Hub : Genes

LOC134479947

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability LOC134479947 0.34 0.1 0.0e+00 0.38 0.37 0.36 0.37 5.5e-21 7.3e-21 1.0e-19 1.9e-20
2 Brain mRNA stability LOC134479947 0.54 0.11 0.0e+00 0.52 0.52 0.53 0.53 1.5e-55 1.8e-55 7.0e-58 1.7e-57
3 IC mRNA stability LOC134479947 0.3 0.13 4.9e-12 0.21 0.23 0.22 0.22 2.6e-09 3.2e-10 1.5e-09 7.6e-10
4 PL mRNA stability LOC134479947 0.08 0.04 1.0e-10 0.11 0.1 0.11 0.11 9.4e-12 3.7e-11 1.3e-11 9.9e-12
5 OFC mRNA stability LOC134479947 0.41 0.12 6.3e-10 0.25 0.32 0.26 0.3 1.2e-06 2.9e-08 6.1e-07 8.8e-08
6 pVTA gene expression LOC134479947 0.03 0.02 8.8e-03 0.01 0.01 0.01 0.01 4.4e-02 2.0e-02 2.7e-02 3.7e-02
7 NAcc gene expression LOC134479947 0.02 0.01 1.9e-03 0.01 0.01 0.01 0 2.9e-02 5.6e-03 1.0e-02 1.5e-01
8 Brain gene expression LOC134479947 0.09 0.05 2.8e-06 0.07 0.07 0.07 0.07 8.8e-07 1.9e-07 8.2e-07 5.0e-07
9 Adipose gene expression LOC134479947 0.25 0.1 0.0e+00 0.15 0.15 0.15 0.15 1.2e-16 2.5e-16 3.1e-16 8.1e-17
10 PL gene expression LOC134479947 0.12 0.06 1.1e-07 0.09 0.07 0.08 0.08 1.1e-09 4.3e-08 6.3e-09 3.9e-09
11 Liver gene expression LOC134479947 0.05 0.03 1.0e-03 0.03 0.01 0.02 0.02 8.5e-04 7.5e-03 5.9e-03 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.6-0.6-0.7-0.5-0.6-0.8-0.5-0.3-0.10.0-0.1-0.1
Area under the delay curve0.10.10.2-0.5-0.2-0.5-0.4-0.2-0.1-0.30.40.30.40.4
BMI with tail0.82.73.91.72.01.92.01.81.91.91.01.11.01.0
BMI without tail0.10.20.80.20.20.3-0.10.10.00.1-0.8-0.4-0.9-0.9
Body weight0.83.46.62.12.22.32.62.22.12.01.10.70.60.6
Weight adjusted by age0.40.61.50.4-0.1-0.3-0.3-0.1-0.6-0.8-1.0-1.2-1.2-1.2
Bone surface0.50.92.0-0.4-0.7-0.5-0.6-0.8-1.0-0.9-0.7-1.3-1.4-1.4
Bone volume0.10.20.4-0.1-0.3-0.2-0.2-0.4-0.4-0.3-0.3-0.6-0.7-0.7
Breakpoint value in progressive ratio session0.20.20.6-0.1-0.00.4-0.10.10.20.50.40.50.80.8
Number of licking bursts0.30.50.8-0.8-0.8-0.8-0.9-0.7-0.8-0.8-0.4-0.5-0.5-0.5
Context. condit. distance diff. score4.14.910.13.23.12.52.92.92.52.11.00.30.60.6
Locomotion velocity, session 10.70.72.40.1-0.2-0.2-0.3-0.1-0.6-0.8-0.6-1.5-1.4-1.4
Locomotion distance, session 12.73.44.9-1.9-2.0-2.0-1.9-1.8-2.1-2.2-1.3-1.6-1.7-1.7
Locomotion velocity, session 20.20.20.30.60.60.40.30.30.20.2-0.1-0.5-0.5-0.5
Locomotion distance, session 21.31.83.7-1.9-1.9-1.4-1.9-1.7-1.5-1.20.00.1-0.1-0.1
Locomotion velocity, session 30.40.41.40.30.4-0.10.20.1-0.2-0.4-0.6-1.2-1.1-1.1
Locomotion distance, session 31.92.13.5-1.3-1.3-1.7-1.1-1.2-1.5-1.9-1.3-1.5-1.5-1.5
Stereotopy head waving bouts, day 30.50.61.21.01.11.10.90.80.80.80.5-0.00.10.1
Stereotopy head waving duration, day 32.22.65.52.32.32.21.91.91.71.70.6-0.10.10.1
Locomotion velocity, session 70.10.10.3-0.10.3-0.20.60.20.1-0.2-0.1-0.4-0.2-0.2
Locomotion distance, session 70.30.41.0-0.8-0.1-0.50.2-0.10.2-0.00.90.91.01.0
Stereotopy head waving bouts, day 71.61.83.41.81.31.01.51.10.50.2-0.9-1.8-1.8-1.8
