Hub : Genes

LOC134479938

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC134479938 0.09 0.04 9.6e-10 0.09 0.09 0.09 0.09 7.0e-10 6.4e-10 1.6e-10 1.9e-10
2 RMTg gene expression LOC134479938 0.13 0.07 8.5e-03 0.08 0.1 0.04 0.04 3.6e-03 1.4e-03 4.2e-02 3.4e-02
3 pVTA intron excision ratio chr7_113102356_113102760 0.09 0.05 2.8e-05 0.07 0.05 0.07 0.07 1.8e-06 6.4e-05 2.4e-06 4.1e-06
4 pVTA intron excision ratio chr7_113102356_113102850 0.09 0.05 1.1e-05 0.08 0.06 0.07 0.07 9.6e-07 2.5e-05 2.1e-06 4.3e-06
5 PL gene expression LOC134479938 0.07 0.03 8.8e-07 0.05 0.04 0.04 0.05 1.4e-06 1.6e-05 1.8e-05 4.7e-06
6 PL intron excision ratio chr7_113102356_113102760 0.05 0.03 4.6e-05 0.04 0.04 0.03 0.04 1.1e-05 3.3e-05 7.5e-04 3.1e-05
7 PL intron excision ratio chr7_113102356_113102850 0.04 0.02 1.7e-04 0.04 0.03 0.02 0.03 3.6e-05 2.6e-04 3.0e-03 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.00.00.20.50.1-0.10.10.1-0.00.0
Area under the delay curve1.31.55.02.22.00.5-0.5-0.70.6-0.6
BMI with tail0.30.92.0-1.4-1.3-0.50.51.1-0.70.7
BMI without tail0.30.81.4-0.6-1.1-0.60.61.2-0.90.9
Body weight0.52.39.2-2.6-3.00.2-0.20.4-0.10.1
Weight adjusted by age0.40.61.1-0.7-0.8-1.01.00.4-0.50.5
Bone surface0.10.20.40.60.20.3-0.3-0.60.4-0.4
Bone volume0.00.00.10.20.3-0.10.1-0.0-0.00.0
Breakpoint value in progressive ratio session0.20.20.40.30.20.6-0.6-0.60.3-0.3
Number of licking bursts0.40.61.71.01.3-0.30.30.4-0.80.8
Context. condit. distance diff. score2.83.412.2-3.5-2.3-1.11.11.1-1.21.2
Locomotion velocity, session 10.91.01.70.7-0.61.0-1.0-1.31.1-1.1
Locomotion distance, session 11.41.87.02.62.20.2-0.2-0.40.3-0.3
Locomotion velocity, session 20.10.10.2-0.1-0.40.3-0.3-0.40.4-0.4
Locomotion distance, session 22.73.811.63.42.11.3-1.3-1.61.5-1.5
Locomotion velocity, session 32.12.43.4-1.9-0.8-1.81.81.5-1.41.4
Locomotion distance, session 33.13.44.8-0.21.6-2.22.21.9-1.91.9
Stereotopy head waving bouts, day 31.11.31.7-0.2-1.31.2-1.2-1.11.2-1.2
Stereotopy head waving duration, day 32.22.67.7-1.3-2.81.5-1.5-1.21.3-1.3
Locomotion velocity, session 70.40.42.1-1.4-0.7-0.20.20.1-0.20.2
Locomotion distance, session 70.50.61.3-0.1-0.20.9-0.9-1.10.9-0.9
Stereotopy head waving bouts, day 72.62.96.9-2.6-2.3-1.21.21.5-1.21.2
Stereotopy head waving duration, day 72.73.26.7-2.6-2.2-1.41.41.7-1.41.4
Locomotion velocity, session 81.01.33.7-1.4-1.90.9-0.9-0.80.7-0.7
Locomotion distance, session 80.30.40.8-0.9-0.8-0.70.70.4-0.30.3
Degree of sensitization distance5.05.16.2-0.6-2.42.5-2.5-2.42.4-2.4
Degree of sensitization stereotypy2.42.75.3-2.3-1.9-1.41.41.5-1.31.3
Conditioned locomotion0.30.31.4-0.9-1.20.2-0.2-0.20.3-0.3
Cocaine response after cond. corrected1.01.22.10.4-0.70.9-0.9-1.31.5-1.5
Cocaine response after cond. not corrected0.50.61.20.3-0.50.6-0.6-0.91.1-1.1
