Hub : Genes

LOC134480858

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC134480858 0.03 0.03 3.0e-03 0.03 0.02 0.03 0.03 1.4e-03 1.1e-02 2.5e-03 3.9e-03
2 BLA gene expression LOC134480858 0.12 0.09 7.2e-05 0.1 0.08 0.07 0.09 7.8e-06 4.4e-05 1.1e-04 2.8e-05
3 PL gene expression LOC134480858 0.03 0.02 1.9e-03 0.03 0.02 0.02 0.03 2.2e-04 2.0e-03 1.2e-03 7.3e-04
4 Adipose gene expression LOC134480858 0.06 0.04 9.5e-11 0.08 0.07 0.08 0.07 1.8e-09 3.3e-08 4.6e-09 1.8e-08
5 Liver gene expression LOC134480858 0.05 0.03 1.4e-08 0.07 0.06 0.06 0.07 1.2e-08 9.4e-08 9.9e-08 7.9e-08
6 NAcc gene expression LOC134480858 0.12 0.08 0.0e+00 0.11 0.13 0.13 0.13 1.3e-16 1.1e-19 1.2e-19 2.5e-19
7 Brain gene expression LOC134480858 0.03 0.03 9.9e-04 0.04 0.03 0.03 0.03 1.3e-04 7.9e-04 9.6e-04 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density1.12.03.21.81.31.31.41.4-1.21.6
Area under the delay curve0.10.21.0-0.0-1.0-0.1-0.1-0.10.2-0.3
BMI with tail18.464.276.88.88.88.07.87.8-7.47.4
BMI without tail0.94.76.42.52.32.22.12.1-1.91.9
Body weight1.14.67.02.62.01.92.12.1-2.41.8
Weight adjusted by age0.10.20.5-0.5-0.7-0.5-0.1-0.10.4-0.2
Bone surface0.51.01.81.10.80.71.01.0-0.91.3
Bone volume1.02.03.01.61.31.11.31.3-1.41.7
Breakpoint value in progressive ratio session1.22.13.2-1.8-1.5-1.5-1.2-1.21.5-1.3
Number of licking bursts0.51.62.0-1.0-0.8-1.4-1.3-1.31.4-1.3
Context. condit. distance diff. score1.11.31.71.01.01.01.31.3-1.01.3
Locomotion velocity, session 10.10.10.2-0.10.0-0.3-0.4-0.40.4-0.2
Locomotion distance, session 14.76.07.0-2.3-2.5-2.6-2.4-2.42.5-2.2
Locomotion velocity, session 20.81.02.1-1.2-1.4-1.0-0.9-0.90.8-0.6
Locomotion distance, session 26.79.510.2-3.0-3.1-3.0-3.2-3.23.1-3.0
Locomotion velocity, session 30.80.91.50.60.21.01.11.1-1.11.2
Locomotion distance, session 31.01.22.6-1.1-1.6-0.9-1.0-1.01.0-0.8
Stereotopy head waving bouts, day 35.26.27.62.22.62.42.82.8-2.42.4
Stereotopy head waving duration, day 33.84.75.62.02.41.92.32.3-2.12.2
Locomotion velocity, session 71.31.41.7-1.0-1.2-1.3-1.3-1.31.0-1.1
Locomotion distance, session 76.68.59.7-2.6-2.8-3.1-3.1-3.12.8-2.8
Stereotopy head waving bouts, day 70.50.50.80.60.60.80.80.8-0.60.9
Stereotopy head waving duration, day 70.50.60.80.60.60.90.80.8-0.80.8
Locomotion velocity, session 81.01.22.10.60.51.11.31.3-0.91.5
Locomotion distance, session 80.50.71.2-0.9-1.1-0.9-0.7-0.71.0-0.6
Degree of sensitization distance0.50.50.8-0.4-0.1-0.9-0.9-0.90.5-0.9
Degree of sensitization stereotypy0.10.10.3-0.4-0.4-0.2-0.4-0.40.5-0.2
Conditioned locomotion1.11.31.91.41.41.01.01.0-1.20.9
Cocaine response after cond. corrected3.65.47.32.62.72.52.22.2-2.11.9
Cocaine response after cond. not corrected2.13.04.12.02.01.91.61.6-1.61.3
Cocaine response before conditioning2.22.63.6-1.8-1.9-1.5-1.5-1.51.5-1.5
