LOC134479904

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IL	gene expression	LOC134479904	0.25	0.15	7.0e-04	0.03	0.06	0.04	0.05	5.7e-02	1.7e-02	3.1e-02	2.8e-02
2	IC	gene expression	LOC134479904	0.69	0.13	0.0e+00	0.36	0.45	0.41	0.43	8.8e-16	7.9e-21	1.3e-18	1.0e-19
3	PL	gene expression	LOC134479904	0.4	0.15	0.0e+00	0.26	0.33	0.34	0.34	3.4e-28	2.4e-37	2.4e-38	1.2e-38
4	Brain	gene expression	LOC134479904	0.13	0.07	2.7e-13	0.13	0.12	0.13	0.03	7.7e-12	1.0e-11	4.0e-12	5.2e-04
5	BLA	gene expression	LOC134479904	0.25	0.13	2.5e-11	0.21	0.17	0.18	0.17	3.0e-11	2.0e-09	1.2e-09	2.2e-09
6	OFC	gene expression	LOC134479904	0.23	0.15	5.6e-03	0.07	0.03	0.07	0.05	1.2e-02	7.1e-02	1.0e-02	2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
Bone: apparent density	0.3	0.5	1.5	0.0	-0.5	0.2	-0.5	-0.9	1.2
Area under the delay curve	0.5	0.7	0.9	0.9	0.9	0.9	-0.7	-0.8	-0.7
BMI with tail	5.1	17.7	22.2	-4.5	-4.7	-4.0	4.5	3.2	4.3
BMI without tail	2.0	10.8	14.3	-3.5	-3.6	-3.0	3.8	2.2	3.4
Body weight	7.2	31.4	37.4	-6.0	-6.1	-5.6	5.9	4.8	5.0
Weight adjusted by age	0.7	2.0	3.3	-1.5	-1.8	-1.3	0.9	1.0	1.8
Bone surface	0.1	0.2	0.7	-0.3	-0.6	-0.3	0.1	-0.1	0.8
Bone volume	0.2	0.4	1.0	0.2	-0.2	0.3	-0.6	-1.0	0.9
Breakpoint value in progressive ratio session	0.4	0.6	2.3	0.4	1.1	0.1	0.3	0.5	-1.5
Number of licking bursts	0.1	0.2	0.4	-0.3	-0.1	-0.2	0.6	0.6	-0.2
Context. condit. distance diff. score	1.9	2.3	2.5	-1.5	-1.5	-1.6	1.5	1.3	1.6
Locomotion velocity, session 1	0.2	0.2	0.4	-0.5	-0.6	-0.3	0.4	0.6	0.4
Locomotion distance, session 1	0.1	0.2	0.2	-0.4	-0.5	-0.4	-0.3	0.4	0.5
Locomotion velocity, session 2	3.0	3.6	6.8	2.0	1.4	2.0	-2.6	-2.1	-0.8
Locomotion distance, session 2	0.4	0.5	1.3	0.7	0.4	0.6	-1.1	-0.9	0.1
Locomotion velocity, session 3	3.6	4.1	5.0	-2.2	-2.2	-2.1	1.8	2.1	1.6
Locomotion distance, session 3	2.3	2.7	3.5	-1.7	-1.4	-1.9	1.9	1.8	1.1
Stereotopy head waving bouts, day 3	0.4	0.5	0.7	-0.8	-0.8	-0.8	0.4	0.7	0.6
Stereotopy head waving duration, day 3	0.3	0.3	0.9	-0.2	-0.6	-0.0	-0.6	-0.5	1.0
Locomotion velocity, session 7	0.6	0.6	1.7	-0.7	-0.9	-0.5	0.8	0.1	1.3
Locomotion distance, session 7	1.8	2.3	3.4	-1.4	-1.3	-1.5	1.8	1.0	1.7
Stereotopy head waving bouts, day 7	1.9	2.2	4.4	1.2	0.4	1.6	-2.1	-2.1	0.2
Stereotopy head waving duration, day 7	1.7	2.1	4.4	1.3	0.6	1.6	-2.1	-1.9	0.0
Locomotion velocity, session 8	0.1	0.1	0.2	-0.4	-0.4	-0.4	0.1	0.4	0.4
Locomotion distance, session 8	1.2	1.8	2.6	-1.3	-1.4	-1.5	1.1	1.1	1.6
Degree of sensitization distance	0.0	0.0	0.1	0.0	-0.0	0.1	-0.0	-0.3	0.4
Degree of sensitization stereotypy	3.8	4.2	7.8	2.0	1.2	2.3	-2.8	-2.6	-0.5
Conditioned locomotion	0.1	0.1	0.2	-0.4	-0.2	-0.5	0.3	0.4	0.1
