LOC134480887

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC134480887 0.17 0.08 4.1e-06 0.03 0.04 0.04 0.04 1.5e-04 2.2e-05 2.6e-05 9.2e-05
2 pVTA gene expression LOC134480887 0.17 0.08 3.1e-06 0.09 0.08 0.07 0.08 2.1e-07 1.1e-06 4.7e-06 6.5e-07
3 NAcc gene expression LOC134480887 0.05 0.03 1.7e-03 0.02 0.01 0.02 0.02 7.2e-04 4.1e-03 8.9e-04 6.2e-04
4 Adipose gene expression LOC134480887 0.11 0.05 4.5e-12 0.09 0.11 0.1 0.1 5.7e-10 2.5e-12 1.1e-11 1.5e-11
5 Brain gene expression LOC134480887 0.35 0.1 0.0e+00 0.23 0.24 0.24 0.24 1.7e-21 3.0e-22 5.1e-22 1.5e-22
6 Eye intron excision ratio chr10_89714132_89715351 0.31 0.15 2.6e-03 0.04 0.18 0.2 0.18 7.3e-02 1.2e-03 6.1e-04 1.1e-03
7 Eye gene expression LOC134480887 0.7 0.14 5.3e-07 0.24 0.14 0.16 0.22 1.5e-04 3.9e-03 2.0e-03 2.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density1.01.98.8-0.60.6-0.0-3.0-1.01.0-1.3
Area under the delay curve0.30.51.01.0-0.90.7-0.40.8-0.40.7
BMI with tail2.06.913.22.4-3.52.91.93.6-0.42.1
BMI without tail1.15.811.12.9-3.22.80.73.31.30.1
Body weight3.013.024.04.5-4.94.6-0.54.71.90.3
Weight adjusted by age0.20.61.20.9-1.01.10.10.8-0.00.6
Bone surface1.83.513.11.1-1.41.8-3.60.71.8-1.2
Bone volume1.52.912.60.7-0.91.3-3.50.21.8-1.3
Breakpoint value in progressive ratio session0.00.00.10.20.0-0.30.00.10.10.3
Number of licking bursts0.41.33.11.8-1.31.20.31.4-0.20.8
Context. condit. distance diff. score0.81.02.9-0.2-0.20.11.50.3-1.21.7
Locomotion velocity, session 10.60.72.60.70.1-0.1-1.6-0.31.1-0.8
Locomotion distance, session 10.30.41.20.40.3-0.0-1.1-0.21.0-0.8
Locomotion velocity, session 21.21.42.3-0.91.5-1.3-1.3-1.50.4-0.9
Locomotion distance, session 20.20.30.6-0.00.6-0.7-0.2-0.50.8-0.6
Locomotion velocity, session 30.40.41.1-0.50.6-0.5-1.0-0.8-0.40.4
Locomotion distance, session 30.30.30.90.1-0.00.1-0.8-0.2-0.80.9
Stereotopy head waving bouts, day 31.31.53.1-1.41.4-1.5-1.1-1.8-0.1-0.5
Stereotopy head waving duration, day 30.60.81.4-0.91.1-1.2-0.2-1.20.2-0.8
Locomotion velocity, session 70.50.51.1-0.60.7-0.7-0.4-0.9-1.10.5
Locomotion distance, session 70.20.20.7-0.40.3-0.50.2-0.4-0.80.3
Stereotopy head waving bouts, day 71.21.42.6-1.51.5-1.2-0.8-1.6-0.1-0.8
Stereotopy head waving duration, day 71.92.44.6-1.72.1-1.9-0.3-2.0-0.2-1.1
Locomotion velocity, session 80.50.61.51.2-0.90.60.60.90.50.2
Locomotion distance, session 80.30.41.0-0.30.7-0.71.0-0.4-0.20.6
Degree of sensitization distance0.50.51.00.7-0.60.51.00.90.5-0.6
Degree of sensitization stereotypy0.91.02.2-1.51.4-1.1-0.1-1.3-0.4-0.5
Conditioned locomotion0.20.20.4-0.40.6-0.60.5-0.40.1-0.3
Cocaine response after cond. corrected0.40.61.6-0.4-0.60.7-0.70.2-1.11.3
Cocaine response after cond. not corrected0.60.82.3-0.8-0.30.4-1.5-0.3-1.11.2
