LOC134481143

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC134481143 0.75 0.12 1.3e-08 0.29 0.23 0.32 0.31 1.6e-07 3.2e-06 2.7e-08 3.6e-08
2 Eye gene expression LOC134481143 0.54 0.2 4.0e-03 0.26 0.19 0.2 0.2 7.2e-05 6.6e-04 6.2e-04 6.0e-04
3 Adipose gene expression LOC134481143 0.64 0.12 0.0e+00 0.25 0.26 0.3 0.28 3.7e-27 1.9e-28 1.6e-33 2.0e-31
4 Liver gene expression LOC134481143 0.67 0.12 0.0e+00 0.22 0.22 0.22 0.24 1.1e-23 2.6e-24 2.9e-24 3.5e-26
5 IL gene expression LOC134481143 0.72 0.13 9.7e-10 0.39 0.4 0.41 0.42 1.9e-10 1.2e-10 5.2e-11 3.1e-11
6 LHb gene expression LOC134481143 0.7 0.13 3.5e-08 0.32 0.29 0.31 0.32 2.9e-08 1.6e-07 4.9e-08 1.9e-08
7 PL gene expression LOC134481143 0.8 0.09 0.0e+00 0.43 0.52 0.54 0.54 1.8e-50 6.7e-67 2.2e-70 3.1e-70
8 BLA gene expression LOC134481143 0.58 0.14 3.6e-12 0.13 0.23 0.23 0.23 3.3e-07 1.5e-12 1.9e-12 2.6e-12
9 Brain gene expression LOC134481143 0.66 0.11 0.0e+00 0.36 0.42 0.42 0.43 7.8e-35 1.3e-41 1.3e-42 4.7e-43
10 pVTA gene expression LOC134481143 0.82 0.07 0.0e+00 0.44 0.59 0.62 0.61 2.0e-38 8.9e-59 8.2e-63 3.6e-61
11 IC gene expression LOC134481143 0.84 0.07 0.0e+00 0.39 0.5 0.5 0.53 2.1e-17 1.0e-23 9.0e-24 1.0e-25
12 NAcc gene expression LOC134481143 0.89 0.06 0.0e+00 0.49 0.53 0.55 0.54 4.0e-86 6.2e-95 1.3e-99 4.8e-99
13 RMTg gene expression LOC134481143 0.63 0.14 1.5e-05 0.23 0.23 0.2 0.2 7.2e-07 1.0e-06 6.5e-06 5.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density2.44.47.22.72.72.5-2.3-2.5-2.22.2-2.3-1.71.7-1.41.40.9
Area under the delay curve0.30.51.4-1.2-1.0-0.90.71.00.6-0.70.80.2-0.40.1-0.20.1
BMI with tail3.010.514.13.83.03.4-3.4-3.3-3.33.3-3.4-3.33.2-3.03.02.7
BMI without tail2.413.018.54.34.34.2-4.0-3.5-4.03.6-3.3-3.53.4-2.92.92.1
Body weight14.362.897.89.99.28.9-8.7-8.1-8.68.1-7.5-7.47.4-6.66.54.6
Weight adjusted by age0.41.11.91.11.11.2-1.1-1.2-0.81.3-1.4-0.61.1-1.01.10.6
Bone surface4.08.011.63.43.33.2-3.1-3.1-3.02.9-2.9-2.52.5-2.32.31.5
Bone volume2.44.86.62.62.42.4-2.4-2.5-2.32.3-2.4-2.02.0-1.81.81.3
Breakpoint value in progressive ratio session0.00.00.2-0.5-0.20.0-0.10.10.2-0.10.2-0.10.00.00.0-0.0
Number of licking bursts0.10.41.21.11.00.8-0.6-0.8-0.60.6-0.5-0.20.3-0.10.1-0.3
Context. condit. distance diff. score1.31.53.61.41.91.7-1.5-1.3-1.41.2-0.9-1.01.1-0.80.80.1
Locomotion velocity, session 10.50.60.9-0.8-0.9-0.60.90.80.9-0.80.90.8-0.60.7-0.6-0.5
Locomotion distance, session 12.02.63.6-1.9-1.8-1.61.71.71.7-1.61.61.5-1.51.5-1.4-1.1
Locomotion velocity, session 20.40.50.8-0.7-0.6-0.70.80.80.7-0.80.90.7-0.70.7-0.7-0.6
Locomotion distance, session 24.15.86.6-2.3-1.9-2.52.42.42.3-2.52.62.5-2.52.5-2.4-2.3
Locomotion velocity, session 30.00.00.10.40.30.2-0.2-0.2-0.20.2-0.1-0.20.2-0.10.20.0
Locomotion distance, session 30.30.40.6-0.7-0.4-0.50.60.40.6-0.60.50.7-0.70.8-0.7-0.8
Stereotopy head waving bouts, day 32.22.76.22.52.21.8-1.8-1.7-1.81.6-1.4-1.31.3-1.11.10.6
Stereotopy head waving duration, day 30.20.20.80.90.30.4-0.4-0.4-0.50.5-0.4-0.40.5-0.50.40.5
Locomotion velocity, session 70.20.20.7-0.8-0.8-0.30.40.60.5-0.40.50.1-0.0-0.00.00.2
Locomotion distance, session 70.91.11.8-0.9-0.8-1.01.01.21.0-1.11.41.0-1.01.0-1.0-1.0
Stereotopy head waving bouts, day 70.50.60.7-0.6-0.7-0.80.80.80.8-0.80.90.8-0.80.8-0.8-0.7