Cocaine response after cond. corrected	0.9	1.4	1.8	1.2	1.3	1.1	-1.3	-0.8	-1.3
Cocaine response after cond. not corrected	1.0	1.5	2.2	1.3	1.3	1.2	-1.5	-1.1	-0.9
Cocaine response before conditioning	0.2	0.2	0.9	-0.2	-0.4	-0.1	0.4	-0.4	1.0
Saline control response	0.4	0.5	1.2	-0.5	-0.0	-0.7	1.0	1.1	-0.3
Bone: connectivity density	0.0	0.1	0.2	0.2	-0.1	0.2	-0.3	-0.4	0.2
Bone: cortical apparent density	0.8	1.2	1.8	1.2	1.1	1.3	-1.0	-1.2	-0.7
Bone: cortical area	2.8	4.5	8.6	-2.2	-2.5	-2.0	1.7	0.9	2.9
Bone: cortical porosity	0.3	0.3	1.2	-0.2	-0.5	-0.3	-0.2	-0.5	1.1
Bone: cortical porosity	0.8	0.9	2.4	-0.9	-1.2	-0.8	0.4	0.0	1.6
Bone: cortical thickness	0.7	1.2	3.7	-0.9	-1.3	-0.6	0.6	-0.2	1.9
Bone: cortical thickness	0.7	0.8	3.1	-0.5	-1.1	-0.3	-0.4	-0.5	1.8
Bone: cortical tissue density	0.9	1.4	2.0	1.3	1.2	1.4	-1.1	-1.2	-0.8
Condit. Reinf. active minus inactive responses	0.1	0.1	0.3	-0.0	0.2	-0.1	0.0	0.5	-0.6
Condit. Reinf. active-inactive response ratio	1.5	1.6	2.1	1.4	1.4	1.5	-1.0	-1.0	-1.3
Condit. Reinf. active responses	1.1	1.4	2.8	-1.3	-1.1	-1.3	1.0	1.7	0.3
Condit. Reinf. inactive responses	3.8	5.0	6.2	-2.5	-2.3	-2.5	1.9	2.5	1.5
Incentive salience index mean	0.4	0.5	1.4	-0.7	-0.5	-0.8	0.5	1.2	-0.1
Condit. Reinf. lever presses	0.5	0.8	1.4	-1.0	-1.0	-0.9	0.6	1.2	0.5
Condit. Reinf. active minus inactive responses	1.6	2.5	3.4	-1.8	-1.8	-1.5	1.5	1.4	1.3
Condit. Reinf. active-inactive response ratio	1.5	2.5	3.1	-1.8	-1.8	-1.6	1.4	1.4	1.4
Condit. Reinf. active responses	3.7	5.3	7.4	-2.6	-2.7	-2.2	2.2	1.9	2.1
Condit. Reinf. inactive responses	0.5	0.8	1.2	-0.9	-1.1	-0.7	0.9	0.5	0.9
Condit. Reinf. lever presses	0.2	0.2	0.6	-0.2	-0.7	0.1	0.2	-0.4	0.8
Condit. Reinf. lever reinforcers received	3.2	4.5	6.5	-2.3	-2.6	-2.0	2.1	1.6	2.0
Conditioned reinforcement - actives	0.3	1.1	1.6	-1.2	-1.3	-0.9	1.2	1.0	0.7
Conditioned reinforcement - inactives	0.6	1.5	2.4	-1.4	-1.6	-1.2	0.7	1.4	1.0
Conditioned locomotion	2.8	4.1	6.2	-2.2	-1.9	-2.2	2.1	2.5	1.0
Patch foraging indifference point 0 sec	0.8	2.3	3.7	-1.6	-1.4	-1.7	1.6	1.9	0.8
Patch foraging indifference point AUC	1.3	3.1	4.2	-1.9	-1.6	-1.8	2.0	1.9	1.1
Delay disc. indifference point, 0s delay	0.1	0.1	0.4	0.3	0.5	0.2	0.1	0.2	-0.6
Delay disc. indifference point, 16s delay	1.2	1.7	2.7	1.4	1.3	1.6	-1.0	-1.6	-0.8
Delay disc. indifference point, 2s delay	1.0	1.1	1.6	1.1	0.9	1.1	-1.3	-1.1	-0.7
Delay disc. indifference point, 24s delay	0.2	0.3	0.6	0.6	0.8	0.5	-0.4	-0.6	-0.4
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	0.3	0.2	0.3	-0.5	-0.2	0.0
Delay disc. indifference point, 8s delay	0.1	0.1	0.3	-0.0	0.3	-0.3	0.2	0.5	-0.5
