Hub : Genes

LOC134479860

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	LOC134479860	0.1	0.05	9.2e-05	0.02	0.03	0.03	0.03	9.0e-04	2.2e-04	8.3e-04	3.5e-04
2	NAcc	gene expression	LOC134479860	0.1	0.04	4.3e-10	0.06	0.06	0.05	0.06	1.3e-09	9.0e-09	1.2e-08	8.3e-09
3	Brain	gene expression	LOC134479860	0.12	0.05	1.1e-08	0.09	0.08	0.08	0.09	9.0e-09	4.9e-08	7.6e-08	7.4e-09
4	pVTA	gene expression	LOC134479860	0.13	0.07	5.5e-07	0.1	0.1	0.1	0.1	3.5e-08	1.0e-08	4.0e-08	4.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.3	0.5	1.5	1.2	0.3	-0.6	-0.5
Area under the delay curve	1.7	2.7	3.6	-0.1	-1.9	1.9	1.8
BMI with tail	0.6	2.2	6.7	-1.1	-0.1	2.6	1.0
BMI without tail	0.3	1.8	3.2	-1.8	1.7	0.9	-0.6
Body weight	1.9	8.3	18.5	-4.3	3.1	1.9	-1.1
Weight adjusted by age	0.3	0.9	1.7	0.4	0.5	-1.3	-1.2
Bone surface	0.1	0.1	0.3	0.1	-0.1	0.6	0.3
Bone volume	0.0	0.1	0.2	0.5	0.0	0.3	0.0
Breakpoint value in progressive ratio session	1.1	2.1	3.6	1.9	-1.7	1.0	0.9
Number of licking bursts	0.1	0.2	0.4	0.5	0.2	0.6	0.4
Context. condit. distance diff. score	1.1	1.3	4.7	-2.2	0.1	0.5	0.4
Locomotion velocity, session 1	0.4	0.5	1.2	1.1	-0.4	-0.6	-0.5
Locomotion distance, session 1	0.1	0.2	0.4	0.6	-0.4	0.3	-0.1
Locomotion velocity, session 2	0.1	0.1	0.3	0.1	0.1	-0.5	-0.5
Locomotion distance, session 2	0.1	0.1	0.5	0.1	-0.2	0.7	0.0
Locomotion velocity, session 3	0.1	0.1	0.3	-0.1	-0.1	-0.6	-0.4
Locomotion distance, session 3	0.4	0.5	0.8	-0.8	-0.4	0.9	0.5
Stereotopy head waving bouts, day 3	1.0	1.2	3.7	1.9	0.0	-0.9	-0.5
Stereotopy head waving duration, day 3	1.0	1.2	2.4	1.5	0.2	-1.2	-0.9
Locomotion velocity, session 7	0.3	0.4	1.2	-1.1	0.1	0.4	0.2
Locomotion distance, session 7	0.2	0.2	0.4	-0.6	-0.4	0.4	0.3
Stereotopy head waving bouts, day 7	0.9	1.1	1.4	1.0	0.8	-1.2	-1.1
Stereotopy head waving duration, day 7	0.8	0.9	1.8	1.3	0.6	-1.0	-0.8
Locomotion velocity, session 8	0.6	0.7	1.1	-0.6	0.8	-1.1	-0.9
Locomotion distance, session 8	1.1	1.6	5.1	-2.3	0.2	1.1	0.2
Degree of sensitization distance	0.1	0.1	0.3	0.5	-0.3	-0.1	0.1
Degree of sensitization stereotypy	0.4	0.4	0.7	0.8	0.3	-0.7	-0.5
Conditioned locomotion	0.1	0.1	0.2	-0.3	-0.1	0.3	0.4
Cocaine response after cond. corrected	0.0	0.0	0.0	0.0	-0.1	0.1	0.1
Cocaine response after cond. not corrected	0.0	0.0	0.0	-0.1	-0.0	0.1	0.1
Cocaine response before conditioning	0.0	0.0	0.1	-0.3	0.2	-0.2	-0.2
Saline control response	0.5	0.7	0.9	-0.9	0.9	-0.6	-0.8
Bone: connectivity density	0.6	1.0	1.9	1.4	0.4	-1.1	-0.9
Bone: cortical apparent density	0.4	0.7	2.0	-1.4	0.8	0.1	-0.1
Bone: cortical area	0.1	0.1	0.5	-0.1	0.1	0.7	0.0