Stereotopy head waving duration, day 70.50.61.1-0.8-1.0-0.90.90.80.9-0.80.80.7-0.70.6-0.6-0.4
Locomotion velocity, session 80.10.10.30.20.30.5-0.4-0.2-0.40.4-0.2-0.40.5-0.40.40.4
Locomotion distance, session 80.30.41.00.81.00.8-0.8-0.6-0.70.6-0.4-0.50.5-0.40.40.0
Degree of sensitization distance0.91.01.7-0.9-1.1-1.21.11.31.0-1.11.20.9-0.90.8-0.8-0.6
Degree of sensitization stereotypy0.50.61.2-1.1-1.0-0.70.90.70.9-0.70.70.7-0.60.6-0.5-0.4
Conditioned locomotion0.10.10.10.20.10.4-0.2-0.3-0.20.3-0.3-0.10.3-0.20.20.2
Cocaine response after cond. corrected2.74.06.31.60.91.8-1.7-1.9-1.82.0-2.3-2.22.2-2.32.32.5
Cocaine response after cond. not corrected2.13.04.91.40.81.6-1.5-1.5-1.51.7-1.9-1.91.9-2.02.02.2
Cocaine response before conditioning0.70.81.5-0.7-0.4-0.70.71.10.8-0.91.21.0-0.90.9-0.9-1.2
Saline control response0.40.62.30.51.50.9-0.5-0.3-0.30.20.30.5-0.20.7-0.7-1.5
Bone: connectivity density3.86.111.43.13.43.1-2.8-2.8-2.72.5-2.4-2.02.0-1.61.60.9
Bone: cortical apparent density0.10.10.4-0.3-0.5-0.20.10.30.1-0.10.1-0.20.1-0.30.30.6
Bone: cortical area1.52.43.61.61.81.9-1.8-1.3-1.71.6-1.3-1.61.6-1.51.40.8
Bone: cortical porosity0.00.00.10.2-0.00.10.00.00.2-0.00.00.2-0.10.2-0.2-0.3
Bone: cortical porosity0.40.50.6-0.6-0.6-0.60.60.70.8-0.70.70.7-0.70.7-0.7-0.8
Bone: cortical thickness1.52.43.51.81.81.9-1.8-1.4-1.71.6-1.4-1.51.6-1.41.40.8
Bone: cortical thickness0.40.41.40.91.20.9-0.8-0.5-0.80.6-0.2-0.40.4-0.30.2-0.4
Bone: cortical tissue density0.10.10.3-0.4-0.6-0.30.20.30.2-0.20.1-0.10.0-0.20.20.6
Condit. Reinf. active minus inactive responses0.20.20.9-0.9-1.0-0.40.50.50.5-0.40.30.2-0.10.0-0.00.3
Condit. Reinf. active-inactive response ratio0.10.10.6-0.3-0.40.10.0-0.0-0.00.2-0.2-0.30.4-0.50.50.7
Condit. Reinf. active responses0.91.11.9-1.4-1.1-1.11.11.01.1-1.11.11.0-1.00.9-0.9-0.8
Condit. Reinf. inactive responses2.83.74.3-1.9-1.4-2.01.81.91.8-2.02.11.9-2.12.0-2.0-2.0
Incentive salience index mean0.70.91.9-1.4-1.2-1.01.01.01.1-1.01.00.8-0.80.7-0.8-0.6
Condit. Reinf. lever presses1.01.52.2-1.5-1.2-1.21.11.21.3-1.21.31.1-1.21.1-1.2-1.1
Condit. Reinf. active minus inactive responses0.10.20.70.20.80.7-0.5-0.2-0.40.30.2-0.10.3-0.10.0-0.3
Condit. Reinf. active-inactive response ratio0.00.10.3-0.10.20.10.00.30.1-0.20.50.2-0.10.3-0.3-0.5
Condit. Reinf. active responses0.10.20.80.10.90.9-0.5-0.1-0.40.30.2-0.10.30.0-0.0-0.4
Condit. Reinf. inactive responses0.10.10.40.00.50.6-0.3-0.2-0.20.20.0-0.00.20.0-0.0-0.3
Condit. Reinf. lever presses0.00.00.2-0.10.10.20.10.20.1-0.20.40.2-0.10.3-0.3-0.4
Condit. Reinf. lever reinforcers received0.10.10.5-0.30.50.4-0.10.30.0-0.10.60.3-0.10.4-0.4-0.7
Conditioned reinforcement - actives0.41.63.82.01.71.7-1.4-1.4-1.11.4-1.1-0.71.2-0.90.80.1
Conditioned reinforcement - inactives0.00.10.60.8-0.20.6-0.4-0.20.30.3-0.10.00.1-0.0-0.1-0.4
Conditioned locomotion0.71.14.52.11.81.4-1.1-0.8-1.20.7-0.2-0.50.4-0.1-0.0-0.6
Patch foraging indifference point 0 sec0.00.10.1-0.10.3-0.10.1-0.4-0.10.1-0.30.3-0.30.3-0.3-0.3
Patch foraging indifference point AUC0.20.51.50.30.81.2-1.0-0.8-0.40.9-0.9-0.40.8-0.50.60.2
Delay disc. indifference point, 0s delay4.04.57.91.61.32.1-2.0-1.6-2.32.0-1.7-2.82.4-2.42.42.4
Delay disc. indifference point, 16s delay0.20.30.8-0.4-0.5-0.70.70.90.6-0.70.70.7-0.50.2-0.3-0.3