Indifference point function ln k	0.2	0.5	0.7	0.8	0.7	0.7	-0.8	-0.8	-0.5
Indifference point function log k	0.2	0.5	0.7	0.8	0.7	0.7	-0.8	-0.8	-0.5
Patch foraging total patch changes 0 sec	0.5	1.5	2.4	-1.3	-1.1	-1.4	1.3	1.6	0.6
Patch foraging total patch changes 12 sec	0.9	1.2	3.4	-1.1	-0.7	-1.1	1.0	1.8	0.0
Patch foraging total patch changes 18 sec	1.7	4.0	5.3	-2.1	-2.3	-2.0	1.7	1.6	2.2
Patch foraging total patch changes 24 sec	0.0	0.1	0.3	0.2	0.4	0.2	-0.3	0.3	-0.5
Patch foraging total patch changes 6 sec	1.0	1.6	5.1	-1.1	-0.6	-1.2	1.2	2.3	-0.4
Patch foraging time to switch 0 sec	0.7	2.8	3.8	1.8	1.9	1.5	-1.8	-1.3	-1.6
Patch foraging water rate 0 sec	0.8	2.9	4.0	-1.8	-2.0	-1.5	1.9	1.3	1.7
Patch foraging water rate 12 sec	0.2	0.8	1.4	-0.9	-1.2	-0.6	0.8	0.3	1.1
Patch foraging water rate 18 sec	0.3	0.6	0.9	-0.9	-0.8	-0.7	0.9	0.9	0.3
Patch foraging water rate 24 sec	0.2	0.3	0.6	-0.5	-0.5	-0.5	0.7	0.8	-0.0
Patch foraging water rate 6 sec	2.0	3.0	5.6	-1.7	-2.3	-1.4	1.2	0.7	2.4
Seeking ratio, delayed vs. immediate footshock	0.3	0.4	0.9	-0.6	-0.7	-0.6	-0.1	1.0	0.4
Distance traveled before self-admin	0.4	0.8	1.1	-1.0	-0.8	-1.0	1.1	0.9	0.5
Distance traveled after self-admin	0.0	0.0	0.2	-0.1	0.1	-0.1	0.4	0.1	-0.2
Extensor digitorum longus weight	4.3	17.3	29.2	-4.4	-4.8	-4.1	3.3	2.2	5.4
Bone: elastic displacement	1.5	2.0	4.8	1.0	0.2	1.3	-1.8	-2.2	0.9
Bone: elastic work	0.8	1.1	2.7	0.1	-0.7	0.4	-1.1	-1.4	1.7
Bone: endosteal estimation	1.5	3.7	5.3	-2.1	-1.7	-2.3	1.9	2.1	1.3
Bone: endosteal perimeter	2.1	5.0	5.8	-2.4	-2.3	-2.4	2.4	1.9	2.1
Epididymis fat weight	0.6	2.9	7.0	-1.3	-0.3	-1.6	2.6	2.4	-0.6
Delta time in closed arm before/after self-admin	1.1	1.1	2.3	1.0	0.8	1.1	-1.5	-0.8	-0.8
Delta time in open arm before/after self-admin	0.0	0.0	0.0	-0.1	-0.0	-0.2	0.2	-0.1	0.1
Diff in mean of infusions in LGA sessions	0.3	0.6	0.8	0.8	0.9	0.7	-0.6	-0.6	-0.8
Delay discount exponential model param	0.6	0.8	1.1	-1.0	-1.0	-1.0	0.8	0.8	0.8
Extinction: sum of active levers before priming	1.3	1.9	2.8	1.5	1.5	1.3	-1.7	-0.9	-1.3
Active lever presses in extinction session 6	0.2	0.2	0.4	0.5	0.3	0.5	-0.5	-0.7	-0.1
Bone: final force	1.3	2.1	2.6	-1.6	-1.5	-1.6	1.4	1.3	1.3
Bone: final moment	0.7	1.2	1.4	-1.2	-1.1	-1.2	1.0	0.9	1.1
Food consumed during 24 hour testing period	0.4	0.9	2.2	-0.1	0.7	-0.3	1.0	1.2	-1.5
Glucose	0.9	1.5	3.4	1.2	1.7	0.9	-0.4	-0.2	-1.8
Heart weight	0.1	0.2	0.5	-0.1	-0.5	0.3	0.4	-0.7	0.6
Delay discount hyperbolic model param	0.7	0.9	1.0	-1.0	-1.0	-1.0	0.9	0.9	0.7
Intermittent access intake day 1-15 change	0.3	1.4	3.6	1.1	0.5	1.5	-1.9	-1.0	-0.6