Saline control response0.40.50.9-0.10.1-0.8-0.8-0.80.8-0.9
Bone: connectivity density0.40.61.01.00.30.60.80.8-0.51.0
Bone: cortical apparent density3.45.47.8-2.5-2.8-2.4-2.1-2.12.1-2.1
Bone: cortical area0.40.71.31.10.80.70.70.7-0.70.9
Bone: cortical porosity0.20.20.40.60.60.40.00.0-0.40.5
Bone: cortical porosity0.30.30.70.80.80.5-0.0-0.0-0.50.5
Bone: cortical thickness0.10.10.30.50.20.40.30.3-0.40.5
Bone: cortical thickness0.30.41.5-0.8-1.2-0.5-0.2-0.20.70.1
Bone: cortical tissue density3.96.28.6-2.7-2.9-2.6-2.3-2.32.3-2.2
Condit. Reinf. active minus inactive responses0.91.01.7-1.3-0.7-1.3-0.9-0.91.1-0.7
Condit. Reinf. active-inactive response ratio0.20.20.5-0.10.40.20.50.5-0.10.7
Condit. Reinf. active responses1.11.41.9-1.4-1.0-1.3-1.1-1.11.2-1.1
Condit. Reinf. inactive responses1.41.82.9-0.9-1.2-1.2-1.5-1.51.3-1.7
Incentive salience index mean1.82.33.2-1.8-1.2-1.7-1.4-1.41.7-1.3
Condit. Reinf. lever presses2.63.94.5-1.9-1.7-2.0-2.0-2.02.1-2.0
Condit. Reinf. active minus inactive responses0.30.50.9-0.0-0.2-0.7-0.9-0.90.8-0.9
Condit. Reinf. active-inactive response ratio0.40.71.3-0.0-0.0-0.6-0.9-0.91.1-1.2
Condit. Reinf. active responses0.20.30.40.1-0.2-0.6-0.6-0.60.6-0.6
Condit. Reinf. inactive responses0.00.00.10.1-0.2-0.10.10.1-0.20.3
Condit. Reinf. lever presses0.20.30.8-0.4-0.9-0.5-0.4-0.40.4-0.3
Condit. Reinf. lever reinforcers received0.30.40.60.0-0.4-0.7-0.7-0.70.7-0.7
Conditioned reinforcement - actives0.21.01.7-0.5-0.6-1.3-1.0-1.01.1-1.0
Conditioned reinforcement - inactives0.10.30.50.40.3-0.5-0.6-0.60.3-0.7
Conditioned locomotion0.10.20.60.80.70.10.10.1-0.10.0
Patch foraging indifference point 0 sec0.72.12.51.20.91.51.61.6-1.51.6
Patch foraging indifference point AUC0.00.00.0-0.2-0.0-0.2-0.2-0.20.10.0
Delay disc. indifference point, 0s delay0.30.30.7-0.1-0.6-0.6-0.6-0.60.4-0.9
Delay disc. indifference point, 16s delay1.01.41.91.10.21.41.41.4-1.21.1
Delay disc. indifference point, 2s delay0.30.30.5-0.1-0.7-0.7-0.7-0.70.3-0.6
Delay disc. indifference point, 24s delay0.20.40.8-0.6-0.9-0.4-0.4-0.40.6-0.8
Delay disc. indifference point, 4s delay1.41.53.7-1.1-1.9-1.2-1.0-1.01.0-1.1
Delay disc. indifference point, 8s delay0.10.10.6-0.1-0.80.0-0.2-0.20.2-0.5
Indifference point function ln k0.00.10.3-0.3-0.5-0.2-0.2-0.20.2-0.6
Indifference point function log k0.00.10.3-0.3-0.5-0.2-0.2-0.20.2-0.6
Patch foraging total patch changes 0 sec0.72.12.51.31.01.51.61.6-1.61.5
Patch foraging total patch changes 12 sec0.00.00.00.1-0.0-0.2-0.1-0.10.00.0
Patch foraging total patch changes 18 sec1.02.32.51.41.41.61.51.5-1.61.6
Patch foraging total patch changes 24 sec0.30.91.40.80.91.01.01.0-0.91.2
Patch foraging total patch changes 6 sec0.71.21.81.00.81.21.11.1-1.11.3
Patch foraging time to switch 0 sec0.00.10.3-0.3-0.3-0.4-0.3-0.30.6-0.1