Cocaine response before conditioning0.60.82.4-0.50.7-0.6-1.5-0.90.7-0.9
Saline control response1.21.72.21.5-1.10.61.51.21.5-1.4
Bone: connectivity density1.21.97.8-0.40.40.1-2.8-0.81.3-1.7
Bone: cortical apparent density4.36.811.6-3.23.4-3.4-0.1-3.4-1.6-0.3
Bone: cortical area0.71.25.80.1-1.01.2-2.40.30.4-0.1
Bone: cortical porosity6.57.111.62.4-3.43.4-3.32.42.0-0.2
Bone: cortical porosity6.57.213.12.7-3.63.6-2.72.71.70.4
Bone: cortical thickness2.43.98.9-3.01.9-1.4-1.6-2.3-2.20.9
Bone: cortical thickness2.83.47.2-2.71.9-1.7-1.1-2.3-1.80.6
Bone: cortical tissue density4.16.511.4-3.13.4-3.3-0.1-3.3-1.5-0.4
Condit. Reinf. active minus inactive responses0.70.81.71.1-0.80.8-0.80.71.3-0.7
Condit. Reinf. active-inactive response ratio0.10.10.20.3-0.40.4-0.10.40.4-0.4
Condit. Reinf. active responses0.81.02.71.1-0.60.6-1.10.51.6-0.9
Condit. Reinf. inactive responses0.40.51.40.30.1-0.2-1.2-0.31.1-0.7
Incentive salience index mean0.70.92.20.8-0.50.7-1.50.41.4-0.8
Condit. Reinf. lever presses0.40.62.6-0.00.3-0.1-1.6-0.41.0-0.6
Condit. Reinf. active minus inactive responses1.01.66.20.6-0.70.7-2.50.31.6-0.9
Condit. Reinf. active-inactive response ratio0.81.24.00.9-0.91.0-2.00.71.2-0.4
Condit. Reinf. active responses1.52.25.70.9-0.60.6-2.30.32.4-1.7
Condit. Reinf. inactive responses1.21.85.80.00.7-0.7-0.9-0.72.2-2.4
Condit. Reinf. lever presses0.40.61.7-0.10.2-0.0-1.3-0.21.1-1.1
Condit. Reinf. lever reinforcers received1.21.75.30.6-0.40.4-2.30.12.0-1.4
Conditioned reinforcement - actives0.10.41.21.1-0.20.50.70.70.5-0.3
Conditioned reinforcement - inactives0.41.12.20.9-1.51.5-0.41.40.7-0.2
Conditioned locomotion1.21.84.32.1-1.51.7-0.21.51.0-0.1
Patch foraging indifference point 0 sec0.61.85.70.20.2-0.3-1.1-0.52.3-2.4
Patch foraging indifference point AUC0.30.81.31.1-1.00.80.51.10.6-0.7
Delay disc. indifference point, 0s delay0.20.20.50.10.4-0.6-0.0-0.20.3-0.7
Delay disc. indifference point, 16s delay1.11.63.01.3-1.71.4-0.21.3-1.01.4
Delay disc. indifference point, 2s delay0.80.93.00.60.10.1-1.7-0.11.2-1.1
Delay disc. indifference point, 24s delay1.01.63.31.8-1.81.4-0.31.50.50.3
Delay disc. indifference point, 4s delay0.40.41.00.6-0.80.6-0.70.4-0.41.0
Delay disc. indifference point, 8s delay0.10.20.4-0.10.2-0.4-0.6-0.3-0.70.5
Indifference point function ln k0.30.93.4-1.00.7-0.4-1.8-1.10.4-0.3
Indifference point function log k0.30.93.4-1.00.7-0.4-1.8-1.10.4-0.3
Patch foraging total patch changes 0 sec0.61.75.70.4-0.10.1-1.3-0.22.4-2.2
Patch foraging total patch changes 12 sec1.62.17.80.70.4-0.60.2-0.32.5-2.8
Patch foraging total patch changes 18 sec0.20.61.10.9-1.10.90.10.70.7-0.4
Patch foraging total patch changes 24 sec0.41.44.00.6-0.30.1-1.2-0.21.9-2.0
Patch foraging total patch changes 6 sec0.40.72.10.6-0.40.4-0.60.21.3-1.4