Stereotopy head waving duration, day 71.21.52.81.71.31.01.51.10.60.4-0.9-1.5-1.4-1.4
Locomotion velocity, session 81.72.05.42.31.81.91.31.81.51.40.80.20.30.3
Locomotion distance, session 80.50.71.91.41.30.90.81.00.80.70.2-0.20.00.0
Degree of sensitization distance4.24.35.91.41.92.01.81.72.22.42.12.32.42.4
Degree of sensitization stereotypy1.21.42.61.51.00.81.31.00.40.1-0.8-1.6-1.5-1.5
Conditioned locomotion0.30.41.01.01.00.30.90.70.60.2-0.2-0.2-0.2-0.2
Cocaine response after cond. corrected0.00.00.20.10.20.00.10.10.0-0.1-0.3-0.4-0.3-0.3
Cocaine response after cond. not corrected0.10.10.30.20.30.1-0.20.0-0.1-0.1-0.6-0.6-0.5-0.5
Cocaine response before conditioning0.10.10.5-0.10.0-0.1-0.7-0.4-0.3-0.2-0.5-0.2-0.2-0.2
Saline control response0.30.40.80.60.70.4-0.10.2-0.1-0.1-0.7-0.8-0.9-0.9
Bone: connectivity density0.00.10.2-0.3-0.4-0.2-0.2-0.4-0.3-0.10.10.0-0.1-0.1
Bone: cortical apparent density0.70.92.0-1.4-1.1-1.2-1.2-1.2-1.1-1.1-0.4-0.3-0.4-0.4
Bone: cortical area1.11.72.81.61.71.71.51.51.51.40.70.40.50.5
Bone: cortical porosity0.20.20.50.50.70.50.50.40.50.5-0.10.10.20.2
Bone: cortical porosity0.80.91.91.41.41.21.21.11.01.00.0-0.10.00.0
Bone: cortical thickness0.91.52.70.50.81.10.70.91.21.31.51.71.71.7
Bone: cortical thickness1.51.73.00.90.81.10.71.11.31.41.61.71.71.7
Bone: cortical tissue density0.60.81.8-1.3-1.1-1.2-1.1-1.1-1.0-1.0-0.4-0.3-0.3-0.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.5-0.2-0.1-0.4-0.3-0.10.10.60.40.40.4
Condit. Reinf. active-inactive response ratio0.20.20.30.50.60.50.50.50.50.40.50.10.10.1
Condit. Reinf. active responses0.60.71.9-1.3-1.0-0.9-1.4-1.2-0.8-0.6-0.00.30.20.2
Condit. Reinf. inactive responses1.41.74.1-1.8-1.6-1.5-2.0-1.7-1.3-1.1-0.60.1-0.1-0.1
Incentive salience index mean0.30.30.6-0.8-0.5-0.4-0.7-0.6-0.2-0.10.60.70.60.6
Condit. Reinf. lever presses0.40.51.3-1.1-0.8-0.9-1.1-1.0-0.6-0.50.10.30.20.2
Condit. Reinf. active minus inactive responses0.50.72.30.00.00.60.30.40.50.71.51.11.11.1
Condit. Reinf. active-inactive response ratio0.70.92.6-0.00.10.80.50.50.71.01.61.21.21.2
Condit. Reinf. active responses0.60.91.81.00.81.10.91.01.01.01.30.70.70.7
Condit. Reinf. inactive responses0.60.71.81.41.30.91.01.10.90.60.60.10.20.2
Condit. Reinf. lever presses0.10.10.4-0.5-0.6-0.1-0.6-0.5-0.3-0.00.40.30.20.2
Condit. Reinf. lever reinforcers received0.50.71.70.70.50.90.60.70.80.91.30.80.80.8
Conditioned reinforcement - actives0.40.61.10.50.80.70.81.01.00.81.00.70.70.7
Conditioned reinforcement - inactives0.81.22.70.10.40.9-0.00.60.91.21.61.61.51.5
Conditioned locomotion1.92.43.31.21.71.61.51.61.81.81.61.51.41.4
Patch foraging indifference point 0 sec0.20.31.1-0.8-0.7-0.2-1.1-0.7-0.5-0.00.00.20.20.2
Patch foraging indifference point AUC0.20.40.9-0.9-0.7-0.7-0.4-0.5-0.7-0.9-0.0-0.5-0.2-0.2
Delay disc. indifference point, 0s delay0.91.01.71.11.31.10.81.01.21.10.50.80.90.9
Delay disc. indifference point, 16s delay0.70.71.4-1.2-1.1-1.1-1.0-1.0-0.9-1.0-0.1-0.1-0.2-0.2
