Hub : Genes

LOC134479947

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability LOC134479947 0.34 0.1 0.0e+00 0.38 0.37 0.36 0.37 5.5e-21 7.3e-21 1.1e-19 1.7e-20
2 Brain mRNA stability LOC134479947 0.54 0.11 0.0e+00 0.52 0.52 0.53 0.53 1.5e-55 1.8e-55 7.0e-58 1.8e-57
3 IC mRNA stability LOC134479947 0.3 0.13 4.9e-12 0.21 0.23 0.22 0.22 2.6e-09 3.2e-10 1.5e-09 7.4e-10
4 PL mRNA stability LOC134479947 0.08 0.04 1.0e-10 0.11 0.1 0.11 0.11 9.4e-12 3.7e-11 1.3e-11 1.0e-11
5 OFC mRNA stability LOC134479947 0.41 0.12 6.3e-10 0.25 0.32 0.26 0.3 1.2e-06 2.9e-08 6.2e-07 9.0e-08
6 pVTA gene expression LOC134479947 0.03 0.02 8.8e-03 0.01 0.01 0.01 0.01 4.4e-02 2.0e-02 2.7e-02 3.7e-02
7 NAcc gene expression LOC134479947 0.02 0.01 1.9e-03 0.01 0.01 0.01 0 2.9e-02 5.6e-03 1.0e-02 1.5e-01
8 Brain gene expression LOC134479947 0.09 0.05 2.8e-06 0.07 0.07 0.07 0.07 8.8e-07 1.9e-07 8.2e-07 5.7e-07
9 Adipose gene expression LOC134479947 0.25 0.1 0.0e+00 0.15 0.15 0.15 0.15 1.2e-16 2.5e-16 3.1e-16 8.2e-17
10 PL gene expression LOC134479947 0.12 0.06 1.1e-07 0.09 0.07 0.08 0.08 1.1e-09 4.3e-08 6.3e-09 3.9e-09
11 Liver gene expression LOC134479947 0.05 0.03 1.0e-03 0.03 0.01 0.02 0.02 8.5e-04 7.5e-03 5.9e-03 2.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.60.60.7-0.50.6-0.8-0.5-0.3-0.10.00.10.1
Area under the delay curve0.10.10.20.50.2-0.50.4-0.2-0.1-0.30.40.3-0.4-0.4
BMI with tail0.82.73.9-1.7-2.01.9-2.01.81.91.91.01.1-1.0-1.0
BMI without tail0.00.20.8-0.2-0.20.30.10.10.00.1-0.8-0.40.90.9
Body weight0.83.46.6-2.1-2.22.3-2.62.22.12.01.10.7-0.6-0.6
Weight adjusted by age0.20.61.5-0.40.1-0.30.3-0.1-0.6-0.8-1.0-1.21.21.2
Bone surface0.50.92.00.40.7-0.50.6-0.8-1.0-0.9-0.7-1.31.41.4
Bone volume0.10.20.40.10.3-0.20.2-0.4-0.4-0.3-0.3-0.60.70.7
Breakpoint value in progressive ratio session0.10.20.60.10.00.40.10.10.20.50.40.5-0.8-0.8
Number of licking bursts0.20.50.80.80.8-0.80.9-0.7-0.8-0.8-0.4-0.50.50.5
Context. condit. distance diff. score4.14.910.1-3.2-3.12.5-2.92.92.52.11.00.3-0.6-0.6
Locomotion velocity, session 10.60.72.3-0.10.2-0.20.3-0.1-0.6-0.8-0.6-1.51.41.4
Locomotion distance, session 12.73.44.91.92.0-2.01.9-1.8-2.1-2.2-1.3-1.61.71.7
Locomotion velocity, session 20.20.20.3-0.6-0.60.4-0.30.30.20.2-0.1-0.50.50.5
Locomotion distance, session 21.31.83.71.91.9-1.41.9-1.7-1.5-1.20.00.10.10.1
Locomotion velocity, session 30.40.41.4-0.3-0.4-0.1-0.20.1-0.2-0.4-0.6-1.21.11.1
Locomotion distance, session 31.82.13.51.31.3-1.71.1-1.2-1.5-1.9-1.3-1.51.51.5
Stereotopy head waving bouts, day 30.50.61.2-1.0-1.11.1-0.90.80.80.80.5-0.0-0.1-0.1
Stereotopy head waving duration, day 32.12.65.5-2.3-2.32.2-1.91.91.71.70.6-0.0-0.1-0.1
Locomotion velocity, session 70.10.10.30.1-0.3-0.2-0.60.20.1-0.2-0.1-0.40.20.2
Locomotion distance, session 70.30.41.00.80.1-0.5-0.2-0.10.2-0.00.90.9-1.0-1.0
Stereotopy head waving bouts, day 71.61.83.4-1.8-1.31.0-1.51.10.50.2-0.9-1.81.81.8
Stereotopy head waving duration, day 71.21.52.8-1.7-1.31.0-1.51.10.60.4-0.9-1.51.41.4