Bone: cortical porosity	0.1	0.2	0.4	0.3	0.2	-0.7	-0.3
Bone: cortical porosity	0.1	0.1	0.2	0.5	-0.0	-0.5	-0.1
Bone: cortical thickness	0.2	0.3	0.4	-0.1	0.6	-0.4	-0.7
Bone: cortical thickness	0.4	0.5	1.6	1.3	-0.4	-0.4	0.1
Bone: cortical tissue density	0.5	0.8	2.4	-1.5	0.9	0.0	-0.2
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	0.5	-0.2	-0.4	0.2
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.5	0.7	-0.6	0.2	0.6
Condit. Reinf. active responses	0.5	0.6	1.8	1.3	-0.2	-0.8	0.1
Condit. Reinf. inactive responses	0.6	0.7	2.4	1.5	-0.3	-0.7	0.0
Incentive salience index mean	0.3	0.4	0.8	0.6	0.5	-0.9	-0.5
Condit. Reinf. lever presses	0.5	0.7	1.0	0.5	1.0	-0.9	-0.9
Condit. Reinf. active minus inactive responses	0.0	0.1	0.1	0.3	-0.2	-0.2	-0.1
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.6	0.2	0.2	-0.8	-0.7
Condit. Reinf. active responses	0.1	0.1	0.1	0.4	-0.4	0.3	0.2
Condit. Reinf. inactive responses	0.5	0.7	1.1	0.6	-0.9	0.8	1.0
Condit. Reinf. lever presses	0.1	0.2	0.5	0.7	0.0	-0.2	-0.4
Condit. Reinf. lever reinforcers received	0.2	0.2	0.4	0.3	-0.5	0.6	0.4
Conditioned reinforcement - actives	0.4	1.6	2.5	0.1	1.3	-1.5	-1.6
Conditioned reinforcement - inactives	0.2	0.4	0.5	0.7	0.6	-0.7	-0.7
Conditioned locomotion	0.6	0.8	1.4	-0.4	0.9	-0.9	-1.2
Patch foraging indifference point 0 sec	0.0	0.1	0.2	0.2	0.5	-0.3	-0.2
Patch foraging indifference point AUC	0.4	1.0	1.5	0.4	1.2	-1.0	-1.1
Delay disc. indifference point, 0s delay	0.9	1.0	2.7	1.6	-0.9	0.5	0.4
Delay disc. indifference point, 16s delay	3.0	4.2	7.2	-0.3	-2.1	2.7	2.2
Delay disc. indifference point, 2s delay	0.3	0.3	0.6	-0.7	-0.6	0.6	0.2
Delay disc. indifference point, 24s delay	0.9	1.5	2.5	-0.6	-1.3	1.6	1.2
Delay disc. indifference point, 4s delay	0.1	0.1	0.2	-0.1	-0.5	0.1	0.3
Delay disc. indifference point, 8s delay	1.6	2.7	3.9	0.2	-2.0	1.7	2.0
Indifference point function ln k	0.2	0.7	1.1	-0.3	-0.9	1.1	0.9
Indifference point function log k	0.2	0.7	1.1	-0.3	-0.9	1.1	0.9
Patch foraging total patch changes 0 sec	0.0	0.1	0.2	0.4	0.4	-0.4	-0.3
Patch foraging total patch changes 12 sec	1.8	2.4	3.7	0.5	1.9	-1.6	-1.8
Patch foraging total patch changes 18 sec	1.2	2.9	5.0	-0.4	2.2	-1.8	-1.8
Patch foraging total patch changes 24 sec	0.5	1.6	2.8	-0.7	1.7	-1.1	-1.4
Patch foraging total patch changes 6 sec	0.1	0.2	0.4	0.6	0.6	-0.3	-0.3
Patch foraging time to switch 0 sec	0.0	0.1	0.4	-0.7	0.2	-0.1	0.1
Patch foraging water rate 0 sec	0.1	0.5	0.9	-0.9	0.5	0.9	0.0
Patch foraging water rate 12 sec	0.2	1.0	2.0	-0.8	1.4	-0.1	-1.1
Patch foraging water rate 18 sec	0.1	0.3	1.0	0.1	-0.3	1.0	0.3