Delay disc. indifference point, 2s delay0.20.20.60.20.4-0.00.40.30.40.20.60.60.80.8
Delay disc. indifference point, 24s delay0.40.51.0-0.8-0.5-0.8-0.4-0.4-0.7-1.0-0.2-0.8-0.7-0.7
Delay disc. indifference point, 4s delay0.40.51.30.30.30.5-0.20.30.50.61.10.90.90.9
Delay disc. indifference point, 8s delay0.40.41.3-1.1-0.7-1.0-0.8-0.7-0.6-0.70.10.20.10.1
Indifference point function ln k0.40.71.81.31.11.01.00.90.91.00.20.20.00.0
Indifference point function log k0.40.71.81.31.11.01.00.90.91.00.20.20.00.0
Patch foraging total patch changes 0 sec0.20.41.4-0.9-0.9-0.4-1.2-0.9-0.6-0.2-0.10.20.10.1
Patch foraging total patch changes 12 sec0.00.10.2-0.20.10.2-0.1-0.10.00.20.50.30.30.3
Patch foraging total patch changes 18 sec0.10.20.5-0.2-0.30.2-0.6-0.20.00.30.70.60.70.7
Patch foraging total patch changes 24 sec0.20.30.7-0.8-0.7-0.5-0.8-0.7-0.7-0.6-0.3-0.4-0.2-0.2
Patch foraging total patch changes 6 sec0.10.10.8-0.3-0.40.2-0.9-0.3-0.30.00.20.10.30.3
Patch foraging time to switch 0 sec0.10.20.7-0.3-0.1-0.4-0.1-0.5-0.2-0.2-0.6-0.3-0.8-0.8
Patch foraging water rate 0 sec0.10.10.40.2-0.30.5-0.40.1-0.00.30.30.40.60.6
Patch foraging water rate 12 sec0.40.71.1-0.7-1.0-0.6-1.0-0.8-0.9-0.7-0.8-0.8-1.1-1.1
Patch foraging water rate 18 sec0.91.42.5-1.0-1.6-0.9-1.4-1.4-1.5-1.1-0.9-1.0-1.0-1.0
Patch foraging water rate 24 sec0.10.10.50.5-0.10.7-0.00.20.20.60.30.1-0.2-0.2
Patch foraging water rate 6 sec1.11.72.5-0.9-1.3-1.1-1.2-1.2-1.5-1.4-1.3-1.6-1.3-1.3
Seeking ratio, delayed vs. immediate footshock2.02.46.0-2.4-2.1-1.9-1.8-2.1-1.6-1.4-0.5-0.2-0.1-0.1
Distance traveled before self-admin0.50.62.3-0.4-0.10.0-0.3-0.20.30.61.01.51.21.2
Distance traveled after self-admin0.30.30.9-0.50.10.5-0.30.10.30.60.70.90.70.7
Extensor digitorum longus weight0.20.61.2-0.9-0.7-0.5-0.9-0.8-0.8-0.6-1.1-0.7-0.7-0.7
Bone: elastic displacement0.40.51.50.4-0.00.10.20.1-0.3-0.4-0.9-1.2-1.2-1.2
Bone: elastic work1.52.04.22.11.72.01.71.71.51.60.60.10.20.2
Bone: endosteal estimation0.61.43.41.51.00.80.80.60.10.0-1.1-1.8-1.8-1.7
Bone: endosteal perimeter0.91.83.41.81.61.11.71.20.70.4-0.9-1.7-1.5-1.5
Epididymis fat weight1.86.110.52.73.12.63.22.72.82.61.91.51.61.6
Delta time in closed arm before/after self-admin0.80.81.90.60.60.50.40.70.80.71.10.91.41.4
Delta time in open arm before/after self-admin0.90.92.00.1-0.4-0.6-0.6-0.5-0.8-0.9-1.2-1.4-1.4-1.4
Diff in mean of infusions in LGA sessions0.10.20.40.40.30.50.40.40.30.30.60.30.40.4
Delay discount exponential model param0.10.10.30.50.20.50.40.30.20.4-0.4-0.2-0.3-0.3
Extinction: sum of active levers before priming0.91.01.31.21.01.11.11.11.01.00.80.70.90.9
Active lever presses in extinction session 60.20.20.60.80.60.70.20.50.40.40.10.20.10.1
Bone: final force1.52.43.21.61.61.81.41.61.71.81.51.31.31.3
Bone: final moment1.62.53.71.71.71.91.51.71.71.81.61.21.21.2
Food consumed during 24 hour testing period1.52.12.61.51.51.61.41.51.61.61.41.21.31.3
Glucose0.10.10.6-0.10.10.0-0.2-0.20.20.40.20.70.20.2
Heart weight6.19.517.04.13.93.93.03.73.53.41.71.61.51.5