Patch foraging water rate 0 sec0.83.23.81.61.51.81.91.9-1.91.8
Patch foraging water rate 12 sec0.20.91.30.70.61.01.01.0-1.01.1
Patch foraging water rate 18 sec0.00.00.1-0.30.0-0.1-0.2-0.2-0.1-0.3
Patch foraging water rate 24 sec1.11.62.31.01.51.11.31.3-1.31.2
Patch foraging water rate 6 sec0.10.10.30.2-0.20.30.60.6-0.10.3
Seeking ratio, delayed vs. immediate footshock2.02.84.12.01.81.51.41.4-1.71.8
Distance traveled before self-admin0.71.62.7-0.9-0.9-1.3-1.3-1.31.6-1.3
Distance traveled after self-admin0.10.20.60.4-0.20.30.50.50.10.8
Extensor digitorum longus weight1.14.55.82.01.71.92.42.4-2.22.1
Bone: elastic displacement0.10.10.30.10.10.10.60.6-0.20.3
Bone: elastic work0.00.00.10.2-0.1-0.20.20.20.00.2
Bone: endosteal estimation0.00.10.30.50.40.10.30.3-0.30.2
Bone: endosteal perimeter0.30.60.80.90.90.60.80.8-0.70.7
Epididymis fat weight0.10.41.41.01.20.3-0.0-0.0-0.2-0.3
Delta time in closed arm before/after self-admin0.30.30.80.60.90.30.40.4-0.70.3
Delta time in open arm before/after self-admin0.70.81.8-1.2-1.3-0.7-0.7-0.70.9-0.7
Diff in mean of infusions in LGA sessions0.81.52.4-1.3-0.7-1.5-1.2-1.21.4-1.1
Delay discount exponential model param0.20.21.30.21.10.20.20.2-0.30.4
Extinction: sum of active levers before priming0.81.22.0-0.9-0.8-1.4-1.1-1.11.1-1.3
Active lever presses in extinction session 60.50.51.10.30.30.71.01.0-0.40.9
Bone: final force0.10.20.70.80.80.2-0.1-0.1-0.00.1
Bone: final moment0.20.31.01.00.80.40.10.1-0.20.3
Food consumed during 24 hour testing period1.32.63.1-1.8-1.7-1.5-1.6-1.61.5-1.5
Glucose1.82.93.91.52.01.51.61.6-1.91.8
Heart weight0.81.43.71.51.90.80.70.7-1.01.0
Delay discount hyperbolic model param0.20.21.10.21.10.20.30.3-0.30.4
Intermittent access intake day 1-15 change0.00.10.50.0-0.7-0.1-0.2-0.20.30.0
Intermittent access intake escalation0.00.10.40.1-0.6-0.1-0.1-0.10.30.1
Intermittent access intake escalation 20.10.20.50.60.20.50.50.5-0.20.7
Intermitt. access day 1 inactive lever presses0.00.00.00.00.1-0.10.10.10.10.0
Intermitt. access day 15 inactive lever presses0.42.22.81.41.51.71.51.5-1.71.3
Intermitt. access escalation Index0.10.30.7-0.9-0.7-0.5-0.4-0.40.6-0.4
Intermittent access day 1 total infusions0.00.00.1-0.00.2-0.3-0.2-0.20.0-0.2
Intermittent access day 15 total infusions0.00.10.20.0-0.3-0.4-0.4-0.40.4-0.3
Intermittent access terminal intake (last 3 days)0.00.00.10.40.2-0.2-0.1-0.10.1-0.0
Intermittent access total infusions0.00.00.20.40.3-0.2-0.1-0.1-0.1-0.1
Intermittent access day 1 locomotion0.30.50.9-0.5-0.2-0.7-0.8-0.80.5-1.0
Intermittent access day 15 total locomotion0.10.60.9-0.1-0.4-0.8-0.9-0.90.6-1.0
Intermittent access total locomotion0.20.30.50.0-0.1-0.6-0.6-0.60.4-0.7
Intermittent access standard deviation0.10.61.11.00.80.80.70.7-0.70.8