Delay disc. indifference point, 2s delay0.50.61.8-1.3-1.3-0.80.71.00.4-0.60.8-0.3-0.1-0.10.10.6
Delay disc. indifference point, 24s delay0.50.81.3-1.2-1.0-0.91.01.00.9-0.90.90.7-0.80.7-0.7-0.4
Delay disc. indifference point, 4s delay0.20.20.9-0.7-0.9-0.40.20.50.2-0.30.5-0.50.0-0.10.10.4
Delay disc. indifference point, 8s delay0.81.32.2-1.5-1.2-1.41.01.21.2-1.21.20.9-1.10.8-0.9-0.9
Indifference point function ln k0.30.91.5-0.50.1-0.90.90.70.5-0.91.11.1-1.11.1-1.2-1.2
Indifference point function log k0.30.91.5-0.50.1-0.90.90.70.5-0.91.11.1-1.11.1-1.2-1.2
Patch foraging total patch changes 0 sec0.10.20.4-0.00.2-0.30.3-0.20.1-0.1-0.10.6-0.50.6-0.6-0.6
Patch foraging total patch changes 12 sec0.60.81.70.40.61.0-0.9-1.1-0.51.1-1.3-0.50.9-0.80.90.8
Patch foraging total patch changes 18 sec0.00.10.5-0.20.20.4-0.3-0.7-0.00.4-0.70.00.00.1-0.0-0.1
Patch foraging total patch changes 24 sec0.51.63.6-1.1-0.2-0.91.00.91.0-1.11.11.6-1.51.7-1.7-1.9
Patch foraging total patch changes 6 sec0.10.10.4-0.00.50.3-0.3-0.6-0.10.3-0.50.2-0.00.1-0.1-0.3
Patch foraging time to switch 0 sec0.83.29.11.5-0.20.6-1.1-1.1-1.51.3-1.8-2.51.9-2.42.43.0
Patch foraging water rate 0 sec0.41.46.0-0.11.20.10.2-0.10.2-0.50.81.3-1.21.7-1.8-2.4
Patch foraging water rate 12 sec0.52.25.8-0.90.1-1.01.01.10.8-1.41.61.5-1.71.9-2.1-2.4
Patch foraging water rate 18 sec1.73.87.3-1.3-0.6-1.61.61.91.3-2.12.41.8-2.22.3-2.4-2.7
Patch foraging water rate 24 sec0.50.83.90.61.20.3-0.2-0.1-0.3-0.20.60.4-0.71.1-1.2-2.0
Patch foraging water rate 6 sec0.91.34.40.30.5-0.50.60.50.2-1.01.21.0-1.41.7-1.7-2.1
Seeking ratio, delayed vs. immediate footshock0.40.51.5-0.4-0.5-1.21.00.60.3-0.90.60.6-1.00.7-0.7-0.2
Distance traveled before self-admin0.40.91.6-0.5-1.3-1.31.01.10.9-1.01.20.6-0.90.7-0.8-0.5
Distance traveled after self-admin1.01.84.6-2.1-1.6-1.01.11.21.8-1.11.31.3-1.01.1-1.1-1.2
Extensor digitorum longus weight3.112.524.04.54.94.5-4.1-3.6-3.93.6-3.0-3.03.1-2.62.40.9
Bone: elastic displacement0.10.10.30.40.50.5-0.4-0.5-0.30.3-0.3-0.10.2-0.10.1-0.2
Bone: elastic work2.02.65.12.02.32.1-1.9-1.8-1.71.7-1.5-1.21.3-1.01.00.1
Bone: endosteal estimation0.20.51.81.01.30.9-0.8-1.0-0.80.7-0.6-0.20.3-0.0-0.0-0.6
Bone: endosteal perimeter0.10.21.10.41.00.6-0.4-0.4-0.40.3-0.10.10.00.2-0.2-0.7
Epididymis fat weight0.00.10.2-0.1-0.3-0.30.30.40.4-0.10.30.3-0.10.1-0.1-0.2
Delta time in closed arm before/after self-admin0.10.10.4-0.10.10.0-0.00.1-0.1-0.30.5-0.2-0.20.6-0.5-0.6
Delta time in open arm before/after self-admin1.31.56.2-2.5-1.5-1.31.31.41.4-1.00.71.2-0.70.1-0.30.3
Diff in mean of infusions in LGA sessions0.00.00.2-0.40.10.2-0.10.00.20.1-0.10.20.1-0.10.1-0.1
Delay discount exponential model param0.91.22.81.71.41.4-1.1-1.4-1.01.2-1.2-0.60.8-0.50.50.3
Extinction: sum of active levers before priming0.20.43.5-1.9-0.5-0.30.20.40.4-0.10.10.20.1-0.20.20.4
Active lever presses in extinction session 60.00.00.20.4-0.00.3-0.2-0.20.10.2-0.20.00.2-0.20.10.0
Bone: final force2.03.25.52.02.42.2-2.1-1.8-2.01.8-1.6-1.61.7-1.51.40.6
Bone: final moment1.62.64.51.82.12.0-1.9-1.6-1.81.6-1.5-1.51.5-1.31.20.5
Food consumed during 24 hour testing period0.00.10.40.20.50.2-0.4-0.6-0.30.3-0.5-0.10.1-0.10.1-0.1