Intermittent access intake escalation	0.4	1.9	4.4	1.3	0.6	1.7	-2.1	-1.3	-0.6
Intermittent access intake escalation 2	0.7	1.1	3.1	0.7	-0.3	1.1	-1.8	-1.3	0.5
Intermitt. access day 1 inactive lever presses	0.1	1.0	1.9	-1.0	-0.8	-1.2	0.5	1.4	0.6
Intermitt. access day 15 inactive lever presses	0.2	1.2	2.1	-1.3	-1.3	-1.0	0.9	1.5	0.5
Intermitt. access escalation Index	0.6	1.8	3.4	1.3	1.9	1.0	-1.2	-0.6	-1.7
Intermittent access day 1 total infusions	0.1	0.3	1.1	0.3	0.7	0.3	-0.1	0.2	-1.0
Intermittent access day 15 total infusions	1.0	2.3	3.6	1.5	1.2	1.8	-1.9	-1.2	-1.4
Intermittent access terminal intake (last 3 days)	0.5	0.8	1.8	0.9	0.6	1.0	-1.3	-0.7	-0.7
Intermittent access total infusions	0.2	0.2	0.5	0.4	0.3	0.5	-0.7	-0.2	-0.5
Intermittent access day 1 locomotion	0.3	0.5	1.2	-0.7	-0.2	-0.7	0.9	1.1	-0.5
Intermittent access day 15 total locomotion	0.4	1.6	2.7	-1.4	-1.3	-1.1	1.3	1.6	0.3
Intermittent access total locomotion	1.5	1.8	2.5	-1.5	-1.5	-1.3	1.2	1.6	0.7
Intermittent access standard deviation	0.1	0.6	1.2	-0.7	-1.1	-0.7	-0.1	0.8	0.9
Left kidney weight	0.3	2.6	5.0	-1.6	-1.0	-1.8	1.9	2.2	0.1
Right kidney weight	0.6	4.3	6.0	-2.2	-1.8	-2.2	2.4	2.4	1.0
Cocaine induced anxiety	0.1	0.3	0.5	0.5	0.5	0.5	-0.7	-0.4	-0.6
Post-drug Anxiety	0.2	0.2	0.6	0.2	-0.2	0.5	-0.1	-0.8	0.5
Baseline Anxiety	0.2	0.3	1.0	-0.1	-0.4	0.1	0.2	-0.6	1.0
Tail length	0.4	2.0	4.2	-1.4	-1.9	-1.1	1.0	0.4	2.0
Length with tail	2.1	9.5	12.1	-3.4	-3.5	-3.1	3.0	2.8	2.7
Length without tail	1.9	9.9	12.1	-3.5	-3.4	-3.3	3.0	3.3	2.3
Times rat made contact with spout	1.0	1.1	4.2	0.4	1.1	0.2	0.6	0.8	-2.0
Lifetime Intake	0.1	0.1	0.3	0.2	0.2	0.4	-0.5	0.0	-0.5
Liver weight, left	0.8	1.4	3.1	-1.3	-1.0	-1.2	1.2	1.8	0.1
Liver weight, right	1.4	2.5	2.9	-1.7	-1.7	-1.5	1.6	1.6	1.2
Locomotor activity	3.2	5.1	7.4	-2.4	-2.7	-2.2	1.9	1.8	2.4
Locomotor testing distance	1.0	2.5	3.3	-1.7	-1.8	-1.6	1.1	1.6	1.5
Locomotor testing rearing	0.3	1.3	2.0	-1.1	-0.9	-1.3	1.2	1.4	0.6
Locomotion in novel chamber	1.2	1.6	2.8	-1.3	-1.7	-1.1	0.7	1.0	1.4
Locomotion in novel chamber post-restriction	0.0	0.0	0.0	0.2	0.2	0.1	0.1	0.0	-0.0
Fecal boli incidents, locomotor time 1	0.2	0.6	1.4	0.9	0.9	0.8	-0.3	-1.2	-0.1
Change in fecal boli incidents, locomotor task	0.1	0.1	0.3	-0.2	-0.4	-0.1	-0.5	0.3	0.2
Time >=10cm from walls, locomotor time 1	2.2	2.7	3.7	-1.8	-1.7	-1.9	1.4	1.9	1.1
Bouts of movement, locomotor time 1	0.7	0.9	2.4	1.0	0.8	1.1	-0.2	-1.5	-0.2
Total resting periods, locomotor time 1	1.1	1.2	3.1	1.2	0.9	1.3	-0.6	-1.7	-0.3
Rest time, locomotor task time 1	1.9	3.0	4.0	1.9	2.0	1.9	-0.9	-1.7	-1.8
Distance moved, locomotor task time 1	0.2	0.6	2.1	-0.6	-1.0	-0.5	-0.1	-0.1	1.4
