Hub : Genes

LOC134480889

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC134480889 0.32 0.13 2.1e-04 0.1 0.08 0.14 0.15 1.8e-03 5.9e-03 4.3e-04 2.5e-04
2 IL gene expression LOC134480889 0.18 0.11 8.3e-03 0.06 0.09 0.09 0.07 1.6e-02 3.9e-03 4.2e-03 8.1e-03
3 IC gene expression LOC134480889 0.28 0.1 9.1e-12 0.17 0.25 0.26 0.22 1.7e-07 5.2e-11 2.4e-11 7.5e-10
4 Brain gene expression LOC134480889 0.07 0.04 1.9e-06 0.04 0.07 0.06 0.06 1.2e-04 8.6e-07 5.5e-06 3.6e-06
5 PL gene expression LOC134480889 0.08 0.04 1.8e-08 0.07 0.07 0.08 0.08 3.7e-08 1.3e-08 6.6e-09 1.1e-08
6 pVTA gene expression LOC134480889 0.05 0.03 6.0e-04 0.01 0.02 0.02 0.01 9.2e-02 7.4e-03 1.1e-02 3.7e-02
7 Brain intron excision ratio chr10_90974697_91027769 0.04 0.02 2.2e-03 0.02 0.02 0.02 0.02 7.4e-03 2.4e-03 4.2e-03 2.2e-03
8 IC intron excision ratio chr10_90974697_91027769 0.1 0.06 1.8e-03 0 0.02 0 0.01 2.2e-01 3.6e-02 2.1e-01 1.8e-01
9 NAcc intron excision ratio chr10_90993514_90997198 0.03 0.01 1.6e-03 0.02 0.01 0.01 0.01 4.7e-04 2.4e-03 4.3e-03 7.0e-03
10 BLA gene expression LOC134480889 0.11 0.06 1.2e-04 0.05 0.08 0.06 0.06 9.1e-04 4.9e-05 6.6e-04 5.5e-04
11 NAcc gene expression LOC134480889 0.09 0.04 1.4e-15 0.1 0.11 0.1 0.11 7.8e-15 2.4e-16 3.4e-15 1.0e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.41.5-0.6-1.2-0.6-0.3-0.50.20.80.2-1.00.00.1
Area under the delay curve0.30.31.2-0.2-0.6-0.6-0.2-0.5-0.20.60.5-1.1-0.7-0.6
BMI with tail2.69.018.0-1.8-1.9-3.5-2.2-3.1-3.02.03.2-2.9-4.2-4.0
BMI without tail3.911.820.4-2.4-2.7-4.0-2.7-3.7-3.32.04.1-3.2-4.5-4.1
Body weight5.624.533.2-3.8-4.5-5.5-4.5-5.3-4.93.95.2-4.9-5.8-5.6
Weight adjusted by age0.20.21.50.1-0.10.0-0.2-0.1-0.20.8-0.1-1.2-0.3-0.5
Bone surface4.37.713.0-3.1-3.6-2.9-3.0-2.7-2.33.41.9-3.3-1.8-2.1
Bone volume3.05.410.0-2.3-3.2-2.5-2.4-2.4-1.72.71.7-2.8-1.6-1.7
Breakpoint value in progressive ratio session0.20.20.9-1.0-0.30.1-0.60.4-0.50.6-0.00.00.30.1
Number of licking bursts0.10.20.4-0.4-0.4-0.3-0.5-0.3-0.40.60.1-0.5-0.3-0.4
Context. condit. distance diff. score0.20.20.70.30.90.30.40.40.1-0.6-0.20.6-0.1-0.1
Locomotion velocity, session 10.60.61.7-1.1-1.3-0.6-0.9-0.9-0.50.70.7-0.8-0.2-0.2
Locomotion distance, session 10.10.10.10.3-0.30.30.1-0.10.4-0.10.1-0.20.30.4
Locomotion velocity, session 20.30.41.1-1.0-0.50.5-0.70.2-0.30.5-0.20.20.90.7
Locomotion distance, session 20.40.51.20.10.51.10.30.80.4-0.4-0.60.71.01.0
Locomotion velocity, session 30.10.10.40.2-0.30.3-0.00.20.30.2-0.4-0.20.60.4
Locomotion distance, session 30.20.20.8-0.2-0.7-0.2-0.6-0.2-0.20.9-0.2-0.70.2-0.2
Stereotopy head waving bouts, day 30.50.61.40.80.40.60.90.71.2-0.8-0.70.40.91.0
Stereotopy head waving duration, day 30.60.71.30.80.70.71.00.71.0-1.2-0.40.90.70.9
Locomotion velocity, session 70.60.60.90.70.50.90.80.90.9-0.5-0.90.40.90.9
Locomotion distance, session 70.20.30.40.50.60.60.60.60.5-0.5-0.50.40.40.5
Stereotopy head waving bouts, day 70.91.12.10.70.61.10.81.11.2-0.6-1.30.81.41.3
Stereotopy head waving duration, day 72.93.55.71.31.52.11.62.01.8-1.4-2.01.92.42.3