Cocaine response before conditioning0.91.11.5-0.10.8-1.11.11.2-1.21.2
Saline control response0.50.71.1-1.0-0.5-1.11.10.6-0.80.8
Bone: connectivity density0.10.10.30.1-0.40.4-0.4-0.50.3-0.3
Bone: cortical apparent density2.33.24.9-0.70.8-2.22.21.8-2.02.0
Bone: cortical area0.71.11.8-0.1-0.81.2-1.2-1.31.1-1.1
Bone: cortical porosity1.01.11.4-0.5-1.11.0-1.0-1.11.2-1.2
Bone: cortical porosity2.52.83.3-0.8-1.81.8-1.8-1.71.8-1.8
Bone: cortical thickness0.30.41.10.71.10.5-0.5-0.70.5-0.5
Bone: cortical thickness1.11.32.21.51.41.2-1.2-1.10.6-0.6
Bone: cortical tissue density2.12.84.4-0.70.7-2.12.11.7-1.91.9
Condit. Reinf. active minus inactive responses0.10.10.30.30.6-0.30.3-0.2-0.20.2
Condit. Reinf. active-inactive response ratio0.40.40.8-0.70.1-0.90.90.2-0.60.6
Condit. Reinf. active responses0.60.71.00.71.0-0.90.90.5-0.90.9
Condit. Reinf. inactive responses1.01.21.40.81.1-1.01.01.2-1.21.2
Incentive salience index mean0.10.20.50.60.7-0.40.4-0.1-0.20.2
Condit. Reinf. lever presses0.10.20.40.50.6-0.40.40.3-0.30.3
Condit. Reinf. active minus inactive responses1.51.92.91.20.61.6-1.6-1.71.3-1.3
Condit. Reinf. active-inactive response ratio1.61.93.00.7-0.21.5-1.5-1.71.5-1.5
Condit. Reinf. active responses1.21.72.80.60.21.7-1.7-1.61.3-1.3
Condit. Reinf. inactive responses0.20.30.6-0.00.50.8-0.8-0.50.4-0.4
Condit. Reinf. lever presses0.20.30.80.90.80.3-0.3-0.40.5-0.5
Condit. Reinf. lever reinforcers received1.42.03.00.60.01.7-1.7-1.71.5-1.5
Conditioned reinforcement - actives1.01.73.51.41.91.1-1.1-1.01.2-1.2
Conditioned reinforcement - inactives2.53.66.32.52.21.9-1.9-1.61.5-1.5
Conditioned locomotion2.83.75.31.50.52.3-2.3-1.82.1-2.1
Patch foraging indifference point 0 sec0.20.30.50.6-0.60.5-0.5-0.70.5-0.5
Patch foraging indifference point AUC0.70.93.01.51.70.4-0.4-0.40.6-0.6
Delay disc. indifference point, 0s delay0.50.61.00.2-0.20.8-0.8-1.00.9-0.9
Delay disc. indifference point, 16s delay1.41.65.82.42.00.2-0.2-0.50.6-0.6
Delay disc. indifference point, 2s delay1.61.86.12.32.50.6-0.6-0.60.5-0.5
Delay disc. indifference point, 24s delay0.30.40.91.00.50.5-0.5-0.50.6-0.6
Delay disc. indifference point, 4s delay0.90.92.61.61.10.6-0.6-0.80.7-0.7
Delay disc. indifference point, 8s delay1.01.24.02.01.90.2-0.2-0.30.4-0.4
Indifference point function ln k1.01.74.9-2.2-1.9-0.70.70.7-0.90.9
Indifference point function log k1.01.74.9-2.2-1.9-0.70.70.7-0.90.9
Patch foraging total patch changes 0 sec0.10.20.90.9-0.10.3-0.3-0.40.2-0.2
Patch foraging total patch changes 12 sec0.81.11.90.70.11.0-1.0-1.41.3-1.3
Patch foraging total patch changes 18 sec1.72.63.61.70.31.9-1.9-1.91.5-1.5
Patch foraging total patch changes 24 sec0.20.41.30.91.20.4-0.4-0.60.1-0.1
Patch foraging total patch changes 6 sec1.01.63.11.80.61.2-1.2-1.31.2-1.2