Patch foraging time to switch 0 sec0.00.20.50.4-0.20.10.20.2-0.70.7
Patch foraging water rate 0 sec0.10.51.40.4-0.30.6-0.80.21.2-0.8
Patch foraging water rate 12 sec0.20.82.2-0.6-0.40.6-0.9-0.1-1.41.5
Patch foraging water rate 18 sec0.61.32.2-1.41.2-1.0-1.4-1.50.3-0.7
Patch foraging water rate 24 sec1.21.73.9-2.01.6-1.3-0.2-1.7-0.90.4
Patch foraging water rate 6 sec0.30.52.4-0.50.10.2-1.5-0.30.7-0.4
Seeking ratio, delayed vs. immediate footshock2.13.05.12.2-1.91.71.52.3-0.81.1
Distance traveled before self-admin0.20.31.10.0-0.40.4-0.90.2-0.51.0
Distance traveled after self-admin0.40.72.2-0.50.5-0.31.00.2-1.11.5
Extensor digitorum longus weight1.56.022.01.6-1.30.84.72.1-2.22.4
Bone: elastic displacement1.01.22.3-1.50.9-0.5-0.8-1.0-1.31.3
Bone: elastic work0.40.52.8-0.60.10.3-1.7-0.3-0.20.7
Bone: endosteal estimation4.410.816.84.1-4.03.8-2.23.43.3-1.2
Bone: endosteal perimeter6.616.127.25.0-5.24.9-1.94.53.4-0.8
Epididymis fat weight0.10.71.51.0-1.10.80.21.20.5-0.4
Delta time in closed arm before/after self-admin0.80.72.4-0.6-0.4-0.0-0.3-0.1-1.51.5
Delta time in open arm before/after self-admin1.11.33.70.21.0-1.01.0-0.31.4-1.9
Diff in mean of infusions in LGA sessions0.10.10.3-0.2-0.0-0.30.40.10.6-0.4
Delay discount exponential model param0.50.71.5-1.21.1-0.80.4-1.00.3-0.7
Extinction: sum of active levers before priming0.10.20.70.10.7-0.50.9-0.20.00.3
Active lever presses in extinction session 62.12.14.32.1-1.71.6-0.41.81.2-0.1
Bone: final force0.60.94.1-1.0-0.10.1-2.0-0.60.2-0.9
Bone: final moment0.81.25.5-1.20.00.0-2.4-0.80.3-0.9
Food consumed during 24 hour testing period1.42.84.92.2-2.11.80.41.91.4-1.0
Glucose0.81.24.2-0.60.1-0.20.9-0.2-2.01.7
Heart weight1.42.34.01.2-1.92.00.41.9-0.81.8
Delay discount hyperbolic model param0.50.71.6-1.31.0-0.80.6-0.90.0-0.5
Intermittent access intake day 1-15 change0.10.61.40.6-0.30.61.00.4-0.71.2
Intermittent access intake escalation0.10.61.70.5-0.40.81.00.5-0.71.3
Intermittent access intake escalation 20.30.61.30.6-0.60.80.80.6-0.41.2
Intermitt. access day 1 inactive lever presses0.22.44.12.0-1.61.6-1.31.61.5-1.0
Intermitt. access day 15 inactive lever presses0.52.87.21.1-0.71.1-1.80.62.7-2.5
Intermitt. access escalation Index0.30.92.2-0.2-0.70.21.10.5-1.41.5
Intermittent access day 1 total infusions0.20.71.91.1-0.70.5-0.30.50.9-1.4
Intermittent access day 15 total infusions0.71.83.81.9-1.61.51.11.50.4-0.0
Intermittent access terminal intake (last 3 days)1.52.65.52.3-2.01.80.71.71.2-0.8
Intermittent access total infusions1.82.15.12.3-1.61.30.71.51.1-1.2
Intermittent access day 1 locomotion1.83.36.92.6-2.22.1-0.61.91.5-0.8
Intermittent access day 15 total locomotion0.72.76.52.5-1.71.70.81.81.4-0.7
Intermittent access total locomotion3.54.310.03.2-2.22.2-0.32.12.0-1.2
Intermittent access standard deviation0.10.31.11.1-0.00.40.20.50.7-0.5