Locomotion velocity, session 81.72.05.4-2.3-1.81.9-1.31.81.51.40.80.2-0.3-0.3
Locomotion distance, session 80.50.71.9-1.4-1.30.9-0.81.00.80.70.2-0.2-0.0-0.0
Degree of sensitization distance4.04.35.9-1.4-1.92.0-1.81.72.22.42.12.3-2.4-2.4
Degree of sensitization stereotypy1.21.42.6-1.5-1.00.8-1.31.00.40.1-0.8-1.61.51.5
Conditioned locomotion0.30.41.0-1.0-1.00.3-0.90.70.60.2-0.2-0.20.20.2
Cocaine response after cond. corrected0.00.00.2-0.1-0.20.0-0.10.10.0-0.1-0.3-0.40.30.3
Cocaine response after cond. not corrected0.10.10.3-0.2-0.30.10.20.0-0.1-0.1-0.6-0.60.50.5
Cocaine response before conditioning0.10.10.50.1-0.0-0.10.7-0.4-0.3-0.2-0.5-0.20.20.2
Saline control response0.30.40.8-0.6-0.70.40.10.2-0.1-0.1-0.7-0.80.90.9
Bone: connectivity density0.00.10.20.30.4-0.20.2-0.4-0.3-0.10.10.00.10.1
Bone: cortical apparent density0.60.92.01.41.1-1.21.2-1.2-1.1-1.1-0.4-0.30.40.4
Bone: cortical area1.01.72.8-1.6-1.71.7-1.51.51.51.40.70.4-0.5-0.5
Bone: cortical porosity0.20.20.5-0.5-0.70.5-0.50.40.50.5-0.10.1-0.2-0.2
Bone: cortical porosity0.80.91.9-1.4-1.41.2-1.21.11.01.00.0-0.1-0.0-0.0
Bone: cortical thickness0.91.52.7-0.5-0.81.1-0.70.91.21.31.51.7-1.7-1.7
Bone: cortical thickness1.41.73.0-0.9-0.81.1-0.71.11.31.41.61.7-1.7-1.7
Bone: cortical tissue density0.50.81.81.31.1-1.21.1-1.1-1.0-1.0-0.4-0.30.30.3
Condit. Reinf. active minus inactive responses0.10.10.30.50.2-0.10.4-0.3-0.10.10.60.4-0.4-0.4
Condit. Reinf. active-inactive response ratio0.20.20.3-0.5-0.60.5-0.50.50.50.40.50.1-0.1-0.1
Condit. Reinf. active responses0.60.71.91.31.0-0.91.4-1.2-0.8-0.6-0.00.3-0.2-0.2
Condit. Reinf. inactive responses1.31.74.11.81.6-1.52.0-1.7-1.3-1.1-0.60.10.10.1
Incentive salience index mean0.20.30.60.80.5-0.40.7-0.6-0.2-0.10.60.7-0.6-0.6
Condit. Reinf. lever presses0.40.51.31.10.8-0.91.1-1.0-0.6-0.50.10.3-0.2-0.2
Condit. Reinf. active minus inactive responses0.40.72.3-0.0-0.00.6-0.30.40.50.71.51.1-1.1-1.1
Condit. Reinf. active-inactive response ratio0.50.92.60.0-0.10.8-0.50.50.71.01.61.2-1.2-1.2
Condit. Reinf. active responses0.60.91.8-1.0-0.81.1-0.91.01.01.01.30.7-0.7-0.7
Condit. Reinf. inactive responses0.50.71.8-1.4-1.30.9-1.01.10.90.60.60.1-0.2-0.2
Condit. Reinf. lever presses0.10.10.40.50.6-0.10.6-0.5-0.3-0.00.40.3-0.2-0.2
Condit. Reinf. lever reinforcers received0.50.71.7-0.7-0.50.9-0.60.70.80.91.30.8-0.8-0.8
Conditioned reinforcement - actives0.20.61.1-0.5-0.80.7-0.81.01.00.81.00.7-0.7-0.7
Conditioned reinforcement - inactives0.41.22.7-0.1-0.40.90.00.60.91.21.61.6-1.5-1.5
Conditioned locomotion1.62.43.3-1.2-1.71.6-1.51.61.81.81.61.5-1.4-1.4
Patch foraging indifference point 0 sec0.10.31.10.80.7-0.21.1-0.7-0.5-0.00.00.2-0.2-0.2
Patch foraging indifference point AUC0.10.40.90.90.7-0.70.4-0.5-0.7-0.9-0.0-0.50.20.2
Delay disc. indifference point, 0s delay0.91.01.7-1.1-1.31.1-0.81.01.21.10.50.8-0.9-0.9
Delay disc. indifference point, 16s delay0.50.71.41.21.1-1.11.0-1.0-0.9-1.0-0.1-0.10.20.2