Left kidney weight0.00.10.20.5-0.3-0.30.30.3-0.40.5
Right kidney weight0.21.42.21.51.00.81.11.1-1.31.3
Cocaine induced anxiety0.00.10.30.50.6-0.10.20.2-0.10.2
Post-drug Anxiety0.60.71.3-0.7-0.4-1.1-0.9-0.90.9-0.9
Baseline Anxiety0.81.32.4-1.5-1.2-0.9-1.1-1.11.0-1.1
Tail length12.667.993.7-8.8-9.7-8.3-7.8-7.87.5-7.6
Length with tail6.729.645.0-5.6-6.7-5.6-5.2-5.24.5-5.0
Length without tail0.10.51.31.20.30.40.60.6-1.10.5
Times rat made contact with spout1.21.42.4-1.1-0.5-0.9-1.5-1.50.9-1.4
Lifetime Intake0.00.00.10.20.20.00.10.1-0.10.0
Liver weight, left0.00.10.30.10.50.1-0.0-0.00.00.2
Liver weight, right0.00.10.2-0.3-0.4-0.4-0.0-0.00.10.2
Locomotor activity0.10.10.30.60.20.50.20.20.1-0.2
Locomotor testing distance0.30.61.71.30.91.10.60.6-0.30.2
Locomotor testing rearing0.00.10.40.7-0.20.20.20.20.30.1
Locomotion in novel chamber0.20.20.7-0.2-0.1-0.9-0.4-0.40.6-0.1
Locomotion in novel chamber post-restriction0.41.24.21.72.10.30.20.2-0.90.5
Fecal boli incidents, locomotor time 12.15.47.41.72.12.72.32.3-2.32.7
Change in fecal boli incidents, locomotor task2.02.13.1-1.3-1.3-1.8-1.4-1.41.5-1.5
Time >=10cm from walls, locomotor time 10.20.20.50.0-0.2-0.5-0.5-0.50.7-0.4
Bouts of movement, locomotor time 10.30.30.50.60.40.50.60.6-0.70.6
Total resting periods, locomotor time 10.70.81.11.00.80.80.90.9-1.11.0
Rest time, locomotor task time 10.10.20.60.40.80.50.10.1-0.50.2
Distance moved, locomotor task time 10.72.12.7-1.5-1.3-1.5-1.3-1.31.6-1.5
Vertical activity count, locomotor time 10.10.50.8-0.7-0.5-0.8-0.5-0.50.9-0.8
Time >=10cm from walls, locomotor time 20.20.50.6-0.7-0.6-0.7-0.7-0.70.8-0.8
Bouts of movement, locomotor time 20.00.10.30.3-0.1-0.5-0.1-0.10.1-0.1
Total resting periods, locomotor time 20.00.10.40.4-0.1-0.6-0.2-0.20.2-0.2
Rest time, locomotor task time 20.40.71.1-1.0-0.4-0.6-1.1-1.10.6-0.9
Distance moved, locomotor task time 20.10.10.5-0.4-0.7-0.30.10.10.1-0.1
Vertical activity count, locomotor time 20.00.10.1-0.1-0.4-0.30.10.10.2-0.2
Light reinforcement 10.00.00.20.30.00.40.20.20.1-0.0
Light reinforcement 20.20.50.8-0.5-0.4-0.5-0.9-0.90.8-0.7
Bone: marrow area0.00.10.20.40.3-0.00.30.3-0.20.1
Bone: maximum diameter0.40.81.11.11.00.80.90.9-0.70.8
Bone: maximum force0.40.91.81.31.20.70.70.7-0.81.0
Bone: maximum moment0.71.32.21.51.30.90.90.9-1.01.2
Mean time between licks in bursts0.20.92.11.41.40.80.40.4-1.10.3
Mean num. licks in bursts0.00.10.30.10.30.5-0.0-0.0-0.60.1
Cd content in liver0.20.30.60.00.2-0.3-0.8-0.80.5-0.5
Co content in liver0.00.00.00.0-0.00.1-0.2-0.20.1-0.1
Cu content in liver9.411.113.6-3.0-2.8-3.7-3.6-3.63.5-3.0
Fe content in liver1.21.52.8-0.7-0.7-1.7-1.4-1.41.3-1.1
K content in liver1.41.32.3-0.9-0.5-1.5-1.4-1.40.8-1.1
Mg content in liver6.57.210.0-2.3-2.1-3.2-3.0-3.02.5-2.6
Mn content in liver4.55.17.5-2.5-2.7-2.1-2.1-2.12.1-1.9