Patch foraging time to switch 0 sec0.20.51.10.2-0.60.5-0.5-0.71.0-1.0
Patch foraging water rate 0 sec0.00.10.20.2-0.50.4-0.4-0.1-0.20.2
Patch foraging water rate 12 sec0.30.61.3-0.3-0.1-0.70.70.7-1.11.1
Patch foraging water rate 18 sec0.00.10.30.1-0.6-0.20.2-0.1-0.00.0
Patch foraging water rate 24 sec0.71.03.6-1.6-1.9-0.50.50.2-0.40.4
Patch foraging water rate 6 sec0.81.21.7-0.50.3-1.31.31.2-1.21.2
Seeking ratio, delayed vs. immediate footshock0.40.51.20.50.3-0.70.71.1-0.80.8
Distance traveled before self-admin0.81.02.51.60.80.8-0.8-0.71.1-1.1
Distance traveled after self-admin2.12.63.81.3-0.61.6-1.6-1.81.9-1.9
Extensor digitorum longus weight0.41.52.91.71.6-0.70.71.2-1.21.2
Bone: elastic displacement0.20.21.2-0.4-1.10.2-0.2-0.10.2-0.2
Bone: elastic work2.33.04.9-0.4-2.21.8-1.8-1.71.8-1.8
Bone: endosteal estimation1.22.64.7-0.5-2.21.6-1.6-1.71.6-1.6
Bone: endosteal perimeter0.91.95.5-1.2-2.31.2-1.2-1.21.0-1.0
Epididymis fat weight0.82.812.3-3.5-2.70.4-0.4-0.20.0-0.0
Delta time in closed arm before/after self-admin0.60.51.00.71.00.7-0.7-0.50.7-0.7
Delta time in open arm before/after self-admin0.10.10.30.5-0.1-0.10.1-0.00.2-0.2
Diff in mean of infusions in LGA sessions0.40.40.9-0.1-0.30.9-0.9-0.70.6-0.6
Delay discount exponential model param1.31.55.1-2.3-2.0-0.40.40.6-0.60.6
Extinction: sum of active levers before priming1.01.11.60.70.51.3-1.3-1.11.1-1.1
Active lever presses in extinction session 60.20.20.5-0.0-0.20.7-0.7-0.50.4-0.4
Bone: final force1.62.53.50.2-1.11.8-1.8-1.81.9-1.9
Bone: final moment1.83.04.20.2-1.21.9-1.9-1.92.1-2.1
Food consumed during 24 hour testing period0.91.31.9-0.2-0.41.3-1.3-1.41.2-1.2
Glucose0.20.30.5-0.0-0.30.7-0.7-0.70.5-0.5
Heart weight1.72.78.9-1.5-3.01.3-1.3-1.21.1-1.1
Delay discount hyperbolic model param1.41.55.1-2.3-2.2-0.30.30.5-0.50.5
Intermittent access intake day 1-15 change0.10.30.60.20.4-0.50.50.8-0.40.4
Intermittent access intake escalation0.30.50.90.30.6-0.90.91.0-0.70.7
Intermittent access intake escalation 20.30.40.60.30.4-0.60.60.8-0.70.7
Intermitt. access day 1 inactive lever presses0.62.24.10.1-1.11.4-1.4-2.01.7-1.7
Intermitt. access day 15 inactive lever presses0.51.01.21.10.31.1-1.1-1.01.1-1.1
Intermitt. access escalation Index0.71.01.4-0.01.2-1.01.01.1-1.11.1
Intermittent access day 1 total infusions2.33.74.71.81.12.2-2.2-2.22.0-2.0
Intermittent access day 15 total infusions0.81.23.21.81.50.7-0.7-0.70.8-0.8
Intermittent access terminal intake (last 3 days)1.01.33.11.81.31.0-1.0-0.70.9-0.9
Intermittent access total infusions3.84.45.52.41.52.3-2.3-2.02.1-2.1
Intermittent access day 1 locomotion2.02.63.81.70.91.9-1.9-1.41.5-1.5
Intermittent access day 15 total locomotion1.12.03.70.80.51.9-1.9-1.31.4-1.4
Intermittent access total locomotion2.83.35.91.00.42.4-2.4-1.72.0-2.0