Left kidney weight0.10.51.3-0.7-0.20.3-1.1-0.1-0.60.9
Right kidney weight0.10.81.30.1-0.91.0-1.10.5-0.81.1
Cocaine induced anxiety0.51.55.2-0.90.1-0.2-0.2-0.5-2.02.3
Post-drug Anxiety0.70.83.8-0.1-0.70.7-0.30.5-0.82.0
Baseline Anxiety1.01.82.81.5-1.41.4-0.11.71.7-0.7
Tail length0.84.59.01.9-1.11.2-3.00.62.9-2.8
Length with tail1.14.98.12.9-2.12.3-2.01.92.4-1.7
Length without tail0.31.73.21.7-1.71.8-0.11.60.10.6
Times rat made contact with spout0.30.30.70.6-0.80.6-0.10.6-0.00.5
Lifetime Intake1.41.74.52.1-1.31.30.31.31.1-1.1
Liver weight, left1.22.12.91.5-1.71.7-1.71.31.4-0.7
Liver weight, right0.71.12.9-1.20.6-0.5-1.7-1.0-1.20.8
Locomotor activity0.50.82.41.1-0.40.60.00.81.6-0.8
Locomotor testing distance0.40.93.31.0-0.60.7-0.00.81.8-0.9
Locomotor testing rearing0.20.71.80.8-0.60.41.30.81.3-0.2
Locomotion in novel chamber1.72.24.81.6-2.22.0-0.81.40.90.9
Locomotion in novel chamber post-restriction0.30.81.61.0-1.00.5-0.70.81.3-0.8
Fecal boli incidents, locomotor time 10.00.10.3-0.1-0.1-0.10.4-0.0-0.50.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.2-0.20.30.00.3-0.60.4
Time >=10cm from walls, locomotor time 11.31.64.5-1.70.4-0.60.8-0.5-1.52.1
Bouts of movement, locomotor time 10.10.10.2-0.40.3-0.50.0-0.4-0.5-0.3
Total resting periods, locomotor time 10.00.10.2-0.20.1-0.1-0.2-0.2-0.4-0.2
Rest time, locomotor task time 10.50.81.6-1.01.3-1.0-0.6-1.3-0.4-0.0
Distance moved, locomotor task time 10.51.52.61.5-1.51.60.31.60.20.6
Vertical activity count, locomotor time 10.10.91.71.0-1.31.3-0.41.20.30.5
Time >=10cm from walls, locomotor time 20.20.61.90.1-0.90.9-0.50.6-0.11.4
Bouts of movement, locomotor time 20.10.41.3-1.10.6-0.5-0.4-0.8-0.10.0
Total resting periods, locomotor time 20.20.62.0-1.40.8-0.7-0.2-1.0-0.50.3
Rest time, locomotor task time 20.40.71.6-0.80.4-0.60.7-0.5-1.31.1
Distance moved, locomotor task time 20.20.30.50.7-0.40.7-0.30.50.50.1
Vertical activity count, locomotor time 20.30.72.20.40.00.3-1.10.11.5-1.0
Light reinforcement 10.52.16.5-0.01.2-0.9-1.0-1.12.0-2.5
Light reinforcement 20.92.14.0-0.71.3-1.1-1.9-1.31.3-2.0
Bone: marrow area4.310.616.44.0-4.03.8-2.23.33.3-1.3
Bone: maximum diameter1.83.76.01.8-2.32.3-2.41.61.7-0.7
Bone: maximum force0.61.23.90.3-1.31.4-2.00.60.6-0.7
Bone: maximum moment0.71.35.50.1-1.11.2-2.30.40.6-0.7
Mean time between licks in bursts0.42.53.91.7-1.91.90.92.0-0.91.2
Mean num. licks in bursts0.20.51.4-1.20.7-0.7-0.3-0.90.1-0.4
Cd content in liver1.92.15.1-1.21.4-1.72.3-1.0-1.40.9
Co content in liver0.30.31.30.10.3-0.51.10.2-0.10.7
Cu content in liver0.30.40.91.0-0.50.5-0.80.50.7-0.3
Fe content in liver0.80.91.7-1.11.2-1.3-0.5-1.3-0.2-0.6
K content in liver1.21.21.8-1.01.3-1.1-1.2-1.30.4-1.1
Mg content in liver3.63.97.4-2.22.7-2.6-0.3-2.6-0.2-1.3