Locomotion velocity, session 80.91.12.3-1.0-0.8-0.8-1.4-1.0-1.50.71.3-0.5-1.0-1.0
Locomotion distance, session 80.40.61.60.31.01.00.50.80.2-1.0-0.21.30.50.7
Degree of sensitization distance0.20.20.80.20.70.20.50.10.1-0.90.40.6-0.4-0.0
Degree of sensitization stereotypy1.41.52.80.80.91.40.91.41.2-0.6-1.61.01.71.4
Conditioned locomotion0.10.10.50.10.40.10.30.3-0.0-0.60.30.7-0.20.2
Cocaine response after cond. corrected0.70.93.2-0.4-1.0-0.9-0.7-0.8-0.41.4-0.1-1.8-0.6-1.1
Cocaine response after cond. not corrected0.91.13.5-0.7-1.3-0.6-1.0-0.5-0.31.9-0.7-1.90.1-0.7
Cocaine response before conditioning0.30.41.6-0.2-0.20.6-0.10.50.40.3-0.90.31.31.0
Saline control response0.81.12.4-1.5-0.3-0.9-1.0-0.8-1.50.31.50.2-1.2-0.9
Bone: connectivity density0.40.61.8-1.1-1.3-0.7-0.6-0.5-0.21.10.3-1.0-0.00.0
Bone: cortical apparent density6.48.712.93.62.72.83.42.93.4-3.1-2.32.52.62.9
Bone: cortical area2.64.08.3-1.3-2.5-2.2-1.8-2.2-1.22.41.1-2.9-1.6-1.9
Bone: cortical porosity16.918.230.8-4.8-5.1-4.1-5.0-4.0-4.05.62.3-4.8-2.6-3.6
Bone: cortical porosity15.116.425.6-4.1-4.7-4.1-4.6-4.0-3.85.12.4-4.7-2.8-3.7
Bone: cortical thickness1.83.08.02.80.91.12.11.12.7-0.6-2.4-0.51.61.2
Bone: cortical thickness2.22.65.21.90.91.51.71.62.2-0.6-2.30.31.91.6
Bone: cortical tissue density6.38.612.43.52.72.93.42.93.4-3.1-2.32.52.62.9
Condit. Reinf. active minus inactive responses1.92.14.4-2.1-1.6-1.4-1.7-1.3-1.71.41.4-0.9-1.0-1.0
Condit. Reinf. active-inactive response ratio0.60.62.1-1.5-0.7-0.8-0.9-0.5-0.91.00.4-0.5-0.4-0.5
Condit. Reinf. active responses1.62.03.8-2.0-1.6-1.3-1.7-1.4-1.71.01.8-0.6-1.1-0.9
Condit. Reinf. inactive responses0.40.41.8-0.5-0.8-0.5-0.6-0.8-0.7-0.11.3-0.1-0.6-0.3
Incentive salience index mean1.31.63.7-1.9-1.6-1.1-1.6-1.1-1.41.51.0-0.9-0.6-0.7
Condit. Reinf. lever presses0.10.10.4-0.5-0.6-0.1-0.50.0-0.20.5-0.0-0.00.40.4
Condit. Reinf. active minus inactive responses3.64.69.1-3.0-2.7-2.0-2.5-2.1-2.12.51.6-1.8-1.3-1.4
Condit. Reinf. active-inactive response ratio2.83.26.8-2.6-2.2-1.6-2.1-1.6-1.72.31.1-1.6-0.9-1.1
Condit. Reinf. active responses3.44.88.6-2.9-2.6-2.1-2.5-2.2-2.32.12.3-1.5-1.5-1.4
Condit. Reinf. inactive responses0.40.52.4-0.7-0.7-0.5-0.7-0.8-0.9-0.21.50.3-0.6-0.2
Condit. Reinf. lever presses1.11.53.0-1.7-1.5-1.1-1.5-1.2-1.31.31.1-0.8-0.6-0.7
Condit. Reinf. lever reinforcers received3.14.37.8-2.8-2.5-2.0-2.4-2.1-2.12.02.1-1.5-1.5-1.4
Conditioned reinforcement - actives0.50.91.9-0.8-0.6-1.0-0.8-0.9-1.10.51.4-0.6-1.3-1.1
Conditioned reinforcement - inactives1.42.02.6-1.4-1.4-1.6-1.3-1.3-1.31.31.3-1.4-1.6-1.6
Conditioned locomotion2.93.74.5-2.1-1.8-2.0-1.9-1.8-2.01.62.1-1.6-2.1-2.0
Patch foraging indifference point 0 sec1.01.84.6-1.6-1.3-1.4-1.1-1.5-1.40.42.2-0.3-1.5-0.9
Patch foraging indifference point AUC0.30.51.4-0.6-0.4-0.7-0.5-0.8-0.80.11.2-0.2-1.0-0.7
Delay disc. indifference point, 0s delay0.50.51.30.70.60.90.71.10.7-0.5-0.50.40.70.8
Delay disc. indifference point, 16s delay2.02.24.1-0.9-1.3-1.6-1.1-1.5-1.11.41.3-2.0-1.8-1.7