Intermittent access standard deviation2.45.09.41.3-0.42.1-2.1-2.33.1-3.1
Left kidney weight2.913.434.9-4.7-5.92.8-2.8-2.62.6-2.6
Right kidney weight3.716.844.1-5.1-6.63.1-3.1-2.93.1-3.1
Cocaine induced anxiety0.30.41.2-1.1-0.70.9-0.9-0.0-0.00.0
Post-drug Anxiety0.70.81.8-1.3-0.8-0.40.40.9-1.01.0
Baseline Anxiety0.60.71.00.70.7-1.01.00.6-0.80.8
Tail length0.20.60.8-0.6-0.9-0.70.70.8-0.90.9
Length with tail0.41.66.6-2.2-2.6-0.00.00.1-0.10.1
Length without tail1.24.011.0-2.3-3.31.6-1.6-1.41.5-1.5
Times rat made contact with spout0.20.21.20.41.10.4-0.40.1-0.20.2
Lifetime Intake4.85.87.12.31.52.7-2.7-2.52.5-2.5
Liver weight, left0.71.23.7-1.9-0.3-0.90.90.9-0.90.9
Liver weight, right3.35.815.8-4.0-1.9-2.02.02.2-2.02.0
Locomotor activity0.40.72.1-1.5-1.40.3-0.3-0.30.3-0.3
Locomotor testing distance0.10.20.3-0.10.5-0.50.50.5-0.40.4
Locomotor testing rearing0.20.41.1-1.1-0.80.7-0.7-0.40.3-0.3
Locomotion in novel chamber3.34.25.70.01.4-2.42.42.2-2.42.4
Locomotion in novel chamber post-restriction0.81.43.00.81.7-1.21.20.9-1.11.1
Fecal boli incidents, locomotor time 11.52.23.21.3-0.21.5-1.5-1.61.8-1.8
Change in fecal boli incidents, locomotor task1.11.13.0-1.7-0.5-1.01.01.0-0.90.9
Time >=10cm from walls, locomotor time 11.41.41.7-0.3-1.31.3-1.3-1.31.3-1.3
Bouts of movement, locomotor time 10.20.21.0-1.0-0.30.3-0.3-0.20.1-0.1
Total resting periods, locomotor time 10.30.40.6-0.5-0.40.7-0.7-0.70.5-0.5
Rest time, locomotor task time 11.11.42.2-0.5-0.81.5-1.5-1.31.2-1.2
Distance moved, locomotor task time 10.71.01.3-0.8-0.5-1.11.11.1-1.11.1
Vertical activity count, locomotor time 10.10.20.4-0.6-0.5-0.50.50.6-0.40.4
Time >=10cm from walls, locomotor time 20.20.31.5-0.3-1.20.3-0.3-0.30.4-0.4
Bouts of movement, locomotor time 20.30.51.5-0.51.2-0.30.30.7-0.70.7
Total resting periods, locomotor time 20.20.31.9-0.01.40.1-0.10.3-0.30.3
Rest time, locomotor task time 20.40.60.80.50.40.8-0.8-0.90.8-0.8
Distance moved, locomotor task time 20.50.61.2-0.9-1.1-0.70.70.5-0.60.6
Vertical activity count, locomotor time 20.20.21.0-0.8-1.0-0.00.00.10.1-0.1
Light reinforcement 10.10.20.40.5-0.10.6-0.6-0.3-0.20.2
Light reinforcement 20.50.71.8-1.3-0.5-0.60.61.0-0.80.8
Bone: marrow area1.32.74.9-0.5-2.21.6-1.6-1.81.7-1.7
Bone: maximum diameter1.93.66.3-1.0-2.52.0-2.0-2.11.7-1.7
Bone: maximum force2.54.56.10.4-1.22.5-2.5-2.32.4-2.4
Bone: maximum moment2.84.96.70.3-1.42.5-2.5-2.52.6-2.6
Mean time between licks in bursts0.20.51.11.10.3-0.70.70.4-0.60.6
Mean num. licks in bursts0.20.31.3-1.1-0.50.4-0.4-0.10.4-0.4
Cd content in liver0.20.30.5-0.60.2-0.40.40.2-0.70.7
Co content in liver0.50.61.81.30.90.6-0.6-0.70.5-0.5
Cu content in liver2.02.46.82.62.3-1.01.01.0-0.90.9
Fe content in liver1.92.38.8-1.0-3.01.1-1.1-1.21.1-1.1
K content in liver0.10.10.20.50.4-0.30.30.4-0.10.1
Mg content in liver0.10.10.40.60.20.1-0.10.10.3-0.3