Vertical activity count, locomotor time 1	0.1	0.7	1.2	-0.8	-1.0	-0.8	0.3	0.6	1.1
Time >=10cm from walls, locomotor time 2	0.6	1.8	3.3	-1.3	-0.9	-1.7	1.4	1.8	0.4
Bouts of movement, locomotor time 2	0.2	0.8	1.5	1.0	1.2	1.0	-0.1	-0.9	-0.7
Total resting periods, locomotor time 2	0.2	0.9	1.8	1.1	1.3	1.1	-0.0	-0.9	-0.8
Rest time, locomotor task time 2	1.4	2.3	3.1	1.6	1.8	1.7	-0.8	-1.4	-1.7
Distance moved, locomotor task time 2	1.1	1.4	4.2	-1.0	-1.6	-1.0	-0.0	0.2	2.0
Vertical activity count, locomotor time 2	1.0	2.3	3.1	-1.5	-1.6	-1.7	1.2	1.3	1.8
Light reinforcement 1	0.0	0.2	0.6	0.3	0.6	0.2	0.1	0.0	-0.8
Light reinforcement 2	0.3	0.6	1.5	0.7	1.2	0.5	0.3	-0.0	-1.2
Bone: marrow area	1.5	3.8	5.4	-2.1	-1.7	-2.3	1.9	2.1	1.3
Bone: maximum diameter	2.6	5.3	6.3	-2.5	-2.3	-2.5	2.2	2.1	2.0
Bone: maximum force	2.2	4.3	5.2	-2.3	-2.2	-2.2	1.8	1.6	2.2
Bone: maximum moment	1.5	2.9	4.2	-1.9	-1.8	-1.9	1.4	1.1	2.0
Mean time between licks in bursts	0.1	0.4	1.1	0.1	-0.4	0.3	-0.5	-1.0	1.0
Mean num. licks in bursts	0.2	0.4	0.7	0.7	0.8	0.4	-0.4	-0.5	-0.9
Cd content in liver	1.8	2.0	4.6	1.3	0.7	1.5	-1.7	-2.1	0.2
Co content in liver	0.5	0.6	1.9	-0.1	-0.5	0.0	-0.8	-0.9	1.4
Cu content in liver	1.4	1.6	4.8	1.2	1.5	1.0	-0.6	-0.1	-2.2
Fe content in liver	0.7	0.8	2.4	-0.7	-0.1	-0.9	0.9	1.5	-0.6
K content in liver	2.2	2.1	6.2	-0.9	0.1	-1.4	1.4	2.5	-1.4
Mg content in liver	0.6	0.6	1.7	0.0	0.6	-0.4	0.5	1.1	-1.3
Mn content in liver	0.4	0.4	1.3	-0.5	-0.3	-0.5	0.4	1.1	-0.7
Na content in liver	1.2	1.4	4.3	0.1	1.0	-0.5	0.6	1.5	-2.1
Rb content in liver	0.5	0.6	2.3	0.5	0.9	0.2	0.0	0.6	-1.5
Se content in liver	0.1	0.2	0.3	-0.1	0.1	-0.2	0.5	0.5	-0.6
Sr content in liver	1.3	1.1	1.5	-1.1	-1.2	-1.0	0.9	0.7	1.2
Zn content in liver	1.9	2.3	4.8	-1.3	-0.6	-1.5	2.2	2.1	-0.3
Bone: minimum diameter	5.4	10.3	12.0	-3.5	-3.3	-3.4	3.1	2.7	3.2
Time in familiar zone, hab. session 1	0.2	0.3	0.8	0.5	0.5	0.2	-0.2	-0.9	0.4
Time in novel zone, hab. session 1	0.2	0.3	1.0	0.1	0.3	0.1	-0.0	0.6	-1.0
Total zone transitions, hab. session 1	0.9	1.3	4.9	-0.8	-1.4	-0.6	-0.1	-0.4	2.2
Total locomotion distance, hab. session 1	1.9	2.6	3.3	-1.7	-1.7	-1.7	1.6	1.1	1.8
Locomotion velocity, hab. session 1	1.7	2.4	3.5	-1.6	-1.8	-1.6	1.2	1.0	1.9
Time in familiar zone, hab. session 2	0.5	0.6	1.0	0.8	0.7	0.9	-0.6	-1.0	-0.2
Time in novel zone, hab. session 2	1.0	1.1	1.4	-1.2	-1.2	-1.2	0.8	1.0	0.8
Total zone transitions, hab. session 2	0.1	0.1	0.2	-0.2	-0.1	-0.5	-0.1	0.2	0.4
Total locomotion distance, hab. session 2	0.2	0.2	0.5	-0.4	-0.2	-0.7	0.4	0.6	0.2
Locomotion velocity, hab. session 2	0.1	0.1	0.2	-0.2	0.0	-0.4	0.2	0.5	-0.1