Delay disc. indifference point, 2s delay0.10.10.4-0.1-0.6-0.0-0.10.00.10.20.4-0.50.00.2
Delay disc. indifference point, 24s delay2.02.34.0-0.9-1.4-1.6-1.2-1.7-1.30.82.0-1.4-2.0-1.7
Delay disc. indifference point, 4s delay0.40.41.8-0.2-0.5-0.0-0.30.10.11.2-0.5-1.40.2-0.2
Delay disc. indifference point, 8s delay0.20.20.70.70.10.20.70.20.8-0.5-0.3-0.00.20.4
Indifference point function ln k0.10.20.40.3-0.30.30.20.40.60.1-0.5-0.30.60.5
Indifference point function log k0.10.20.40.3-0.30.30.20.40.60.1-0.5-0.30.60.5
Patch foraging total patch changes 0 sec1.42.65.4-1.8-1.7-1.7-1.5-1.8-1.60.72.3-0.7-1.7-1.3
Patch foraging total patch changes 12 sec0.71.03.6-1.3-0.4-0.7-0.7-0.8-1.2-0.31.90.7-1.0-0.3
Patch foraging total patch changes 18 sec1.72.74.1-2.0-1.3-1.8-1.6-1.8-1.81.21.7-1.1-1.7-1.6
Patch foraging total patch changes 24 sec0.91.63.2-1.6-1.3-1.3-1.1-1.4-1.20.61.8-0.6-1.2-0.9
Patch foraging total patch changes 6 sec1.11.72.8-1.6-1.3-1.5-1.3-1.6-1.40.81.7-0.6-1.3-1.1
Patch foraging time to switch 0 sec0.10.10.60.20.20.40.00.30.20.3-0.8-0.00.60.3
Patch foraging water rate 0 sec0.91.93.6-1.2-1.5-1.6-1.2-1.5-1.30.71.9-1.0-1.7-1.4
Patch foraging water rate 12 sec0.10.31.20.4-0.6-0.3-0.0-0.30.50.6-0.6-1.10.1-0.4
Patch foraging water rate 18 sec0.20.20.60.3-0.30.40.30.50.7-0.1-0.60.20.80.7
Patch foraging water rate 24 sec0.00.00.10.2-0.1-0.0-0.00.10.10.2-0.4-0.10.1-0.1
Patch foraging water rate 6 sec0.10.10.5-0.2-0.6-0.4-0.1-0.20.20.40.1-0.7-0.1-0.2
Seeking ratio, delayed vs. immediate footshock0.20.30.7-0.30.1-0.4-0.3-0.0-0.60.40.5-0.6-0.9-0.8
Distance traveled before self-admin0.50.72.0-0.7-1.0-0.4-1.0-0.5-0.51.4-0.2-1.2-0.0-0.6
Distance traveled after self-admin0.10.10.4-0.4-0.0-0.0-0.40.1-0.30.6-0.4-0.10.1-0.2
Extensor digitorum longus weight0.62.36.22.52.40.41.70.70.5-2.50.41.4-1.2-0.6
Bone: elastic displacement0.60.71.91.10.20.60.70.61.20.0-1.4-0.41.00.6
Bone: elastic work0.50.62.20.1-1.1-0.8-0.5-0.8-0.01.10.0-1.5-0.3-0.6
Bone: endosteal estimation12.828.143.1-6.6-5.5-5.2-6.0-5.2-5.85.34.8-4.3-4.4-4.6
Bone: endosteal perimeter17.938.146.2-6.8-6.3-6.3-6.7-6.3-6.66.05.7-5.4-5.7-5.9
Epididymis fat weight0.51.83.0-1.0-1.0-1.4-1.1-1.7-1.30.61.7-1.1-1.7-1.4
Delta time in closed arm before/after self-admin0.20.21.00.50.10.20.40.10.70.2-1.0-0.10.50.3
Delta time in open arm before/after self-admin1.01.03.30.81.10.90.80.80.3-1.80.61.60.20.8
Diff in mean of infusions in LGA sessions1.21.42.61.21.41.51.21.61.1-0.8-1.10.71.21.2
Delay discount exponential model param0.40.51.30.30.70.70.40.60.4-0.7-0.71.10.80.7
Extinction: sum of active levers before priming0.10.10.20.00.50.30.20.4-0.1-0.30.30.2-0.10.1
Active lever presses in extinction session 61.61.62.8-1.7-1.3-1.2-1.4-1.1-1.41.21.2-1.0-1.1-1.2
Bone: final force1.21.84.6-0.8-1.8-1.5-1.1-1.6-0.51.90.3-2.1-0.8-1.1
Bone: final moment1.21.94.8-0.8-2.0-1.5-1.2-1.6-0.52.00.2-2.2-0.7-1.1
Food consumed during 24 hour testing period2.73.76.2-1.7-1.4-2.1-1.7-2.3-2.21.02.5-1.2-2.4-2.0
Glucose0.10.10.30.40.20.1-0.00.10.10.3-0.6-0.40.1-0.3