Mn content in liver0.50.60.9-0.50.8-1.01.00.8-0.50.5
Na content in liver0.10.10.40.6-0.0-0.20.20.4-0.10.1
Rb content in liver0.70.81.21.00.21.1-1.1-0.80.9-0.9
Se content in liver2.32.84.0-0.20.7-2.02.01.9-1.91.9
Sr content in liver3.22.85.81.32.4-1.51.51.6-1.51.5
Zn content in liver0.10.10.40.20.5-0.30.30.6-0.30.3
Bone: minimum diameter0.81.42.6-0.2-0.81.4-1.4-1.61.2-1.2
Time in familiar zone, hab. session 10.30.30.70.4-0.00.5-0.5-0.90.4-0.4
Time in novel zone, hab. session 10.40.41.2-1.0-1.1-0.10.10.6-0.20.2
Total zone transitions, hab. session 12.63.64.91.22.2-2.22.21.7-1.81.8
Total locomotion distance, hab. session 11.72.43.50.11.4-1.91.91.3-1.81.8
Locomotion velocity, hab. session 11.31.92.50.61.6-1.61.61.1-1.41.4
Time in familiar zone, hab. session 21.61.72.6-0.50.4-1.61.61.4-1.41.4
Time in novel zone, hab. session 21.61.62.50.6-0.11.6-1.6-1.51.4-1.4
Total zone transitions, hab. session 20.91.13.92.01.10.6-0.6-0.90.7-0.7
Total locomotion distance, hab. session 21.01.33.31.80.60.8-0.8-1.31.1-1.1
Locomotion velocity, hab. session 21.11.54.52.10.80.8-0.8-1.31.1-1.1
Novel to familiar place preference ratio0.80.82.3-1.5-1.3-0.50.50.6-0.70.7
Novelty place preference1.31.43.7-1.9-1.3-0.80.80.9-1.01.0
Time in novel zone, NPP test1.51.64.3-2.1-1.4-0.90.91.0-1.11.1
Total zone transitions, NPP test1.21.74.51.92.1-1.01.00.7-0.80.8
Total locomotion distance, NPP test0.30.42.01.40.9-0.10.1-0.40.2-0.2
Locomotion velocity, NPP test0.40.62.51.61.2-0.30.3-0.20.0-0.0
Intraocular pressure0.30.40.7-0.8-0.80.6-0.6-0.60.3-0.3
Delta distance traveled before/after self-admin0.90.92.8-0.9-1.70.7-0.7-0.80.8-0.8
Delta ambulatory time before/after self-admin1.01.22.8-0.5-1.71.0-1.0-1.11.0-1.0
Parametrial fat weight1.12.63.4-1.8-0.7-1.81.81.7-1.51.5
Pavlov. Cond. lever latency0.00.00.1-0.3-0.30.1-0.10.10.1-0.1
Pavlov. Cond. magazine entry latency0.50.71.91.41.10.5-0.5-0.60.5-0.5
Pavlov. Cond. change in total contacts1.21.33.51.91.50.8-0.8-1.00.8-0.8
Pavlov. Cond. index score0.40.60.80.90.60.7-0.7-0.80.7-0.7
Pavlov. Cond. latency score0.20.30.50.70.40.4-0.4-0.60.5-0.5
Pavlov. Cond. lever contacts0.20.20.80.90.70.1-0.1-0.30.2-0.2
Pavlov. Cond. magazine entry number0.60.71.9-1.4-1.4-0.40.40.5-0.50.5
Pavlov. Cond. intertrial magazine entries0.20.21.11.00.4-0.00.0-0.3-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.90.80.5-0.5-0.60.5-0.5
Pavlov. Cond. response bias0.50.61.51.21.10.5-0.5-0.60.6-0.6
Pavlov. Cond. lever latency0.20.30.5-0.60.5-0.70.70.3-0.50.5
Pavlov. Cond. magazine entry latency1.31.64.72.21.01.1-1.1-1.01.0-1.0
Pavlov. Cond. change in total contacts3.35.37.30.8-1.92.7-2.7-2.42.5-2.5
Pavlov. Cond. index score0.81.11.91.4-0.01.1-1.1-0.91.1-1.1
Pavlov. Cond. latency score0.91.22.51.60.11.2-1.2-0.91.2-1.2