Novel to familiar place preference ratio	0.0	0.0	0.1	0.1	-0.0	0.1	-0.3	-0.0	-0.1
Novelty place preference	0.1	0.1	0.4	0.2	0.0	0.3	-0.6	-0.3	-0.0
Time in novel zone, NPP test	0.1	0.1	0.4	0.2	-0.0	0.3	-0.6	-0.4	0.1
Total zone transitions, NPP test	2.2	3.3	5.5	-1.9	-2.1	-1.8	1.3	1.2	2.3
Total locomotion distance, NPP test	2.2	3.1	4.0	-1.9	-1.9	-2.0	1.5	1.5	1.8
Locomotion velocity, NPP test	2.3	3.2	4.0	-1.9	-1.9	-2.0	1.6	1.5	1.8
Intraocular pressure	0.5	0.9	2.0	-0.8	-1.0	-0.7	1.1	0.2	1.4
Delta distance traveled before/after self-admin	0.1	0.1	0.1	0.3	0.3	0.2	0.0	-0.3	-0.1
Delta ambulatory time before/after self-admin	0.0	0.0	0.1	0.1	0.1	0.1	0.3	-0.2	-0.0
Parametrial fat weight	4.7	11.1	17.4	-3.4	-2.5	-3.7	4.0	4.2	1.2
Pavlov. Cond. lever latency	0.3	0.4	0.8	0.7	0.5	0.8	-0.6	-0.9	-0.3
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	0.3	0.4	0.4	-0.1	-0.2	-0.3
Pavlov. Cond. change in total contacts	0.4	0.5	0.7	0.7	0.7	0.8	-0.7	-0.5	-0.8
Pavlov. Cond. index score	0.0	0.0	0.0	-0.2	-0.2	-0.1	0.1	0.2	0.1
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.3	-0.2	-0.3	0.3	0.4	0.1
Pavlov. Cond. lever contacts	0.2	0.3	0.6	-0.5	-0.2	-0.6	0.6	0.8	-0.1
Pavlov. Cond. magazine entry number	0.0	0.0	0.0	-0.1	-0.1	-0.2	0.0	0.0	0.2
Pavlov. Cond. intertrial magazine entries	1.0	1.2	2.8	-1.0	-0.5	-1.4	1.1	1.7	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.2	-0.3	-0.1	-0.3	0.2	0.5	-0.2
Pavlov. Cond. response bias	0.0	0.0	0.0	0.0	0.1	0.1	-0.0	0.0	-0.2
Pavlov. Cond. lever latency	0.0	0.0	0.1	-0.1	0.0	-0.2	0.2	0.2	0.1
Pavlov. Cond. magazine entry latency	0.0	0.0	0.0	-0.0	-0.1	0.0	-0.1	-0.1	-0.0
Pavlov. Cond. change in total contacts	0.3	0.8	2.0	-0.8	-1.3	-0.4	0.1	-0.1	1.4
Pavlov. Cond. index score	0.0	0.0	0.0	-0.1	-0.2	-0.1	-0.2	0.1	0.0
Pavlov. Cond. latency score	0.0	0.0	0.1	-0.1	-0.2	-0.1	-0.3	-0.0	0.0
Pavlov. Cond. lever contacts	0.1	0.1	0.2	0.4	0.3	0.4	-0.4	-0.4	-0.3
Pavlov. Cond. magazine entry number	0.3	0.5	0.8	0.8	0.9	0.7	-0.4	-0.6	-0.6
Pavlov. Cond. intertrial magazine entries	0.3	0.7	2.0	-0.7	-0.2	-0.9	1.0	1.4	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.1	0.1	-0.3	-0.3	-0.3	0.1	0.3	0.1
Pavlov. Cond. response bias	0.0	0.1	0.2	-0.3	-0.5	-0.1	-0.0	0.1	0.3
Time in closed arm before self-admin	0.4	0.7	1.1	-0.8	-0.6	-1.1	0.8	0.9	0.5
Time in closed arm after self-admin	0.8	1.0	1.6	1.0	1.0	0.9	-1.3	-0.8	-0.8
Time in open arm before self-admin	0.1	0.1	0.3	-0.1	-0.4	-0.0	-0.2	0.0	0.5
Time in open arm after self-admin	0.1	0.1	0.2	-0.3	-0.2	-0.3	0.3	0.5	0.0
Bone: periosteal estimation	2.4	5.7	6.7	-2.6	-2.5	-2.6	2.1	1.9	2.5
Bone: periosteal perimeter	2.8	5.6	6.3	-2.5	-2.4	-2.5	2.5	1.7	2.4