Heart weight0.61.02.7-0.0-0.6-1.3-0.4-1.2-0.40.90.3-1.6-1.3-1.4
Delay discount hyperbolic model param0.40.41.20.40.70.60.40.60.3-0.7-0.61.10.70.6
Intermittent access intake day 1-15 change0.30.61.2-0.6-0.4-0.6-0.9-0.5-1.01.10.4-1.0-0.8-1.0
Intermittent access intake escalation0.91.82.7-1.1-1.0-1.3-1.4-1.1-1.61.60.9-1.6-1.4-1.7
Intermittent access intake escalation 21.61.82.6-1.2-1.0-1.3-1.4-1.1-1.51.60.9-1.5-1.4-1.6
Intermitt. access day 1 inactive lever presses0.52.03.2-1.8-1.8-1.4-1.6-1.4-1.41.21.5-0.9-1.2-1.0
Intermitt. access day 15 inactive lever presses0.61.22.3-1.2-1.5-1.1-1.1-1.2-1.00.91.3-0.8-1.0-0.9
Intermitt. access escalation Index0.60.92.30.91.20.90.91.20.9-0.4-1.50.40.90.6
Intermittent access day 1 total infusions0.30.50.9-1.0-0.8-0.6-0.8-0.6-0.80.30.9-0.2-0.6-0.6
Intermittent access day 15 total infusions2.53.85.7-1.8-1.4-2.0-1.8-1.9-2.21.52.1-1.7-2.4-2.3
Intermittent access terminal intake (last 3 days)3.24.25.8-2.1-1.7-2.1-2.0-1.9-2.41.62.4-1.6-2.4-2.2
Intermittent access total infusions1.92.34.1-1.6-1.2-1.5-1.5-1.4-1.80.82.0-0.8-1.8-1.6
Intermittent access day 1 locomotion3.14.05.5-2.3-2.1-2.1-2.1-2.1-2.11.62.1-1.4-2.0-1.9
Intermittent access day 15 total locomotion2.74.97.0-2.5-1.8-2.4-2.2-2.1-2.61.52.6-1.3-2.6-2.3
Intermittent access total locomotion4.85.78.0-2.8-2.3-2.5-2.5-2.4-2.71.82.8-1.6-2.5-2.2
Intermittent access standard deviation0.20.30.7-0.6-0.5-0.5-0.6-0.5-0.70.30.8-0.2-0.6-0.5
Left kidney weight0.10.21.30.2-0.3-0.20.1-0.10.40.7-0.6-1.20.1-0.2
Right kidney weight0.10.62.5-0.2-0.8-0.8-0.4-0.7-0.11.1-0.1-1.6-0.6-0.8
Cocaine induced anxiety0.30.41.30.70.30.20.70.01.0-0.5-1.10.50.80.5
Post-drug Anxiety0.20.20.80.50.1-0.00.4-0.20.70.1-0.9-0.30.40.1
Baseline Anxiety0.20.31.2-0.2-0.2-0.3-0.4-0.2-0.40.70.3-1.1-0.6-0.6
Tail length1.76.510.3-2.8-3.2-2.5-2.8-2.7-2.52.22.8-2.2-2.0-1.9
Length with tail1.98.310.4-2.7-3.2-3.0-3.1-3.1-2.92.53.1-2.7-2.7-2.6
Length without tail0.41.31.9-0.8-0.9-1.3-1.0-1.2-1.11.11.0-1.3-1.4-1.4
Times rat made contact with spout0.70.81.1-1.0-0.8-1.1-0.9-0.9-0.90.80.7-0.7-0.8-0.9
Lifetime Intake2.12.64.5-1.7-1.4-1.6-1.6-1.5-1.90.92.1-0.9-1.9-1.6
Liver weight, left3.05.09.0-3.0-2.6-2.0-2.7-2.0-2.32.71.5-2.0-1.3-1.6
Liver weight, right0.50.82.31.1-0.10.70.70.71.40.3-1.5-0.51.10.7
Locomotor activity0.10.20.7-0.8-0.2-0.2-0.5-0.2-0.6-0.10.40.5-0.0-0.0
Locomotor testing distance0.50.92.4-1.6-0.8-0.9-1.1-1.1-1.20.50.9-0.0-0.6-0.7
Locomotor testing rearing0.40.83.4-1.8-0.2-0.7-1.1-0.6-1.30.50.50.3-0.5-0.5
Locomotion in novel chamber0.81.03.4-0.9-1.1-0.6-1.2-0.2-0.61.8-0.3-1.7-0.1-0.9
Locomotion in novel chamber post-restriction0.81.32.1-1.2-1.2-1.3-1.1-1.4-1.10.61.4-0.6-1.2-1.1
Fecal boli incidents, locomotor time 10.10.10.5-0.0-0.3-0.3-0.3-0.7-0.3-0.30.40.3-0.4-0.5
Change in fecal boli incidents, locomotor task0.10.10.30.60.2-0.20.4-0.10.2-0.20.2-0.5-0.4-0.2
Time >=10cm from walls, locomotor time 11.31.43.31.01.31.21.01.31.1-0.5-1.81.01.40.9
Bouts of movement, locomotor time 10.40.40.80.90.60.50.80.60.8-0.9-0.40.50.30.5