Mn content in liver5.36.09.7-2.63.1-2.6-2.0-3.10.6-2.2
Na content in liver0.40.40.8-0.10.7-0.6-0.4-0.50.9-0.9
Rb content in liver1.92.24.2-1.72.0-2.00.4-1.8-0.5-0.8
Se content in liver0.81.02.1-0.70.9-0.91.2-0.6-1.40.9
Sr content in liver0.80.71.40.6-0.91.0-0.60.6-0.71.2
Zn content in liver0.40.50.9-0.90.5-0.60.2-0.6-0.91.0
Bone: minimum diameter5.811.217.94.0-4.24.2-2.73.52.6-0.6
Time in familiar zone, hab. session 10.60.71.71.2-0.80.51.30.90.10.2
Time in novel zone, hab. session 10.70.82.2-1.50.8-0.4-1.1-0.9-0.50.1
Total zone transitions, hab. session 10.30.50.90.9-0.50.50.70.7-0.40.8
Total locomotion distance, hab. session 10.60.82.40.8-0.50.8-1.50.31.1-0.7
Locomotion velocity, hab. session 10.91.32.51.3-0.70.9-1.50.61.6-1.1
Time in familiar zone, hab. session 20.70.82.71.0-0.80.41.71.00.3-0.1
Time in novel zone, hab. session 21.71.94.8-1.81.3-0.7-2.2-1.6-0.50.1
Total zone transitions, hab. session 20.20.31.20.50.1-0.21.10.2-0.30.6
Total locomotion distance, hab. session 20.20.20.60.60.2-0.30.1-0.10.6-0.7
Locomotion velocity, hab. session 20.10.20.50.70.1-0.30.20.00.6-0.6
Novel to familiar place preference ratio0.30.40.90.4-0.80.9-0.60.70.50.2
Novelty place preference0.20.20.50.2-0.60.7-0.60.40.40.3
Time in novel zone, NPP test0.10.20.5-0.2-0.40.6-0.70.20.30.3
Total zone transitions, NPP test0.10.20.50.00.6-0.7-0.0-0.60.3-0.3
Total locomotion distance, NPP test0.40.51.80.10.3-0.2-1.3-0.51.0-0.7
Locomotion velocity, NPP test0.20.30.90.7-0.10.1-0.80.01.0-0.5
Intraocular pressure1.01.63.31.4-1.81.40.61.70.00.5
Delta distance traveled before/after self-admin0.40.51.9-0.60.7-0.71.4-0.0-0.40.1
Delta ambulatory time before/after self-admin0.20.31.6-0.20.4-0.41.30.3-0.30.1
Parametrial fat weight0.40.84.70.0-0.10.0-2.2-0.21.0-0.3
Pavlov. Cond. lever latency1.41.83.8-1.41.4-1.71.9-1.1-1.0-0.1
Pavlov. Cond. magazine entry latency1.62.06.40.10.00.3-2.5-0.42.1-1.8
Pavlov. Cond. change in total contacts1.71.84.60.9-0.50.7-2.10.32.1-1.4
Pavlov. Cond. index score1.21.55.20.5-0.50.9-2.30.31.7-1.0
Pavlov. Cond. latency score1.01.23.70.7-0.71.0-1.90.51.5-0.6
Pavlov. Cond. lever contacts1.41.73.61.3-1.21.5-1.91.01.20.1
Pavlov. Cond. magazine entry number1.82.35.50.5-0.70.52.41.0-2.12.1
Pavlov. Cond. intertrial magazine entries1.21.43.41.9-1.10.90.91.41.2-0.3
Pavlov. Cond. lever-magazine prob. diff.1.51.86.80.5-0.51.0-2.60.31.8-1.1
Pavlov. Cond. response bias2.32.912.40.1-0.00.4-3.5-0.52.2-1.6
Pavlov. Cond. lever latency0.30.51.90.3-0.30.10.60.3-0.81.4
Pavlov. Cond. magazine entry latency0.40.51.0-0.70.6-0.50.9-0.4-1.00.8
Pavlov. Cond. change in total contacts0.20.41.10.40.2-0.30.50.11.0-1.0
Pavlov. Cond. index score0.00.00.2-0.20.2-0.1-0.0-0.10.2-0.4
Pavlov. Cond. latency score0.00.00.1-0.20.10.1-0.2-0.10.1-0.3