Bone: post-yield work	1.3	2.2	4.1	-1.6	-0.9	-1.9	1.5	2.0	0.4
Progressive ratio test 1 active lever presses	0.1	0.2	0.7	-0.3	-0.1	-0.2	0.0	0.9	-0.7
Progressive ratio test 1 breakpoint	0.1	0.2	0.8	-0.3	-0.2	-0.3	0.0	0.9	-0.6
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.4	-0.1	-0.1	-0.0	-0.5	0.6	-0.4
Progressive ratio test 2 active lever presses	0.5	0.8	1.4	-1.0	-1.2	-0.7	0.7	1.1	0.4
Progressive ratio test 2 breakpoint	0.6	0.7	1.4	-0.9	-1.2	-0.6	0.6	1.1	0.4
Progressive ratio test 2 inactive lever presses	0.1	0.3	0.9	-0.6	-0.9	-0.3	0.3	0.5	0.5
Incentive Sensitization - Responses	0.3	0.9	2.0	-1.0	-1.4	-0.6	0.9	0.7	1.0
Incentive Sensitization - Breakpoint	0.3	0.7	1.5	-0.9	-1.2	-0.5	0.8	0.6	0.9
Sum of active levers in priming session hrs 5-6	0.8	0.7	1.1	-0.8	-0.9	-0.8	1.0	0.5	1.0
Progressive ratio	0.4	1.3	2.6	1.1	0.6	1.4	-1.3	-1.6	-0.3
Food seeking constrained by brief footshock	0.0	0.0	0.1	-0.1	0.2	-0.2	0.1	0.3	-0.3
Seeking ratio, punishment vs. effort	0.3	0.7	1.9	-0.7	-0.0	-1.0	0.9	1.4	-0.3
Retroperitoneal fat weight	1.2	5.4	6.8	-2.4	-2.2	-2.4	2.6	2.6	1.6
Reaction time number correct	0.5	1.7	3.0	-1.4	-1.0	-1.3	1.7	1.7	-0.0
Reaction time mean minus median	0.3	1.6	2.7	-1.2	-0.7	-1.5	1.6	1.6	0.4
Reaction time mean minus median AUC	0.0	0.2	0.5	-0.3	-0.0	-0.4	0.7	0.5	0.0
Reaction time num false alarms	0.2	0.4	0.7	-0.6	-0.3	-0.8	0.7	0.6	0.4
Reaction time num false alarms AUC	0.1	0.3	0.6	-0.5	-0.2	-0.8	0.7	0.4	0.4
Reaction time trials correct on left	0.5	1.7	3.0	-1.4	-1.0	-1.3	1.7	1.7	-0.0
Reaction time trials on left	0.6	2.0	3.4	-1.5	-1.0	-1.4	1.8	1.8	0.0
Reaction time mean	0.9	1.9	3.2	-1.3	-1.0	-1.6	1.8	1.5	0.9
Reaction time mean AUC	0.8	1.8	3.0	-1.3	-1.0	-1.5	1.7	1.5	0.8
Median of all reaction times	0.7	1.1	1.9	-1.0	-0.8	-1.2	1.4	1.0	0.8
Reaction time omissions	0.2	0.3	0.7	-0.5	-0.1	-0.8	0.6	0.8	-0.0
Reaction time false alarm rate	0.2	0.2	0.8	0.1	-0.1	-0.1	-0.3	-0.6	0.9
Reaction time premature initiation rate	0.1	0.2	0.4	-0.3	-0.4	-0.3	0.6	0.0	0.6
Reaction time premature initiations	0.2	0.5	1.2	-0.7	-0.5	-0.6	1.1	0.6	0.2
Std. dev. reaction times	0.9	2.9	4.9	-1.7	-1.1	-1.9	2.2	2.0	0.7
Reaction time trials completed	0.6	2.0	3.4	-1.5	-1.0	-1.4	1.8	1.8	0.0
Reaction time trials AUC	0.5	1.9	3.1	-1.5	-1.1	-1.4	1.8	1.7	0.2
Run reversals in cocaine runway, females	1.3	1.4	1.8	1.2	1.3	1.3	-1.1	-1.1	-1.1
Run reversals in cocaine runway, males	0.4	0.4	1.2	-0.6	-0.3	-0.5	1.1	0.8	0.0
Latency to leave start box in cocaine runway	7.3	10.1	11.9	3.5	3.4	3.3	-3.2	-2.9	-2.7
Latency to leave start box in cocaine runway, F	9.2	11.4	13.8	3.6	3.7	3.4	-3.5	-2.7	-3.2