Na content in liver0.20.20.7-0.30.1-0.8-0.6-0.60.4-0.4
Rb content in liver0.80.91.7-0.5-0.8-1.1-1.1-1.11.3-0.7
Se content in liver0.10.10.30.40.60.30.10.1-0.2-0.1
Sr content in liver1.00.92.2-1.3-1.5-0.7-0.7-0.70.6-0.7
Zn content in liver0.40.51.0-0.3-0.0-1.0-0.8-0.80.7-0.5
Bone: minimum diameter0.00.10.30.60.3-0.00.10.1-0.30.1
Time in familiar zone, hab. session 10.20.30.5-0.1-0.2-0.4-0.6-0.60.7-0.7
Time in novel zone, hab. session 12.73.14.31.31.31.71.91.9-1.82.1
Total zone transitions, hab. session 17.09.810.5-3.1-3.0-3.0-3.2-3.23.2-3.1
Total locomotion distance, hab. session 14.25.96.8-2.2-2.3-2.4-2.6-2.62.6-2.4
Locomotion velocity, hab. session 15.68.09.3-2.5-2.5-2.8-3.1-3.12.9-2.9
Time in familiar zone, hab. session 21.31.42.21.11.21.51.21.2-1.11.2
Time in novel zone, hab. session 20.20.20.5-0.3-0.5-0.7-0.4-0.40.5-0.4
Total zone transitions, hab. session 24.96.26.9-2.3-2.3-2.5-2.6-2.62.6-2.5
Total locomotion distance, hab. session 21.31.72.1-1.0-1.0-1.4-1.5-1.51.3-1.3
Locomotion velocity, hab. session 21.41.92.4-1.2-1.1-1.5-1.5-1.51.4-1.4
Novel to familiar place preference ratio0.20.20.4-0.4-0.5-0.6-0.3-0.30.7-0.3
Novelty place preference0.10.10.3-0.3-0.5-0.5-0.2-0.20.6-0.2
Time in novel zone, NPP test0.00.10.2-0.2-0.3-0.30.10.10.40.0
Total zone transitions, NPP test7.010.412.2-2.9-3.1-3.0-3.5-3.53.2-3.3
Total locomotion distance, NPP test2.73.84.8-1.5-1.8-2.0-2.2-2.22.0-2.0
Locomotion velocity, NPP test3.34.85.9-1.8-2.0-2.2-2.4-2.42.1-2.2
Intraocular pressure0.91.51.8-1.1-1.2-1.3-1.1-1.11.2-1.3
Delta distance traveled before/after self-admin1.41.62.61.20.51.21.31.3-1.31.6
Delta ambulatory time before/after self-admin1.01.72.31.20.91.31.31.3-1.31.5
Parametrial fat weight0.10.20.70.80.40.40.10.1-0.50.2
Pavlov. Cond. lever latency1.62.02.61.31.31.31.51.5-1.61.5
Pavlov. Cond. magazine entry latency0.10.10.3-0.3-0.3-0.2-0.3-0.30.6-0.3
Pavlov. Cond. change in total contacts3.84.15.1-2.0-1.9-2.0-2.0-2.02.3-2.0
Pavlov. Cond. index score1.01.22.0-1.0-1.0-1.0-1.1-1.11.4-1.1
Pavlov. Cond. latency score1.01.21.9-1.1-1.0-1.0-1.1-1.11.4-1.1
Pavlov. Cond. lever contacts3.34.04.6-1.9-1.7-1.9-2.1-2.12.1-2.1
Pavlov. Cond. magazine entry number0.70.91.40.80.80.90.90.9-1.21.0
Pavlov. Cond. intertrial magazine entries1.61.92.6-1.0-0.9-1.5-1.6-1.61.2-1.6
Pavlov. Cond. lever-magazine prob. diff.1.01.21.9-1.0-1.0-1.0-1.1-1.11.4-1.1
Pavlov. Cond. response bias1.21.52.1-1.0-1.1-1.1-1.2-1.21.4-1.3
Pavlov. Cond. lever latency1.82.53.3-1.3-1.1-1.5-1.7-1.71.7-1.8
Pavlov. Cond. magazine entry latency0.10.20.7-0.8-0.5-0.4-0.3-0.30.0-0.3
Pavlov. Cond. change in total contacts0.30.81.20.70.30.91.01.0-1.01.1
Pavlov. Cond. index score0.50.71.00.50.50.81.01.0-1.01.0
Pavlov. Cond. latency score0.20.30.60.20.20.50.60.6-0.80.7