Total resting periods, locomotor time 10.30.40.80.90.50.40.80.50.8-0.8-0.40.20.30.4
Rest time, locomotor task time 10.50.71.00.70.40.70.80.71.0-0.9-0.70.90.91.0
Distance moved, locomotor task time 10.71.01.7-0.8-0.7-1.1-0.9-1.0-1.01.10.8-1.3-1.1-1.1
Vertical activity count, locomotor time 10.51.22.5-0.8-1.1-1.1-1.1-0.9-0.91.40.7-1.6-0.9-1.1
Time >=10cm from walls, locomotor time 20.40.62.7-0.9-0.6-0.3-0.8-0.1-0.41.6-0.7-1.10.2-0.4
Bouts of movement, locomotor time 20.00.00.40.60.10.00.2-0.00.2-0.1-0.1-0.1-0.0-0.0
Total resting periods, locomotor time 20.10.20.80.90.40.20.50.10.5-0.3-0.40.10.20.2
Rest time, locomotor task time 21.62.13.11.81.61.51.71.51.6-1.3-1.40.91.21.2
Distance moved, locomotor task time 20.50.51.5-1.0-0.8-0.6-0.9-0.3-0.71.20.2-0.8-0.3-0.5
Vertical activity count, locomotor time 20.71.02.1-1.4-1.4-0.9-1.3-0.9-1.10.90.9-0.4-0.5-0.6
Light reinforcement 10.20.41.70.70.20.40.6-0.00.4-1.31.00.7-0.00.6
Light reinforcement 20.20.30.90.7-0.10.30.60.00.5-0.90.70.60.10.6
Bone: marrow area12.527.442.3-6.5-5.5-5.2-5.9-5.2-5.75.34.6-4.3-4.3-4.6
Bone: maximum diameter6.411.915.2-3.4-3.9-3.6-3.6-3.6-3.23.82.7-3.8-2.9-3.2
Bone: maximum force2.54.58.7-1.4-2.5-2.4-1.8-2.5-1.42.41.3-3.0-1.9-2.1
Bone: maximum moment2.54.58.9-1.4-2.6-2.4-1.8-2.5-1.32.41.2-3.0-1.8-2.0
Mean time between licks in bursts0.71.73.3-0.7-0.8-1.5-0.9-1.5-1.10.91.1-1.5-1.8-1.8
Mean num. licks in bursts0.10.10.30.0-0.1-0.40.0-0.4-0.1-0.30.60.1-0.5-0.3
Cd content in liver4.44.96.82.42.62.32.32.42.0-2.5-1.72.41.71.9
Co content in liver1.51.73.01.61.41.51.21.31.0-1.6-0.71.71.11.1
Cu content in liver0.10.10.4-0.3-0.5-0.3-0.3-0.4-0.30.10.6-0.0-0.3-0.1
Fe content in liver0.50.61.80.20.31.00.20.80.5-0.2-0.90.91.31.1
K content in liver0.20.20.70.30.10.50.20.20.2-0.50.00.80.60.8
Mg content in liver4.64.77.62.02.02.22.22.12.0-2.5-1.32.81.92.5
Mn content in liver2.83.15.91.41.02.01.51.81.8-1.6-1.31.82.22.4
Na content in liver0.20.20.7-0.40.00.3-0.20.4-0.3-0.20.20.80.40.6
Rb content in liver5.36.27.72.32.42.82.42.62.4-2.2-2.42.52.72.7
Se content in liver1.72.02.91.71.61.31.61.41.4-1.6-1.01.50.91.1
Sr content in liver1.81.62.2-0.9-1.4-1.4-1.2-1.4-1.11.31.0-1.5-1.3-1.4
Zn content in liver0.30.30.70.60.50.40.70.60.8-0.3-0.90.30.50.4
Bone: minimum diameter15.227.831.8-5.4-5.6-5.6-5.5-5.6-5.35.04.9-5.0-4.9-5.0
Time in familiar zone, hab. session 10.40.41.1-0.5-0.1-0.6-0.6-0.5-1.00.01.00.1-0.9-0.7
Time in novel zone, hab. session 10.40.41.40.50.20.50.60.51.00.1-1.2-0.40.80.6
Total zone transitions, hab. session 10.10.10.3-0.1-0.2-0.3-0.3-0.5-0.40.10.5-0.3-0.6-0.5
Total locomotion distance, hab. session 10.30.51.2-0.5-1.1-0.6-0.6-0.7-0.30.80.5-1.0-0.4-0.4
Locomotion velocity, hab. session 10.40.61.5-0.7-1.2-0.6-0.8-0.9-0.50.80.8-0.9-0.5-0.5
Time in familiar zone, hab. session 20.50.61.5-1.1-0.1-0.6-0.8-0.6-1.20.20.90.2-0.9-0.8
Time in novel zone, hab. session 20.60.61.81.0-0.10.50.80.61.4-0.0-1.0-0.50.90.8
Total zone transitions, hab. session 20.10.20.60.10.60.50.30.30.0-0.70.10.80.10.3