Latency to leave start box in cocaine runway, M	0.9	0.9	2.2	1.0	0.6	1.1	-0.8	-1.5	0.0
Std. dev. time between licks in bursts	0.2	0.3	0.6	0.6	0.4	0.6	-0.6	-0.8	-0.1
Total sessions with >9 infusions	0.2	0.3	1.1	-0.5	-0.3	-0.3	0.1	1.1	-0.5
Short access day 1 total inactive lever presses	0.4	0.8	1.3	-1.0	-0.8	-0.9	1.1	1.1	0.4
Short access day 10 total inactive lever presses	0.2	1.2	2.0	-1.1	-0.8	-1.3	1.4	1.2	0.8
Short access day 1 total infusions	0.3	0.7	1.5	-0.8	-0.5	-0.8	1.1	1.2	-0.0
Short access day 10 total infusions	0.0	0.0	0.0	-0.1	-0.0	-0.1	-0.1	0.2	-0.1
Short access total infusions	0.0	0.0	0.2	0.1	0.1	0.2	-0.1	0.1	-0.4
Short access day 1 locomotion	1.3	2.2	4.0	-1.6	-1.3	-1.5	1.5	2.0	0.4
Short access day 10 total locomotion	0.2	1.0	2.8	-1.0	-0.4	-1.1	0.7	1.7	-0.4
Short access total locomotion	1.1	1.7	3.7	-1.5	-1.2	-1.3	1.1	1.9	0.2
One hour access (0.3 mA shock)	0.5	0.6	1.5	-0.8	-1.2	-0.4	0.5	0.3	1.0
Compulsive drug intake	0.5	0.8	1.1	0.9	0.9	0.9	-0.8	-1.1	-0.6
One hour access (shock baseline)	0.2	0.4	0.9	-0.7	-0.9	-0.6	0.3	0.7	0.6
Social response proportion	1.2	1.5	3.7	-1.0	-1.5	-0.9	0.9	0.0	1.9
Social responses	2.4	3.2	7.8	-1.5	-2.2	-1.2	1.6	0.1	2.8
Social time	0.2	0.3	1.1	-0.0	-0.3	-0.1	0.0	-0.6	1.0
Soleus weight	2.5	7.5	8.8	-3.0	-2.9	-2.8	2.8	2.4	2.6
Bone: stiffness	1.0	1.8	2.2	-1.5	-1.2	-1.5	1.5	1.3	1.0
Tibialis anterior weight	3.6	12.3	27.5	-3.5	-4.3	-3.0	2.2	1.2	5.2
Time to tail flick, vehicle, before self-admin	0.7	0.9	1.2	1.0	1.0	0.9	-1.1	-1.0	-0.6
Time to tail flick, vehicle, after self-admin	0.5	1.1	2.3	-0.8	-0.1	-1.1	1.3	1.5	-0.7
Time to tail flick, test, before self-admin	0.0	0.1	0.1	-0.1	-0.0	-0.3	0.4	0.2	0.2
Time to tail flick, test, after self-admin	0.3	0.3	0.6	0.7	0.5	0.7	-0.3	-0.8	0.0
Delta time to tail flick, vehicle, before/after SA	0.9	1.0	1.7	-1.0	-0.7	-1.1	1.3	1.1	0.2
Delta time to tail flick, test, before/after SA	0.2	0.3	0.6	-0.5	-0.6	-0.3	0.8	0.3	0.5
Tibia length	3.7	10.4	13.0	-3.6	-3.4	-3.5	3.0	3.0	2.8
Ambulatory time before self-admin	0.1	0.4	0.6	-0.7	-0.5	-0.8	0.8	0.7	0.3
Ambulatory time after self-admin	0.1	0.2	0.5	-0.4	-0.1	-0.4	0.7	0.4	-0.1
Bone: tissue strength	0.3	0.3	0.3	0.5	0.6	0.6	-0.4	-0.5	-0.5
Total heroin consumption	0.5	0.6	1.6	-0.4	0.3	-0.7	0.6	1.3	-0.9
Bone: trabecular number	0.5	1.0	2.4	0.4	-0.4	0.7	-1.0	-1.5	1.3
Bone: trabecular spacing	0.3	0.5	1.3	0.6	1.0	0.4	0.1	-0.0	-1.1
Bone: trabecular thickness	0.2	0.3	0.9	-0.1	-0.5	0.2	-0.5	-0.7	1.0
Bone: trabecular tissue density	1.1	2.0	5.7	1.3	1.7	1.3	-0.2	-0.1	-2.4
Water consumed over 24 hours	0.9	1.7	4.2	-0.8	0.1	-1.0	1.7	2.0	-1.3
Number of responses in last shaping day	0.3	0.3	1.3	-0.1	0.2	-0.4	-0.7	1.1	-0.5