Glucose0.71.12.9-1.7-1.7-1.31.21.21.2-1.00.90.6-0.70.5-0.40.2
Heart weight0.71.13.50.00.1-0.60.50.80.5-1.01.40.8-1.11.4-1.5-1.9
Delay discount hyperbolic model param0.70.92.51.61.31.2-0.9-1.2-0.91.0-1.1-0.30.6-0.40.40.1
Intermittent access intake day 1-15 change0.10.71.30.70.71.1-1.0-1.0-0.31.1-1.1-0.40.8-0.70.70.3
Intermittent access intake escalation0.10.71.40.60.61.2-1.0-1.1-0.41.1-1.1-0.50.8-0.80.60.3
Intermittent access intake escalation 20.10.21.0-1.0-0.40.2-0.0-0.20.50.3-0.40.30.2-0.30.20.1
Intermitt. access day 1 inactive lever presses0.00.11.01.00.40.5-0.4-0.3-0.20.2-0.2-0.00.00.1-0.1-0.2
Intermitt. access day 15 inactive lever presses0.42.03.11.30.61.2-1.3-1.5-1.31.3-1.8-1.71.3-1.51.51.7
Intermitt. access escalation Index0.31.02.00.10.1-1.21.00.80.1-1.11.30.7-1.21.4-1.2-1.1
Intermittent access day 1 total infusions0.61.93.60.4-0.9-1.41.41.41.0-1.51.91.3-1.51.5-1.5-1.4
Intermittent access day 15 total infusions0.20.40.90.6-0.4-0.30.40.50.7-0.50.90.7-0.60.6-0.8-1.0
Intermittent access terminal intake (last 3 days)0.10.20.40.0-0.5-0.40.40.30.6-0.40.50.5-0.40.4-0.4-0.4
Intermittent access total infusions0.20.20.50.5-0.7-0.40.40.50.6-0.50.70.4-0.40.3-0.4-0.4
Intermittent access day 1 locomotion0.81.53.21.0-0.6-1.21.21.40.6-1.41.80.9-1.31.3-1.4-1.2
Intermittent access day 15 total locomotion0.52.14.41.9-0.1-0.81.01.10.6-1.31.91.2-1.51.8-1.9-2.1
Intermittent access total locomotion1.21.43.00.9-0.9-0.91.01.20.9-1.31.71.0-1.31.3-1.4-1.4
Intermittent access standard deviation0.31.62.91.70.71.3-1.2-1.4-1.01.3-1.6-1.31.2-1.31.21.2
Left kidney weight4.838.373.88.67.57.1-6.8-6.6-6.66.3-5.9-5.55.5-4.64.62.7
Right kidney weight5.034.961.97.96.86.8-6.5-6.4-6.36.1-5.7-5.55.3-4.74.52.8
Cocaine induced anxiety0.00.10.3-0.3-0.6-0.30.20.50.4-0.30.40.1-0.10.1-0.10.0
Post-drug Anxiety0.40.42.4-0.1-0.8-0.60.30.5-0.2-0.1-0.1-0.70.4-0.70.91.5
Baseline Anxiety0.40.63.00.70.1-0.30.0-0.1-0.90.1-0.7-0.90.6-0.91.11.7
Tail length4.524.344.86.06.76.1-5.6-5.0-5.55.0-4.3-4.24.5-3.63.61.9
Length with tail13.258.4100.810.09.89.0-8.5-7.9-8.47.8-6.9-6.66.9-5.75.73.3
Length without tail6.735.361.47.86.96.6-6.3-6.4-6.26.2-5.9-5.25.5-4.84.83.3
Times rat made contact with spout0.40.51.21.01.01.1-0.7-0.6-0.70.7-0.4-0.50.6-0.40.40.0
Lifetime Intake0.10.20.50.5-0.7-0.40.40.40.5-0.40.50.2-0.30.1-0.2-0.1
Liver weight, left2.44.27.52.72.72.4-2.3-2.5-2.12.2-2.3-1.41.6-1.21.20.6
Liver weight, right3.15.414.73.82.72.5-2.4-2.4-2.52.2-2.1-2.11.9-1.61.61.1
Locomotor activity0.30.52.50.50.90.4-0.10.20.1-0.20.80.7-0.40.8-0.9-1.6
Locomotor testing distance0.10.20.80.70.70.2-0.0-0.20.10.10.20.5-0.20.4-0.5-0.9
Locomotor testing rearing0.00.10.3-0.5-0.3-0.50.40.00.5-0.10.10.6-0.20.3-0.3-0.3
Locomotion in novel chamber0.91.33.61.91.40.10.00.1-0.7-0.71.00.3-1.11.4-1.5-1.9
Locomotion in novel chamber post-restriction0.20.73.50.20.90.20.00.30.1-0.50.80.6-0.81.3-1.2-1.9
Fecal boli incidents, locomotor time 10.20.41.40.11.11.2-1.0-0.6-0.60.4-0.2-0.30.10.0-0.1-0.7
Change in fecal boli incidents, locomotor task0.80.92.70.60.40.3-0.5-0.7-0.80.9-1.0-0.91.1-1.11.31.6
Time >=10cm from walls, locomotor time 10.81.07.7-2.8-1.6-0.20.40.70.8-0.20.2-0.10.3-0.40.40.9
Bouts of movement, locomotor time 10.30.41.90.51.40.4-0.9-0.8-0.90.4-0.5-0.60.2-0.00.1-0.3