Total locomotion distance, hab. session 20.30.41.20.40.60.70.80.50.5-1.10.20.90.20.7
Locomotion velocity, hab. session 20.30.41.30.60.60.70.80.50.6-1.10.20.80.20.7
Novel to familiar place preference ratio1.01.01.7-0.7-1.0-1.3-0.9-1.1-0.80.90.8-1.2-1.1-1.1
Novelty place preference0.60.61.1-0.5-0.8-1.0-0.7-0.8-0.60.80.5-1.0-0.7-0.8
Time in novel zone, NPP test0.40.51.0-0.5-0.7-0.9-0.6-0.7-0.50.80.2-1.0-0.5-0.7
Total zone transitions, NPP test0.30.40.90.70.50.80.70.40.6-0.9-0.10.70.50.8
Total locomotion distance, NPP test0.10.10.30.1-0.20.40.20.10.4-0.30.10.20.30.6
Locomotion velocity, NPP test0.10.10.40.4-0.10.30.4-0.10.3-0.60.50.2-0.10.3
Intraocular pressure2.43.55.9-1.1-1.5-2.1-1.5-2.2-1.81.12.2-1.8-2.4-2.3
Delta distance traveled before/after self-admin0.60.61.20.61.10.80.81.00.5-0.8-0.61.10.60.7
Delta ambulatory time before/after self-admin0.20.30.70.50.90.40.60.60.3-0.6-0.20.80.20.4
Parametrial fat weight0.30.82.2-0.5-1.5-0.8-0.8-0.8-0.31.10.5-1.5-0.3-0.5
Pavlov. Cond. lever latency1.82.23.81.71.91.41.81.31.4-1.9-0.91.60.81.0
Pavlov. Cond. magazine entry latency2.02.65.0-2.0-2.2-1.5-1.9-1.6-1.61.71.5-1.3-0.9-0.9
Pavlov. Cond. change in total contacts1.81.93.7-1.7-1.9-1.2-1.7-1.3-1.41.41.3-1.0-0.7-0.6
Pavlov. Cond. index score2.12.74.7-2.0-2.2-1.6-2.0-1.6-1.61.91.4-1.5-1.0-1.0
Pavlov. Cond. latency score1.92.33.9-1.9-2.0-1.5-1.8-1.4-1.61.71.2-1.4-1.0-1.0
Pavlov. Cond. lever contacts2.02.44.0-1.9-2.0-1.4-1.9-1.4-1.62.01.0-1.6-0.8-1.0
Pavlov. Cond. magazine entry number1.01.32.91.51.70.91.41.11.1-1.2-1.20.70.50.4
Pavlov. Cond. intertrial magazine entries0.60.73.0-0.4-0.1-0.6-0.4-0.8-0.9-0.51.70.3-1.3-0.8
Pavlov. Cond. lever-magazine prob. diff.2.63.25.8-2.0-2.4-1.7-2.1-1.8-1.72.11.4-1.8-1.1-1.2
Pavlov. Cond. response bias2.43.06.7-2.1-2.6-1.5-2.1-1.6-1.52.11.3-1.6-0.7-0.7
Pavlov. Cond. lever latency0.20.30.60.80.60.40.70.50.6-0.6-0.40.20.10.2
Pavlov. Cond. magazine entry latency0.91.11.81.31.11.20.81.10.9-0.7-1.31.01.30.9
Pavlov. Cond. change in total contacts0.10.20.9-0.70.10.1-0.40.0-0.6-0.30.41.00.20.3
Pavlov. Cond. index score0.10.10.2-0.4-0.2-0.0-0.5-0.1-0.40.4-0.10.10.30.1
Pavlov. Cond. latency score0.10.10.3-0.4-0.30.0-0.5-0.1-0.30.5-0.3-0.00.40.1
Pavlov. Cond. lever contacts0.10.10.3-0.5-0.4-0.2-0.4-0.3-0.40.30.30.0-0.0-0.0
Pavlov. Cond. magazine entry number2.02.44.1-1.5-1.5-1.7-1.3-1.7-1.51.02.0-1.3-1.9-1.5
Pavlov. Cond. intertrial magazine entries9.614.520.5-3.6-4.0-4.0-3.6-4.3-3.82.94.5-3.1-4.1-3.5
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.2-0.10.1-0.30.0-0.20.3-0.20.20.40.2
Pavlov. Cond. response bias0.00.00.2-0.10.00.2-0.10.1-0.0-0.0-0.10.40.40.3
Time in closed arm before self-admin0.10.10.3-0.30.10.3-0.00.3-0.0-0.2-0.20.60.40.3
Time in closed arm after self-admin0.30.41.20.30.60.50.40.70.6-0.1-1.10.40.80.5
Time in open arm before self-admin0.50.62.20.0-0.3-0.4-0.2-0.20.11.4-1.0-1.5-0.1-0.7
Time in open arm after self-admin0.50.51.2-0.3-0.3-0.6-0.5-0.6-0.80.31.0-0.7-1.1-0.9
Bone: periosteal estimation9.920.826.5-5.0-5.1-4.7-4.9-4.7-4.44.93.7-4.6-3.8-4.0