Pavlov. Cond. lever contacts0.20.20.30.6-0.50.6-0.6-0.20.4-0.4
Pavlov. Cond. magazine entry number0.50.61.4-1.2-0.1-0.80.80.5-0.80.8
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.5-0.10.6-0.6-0.90.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.70.91.81.3-0.11.0-1.0-0.71.0-1.0
Pavlov. Cond. response bias0.71.01.41.1-0.31.2-1.2-0.81.0-1.0
Time in closed arm before self-admin0.20.32.11.40.3-0.00.00.1-0.00.0
Time in closed arm after self-admin0.30.30.70.10.00.8-0.8-0.50.5-0.5
Time in open arm before self-admin0.50.50.7-0.70.0-0.80.80.8-0.70.7
Time in open arm after self-admin0.80.91.7-0.20.4-1.21.21.3-0.90.9
Bone: periosteal estimation1.32.73.7-0.5-1.91.7-1.7-1.91.7-1.7
Bone: periosteal perimeter1.73.06.9-1.4-2.61.5-1.5-1.71.4-1.4
Bone: post-yield work1.31.93.61.20.21.9-1.9-1.31.3-1.3
Progressive ratio test 1 active lever presses2.83.54.61.91.12.1-2.1-1.81.9-1.9
Progressive ratio test 1 breakpoint2.53.13.81.91.11.9-1.9-1.61.8-1.8
Progressive ratio test 1 inactive lever presses3.65.27.22.50.92.7-2.7-2.72.0-2.0
Progressive ratio test 2 active lever presses2.42.83.41.61.81.7-1.7-1.71.6-1.6
Progressive ratio test 2 breakpoint2.42.83.71.71.91.6-1.6-1.61.6-1.6
Progressive ratio test 2 inactive lever presses1.01.75.61.92.40.8-0.8-0.70.6-0.6
Incentive Sensitization - Responses0.20.31.80.41.3-0.10.1-0.30.1-0.1
Incentive Sensitization - Breakpoint0.20.31.60.31.30.0-0.0-0.40.2-0.2
Sum of active levers in priming session hrs 5-60.00.00.00.0-0.20.1-0.1-0.20.1-0.1
Progressive ratio0.20.40.50.7-0.30.7-0.7-0.40.7-0.7
Food seeking constrained by brief footshock0.20.30.80.20.20.9-0.9-0.20.4-0.4
Seeking ratio, punishment vs. effort0.10.10.2-0.20.20.4-0.4-0.40.2-0.2
Retroperitoneal fat weight1.14.719.8-4.5-3.50.2-0.2-0.20.2-0.2
Reaction time number correct1.42.84.5-0.81.2-2.12.11.8-1.61.6
Reaction time mean minus median0.00.00.10.3-0.30.1-0.1-0.20.2-0.2
Reaction time mean minus median AUC0.00.10.4-0.6-0.70.0-0.0-0.10.1-0.1
Reaction time num false alarms0.10.20.2-0.3-0.1-0.40.40.5-0.50.5
Reaction time num false alarms AUC0.20.30.4-0.30.0-0.60.60.7-0.60.6
Reaction time trials correct on left1.42.84.5-0.81.2-2.12.11.8-1.61.6
Reaction time trials on left1.52.94.6-0.71.3-2.12.11.8-1.71.7
Reaction time mean0.10.10.60.1-0.8-0.00.00.00.3-0.3
Reaction time mean AUC0.00.10.30.0-0.6-0.10.10.10.2-0.2
Median of all reaction times0.10.10.50.1-0.7-0.10.10.10.3-0.3
Reaction time omissions0.40.52.11.01.4-0.60.60.1-0.00.0
Reaction time false alarm rate0.00.00.20.0-0.40.2-0.2-0.0-0.00.0
Reaction time premature initiation rate2.33.26.00.7-0.72.0-2.0-2.41.9-1.9
Reaction time premature initiations0.50.92.30.1-0.20.9-0.9-1.51.0-1.0
Std. dev. reaction times0.10.10.7-0.4-0.80.0-0.0-0.10.2-0.2
Reaction time trials completed1.52.94.6-0.71.3-2.12.11.8-1.71.7