Delay disc. indifference point, 2s delay0.20.20.6-0.2-0.4-0.0-0.40.30.40.20.60.6-0.8-0.8
Delay disc. indifference point, 24s delay0.30.51.00.80.5-0.80.4-0.4-0.7-1.0-0.2-0.80.70.7
Delay disc. indifference point, 4s delay0.40.51.3-0.3-0.30.50.20.30.50.61.10.9-0.9-0.9
Delay disc. indifference point, 8s delay0.30.41.31.10.7-1.00.8-0.7-0.6-0.70.10.2-0.1-0.1
Indifference point function ln k0.20.71.8-1.3-1.11.0-1.00.90.91.00.20.2-0.0-0.0
Indifference point function log k0.20.71.8-1.3-1.11.0-1.00.90.91.00.20.2-0.0-0.0
Patch foraging total patch changes 0 sec0.10.41.40.90.9-0.41.2-0.9-0.6-0.2-0.10.2-0.1-0.1
Patch foraging total patch changes 12 sec0.00.10.20.2-0.10.20.1-0.10.00.20.50.3-0.3-0.3
Patch foraging total patch changes 18 sec0.10.20.50.20.30.20.6-0.20.00.30.70.6-0.7-0.7
Patch foraging total patch changes 24 sec0.10.30.70.80.7-0.50.8-0.7-0.7-0.6-0.3-0.40.20.2
Patch foraging total patch changes 6 sec0.10.10.80.30.40.20.9-0.3-0.30.00.20.1-0.3-0.3
Patch foraging time to switch 0 sec0.10.20.70.30.1-0.40.1-0.5-0.2-0.2-0.6-0.30.80.8
Patch foraging water rate 0 sec0.00.10.4-0.20.30.50.40.1-0.00.30.30.4-0.6-0.6
Patch foraging water rate 12 sec0.20.71.10.71.0-0.61.0-0.8-0.9-0.7-0.8-0.81.11.1
Patch foraging water rate 18 sec0.61.42.51.01.6-0.91.4-1.4-1.5-1.1-0.9-1.01.01.0
Patch foraging water rate 24 sec0.10.10.5-0.50.10.70.00.20.20.60.30.10.20.2
Patch foraging water rate 6 sec1.11.72.50.91.3-1.11.2-1.2-1.5-1.4-1.3-1.61.31.3
Seeking ratio, delayed vs. immediate footshock1.72.46.02.42.1-1.91.8-2.1-1.6-1.4-0.5-0.20.10.1
Distance traveled before self-admin0.30.62.30.40.10.00.3-0.20.30.61.01.5-1.2-1.2
Distance traveled after self-admin0.20.30.90.5-0.10.50.30.10.30.60.70.9-0.7-0.7
Extensor digitorum longus weight0.20.61.20.90.7-0.50.9-0.8-0.8-0.6-1.1-0.70.70.7
Bone: elastic displacement0.40.51.5-0.40.00.1-0.20.1-0.3-0.4-0.9-1.21.21.2
Bone: elastic work1.52.04.2-2.1-1.72.0-1.71.71.51.60.60.1-0.2-0.2
Bone: endosteal estimation0.61.43.4-1.5-1.00.8-0.80.60.10.0-1.1-1.81.81.7
Bone: endosteal perimeter0.71.83.4-1.8-1.61.1-1.71.20.70.4-0.9-1.71.51.5
Epididymis fat weight1.26.110.5-2.7-3.12.6-3.22.72.82.61.91.5-1.6-1.6
Delta time in closed arm before/after self-admin0.80.81.9-0.6-0.60.5-0.40.70.80.71.10.9-1.4-1.4
Delta time in open arm before/after self-admin0.80.92.0-0.10.4-0.60.6-0.5-0.8-0.9-1.2-1.41.41.4
Diff in mean of infusions in LGA sessions0.10.20.4-0.4-0.30.5-0.40.40.30.30.60.3-0.4-0.4
Delay discount exponential model param0.10.10.3-0.5-0.20.5-0.40.30.20.4-0.4-0.20.30.3
Extinction: sum of active levers before priming0.61.01.3-1.2-1.01.1-1.11.11.01.00.80.7-0.9-0.9
Active lever presses in extinction session 60.20.20.6-0.8-0.60.7-0.20.50.40.40.10.2-0.1-0.1
Bone: final force1.42.43.2-1.6-1.61.8-1.41.61.71.81.51.3-1.3-1.3
Bone: final moment1.62.53.7-1.7-1.71.9-1.51.71.71.81.61.2-1.2-1.2
Food consumed during 24 hour testing period1.12.12.6-1.5-1.51.6-1.41.51.61.61.41.2-1.3-1.3
Glucose0.10.10.60.1-0.10.00.2-0.20.20.40.20.7-0.2-0.2