Patch foraging water rate 24 sec	0.9	1.3	3.6	-1.9	0.5	1.2	-0.1
Patch foraging water rate 6 sec	1.1	1.6	2.8	-1.7	0.9	1.6	-0.2
Seeking ratio, delayed vs. immediate footshock	0.3	0.4	1.4	1.2	-0.1	-0.2	-0.4
Distance traveled before self-admin	0.0	0.1	0.2	0.2	-0.2	0.4	-0.1
Distance traveled after self-admin	1.0	1.7	2.4	0.6	-1.6	1.5	1.4
Extensor digitorum longus weight	0.0	0.2	0.4	0.2	-0.2	0.6	0.5
Bone: elastic displacement	1.0	1.2	2.6	1.6	-1.3	-0.6	0.5
Bone: elastic work	0.8	1.0	2.2	1.5	-1.2	-0.7	0.3
Bone: endosteal estimation	2.3	5.7	10.7	-0.1	-2.2	3.3	2.7
Bone: endosteal perimeter	1.3	3.1	6.9	-1.2	-1.0	2.6	1.7
Epididymis fat weight	0.3	1.4	2.9	-1.5	0.7	1.7	0.1
Delta time in closed arm before/after self-admin	0.2	0.2	0.4	-0.7	0.2	0.4	-0.0
Delta time in open arm before/after self-admin	1.2	1.5	4.4	2.1	-1.1	-0.1	0.6
Diff in mean of infusions in LGA sessions	0.1	0.2	0.5	0.7	-0.3	-0.4	-0.2
Delay discount exponential model param	1.6	2.2	3.0	0.3	1.7	-1.7	-1.7
Extinction: sum of active levers before priming	0.2	0.2	0.4	0.1	-0.6	0.6	0.4
Active lever presses in extinction session 6	0.6	0.6	1.0	0.5	-0.9	1.0	0.6
Bone: final force	0.8	1.3	2.8	0.2	-1.0	1.7	1.2
Bone: final moment	0.6	0.9	1.9	0.5	-0.9	1.4	0.9
Food consumed during 24 hour testing period	0.3	0.6	1.2	-0.4	1.1	-0.5	-0.9
Glucose	0.1	0.2	0.6	0.8	-0.1	0.0	-0.3
Heart weight	0.6	1.0	2.8	0.1	-0.7	1.7	0.9
Delay discount hyperbolic model param	1.4	1.8	2.5	0.5	1.5	-1.6	-1.5
Intermittent access intake day 1-15 change	0.4	2.3	3.8	-0.4	1.9	-1.4	-1.7
Intermittent access intake escalation	0.4	2.0	3.5	-0.3	1.9	-1.3	-1.6
Intermittent access intake escalation 2	0.7	1.1	1.9	-0.7	1.4	-1.0	-1.1
Intermitt. access day 1 inactive lever presses	0.0	0.5	1.6	1.3	-0.5	-0.5	0.2
Intermitt. access day 15 inactive lever presses	0.0	0.1	0.2	0.4	-0.3	-0.2	-0.2
Intermitt. access escalation Index	0.0	0.1	0.2	0.1	-0.1	-0.4	-0.2
Intermittent access day 1 total infusions	0.4	1.2	4.5	-2.1	0.5	0.3	-0.1
Intermittent access day 15 total infusions	0.6	1.6	3.0	-1.7	1.4	-0.4	-1.0
Intermittent access terminal intake (last 3 days)	0.8	1.4	4.1	-2.0	1.0	-0.0	-0.5
Intermittent access total infusions	1.0	1.2	4.1	-2.0	0.7	0.3	-0.2
Intermittent access day 1 locomotion	0.4	0.8	3.1	-1.7	0.2	0.2	0.1
Intermittent access day 15 total locomotion	0.5	2.0	2.5	-1.0	1.6	-1.5	-1.5
Intermittent access total locomotion	0.7	0.9	2.9	-1.7	0.7	-0.1	-0.4
Intermittent access standard deviation	0.3	1.8	3.1	-1.3	1.8	-0.9	-1.3
Left kidney weight	0.4	3.6	6.1	-2.1	2.5	-0.1	-2.0
Right kidney weight	0.3	1.9	3.5	-1.9	1.3	1.4	-0.6
Cocaine induced anxiety	0.6	1.8	2.7	1.3	-1.6	0.8	1.4