Total resting periods, locomotor time 10.30.31.30.51.10.5-0.8-0.7-0.70.4-0.4-0.40.2-0.10.1-0.4
Rest time, locomotor task time 11.21.95.22.31.41.4-1.6-1.4-1.31.3-1.3-1.21.1-1.21.10.7
Distance moved, locomotor task time 10.61.72.9-1.7-1.4-1.11.41.51.5-1.21.31.4-1.01.1-1.1-0.9
Vertical activity count, locomotor time 10.21.66.7-2.6-0.7-0.90.91.21.2-1.01.11.3-0.91.1-1.0-1.2
Time >=10cm from walls, locomotor time 20.92.64.00.10.51.9-1.7-1.4-1.31.7-1.5-2.02.0-1.91.91.9
Bouts of movement, locomotor time 20.10.41.90.91.40.4-0.7-0.7-0.90.4-0.4-0.40.1-0.10.1-0.4
Total resting periods, locomotor time 20.20.62.41.11.60.5-0.8-0.8-1.10.6-0.6-0.60.3-0.40.3-0.1
Rest time, locomotor task time 20.10.10.60.2-0.1-0.80.40.20.1-0.30.10.2-0.30.2-0.10.1
Distance moved, locomotor task time 20.10.10.5-0.2-0.70.4-0.1-0.00.70.2-0.00.20.2-0.0-0.0-0.2
Vertical activity count, locomotor time 20.20.41.5-0.40.71.2-0.9-0.7-0.20.5-0.4-0.20.4-0.0-0.1-0.7
Light reinforcement 10.31.23.9-2.0-1.3-1.11.11.41.1-1.11.20.8-0.70.5-0.5-0.3
Light reinforcement 20.00.10.2-0.2-0.3-0.30.30.40.2-0.40.30.2-0.40.5-0.3-0.4
Bone: marrow area0.20.51.70.91.30.9-0.7-0.9-0.70.6-0.6-0.10.20.0-0.1-0.7
Bone: maximum diameter1.12.33.51.71.91.8-1.7-1.6-1.61.6-1.5-1.41.4-1.31.20.7
Bone: maximum force1.02.04.11.62.01.9-1.7-1.4-1.51.4-1.2-1.11.2-1.00.90.2
Bone: maximum moment0.81.53.31.51.81.7-1.5-1.2-1.41.3-1.1-1.01.0-0.80.80.1
Mean time between licks in bursts0.42.53.3-1.4-1.8-1.51.81.71.7-1.61.61.6-1.51.5-1.5-1.3
Mean num. licks in bursts0.00.00.1-0.3-0.2-0.0-0.00.1-0.00.00.0-0.10.1-0.20.20.3
Cd content in liver2.83.14.5-1.6-1.1-1.41.51.81.7-1.82.11.9-1.82.0-1.9-2.1
Co content in liver0.10.10.7-0.00.40.2-0.1-0.40.00.0-0.20.3-0.30.5-0.5-0.8
Cu content in liver0.30.40.6-0.7-0.8-0.60.60.30.8-0.50.40.6-0.50.7-0.5-0.4
Fe content in liver0.20.20.6-0.20.2-0.10.20.30.2-0.30.70.5-0.40.6-0.6-0.8
K content in liver0.50.50.70.40.30.5-0.6-0.7-0.60.7-0.8-0.80.8-0.80.90.8
Mg content in liver1.21.32.01.40.91.1-1.1-1.3-1.11.2-1.3-1.11.2-1.11.11.0
Mn content in liver0.00.00.1-0.3-0.2-0.10.1-0.10.00.0-0.2-0.10.0-0.10.10.1
Na content in liver1.31.41.81.31.31.2-1.2-1.1-1.31.2-1.2-1.21.2-1.11.11.1
Rb content in liver2.63.15.6-2.1-2.4-2.12.01.92.0-1.81.61.5-1.51.3-1.2-0.5
Se content in liver2.73.24.61.21.21.7-1.8-1.5-1.81.8-1.7-2.12.0-2.12.12.1
Sr content in liver0.20.20.30.60.60.5-0.4-0.6-0.40.4-0.6-0.20.2-0.10.1-0.1
Zn content in liver2.32.76.32.52.01.9-1.8-2.1-1.51.8-1.7-1.21.3-0.91.00.4
Bone: minimum diameter0.10.10.2-0.5-0.2-0.20.30.30.3-0.30.30.4-0.30.3-0.3-0.5
Time in familiar zone, hab. session 10.30.30.80.8-0.10.1-0.2-0.5-0.30.5-0.7-0.50.5-0.60.60.9
Time in novel zone, hab. session 10.10.10.6-0.10.50.8-0.5-0.3-0.40.4-0.2-0.30.4-0.20.2-0.0
Total zone transitions, hab. session 12.84.05.0-2.0-2.0-2.02.12.22.1-2.12.21.9-1.91.9-1.9-1.6
Total locomotion distance, hab. session 10.60.91.5-1.1-1.2-1.01.01.21.0-1.01.00.7-0.70.7-0.7-0.4
Locomotion velocity, hab. session 11.72.43.8-1.8-1.8-1.71.71.91.6-1.71.71.3-1.41.2-1.2-0.9
Time in familiar zone, hab. session 20.80.91.81.10.30.4-0.7-0.8-0.80.8-0.9-1.01.0-1.11.11.3
Time in novel zone, hab. session 21.41.53.1-1.8-0.9-0.81.11.11.2-1.11.21.3-1.21.3-1.3-1.3
Total zone transitions, hab. session 20.10.10.40.20.20.00.20.20.2-0.20.50.4-0.30.5-0.5-0.6