Heart weight5.99.517.0-4.1-3.93.9-3.03.73.53.41.71.6-1.5-1.5
Delay discount hyperbolic model param0.10.10.3-0.3-0.00.3-0.30.10.00.2-0.5-0.40.50.5
Intermittent access intake day 1-15 change0.00.20.70.80.6-0.50.5-0.6-0.4-0.2-0.20.10.10.1
Intermittent access intake escalation0.10.41.11.00.7-0.70.7-0.7-0.6-0.5-0.3-0.10.30.3
Intermittent access intake escalation 20.30.51.41.20.8-0.90.8-0.9-0.7-0.6-0.6-0.20.60.6
Intermitt. access day 1 inactive lever presses0.22.74.5-1.1-1.01.6-0.51.11.62.01.92.1-2.1-2.1
Intermitt. access day 15 inactive lever presses0.52.75.9-0.6-0.81.3-0.10.81.41.82.22.4-2.3-2.3
Intermitt. access escalation Index0.00.10.40.40.4-0.20.7-0.3-0.2-0.10.10.10.10.1
Intermittent access day 1 total infusions0.61.62.4-1.0-1.11.1-0.91.21.31.31.61.3-1.6-1.6
Intermittent access day 15 total infusions0.00.10.20.40.1-0.10.3-0.00.10.10.30.3-0.4-0.4
Intermittent access terminal intake (last 3 days)0.00.00.20.5-0.0-0.30.1-0.10.0-0.10.10.1-0.2-0.2
Intermittent access total infusions0.30.40.8-0.2-0.50.4-0.40.50.70.60.80.7-0.9-0.9
Intermittent access day 1 locomotion0.40.81.6-0.7-0.50.6-0.20.50.81.01.11.2-1.3-1.3
Intermittent access day 15 total locomotion0.10.20.4-0.3-0.30.4-0.40.40.60.60.60.6-0.4-0.4
Intermittent access total locomotion0.50.50.9-0.3-0.50.5-0.60.50.80.80.90.9-0.9-0.9
Intermittent access standard deviation0.21.12.2-0.3-0.90.8-0.70.71.21.31.01.5-1.2-1.2
Left kidney weight4.838.965.1-8.1-7.87.8-7.27.57.06.74.32.8-2.5-2.5
Right kidney weight6.847.370.2-8.4-8.28.3-7.98.07.77.55.33.9-3.7-3.7
Cocaine induced anxiety0.41.02.0-0.2-0.60.9-1.40.91.01.11.31.1-1.0-1.0
Post-drug Anxiety0.10.10.40.70.5-0.2-0.4-0.2-0.2-0.20.1-0.10.10.1
Baseline Anxiety1.22.13.11.21.3-1.71.4-1.4-1.6-1.8-1.5-1.41.31.3
Tail length0.63.45.51.21.6-1.51.6-1.5-1.9-1.8-2.2-2.02.42.4
Length with tail0.10.51.2-0.9-0.60.7-1.10.70.30.2-0.3-0.70.80.8
Length without tail1.05.39.3-2.5-2.42.6-3.02.52.52.52.11.3-1.6-1.6
Times rat made contact with spout0.91.01.3-1.0-1.01.0-0.81.11.00.91.10.9-1.0-1.0
Lifetime Intake1.51.83.0-0.7-1.11.1-0.91.21.41.41.71.6-1.7-1.7
Liver weight, left0.40.81.4-1.1-1.10.3-1.21.00.5-0.1-0.6-0.91.01.0
Liver weight, right0.91.63.8-1.7-1.91.0-1.71.61.10.6-0.5-0.61.11.1
Locomotor activity1.01.53.5-1.6-1.51.6-1.91.61.31.20.3-0.30.20.2
Locomotor testing distance0.00.10.50.70.4-0.30.4-0.4-0.3-0.3-0.2-0.20.10.1
Locomotor testing rearing0.41.32.8-1.4-1.71.3-1.21.51.41.10.50.4-0.5-0.5
Locomotion in novel chamber1.01.33.30.30.4-0.81.0-0.6-0.9-1.1-1.8-1.71.41.4
Locomotion in novel chamber post-restriction0.51.42.31.21.2-1.51.0-1.3-1.2-1.4-1.1-1.01.01.0
Fecal boli incidents, locomotor time 10.10.20.40.30.5-0.40.4-0.5-0.5-0.4-0.2-0.10.60.6
Change in fecal boli incidents, locomotor task0.30.31.1-0.6-0.40.3-1.10.70.2-0.10.0-0.80.70.7
Time >=10cm from walls, locomotor time 10.00.10.1-0.2-0.30.3-0.40.20.20.20.30.1-0.2-0.2
Bouts of movement, locomotor time 10.30.41.5-0.1-0.40.1-0.90.40.50.20.60.3-1.2-1.2
Total resting periods, locomotor time 10.60.62.40.1-0.3-0.0-0.80.30.50.30.80.8-1.5-1.5