Post-drug Anxiety	0.5	0.6	1.1	0.8	-1.0	0.3	0.7
Baseline Anxiety	0.7	1.2	1.5	-1.2	1.1	-0.7	-1.2
Tail length	2.8	14.9	23.2	-4.7	4.8	-1.7	-3.5
Length with tail	3.8	17.0	28.5	-5.3	5.2	-0.8	-3.4
Length without tail	0.8	4.2	9.4	-3.1	2.3	0.8	-1.2
Times rat made contact with spout	2.4	2.7	5.4	-0.4	2.3	-1.2	-2.0
Lifetime Intake	1.0	1.2	4.3	-2.1	0.6	0.4	-0.0
Liver weight, left	2.1	3.7	6.2	-2.0	2.5	-0.7	-2.0
Liver weight, right	1.9	3.2	5.9	-0.9	2.4	-1.2	-2.2
Locomotor activity	0.5	0.8	1.4	-1.2	0.9	1.0	-0.4
Locomotor testing distance	0.5	1.1	3.2	-1.0	0.0	1.8	0.5
Locomotor testing rearing	0.0	0.2	0.5	-0.7	0.4	0.2	-0.3
Locomotion in novel chamber	0.3	0.4	1.2	-1.1	-0.2	0.4	0.4
Locomotion in novel chamber post-restriction	0.1	0.2	0.5	-0.7	0.4	-0.2	-0.3
Fecal boli incidents, locomotor time 1	0.0	0.1	0.2	-0.2	0.4	-0.2	-0.1
Change in fecal boli incidents, locomotor task	1.8	1.9	2.7	-0.8	-1.6	1.4	1.6
Time >=10cm from walls, locomotor time 1	1.2	1.5	2.6	0.3	-1.6	1.1	1.4
Bouts of movement, locomotor time 1	1.0	1.3	4.3	2.1	-0.7	0.3	0.7
Total resting periods, locomotor time 1	1.0	1.1	4.1	2.0	-0.5	-0.2	0.3
Rest time, locomotor task time 1	0.6	0.9	2.8	1.7	-0.3	-0.9	-0.1
Distance moved, locomotor task time 1	0.2	0.7	1.1	-1.1	1.0	-0.1	-0.7
Vertical activity count, locomotor time 1	0.2	1.3	3.5	-1.9	0.6	1.1	-0.1
Time >=10cm from walls, locomotor time 2	0.4	1.2	2.1	1.1	0.7	-1.4	-0.9
Bouts of movement, locomotor time 2	0.1	0.4	0.7	0.1	-0.8	0.6	0.8
Total resting periods, locomotor time 2	0.2	0.9	1.6	0.4	-1.3	0.9	1.1
Rest time, locomotor task time 2	1.1	1.8	3.1	1.0	-1.8	1.2	1.4
Distance moved, locomotor task time 2	2.0	2.7	4.0	0.1	2.0	-1.7	-1.9
Vertical activity count, locomotor time 2	0.9	2.0	4.4	-0.4	2.1	-0.7	-1.8
Light reinforcement 1	0.0	0.2	0.4	0.1	0.6	-0.1	-0.6
Light reinforcement 2	0.3	0.6	1.0	0.4	-0.6	0.9	1.0
Bone: marrow area	2.3	5.7	10.8	-0.1	-2.2	3.3	2.7
Bone: maximum diameter	0.8	1.6	4.8	-0.8	-0.4	2.2	1.0
Bone: maximum force	0.7	1.5	2.6	0.4	-1.3	1.6	1.2
Bone: maximum moment	0.6	1.2	1.8	0.8	-1.2	1.3	1.0
Mean time between licks in bursts	0.1	0.3	0.6	-0.0	-0.6	0.8	0.7
Mean num. licks in bursts	0.3	0.8	1.4	-0.6	0.8	-1.0	-1.2
Cd content in liver	0.6	0.7	1.1	1.0	-0.8	0.8	0.7
Co content in liver	0.1	0.1	0.2	-0.4	0.2	0.2	0.0
Cu content in liver	0.3	0.4	0.4	0.6	0.6	-0.6	-0.6
Fe content in liver	1.3	1.6	2.5	-0.7	-1.1	1.6	1.4
K content in liver	4.6	4.5	7.1	0.2	2.5	-2.7	-2.2
Mg content in liver	1.1	1.2	2.2	0.6	1.1	-1.5	-1.0
Mn content in liver	0.1	0.1	0.1	-0.3	0.2	0.3	0.3
Na content in liver	0.6	0.6	1.0	0.0	1.0	-1.0	-0.8
Rb content in liver	0.3	0.3	1.1	0.4	-0.0	-1.1	-0.2