Delay discount hyperbolic model param0.10.10.30.30.00.30.30.10.00.2-0.5-0.4-0.5-0.5
Intermittent access intake day 1-15 change0.10.20.7-0.8-0.6-0.5-0.5-0.6-0.4-0.2-0.20.1-0.1-0.1
Intermittent access intake escalation0.20.41.1-1.0-0.7-0.7-0.7-0.7-0.6-0.5-0.3-0.1-0.3-0.3
Intermittent access intake escalation 20.50.51.4-1.2-0.8-0.9-0.8-0.9-0.7-0.6-0.6-0.2-0.6-0.6
Intermitt. access day 1 inactive lever presses0.72.74.51.11.01.60.51.11.62.01.92.12.12.1
Intermitt. access day 15 inactive lever presses1.32.75.90.60.81.30.10.81.41.82.22.42.32.3
Intermitt. access escalation Index0.10.10.4-0.4-0.4-0.2-0.7-0.3-0.2-0.10.10.1-0.1-0.1
Intermittent access day 1 total infusions1.01.62.41.01.11.10.91.21.31.31.61.31.61.6
Intermittent access day 15 total infusions0.00.10.2-0.4-0.1-0.1-0.3-0.00.10.10.30.30.40.4
Intermittent access terminal intake (last 3 days)0.00.00.2-0.50.0-0.3-0.1-0.10.0-0.10.10.10.20.2
Intermittent access total infusions0.30.40.80.20.50.40.40.50.70.60.80.70.90.9
Intermittent access day 1 locomotion0.60.81.60.70.50.60.20.50.81.01.11.21.31.3
Intermittent access day 15 total locomotion0.10.20.40.30.30.40.40.40.60.60.60.60.40.4
Intermittent access total locomotion0.50.50.90.30.50.50.60.50.80.80.90.90.90.9
Intermittent access standard deviation0.51.12.30.30.90.80.70.71.21.31.01.51.21.2
Left kidney weight8.438.965.18.17.87.87.27.57.06.74.32.82.52.5
Right kidney weight10.447.370.28.48.28.37.98.07.77.55.33.93.73.7
Cocaine induced anxiety0.71.02.00.20.60.91.40.91.01.11.31.11.01.0
Post-drug Anxiety0.10.10.4-0.7-0.5-0.20.4-0.2-0.2-0.20.1-0.1-0.1-0.1
Baseline Anxiety1.82.13.1-1.2-1.3-1.7-1.4-1.4-1.6-1.8-1.5-1.4-1.3-1.3
Tail length0.93.45.5-1.2-1.6-1.5-1.6-1.5-1.9-1.8-2.2-2.0-2.4-2.4
Length with tail0.10.51.20.90.60.71.10.70.30.2-0.3-0.7-0.8-0.8
Length without tail1.75.39.32.52.42.63.02.52.52.52.11.31.61.6
Times rat made contact with spout0.91.01.31.01.01.00.81.11.00.91.10.91.01.0
Lifetime Intake1.51.83.00.71.11.10.91.21.41.41.71.61.71.7
Liver weight, left0.50.81.41.11.10.31.21.00.5-0.1-0.6-0.9-1.0-1.0
Liver weight, right0.91.63.81.71.91.01.71.61.10.6-0.5-0.6-1.1-1.1
Locomotor activity1.01.53.51.61.51.61.91.61.31.20.3-0.3-0.2-0.2
Locomotor testing distance0.10.10.5-0.7-0.4-0.3-0.4-0.4-0.3-0.3-0.2-0.2-0.1-0.1
Locomotor testing rearing0.61.32.81.41.71.31.21.51.41.10.50.40.50.5
Locomotion in novel chamber1.01.33.3-0.3-0.4-0.8-1.0-0.6-0.9-1.1-1.8-1.7-1.4-1.4
Locomotion in novel chamber post-restriction0.81.42.3-1.2-1.2-1.5-1.0-1.3-1.2-1.4-1.1-1.0-1.0-1.0
Fecal boli incidents, locomotor time 10.10.20.4-0.3-0.5-0.4-0.4-0.5-0.5-0.4-0.2-0.1-0.6-0.6
Change in fecal boli incidents, locomotor task0.30.31.10.60.40.31.10.70.2-0.10.0-0.8-0.7-0.7
Time >=10cm from walls, locomotor time 10.10.10.10.20.30.30.40.20.20.20.30.10.20.2
Bouts of movement, locomotor time 10.40.41.50.10.40.10.90.40.50.20.60.31.21.2
Total resting periods, locomotor time 10.60.62.4-0.10.3-0.00.80.30.50.30.80.81.51.5