Rest time, locomotor task time 11.21.93.7-0.5-1.10.8-1.31.01.31.31.61.7-1.9-1.9
Distance moved, locomotor task time 10.10.21.0-1.0-0.60.50.10.50.30.2-0.4-0.40.40.4
Vertical activity count, locomotor time 10.00.10.30.00.10.10.6-0.1-0.2-0.0-0.3-0.30.60.6
Time >=10cm from walls, locomotor time 20.10.20.40.50.3-0.60.4-0.5-0.5-0.6-0.6-0.50.30.3
Bouts of movement, locomotor time 20.41.23.5-0.2-0.70.5-0.80.61.00.91.21.3-1.9-1.9
Total resting periods, locomotor time 20.31.33.7-0.1-0.60.5-0.70.60.90.91.31.4-1.9-1.9
Rest time, locomotor task time 20.10.10.30.40.2-0.1-0.2-0.00.00.00.50.3-0.5-0.5
Distance moved, locomotor task time 20.30.41.2-1.0-1.10.7-0.30.80.70.6-0.10.0-0.5-0.5
Vertical activity count, locomotor time 20.10.10.3-0.4-0.50.40.00.40.20.2-0.3-0.30.50.5
Light reinforcement 10.10.41.2-0.2-0.20.10.40.0-0.2-0.3-0.7-1.11.01.0
Light reinforcement 20.20.51.4-0.4-1.20.7-0.80.80.90.70.50.4-0.5-0.5
Bone: marrow area0.61.53.3-1.6-1.10.9-0.90.70.20.1-1.0-1.81.71.7
Bone: maximum diameter2.24.48.5-2.9-2.82.7-2.72.62.32.10.90.2-0.3-0.3
Bone: maximum force1.93.85.5-2.2-2.22.3-1.92.12.22.21.81.4-1.5-1.5
Bone: maximum moment2.24.16.3-2.3-2.32.5-2.02.32.22.31.81.4-1.4-1.4
Mean time between licks in bursts0.10.50.90.90.8-0.90.9-0.8-0.7-0.7-0.7-0.20.20.2
Mean num. licks in bursts0.71.92.9-1.7-1.71.5-1.71.71.61.41.00.9-0.9-0.9
Cd content in liver0.91.02.1-1.3-1.21.0-1.31.41.10.70.80.4-0.5-0.5
Co content in liver0.30.41.0-0.1-0.20.5-0.10.50.50.50.71.0-1.0-0.9
Cu content in liver4.75.69.12.73.0-2.53.0-2.9-2.7-2.3-1.6-1.21.51.5
Fe content in liver0.40.61.6-1.1-0.91.3-0.70.70.60.90.0-0.30.30.3
K content in liver0.70.61.40.61.0-0.81.2-1.1-1.0-0.8-0.4-0.20.50.5
Mg content in liver0.40.51.30.71.0-0.71.2-1.0-0.7-0.40.20.5-0.2-0.2
Mn content in liver0.10.10.5-0.7-0.1-0.10.10.0-0.1-0.3-0.2-0.50.50.5
Na content in liver1.61.82.91.41.7-1.51.6-1.7-1.5-1.3-1.1-0.60.80.8
Rb content in liver0.30.30.8-0.5-0.30.8-0.20.60.50.60.90.6-0.6-0.6
Se content in liver0.70.91.10.80.9-1.00.8-0.9-1.0-1.0-0.8-0.91.01.0
Sr content in liver1.41.22.51.61.3-1.41.6-1.2-1.1-1.0-0.70.2-0.0-0.0
Zn content in liver0.20.20.4-0.10.3-0.30.2-0.2-0.4-0.5-0.4-0.60.70.7
Bone: minimum diameter0.20.50.8-0.9-0.80.6-0.80.60.40.3-0.4-0.80.80.8
Time in familiar zone, hab. session 10.00.00.1-0.0-0.1-0.2-0.30.2-0.0-0.30.0-0.40.30.3
Time in novel zone, hab. session 10.40.41.3-1.2-0.81.0-0.50.60.50.7-0.6-0.20.20.2
Total zone transitions, hab. session 13.44.86.82.22.4-2.52.2-2.2-2.5-2.6-1.6-1.81.91.9
Total locomotion distance, hab. session 13.34.77.11.41.7-2.01.7-1.8-2.3-2.5-2.2-2.62.72.7
Locomotion velocity, hab. session 13.04.35.51.61.9-2.01.9-1.9-2.2-2.4-1.9-2.22.32.3
Time in familiar zone, hab. session 20.40.51.20.30.0-0.70.1-0.2-0.4-0.8-1.1-1.10.90.9
Time in novel zone, hab. session 20.30.30.8-0.6-0.20.9-0.20.40.40.70.70.7-0.5-0.5
Total zone transitions, hab. session 20.40.51.50.70.9-0.71.2-0.9-0.9-0.8-0.0-0.30.40.4