Se content in liver	0.5	0.6	1.0	-0.5	-0.4	1.0	0.9
Sr content in liver	1.9	1.7	2.5	1.6	0.5	-1.4	-1.4
Zn content in liver	2.8	3.3	5.2	-1.2	2.3	-1.4	-2.0
Bone: minimum diameter	1.2	2.3	6.0	-1.4	-0.3	2.5	0.9
Time in familiar zone, hab. session 1	0.2	0.2	0.4	0.2	-0.6	0.5	0.5
Time in novel zone, hab. session 1	0.6	0.7	1.3	-0.6	-0.7	0.9	1.2
Total zone transitions, hab. session 1	0.3	0.4	1.2	-0.0	0.7	-0.0	-1.1
Total locomotion distance, hab. session 1	0.9	1.2	3.0	0.0	1.2	-0.6	-1.7
Locomotion velocity, hab. session 1	1.7	2.4	5.3	0.1	1.8	-1.1	-2.3
Time in familiar zone, hab. session 2	0.0	0.0	0.0	0.1	-0.1	-0.0	0.2
Time in novel zone, hab. session 2	0.7	0.8	1.2	0.3	-1.1	1.0	0.9
Total zone transitions, hab. session 2	0.2	0.3	0.8	-0.0	-0.5	0.9	0.3
Total locomotion distance, hab. session 2	0.1	0.1	0.2	0.4	-0.0	0.4	-0.2
Locomotion velocity, hab. session 2	0.1	0.1	0.1	0.3	0.0	0.4	-0.3
Novel to familiar place preference ratio	1.0	1.2	2.0	0.0	1.1	-1.4	-1.4
Novelty place preference	1.0	1.3	2.3	0.2	0.9	-1.5	-1.4
Time in novel zone, NPP test	0.7	0.8	1.4	0.1	0.8	-1.2	-1.1
Total zone transitions, NPP test	0.2	0.3	0.8	-0.0	-0.5	0.9	0.3
Total locomotion distance, NPP test	0.1	0.1	0.4	0.1	0.3	0.1	-0.6
Locomotion velocity, NPP test	0.1	0.2	0.5	0.1	0.4	-0.1	-0.7
Intraocular pressure	0.2	0.3	0.4	0.6	-0.6	0.4	0.5
Delta distance traveled before/after self-admin	0.3	0.4	0.6	0.5	-0.6	0.5	0.7
Delta ambulatory time before/after self-admin	0.6	1.1	1.7	0.8	-1.2	0.7	1.3
Parametrial fat weight	1.6	3.7	6.2	0.5	-1.8	2.5	2.2
Pavlov. Cond. lever latency	1.4	1.7	2.8	-1.0	-1.1	1.7	1.4
Pavlov. Cond. magazine entry latency	0.0	0.0	0.1	0.2	0.1	-0.0	-0.0
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	0.1	0.3	0.2	-0.2
Pavlov. Cond. index score	0.4	0.5	1.1	1.1	0.4	-0.6	-0.5
Pavlov. Cond. latency score	0.7	0.9	1.5	1.2	0.6	-1.0	-0.9
Pavlov. Cond. lever contacts	1.4	1.7	2.4	1.0	1.1	-1.5	-1.4
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	-0.1	0.2	-0.6	-0.4
Pavlov. Cond. intertrial magazine entries	2.6	3.2	4.6	-1.3	-1.3	2.1	2.1
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.3	1.2	1.1	0.2	-0.3	-0.3
Pavlov. Cond. response bias	0.2	0.3	0.3	0.5	0.6	-0.6	-0.5
Pavlov. Cond. lever latency	0.3	0.5	1.0	0.0	0.6	-1.0	-0.7
Pavlov. Cond. magazine entry latency	0.4	0.6	2.1	-1.5	0.5	-0.1	-0.3
Pavlov. Cond. change in total contacts	0.7	1.7	3.6	-1.9	-0.1	1.6	0.7
Pavlov. Cond. index score	0.5	0.8	2.5	-1.6	0.3	0.6	0.2
Pavlov. Cond. latency score	0.4	0.6	2.1	-1.5	0.2	0.6	0.2
Pavlov. Cond. lever contacts	0.5	0.7	1.8	-0.1	-0.7	1.3	0.8
Pavlov. Cond. magazine entry number	0.9	1.1	3.4	1.9	-0.3	-0.9	-0.3