Total locomotion distance, hab. session 20.50.71.0-0.7-0.7-0.70.90.90.8-0.91.00.9-0.80.9-0.8-0.8
Locomotion velocity, hab. session 20.60.81.1-0.7-0.7-0.80.91.00.9-0.91.10.9-0.90.9-0.9-0.9
Novel to familiar place preference ratio0.10.20.4-0.7-0.3-0.30.40.40.4-0.40.50.4-0.40.4-0.4-0.5
Novelty place preference0.40.50.8-0.9-0.6-0.60.70.70.7-0.70.80.7-0.70.6-0.6-0.6
Time in novel zone, NPP test0.20.20.5-0.7-0.4-0.40.50.50.5-0.50.50.5-0.40.5-0.5-0.5
Total zone transitions, NPP test0.10.20.5-0.2-0.2-0.00.40.40.4-0.40.60.6-0.40.6-0.5-0.7
Total locomotion distance, NPP test0.30.40.7-0.7-0.6-0.40.70.80.6-0.60.90.6-0.40.5-0.5-0.5
Locomotion velocity, NPP test0.60.91.6-0.9-0.6-0.60.91.10.9-1.01.31.0-0.91.0-1.0-1.1
Intraocular pressure0.40.62.51.61.11.0-0.9-0.9-0.70.7-0.4-0.30.4-0.00.0-0.5
Delta distance traveled before/after self-admin0.20.32.3-1.5-0.10.20.10.00.60.0-0.10.6-0.10.2-0.2-0.4
Delta ambulatory time before/after self-admin0.40.74.5-2.1-0.7-0.50.70.51.0-0.40.30.9-0.50.5-0.4-0.4
Parametrial fat weight1.43.45.11.70.91.5-1.7-1.7-1.71.7-2.0-2.21.9-2.02.02.2
Pavlov. Cond. lever latency2.53.15.32.32.31.9-1.9-1.9-2.01.8-1.8-1.51.5-1.31.40.9
Pavlov. Cond. magazine entry latency0.00.00.20.20.4-0.1-0.30.0-0.2-0.10.1-0.1-0.1-0.0-0.1-0.3
Pavlov. Cond. change in total contacts0.20.20.5-0.6-0.7-0.60.10.50.2-0.30.1-0.30.0-0.40.30.6
Pavlov. Cond. index score0.20.20.4-0.6-0.6-0.60.40.50.4-0.50.50.2-0.40.2-0.2-0.2
Pavlov. Cond. latency score0.40.50.9-1.0-0.9-0.90.70.80.7-0.70.70.4-0.60.4-0.4-0.2
Pavlov. Cond. lever contacts1.51.83.8-1.8-2.0-1.51.51.51.5-1.41.31.0-1.10.9-0.9-0.4
Pavlov. Cond. magazine entry number0.10.10.2-0.1-0.20.30.0-0.2-0.00.3-0.4-0.10.3-0.30.30.5
Pavlov. Cond. intertrial magazine entries1.51.84.2-2.0-1.4-1.31.41.21.4-1.31.21.3-1.31.2-1.2-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.4-0.4-0.50.20.30.2-0.30.2-0.0-0.2-0.10.00.1
Pavlov. Cond. response bias0.10.10.2-0.2-0.2-0.50.20.40.3-0.40.50.2-0.40.3-0.3-0.5
Pavlov. Cond. lever latency0.50.71.21.00.70.8-0.8-1.1-0.90.9-1.1-0.80.8-0.70.70.7
Pavlov. Cond. magazine entry latency0.91.32.4-1.3-1.6-1.41.21.51.2-1.31.30.8-0.90.6-0.6-0.2
Pavlov. Cond. change in total contacts0.71.82.6-1.3-1.0-1.21.21.41.3-1.41.61.3-1.41.4-1.4-1.4
Pavlov. Cond. index score1.42.33.3-1.5-1.5-1.51.51.81.6-1.71.81.4-1.41.3-1.3-1.1
Pavlov. Cond. latency score1.11.72.6-1.4-1.4-1.31.41.61.4-1.41.61.2-1.21.1-1.1-0.9
Pavlov. Cond. lever contacts0.60.91.5-1.1-0.9-0.90.91.21.0-1.01.20.9-0.90.8-0.8-0.7
Pavlov. Cond. magazine entry number2.02.53.51.71.81.9-1.7-1.9-1.61.8-1.8-1.41.5-1.31.20.9
Pavlov. Cond. intertrial magazine entries0.10.20.90.50.90.7-0.5-0.5-0.50.4-0.2-0.10.20.0-0.1-0.5
Pavlov. Cond. lever-magazine prob. diff.1.72.63.7-1.6-1.6-1.71.61.91.6-1.81.91.5-1.51.4-1.4-1.2
Pavlov. Cond. response bias1.92.63.9-1.7-1.5-1.61.62.01.6-1.81.91.5-1.51.4-1.4-1.2
Time in closed arm before self-admin0.20.42.41.50.60.9-0.6-0.50.00.6-0.30.20.3-0.1-0.0-0.5
Time in closed arm after self-admin0.60.62.91.20.40.3-0.10.10.2-0.20.90.4-0.51.0-1.1-1.7
Time in open arm before self-admin0.20.30.7-0.20.0-0.60.40.4-0.0-0.60.80.1-0.40.8-0.6-0.6
Time in open arm after self-admin0.60.75.9-2.4-0.7-0.80.60.50.5-0.3-0.10.30.0-0.40.50.9