Total locomotion distance, hab. session 20.40.61.40.70.9-0.81.2-0.9-0.9-0.8-0.4-0.40.50.5
Locomotion velocity, hab. session 20.91.22.41.11.3-1.11.6-1.3-1.3-1.1-0.6-0.60.70.7
Novel to familiar place preference ratio1.11.54.4-2.1-1.31.5-1.71.51.00.8-0.3-0.70.60.6
Novelty place preference1.51.95.4-2.3-1.61.6-2.01.81.10.9-0.3-0.80.60.6
Time in novel zone, NPP test2.02.56.9-2.6-1.81.9-2.32.01.41.1-0.2-0.70.60.6
Total zone transitions, NPP test2.63.95.31.92.2-2.12.3-2.0-2.3-2.3-1.4-1.61.71.7
Total locomotion distance, NPP test1.31.72.41.21.6-1.41.5-1.4-1.5-1.5-0.9-1.11.21.1
Locomotion velocity, NPP test2.13.03.91.81.9-1.91.9-1.9-2.0-1.9-1.3-1.31.31.3
Intraocular pressure0.10.20.6-0.5-0.40.2-0.80.60.40.10.3-0.00.00.0
Delta distance traveled before/after self-admin0.30.40.7-0.7-0.70.8-0.50.80.30.2-0.2-0.70.60.6
Delta ambulatory time before/after self-admin0.30.51.1-1.0-0.81.0-0.61.00.40.3-0.1-0.70.60.6
Parametrial fat weight0.10.30.80.2-0.0-0.7-0.1-0.2-0.3-0.7-0.9-0.60.70.7
Pavlov. Cond. lever latency0.20.30.8-0.9-0.60.6-0.80.80.50.4-0.2-0.40.30.3
Pavlov. Cond. magazine entry latency0.40.51.01.00.6-0.70.8-0.6-0.3-0.20.50.9-0.9-0.9
Pavlov. Cond. change in total contacts0.60.61.11.00.7-0.51.1-0.7-0.3-0.10.81.1-0.9-0.9
Pavlov. Cond. index score0.50.61.60.80.3-0.30.5-0.40.00.10.91.2-1.2-1.2
Pavlov. Cond. latency score0.40.51.20.70.3-0.20.5-0.4-0.00.10.81.1-1.1-1.1
Pavlov. Cond. lever contacts0.81.02.41.61.1-1.21.3-1.3-0.9-0.70.10.5-0.4-0.4
Pavlov. Cond. magazine entry number0.50.71.4-1.1-0.60.7-0.70.60.20.2-0.8-1.21.11.1
Pavlov. Cond. intertrial magazine entries0.50.61.41.11.2-0.71.0-1.0-0.9-0.6-0.3-0.20.30.3
Pavlov. Cond. lever-magazine prob. diff.0.50.61.30.90.4-0.50.6-0.5-0.1-0.10.81.1-1.1-1.1
Pavlov. Cond. response bias0.60.81.71.30.7-0.80.9-0.8-0.4-0.30.71.1-1.0-1.0
Pavlov. Cond. lever latency0.20.30.9-0.7-0.90.2-1.00.90.60.0-0.1-0.30.10.1
Pavlov. Cond. magazine entry latency1.31.94.92.12.2-1.11.7-1.8-1.2-0.50.60.8-0.6-0.6
Pavlov. Cond. change in total contacts0.30.82.10.30.60.60.5-0.40.20.91.51.4-1.2-1.2
Pavlov. Cond. index score0.61.02.41.41.6-0.61.4-1.4-0.8-0.10.60.8-0.6-0.6
Pavlov. Cond. latency score0.81.33.21.71.8-0.71.6-1.6-1.0-0.30.60.8-0.6-0.6
Pavlov. Cond. lever contacts0.30.51.30.91.1-0.31.2-1.1-0.7-0.20.00.10.00.0
Pavlov. Cond. magazine entry number0.91.13.2-1.7-1.80.8-1.21.40.90.3-0.7-0.70.50.5
Pavlov. Cond. intertrial magazine entries2.04.45.7-2.2-2.42.1-1.82.32.32.11.81.9-2.0-2.0
Pavlov. Cond. lever-magazine prob. diff.0.71.12.91.61.7-0.71.4-1.5-1.0-0.30.40.6-0.4-0.4
Pavlov. Cond. response bias0.40.51.51.01.2-0.31.0-1.1-0.6-0.00.40.5-0.3-0.3
Time in closed arm before self-admin3.66.39.23.02.6-2.52.9-2.9-2.7-2.3-2.4-1.52.22.2
Time in closed arm after self-admin0.10.10.20.4-0.1-0.40.2-0.2-0.1-0.3-0.40.10.20.2
Time in open arm before self-admin0.10.10.2-0.10.2-0.3-0.5-0.0-0.1-0.3-0.1-0.3-0.3-0.3
Time in open arm after self-admin0.80.82.5-0.10.7-0.70.2-0.6-0.9-1.0-1.2-1.61.11.1
Bone: periosteal estimation0.61.53.5-1.9-1.61.5-1.41.30.90.8-0.4-1.11.00.9