Bone: periosteal perimeter8.815.219.6-3.7-4.3-4.1-4.1-4.0-3.64.42.8-4.4-3.3-3.8
Bone: post-yield work3.55.16.8-2.2-2.1-2.4-2.3-2.2-2.22.61.4-2.5-2.1-2.4
Progressive ratio test 1 active lever presses2.42.93.9-1.8-1.8-1.8-1.7-1.7-1.71.32.0-1.5-1.8-1.6
Progressive ratio test 1 breakpoint2.53.04.5-1.8-1.8-1.8-1.7-1.7-1.81.22.1-1.4-1.9-1.6
Progressive ratio test 1 inactive lever presses2.03.04.0-2.0-1.8-1.8-1.8-1.7-1.81.32.0-1.1-1.8-1.6
Progressive ratio test 2 active lever presses5.46.38.0-2.4-2.6-2.7-2.4-2.7-2.51.92.8-2.1-2.7-2.5
Progressive ratio test 2 breakpoint6.37.28.8-2.6-2.7-2.9-2.6-2.9-2.82.13.0-2.2-2.9-2.7
Progressive ratio test 2 inactive lever presses1.42.34.9-1.3-1.4-1.8-1.2-1.8-1.40.52.2-0.7-2.0-1.6
Incentive Sensitization - Responses3.65.06.2-2.0-2.2-2.5-2.2-2.5-2.31.92.3-1.9-2.4-2.4
Incentive Sensitization - Breakpoint3.95.16.2-2.1-2.2-2.5-2.3-2.5-2.31.92.3-1.9-2.4-2.4
Sum of active levers in priming session hrs 5-60.90.81.60.61.20.90.81.20.5-1.1-0.41.30.50.7
Progressive ratio0.20.30.7-0.5-0.2-0.5-0.4-0.8-0.60.20.7-0.3-0.6-0.5
Food seeking constrained by brief footshock1.92.36.2-2.5-0.8-1.4-1.7-1.3-2.11.01.7-0.3-1.5-1.3
Seeking ratio, punishment vs. effort0.40.61.7-1.3-0.7-0.7-0.9-0.5-1.00.60.8-0.2-0.7-0.6
Retroperitoneal fat weight0.31.12.3-0.8-1.2-1.2-0.9-1.4-1.00.41.5-0.7-1.1-0.9
Reaction time number correct0.10.10.50.7-0.00.00.30.10.40.0-0.3-0.50.0-0.1
Reaction time mean minus median0.10.20.30.60.20.60.40.50.6-0.4-0.50.30.50.4
Reaction time mean minus median AUC0.82.02.71.61.11.51.51.31.6-1.4-1.31.31.51.4
Reaction time num false alarms3.65.06.1-2.4-2.4-2.3-2.5-2.3-2.42.22.1-1.9-2.1-2.1
Reaction time num false alarms AUC2.84.45.4-2.2-2.3-2.2-2.3-2.1-2.22.02.1-1.7-1.9-1.9
Reaction time trials correct on left0.10.10.50.7-0.00.00.30.10.40.0-0.3-0.50.0-0.1
Reaction time trials on left0.10.10.50.7-0.1-0.00.30.10.40.1-0.2-0.5-0.0-0.2
Reaction time mean1.52.44.01.11.11.81.31.61.6-1.1-1.71.42.01.8
Reaction time mean AUC1.93.15.01.21.42.01.51.91.8-1.3-2.01.62.22.1
Median of all reaction times1.92.74.71.11.21.91.41.71.7-1.1-1.81.52.22.0
Reaction time omissions0.10.10.7-0.1-0.8-0.0-0.1-0.20.30.40.1-0.60.20.1
Reaction time false alarm rate2.63.65.2-2.3-2.0-1.9-2.2-1.9-2.21.81.8-1.3-1.6-1.6
Reaction time premature initiation rate0.60.81.9-0.9-0.8-1.1-0.7-0.9-0.90.51.4-0.4-1.1-0.9
Reaction time premature initiations0.40.71.6-0.6-0.7-1.0-0.5-0.8-0.70.41.3-0.6-1.2-0.9
Std. dev. reaction times0.71.31.81.10.71.31.01.11.3-1.0-1.11.11.41.3
Reaction time trials completed0.10.10.50.7-0.1-0.00.30.10.40.1-0.2-0.5-0.0-0.2
Reaction time trials AUC0.10.10.60.80.10.10.40.20.5-0.1-0.3-0.40.1-0.1
Run reversals in cocaine runway, females1.31.35.0-0.1-1.0-1.1-0.6-1.0-0.41.40.3-2.2-1.2-1.4
Run reversals in cocaine runway, males0.70.72.0-0.3-0.9-0.7-0.7-0.7-0.51.20.2-1.4-0.6-0.9
Latency to leave start box in cocaine runway0.00.00.10.20.10.10.10.30.10.3-0.4-0.30.1-0.0
Latency to leave start box in cocaine runway, F0.60.72.6-0.3-0.6-0.7-0.6-0.5-0.31.5-0.5-1.6-0.3-0.8