Pavlov. Cond. lever contacts0.30.51.7-0.40.5-0.3-0.5-0.50.8-1.3
Pavlov. Cond. magazine entry number1.11.42.41.5-1.21.1-0.81.01.5-1.1
Pavlov. Cond. intertrial magazine entries3.16.710.73.0-2.52.5-2.42.13.3-2.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.20.2-0.1-0.0-0.20.0-0.4
Pavlov. Cond. response bias0.20.30.5-0.70.7-0.7-0.1-0.70.2-0.6
Time in closed arm before self-admin0.30.61.1-0.70.9-1.00.4-0.7-0.0-1.1
Time in closed arm after self-admin1.01.14.2-1.20.3-0.80.7-0.5-2.10.7
Time in open arm before self-admin2.02.48.70.0-1.31.40.10.9-2.03.0
Time in open arm after self-admin1.01.12.21.4-1.01.10.61.51.00.4
Bone: periosteal estimation2.96.99.92.7-3.13.1-3.12.22.5-1.1
Bone: periosteal perimeter3.16.111.52.6-3.43.3-2.32.61.20.2
Bone: post-yield work2.64.59.22.3-2.83.0-0.42.70.11.2
Progressive ratio test 1 active lever presses0.61.11.61.3-0.91.0-0.70.91.2-1.1
Progressive ratio test 1 breakpoint0.71.21.91.4-0.91.0-0.80.91.4-1.2
Progressive ratio test 1 inactive lever presses0.82.04.21.5-1.31.3-1.01.02.0-1.3
Progressive ratio test 2 active lever presses1.52.24.02.0-1.51.6-0.81.51.5-1.1
Progressive ratio test 2 breakpoint1.82.34.22.1-1.61.7-0.71.61.4-1.0
Progressive ratio test 2 inactive lever presses0.92.95.42.3-1.51.6-0.51.62.0-1.7
Incentive Sensitization - Responses0.82.13.71.9-1.71.9-0.41.61.4-0.4
Incentive Sensitization - Breakpoint0.92.13.71.9-1.71.9-0.31.61.3-0.4
Sum of active levers in priming session hrs 5-61.11.02.1-0.81.1-1.11.4-0.7-0.80.9
Progressive ratio0.10.20.50.7-0.10.20.40.20.5-0.4
Food seeking constrained by brief footshock1.21.52.61.2-0.90.61.31.21.4-1.6
Seeking ratio, punishment vs. effort0.10.30.60.3-0.60.30.20.70.6-0.8
Retroperitoneal fat weight0.20.71.80.8-0.60.1-0.90.41.3-1.2
Reaction time number correct0.00.20.70.2-0.10.5-0.30.1-0.40.8
Reaction time mean minus median0.00.10.10.1-0.30.1-0.40.30.20.2
Reaction time mean minus median AUC0.10.61.3-1.10.9-1.0-0.5-0.9-0.30.1
Reaction time num false alarms1.01.73.31.5-1.61.8-0.81.61.0-0.2
Reaction time num false alarms AUC0.81.82.71.4-1.41.6-1.11.41.3-0.7
Reaction time trials correct on left0.00.20.70.2-0.10.5-0.30.1-0.40.8
Reaction time trials on left0.10.20.60.2-0.10.5-0.40.1-0.30.8
Reaction time mean0.40.81.3-1.11.1-1.0-0.7-1.00.3-0.5
Reaction time mean AUC0.51.22.5-1.41.6-1.3-0.6-1.30.2-0.5
Median of all reaction times0.61.01.7-1.21.3-1.1-0.8-1.10.4-0.7
Reaction time omissions1.01.65.3-0.30.3-0.1-2.3-0.51.8-1.5
Reaction time false alarm rate0.91.21.71.1-1.21.2-0.81.11.3-0.9
Reaction time premature initiation rate0.40.71.41.2-1.00.8-0.40.90.9-0.3
Reaction time premature initiations0.20.71.61.3-0.91.0-0.40.90.90.0
Std. dev. reaction times0.20.81.2-1.11.0-1.0-0.8-1.00.3-0.6
Reaction time trials completed0.10.20.60.2-0.10.5-0.40.1-0.30.8