Rest time, locomotor task time 11.61.93.70.51.10.81.31.01.31.31.61.71.91.9
Distance moved, locomotor task time 10.20.21.01.00.60.5-0.10.50.30.2-0.4-0.4-0.4-0.4
Vertical activity count, locomotor time 10.00.10.3-0.0-0.10.1-0.6-0.1-0.2-0.0-0.3-0.3-0.6-0.6
Time >=10cm from walls, locomotor time 20.20.20.4-0.5-0.3-0.6-0.4-0.5-0.5-0.6-0.6-0.5-0.3-0.3
Bouts of movement, locomotor time 20.81.23.50.20.70.50.80.61.00.91.21.31.91.9
Total resting periods, locomotor time 20.71.33.70.10.60.50.70.60.90.91.31.41.91.9
Rest time, locomotor task time 20.10.10.3-0.4-0.2-0.10.2-0.00.00.00.50.30.50.5
Distance moved, locomotor task time 20.40.41.21.01.10.70.30.80.70.6-0.10.00.50.5
Vertical activity count, locomotor time 20.10.10.30.40.50.4-0.00.40.20.2-0.3-0.3-0.5-0.5
Light reinforcement 10.20.41.20.20.20.1-0.40.0-0.2-0.3-0.7-1.1-1.0-1.0
Light reinforcement 20.30.51.40.41.20.70.80.80.90.70.50.40.50.5
Bone: marrow area0.71.53.31.61.10.90.90.70.20.1-1.0-1.8-1.7-1.7
Bone: maximum diameter2.34.48.52.92.82.72.72.62.32.10.90.10.30.3
Bone: maximum force2.13.85.52.22.22.31.92.12.22.21.81.41.51.5
Bone: maximum moment2.44.16.32.32.32.52.02.32.22.31.81.41.41.4
Mean time between licks in bursts0.20.50.9-0.9-0.8-0.9-0.9-0.8-0.7-0.7-0.7-0.2-0.2-0.2
Mean num. licks in bursts1.31.92.91.71.71.51.71.71.61.41.00.90.90.9
Cd content in liver0.91.02.11.31.21.01.31.41.10.70.80.40.50.5
Co content in liver0.30.41.00.10.20.50.10.50.50.50.71.01.00.9
Cu content in liver4.75.69.1-2.7-3.0-2.5-3.0-2.9-2.7-2.3-1.6-1.2-1.5-1.5
Fe content in liver0.50.61.61.10.91.30.70.70.60.90.0-0.3-0.3-0.3
K content in liver0.70.61.4-0.6-1.0-0.8-1.2-1.1-1.0-0.8-0.4-0.2-0.5-0.5
Mg content in liver0.50.51.3-0.7-1.0-0.7-1.2-1.0-0.7-0.40.20.50.20.2
Mn content in liver0.10.10.50.70.1-0.1-0.10.0-0.1-0.3-0.2-0.5-0.5-0.5
Na content in liver1.71.82.9-1.4-1.7-1.5-1.6-1.7-1.5-1.3-1.1-0.6-0.8-0.8
Rb content in liver0.30.30.80.50.30.80.20.60.50.60.90.60.60.6
Se content in liver0.70.91.1-0.8-0.9-1.0-0.8-0.9-1.0-1.0-0.8-0.9-1.0-1.0
Sr content in liver1.41.22.5-1.6-1.3-1.4-1.6-1.2-1.1-1.0-0.70.20.00.0
Zn content in liver0.20.20.40.1-0.3-0.3-0.2-0.2-0.4-0.5-0.4-0.6-0.7-0.7
Bone: minimum diameter0.30.50.80.90.80.60.80.60.40.3-0.4-0.8-0.8-0.8
Time in familiar zone, hab. session 10.10.00.10.00.1-0.20.30.2-0.0-0.30.0-0.4-0.3-0.3
Time in novel zone, hab. session 10.40.41.31.20.81.00.50.60.50.7-0.6-0.2-0.2-0.2
Total zone transitions, hab. session 13.44.86.8-2.2-2.4-2.5-2.2-2.2-2.5-2.6-1.6-1.8-1.9-1.9
Total locomotion distance, hab. session 13.34.77.1-1.4-1.7-2.0-1.7-1.8-2.3-2.5-2.2-2.7-2.7-2.7
Locomotion velocity, hab. session 13.04.35.5-1.6-1.9-2.0-1.9-1.9-2.2-2.4-1.9-2.2-2.3-2.3
Time in familiar zone, hab. session 20.50.51.2-0.3-0.0-0.7-0.1-0.2-0.4-0.8-1.1-1.1-0.9-0.9
Time in novel zone, hab. session 20.30.30.80.60.20.90.20.40.40.70.70.70.50.5
Total zone transitions, hab. session 20.40.51.5-0.7-0.9-0.7-1.2-0.9-0.9-0.8-0.0-0.3-0.4-0.4
Total locomotion distance, hab. session 20.40.61.4-0.7-0.9-0.8-1.2-0.9-0.9-0.8-0.4-0.4-0.5-0.5