Latency to leave start box in cocaine runway, M0.90.92.30.40.91.10.71.20.4-1.1-0.11.50.71.1
Std. dev. time between licks in bursts0.00.10.20.30.3-0.10.3-0.00.1-0.40.10.1-0.3-0.1
Total sessions with >9 infusions0.40.51.1-0.4-0.4-0.8-0.4-0.8-0.60.20.9-0.4-1.0-0.9
Short access day 1 total inactive lever presses2.33.14.1-1.8-2.0-2.0-1.7-1.9-1.51.61.4-1.7-1.7-1.8
Short access day 10 total inactive lever presses0.10.20.50.1-0.5-0.4-0.1-0.7-0.1-0.00.6-0.4-0.6-0.4
Short access day 1 total infusions0.30.40.8-0.5-0.6-0.6-0.5-0.5-0.60.20.9-0.4-0.8-0.7
Short access day 10 total infusions1.72.23.8-1.6-1.5-1.5-1.5-1.6-1.70.81.9-0.7-1.7-1.5
Short access total infusions0.91.21.8-1.2-1.2-1.1-1.1-1.1-1.20.71.3-0.6-1.2-1.0
Short access day 1 locomotion2.53.15.0-1.2-1.7-2.1-1.4-2.0-1.60.92.1-1.4-2.2-2.1
Short access day 10 total locomotion2.64.87.4-2.7-2.1-2.3-2.3-2.1-2.51.72.6-1.3-2.3-2.0
Short access total locomotion3.03.74.6-1.9-1.9-2.1-1.8-2.1-2.01.42.1-1.4-2.2-2.0
One hour access (0.3 mA shock)2.22.52.9-1.6-1.5-1.6-1.7-1.5-1.71.61.3-1.6-1.6-1.7
Compulsive drug intake0.10.20.80.4-0.1-0.00.1-0.10.50.4-0.9-0.40.50.1
One hour access (shock baseline)0.91.42.5-1.3-0.9-1.0-1.2-0.8-1.50.91.6-0.8-1.5-1.2
Social response proportion0.30.31.10.2-0.4-0.7-0.4-0.5-0.50.40.3-0.7-0.8-1.1
Social responses0.10.10.3-0.1-0.3-0.4-0.4-0.2-0.50.10.5-0.0-0.4-0.5
Social time1.01.42.5-1.0-1.1-1.4-1.2-1.3-1.11.10.7-1.2-1.2-1.6
Soleus weight0.82.33.4-1.2-1.3-1.7-1.4-1.5-1.51.71.0-1.8-1.6-1.8
Bone: stiffness0.40.60.9-0.7-0.7-0.9-0.7-0.9-0.70.80.5-0.9-0.8-0.8
Tibialis anterior weight0.51.64.80.2-0.0-1.3-0.5-1.2-1.4-0.42.0-0.1-2.2-1.7
Time to tail flick, vehicle, before self-admin0.30.30.9-0.2-0.9-0.1-0.50.00.10.9-0.6-0.90.4-0.2
Time to tail flick, vehicle, after self-admin0.10.10.5-0.1-0.5-0.4-0.2-0.7-0.10.10.5-0.4-0.2-0.2
Time to tail flick, test, before self-admin0.10.10.4-0.10.50.40.20.40.10.0-0.70.40.40.3
Time to tail flick, test, after self-admin0.10.10.20.00.20.20.1-0.10.1-0.40.10.50.30.4
Delta time to tail flick, vehicle, before/after SA0.40.41.7-0.7-0.3-0.6-0.4-0.8-0.7-0.21.30.0-0.7-0.3
Delta time to tail flick, test, before/after SA0.10.10.40.30.10.40.20.10.2-0.50.20.50.40.6
Tibia length0.10.41.80.2-0.6-0.6-0.3-0.40.01.0-0.2-1.3-0.3-0.5
Ambulatory time before self-admin0.50.72.2-0.8-1.1-0.6-1.0-0.5-0.61.5-0.2-1.2-0.1-0.7
Ambulatory time after self-admin0.10.10.5-0.3-0.4-0.2-0.4-0.1-0.30.7-0.3-0.40.0-0.3
Bone: tissue strength1.01.01.71.31.00.91.11.01.2-0.7-1.30.50.90.8
Total heroin consumption0.30.31.8-1.4-0.4-0.0-0.70.1-0.50.9-0.3-0.00.40.2
Bone: trabecular number0.50.92.5-1.3-1.6-0.8-0.8-0.7-0.31.20.6-1.2-0.2-0.1
Bone: trabecular spacing0.30.41.30.61.20.40.40.4-0.1-0.8-0.21.0-0.1-0.1
Bone: trabecular thickness2.93.67.1-1.5-2.7-2.1-1.7-2.1-1.12.11.5-2.6-1.4-1.5
Bone: trabecular tissue density0.60.92.61.60.30.71.10.51.5-0.7-0.8-0.20.90.8
Water consumed over 24 hours0.10.10.2-0.0-0.3-0.4-0.2-0.3-0.10.30.1-0.4-0.2-0.2
Number of responses in last shaping day1.51.73.7-1.2-1.6-1.1-1.3-1.2-0.91.70.6-1.9-0.9-1.2