Reaction time trials AUC0.00.10.50.3-0.10.5-0.20.1-0.30.7
Run reversals in cocaine runway, females2.02.34.81.1-2.21.8-0.51.4-1.01.8
Run reversals in cocaine runway, males0.91.01.80.7-1.41.3-0.50.9-0.31.4
Latency to leave start box in cocaine runway0.00.00.1-0.2-0.2-0.00.00.3-0.10.3
Latency to leave start box in cocaine runway, F0.70.82.4-0.0-1.00.9-0.20.9-0.91.6
Latency to leave start box in cocaine runway, M0.90.92.0-0.40.8-1.30.4-0.81.1-1.4
Std. dev. time between licks in bursts0.20.40.91.0-0.50.60.70.8-0.00.4
Total sessions with >9 infusions0.50.71.71.3-0.71.00.61.0-0.0-0.1
Short access day 1 total inactive lever presses0.71.43.21.2-1.71.8-1.11.10.30.5
Short access day 10 total inactive lever presses0.11.01.71.2-0.71.2-1.20.71.3-0.5
Short access day 1 total infusions0.10.30.60.7-0.20.3-0.40.10.7-0.8
Short access day 10 total infusions0.71.22.61.6-1.00.9-0.20.91.2-1.2
Short access total infusions0.50.71.51.2-0.60.8-0.40.51.0-0.8
Short access day 1 locomotion0.81.32.71.5-1.31.6-0.41.30.5-0.1
Short access day 10 total locomotion1.14.511.13.3-2.22.3-0.32.41.9-0.9
Short access total locomotion2.53.98.62.9-2.32.4-0.32.41.2-0.2
One hour access (0.3 mA shock)0.30.41.01.0-0.60.90.00.7-0.00.3
Compulsive drug intake0.40.51.4-1.00.2-0.1-0.6-0.3-1.21.0
One hour access (shock baseline)0.71.95.32.3-1.41.50.41.51.1-0.4
Social response proportion1.82.23.81.6-1.91.90.82.0-0.21.1
Social responses0.40.50.90.9-0.71.00.30.70.9-0.3
Social time1.62.45.21.5-2.02.30.42.0-0.11.1
Soleus weight0.51.52.81.3-1.71.50.41.5-0.51.2
Bone: stiffness0.10.20.60.2-0.60.4-0.20.40.5-0.8
Tibialis anterior weight0.82.75.02.0-1.81.42.22.10.10.6
Time to tail flick, vehicle, before self-admin0.91.12.4-1.40.5-0.7-1.5-1.2-0.80.7
Time to tail flick, vehicle, after self-admin0.20.41.10.6-0.60.4-1.10.60.8-0.1
Time to tail flick, test, before self-admin0.40.51.7-0.20.3-0.11.00.1-1.30.6
Time to tail flick, test, after self-admin0.30.41.00.8-0.40.2-0.20.31.0-0.8
Delta time to tail flick, vehicle, before/after SA1.11.22.81.4-0.60.9-0.21.01.7-1.0
Delta time to tail flick, test, before/after SA1.11.35.11.2-0.50.3-0.70.12.3-1.3
Tibia length0.10.30.70.1-0.60.3-0.60.2-0.70.9
Ambulatory time before self-admin0.10.41.3-0.1-0.30.3-0.80.1-0.71.2
Ambulatory time after self-admin0.20.42.0-0.30.2-0.20.20.1-0.81.4
Bone: tissue strength0.70.71.8-1.31.0-0.80.5-0.7-0.90.3
Total heroin consumption0.10.10.60.3-0.1-0.1-0.4-0.10.8-0.2
Bone: trabecular number1.22.210.0-0.10.20.3-3.2-0.61.6-1.6
Bone: trabecular spacing0.91.47.00.5-0.70.32.71.0-0.40.7
Bone: trabecular thickness1.62.29.41.1-1.01.4-3.10.51.0-0.6
Bone: trabecular tissue density0.50.91.9-1.11.0-0.9-1.4-1.2-0.2-0.3
Water consumed over 24 hours0.00.10.20.3-0.40.2-0.40.0-0.30.3
Number of responses in last shaping day1.62.13.61.7-1.61.9-1.51.50.60.4