Locomotion velocity, hab. session 20.91.22.4-1.1-1.3-1.1-1.6-1.3-1.3-1.1-0.6-0.6-0.7-0.7
Novel to familiar place preference ratio1.41.54.42.11.31.51.71.51.00.8-0.3-0.7-0.6-0.6
Novelty place preference1.81.95.42.31.61.62.01.81.10.9-0.3-0.8-0.6-0.6
Time in novel zone, NPP test2.32.56.92.61.81.92.32.01.41.1-0.2-0.7-0.6-0.6
Total zone transitions, NPP test2.73.95.3-1.9-2.2-2.1-2.3-2.0-2.3-2.3-1.4-1.6-1.7-1.7
Total locomotion distance, NPP test1.31.72.4-1.2-1.6-1.4-1.5-1.4-1.5-1.5-0.9-1.1-1.2-1.1
Locomotion velocity, NPP test2.13.03.9-1.8-1.9-1.9-1.9-1.9-2.0-1.9-1.3-1.3-1.3-1.3
Intraocular pressure0.10.20.60.50.40.20.80.60.40.10.3-0.0-0.0-0.0
Delta distance traveled before/after self-admin0.30.40.70.70.70.80.50.80.30.2-0.2-0.7-0.6-0.6
Delta ambulatory time before/after self-admin0.40.51.11.00.81.00.61.00.40.3-0.1-0.7-0.6-0.6
Parametrial fat weight0.10.30.8-0.20.0-0.70.1-0.2-0.3-0.7-0.9-0.6-0.7-0.7
Pavlov. Cond. lever latency0.20.30.80.90.60.60.80.80.50.4-0.2-0.4-0.3-0.3
Pavlov. Cond. magazine entry latency0.40.51.0-1.0-0.6-0.7-0.8-0.6-0.3-0.20.50.90.90.9
Pavlov. Cond. change in total contacts0.60.61.1-1.0-0.7-0.5-1.1-0.7-0.3-0.10.81.10.90.9
Pavlov. Cond. index score0.50.61.6-0.8-0.3-0.3-0.5-0.40.00.10.91.31.21.2
Pavlov. Cond. latency score0.40.51.2-0.7-0.3-0.2-0.5-0.4-0.00.10.81.11.11.1
Pavlov. Cond. lever contacts0.81.02.4-1.6-1.1-1.2-1.3-1.3-0.9-0.70.10.50.40.4
Pavlov. Cond. magazine entry number0.50.71.41.10.60.70.70.60.20.2-0.8-1.2-1.1-1.1
Pavlov. Cond. intertrial magazine entries0.50.61.4-1.1-1.2-0.7-1.0-1.0-0.9-0.6-0.3-0.2-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.61.3-0.9-0.4-0.5-0.6-0.5-0.1-0.10.81.11.11.1
Pavlov. Cond. response bias0.60.81.7-1.3-0.7-0.8-0.9-0.8-0.4-0.30.71.11.01.0
Pavlov. Cond. lever latency0.20.30.90.70.90.21.00.90.60.0-0.1-0.3-0.1-0.1
Pavlov. Cond. magazine entry latency1.51.94.9-2.1-2.2-1.1-1.7-1.8-1.2-0.50.60.80.60.6
Pavlov. Cond. change in total contacts0.50.82.1-0.3-0.60.6-0.5-0.40.20.91.51.41.21.2
Pavlov. Cond. index score0.71.02.4-1.4-1.6-0.6-1.4-1.4-0.8-0.10.60.80.60.6
Pavlov. Cond. latency score1.01.33.2-1.7-1.8-0.7-1.6-1.6-1.0-0.30.60.80.60.6
Pavlov. Cond. lever contacts0.30.51.3-0.9-1.1-0.3-1.2-1.1-0.7-0.20.00.1-0.0-0.0
Pavlov. Cond. magazine entry number0.91.13.21.71.80.81.21.40.90.3-0.7-0.7-0.5-0.5
Pavlov. Cond. intertrial magazine entries2.94.45.72.22.42.11.82.32.32.11.81.92.02.0
Pavlov. Cond. lever-magazine prob. diff.0.81.12.9-1.6-1.7-0.7-1.4-1.5-1.0-0.30.40.60.40.4
Pavlov. Cond. response bias0.40.51.5-1.0-1.2-0.3-1.0-1.1-0.6-0.00.40.50.30.3
Time in closed arm before self-admin4.96.39.2-3.0-2.6-2.5-2.9-2.9-2.7-2.3-2.4-1.5-2.2-2.2
Time in closed arm after self-admin0.10.10.2-0.40.1-0.4-0.2-0.2-0.1-0.3-0.40.1-0.2-0.2
Time in open arm before self-admin0.10.10.20.1-0.2-0.30.5-0.0-0.1-0.3-0.1-0.30.30.3
Time in open arm after self-admin0.80.82.50.1-0.7-0.7-0.2-0.6-0.9-1.0-1.2-1.6-1.1-1.1
Bone: periosteal estimation0.71.53.51.91.61.51.41.30.90.8-0.4-1.1-1.0-0.9