Bone: periosteal estimation0.81.84.01.62.01.7-1.6-1.4-1.51.4-1.2-1.11.1-0.90.80.0
Bone: periosteal perimeter0.10.10.60.20.80.6-0.4-0.1-0.40.20.1-0.10.2-0.00.0-0.4
Bone: post-yield work0.00.00.10.30.30.2-0.1-0.0-0.00.00.10.2-0.10.2-0.2-0.4
Progressive ratio test 1 active lever presses0.61.16.82.61.21.1-0.9-0.8-1.00.7-0.5-0.70.6-0.40.40.0
Progressive ratio test 1 breakpoint0.61.06.12.51.21.1-0.9-0.9-0.90.8-0.5-0.70.6-0.50.40.1
Progressive ratio test 1 inactive lever presses0.20.54.22.10.90.5-0.3-0.3-0.40.10.20.1-0.30.5-0.6-0.9
Progressive ratio test 2 active lever presses0.20.21.91.40.30.4-0.2-0.10.10.10.30.2-0.10.3-0.4-0.7
Progressive ratio test 2 breakpoint0.20.21.61.30.20.3-0.10.00.20.00.40.3-0.10.3-0.4-0.8
Progressive ratio test 2 inactive lever presses0.30.95.62.41.21.3-0.9-0.8-0.50.6-0.3-0.20.20.3-0.4-1.0
Incentive Sensitization - Responses0.10.30.9-0.6-0.9-0.40.50.60.9-0.40.40.6-0.30.3-0.3-0.3
Incentive Sensitization - Breakpoint0.20.41.1-0.7-1.0-0.60.60.81.1-0.50.60.8-0.40.4-0.5-0.4
Sum of active levers in priming session hrs 5-61.41.31.91.00.51.0-1.1-1.0-1.01.1-1.2-1.31.2-1.41.31.4
Progressive ratio0.10.20.5-0.2-0.3-0.60.40.3-0.1-0.70.5-0.1-0.70.7-0.6-0.2
Food seeking constrained by brief footshock0.30.41.1-0.9-1.0-0.80.70.30.8-0.50.10.6-0.60.5-0.40.0
Seeking ratio, punishment vs. effort0.20.40.70.50.50.7-0.6-0.6-0.10.8-0.8-0.10.8-0.70.70.4
Retroperitoneal fat weight0.62.66.11.00.30.9-1.1-1.2-1.31.5-1.8-1.91.8-2.12.22.5
Reaction time number correct0.10.31.20.00.5-0.00.30.00.3-0.20.30.9-0.60.8-0.8-1.1
Reaction time mean minus median0.00.21.1-1.1-0.0-0.10.20.80.1-0.40.70.10.00.00.0-0.2
Reaction time mean minus median AUC0.31.73.0-1.4-0.9-1.21.31.71.2-1.41.71.3-1.11.2-1.1-1.2
Reaction time num false alarms1.01.83.1-1.2-0.7-1.11.21.61.2-1.41.81.4-1.31.4-1.4-1.3
Reaction time num false alarms AUC0.51.12.1-0.7-0.5-0.80.91.20.9-1.11.51.1-1.11.2-1.2-1.2
Reaction time trials correct on left0.10.31.20.00.5-0.00.30.00.3-0.20.30.9-0.60.8-0.8-1.1
Reaction time trials on left0.10.31.20.00.5-0.00.30.10.3-0.30.30.9-0.60.8-0.8-1.1
Reaction time mean0.71.43.5-1.9-1.7-1.71.41.61.1-1.21.20.6-0.60.3-0.20.3
Reaction time mean AUC0.81.94.4-2.1-1.9-1.81.61.81.3-1.31.40.8-0.80.5-0.40.1
Median of all reaction times1.11.74.3-1.9-2.1-2.01.61.61.3-1.21.10.6-0.70.3-0.20.5
Reaction time omissions0.30.51.0-0.6-0.9-0.90.81.00.6-0.91.00.4-0.50.5-0.5-0.4
Reaction time false alarm rate0.50.61.6-0.5-0.6-0.70.71.10.6-0.91.30.6-0.70.8-0.8-0.6
Reaction time premature initiation rate0.10.20.5-0.70.4-0.40.20.5-0.3-0.50.6-0.0-0.30.3-0.4-0.4
Reaction time premature initiations0.10.30.6-0.50.6-0.40.30.4-0.2-0.50.70.4-0.60.6-0.7-0.8
Std. dev. reaction times0.10.41.3-0.9-0.7-0.90.71.10.5-0.71.00.3-0.20.2-0.10.0
Reaction time trials completed0.10.31.20.00.5-0.00.30.10.3-0.30.30.9-0.60.8-0.8-1.1
Reaction time trials AUC0.20.51.6-0.30.2-0.30.50.30.6-0.50.51.1-0.91.0-1.0-1.3
Run reversals in cocaine runway, females0.20.30.8-0.9-0.9-0.70.60.50.6-0.50.20.3-0.30.1-0.20.1
Run reversals in cocaine runway, males2.12.34.3-1.2-0.8-1.11.21.31.5-1.51.51.7-1.71.9-1.9-2.1
Latency to leave start box in cocaine runway0.30.41.10.40.30.3-0.5-0.4-0.60.6-0.7-0.80.6-0.80.91.1
Latency to leave start box in cocaine runway, F1.62.03.10.50.61.2-1.4-1.4-1.11.5-1.7-1.61.5-1.61.71.8
