.6	1.5	-1.1	0.5
Short access day 1 locomotion	0.8	1.3	2.5	1.6	1.4	-0.9	0.2
Short access day 10 total locomotion	0.1	0.2	0.7	-0.0	-0.1	0.3	-0.9
Short access total locomotion	0.6	0.9	1.5	1.2	1.2	-0.7	0.1
One hour access (0.3 mA shock)	2.5	3.0	4.4	0.5	2.0	-1.8	2.1
Compulsive drug intake	0.5	0.8	2.0	1.4	0.7	-0.8	0.4
One hour access (shock baseline)	0.4	1.0	1.9	-0.5	1.1	-0.8	1.4
Social response proportion	0.4	0.5	1.9	-0.4	-0.2	-0.3	1.4
Social responses	0.8	1.1	2.6	-0.7	0.5	-1.0	1.6
Social time	1.3	2.1	6.4	2.5	1.1	-0.5	0.4
Soleus weight	1.6	4.6	9.6	-3.1	-2.0	1.8	-1.2
Bone: stiffness	0.3	0.6	1.0	-1.0	-1.0	0.4	0.3
Tibialis anterior weight	2.5	8.6	21.7	-4.7	-3.0	1.9	-0.5
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.3	0.3	0.2	0.3	-0.6
Time to tail flick, vehicle, after self-admin	0.3	0.6	1.6	-0.4	-1.3	0.8	-0.1
Time to tail flick, test, before self-admin	1.1	1.2	2.5	-1.3	-1.6	0.8	-0.1
Time to tail flick, test, after self-admin	0.4	0.4	1.4	0.1	-0.3	0.6	-1.2
Delta time to tail flick, vehicle, before/after SA	0.9	1.0	2.1	-0.2	-1.4	1.1	-0.8
Delta time to tail flick, test, before/after SA	0.5	0.7	1.1	1.0	1.0	-0.7	-0.2
Tibia length	2.3	6.5	11.5	-2.6	-3.4	2.7	-0.6
Ambulatory time before self-admin	0.0	0.1	0.2	0.1	0.1	0.1	-0.5
Ambulatory time after self-admin	0.0	0.0	0.1	-0.3	-0.2	-0.2	-0.1
Bone: tissue strength	0.7	0.7	1.3	-1.0	-1.1	0.6	-0.3
Total heroin consumption	1.1	1.3	2.3	1.3	1.5	-1.1	0.2
Bone: trabecular number	4.8	9.0	15.1	-3.6	-3.9	2.6	-1.2
Bone: trabecular spacing	1.0	1.5	4.7	2.2	0.9	-0.5	-0.3
Bone: trabecular thickness	5.0	7.0	11.2	-3.4	-2.7	2.6	-1.7
Bone: trabecular tissue density	0.6	1.0	2.5	0.7	0.0	1.0	-1.6
Water consumed over 24 hours	0.3	0.6	1.9	-0.5	-0.2	-0.4	1.4
Number of responses in last shaping day	0.1	0.1	0.2	0.0	-0.1	0.3	-0.5