Pavlov. Cond. intertrial magazine entries	0.2	0.4	1.1	1.1	-0.2	-0.5	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.9	3.1	-1.8	0.5	0.4	-0.1
Pavlov. Cond. response bias	0.4	0.5	1.3	-0.7	-0.3	1.1	0.6
Time in closed arm before self-admin	0.2	0.4	0.8	-0.9	0.5	-0.3	-0.5
Time in closed arm after self-admin	0.2	0.3	0.5	-0.6	-0.1	0.7	0.4
Time in open arm before self-admin	0.1	0.1	0.4	0.6	-0.2	0.2	0.3
Time in open arm after self-admin	1.3	1.4	3.5	1.9	-1.2	0.1	0.8
Bone: periosteal estimation	1.5	3.5	7.7	-0.5	-1.5	2.8	2.0
Bone: periosteal perimeter	0.8	1.7	3.7	-0.5	-0.9	1.9	1.3
Bone: post-yield work	0.2	0.4	0.9	-0.2	-0.5	1.0	0.5
Progressive ratio test 1 active lever presses	1.8	3.1	7.9	-2.8	1.7	-0.2	-1.2
Progressive ratio test 1 breakpoint	1.9	3.2	7.9	-2.8	1.8	-0.3	-1.3
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.1	-0.3	0.4	-0.2	-0.2
Progressive ratio test 2 active lever presses	1.3	1.9	2.7	-1.5	1.6	-0.9	-1.3
Progressive ratio test 2 breakpoint	1.6	2.1	2.9	-1.6	1.7	-1.0	-1.3
Progressive ratio test 2 inactive lever presses	0.2	0.7	1.1	-0.3	0.8	-1.0	-1.0
Incentive Sensitization - Responses	0.6	1.5	2.6	-0.9	1.6	-1.2	-1.2
Incentive Sensitization - Breakpoint	0.6	1.4	2.3	-0.8	1.5	-1.2	-1.1
Sum of active levers in priming session hrs 5-6	1.2	1.2	2.0	0.8	1.0	-1.0	-1.4
Progressive ratio	0.5	1.5	2.2	-1.0	-1.4	0.9	1.5
Food seeking constrained by brief footshock	1.9	2.3	6.7	-2.6	1.4	-0.5	-0.7
Seeking ratio, punishment vs. effort	0.6	1.4	2.5	0.0	1.6	-0.9	-1.5
Retroperitoneal fat weight	0.3	1.5	3.1	-1.8	1.4	0.8	-0.6
Reaction time number correct	0.1	0.4	0.7	0.3	-0.7	0.8	0.6
Reaction time mean minus median	0.1	0.7	2.1	1.5	-0.6	-0.6	-0.4
Reaction time mean minus median AUC	0.1	1.0	2.2	1.5	-0.2	-1.0	-0.8
Reaction time num false alarms	0.3	0.6	1.7	1.3	0.0	-0.7	-0.1
Reaction time num false alarms AUC	0.3	0.8	2.7	1.6	-0.4	-0.5	0.2
Reaction time trials correct on left	0.1	0.4	0.7	0.3	-0.7	0.8	0.6
Reaction time trials on left	0.1	0.5	0.7	0.4	-0.7	0.8	0.7
Reaction time mean	0.2	0.4	0.7	0.1	-0.7	0.8	0.5
Reaction time mean AUC	0.1	0.2	0.3	-0.0	-0.5	0.6	0.3
Median of all reaction times	0.4	0.6	1.5	-0.6	-0.6	1.2	0.7
Reaction time omissions	1.1	1.8	3.0	1.6	-1.7	0.4	1.1
Reaction time false alarm rate	0.3	0.4	1.2	1.1	-0.1	-0.7	0.0
Reaction time premature initiation rate	0.8	1.3	3.0	1.7	-0.7	1.2	0.5
Reaction time premature initiations	0.3	1.0	2.8	1.7	-0.5	1.0	0.3
Std. dev. reaction times	0.2	0.8	2.4	1.5	-0.8	-0.4	-0.1
Reaction time trials completed	0.1	0.5	0.7	0.4	-0.7	0.8	0.7
Reaction time trials AUC	0.2	0.5	1.0	0.3	-0.7	1.0	0.7