Bone: periosteal perimeter1.52.96.3-2.5-2.41.9-2.52.11.71.3-0.1-0.80.60.6
Bone: post-yield work0.50.81.3-0.7-0.70.9-0.60.80.90.91.11.0-1.0-1.0
Progressive ratio test 1 active lever presses0.50.92.2-0.3-0.50.6-0.40.70.90.91.51.3-1.3-1.3
Progressive ratio test 1 breakpoint0.40.71.7-0.1-0.40.4-0.30.50.70.71.31.1-1.2-1.2
Progressive ratio test 1 inactive lever presses1.64.38.6-0.7-1.31.6-0.41.21.92.22.62.9-2.9-2.9
Progressive ratio test 2 active lever presses0.60.92.3-0.0-0.30.5-0.20.60.80.81.51.2-1.4-1.4
Progressive ratio test 2 breakpoint0.50.71.90.0-0.30.4-0.20.50.70.71.41.1-1.2-1.2
Progressive ratio test 2 inactive lever presses0.20.61.60.60.5-0.20.7-0.30.10.31.11.2-1.3-1.3
Incentive Sensitization - Responses0.00.10.40.20.10.10.20.10.10.20.60.4-0.6-0.6
Incentive Sensitization - Breakpoint0.10.20.70.1-0.00.20.00.20.30.30.80.6-0.8-0.8
Sum of active levers in priming session hrs 5-60.10.10.5-0.70.00.1-0.00.0-0.00.0-0.3-0.20.20.2
Progressive ratio0.00.00.10.30.20.10.1-0.3-0.10.20.10.3-0.2-0.2
Food seeking constrained by brief footshock1.21.53.1-0.6-1.41.3-1.81.51.51.31.20.9-0.9-0.9
Seeking ratio, punishment vs. effort0.30.71.1-0.6-1.00.7-1.01.01.00.80.90.6-0.7-0.7
Retroperitoneal fat weight2.611.720.5-4.1-4.43.9-4.54.14.03.62.41.7-1.4-1.4
Reaction time number correct0.72.63.91.61.6-1.91.3-1.5-1.7-2.0-1.6-1.91.31.3
Reaction time mean minus median0.00.20.6-0.8-0.60.4-0.10.40.20.2-0.7-0.30.50.5
Reaction time mean minus median AUC0.10.61.6-1.3-1.10.8-0.91.00.80.7-0.20.2-0.0-0.0
Reaction time num false alarms0.30.51.80.1-0.0-0.30.4-0.3-0.6-0.7-1.3-1.30.70.7
Reaction time num false alarms AUC0.30.72.30.20.2-0.40.7-0.4-0.7-0.8-1.4-1.50.70.7
Reaction time trials correct on left0.72.63.91.61.6-1.91.3-1.5-1.7-2.0-1.6-1.91.31.3
Reaction time trials on left0.82.84.21.61.6-1.91.4-1.5-1.8-2.0-1.6-2.01.41.4
Reaction time mean0.10.10.70.10.4-0.20.8-0.3-0.3-0.1-0.40.10.40.4
Reaction time mean AUC0.00.10.50.20.4-0.20.7-0.3-0.2-0.1-0.30.10.30.3
Median of all reaction times0.20.31.10.50.8-0.51.1-0.7-0.5-0.3-0.30.00.40.4
Reaction time omissions0.30.51.00.10.5-0.60.7-0.4-0.7-0.8-1.0-0.90.60.6
Reaction time false alarm rate0.10.20.5-0.5-0.70.6-0.10.40.30.4-0.4-0.1-0.3-0.3
Reaction time premature initiation rate0.10.20.50.70.30.40.3-0.4-0.00.50.70.5-0.4-0.4
Reaction time premature initiations0.10.31.41.20.8-0.30.6-0.8-0.6-0.30.2-0.20.00.0
Std. dev. reaction times0.10.30.9-0.9-0.70.6-0.20.70.50.5-0.3-0.10.40.4
Reaction time trials completed0.82.84.21.61.6-1.91.4-1.5-1.8-2.0-1.6-2.01.41.4
Reaction time trials AUC0.72.33.41.41.5-1.71.2-1.4-1.6-1.8-1.5-1.91.31.3
Run reversals in cocaine runway, females0.80.91.40.80.6-1.10.7-0.8-1.0-1.2-1.0-1.21.11.1
Run reversals in cocaine runway, males0.30.41.0-1.0-0.60.6-0.90.90.40.10.1-0.60.30.3
Latency to leave start box in cocaine runway0.10.10.2-0.1-0.40.3-0.40.30.40.40.20.4-0.2-0.2
Latency to leave start box in cocaine runway, F0.20.20.20.50.4-0.40.3-0.5-0.5-0.5-0.5-0.40.40.4