Latency to leave start box in cocaine runway, M0.70.61.00.30.0-0.90.90.90.3-0.91.00.8-1.00.9-0.9-0.8
Std. dev. time between licks in bursts0.30.62.0-0.4-0.1-0.30.50.80.6-0.71.00.9-0.81.0-1.0-1.4
Total sessions with >9 infusions0.30.42.81.70.20.2-0.3-0.3-0.50.3-0.4-0.60.2-0.40.40.6
Short access day 1 total inactive lever presses0.50.93.11.81.10.8-0.8-1.0-1.20.8-1.0-0.90.6-0.60.60.6
Short access day 10 total inactive lever presses0.75.17.82.82.02.4-2.3-2.6-2.22.3-2.8-2.12.1-1.91.91.7
Short access day 1 total infusions0.10.10.50.6-0.4-0.40.20.0-0.1-0.1-0.2-0.20.0-0.20.30.7
Short access day 10 total infusions0.10.10.7-0.3-0.8-0.40.40.30.6-0.30.10.2-0.20.1-0.00.2
Short access total infusions0.20.31.00.9-0.2-0.0-0.1-0.2-0.30.2-0.4-0.60.3-0.70.61.0
Short access day 1 locomotion0.30.61.40.7-0.2-0.90.80.90.2-0.91.20.4-0.80.9-0.8-0.6
Short access day 10 total locomotion0.10.54.62.10.60.00.0-0.1-0.5-0.10.10.0-0.40.5-0.4-0.4
Short access total locomotion0.10.20.70.8-0.2-0.40.40.5-0.1-0.50.5-0.0-0.40.3-0.20.1
One hour access (0.3 mA shock)1.21.43.4-0.6-0.5-0.40.80.91.5-0.71.21.8-1.01.3-1.4-1.8
Compulsive drug intake2.02.98.0-2.8-1.9-1.91.81.71.8-1.61.51.6-1.41.3-1.2-0.8
One hour access (shock baseline)0.10.42.01.40.70.7-0.3-0.10.10.10.40.4-0.10.4-0.5-1.1
Social response proportion2.43.16.62.42.62.1-2.1-1.6-2.21.6-1.1-1.71.4-1.21.10.4
Social responses0.40.51.81.31.40.8-0.6-0.2-0.60.10.30.0-0.20.4-0.5-1.1
Social time2.54.05.6-2.1-2.0-2.22.12.42.1-2.12.31.9-1.91.6-1.7-1.2
Soleus weight0.61.64.51.32.11.8-1.6-1.4-1.51.3-1.1-0.90.9-0.70.5-0.4
Bone: stiffness0.10.10.40.20.70.5-0.30.1-0.20.10.30.00.10.1-0.1-0.6
Tibialis anterior weight5.217.929.05.25.45.2-4.9-4.2-4.64.3-3.8-3.83.9-3.53.31.8
Time to tail flick, vehicle, before self-admin0.30.31.5-1.2-0.6-0.2-0.00.30.00.0-0.0-0.50.4-0.60.60.9
Time to tail flick, vehicle, after self-admin0.10.20.4-0.0-0.6-0.40.40.40.7-0.30.50.4-0.20.3-0.3-0.4
Time to tail flick, test, before self-admin0.70.81.50.91.11.2-1.0-1.2-0.81.0-1.1-0.70.9-0.60.70.3
Time to tail flick, test, after self-admin0.20.20.70.80.4-0.2-0.0-0.1-0.70.2-0.3-0.50.3-0.40.50.7
Delta time to tail flick, vehicle, before/after SA0.60.71.4-0.5-0.9-0.70.80.71.2-0.70.81.1-0.70.8-0.8-0.9
Delta time to tail flick, test, before/after SA0.30.41.2-0.5-0.8-1.10.80.80.4-0.60.60.4-0.50.3-0.30.1
Tibia length6.217.228.05.34.44.5-4.4-4.2-4.24.3-4.1-3.94.0-3.73.62.8
Ambulatory time before self-admin0.20.61.2-0.3-0.9-0.90.80.90.7-0.81.10.6-0.70.6-0.7-0.7
Ambulatory time after self-admin1.11.75.4-2.3-1.7-1.11.11.21.8-1.01.11.3-0.90.9-0.9-0.9
Bone: tissue strength0.10.10.40.50.10.2-0.2-0.5-0.10.3-0.6-0.10.2-0.20.20.2
Total heroin consumption3.64.39.5-2.5-3.1-2.22.12.22.6-2.02.11.6-1.61.5-1.4-1.0
Bone: trabecular number2.24.26.72.52.62.4-2.3-2.3-2.22.1-2.1-1.71.7-1.51.41.1
Bone: trabecular spacing1.72.44.6-2.1-2.1-1.91.81.61.7-1.61.41.3-1.41.1-1.1-0.6
Bone: trabecular thickness2.73.86.32.32.52.4-2.2-2.1-2.12.0-1.9-1.71.7-1.51.40.7
Bone: trabecular tissue density0.10.10.3-0.20.00.3-0.30.4-0.20.10.3-0.50.5-0.50.50.4
Water consumed over 24 hours0.81.64.01.72.01.6-1.5-1.5-1.41.3-1.2-0.80.9-0.60.60.0
Number of responses in last shaping day0.10.10.40.6-0.5-0.30.10.20.1-0.20.2-0.3-0.10.1-0.10.1