Bone: periosteal perimeter1.72.96.32.52.41.92.52.11.71.3-0.1-0.8-0.6-0.6
Bone: post-yield work0.50.81.30.70.70.90.60.80.90.91.11.01.01.0
Progressive ratio test 1 active lever presses0.81.02.20.30.50.60.40.70.90.91.51.31.31.3
Progressive ratio test 1 breakpoint0.60.71.70.10.40.40.30.50.70.71.31.11.21.2
Progressive ratio test 1 inactive lever presses3.04.38.60.71.31.60.41.21.92.22.62.92.92.9
Progressive ratio test 2 active lever presses0.70.92.30.00.30.50.20.60.80.81.51.21.41.4
Progressive ratio test 2 breakpoint0.60.71.9-0.00.30.40.20.50.70.71.41.11.21.2
Progressive ratio test 2 inactive lever presses0.40.61.6-0.6-0.5-0.2-0.7-0.30.10.31.11.21.31.3
Incentive Sensitization - Responses0.10.10.4-0.2-0.10.1-0.20.10.10.20.60.40.60.6
Incentive Sensitization - Breakpoint0.20.20.7-0.10.00.2-0.00.20.30.30.80.60.80.8
Sum of active levers in priming session hrs 5-60.10.10.50.7-0.00.10.00.0-0.00.0-0.3-0.2-0.2-0.2
Progressive ratio0.00.00.1-0.3-0.20.1-0.1-0.3-0.10.20.10.30.20.2
Food seeking constrained by brief footshock1.31.53.10.61.41.31.81.51.51.31.20.90.90.9
Seeking ratio, punishment vs. effort0.50.71.10.61.00.71.01.01.00.80.90.60.70.7
Retroperitoneal fat weight2.811.720.54.14.43.94.54.14.03.62.41.71.41.4
Reaction time number correct1.42.63.9-1.6-1.6-1.9-1.3-1.5-1.7-2.0-1.6-1.9-1.3-1.3
Reaction time mean minus median0.10.20.60.80.60.40.10.40.20.2-0.7-0.3-0.5-0.5
Reaction time mean minus median AUC0.20.61.61.31.10.80.91.00.80.7-0.20.20.00.0
Reaction time num false alarms0.40.51.8-0.10.0-0.3-0.4-0.3-0.6-0.7-1.3-1.3-0.7-0.7
Reaction time num false alarms AUC0.40.72.3-0.2-0.2-0.4-0.7-0.4-0.7-0.8-1.4-1.5-0.7-0.7
Reaction time trials correct on left1.42.63.9-1.6-1.6-1.9-1.3-1.5-1.7-2.0-1.6-1.9-1.3-1.3
Reaction time trials on left1.52.84.2-1.6-1.6-1.9-1.4-1.5-1.8-2.0-1.6-2.0-1.4-1.4
Reaction time mean0.10.10.7-0.1-0.4-0.2-0.8-0.3-0.3-0.1-0.40.1-0.4-0.4
Reaction time mean AUC0.10.10.5-0.2-0.4-0.2-0.7-0.3-0.2-0.1-0.30.1-0.3-0.3
Median of all reaction times0.20.31.1-0.5-0.8-0.5-1.1-0.7-0.5-0.3-0.30.0-0.4-0.4
Reaction time omissions0.30.51.0-0.1-0.5-0.6-0.7-0.4-0.7-0.8-1.0-0.9-0.6-0.6
Reaction time false alarm rate0.10.20.50.50.70.60.10.40.30.4-0.4-0.10.30.3
Reaction time premature initiation rate0.20.20.5-0.7-0.30.4-0.3-0.4-0.00.50.70.50.40.4
Reaction time premature initiations0.20.31.4-1.2-0.8-0.3-0.6-0.8-0.6-0.30.2-0.2-0.0-0.0
Std. dev. reaction times0.20.30.90.90.70.60.20.70.50.5-0.3-0.1-0.4-0.4
Reaction time trials completed1.52.84.2-1.6-1.6-1.9-1.4-1.5-1.8-2.0-1.6-2.0-1.4-1.4
Reaction time trials AUC1.22.33.4-1.4-1.5-1.7-1.2-1.4-1.6-1.8-1.5-1.9-1.3-1.3
Run reversals in cocaine runway, females0.90.91.4-0.8-0.6-1.1-0.7-0.8-1.0-1.2-1.0-1.2-1.1-1.1
Run reversals in cocaine runway, males0.40.41.01.00.60.60.90.90.40.10.1-0.6-0.3-0.3
Latency to leave start box in cocaine runway0.10.10.20.10.40.30.40.30.40.40.20.40.20.2
Latency to leave start box in cocaine runway, F0.20.20.2-0.5-0.4-0.4-0.3-0.5-0.5-0.5-0.5-0.4-0.4-0.4