Reaction time trials AUC1.22.33.8-0.91.0-2.02.01.6-1.51.5
Run reversals in cocaine runway, females0.70.71.5-0.9-0.4-0.50.50.4-1.21.2
Run reversals in cocaine runway, males0.10.10.30.0-0.20.3-0.3-0.30.5-0.5
Latency to leave start box in cocaine runway0.30.40.8-0.8-0.9-0.70.70.3-0.10.1
Latency to leave start box in cocaine runway, F0.10.10.30.3-0.5-0.40.40.00.1-0.1
Latency to leave start box in cocaine runway, M0.80.83.2-1.8-0.8-0.70.70.6-0.30.3
Std. dev. time between licks in bursts0.20.31.41.2-0.20.1-0.1-0.40.6-0.6
Total sessions with >9 infusions4.65.68.81.0-0.23.0-3.0-2.52.7-2.7
Short access day 1 total inactive lever presses6.18.010.22.2-1.23.2-3.2-3.13.1-3.1
Short access day 10 total inactive lever presses0.30.71.6-0.9-1.30.7-0.7-0.80.6-0.6
Short access day 1 total infusions2.33.14.21.2-0.32.0-2.0-1.92.0-2.0
Short access day 10 total infusions2.83.55.30.9-0.12.3-2.3-2.22.1-2.1
Short access total infusions4.86.19.01.60.33.0-3.0-2.72.7-2.7
Short access day 1 locomotion1.62.03.51.0-0.61.4-1.4-1.31.9-1.9
Short access day 10 total locomotion1.32.54.21.20.11.4-1.4-1.82.1-2.1
Short access total locomotion2.73.24.91.1-0.22.0-2.0-1.92.2-2.2
One hour access (0.3 mA shock)2.32.68.32.62.90.9-0.9-0.60.8-0.8
Compulsive drug intake0.30.41.80.41.3-0.60.60.4-0.20.2
One hour access (shock baseline)0.60.92.21.51.20.9-0.9-0.60.5-0.5
Social response proportion0.50.61.20.6-1.10.6-0.6-0.50.9-0.9
Social responses0.60.71.91.40.40.6-0.6-0.90.9-0.9
Social time1.21.76.42.51.40.5-0.5-0.91.0-1.0
Soleus weight0.30.91.31.01.20.9-0.9-1.00.9-0.9
Bone: stiffness1.72.83.60.1-1.41.9-1.9-1.71.9-1.9
Tibialis anterior weight0.92.910.53.03.2-0.30.30.4-0.60.6
Time to tail flick, vehicle, before self-admin0.20.20.40.10.00.6-0.6-0.70.1-0.1
Time to tail flick, vehicle, after self-admin0.10.10.5-0.0-0.7-0.30.30.10.0-0.0
Time to tail flick, test, before self-admin0.30.31.1-0.11.1-0.30.30.3-0.50.5
Time to tail flick, test, after self-admin0.40.41.20.10.3-0.60.61.1-0.70.7
Delta time to tail flick, vehicle, before/after SA0.50.51.00.6-0.70.5-0.5-0.51.0-1.0
Delta time to tail flick, test, before/after SA1.01.02.10.50.4-1.01.01.4-1.21.2
Tibia length0.51.42.1-0.5-1.01.2-1.2-1.51.3-1.3
Ambulatory time before self-admin0.30.51.81.31.10.2-0.2-0.10.5-0.5
Ambulatory time after self-admin0.70.82.21.5-0.10.7-0.7-0.71.1-1.1
Bone: tissue strength0.10.20.6-0.8-0.60.1-0.10.10.2-0.2
Total heroin consumption0.60.71.00.91.00.9-0.9-0.70.8-0.8
Bone: trabecular number0.30.40.6-0.6-0.1-0.70.70.6-0.80.8
Bone: trabecular spacing2.02.63.90.1-0.72.0-2.0-1.91.8-1.8
Bone: trabecular thickness0.91.11.9-0.40.3-1.41.41.2-1.11.1
Bone: trabecular tissue density0.50.71.00.70.1-0.90.91.0-0.90.9
Water consumed over 24 hours0.30.40.50.50.50.7-0.7-0.40.7-0.7
Number of responses in last shaping day3.94.37.52.71.21.9-1.9-2.02.2-2.2