Latency to leave start box in cocaine runway, M1.00.91.3-0.7-1.01.0-1.01.01.11.10.81.1-0.8-0.8
Std. dev. time between licks in bursts0.40.71.71.11.3-0.71.2-1.2-1.0-0.6-0.1-0.10.20.2
Total sessions with >9 infusions6.78.310.0-2.6-2.93.0-2.42.83.13.23.12.9-2.8-2.8
Short access day 1 total inactive lever presses1.63.25.3-1.7-1.62.3-0.91.71.92.32.01.8-1.6-1.6
Short access day 10 total inactive lever presses0.10.81.4-0.6-1.21.1-1.01.11.11.00.60.5-0.7-0.7
Short access day 1 total infusions2.03.95.6-1.8-2.02.3-1.11.92.22.42.02.1-1.9-1.9
Short access day 10 total infusions1.42.33.2-1.0-1.51.4-1.11.31.71.71.71.8-1.6-1.6
Short access total infusions4.36.18.5-2.0-2.32.5-1.72.32.72.82.92.8-2.6-2.6
Short access day 1 locomotion0.81.42.1-1.0-1.21.2-0.60.91.31.51.21.4-1.2-1.2
Short access day 10 total locomotion0.20.72.4-0.1-0.20.10.1-0.10.50.70.61.3-1.5-1.5
Short access total locomotion1.62.53.8-1.2-1.41.4-0.91.21.61.81.62.0-1.9-1.9
One hour access (0.3 mA shock)0.20.21.01.00.3-0.50.2-0.3-0.0-0.00.20.5-0.3-0.3
Compulsive drug intake0.10.10.40.10.5-0.1-0.00.0-0.2-0.20.70.10.20.2
One hour access (shock baseline)0.10.10.80.90.1-0.50.3-0.4-0.0-0.0-0.20.2-0.3-0.3
Social response proportion0.20.30.8-0.6-0.40.7-0.30.30.60.90.20.8-0.0-0.0
Social responses0.30.41.20.40.3-0.20.2-0.3-0.5-0.5-0.7-0.81.11.1
Social time0.81.22.51.51.5-1.41.6-1.5-1.2-1.0-0.5-0.10.00.0
Soleus weight0.00.10.3-0.20.20.10.4-0.0-0.10.10.60.4-0.4-0.4
Bone: stiffness1.12.02.8-1.5-1.71.7-1.31.51.61.71.11.1-1.1-1.1
Tibialis anterior weight0.41.23.41.91.5-1.11.6-1.3-1.1-0.8-0.40.3-0.3-0.3
Time to tail flick, vehicle, before self-admin0.10.20.8-0.9-0.20.50.10.1-0.00.1-0.2-0.40.50.5
Time to tail flick, vehicle, after self-admin1.42.85.11.01.2-1.31.0-1.2-1.6-1.7-2.0-2.12.32.3
Time to tail flick, test, before self-admin0.30.31.1-0.4-0.90.4-1.10.70.60.30.30.1-0.4-0.4
Time to tail flick, test, after self-admin0.40.40.70.60.6-0.80.3-0.5-0.5-0.7-0.6-0.60.80.8
Delta time to tail flick, vehicle, before/after SA0.00.00.10.40.10.1-0.20.00.00.1-0.1-0.10.10.1
Delta time to tail flick, test, before/after SA1.62.03.51.31.6-1.41.9-1.6-1.5-1.3-1.1-0.91.41.4
Tibia length0.51.42.3-1.4-1.31.5-1.51.51.31.21.10.2-0.3-0.3
Ambulatory time before self-admin0.10.31.00.20.0-0.00.4-0.10.20.40.71.0-0.7-0.7
Ambulatory time after self-admin0.30.51.01.00.9-0.50.9-0.8-0.8-0.6-0.4-0.40.50.5
Bone: tissue strength0.10.10.2-0.2-0.20.4-0.50.30.20.20.1-0.40.30.3
Total heroin consumption0.60.71.3-0.8-0.70.9-0.30.80.70.81.00.9-1.1-1.1
Bone: trabecular number0.10.20.40.40.3-0.6-0.1-0.4-0.4-0.6-0.5-0.60.70.7
Bone: trabecular spacing1.31.92.3-1.3-1.41.4-1.51.51.51.41.41.1-1.2-1.2
Bone: trabecular thickness0.10.20.50.40.5-0.40.7-0.7-0.5-0.2-0.4-0.10.20.2
Bone: trabecular tissue density0.81.43.91.41.6-0.92.0-1.6-1.4-0.8-0.8-0.00.20.2
Water consumed over 24 hours0.30.61.1-0.9-0.91.1-0.51.00.80.80.70.5-0.5-0.5
Number of responses in last shaping day1.11.44.20.50.00.20.9-0.40.40.91.22.1-2.0-2.0