Latency to leave start box in cocaine runway, M1.00.91.30.71.01.01.01.01.11.10.81.10.80.8
Std. dev. time between licks in bursts0.50.71.7-1.1-1.3-0.7-1.2-1.2-1.0-0.6-0.1-0.1-0.2-0.2
Total sessions with >9 infusions6.88.310.02.62.93.02.42.83.13.23.12.92.82.8
Short access day 1 total inactive lever presses2.53.25.31.71.62.30.91.71.92.32.01.81.61.6
Short access day 10 total inactive lever presses0.30.81.40.61.21.11.01.11.11.00.60.50.70.7
Short access day 1 total infusions3.03.95.61.82.02.31.11.92.22.42.02.11.91.9
Short access day 10 total infusions1.82.33.21.01.51.41.11.31.71.71.71.81.61.6
Short access total infusions4.86.18.52.02.32.51.72.32.72.82.92.82.62.6
Short access day 1 locomotion1.11.42.11.01.21.20.60.91.31.51.21.41.21.2
Short access day 10 total locomotion0.40.72.40.10.20.1-0.1-0.10.50.70.61.31.51.5
Short access total locomotion2.12.53.81.21.41.40.91.21.61.81.62.01.91.9
One hour access (0.3 mA shock)0.20.21.0-1.0-0.3-0.5-0.2-0.3-0.0-0.00.20.50.30.3
Compulsive drug intake0.10.10.4-0.1-0.5-0.10.00.0-0.2-0.20.70.1-0.2-0.2
One hour access (shock baseline)0.10.10.8-0.9-0.1-0.5-0.3-0.4-0.0-0.0-0.20.20.30.3
Social response proportion0.30.30.80.60.40.70.30.30.60.90.20.80.00.0
Social responses0.30.41.2-0.4-0.3-0.2-0.2-0.3-0.5-0.5-0.7-0.8-1.1-1.1
Social time0.91.22.5-1.5-1.5-1.4-1.6-1.5-1.2-1.0-0.5-0.1-0.0-0.0
Soleus weight0.00.10.30.2-0.20.1-0.4-0.0-0.10.10.60.40.40.4
Bone: stiffness1.22.02.81.51.71.71.31.51.61.71.11.11.11.1
Tibialis anterior weight0.41.23.4-1.9-1.5-1.1-1.6-1.3-1.1-0.8-0.40.30.30.3
Time to tail flick, vehicle, before self-admin0.20.20.80.90.20.5-0.10.1-0.00.1-0.2-0.4-0.5-0.5
Time to tail flick, vehicle, after self-admin2.12.85.1-1.0-1.2-1.3-1.0-1.2-1.6-1.7-2.0-2.1-2.3-2.3
Time to tail flick, test, before self-admin0.30.31.10.40.90.41.10.70.60.30.30.10.40.4
Time to tail flick, test, after self-admin0.40.40.7-0.6-0.6-0.8-0.3-0.5-0.5-0.7-0.6-0.6-0.8-0.8
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.4-0.10.10.20.00.00.1-0.1-0.1-0.1-0.1
Delta time to tail flick, test, before/after SA2.02.03.5-1.3-1.6-1.4-1.9-1.6-1.5-1.3-1.1-0.9-1.4-1.4
Tibia length0.51.42.31.41.31.51.51.51.31.21.10.20.30.3
Ambulatory time before self-admin0.20.31.0-0.2-0.0-0.0-0.4-0.10.20.40.71.00.70.7
Ambulatory time after self-admin0.40.51.0-1.0-0.9-0.5-0.9-0.8-0.8-0.6-0.4-0.4-0.5-0.5
Bone: tissue strength0.10.10.20.20.20.40.50.30.20.20.1-0.4-0.3-0.3
Total heroin consumption0.60.71.30.80.70.90.30.80.70.81.00.91.11.1
Bone: trabecular number0.10.20.4-0.4-0.3-0.60.1-0.4-0.4-0.6-0.5-0.6-0.7-0.7
Bone: trabecular spacing1.41.92.31.31.41.41.51.51.51.41.41.11.21.2
Bone: trabecular thickness0.10.20.5-0.4-0.5-0.4-0.7-0.7-0.5-0.2-0.4-0.1-0.2-0.2
Bone: trabecular tissue density0.91.43.9-1.4-1.6-0.9-2.0-1.6-1.4-0.8-0.8-0.1-0.2-0.2
Water consumed over 24 hours0.40.61.10.90.91.10.51.00.80.80.70.50.50.5
Number of responses in last shaping day1.31.44.2-0.5-0.00.2-0.9-0.40.40.91.22.12.02.0