Run reversals in cocaine runway, females	0.1	0.1	0.2	0.1	0.1	-0.1	-0.5
Run reversals in cocaine runway, males	0.1	0.1	0.3	-0.0	0.3	-0.4	-0.5
Latency to leave start box in cocaine runway	0.1	0.1	0.3	-0.1	0.5	-0.1	-0.4
Latency to leave start box in cocaine runway, F	0.1	0.2	0.2	0.3	-0.4	0.4	0.4
Latency to leave start box in cocaine runway, M	1.6	1.6	2.4	-0.3	1.6	-1.2	-1.5
Std. dev. time between licks in bursts	0.6	1.2	2.0	0.5	-1.4	1.0	1.2
Total sessions with >9 infusions	0.7	0.9	2.5	-1.6	0.9	0.2	-0.3
Short access day 1 total inactive lever presses	0.1	0.1	0.2	-0.2	-0.3	0.4	0.5
Short access day 10 total inactive lever presses	0.1	1.0	2.2	1.5	-0.9	-0.9	-0.1
Short access day 1 total infusions	0.3	0.6	1.2	-1.1	-0.5	0.7	0.6
Short access day 10 total infusions	0.7	1.1	3.8	-1.9	0.6	0.4	0.0
Short access total infusions	0.5	0.7	2.7	-1.6	0.2	0.4	0.1
Short access day 1 locomotion	0.2	0.4	0.6	-0.3	0.8	-0.4	-0.8
Short access day 10 total locomotion	0.1	0.5	0.9	-0.5	-0.7	0.5	0.9
Short access total locomotion	0.7	1.1	1.8	-0.8	1.3	-0.9	-1.1
One hour access (0.3 mA shock)	3.7	4.4	7.4	-2.7	2.4	-1.0	-1.8
Compulsive drug intake	0.5	0.7	1.0	-0.6	0.9	-1.0	-0.8
One hour access (shock baseline)	0.8	2.1	3.1	-1.7	1.7	-0.7	-1.4
Social response proportion	0.4	0.5	1.7	-0.1	-0.4	1.3	0.5
Social responses	0.1	0.1	0.3	0.5	0.0	0.5	-0.2
Social time	0.3	0.5	1.1	0.7	0.7	-0.4	-1.0
Soleus weight	0.6	1.8	2.9	0.8	-1.3	1.7	1.4
Bone: stiffness	1.1	2.1	5.7	-0.2	-0.8	2.4	1.3
Tibialis anterior weight	0.9	3.1	4.5	0.9	-1.8	1.9	2.1
Time to tail flick, vehicle, before self-admin	2.5	3.1	5.2	-0.3	2.3	-1.4	-2.3
Time to tail flick, vehicle, after self-admin	0.3	0.6	1.2	1.1	-0.9	0.1	0.6
Time to tail flick, test, before self-admin	1.0	1.1	1.7	-0.8	-0.6	1.3	1.3
Time to tail flick, test, after self-admin	0.2	0.2	0.4	-0.4	-0.3	0.6	0.3
Delta time to tail flick, vehicle, before/after SA	2.2	2.4	4.4	0.7	-2.1	1.0	1.9
Delta time to tail flick, test, before/after SA	0.5	0.7	1.0	0.7	0.3	-1.0	-1.0
Tibia length	2.3	6.4	14.7	-3.8	2.8	0.4	-1.7
Ambulatory time before self-admin	0.0	0.1	0.4	0.3	0.3	-0.1	-0.6
Ambulatory time after self-admin	0.7	1.2	1.6	0.6	-1.2	1.3	1.1
Bone: tissue strength	0.2	0.2	0.5	0.2	-0.3	0.7	0.4
Total heroin consumption	2.5	2.9	3.9	1.5	-2.0	1.8	1.5
Bone: trabecular number	0.3	0.5	1.4	1.2	0.2	-0.6	-0.4
Bone: trabecular spacing	0.1	0.1	0.4	0.0	-0.1	-0.7	-0.4
Bone: trabecular thickness	0.3	0.4	0.6	0.4	0.8	-0.5	-0.7
Bone: trabecular tissue density	0.1	0.2	0.5	-0.7	0.4	0.1	-0.0
Water consumed over 24 hours	0.8	1.5	3.4	-0.3	1.8	-0.9	-1.3
Number of responses in last shaping day	0.3	0.4	1.5	-1.2	0.2	-0.3	-0.2