Pavlov. Cond. lever contacts1.52.22.81.21.01.41.61.6-1.51.7
Pavlov. Cond. magazine entry number0.10.20.5-0.0-0.2-0.1-0.4-0.40.7-0.5
Pavlov. Cond. intertrial magazine entries1.02.22.9-1.2-1.4-1.4-1.5-1.51.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.50.81.10.60.50.81.01.0-1.11.1
Pavlov. Cond. response bias1.41.92.41.21.11.31.51.5-1.51.5
Time in closed arm before self-admin2.13.74.72.21.32.01.91.9-1.92.1
Time in closed arm after self-admin3.23.65.32.31.91.61.71.7-2.11.9
Time in open arm before self-admin0.70.91.4-0.7-0.1-1.0-1.1-1.10.9-1.2
Time in open arm after self-admin2.32.53.4-1.8-1.5-1.4-1.6-1.61.6-1.6
Bone: periosteal estimation0.30.61.41.20.90.50.70.7-0.70.6
Bone: periosteal perimeter1.12.23.01.71.51.41.51.5-1.41.5
Bone: post-yield work0.81.42.01.21.01.01.21.2-1.21.4
Progressive ratio test 1 active lever presses0.81.41.8-1.1-1.0-1.4-1.2-1.21.2-1.2
Progressive ratio test 1 breakpoint0.61.11.4-1.0-0.8-1.2-1.0-1.01.0-1.1
Progressive ratio test 1 inactive lever presses0.20.40.70.60.80.80.70.7-0.50.5
Progressive ratio test 2 active lever presses0.71.01.8-0.2-0.5-1.3-1.1-1.11.1-1.1
Progressive ratio test 2 breakpoint0.70.91.7-0.2-0.5-1.3-1.1-1.11.1-1.0
Progressive ratio test 2 inactive lever presses0.00.10.50.70.5-0.3-0.1-0.10.1-0.2
Incentive Sensitization - Responses0.10.40.70.6-0.0-0.8-0.7-0.70.6-0.7
Incentive Sensitization - Breakpoint0.10.30.50.70.0-0.7-0.5-0.50.5-0.5
Sum of active levers in priming session hrs 5-63.12.94.1-2.0-1.7-1.7-1.5-1.51.7-1.6
Progressive ratio0.00.10.20.50.2-0.3-0.3-0.30.1-0.2
Food seeking constrained by brief footshock0.00.00.1-0.0-0.30.00.20.20.00.1
Seeking ratio, punishment vs. effort0.20.41.0-1.0-1.0-0.4-0.2-0.20.5-0.3
Retroperitoneal fat weight0.21.13.71.91.00.90.80.8-0.80.6
Reaction time number correct0.31.21.91.40.61.10.80.8-1.31.2
Reaction time mean minus median0.42.53.6-1.9-1.4-1.7-1.5-1.51.4-1.5
Reaction time mean minus median AUC0.53.54.5-2.0-1.6-2.1-1.8-1.81.7-2.0
Reaction time num false alarms0.71.21.5-1.2-1.2-0.7-1.2-1.21.1-1.0
Reaction time num false alarms AUC0.71.51.9-1.3-1.3-0.8-1.4-1.41.2-1.2
Reaction time trials correct on left0.31.21.91.40.61.10.80.8-1.31.2
Reaction time trials on left0.31.11.81.30.51.10.80.8-1.31.2
Reaction time mean0.51.11.8-1.3-0.7-1.3-0.9-0.90.9-1.2
Reaction time mean AUC0.61.42.1-1.5-0.8-1.4-1.0-1.01.0-1.3
Median of all reaction times0.30.50.9-0.9-0.4-1.0-0.5-0.50.6-0.8
Reaction time omissions1.22.02.3-1.5-1.5-1.3-1.3-1.31.3-1.4
Reaction time false alarm rate1.52.12.7-1.6-1.4-1.1-1.5-1.51.5-1.5
Reaction time premature initiation rate0.30.50.9-1.0-0.8-0.2-0.7-0.70.5-0.8
Reaction time premature initiations0.00.10.4-0.3-0.60.3-0.3-0.3-0.1-0.2
Std. dev. reaction times0.62.23.3-1.8-1.3-1.6-1.3-1.31.2-1.5
Reaction time trials completed0.31.11.81.30.51.10.80.8-1.31.2
Reaction time trials AUC0.31.21.81.40.51.10.90.9-1.31.3
Run reversals in cocaine runway, females0.10.10.3-0.2-0.60.40.10.1-0.10.2
Run reversals in cocaine runway, males0.70.82.81.31.70.70.30.3-0.60.0
Latency to leave start box in cocaine runway4.56.17.42.42.51.92.62.6-2.52.7
Latency to leave start box in cocaine runway, F6.88.59.72.92.82.73.03.0-3.13.0
Latency to leave start box in cocaine runway, M0.30.30.60.40.8-0.40.60.6-0.20.7
Std. dev. time between licks in bursts0.40.81.31.10.80.90.90.9-1.00.7
Total sessions with >9 infusions0.00.00.1-0.20.00.20.10.1-0.30.1
Short access day 1 total inactive lever presses0.20.31.0-0.5-1.0-0.5-0.4-0.40.6-0.5
Short access day 10 total inactive lever presses0.21.32.11.51.21.11.11.1-1.11.0
Short access day 1 total infusions0.00.10.2-0.0-0.00.50.30.3-0.40.3
Short access day 10 total infusions0.00.00.10.20.3-0.10.00.0-0.20.0
Short access total infusions0.20.20.40.30.40.50.50.5-0.70.5
Short access day 1 locomotion0.20.40.60.70.80.60.50.5-0.70.6
Short access day 10 total locomotion0.00.10.30.20.5-0.0-0.2-0.2-0.1-0.2
Short access total locomotion0.10.20.40.40.70.40.20.2-0.50.1
One hour access (0.3 mA shock)0.50.61.1-0.6-0.9-1.0-0.6-0.61.0-0.6
Compulsive drug intake1.42.03.5-1.9-1.7-1.4-1.0-1.01.6-1.1
One hour access (shock baseline)0.20.61.41.21.00.60.50.5-0.60.6
Social response proportion1.92.43.8-1.9-1.9-1.6-1.4-1.41.5-1.0
Social responses0.10.10.5-0.2-0.70.30.20.20.20.4
Social time0.10.10.20.30.50.5-0.0-0.00.2-0.2
Soleus weight1.85.46.32.32.12.32.32.3-2.42.5
Bone: stiffness0.10.10.30.60.5-0.2-0.3-0.30.00.3
Tibialis anterior weight0.00.10.4-0.3-0.6-0.00.40.40.3-0.2
Time to tail flick, vehicle, before self-admin2.32.83.5-1.9-1.4-1.7-1.6-1.61.8-1.6
Time to tail flick, vehicle, after self-admin0.51.12.11.51.00.90.90.9-1.01.0
Time to tail flick, test, before self-admin0.60.70.90.70.60.90.90.9-1.00.9
Time to tail flick, test, after self-admin1.01.01.61.00.80.81.01.0-1.31.2
Delta time to tail flick, vehicle, before/after SA4.64.96.52.51.82.32.22.2-2.22.3
Delta time to tail flick, test, before/after SA0.30.30.5-0.7-0.7-0.6-0.6-0.60.5-0.4
Tibia length0.61.53.21.81.01.11.01.0-1.41.2
Ambulatory time before self-admin0.31.01.8-0.5-0.5-1.0-1.1-1.11.3-1.1
Ambulatory time after self-admin0.10.10.30.5-0.00.20.40.40.00.6
Bone: tissue strength0.91.01.91.41.10.90.80.8-1.10.8
Total heroin consumption0.60.71.3-1.2-1.0-0.8-0.4-0.41.0-0.6
Bone: trabecular number0.10.20.70.80.50.20.40.4-0.20.6
Bone: trabecular spacing0.00.10.1-0.20.20.2-0.1-0.10.2-0.4
Bone: trabecular thickness4.05.67.12.41.72.42.32.3-2.62.7
Bone: trabecular tissue density0.10.21.0-0.2-0.40.1-0.2-0.2-0.2-1.0
Water consumed over 24 hours0.10.20.3-0.5-0.3-0.3-0.5-0.50.3-0.3
Number of responses in last shaping day0.81.01.61.21.31.00.80.8-1.10.9